Home Fluorides 51773-92-3
51773-92-3,MFCD00797519
Catalog No.:AA00I969

51773-92-3 | (R)-[2,8-bis(trifluoromethyl)quinolin-4-yl](2S)-piperidin-2-ylmethanol hydrochloride

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50mg
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250mg
>98.0%(HPLC)
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1g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I969
Chemical Name:
(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl](2S)-piperidin-2-ylmethanol hydrochloride
CAS Number:
51773-92-3
Molecular Formula:
C17H17ClF6N2O
Molecular Weight:
414.7731
MDL Number:
MFCD00797519
SMILES:
O[C@@H](c1cc(nc2c1cccc2C(F)(F)F)C(F)(F)F)[C@H]1CCCCN1.Cl
Properties
Properties
 
Form:
Solid  
MP:
250-254?C  
Solubility:
DMSO: 38 mg/mL, soluble  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
483  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Literature

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Journal: The Lancet. Infectious diseases 20170601

Title: Hippocampal GABAergic interneurons coexpressing alpha7-nicotinic receptors and connexin-36 are able to improve neuronal viability under oxygen-glucose deprivation.

Journal: Brain research 20150807

Title: Carboxymefloquine, the major metabolite of the antimalarial drug mefloquine, induces drug-metabolizing enzyme and transporter expression by activation of pregnane X receptor.

Journal: Antimicrobial agents and chemotherapy 20150101

Title: Formulation and evaluation of Pheroid vesicles containing mefloquine for the treatment of malaria.

Journal: The Journal of pharmacy and pharmacology 20140101

Title: Concise synthesis and antimalarial activity of all four mefloquine stereoisomers using a highly enantioselective catalytic borylative alkene isomerization.

Journal: Angewandte Chemie (International ed. in English) 20130729

Title: 4-Amino-7-chloroquinolines: probing ligand efficiency provides botulinum neurotoxin serotype A light chain inhibitors with significant antiprotozoal activity.

Journal: Journal of medicinal chemistry 20130725

Title: Inhibition of autophagy and induction of breast cancer cell death by mefloquine, an antimalarial agent.

Journal: Cancer letters 20121230

Title: Spontaneous activity in the developing gerbil auditory cortex in vivo involves GABAergic transmission.

Journal: Neuroscience 20121213

Title: Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study.

Journal: The Lancet. Infectious diseases 20121101

Title: Inhibitory effects of pepstatin A and mefloquine on the growth of Babesia parasites.

Journal: The American journal of tropical medicine and hygiene 20121003

Title: Pharmacokinetic considerations in the repositioning of mefloquine for treatment of progressive multifocal leukoencephalopathy.

Journal: Clinical neurology and neurosurgery 20121001

Title: Limitations of postmarketing surveillance in the analysis of risk of pregnancy loss associated with maternal mefloquine exposure.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20121001

Title: Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose.

Journal: Journal of medicinal chemistry 20120913

Title: Primaquine for reducing Plasmodium falciparum transmission.

Journal: The Cochrane database of systematic reviews 20120912

Title: Tolerability of mefloquine intermittent preventive treatment for malaria in HIV-infected pregnant women in Benin.

Journal: Journal of acquired immune deficiency syndromes (1999) 20120901

Title: Mefloquine gap junction blockade and risk of pregnancy loss.

Journal: Biology of reproduction 20120901

Title: [New combination therapy against malaria].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20120821

Title: Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors.

Journal: Journal of biomolecular screening 20120801

Title: Identification of (+)-erythro-mefloquine as an active enantiomer with greater efficacy than mefloquine against Mycobacterium avium infection in mice.

Journal: Antimicrobial agents and chemotherapy 20120801

Title: Favourable outcome of progressive multifocal leukoencephalopathy with mefloquine treatment in combination with antiretroviral therapy in an HIV-infected patient.

Journal: International journal of STD & AIDS 20120801

Title: Efficacy of mefloquine to progressive multifocal leukoencephalopathy initially presented with parkinsonism.

Journal: Clinical neurology and neurosurgery 20120701

Title: Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.

Journal: Cell 20120608

Title: Hallucinations and persecutory delusions in mefloquine-associated suicide.

Journal: The American journal of forensic medicine and pathology 20120601

Title: Histopathological changes of juvenile Schistosoma japonicum harbored in mice treated orally with mefloquine at a smaller single dose.

Journal: Parasitology research 20120601

Title: Confocal laser scanning microscopic observation on adult Schistosoma japonicum harbored in mice following treatment with single-dose mefloquine.

Journal: Parasitology research 20120601

Title: Pregnancy and fetal outcomes after exposure to mefloquine in the pre- and periconception period and during pregnancy.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120601

Title: Suppression of autophagy exacerbates Mefloquine-mediated cell death.

Journal: Neuroscience letters 20120502

Title: Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.

Journal: Acta tropica 20120501

Title: Limbic encephalopathy and central vestibulopathy caused by mefloquine: a case report.

Journal: Travel medicine and infectious disease 20120501

Title: Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia.

Journal: The American journal of tropical medicine and hygiene 20120501

Title: A case of imported Plasmodium malariae malaria.

Journal: Annals of laboratory medicine 20120501

Title: [Study progress on mefloquine against schistosomes and other helminths].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20120430

Title: Pyronaridine-artesunate versus mefloquine plus artesunate for malaria.

Journal: The New England journal of medicine 20120405

Title: Mefloquine interferes with glycolysis in schistosomula of Schistosoma mansoni via inhibition of enolase.

Journal: Parasitology 20120401

Title: In vitro assessment of drug resistance in Plasmodium falciparum in five States of India.

Journal: The Indian journal of medical research 20120401

Title: Mirtazapine and mefloquine therapy for progressive multifocal leukoencephalopathy in a patient infected with human immunodeficiency virus.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120315

Title: Further studies on mefloquine and praziquantel alone or interaction of both drugs against Schistosoma japonicum in vitro.

Journal: Parasitology research 20120301

Title: High dose artesunate in combination with mefloquine: pharmacovigilance in the Venezuelan Amazon.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20120301

Title: Anti-malarial chemoprophylaxis following evacuation from Afghanistan.

Journal: Journal of the Royal Army Medical Corps 20120301

Title: Determining the absolute configuration of (+)-mefloquine HCl, the side-effect-reducing enantiomer of the antimalaria drug Lariam.

Journal: Journal of the American Chemical Society 20120215

Title: Ultrastructural alterations of juvenile Schistosoma japonicum harbored in mice following mefloquine administration.

Journal: Parasitology research 20120201

Title: Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine.

Journal: Journal of medicinal chemistry 20120112

Title: Mefloquine-oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113.

Journal: Bioorganic & medicinal chemistry 20120101

Title: Biased measurement of neuropsychiatric adverse effects of pediatric mefloquine treatment.

Journal: The Pediatric infectious disease journal 20120101

Title: Extracellular heme enhances the antimalarial activity of artemisinin.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Randomized, prospective, three-arm study to confirm the auditory safety and efficacy of artemether-lumefantrine in Colombian patients with uncomplicated Plasmodium falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20120101

Title: Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model.

Journal: Malaria journal 20120101

Title: Akinetic mutism caused by HIV-associated progressive multifocal leukoencephalopathy was successfully treated with mefloquine: a serial multimodal MRI Study.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans.

Journal: Malaria journal 20120101

Title: Consequences of gestational malaria on birth weight: finding the best timeframe for intermittent preventive treatment administration.

Journal: PloS one 20120101

Title: Mefloquine improved progressive multifocal leukoencephalopathy in a patient with systemic lupus erythematosus.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Therapy of uncomplicated falciparum malaria in Europe: MALTHER - a prospective observational multicentre study.

Journal: Malaria journal 20120101

Title: Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India.

Journal: Malaria journal 20120101

Title: Neuropharmacokinetic heterogeneity of mefloquine in the treatment of progressive multifocal leukoencephalopathy.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Effect of artesunate-mefloquine fixed-dose combination in malaria transmission in Amazon basin communities.

Journal: Malaria journal 20120101

Title: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997-2007.

Journal: Malaria journal 20120101

Title: Artemisinin resistance containment project in Thailand. II: Responses to mefloquine-artesunate combination therapy among falciparum malaria patients in provinces bordering Cambodia.

Journal: Malaria journal 20120101

Title: Mefloquine neurotoxicity and gap junction blockade: critical insights in drug repositioning.

Journal: Neurotoxicology 20111201

Title: Case report: Peripheral polyneuropathy and mefloquine prophylaxis.

Journal: The American journal of tropical medicine and hygiene 20111201

Title: Pharmacokinetics of antimalarials in pregnancy: a systematic review.

Journal: Clinical pharmacokinetics 20111101

Title: Eritrean and Sudanese migrants presenting with malaria in Israel.

Journal: Travel medicine and infectious disease 20111101

Title: Prophylactic use of antimalarials during pregnancy.

Journal: Canadian family physician Medecin de famille canadien 20111101

Title: Pharmacodynamics of mefloquine and praziquantel combination therapy in mice harbouring juvenile and adult Schistosoma mansoni.

Journal: Memorias do Instituto Oswaldo Cruz 20111101

Title: Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase.

Journal: Neurotoxicology 20111001

Title: Mefloquine for uncomplicated Plasmodium falciparum malaria in children.

Journal: The Pediatric infectious disease journal 20111001

Title: Progressive multifocal leukoencephalopathy associated with isolated CD8+ T-lymphocyte deficiency mimicking tumefactive MS.

Journal: Journal of neurovirology 20111001

Title: The pharmacogenetics of antimalaria artemisinin combination therapy.

Journal: Expert opinion on drug metabolism & toxicology 20111001

Title: Sensitivity of Plasmodium vivax to chloroquine, mefloquine, artemisinin and atovaquone in north-western Thailand.

Journal: Wiener klinische Wochenschrift 20111001

Title: Quality of essential drugs in tropical countries: evaluation of antimalarial drugs in the Brazilian Health System.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20111001

Title: [Mood disorder after malaria prophylaxis with mefloquine (two case reports)].

Journal: L'Encephale 20111001

Title: Nonspecific effects of the gap junction blocker mefloquine on fast hippocampal network oscillations in the adult rat in vitro.

Journal: Neuroscience 20110929

Title: Structure-activity relationships of 4-position diamine quinoline methanols as intermittent preventative treatment (IPT) against Plasmodium falciparum.

Journal: Journal of medicinal chemistry 20110922

Title: Polymorphisms of molecular markers of antimalarial drug resistance and relationship with artesunate-mefloquine combination therapy in patients with uncomplicated Plasmodium falciparum malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 20110901

Title: Mefloquine effects on ventral tegmental area dopamine and GABA neuron inhibition: a physiologic role for connexin-36 GAP junctions.

Journal: Synapse (New York, N.Y.) 20110801

Title: Interactions of mefloquine with praziquantel in the Schistosoma mansoni mouse model and in vitro.

Journal: The Journal of antimicrobial chemotherapy 20110801

Title: Clarithromycin, a cytochrome P450 inhibitor, can reverse mefloquine resistance in Plasmodium yoelii nigeriensis- infected Swiss mice.

Journal: Parasitology 20110801

Title: Unified patch clamp protocol for the characterization of Pannexin 1 channels in isolated cells and acute brain slices.

Journal: Journal of neuroscience methods 20110715

Title: Mefloquine damage vestibular hair cells in organotypic cultures.

Journal: Neurotoxicity research 20110701

Title: Intermittent preventive treatment of malaria in pregnancy: at the crossroads of public health policy.

Journal: Tropical medicine & international health : TM & IH 20110701

Title: Distribution of mefloquine in the blood of Thai patients with acute uncomplicated falciparum malaria following administration of therapeutic doses of artesunate.

Journal: European journal of clinical pharmacology 20110701

Title: Plasmodium knowlesi reinfection in human.

Journal: Emerging infectious diseases 20110701

Title: Efficacy of mefloquine treatment and genetic profiles in uncomplicated Plasmodium falciparum malaria in southern Lao PDR.

