Title: From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20180201

Title: From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20170801

Title: Polygoni Multiflori Radix derived anthraquinones alter bile acid disposition in sandwich-cultured rat hepatocytes.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20170401

Title: Emodin suppresses TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells through Notch signaling pathway.

Journal: Toxicology and applied pharmacology20170301

Title: Chemical Reactivity of Emodin and Its Oxidative Metabolites to Thiols.

Journal: Chemical research in toxicology20161219

Title: The natural anthraquinones from Rheum palmatum induced the metabolic disorder of melatonin by inhibiting human CYP and SULT enzymes.

Journal: Toxicology letters20161116

Title: Involvement of PI3K/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20160601

Title: Emodin isolated from Polygoni Multiflori Ramulus inhibits melanogenesis through the liver X receptor-mediated pathway.

Journal: Chemico-biological interactions20160425

Title: Emodin Attenuates Cigarette Smoke Induced Lung Injury in a Mouse Model via Suppression of Reactive Oxygen Species Production.

Journal: Journal of biochemical and molecular toxicology20151101

Title: Involvement of PPARγ in emodin-induced HK-2 cell apoptosis.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20150201

Title: Emodin inhibits human sperm functions by reducing sperm [Ca(2+)]i and tyrosine phosphorylation.

Journal: Reproductive toxicology (Elmsford, N.Y.)20150101

Title: In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats.

Journal: Chemico-biological interactions20140805

Title: Antitubercular and antibacterial activity of quinonoid natural products against multi-drug resistant clinical isolates.

Journal: Phytotherapy research : PTR20140701

Title: Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp.

Journal: Toxicology and applied pharmacology20140301

Title: Inhibition of Epstein-Barr virus lytic cycle by an ethyl acetate subfraction separated from Polygonum cuspidatum root and its major component, emodin.

Journal: Molecules (Basel, Switzerland)20140120

Title: Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions.

Journal: Journal of applied toxicology : JAT20140101

Title: Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.

Journal: British journal of pharmacology20131001

Title: Protective effects of emodin against cisplatin-induced oxidative stress in cultured human kidney (HEK 293) cells.

Journal: Journal of applied toxicology : JAT20130701

Title: Long-term treatment with san'o-shashin-to, a kampo medicine, markedly ameliorates cardiac ischemia-reperfusion injury in ovariectomized rats via the redox-dependent mechanism.

Journal: Circulation journal : official journal of the Japanese Circulation Society20130101

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry20121115

Title: Emodin inhibits invasion and migration of prostate and lung cancer cells by downregulating the expression of chemokine receptor CXCR4.

Journal: Immunopharmacology and immunotoxicology20121001

Title: Use of cetyltrimethylammonium bromide as a simple probe for rapid determination of emodin by resonance light scattering technique.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20121001

Title: Irbesartan and emodin on myocardial remodeling in Goldblatt hypertensive rats.

Journal: Journal of cardiovascular pharmacology20121001

Title: Bioactive anthraquinones from endophytic fungus Aspergillus versicolor isolated from red sea algae.

Journal: Archives of pharmacal research20121001

Title: A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats.

Journal: Toxicology and applied pharmacology20120915

Title: Emodin induces embryonic toxicity in mouse blastocysts through apoptosis.

Journal: Toxicology20120904

Title: Determination of emodin by hexadecyl trimethyl ammonium bromide sensitized fluorescence quenching method of the derivatives of calix[4]arene.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20120901

Title: Emodin, an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, regulates adipocyte function in vitro and exerts anti-diabetic effect in ob/ob mice.

Journal: Acta pharmacologica Sinica20120901

Title: A strategy for detecting absorbed bioactive compounds for quality control in the water extract of rhubarb by ultra performance liquid chromatography with photodiode array detector.

Journal: Chinese journal of integrative medicine20120901

Title: Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats.

Journal: Chinese journal of integrative medicine20120901

Title: A new polymorph of physcion.

Journal: Acta crystallographica. Section C, Crystal structure communications20120801

Title: Effects of an anthraquinone derivative from Rheum officinale Baill, emodin, on airway responses in a murine model of asthma.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120701

Title: Discovery and structure-activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2.