Journal: The Southeast Asian journal of tropical medicine and public health 20110701

Title: Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones.

Journal: Organic letters 20110617

Title: 2,4-diarylthiazole antiprion compounds as a novel structural class of antimalarial leads.

Journal: Bioorganic & medicinal chemistry letters 20110615

Title: Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication.

Journal: Experimental parasitology 20110601

Title: Preparation, characterization and dissolution enhancement of mefloquine hydrochloride-betaCD inclusion complex.

Journal: Die Pharmazie 20110601

Title: Evaluation of the physical properties and stability of two lipid drug delivery systems containing mefloquine.

Journal: International journal of pharmaceutics 20110516

Title: Plasmodium falciparum infection during suppressive prophylaxis with mefloquine does not induce an antibody response to merozoite surface protein-1(42).

Journal: The American journal of tropical medicine and hygiene 20110505

Title: Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment.

Journal: American journal of therapeutics 20110501

Title: A single, low, oral dose of a 5-carbon-linked trioxane dimer orthoester plus mefloquine cures malaria-infected mice.

Journal: Bioorganic & medicinal chemistry letters 20110501

Title: In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs.

Journal: Antimicrobial agents and chemotherapy 20110501

Title: Mefloquine in the treatment of progressive multifocal leukoencephalopathy.

Journal: Journal of neurology, neurosurgery, and psychiatry 20110401

Title: Effect of artesunate and mefloquine in combination on the Fridericia corrected QT intervals in Plasmodium falciparum infected adults from Thailand.

Journal: Tropical medicine & international health : TM & IH 20110401

Title: The antimalarial drug mefloquine inhibits cardiac inward rectifier K+ channels: evidence for interference in PIP2-channel interaction.

Journal: Journal of cardiovascular pharmacology 20110401

Title: Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum.

Journal: PLoS genetics 20110401

Title: Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents.

Journal: Environmental and molecular mutagenesis 20110301

Title: Artesunate/mefloquine paediatric formulation vs. artemether/lumefantrine for the treatment of uncomplicated Plasmodium falciparum in Anonkoua kouté, Côte d'Ivoire.

Journal: Tropical medicine & international health : TM & IH 20110301

Title: Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.

Journal: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20110301

Title: Cured of fear of flying.

Journal: Travel medicine and infectious disease 20110301

Title: Enantiomeric separation of antimalarial drugs by capillary electrophoresis using neutral and negatively charged cyclodextrins.

Journal: Journal of pharmaceutical and biomedical analysis 20110220

Title: Azithromycin for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20110216

Title: Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies.

Journal: Journal of medicinal chemistry 20110210

Title: Prevention of malaria during pregnancy: assessing the effect of the distribution of IPTp through the national policy in Benin.

Journal: The American journal of tropical medicine and hygiene 20110204

Title: Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum.

Journal: Parasitology research 20110201

Title: Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini: a randomised, exploratory, open-label, phase 2 trial.

Journal: The Lancet. Infectious diseases 20110201

Title: The intradermal route for inoculation of sporozoites of rodent malaria parasites for immunological studies.

Journal: Parasite immunology 20110201

Title: Electrical synapses control hippocampal contributions to fear learning and memory.

Journal: Science (New York, N.Y.) 20110107

Title: Biowaiver monographs for immediate release solid oral dosage forms: mefloquine hydrochloride.

Journal: Journal of pharmaceutical sciences 20110101

Title: In-vitro culture of Plasmodium falciparum: utility of modified (RPNI) medium for drug-sensitivity studies using SYBR Green I assay.

Journal: Experimental parasitology 20110101

Title: Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo.

Journal: Experimental parasitology 20110101

Title: Schistosoma mansoni: schistosomicidal effect of mefloquine and primaquine in vitro.

Journal: Experimental parasitology 20110101

Title: Strain-specific immunity induced by immunization with pre-erythrocytic stages of Plasmodium chabaudi.

Journal: Parasite immunology 20110101

Title: Characterization of nonjunctional hemichannels in caterpillar cells.

Journal: Journal of insect science (Online) 20110101

Title: Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance.

Journal: PloS one 20110101

Title: Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice.

Journal: Malaria journal 20110101

Title: Molecular markers of resistance to sulphadoxine-pyrimethamine during intermittent preventive treatment of pregnant women in Benin.

Journal: Malaria journal 20110101

Title: Molecular analysis of pfatp6 and pfmdr1 polymorphisms and their association with in vitro sensitivity in Plasmodium falciparum isolates from the Thai-Myanmar border.

Journal: Acta tropica 20110101

Title: Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).

Journal: Malaria journal 20110101

Title: Development and validation of an HPLC method for mefloquine hydrochloride determination in tablet dosage form.

Journal: Journal of AOAC International 20110101

Title: Use of mefloquine in children - a review of dosage, pharmacokinetics and tolerability data.

Journal: Malaria journal 20110101

Title: A randomized, double-blind, placebo-controlled study to investigate the safety, tolerability, and pharmacokinetics of single enantiomer (+)-mefloquine compared with racemic mefloquine in healthy persons.

Journal: The American journal of tropical medicine and hygiene 20101206

Title: A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.

Journal: The American journal of tropical medicine and hygiene 20101206

Title: Artemisinin-based combination therapies and their introduction in Japan.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20101201

Title: Synthesis and antitubercular activity of new mefloquine-oxazolidine derivatives.

Journal: European journal of medicinal chemistry 20101201

Title: Neuronal gap junctions are required for NMDA receptor-mediated excitotoxicity: implications in ischemic stroke.

Journal: Journal of neurophysiology 20101201

Title: Suicide by skull stab wounds: a case of drug-induced psychosis.

Journal: The American journal of forensic medicine and pathology 20101201

Title: GABAergic compensation in connexin36 knock-out mice evident during low-magnesium seizure-like event activity.

Journal: Brain research 20101111

Title: Effectiveness of mefloquine against Clonorchis sinensis in rats and Paragonimus westermani in dogs.

Journal: Parasitology research 20101101

Title: Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure.

Journal: The Journal of infectious diseases 20101101

Title: [A case of malarial hepatitis by Plasmodium vivax].

Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20101101

Title: Further study of (+/-)-mefloquinium chloride solvates. Crystal structures of the hemihydrate and monohydrate of (+/-)-mefloquinium chloride, from data collected at 120 K.

Journal: International journal of pharmaceutics 20101015

Title: Purified Plasmodium falciparum multi-drug resistance protein (PfMDR 1) binds a high affinity chloroquine analogue.

Journal: Molecular and biochemical parasitology 20101001

Title: Update on the diagnosis and treatment of food-borne trematode infections.

Journal: Current opinion in infectious diseases 20101001

Title: Residual antimalarial concentrations before treatment in patients with malaria from Cambodia: indication of drug pressure.

Journal: The Journal of infectious diseases 20101001

Title: Synergism between mefloquine and artemisinin and its enhancement by retinol in Plasmodium falciparum in vitro.

Journal: Wiener klinische Wochenschrift 20101001

Title: Sensitivity to artemisinin, mefloquine and quinine of Plasmodium falciparum in northwestern Thailand.

Journal: Wiener klinische Wochenschrift 20101001

Title: Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial.

Journal: The Lancet. Infectious diseases 20100909

Title: Crystal engineering to improve physicochemical properties of mefloquine hydrochloride.

Journal: Drug development and industrial pharmacy 20100901

Title: Further observation on histopathological alterations of adult Schistosoma japonicum harbored in mice following treatment with mefloquine at a smaller single dose.

Journal: Parasitology research 20100901

Title: Mefloquine induces oxidative stress and neurodegeneration in primary rat cortical neurons.

Journal: Neurotoxicology 20100901

Title: Postural orthostatic tachycardia syndrome: a case report of palpitations and dizziness following prophylactic mefloquine use.

Journal: International journal of clinical pharmacology and therapeutics 20100901

Title: Mefloquine adverse effects with atypical facial lesions in an overweight patient.

Journal: Travel medicine and infectious disease 20100901

Title: [Polymorphism at the MDR1 locus as a cause of mefloquine-induced psychosis].

Journal: Harefuah 20100901

Title: An outbreak of Plasmodium falciparum malaria in U.S. Marines deployed to Liberia.

Journal: The American journal of tropical medicine and hygiene 20100805

Title: Synergy of mefloquine activity with atorvastatin, but not chloroquine and monodesethylamodiaquine, and association with the pfmdr1 gene.

Journal: The Journal of antimicrobial chemotherapy 20100701

Title: Intravenous ibuprofen (IV-ibuprofen) controls fever effectively in adults with acute uncomplicated Plasmodium falciparum malaria but prolongs parasitemia.

Journal: The American journal of tropical medicine and hygiene 20100701

Title: Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.

Journal: The American journal of tropical medicine and hygiene 20100701

Title: [Progress in development of new antischistosomal drugs in recent years].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20100630

Title: Pannexin-I/P2X 7 purinergic receptor channels mediate the release of cardioprotectants induced by ischemic pre- and postconditioning.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100601

Title: Mania associated with mefloquine prophylaxis.

Journal: Journal of clinical psychopharmacology 20100601

Title: Tolerability and efficacy of a pediatric granule formulation of artesunate-mefloquine in young children from Cameroon with uncomplicated falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20100601

Title: In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire).

Journal: African health sciences 20100601

Title: Multiple genetic backgrounds of the amplified Plasmodium falciparum multidrug resistance (pfmdr1) gene and selective sweep of 184F mutation in Cambodia.

Journal: The Journal of infectious diseases 20100515

Title: Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100501

Title: Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent.

Journal: Neuro-oncology 20100501

Title: Letter to the editor of travel medicine and infectious disease.

Journal: Travel medicine and infectious disease 20100501

Title: Transmission electron microscopic observation on ultrastructural alterations in Schistosoma japonicum caused by mefloquine.

Journal: Parasitology research 20100401

Title: Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones.

Journal: Bioorganic & medicinal chemistry 20100401

Title: Action potential clamp and mefloquine sensitivity of recombinant 'I KS' channels incorporating the V307L KCNQ1 mutation.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100401

Title: In vitro sensitivity of Plasmodium falciparum to conventional and novel antimalarial drugs in Papua New Guinea.

Journal: Tropical medicine & international health : TM & IH 20100301

Title: Efficacy and safety of a new pediatric artesunate-mefloquine drug formulation for the treatment of uncomplicated falciparum malaria in Gabon.

Journal: Wiener klinische Wochenschrift 20100301

Title: Symmetrical peripheral gangrene in childhood falciparum malaria.

Journal: International journal of dermatology 20100301

Title: Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.

Journal: Acta tropica 20100201

Title: Mefloquine prescriptions in the presence of contraindications: prevalence among US military personnel deployed to Afghanistan, 2007.

Journal: Pharmacoepidemiology and drug safety 20100201

Title: Synthesis and antituberculosis activity of novel mefloquine-isoxazole carboxylic esters as prodrugs.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Tegumental alterations of adult Schistosoma japonicum harbored in mice treated with a single oral dose of mefloquine.

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20100201

Title: Morphological effects and tegumental alterations induced by mefloquine on schistosomula and adult flukes of Schistosoma mansoni.

Journal: Parasitology 20100101

Title: Activity of artemether and mefloquine against juvenile and adult Schistosoma mansoni in athymic and immunocompetent NMRI mice.

Journal: The American journal of tropical medicine and hygiene 20100101

Title: Imported chloroquine-resistant Plasmodium vivax in Singapore: case report and literature review.

Journal: Journal of travel medicine 20100101

Title: Compliance with a three-day course of artesunate-mefloquine combination and baseline anti-malarial treatment in an area of Thailand with highly multidrug resistant falciparum malaria.

Journal: Malaria journal 20100101

Title: Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols.

Journal: Malaria journal 20100101

Title: Duration of protection against clinical malaria provided by three regimens of intermittent preventive treatment in Tanzanian infants.

Journal: PloS one 20100101

Title: Plasmodium falciparum malaria and Parvovirus B19; a case of acute co-infection.

Journal: BMC infectious diseases 20100101

Title: Alternatives for malaria prophylaxis during the first trimester of pregnancy: our personal view.

Journal: Journal of travel medicine 20100101

Title: Experimental evolution of resistance to artemisinin combination therapy results in amplification of the mdr1 gene in a rodent malaria parasite.

Journal: PloS one 20100101

Title: An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.

Journal: PloS one 20100101

Title: Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression.

Journal: PloS one 20100101

Title: Cost-effectiveness analysis of malaria chemoprophylaxis for travellers to West-Africa.

Journal: BMC infectious diseases 20100101

Title: Declining in efficacy of a three-day combination regimen of mefloquine-artesunate in a multi-drug resistance area along the Thai-Myanmar border.

Journal: Malaria journal 20100101

Title: Artesunate-mefloquine combination therapy in acute Plasmodium falciparum malaria in young children: a field study regarding neurological and neuropsychiatric safety.

Journal: Malaria journal 20100101

Title: Anti-bacterial activity of intermittent preventive treatment of malaria in pregnancy: comparative in vitro study of sulphadoxine-pyrimethamine, mefloquine, and azithromycin.

Journal: Malaria journal 20100101

Title: Effects of anti-malarial drugs on the electrocardiographic QT interval modelled in the isolated perfused guinea pig heart system.

Journal: Malaria journal 20100101

Title: Mefloquine treatment in a patient suffering from progressive multifocal leukoencephalopathy after umbilical cord blood transplant.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Psoriasis triggered by mefloquine.

Journal: Skinmed 20100101

Title: The position of mefloquine as a 21st century malaria chemoprophylaxis.

Journal: Malaria journal 20100101

Title: [Long-term malaria prophylaxis with mefloquine: a study of adverse drug reactions].

Journal: Therapie 20100101

Title: Malaria: prevention in travellers.

Journal: BMJ clinical evidence 20100101

Title: Analysis of acetylcholine-induced membrane responses in vascular endothelial cells of the guinea-pig mesenteric artery using mefloquine as a gap junction blocker.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101

Title: Neuropeptides modulate compound postsynaptic potentials in basolateral amygdala.

Journal: Neuroscience 20091229

Title: Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose.

Journal: Journal of medicinal chemistry 20091210

Title: Mode of action and choice of antimalarial drugs for intermittent preventive treatment in infants.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20091201

Title: Further study on mefloquine concerning several aspects in experimental treatment of mice and hamsters infected with Schistosoma japonicum.

Journal: Parasitology research 20091201

Title: The in vitro effect of mefloquine and praziquantel against juvenile and adult Schistosoma japonicum.

Journal: Parasitology research 20091201

Title: Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria.

Journal: The American journal of tropical medicine and hygiene 20091201

Title: Mefloquine blockade of Pannexin1 currents: resolution of a conflict.

Journal: Cell communication & adhesion 20091201

Title: From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters.

Journal: Journal of medicinal chemistry 20091126

Title: Histopathological alteration of juvenile Schistosoma japonicum in mice following treatment with single-dose mefloquine.

Journal: Parasitology research 20091101

Title: Use of resazurin to detect mefloquine as an efflux-pump inhibitor in Pseudomonas aeruginosa and Escherichia coli.

Journal: Journal of microbiological methods 20091101

Title: Effectiveness of malaria chemoprophylaxis against Plasmodium falciparum infection in UK travellers: retrospective observational data.

Journal: Travel medicine and infectious disease 20091101

Title: Early diagnosis and treatment of falciparum malaria in Cambodian trauma patients.

Journal: The Southeast Asian journal of tropical medicine and public health 20091101

Title: Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial.

Journal: Lancet (London, England) 20091031

Title: Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine.

Journal: Organic & biomolecular chemistry 20091021

Title: Mefloquine has more adverse effects than other drugs for malaria prophylaxis.

Journal: BMJ (Clinical research ed.) 20091013

Title: Drugs for preventing malaria in travellers.

Journal: The Cochrane database of systematic reviews 20091007

Title: Plasmodium berghei-infection induces volume-regulated anion channel-like activity in human hepatoma cells.

Journal: Cellular microbiology 20091001

Title: In vitro antimalarial interactions between mefloquine and cytochrome P450 inhibitors.

Journal: Acta tropica 20091001

Title: Pharmacodynamic interaction between mefloquine and retinol in Plasmodium falciparum in vitro.

Journal: Wiener klinische Wochenschrift 20091001

Title: Travelers on beta-blockers: is malaria chemoprophylaxis dangerous?

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20091001

Title: Intermittent treatment for the prevention of malaria during pregnancy in Benin: a randomized, open-label equivalence trial comparing sulfadoxine-pyrimethamine with mefloquine.

Journal: The Journal of infectious diseases 20090915

Title: Effect of single-dose oral mefloquine on the morphology of adult Schistosoma japonicum in mice.

Journal: Parasitology research 20090901

Title: Childhood mefloquine-induced mania and psychosis: a case report.

Journal: Journal of child neurology 20090801

Title: Mefloquine: interstitial pneumonia: rare events.

Journal: Prescrire international 20090801

Title: Artemisinin resistance in Plasmodium falciparum malaria.

Journal: The New England journal of medicine 20090730

Title: Mixed Plasmodium falciparum and Plasmodium vivax malaria in orthotopic liver transplant recipient.

Journal: Transplantation 20090727

Title: [Malaria--current diagnosis and therapy].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20090715

Title: Artemisinin-based combination therapy for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20090708

Title: Dose-response relationships and tegumental surface alterations in Opisthorchis viverrini following treatment with mefloquine in vivo and in vitro.

Journal: Parasitology research 20090701

Title: Case 4-2009: a pregnant woman with fever after a trip to Africa.

Journal: The New England journal of medicine 20090604

Title: Histopathological changes in adult Schistosoma japonicum harbored in mice treated with a single dose of mefloquine.

Journal: Parasitology research 20090601

Title: Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.

Journal: The Korean journal of parasitology 20090601

Title: MCC 'tardy' as couple suffer Mefliam 'nightmare'.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20090601

Title: [Therapeutic efficacy of a regimen of artesunate-mefloquine-primaquine treatment for Plasmodium falciparum malaria and treatment effects on gametocytic development].

Journal: Biomedica : revista del Instituto Nacional de Salud 20090601

Title: Pannexin 1: the molecular substrate of astrocyte 'hemichannels'.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527

Title: Two-step liquid-phase microextraction and high-performance liquid chromatography for the simultaneous analysis of the enantiomers of mefloquine and its main metabolite carboxymefloquine in plasma.

Journal: Analytical and bioanalytical chemistry 20090301

Title: Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.

Journal: Journal of medicinal chemistry 20090226

Title: Influence of chitosan crosslinking on bitterness of mefloquine hydrochloride microparticles using central composite design.

Journal: Journal of pharmaceutical sciences 20090201

Title: Mefloquine--an aminoalcohol with promising antischistosomal properties in mice.

Journal: PLoS neglected tropical diseases 20090101

Title: Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia.

Journal: Malaria journal 20090101

Title: Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia.

Journal: Malaria journal 20090101

Title: Swedish traveller with Plasmodium knowlesi malaria after visiting Malaysian Borneo.

Journal: Malaria journal 20090101

Title: Mefloquine neurotoxicity: a literature review.

Journal: Travel medicine and infectious disease 20090101

Title: Evaluation of mood profiles during malaria chemoprophylaxis: a randomized, double-blind, four-arm study.

Journal: Journal of travel medicine 20090101

Title: Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment.

Journal: PloS one 20090101

Title: Impact of cerebral malaria on brain distribution of mefloquine.

Journal: Drug metabolism letters 20090101

Title: Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria.

Journal: Malaria journal 20090101

Title: Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans.

Journal: BMC genomics 20090101

Title: Epileptogenic potential of mefloquine chemoprophylaxis: a pathogenic hypothesis.

Journal: Malaria journal 20090101

Title: The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria.

Journal: Malaria journal 20090101

Title: Analysis of the direct and indirect costs of treatment of imported malaria in the Slovak Republic.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20090101

Title: Travel health care for immigrant children visiting friends and relatives abroad: retrospective analysis of a hospital-based travel health service in a US urban underserved area.

Journal: Journal of travel medicine 20090101

Title: Post-malaria neurological syndrome: a case report and review of the literature.

Journal: Journal of travel medicine 20090101

Title: Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children.

Journal: Malaria journal 20090101

Title: [Case report: two imported Plasmodium falciparum cases].

Journal: Turkiye parazitolojii dergisi 20090101

Title: Modafinil increases arousal determined by P13 potential amplitude: an effect blocked by gap junction antagonists.

Journal: Sleep 20081201

Title: Well-tolerated chemoprophylaxis uniformly prevented Swedish soldiers from Plasmodium falciparum malaria in Liberia, 2004-2006.

Journal: Military medicine 20081201

Title: Blockade by mefloquine of intercellular electrical coupling between vascular endothelial cells in the guinea-pig mesenteric arteries.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20081201

Title: Elevated pressure triggers a physiological release of ATP from the retina: Possible role for pannexin hemichannels.

Journal: Neuroscience 20081119

Title: Lack of multiple copies of pfmdr1 gene in Papua New Guinea.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101

Title: A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.

Journal: The American journal of tropical medicine and hygiene 20081101

Title: Drugs for treating uncomplicated malaria in pregnant women.

Journal: The Cochrane database of systematic reviews 20081008

Title: Molecular surveillance for multidrug-resistant Plasmodium falciparum, Cambodia.

Journal: Emerging infectious diseases 20081001

Title: [Cerebral malaria in a pregnant woman].

Journal: Medicina intensiva 20081001

Title: Protection of retinal cells from ischemia by a novel gap junction inhibitor.

Journal: Biochemical and biophysical research communications 20080905

Title: P2X7 receptor-Pannexin1 complex: pharmacology and signaling.

Journal: American journal of physiology. Cell physiology 20080901

Title: Effect of artemisinins and amino alcohol partner antimalarials on mammalian sarcoendoplasmic reticulum calcium adenosine triphosphatase activity.

Journal: Basic & clinical pharmacology & toxicology 20080901

Title: Schistosomicidal activity of the antimalarial drug, mefloquine, in Schistosoma mansoni-infected mice.

Journal: Travel medicine and infectious disease 20080901

Title: Clinical practice. Malaria prevention in short-term travelers.

Journal: The New England journal of medicine 20080807

Title: Neuronal coupling via connexin36 contributes to spontaneous synaptic currents of striatal medium-sized spiny neurons.

Journal: Journal of neuroscience research 20080801

Title: Artemisinin derivatives and malaria: useful, in combination with other antimalarials.

Journal: Prescrire international 20080801

Title: Mixed tetraoxanes containing the acetone subunit as antimalarials.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Design and optimization of mefloquine hydrochloride microparticles for bitter taste masking.

Journal: AAPS PharmSciTech 20080601

Title: Gametocyte clearance in uncomplicated and severe Plasmodium falciparum malaria after artesunate-mefloquine treatment in Thailand.

Journal: The Korean journal of parasitology 20080601

Title: Psychotic mania associated with mefloquine in a bipolar patient.

Journal: Southern medical journal 20080501

Title: Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border.

Journal: Emerging infectious diseases 20080501

Title: A woman from Honduras with a painful forearm and fever.

Journal: The American journal of tropical medicine and hygiene 20080501

Title: New combined pill to treat malaria is launched.

Journal: BMJ (Clinical research ed.) 20080419

Title: Liquid-phase microextraction combined with high-performance liquid chromatography for the enantioselective analysis of mefloquine in plasma samples.

Journal: Journal of pharmaceutical and biomedical analysis 20080414

Title: Antimalarial drugs inhibit human 5-HT(3) and GABA(A) but not GABA(C) receptors.