Journal: Bioorganic & medicinal chemistry letters20120701

Title: Emodin, a naturally occurring anthraquinone, ameliorates experimental autoimmune myocarditis in rats.

Journal: The Tohoku journal of experimental medicine20120701

Title: Study of DNA-emodin interaction by FTIR and UV-vis spectroscopy.

Journal: Journal of photochemistry and photobiology. B, Biology20120604

Title: Emodin potentiates the antitumor effects of gemcitabine in PANC-1 pancreatic cancer xenograft model in vivo via inhibition of inhibitors of apoptosis.

Journal: International journal of oncology20120601

Title: Emodin inhibits tumor necrosis factor-α-induced migration and inflammatory responses in rat aortic smooth muscle cells.

Journal: International journal of molecular medicine20120601

Title: A novel UPLC-MS/MS method for simultaneous quantification of rhein, emodin, berberine and baicalin in rat plasma and its application in a pharmacokinetic study.

Journal: Bioanalysis20120601

Title: Library-based discovery of DYRK1A/CLK1 inhibitors from natural product extracts.

Journal: Planta medica20120601

Title: Emodin protects against high-fat diet-induced obesity via regulation of AMP-activated protein kinase pathways in white adipose tissue.

Journal: Planta medica20120601

Title: Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.

Journal: Biochemical and biophysical research communications20120525

Title: Emodin promoted pancreatic claudin-5 and occludin expression in experimental acute pancreatitis rats.

Journal: World journal of gastroenterology20120507

Title: Effects of emodin and vitamin C on growth performance, biochemical parameters and two HSP70s mRNA expression of Wuchang bream (Megalobrama amblycephala Yih) under high temperature stress.

Journal: Fish & shellfish immunology20120501

Title: Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120501

Title: On the novel action of melanolysis by a leaf extract of Aloe vera and its active ingredient aloin, potent skin depigmenting agents.

Journal: Planta medica20120501

Title: [Emodin combined gemcitabine inhibited the growth of pancreatic cancer in vitro and in vivo and its mechanisms study].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20120501

Title: [Chemical constituents of Dolomiaea souliei].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20120501

Title: [Rapid cloning and functional characterization of hypericin synthase gene].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20120501

Title: Emodin reverses gemcitabine resistance in pancreatic cancer cells via the mitochondrial apoptosis pathway in vitro.

Journal: International journal of oncology20120401

Title: Toxicity of raw and processed roots of Polygonum multiflorum.

Journal: Fitoterapia20120401

Title: Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors.

Journal: Bioorganic & medicinal chemistry20120401

Title: Characteristics of emodin on modulating the contractility of jejunal smooth muscle.

Journal: Canadian journal of physiology and pharmacology20120401

Title: Hepatoprotection of emodin and Polygonum multiflorum against CCl(4)-induced liver injury.

Journal: Pharmaceutical biology20120301

Title: A facile synthesis of emodin derivatives, emodin carbaldehyde, citreorosein, and their 10-deoxygenated derivatives and their inhibitory activities on μ-calpain.

Journal: Archives of pharmacal research20120301

Title: Inhibition of cytochrome p450 enzymes by quinones and anthraquinones.

Journal: Chemical research in toxicology20120220

Title: Apoptosis by aloe-emodin is mediated through down-regulation of calpain-2 and ubiquitin-protein ligase E3A in human hepatoma Huh-7 cells.

Journal: Cell biology international20120201

Title: Structural and functional analysis of the flexible regions of the catalytic α-subunit of protein kinase CK2.

Journal: Journal of structural biology20120201

Title: [Chemical constituents of Berchemia lineate].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20120201

Title: Microwave-assisted extraction performed in low temperature and in vacuo for the extraction of labile compounds in food samples.

Journal: Analytica chimica acta20120127

Title: Simultaneous determination of eight anthraquinones in Semen Cassiae by HPLC-DAD.

Journal: Phytochemical analysis : PCA20120101

Title: Emodin induces chloride secretion in rat distal colon through activation of mast cells and enteric neurons.

Journal: British journal of pharmacology20120101

Title: Rhein induces apoptosis in human breast cancer cells.

Journal: Evidence-based complementary and alternative medicine : eCAM20120101

Title: Chemical-based species classification of rhubarb using simultaneous determination of five bioactive substances by HPLC and LDA analysis.