Journal: British journal of pharmacology 20080401

Title: Studies on antimalarial drug susceptibility in Colombia, in relation to Pfmdr1 and Pfcrt.

Journal: Parasitology 20080401

Title: [Tolerance and efficacy of mefloquine as the first line treatment of uncomplicated P. falciparum malaria in children].

Journal: Pathologie-biologie 20080201

Title: Hyper-reactive malarial splenomegaly in a patient with human immunodeficiency virus.

Journal: The American journal of tropical medicine and hygiene 20080201

Title: Prolonged Plasmodium falciparum infection in immigrants, Paris.

Journal: Emerging infectious diseases 20080201

Title: WITHDRAWN: Mefloquine for preventing malaria in non-immune adult travellers.

Journal: The Cochrane database of systematic reviews 20080123

Title: Clinical inquiries. What is the most effective and safe malaria prophylaxis during pregnancy?

Journal: The Journal of family practice 20080101

Title: Prevalence of contraindications to mefloquine use among USA military personnel deployed to Afghanistan.

Journal: Malaria journal 20080101

Title: Clinically uncomplicated Plasmodium falciparum malaria with high schizontaemia: a case report.

Journal: Malaria journal 20080101

Title: Cost of increasing access to artemisinin combination therapy: the Cambodian experience.

Journal: Malaria journal 20080101

Title: Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20080101

Title: Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria.

Journal: Malaria journal 20080101

Title: Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand.

Journal: Malaria journal 20080101

Title: Trends in antimalarial prescriptions in Australia 2002 to 2005.

Journal: Journal of travel medicine 20080101

Title: Mefloquine-induced eosinophilic pneumonia.

Journal: Pharmacotherapy 20071201

Title: Inadequate chemoprophylaxis and the risk of malaria.

Journal: Australian family physician 20071201

Title: Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.

Journal: The American journal of tropical medicine and hygiene 20071201

Title: Malaria chemoprophylaxis: what do the travelers choose, and how does pretravel consultation influence their final decision.

Journal: The American journal of tropical medicine and hygiene 20071201

Title: Malaria in Egypt, Saudi Arabia and Yemen: a clinical pilot study.

Journal: Journal of the Egyptian Society of Parasitology 20071201

Title: Selective ambulatory management of Plasmodium falciparum malaria in paediatric refugees.

Journal: Archives of disease in childhood 20071101

Title: Design, synthesis, and pharmacological evaluation of mefloquine-based ligands as novel antituberculosis agents.

Journal: ChemMedChem 20071101

Title: Pharmacokinetics of two paediatric artesunate mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon.

Journal: The Journal of antimicrobial chemotherapy 20071101

Title: Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.

Journal: Clinical pharmacology and therapeutics 20071101

Title: Clinical inquiries. When should travelers begin malaria prophylaxis?

Journal: The Journal of family practice 20071101

Title: Reversible hearing loss in temporal association with chemoprophylactic mefloquine use.

Journal: Travel medicine and infectious disease 20071101

Title: Study on the biochemical basis of mefloquine resistant Plasmodium falciparum.

Journal: Experimental parasitology 20071001

Title: An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological studies of the drug combination.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071001

Title: Self-reported adverse events associated with antimalarial chemoprophylaxis in peace corps volunteers.

Journal: American journal of preventive medicine 20070901

Title: Mefloquine versus 3-day oral quinine-clindamycin in uncomplicated imported falciparum malaria.

Journal: Travel medicine and infectious disease 20070901

Title: Lariam and Halfan.

Journal: Journal of the Royal Society of Medicine 20070801

Title: Adaptation of a multi-drug resistant strain of Plasmodium falciparum from Peru to Aotus lemurinus griseimembra, A. nancymaae, and A. vociferans monkeys.

Journal: The American journal of tropical medicine and hygiene 20070801

Title: Anemia and antibodies to the 19-kDa fragment of MSP1 during Plasmodium falciparum infection in Aotus monkeys.

Journal: Comparative medicine 20070801

Title: A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds.

Journal: Experimental parasitology 20070701

Title: Effect of Plasmodium yoelii nigeriensis infection on hepatic and splenic glutathione-S-transferase(s) in Swiss albino and db/+ mice: efficacy of mefloquine and menadione in antimalarial chemotherapy.

Journal: Parasitology 20070701

Title: The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors.

Journal: British journal of pharmacology 20070701

Title: The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs.

Journal: Annals of tropical medicine and parasitology 20070701

Title: Dramatically decreased therapeutic efficacy of chloroquine and sulfadoxine-pyrimethamine, but not mefloquine, in southern Benin.

Journal: Tropical medicine & international health : TM & IH 20070701

Title: Clinical efficacy of high dose monotherapy of oral dihydroartemisinin in uncomplicated falciparum malaria in viet nam.

Journal: Japanese journal of infectious diseases 20070701

Title: HTS, chemical hybridization, and drug design identify a chemically unique antituberculosis agent-coupling serendipity and rational approaches to drug discovery.

Journal: ChemMedChem 20070601

Title: Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains.

Journal: The American journal of tropical medicine and hygiene 20070601

Title: [Polymorphisms of the pfmdr1 gene in field samples of Plasmodium falciparum and their association with therapeutic response to antimalarial drugs and severe malaria in Colombia].

Journal: Biomedica : revista del Instituto Nacional de Salud 20070601

Title: Controversies and misconceptions in malaria chemoprophylaxis for travelers.

Journal: JAMA 20070523

Title: Behavioral synergism between D(1) and D(2) dopamine receptors in mice does not depend on gap junctions.

Journal: Synapse (New York, N.Y.) 20070501

Title: Roxithromycin potentiates the effects of chloroquine and mefloquine on multidrug-resistant Plasmodium falciparum in vitro.

Journal: Experimental parasitology 20070401

Title: A lesson learnt: the rise and fall of Lariam and Halfan.

Journal: Journal of the Royal Society of Medicine 20070401

Title: Pfmdr1 and in vivo resistance to artesunate-mefloquine in falciparum malaria on the Cambodian-Thai border.

Journal: The American journal of tropical medicine and hygiene 20070401

Title: Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin.

Journal: European journal of pharmacology 20070308

Title: Raman spectroscopic investigation of the antimalarial agent mefloquine.

Journal: Analytical and bioanalytical chemistry 20070301

Title: Population pharmacokinetics of mefloquine in military personnel for prophylaxis against malaria infection during field deployment.

Journal: European journal of clinical pharmacology 20070301

Title: Comparative study of the effectiveness and pharmacokinetics of two rectal artesunate/oral mefloquine combination regimens for the treatment of uncomplicated childhood falciparum malaria.

Journal: Annals of tropical paediatrics 20070301

Title: Pharmacokinetics of mefloquine with dihydroartemisinin as 2-day regimens in patients with uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20070301

Title: Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

Journal: Molecular biology and evolution 20070201

Title: American Society of Tropical Medicine and Hygiene--55th Annual Meeting. 12-16 November 2006, Atlanta, GA, USA.

Journal: IDrugs : the investigational drugs journal 20070201

Title: Current malaria status and distribution of drug resistance in East and Southeast Asia with special focus to Thailand.

Journal: The Tohoku journal of experimental medicine 20070201

Title: Mefloquine treatment for uncomplicated falciparum malaria in young children 6-24 months of age in northern Ghana.

Journal: The American journal of tropical medicine and hygiene 20070201

Title: In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).

Journal: The American journal of tropical medicine and hygiene 20070201

Title: A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.

Journal: Tropical medicine & international health : TM & IH 20070201

Title: [Acute hepatitis associated with mefloquine therapy].

Journal: Gastroenterologia y hepatologia 20070201

Title: Maculopathy associated with mefloquine (Lariam) therapy for malaria prophylaxis.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20070201

Title: Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach.

Journal: Malaria journal 20070101

Title: The safety and tolerance of atovaquone/proguanil for the long-term prophylaxis of plasmodium falciparum malaria in non-immune travelers and expatriates [corrected].

Journal: Journal of travel medicine 20070101

Title: Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal.

Journal: Malaria journal 20070101

Title: DNA cleavage induced by photoexcited antimalarial drugs: a photophysical and photobiological study.

Journal: Photochemistry and photobiology 20070101

Title: Malaria and mefloquine prophylaxis use among Japan Ground Self-Defense Force personnel deployed in East Timor.

Journal: Journal of travel medicine 20070101

Title: Screening of gap junction antagonists on dye coupling in the rabbit retina.

Journal: Visual neuroscience 20070101

Title: A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru.

Journal: PloS one 20070101

Title: Susceptibility to chloroquine, mefloquine and artemisinin of Plasmodium vivax in northwestern Thailand.

Journal: Wiener klinische Wochenschrift 20070101

Title: Relapsing vivax malaria after 6 months of daily atovaquone/proguanil in Afghanistan: the case for expanded use of primaquine as a causal prophylactic.

Journal: Journal of travel medicine 20070101

Title: The prevalence and degree of resistance of Plasmodium falciparum to first-line antimalarial drugs: an in vitro study from a malaria endemic region in Yemen.

Journal: Annals of Saudi medicine 20070101

Title: Effect of mefloquine on the mechanical activity of the mouse isolated rectal smooth muscle.

Journal: Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20070101

Title: The connexin 36 blockers quinine, quinidine and mefloquine inhibit cortical spreading depression in a rat neocortical slice model in vitro.

Journal: Brain research bulletin 20061211

Title: Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia.

Journal: Tropical medicine & international health : TM & IH 20061201

Title: In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

Journal: Tropical medicine & international health : TM & IH 20061201

Title: An open label randomized comparison of mefloquine-artesunate as separate tablets vs. a new co-formulated combination for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.

Journal: Tropical medicine & international health : TM & IH 20061101

Title: Carbenoxolone and mefloquine suppress tremor in the harmaline mouse model of essential tremor.

Journal: Movement disorders : official journal of the Movement Disorder Society 20061001

Title: Plasmodium falciparum malaria associated with mefloquine failure in Gambia.

Journal: Pharmacotherapy 20061001

Title: MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine.

Journal: Clinical pharmacology and therapeutics 20061001

Title: Fluoxetine potentiates chloroquine and mefloquine effect on multidrug-resistant Plasmodium falciparum in vitro.

Journal: Japanese journal of infectious diseases 20061001

Title: Interaction studies of omeprazole with mefloquine, pyrimethamine and sulfadoxine.

Journal: Pakistan journal of pharmaceutical sciences 20061001

Title: Efficacy and safety of atovaquone-proguanil compared with mefloquine in the treatment of nonimmune patients with uncomplicated P. falciparum malaria in Japan.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20061001

Title: [A plasmodium alciparum malaria case originated from Mozambique: clues for the diagnosis and therapy].

Journal: Mikrobiyoloji bulteni 20061001

Title: Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia.

Journal: Tropical medicine & international health : TM & IH 20060901

Title: An unusual cutaneous manifestation with mefloquine.

Journal: The American journal of emergency medicine 20060901

Title: Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.

Journal: The Journal of infectious diseases 20060815

Title: An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).

Journal: Tropical medicine & international health : TM & IH 20060801

Title: An in vivo test to assess mefloquine 25 mg/kg for the treatment of uncomplicated falciparum malaria in Rondônia, Brazil.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20060801

Title: Connexin-36 gap junctions mediate electrical coupling between ventral tegmental area GABA neurons.

Journal: Synapse (New York, N.Y.) 20060701

Title: Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance.

Journal: Cellular and molecular life sciences : CMLS 20060701

Title: Artemisinin combination therapies.

Journal: Lancet (London, England) 20060624

Title: Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.

Journal: Lancet (London, England) 20060624

Title: Mefloquine toxicity presenting with polyneuropathy - a report of two cases in India.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20060601

Title: Mefloquine enhances nigral gamma-aminobutyric acid release via inhibition of cholinesterase.

Journal: The Journal of pharmacology and experimental therapeutics 20060601

Title: Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative.

Journal: PLoS medicine 20060601

Title: Mefloquine-induced mania in a 22-year-old Chinese man.

Journal: Singapore medical journal 20060601

Title: In vitro study assessing the response of plasmodium falciparum malaria to chloroquine, sulfadoxine/pyrimethamine, quinine and mefloquine in Wad Medani District, Sudan.

Journal: Saudi medical journal 20060601

Title: Design, synthesis, and SAR studies of mefloquine-based ligands as potential antituberculosis agents.

Journal: ChemMedChem 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Mefloquine use and hospitalizations among US service members, 2002-2004.

Journal: The American journal of tropical medicine and hygiene 20060501

Title: [Relapse of Plasmodium falciparum malaria in a patient treated with artesunate].

Journal: Medecine et maladies infectieuses 20060501

Title: [Spectacular suicide associated with mefloquine].

Journal: Presse medicale (Paris, France : 1983) 20060501

Title: [Atypical course of falciparum malaria in an asplenic patient].

Journal: Presse medicale (Paris, France : 1983) 20060501

Title: Malaria. 'One step forward, two steps back'.

Journal: East African medical journal 20060501

Title: Efficacy and safety of an artesunate/mefloquine combination, (artequin) in the treatment of uncomplicated P. falciparum malaria in Kenya.

Journal: East African medical journal 20060501

Title: Mefloquine is highly efficacious against chloroquine-resistant Plasmodium vivax malaria and Plasmodium falciparum malaria in Papua, Indonesia.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415

Title: Emerging chloroquine-resistant Plasmodium vivax (Benign Tertian) malaria: the need for alternative drug treatment.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060415

Title: Predictors of the failure of treatment with pyrimethamine-sulfadoxine in children with uncomplicated falciparum malaria.

Journal: Acta tropica 20060401

Title: Mefloquine.

Journal: Nursing times 20060401

Title: Mefloquine selectively increases asynchronous acetylcholine release from motor nerve terminals.

Journal: Neuropharmacology 20060301

Title: Stimulation of choline/Mg2+ antiport in rat erythrocytes by mefloquine.

Journal: Magnesium research 20060301

Title: [Coartem and fansimef in the treatment of falciparum malaria].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20060227

Title: Conformation stability and organization of mefloquine molecules in different environments.

Journal: Bioorganic & medicinal chemistry letters 20060215

Title: A randomized trial comparing the efficacy of four treatment regimens for uncomplicated falciparum malaria in Assam state, India.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20060201

Title: In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

Journal: Tropical medicine & international health : TM & IH 20060201

Title: Thrombotic-thrombocytopenic purpura following malaria prophylaxis with mefloquine.

Journal: The Journal of antimicrobial chemotherapy 20060101

Title: Methodological concerns regarding the relation between mefloquine and serious psychiatric events in females.

Journal: The Journal of clinical psychiatry 20060101

Title: Successful treatment of imported cerebral malaria with artesunate-mefloquine combination therapy.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20060101

Title: [Cytochrome P-450 and the response to antimalarial drugs].

Journal: Revista panamericana de salud publica = Pan American journal of public health 20060101

Title: Acute respiratory distress syndrome in Plasmodium vivax malaria in traveler returning from Venezuela.

Journal: Journal of travel medicine 20060101

Title: Mefloquine-induced pneumonitis.

Journal: Journal of travel medicine 20060101

Title: [Improvement of epidemiological surveillance of malaria among frontier guards in Tadjukistan].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20060101

Title: Drug interactions and pharmacogenetic reactions are the basis for chloroquine and mefloquine-induced psychosis.

Journal: Medical hypotheses 20060101

Title: Psychosis with paranoid delusions after a therapeutic dose of mefloquine: a case report.

Journal: Malaria journal 20060101

Title: [Severe imported malaria. The experience of the military hospital of Marrakech].

Journal: Annales de biologie clinique 20060101

Title: Quinoline-resistance reversing agents for the malaria parasite Plasmodium falciparum.

Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20060101

Title: Mefloquine effects on the lens suggest cooperative gating of gap junction channels.

Journal: The Journal of membrane biology 20060101

Title: [Severe imported malaria: the experience of the Avicenna military hospital of Marrakech].

Journal: Sante (Montrouge, France) 20060101

Title: Chemoprophylaxis according to the guidelines on malaria prevention for Japanese overseas travelers.

Journal: The Southeast Asian journal of tropical medicine and public health 20060101

Title: Are we losing artemisinin combination therapy already?

Journal: Lancet (London, England) 20051203

Title: Mefloquine inhibits cholinesterases at the mouse neuromuscular junction.

Journal: Neuropharmacology 20051201

Title: Fatty food does not alter blood mefloquine concentrations in the treatment of falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20051201

Title: Malaria: prevention in travellers.

Journal: Clinical evidence 20051201

Title: Amplification of Plasmodium falciparum multidrug resistance gene 1 in isolates from Gabon.

Journal: The Journal of infectious diseases 20051115

Title: Transcriptional profiling of mefloquine-induced disruption of calcium homeostasis in neurons in vitro.

Journal: Genomics 20051101

Title: [Ineffective change of antimalaria prophylaxis to Artemisia vulgaris in a group travelling to West Africa].

Journal: Ugeskrift for laeger 20051024

Title: Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20051019

Title: [Malaria chemoprophylaxis].

Journal: Ugeskrift for laeger 20051017

Title: [Malaria prophylaxis for long-term travellers and expatriates].

Journal: Ugeskrift for laeger 20051017

Title: [Painless jaundice after holidays in Tanzania].

Journal: Der Internist 20051001

Title: Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20051001

Title: The efficacy and tolerability of doxycycline and mefloquine in malaria prophylaxis of the ISAF troops in Afghanistan.

Journal: The Journal of infection 20051001

Title: In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Malaria in an eastern screech owl (Otus asio).

Journal: Avian diseases 20050901

Title: An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20050901

Title: Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes.

Journal: Biochemical pharmacology 20050815

Title: A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050815

Title: First-time diagnosis of severe depression: induced by mefloquine?

Journal: Journal of clinical psychopharmacology 20050801

Title: Molecular epidemiology of drug resistance markers of Plasmodium falciparum malaria in Thailand.

Journal: Tropical medicine & international health : TM & IH 20050801

Title: pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum.

Journal: Molecular microbiology 20050801

Title: Questionnaire-based analysis of mefloquine chemoprophylaxis for malaria in a Japanese population.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20050801

Title: Effectiveness of antimalarial drugs.

Journal: The New England journal of medicine 20050728

Title: Drugs for treating uncomplicated malaria in pregnant women.

Journal: The Cochrane database of systematic reviews 20050720

Title: Gamma-aminobutyric acid and mefloquine-induced seizures in mice.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20050701

Title: Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20050601

Title: Malaria: uncomplicated, caused by Plasmodium falciparum.

Journal: Clinical evidence 20050601

Title: ATPase activity of purified plasma membranes and digestive vacuoles from Plasmodium falciparum.

Journal: Molecular and biochemical parasitology 20050501

Title: pfmdr1 genotyping and in vivo mefloquine resistance on the Thai-Myanmar border.

Journal: The American journal of tropical medicine and hygiene 20050501

Title: Mefloquine resistance reversal action of ketoconazole - a cytochrome P450 inhibitor, against mefloquine-resistant malaria.

Journal: Parasitology 20050501

Title: An open, randomized trial of three-day treatment with artesunate combined with a standard dose of mefloquine divided over either two or three days, for acute, uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20050501

Title: Life-saving rectal artesunate for complicated malaria in children.

Journal: The Southeast Asian journal of tropical medicine and public health 20050501

Title: Effectiveness of antimalarial drugs.

Journal: The New England journal of medicine 20050414

Title: Design, synthesis and antimalarial activity of trifluoromethylartemisinin-mefloquine dual molecules.

Journal: Chembiochem : a European journal of chemical biology 20050401

Title: [Mefloquine versus halofantrine in children suffering from acute uncomplicated falciparum malaria].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20050401

Title: [Relative bioavailability of an optimised galenical formulation of mefloquine].

Journal: Praxis 20050330

Title: [Relapse of Plasmodium malariae malaria 20 years after living in an endemic area].

Journal: Presse medicale (Paris, France : 1983) 20050312

Title: Absence of nucleotide polymorphism in a Plasmodium vivax multidrug resistance gene after failure of mefloquine prophylaxis in French Guyana.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20050301

Title: Efficacies of mefloquine alone and of artesunate followed by mefloquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.

Journal: Annals of tropical medicine and parasitology 20050301

Title: Mefloquine and doxycycline malaria prophylaxis in Australian soldiers in East Timor.

Journal: The Medical journal of Australia 20050221

Title: Efficacy of antimalarial chemoprophylaxis among French residents travelling to Africa.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20050201

Title: Identification of putative Plasmodium falciparum mefloquine resistance genes.

Journal: Molecular and biochemical parasitology 20050201

Title: A malaria outbreak following a British military deployment to Sierra Leone.

Journal: The Journal of infection 20050201

Title: Mefloquine increases the risk of serious psychiatric events during travel abroad: a nationwide case-control study in the Netherlands.

Journal: The Journal of clinical psychiatry 20050201

Title: [Case of drug-induced pneumonia possibly due to mefloquine (antimalarial drug)].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20050201

Title: [Neuropsychiatric symptoms caused by mefloquine (report of several cases)].

Journal: Orvosi hetilap 20050116

Title: In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002.

Journal: Acta tropica 20050101

Title: Syndromic management of prolonged fever: a cost-effective approach.

Journal: Tropical doctor 20050101

Title: Pharmacokinetics of the four combination regimens of dihydroartemisinin/mefloquine in acute uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20050101

Title: Investigation of bioavailability, pharmacokinetics and safety of new pediatric formulations of artesunate and mefloquine.

Journal: The Southeast Asian journal of tropical medicine and public health 20050101

Title: Pharmacodynamic analysis of antimalarials used in Plasmodium falciparum imported malaria in northern Italy.

Journal: Journal of travel medicine 20050101

Title: In vitro antimalarial drug susceptibility in Thai border areas from 1998-2003.

Journal: Malaria journal 20050101

Title: A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand.

Journal: Malaria journal 20050101

Title: Antimalarial multi-drug resistance in Asia: mechanisms and assessment.

Journal: Current topics in microbiology and immunology 20050101

Title: In vitro susceptibility and genetic variations for chloroquine and mefloquine in Plasmodium falciparum isolates from Thai-Myanmar border.

Journal: The Southeast Asian journal of tropical medicine and public health 20050101

Title: Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross-sectional survey on the prevalence of fake antimalarials.

Journal: Tropical medicine & international health : TM & IH 20041201

Title: Malaria: prevention in travellers.

Journal: Clinical evidence 20041201

Title: Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.

Journal: The Journal of infectious diseases 20041115

Title: Australian army faces legal action over mefloquine.

Journal: BMJ (Clinical research ed.) 20041106

Title: Therapeutic efficacy of artemether-lumefantrine and artesunate-mefloquine for treatment of uncomplicated Plasmodium falciparum malaria in Luang Namtha Province, Lao People's Democratic Republic.

Journal: Tropical medicine & international health : TM & IH 20041101

Title: Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar.

Journal: Tropical medicine & international health : TM & IH 20041101

Title: Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041015

Title: Mefloquine in the treatment of falciparum malaria during pregnancy in Eastern Sudan.

Journal: Saudi medical journal 20041001

Title: 'Serious' and 'severe' adverse drug reactions need defining.

Journal: BMJ (Clinical research ed.) 20040904

Title: The relationship between body weight and tolerance to mefloquine prophylaxis in non-immune adults: results of a questionnaire-based study.

Journal: Annals of tropical medicine and parasitology 20040901

Title: The sensitivities of yeast strains deficient in PDR ABC transporters, to quinoline-ring antimalarial drugs.

Journal: Annals of tropical medicine and parasitology 20040901

Title: SRI-286, a thiosemicarbazole, in combination with mefloquine and moxifloxacin for treatment of murine Mycobacterium avium complex disease.