Journal: Phytochemical analysis : PCA20120101

Title: Synthesis and antitumor activity of conjugates of 5-Fluorouracil and emodin.

Journal: European journal of medicinal chemistry20120101

Title: Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity.

Journal: Bioorganic & medicinal chemistry letters20120101

Title: Comparison of dispersive liquid-liquid microextraction based on organic solvent and ionic liquid combined with high-performance liquid chromatography for the analysis of emodin and its metabolites in urine samples.

Journal: Journal of separation science20120101

Title: Identification of small molecule activators of the janus kinase/signal transducer and activator of transcription pathway using a cell-based screen.

Journal: Biological & pharmaceutical bulletin20120101

Title: Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats.

Journal: International journal of molecular sciences20120101

Title: Enhancement of fluoride activity against Streptococcus mutans biofilms by a substance separated from Polygonum cuspidatum.

Journal: Biofouling20120101

Title: Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways.

Journal: Evidence-based complementary and alternative medicine : eCAM20120101

Title: Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM20120101

Title: Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin.

Journal: International journal of nanomedicine20120101

Title: [Determination of four anthraquinones in Sanhuang tablets by QAMS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20120101

Title: Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis.

Journal: PloS one20120101

Title: Emodin affects ERCC1 expression in breast cancer cells.

Journal: Journal of translational medicine20120101

Title: Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of β-hematin formation.

Journal: Journal of pharmaceutical and biomedical analysis20111215

Title: Emodin-induced microglial apoptosis is associated with TRB3 induction.

Journal: Immunopharmacology and immunotoxicology20111201

Title: Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation.

Journal: International journal of oncology20111201

Title: Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm.

Journal: Journal of medical microbiology20111201

Title: Emodin, a naturally occurring anthraquinone derivative, suppresses IgE-mediated anaphylactic reaction and mast cell activation.

Journal: Biochemical pharmacology20111201

Title: Surface-initiated molecularly imprinted polymeric column: In situ synthesis and application for semi-preparative separation by high performance liquid chromatography.

Journal: Journal of chromatography. A20111111

Title: Toxicological effect of emodin in mouse testicular gene expression profile.

Journal: Journal of applied toxicology : JAT20111101

Title: Comparative analyses of chromatographic fingerprints of the roots of Polygonum multiflorum Thunb. and their processed products using RRLC/DAD/ESI-MS(n).

Journal: Planta medica20111101

Title: Enhanced antitumor efficacy by the combination of emodin and gemcitabine against human pancreatic cancer cells via downregulation of the expression of XIAP in vitro and in vivo.

Journal: International journal of oncology20111101

Title: Emodin potentiates the anticancer effect of cisplatin on gallbladder cancer cells through the generation of reactive oxygen species and the inhibition of survivin expression.

Journal: Oncology reports20111101

Title: Development of a liquid chromatography tandem mass spectrometry method for simultaneous determination of eight adulterants in slimming functional foods.

Journal: Journal of chromatography. A20111021

Title: Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata.

Journal: Journal of ethnopharmacology20111011

Title: A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract.

Journal: Journal of ethnopharmacology20111011

Title: Blockade of Her2/neu binding to Hsp90 by emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2/neu.

Journal: Molecular pharmaceutics20111003

Title: Repair and reconstruction of a resected tumor defect using a composite of tissue flap-nanotherapeutic-silk fibroin and chitosan scaffold.

Journal: Annals of biomedical engineering20110901

Title: In vitro accelerated mass propagation and ex vitro evaluation of Aloe vera L. with aloin content and superoxide dismutase activity.

Journal: Natural product research20110801

Title: Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines.

Journal: Bioorganic & medicinal chemistry letters20110715

Title: Development and validation of a highly rapid and sensitive LC-MS/MS method for determination of SZ-685C, an investigational marine anticancer agent, in rat plasma--application to a pharmacokinetic study in rats.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20110715

Title: The use of response surface methodology to optimize the ultrasound-assisted extraction of five anthraquinones from Rheum palmatum L.

Journal: Molecules (Basel, Switzerland)20110715

Title: [Chemical constituents of Carya cathayensis and their antitumor bioactivity].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20110701

Title: Hepatitis C virus and alcohol: same mitotic targets but different signaling pathways.