Journal: Antimicrobial agents and chemotherapy 20040901

Title: Declining mefloquine sensitivity of Plasmodium falciparum along the Thai-Myanmar border.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Application of multi-component reactions to antimalarial drug discovery. Part 1: Parallel synthesis and antiplasmodial activity of new 4-aminoquinoline Ugi adducts.

Journal: Bioorganic & medicinal chemistry letters 20040802

Title: Artesunate with mefloquine at various intervals for non-severe Plasmodium falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20040801

Title: The antimalarial potential of 4-quinolinecarbinolamines may be limited due to neurotoxicity and cross-resistance in mefloquine-resistant Plasmodium falciparum strains.

Journal: Antimicrobial agents and chemotherapy 20040701

Title: Safety of mefloquine in infants with acute falciparum malaria.

Journal: The Pediatric infectious disease journal 20040701

Title: [Malaria: prophylaxis, treatment, stand-by medication. A single mosquito bite suffices].

Journal: MMW Fortschritte der Medizin 20040617

Title: Babesia microti infection in Europe.

Journal: Current microbiology 20040601

Title: The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum.

Journal: Annals of tropical medicine and parasitology 20040601

Title: [Combined antimalarial therapy using artemisinin].

Journal: Parassitologia 20040601

Title: Malaria: prevention in travellers.

Journal: Clinical evidence 20040601

Title: Mefloquine--its 20 years in the Thai Malaria Control Program.

Journal: The Southeast Asian journal of tropical medicine and public health 20040601

Title: Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.

Journal: Biochemistry 20040504

Title: Polymorphism of the Plasmodium falciparum multidrug resistance and chloroquine resistance transporter genes and in vitro susceptibility to aminoquinolines in isolates from the Peruvian Amazon.

Journal: The American journal of tropical medicine and hygiene 20040501

Title: Cerebral uptake of mefloquine enantiomers with and without the P-gp inhibitor elacridar (GF1210918) in mice.

Journal: British journal of pharmacology 20040401

Title: Low body mass index is associated with an increased risk of neuropsychiatric adverse events and concentration impairment in women on mefloquine.

Journal: British journal of clinical pharmacology 20040401

Title: Optimising operational use of artesunate-mefloquine: a randomised comparison of four treatment regimens.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20040301

Title: Genetic and biochemical aspects of drug resistance in malaria parasites.

Journal: Current drug targets. Infectious disorders 20040301

Title: Photophysical and photobiological behavior of antimalarial drugs in aqueous solutions.

Journal: Photochemistry and photobiology 20040301

Title: Artesunate combinations for malaria.

Journal: Lancet (London, England) 20040227

Title: A malaria outbreak following a British military deployment to Sierra Leone.

Journal: The Journal of infection 20040201

Title: Mefloquine for preventing malaria in nonimmune adult travelers.

Journal: American family physician 20040201

Title: Efficacy of mefloquine and mefloquine-artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon region of Bolivia.

Journal: Tropical medicine & international health : TM & IH 20040201

Title: Malaria during pregnancy in a reference centre from the Brazilian Amazon: unexpected increase in the frequency of Plasmodium falciparum infections.

Journal: Memorias do Instituto Oswaldo Cruz 20040201

Title: FDA requires warnings on anti-malaria drug Lariam.

Journal: Consumer reports 20040101

Title: Susceptibility of Plasmodium falciparum to the drugs used to treat severe malaria (quinine) and to prevent malaria (mefloquine, cycloguanil) in Comoros Union and Madagascar.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20040101

Title: [Cerebral Malaria in Ceará: a case report].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20040101

Title: Is quartan malaria safely prevented by mefloquine prophylaxis?

Journal: Journal of travel medicine 20040101

Title: The effect of mefloquine and volume-regulated anion channel inhibitors on induced transport in Plasmodium falciparum-infected human red blood cells.

Journal: Blood cells, molecules & diseases 20040101

Title: Drug-induced depression: a systematic review to inform clinical practice.

Journal: Psychotherapy and psychosomatics 20040101

Title: Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

Journal: Lancet (London, England) 20040101

Title: Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20040101

Title: Resistance reversal action of ketoconazole against mefloquine resistance of Plasmodium yoelii nigeriensis.

Journal: Experimental parasitology 20040101

Title: Long-term malaria prophylaxis for travelers.

Journal: Journal of travel medicine 20040101

Title: Comparative study of the in vitro sensitivity of Plasmodium falciparum to artemisinin in two border areas of Thailand.

Journal: Wiener klinische Wochenschrift 20040101

Title: In vitro sensitivity of Plasmodium falciparum to lumefantrine in north-western Thailand.

Journal: Wiener klinische Wochenschrift 20040101

Title: Impact of the national protocol for malaria treatment on prescribing patterns in Gezira state, Sudan.

Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20040101

Title: Genetic analysis of mefloquine-resistant mechanism of Plasmodium falciparum.

Journal: Nucleic acids symposium series (2004) 20040101

Title: Randomised efficacy and safety study of two 3-day artesunate rectal capsule/mefloquine regimens versus artesunate alone for uncomplicated malaria in Ecuadorian children.

Journal: Acta tropica 20031201

Title: Military aviators, special operations forces, and causal malaria prophylaxis.

Journal: Military medicine 20031201

Title: [Treatment of uncomplicated Plasmodium falciparum malaria in children: comparison of halofantrine with mefloquine].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20031201

Title: Malaria: prevention in travellers.

Journal: Clinical evidence 20031201

Title: Diagnosis and treatment of malaria in children.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031115

Title: Delayed onset of malaria--implications for chemoprophylaxis in travelers.

Journal: The New England journal of medicine 20031016

Title: [Mefloquine treatment in infants and children with Plasmodium falciparum malaria: an efficient and well tolerated treatment].

Journal: Pathologie-biologie 20031001

Title: Malaria in a cohort of Javanese migrants to Indonesian Papua.

Journal: Annals of tropical medicine and parasitology 20030901

Title: Atovaquone-proguanil for recrudescent Plasmodium falciparum in Vietnam.

Journal: Annals of tropical medicine and parasitology 20030901

Title: Malaria and children: the risks, precautions, and the nurse's role.

Journal: Professional nurse (London, England) 20030901

Title: A cost-effectiveness analysis of three antimalarial treatments for acute, uncomplicated Plasmodium falciparum malaria in Mumbai, India.

Journal: The Journal of the Association of Physicians of India 20030901

Title: Monitoring the therapeutic efficacy of antimalarials against uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: Six-years monitoring the efficacy of the combination of artesunate and mefloquine for the treatment of uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: In vitro susceptibility of Plasmodium falciparum isolates to chloroquine and mefloquine in southeastern Mindanao Island, the Philippines.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: [A randomized comparative study of naphtoquine, mefloquine and artsunate in the treatment of falciparum malaria].

Journal: Zhonghua yi xue za zhi 20030825

Title: Mapping of the Plasmodium falciparum multidrug resistance gene 5'-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites.

Journal: Molecular microbiology 20030801

Title: Postmalaria neurological syndrome after treatment of Plasmodium falciparum malaria in the United States.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030715

Title: Asymptomatic, recrudescent, chloroquine-resistant Plasmodium falciparum infections in Nigerian children: clinical and parasitological characteristics and implications for the transmission of drug-resistant parasites.

Journal: Annals of tropical medicine and parasitology 20030701

Title: Mefloquine, moxifloxacin, and ethambutol are a triple-drug alternative to macrolide-containing regimens for treatment of Mycobacterium avium disease.

Journal: The Journal of infectious diseases 20030615

Title: [Malaria--case report].

Journal: Deutsche medizinische Wochenschrift (1946) 20030606

Title: Failure of a chloroquine chemoprophylaxis program to adequately prevent malaria during pregnancy in Koupéla District, Burkina Faso.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030601

Title: Efficacy of mefloquine and a mefloquine-artesunate combination therapy for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon Basin of Peru.

Journal: The American journal of tropical medicine and hygiene 20030501

Title: The efficacy of combined mefloquine-artesunate versus mefloquine-primaquine on subsequent development of Plasmodium falciparum gametocytemia.

Journal: The American journal of tropical medicine and hygiene 20030501

Title: Enantioseparation of erythro-mefloquine and its analogues in capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20030424

Title: Prophylaxis failure due to probable mefloquine resistant P falciparum from Tanzania.

Journal: Acta tropica 20030401

Title: Malaria in Austria 1990-2000.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20030401

Title: The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines.

Journal: Annals of tropical medicine and parasitology 20030401

Title: [Convulsions and shock during antimalarial chemoprophylaxis with mefloquine].

Journal: Presse medicale (Paris, France : 1983) 20030308

Title: The clinical spectrum of severe imported falciparum malaria in the intensive care unit: report of 188 cases in adults.

Journal: American journal of respiratory and critical care medicine 20030301

Title: Ceramide mediates growth inhibition of the Plasmodium falciparum parasite.

Journal: Cellular and molecular life sciences : CMLS 20030301

Title: Treatment of imported uncomplicated malaria: a medical emergency.

Journal: Prescrire international 20030201

Title: Drug-resistant malaria in Bangladesh: an in vitro assessment.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: Descriptive study on the efficacy and safety of artesunate suppository in combination with other antimalarials in the treatment of severe malaria in Sudan.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: Utilisation of malaria prophylaxis: the effect of changes in guidelines in The Netherlands, 1993-1998.

Journal: Pharmacy world & science : PWS 20030201

Title: [Antiprotozoal drugs].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030201

Title: In vitro activity of chloroquine, quinine, mefloquine and halofantrine against Gabonese isolates of Plasmodium falciparum.

Journal: Tropical medicine & international health : TM & IH 20030101

Title: Lack of prediction of mefloquine and mefloquine-artesunate treatment outcome by mutations in the Plasmodium falciparum multidrug resistance 1 (pfmdr1) gene for P. falciparum malaria in Peru.

Journal: The American journal of tropical medicine and hygiene 20030101

Title: Efficacy of chloroquine, sulfadoxine-pyrimethamine, and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria on the north coast of Peru.

Journal: The American journal of tropical medicine and hygiene 20030101

Title: Effect of sample size and P-value filtering techniques on the detection of transcriptional changes induced in rat neuroblastoma (NG108) cells by mefloquine.

Journal: Malaria journal 20030101

Title: The efficacy of chemoprophylaxis against malaria with chloroquine plus proguanil, mefloquine, and atovaquone plus proguanil in travelers from Denmark.

Journal: Journal of travel medicine 20030101

Title: Trends in antimalarial drugs prescribed in Australia 1992 to 1998.

Journal: Journal of travel medicine 20030101

Title: Mefloquine and anticoagulant interaction.

Journal: Journal of travel medicine 20030101

Title: Trends in antimalarial drugs prescribed in New Zealand 1993 to 1998.

Journal: Journal of travel medicine 20030101

Title: [Efficacy and tolerance of mefloquine in the treatment of infants and children with Plasmodium falciparum malaria].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20030101

Title: Curses, madness, and mefloquine.

Journal: Psychosomatics 20030101

Title: The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro.

Journal: Malaria journal 20030101

Title: [Mefloquine resistance in Plasmodium falciparum malaria].

Journal: Recenti progressi in medicina 20030101

Title: Antimosquito precautions and medical chemoprophylaxis in French children with malaria.

Journal: Journal of travel medicine 20030101

Title: Evaluation of malaria chemoprophylaxis in Bahrain.

Journal: Journal of travel medicine 20030101

Title: Consumer guide for malaria drug.

Journal: FDA consumer 20030101

Title: Effects of mefloquine usage on genetic polymorphism of Plasmodium falciparum in Thai-Myanmarese border.

Journal: The Kobe journal of medical sciences 20030101

Title: Discovery of novel targets of quinoline drugs in the human purine binding proteome.

Journal: Molecular pharmacology 20021201

Title: In vitro sensitivity of Plasmodium falciparum to amodiaquine compared with other major antimalarials in Madagascar.