Journal: Journal of hepatology20110501

Title: Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis.

Journal: Oncology reports20110501

Title: Emodin and [6]-gingerol lessen hypoxia-induced embryotoxicities in cultured mouse whole embryos via upregulation of hypoxia-inducible factor 1α and intracellular superoxide dismutases.

Journal: Reproductive toxicology (Elmsford, N.Y.)20110501

Title: Inhibition of experimental atopic dermatitis by rhubarb (rhizomes of Rheum tanguticum) and 5-lipoxygenase inhibition of its major constituent, emodin.

Journal: Phytotherapy research : PTR20110501

Title: [Alkaloids and anthraquinones from branches and leaves of uvaria kurzii].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20110501

Title: Sensitive and robust UPLC-MS/MS method to determine the gender-dependent pharmacokinetics in rats of emodin and its glucuronide.

Journal: Journal of pharmaceutical and biomedical analysis20110405

Title: Effect of emodin on neuropathic pain transmission mediated by P2X2/3 receptor of primary sensory neurons.

Journal: Brain research bulletin20110405

Title: Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells.

Journal: Journal of cellular biochemistry20110401

Title: [Effect of emodin combined gemcitabine on the growth and apoptosis of pancreatic cancer cell line BxPC-3 in vitro].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20110401

Title: Apoptotic effect of Polygonum Cuspidatum in oral cancer cells through the regulation of specificity protein 1.

Journal: Oral diseases20110301

Title: Modulation of Rad51, ERCC1, and thymidine phosphorylase by emodin result in synergistic cytotoxic effect in combination with capecitabine.

Journal: Biochemical pharmacology20110301

Title: [Tissue distribution of free anthraquinones in SD rats after orally administered extracts from raw and prepared rhubarbs].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20110301

Title: [Studies on identification and secondary metabolites of endophytic fungi strain E8 from Curcuma wenyujin].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20110301

Title: Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20110201

Title: Solid-phase extraction and ultra high-performance liquid chromatography tandem mass spectrometry analysis of the gastrointestinal absorption of emodin in different digestive segments of rats.

Journal: Journal of separation science20110201

Title: [Role of nuclear factor-kappaB on emodin-induced sensitization of pancreatic cancer to gemcitabine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20110201

Title: The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo.

Journal: Journal of ethnopharmacology20110127

Title: Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.

Journal: Journal of medicinal chemistry20110127

Title: Preparative isolation of three anthraquinones from Rumex japonicus by high-speed counter-current chromatography.

Journal: Molecules (Basel, Switzerland)20110127

Title: Selective determination of aloin in different matrices by HPTLC densitometry in fluorescence mode.

Journal: Journal of pharmaceutical and biomedical analysis20110125

Title: Effects of food and gender on the pharmacokinetics of rhein and emodin in rats after oral dosing with Da-Cheng-Qi decoction.

Journal: Phytotherapy research : PTR20110101

Title: New anthraquinone dimer from the root bark of Cassia artemisioides (Gaudich. Ex. DC) Randell.

Journal: Journal of Asian natural products research20110101

Title: Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants.

Journal: PloS one20110101

Title: Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB.

Journal: Molecular medicine reports20110101

Title: Emodin inhibits extracellular matrix synthesis by suppressing p38 and ERK1/2 pathways in TGF-β1-stimulated NRK-49F cells.

Journal: Molecular medicine reports20110101

Title: Endocrocin and its derivatives from the Japanese mealybug Planococcus kraunhiae.

Journal: Bioscience, biotechnology, and biochemistry20110101

Title: Effect of clone selection, nitrogen supply, leaf damage and mycorrhizal fungi on stilbene and emodin production in knotweed.

Journal: BMC plant biology20110101

Title: Emodin Induces Apoptotic Death in Murine Myelomonocytic Leukemia WEHI-3 Cells In Vitro and Enhances Phagocytosis in Leukemia Mice In Vivo.

Journal: Evidence-based complementary and alternative medicine : eCAM20110101

Title: Emodin inhibits proinflammatory responses and inactivates histone deacetylase 1 in hypoxic rheumatoid synoviocytes.

Journal: Biological & pharmaceutical bulletin20110101

Title: Combined phytochemistry and chemotaxis assays for identification and mechanistic analysis of anti-inflammatory phytochemicals in Fallopia japonica.