Journal: Parassitologia 20021201

Title: Mefloquine: contraindicated in patients with mood, psychotic or seizure disorders.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20021112

Title: Haem polymerase as a novel target of antimalarial action of cyproheptadine.

Journal: Biochemical pharmacology 20021101

Title: Drug-resistant Plasmodium falciparum infection in immigrants and non-immune travellers.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20021101

Title: Pancytopenia resulting from hemophagocytosis in malaria.

Journal: The Pediatric infectious disease journal 20021101

Title: Artesunate and mefloquine given simultaneously for three days via a prepacked blister is equally effective and tolerated as a standard sequential treatment of uncomplicated acute Plasmodium falciparum malaria: randomized, double-blind study in Thailand.

Journal: The American journal of tropical medicine and hygiene 20021101

Title: Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.

Journal: Science (New York, N.Y.) 20021004

Title: Atovaquone + proguanil: new preparation. Second-line antimalarial combination.

Journal: Prescrire international 20021001

Title: Synthesis and biological evaluation of new imidazo[1,2-a]pyridine derivatives designed as mefloquine analogues.

Journal: Farmaco (Societa chimica italiana : 1989) 20021001

Title: Use of nested PCR for differential diagnosis of falciparum malaria reinfection and relapse in drug-resistant patients.

Journal: Bulletin of experimental biology and medicine 20021001

Title: [Blackwater fever].

Journal: Presse medicale (Paris, France : 1983) 20020907

Title: Atovaquone plus chloroguanide versus mefloquine for malaria prophylaxis: a focus on neuropsychiatric adverse events.

Journal: Clinical pharmacology and therapeutics 20020901

Title: Mefloquine-induced paranoid psychosis and subsequent major depression in a 25-year-old student.

Journal: Pharmacopsychiatry 20020901

Title: Neuropsychiatric events during prophylactic use of mefloquine before travelling.

Journal: European journal of clinical pharmacology 20020901

Title: Clinical practice: antimalarial prophylaxis in patients with epilepsy [corrected].

Journal: Epilepsy research 20020901

Title: [Malaria of native Africans after returning home from European residence].

Journal: Orvosi hetilap 20020901

Title: An open randomized clinical trial of Artecom vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20020901

Title: A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20020901

Title: Impact of microscopy error on estimates of protective efficacy in malaria-prevention trials.

Journal: The Journal of infectious diseases 20020815

Title: Population pharmacokinetic and pharmacodynamic modelling of artemisinin and mefloquine enantiomers in patients with falciparum malaria.

Journal: European journal of clinical pharmacology 20020801

Title: [Senegal and malaria. True prophylactic failure of mefloquine].

Journal: Presse medicale (Paris, France : 1983) 20020713

Title: Profile and evolution of the chemosusceptibility of falciparum malaria imported into France in 2000.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20020701

Title: [Many travellers suffer of side-effects of malaria prophylaxis].

Journal: Lakartidningen 20020627

Title: Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.

Journal: Journal of medicinal chemistry 20020620

Title: Resistant malaria in a neonate.

Journal: Indian pediatrics 20020601

Title: Anemia in parasite- and recombinant protein-immunized aotus monkeys infected with Plasmodium falciparum.

Journal: The American journal of tropical medicine and hygiene 20020601

Title: Tolerability of antimalaria drugs.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020501

Title: Relationships between mefloquine blood levels, gender, and adverse reactions.

Journal: The American journal of tropical medicine and hygiene 20020501

Title: Relationships between mefloquine blood levels, gender, and adverse reactions.

Journal: The American journal of tropical medicine and hygiene 20020501

Title: In-vitro sensitivity of Plasmodium falciparum to chloroquine, halofantrine, mefloquine and quinine in Madagascar.

Journal: East African medical journal 20020501

Title: Safety evaluation of the drugs available to prevent malaria.

Journal: Expert opinion on drug safety 20020501

Title: Treatment of imported malaria in an ambulatory setting: prospective study.

Journal: BMJ (Clinical research ed.) 20020413

Title: Role of chiral chromatography in therapeutic drug monitoring and in clinical and forensic toxicology.

Journal: Therapeutic drug monitoring 20020401

Title: Efficacy of scopadulcic acid A against Plasmodium falciparum in vitro.

Journal: Journal of natural products 20020401

Title: Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine.

Journal: The Journal of infection 20020401

Title: A rapid spectrophotometric method for the determination of mefloquine hydrochloride.

Journal: Journal of pharmaceutical and biomedical analysis 20020301

Title: Lariam's legacy.

Journal: Consumer reports 20020301

Title: The influence of body weight on the pharmacokinetics of mefloquine.

Journal: British journal of clinical pharmacology 20020301

Title: An outbreak of cutaneous leishmaniasis among soldiers in Belém, Pará State, Brazil, caused by Leishmania (Viannia) lindenbergi n. sp. A new leishmanial parasite of man in the Amazon region.

Journal: Parasite (Paris, France) 20020301

Title: Malaria remains a military medical problem--MJ World. Published in Vol 147, Number 3, October 2001.

Journal: Journal of the Royal Army Medical Corps 20020301

Title: Unexpected frequency, duration and spectrum of adverse events after therapeutic dose of mefloquine in healthy adults.

Journal: Acta tropica 20020201

Title: Does mefloquine prophylaxis affect electroencephalographic patterns?

Journal: The American journal of medicine 20020201

Title: Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes.

Journal: Biochemical pharmacology 20020201

Title: Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine.

Journal: Parasitology 20020101

Title: Adverse effects of the antimalaria drug, mefloquine: due to primary liver damage with secondary thyroid involvement?

Journal: BMC public health 20020101

Title: Malaria recurrence caused by Plasmodium falciparum.

Journal: The Journal of the American Board of Family Practice 20020101

Title: Fever, anemia, and emesis...whazzup?

Journal: Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20020101

Title: Trends in antimalarial drugs prescribed in New Zealand 1993 to 1998.

Journal: Journal of travel medicine 20020101

Title: [Efficacy of mefloquine, halofantrine, and coarteme in the treatment of tropical malaria].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20020101

Title: Multifocal myoclonus associated with mefloquine chemoprophylaxis.

Journal: Clinical neuropharmacology 20020101

Title: Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand.

Journal: Malaria journal 20020101

Title: Malaria during a multinational military deployment: the comparative experience of the Italian, British and Australian Armed Forces in East Timor.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: Epidemiology of malaria from East Timor among Australian Defence Force personnel.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: A randomized, double-blind study on the efficacy and safety of a practical three-day regimen with artesunate and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in Africa.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: Plasmodium falciparum: effect of anti-malarial drugs on the production and secretion characteristics of histidine-rich protein II.

Journal: Experimental parasitology 20020101

Title: Episodic see-saw nystagmus in spino-cerebellar ataxia type 2 (SCA-2).

Journal: Cerebellum (London, England) 20020101

Title: Genomic analysis of mefloquine-resistant Plasmodium falciparum.

Journal: Nucleic acids research. Supplement (2001) 20020101

Title: Side effects of and compliance with malaria prophylaxis in children.

Journal: Journal of travel medicine 20020101

Title: Trends in malaria chemoprophylaxis prescription in South Africa 1994 to 2000.

Journal: Journal of travel medicine 20020101

Title: Paranoid psychosis related to mefloquine antimalarial prophylaxis.

Journal: Papua and New Guinea medical journal 20020101

Title: Treatment of falciparum malaria in Vietnamese children: the need for combination therapy and optimized dosage regimens.

Journal: Annals of tropical paediatrics 20011201

Title: Efficacy of mefloquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum infection in Machinga District, Malawi, 1998.

Journal: The American journal of tropical medicine and hygiene 20011201

Title: In vivo-in vitro model for the assessment of clinically relevant antimalarial cross-resistance.

Journal: The American journal of tropical medicine and hygiene 20011201

Title: Community-based program for malaria case management in the Brazilian Amazon.

Journal: The American journal of tropical medicine and hygiene 20011201

Title: Current drugs for antimalarial chemoprophylaxis: a review of efficacy and safety.

Journal: Journal of travel medicine 20011201

Title: In vitro susceptibility of Plasmodium falciparum isolates from Myanmar to antimalarial drugs.

Journal: The American journal of tropical medicine and hygiene 20011101

Title: Pulmonary toxicity with mefloquine.

Journal: The European respiratory journal 20011101

Title: Atovaquone-proguanil versus mefloquine for malaria prophylaxis in nonimmune travelers: results from a randomized, double-blind study.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011001

Title: Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK and HERG.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Pharmacokinetic-pharmacodynamic modelling of the antimalarial activity of mefloquine.

Journal: Parasitology 20011001

Title: Malaria remains a military medical problem.

Journal: Journal of the Royal Army Medical Corps 20011001

Title: [Danger of malaria self-treatment. Acute neurologic toxicity of mefloquine and its combination with pyrimethamine-sulfadoxine].

Journal: Presse medicale (Paris, France : 1983) 20010929

Title: Perspective on animal models: chronic intracellular infections.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010915

Title: Death from malaria following inappropriate chemoprophylaxis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010901

Title: Serious adverse events of mefloquine in relation to blood level and gender.

Journal: The American journal of tropical medicine and hygiene 20010901

Title: Development of stereoselective nonaqueous capillary electrophoresis system for the resolution of cationic and amphoteric analytes.

Journal: Electrophoresis 20010901

Title: The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase.

Journal: Pharmaceutical research 20010901

Title: Randomized trial of artesunate and mefloquine in comparison with quinine sulfate to treat P. falciparum malaria pregnant women.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010901

Title: Mefloquine-induced trigeminal sensory neuropathy.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010801

Title: Reversal of chloroquine and mefloquine resistance in Plasmodium falciparum by the two monoindole alkaloids, icajine and isoretuline.

Journal: Planta medica 20010801

Title: Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010715

Title: Sudden death in a traveller following halofantrine administration--Togo, 2000.

Journal: Canada communicable disease report = Releve des maladies transmissibles au Canada 20010715

Title: [Expanded arsenal for prevention and therapy. What is the value of the new malaria drugs? (interview by Waltraut Paukstadt)].

Journal: MMW Fortschritte der Medizin 20010705

Title: Pharmacokinetic interaction between mefloquine and ritonavir in healthy volunteers.

Journal: British journal of clinical pharmacology 20010601

Title: [Recommendations for prevention of malaria in patients with epilepsy].

Journal: Der Nervenarzt 20010601

Title: [Malaria--chemoprophylaxis 2001].

Journal: Therapeutische Umschau. Revue therapeutique 20010601

Title: Efficacy of dihydroartemisinin-mefloquine on acute uncomplicated falciparum malaria.

Journal: Chinese medical journal 20010601

Title: Antimalarial drugs exacerbate rat liver microsomal lipid peroxidation in the presence of oxidants.

Journal: Bioscience reports 20010601

Title: Bipolar disorder after mefloquine treatment.

Journal: Journal of psychiatry & neuroscience : JPN 20010501

Title: From the Centers for Disease Control and Prevention. Sudden death in a traveler following halofantrine administration--Togo, 2000.

Journal: JAMA 20010411

Title: Madagascan isolates of Plasmodium falciparum showing low sensitivity to artemether in vitro.

Journal: Annals of tropical medicine and parasitology 20010401

Title: Use of the DELI-microtest to determine the drug sensitivity of Plasmodium falciparum in Burkina Faso.

Journal: Annals of tropical medicine and parasitology 20010401

Title: Fake antimalaria drugs in Cambodia.

Journal: Lancet (London, England) 20010317

Title: Sudden death in a traveler following halofantrine administration--Togo, 2000.

Journal: MMWR. Morbidity and mortality weekly report 20010309

Title: Acute respiratory distress syndrome complicating Plasmodium vivax malaria.

Journal: Critical care medicine 20010301

Title: Drug resistant malaria on the Thai-Myanmar and Thai-Cambodian borders.

Journal: The Southeast Asian journal of tropical medicine and public health 20010301

Title: Coadministration of mefloquine and chloroqine: use of a pharmacokinetic-based approach to reduce toxicity.

Journal: The Pediatric infectious disease journal 20010201

Title: Malaria risk for travellers to Africa.

Journal: Releve epidemiologique hebdomadaire 20010126

Title: Declining chloroquine resistance of Plasmodium falciparum in Lambaréné, Gabon from 1992 to 1998.

Journal: Wiener klinische Wochenschrift 20010115

Title: Potentiation of halofantrine-induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine.

Journal: British journal of pharmacology 20010101

Title: Antimalarial chemoprophylaxis in infants and children.

Journal: Paediatric drugs 20010101

Title: Cognitive and neuropsychiatric side effects of mefloquine.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20010101

Title: Malaria antibodies and mefloquine levels among United Nations troops in Angola.

Journal: Journal of travel medicine 20010101

Title: Prolonged visual illusions induced by mefloquine (Lariam): a case report.

Journal: Journal of travel medicine 20010101

Title: Resistance of Plasmodium falciparum to antimalarial drugs in a highly endemic area of southern Viet Nam: a study in vivo and in vitro.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: Plasmodium falciparum: emerging mefloquine resistance in vitro in Para State, north Brazil.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: How can we do pharmacokinetic studies in the tropics?

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: The Italian army standpoint on malaria chemoprophylaxis.

Journal: Medecine tropicale : revue du Corps de sante colonial 20010101

Title: The malaria threat.

Journal: Medecine tropicale : revue du Corps de sante colonial 20010101

Title: Experiences with malaria chemoprophylaxis in Dutch troops.

Journal: Medecine tropicale : revue du Corps de sante colonial 20010101

Title: Assessment of susceptibility of Plasmodium falciparum to chloroquine, quinine, mefloquine, sulfadoxine-pyrimethamine and artemisinin in southern Viet Nam.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: A randomized controlled trial on the efficacy of alternative treatment regimens for uncomplicated falciparum malaria in a multidrug-resistant falciparum area of Bangladesh--narrowing the options for the National Malaria Control Programme?

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: Analysis of Pfmdr 1 gene in mefloquine-resistant Plasmodium falciparum.

Journal: Nucleic acids research. Supplement (2001) 20010101

Title: Preliminary assessment of the efficacy of mefloquine/-sulphadoxine/ pyrimethamine combination in the treatment of uncomplicated malaria in children in North Eastern Nigeria.

Journal: African journal of medicine and medical sciences 20010101

Title: Mefloquine-induced acute hepatitis.

Journal: Pharmacotherapy 20001201

Title: Antimicrobial activities of mefloquine and a series of related compounds.

Journal: Antimicrobial agents and chemotherapy 20000401

Title: Convulsions in non-epileptics due to mefloquine-fluoroquinolone co-administration.

Journal: The National medical journal of India 20000101

Title: [Neuropsychiatric symptoms in preventive antimalarial treatment with mefloquine: apropos of 2 cases].

Journal: L'Encephale 20000101

Title: Seizures after antimalarial medication in previously healthy persons.

Journal: Journal of travel medicine 20000101

Title: Another case of achalasia-microcephaly syndrome.

Journal: Clinical dysmorphology 19991001

Title: [Acute paranoid hallucinatory psychosis following mefloquine prophylaxis (Lariam)].

Journal: Psychiatrische Praxis 19990901

Title: Mefloquine is active in vitro and in vivo against Mycobacterium avium complex.

Journal: Antimicrobial agents and chemotherapy 19990801

Title: Dermatological adverse effects with the antimalarial drug mefloquine: a review of 74 published case reports.

Journal: Clinical and experimental dermatology 19990701

Title: [Neuropsychiatric side effects of malarial prophylaxis with mefloquine (Lariam)].

Journal: Harefuah 19990701

Title: [Long-lasting neuropsychiatric side-effects following mefloquine prophylaxis. A case after six weeks of initiating and lasting six months].

Journal: Ugeskrift for laeger 19990308

Title: 8-Aminoquinolines active against blood stage Plasmodium falciparum in vitro inhibit hematin polymerization.

Journal: Antimicrobial agents and chemotherapy 19990301

Title: [Convulsions during prophylactic use of mefloquine].

Journal: Nederlands tijdschrift voor geneeskunde 19990130

Title: Acute fatty liver after malaria prophylaxis with mefloquine.

Journal: Lancet (London, England) 19990123

Title: The effect of artesunate combined with standard antimalarials against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 19990101

Title: [Mefloquine and ototoxicity: a report of 3 cases].

Journal: La Clinica terapeutica 19990101

Title: Mefloquine-induced grand mal seizure in tubercular meningitis.

Journal: Panminerva medica 19981201

Title: [Convulsions during prophylactic use of mefloquine].

Journal: Nederlands tijdschrift voor geneeskunde 19981107

Title: A unique case of mefloquine-induced psoriasis.

Journal: Journal of travel medicine 19980901

Title: [Mefloquine: neuropsychiatric adverse effects are often severe and persistent long after withdrawal of the drug].

Journal: Ugeskrift for laeger 19980413

Title: Neuropsychiatric manifestations after mefloquine therapy for Plasmodium falciparum malaria: comparing a retrospective and a prospective study.

Journal: Tropical medicine & international health : TM & IH 19980201

Title: Case study: neuropsychiatric symptoms associated with the antimalarial agent mefloquine.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 19971101

Title: Spontaneous reports of psychiatric adverse effects to mefloquine in the Netherlands.

Journal: British journal of clinical pharmacology 19970701

Title: Tolerance of mefloquine by SwissAir trainee pilots.

Journal: The American journal of tropical medicine and hygiene 19970201

Title: Neuro-psychiatric effects of antimalarials.

Journal: European journal of clinical pharmacology 19970101

Title: Adverse effects and compliance with mefloquine or proguanil antimalarial chemoprophylaxis.

Journal: European journal of clinical pharmacology 19970101

Title: Immune hemolytic anemia associated with mefloquine.

Journal: Transfusion 19970101

Title: Adverse events associated with mefloquine. Study in returned travellers confirms authors' findings.

Journal: BMJ (Clinical research ed.) 19961214

Title: Atrial flutter with 1:1 conduction after administration of the antimalarial drug mefloquine.

Journal: Clinical cardiology 19961201

Title: Mefloquine induced grand mal seizure in a case of uncomplicated falciparum malaria.

Journal: The Journal of the Association of Physicians of India 19961001

Title: Comparison of adverse events associated with use of mefloquine and combination of chloroquine and proguanil as antimalarial prophylaxis: postal and telephone survey of travellers.

Journal: BMJ (Clinical research ed.) 19960831

Title: Tolerance of mefloquine chemoprophylaxis in Dutch military personnel.

Journal: The American journal of tropical medicine and hygiene 19960801

Title: Mefloquine-induced psychosis.

Journal: Annals of emergency medicine 19960601

Title: Cutaneous vasculitis associated with mefloquine.

Journal: Annals of internal medicine 19951201

Title: Adverse reaction to mefloquine associated with ethanol ingestion.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 19950215

Title: Mefloquine-induced grand mal seizure during malaria chemoprophylaxis in a non-epileptic subject.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 19950101

Title: Acute psychosis after mefloquine. Report of six cases.

Journal: Tropical and geographical medicine 19950101

Title: Mefloquine treatment of acute falciparum malaria: a prospective study of non-serious adverse effects in 3673 patients.

Journal: Bulletin of the World Health Organization 19950101

Title: Acute psychosis after mefloquine: a case report.

Journal: East African medical journal 19941201

Title: Severe psychiatric side effects observed during prophylaxis and treatment with mefloquine.

Journal: Archives of internal medicine 19941024

Title: Seizure associated with mefloquine for malaria prophylaxis.

Journal: The Medical journal of Australia 19941003

Title: Central anticholinergic syndrome with the antimalarial drug mefloquine.

Journal: The New England journal of medicine 19940707

Title: Quinine toxicity when given with doxycycline and mefloquine.

Journal: The Southeast Asian journal of tropical medicine and public health 19940601

Title: In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii.

Journal: Antimicrobial agents and chemotherapy 19940601

Title: Efficacy and tolerance of extended-dose halofantrine for drug-resistant falciparum malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 19940201

Title: Aplastic anemia during malarial prophylaxis with mefloquine.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 19940201

Title: [A case of mefloquine-resistant Plasmodium falciparum malaria with convulsion after antimalarial treatment].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 19940101

Title: [Cerebral spasm during malaria prophylaxis with mefloquine].

Journal: Deutsche medizinische Wochenschrift (1946) 19931223

Title: [Severe neuropsychiatric reaction following mefloquine use].

Journal: Medicina clinica 19931023

Title: Tolerability of prophylactic Lariam regimens.

Journal: Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) 19930901

Title: Mefloquine-associated cutaneous vasculitis.

Journal: International journal of dermatology 19930701

Title: Mefloquine.

Journal: Lancet (London, England) 19930619

Title: Anaesthesia emergence delirium after mefloquine prophylaxis.

Journal: Lancet (London, England) 19930306

Title: Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.

Journal: The American journal of tropical medicine and hygiene 19930301

Title: [Encephalopathy and memory disorders during treatments with mefloquine].

Journal: La Revue de medecine interne 19930101

Title: Abnormal circulatory control in falciparum malaria: the effects of antimalarial drugs.

Journal: European journal of clinical pharmacology 19930101

Title: Paresthesias and mefloquine prophylaxis.

Journal: Annals of internal medicine 19921215

Title: Acute depressive symptoms after mefloquine treatment.

Journal: The American journal of psychiatry 19920501

Title: [Psychotic episode caused by prevention of malaria with mefloquine. A case report].

Journal: Der Nervenarzt 19920501

Title: Effect of mefloquine on electrocardiographic changes in uncomplicated falciparum malaria patients.

Journal: The Southeast Asian journal of tropical medicine and public health 19920301

Title: [Suspected convulsive side-effect of mefloquine (Lariam)].

Journal: Der Nervenarzt 19911201

Title: Neuropsychiatric side effects after the use of mefloquine.

Journal: The American journal of tropical medicine and hygiene 19910701

Title: [Clinical experiences with mefloquine in tropical malaria--a prospective study].

Journal: Immunitat und Infektion 19910601

Title: Seizures after mefloquine.

Journal: Annals of internal medicine 19910601

Title: [Panic attack after therapeutic administration of mefloquine].

Journal: Annales de medecine interne 19910101

Title: Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis.

Journal: Antimicrobial agents and chemotherapy 19900701

Title: [Recurrent psychiatric manifestations during malaria prevention with mefloquine. A case report].

Journal: Therapie 19900101

Title: Neurologic reactions after a therapeutic dose of mefloquine.

Journal: The New England journal of medicine 19891116

Title: Acute psychosis after mefloquine.

Journal: Lancet (London, England) 19890729

Title: Tolerance of mefloquine alone and in combination with sulfadoxine-pyrimethamine in the prophylaxis of malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 19890101

Title: Kang J, et al. Interactions of the antimalarial drug mefloquine with the human cardiac potassium channels KvLQT1/minK andHERG. J Pharmacol Exp Ther. 2001 Oct;299(1):290-6.

Title: Yan KH, et al. Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling. Oncol Lett. 2013 May;5(5):1541-1545.

Title: Kaho Shionoya, et al. Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro. Front Microbiol. 2021 Apr 30;12:651403.

Title: Rafael Pacheco-Costa, et al. Reversal of loss of bone mass in old mice treated with mefloquine. Bone. 2018 Sep;114:22-31.

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Tags:51773-92-3 Molecular Formula|51773-92-3 MDL|51773-92-3 SMILES|51773-92-3 (R)-[2,8-bis(trifluoromethyl)quinolin-4-yl](2S)-piperidin-2-ylmethanol hydrochloride |Heterocyclic_Building_Blocks