Journal: PloS one20110101

Title: Anthraquinones of Cissus populnea Guill & Perr (Amplidaceae).

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM20110101

Title: Approach toward the total synthesis of 5-hydroxyaloin A.

Journal: Organic letters20101217

Title: Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells.

Journal: British journal of pharmacology20101201

Title: Emodin triggers DNA double-strand breaks by stabilizing topoisomerase II-DNA cleavage complexes and by inhibiting ATP hydrolysis of topoisomerase II.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20101201

Title: The anthraquinone derivative emodin attenuates methamphetamine-induced hyperlocomotion and startle response in rats.

Journal: Pharmacology, biochemistry, and behavior20101201

Title: [Determination of rat serum emodin level by microemulsion liquid chromatography with direct sample loading].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20101201

Title: [Emodin enhances antitumor effect of gemcitabine in model of SW1990 cell xenograft on athymic mouse].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20101201

Title: Dose-dependent hepatoprotective effect of emodin against acetaminophen-induced acute damage in rats.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie20101101

Title: Synergistic effect of emodin in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus.

Journal: Pharmaceutical biology20101101

Title: [Protective effects of emodin on intestinal lesion in rat model with acute necrotizing pancreatitis].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20101101

Title: Influence of carbon source on growth and mycotoxin production by isolates of Pyrenophora tritici-repentis from wheat.

Journal: Canadian journal of microbiology20101001

Title: In vitro & in vivo assessment of a herbal formula used topically for bone fracture treatment.

Journal: Journal of ethnopharmacology20100915

Title: Emodin, a natural product, selectively inhibits 11beta-hydroxysteroid dehydrogenase type 1 and ameliorates metabolic disorder in diet-induced obese mice.

Journal: British journal of pharmacology20100901

Title: Inhibition of ATP-induced macrophage death by emodin via antagonizing P2X7 receptor.

Journal: European journal of pharmacology20100825

Title: Neuroprotective effects of emodin in rat cortical neurons against beta-amyloid-induced neurotoxicity.

Journal: Brain research20100806

Title: Emodin enhances cisplatin-induced cytotoxicity via down-regulation of ERCC1 and inactivation of ERK1/2.

Journal: Lung cancer (Amsterdam, Netherlands)20100801

Title: Apoptosis induced by emodin is associated with alterations of intracellular acidification and reactive oxygen species in EC-109 cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire20100801

Title: Synthesis and biological evaluation of cytotoxic activity of novel anthracene L-rhamnopyranosides.

Journal: Bioorganic & medicinal chemistry20100715

Title: Physcion, a natural anthraquinone derivative, enhances the gene expression of leaf-specific thionin of barley against Blumeria graminis.

Journal: Pest management science20100701

Title: [Studies on the chemical constituents of radix Boehmeriae].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100701

Title: [Neuroprotective effects of emodin on primary rat cortical neurons apoptosis induced by hydrogen peroxide].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100701

Title: Emodin enhances alveolar epithelial barrier function in rats with experimental acute pancreatitis.

Journal: World journal of gastroenterology20100628

Title: Qualitative and quantitative analysis of anthraquinone derivatives in rhizomes of tissue culture-raised Rheum emodi Wall. plants.

Journal: Journal of plant physiology20100615

Title: 4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin.

Journal: Journal of cellular and molecular medicine20100601

Title: Protective effects of emodin combined with danshensu on experimental severe acute pancreatitis.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20100601

Title: Alaternin attenuates delayed neuronal cell death induced by transient cerebral hypoperfusion in mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20100601

Title: 5alpha-reductase inhibitory components as antiandrogens from herbal medicine.

Journal: Journal of acupuncture and meridian studies20100601

Title: Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9.

Journal: International journal of oncology20100501

Title: Synthesis of cytotoxic and antioxidant Schiff's base analogs of aloin.

Journal: Journal of Asian natural products research20100501

Title: A new bianthracene C-arabinopyranoside from Senna septemtrionalis.

Journal: Natural product communications20100501

Title: Pharmacokinetic comparison in rats of six bioactive compounds between Da-Cheng-Qi decoction and its parent herbal medicines.

Journal: Natural product communications20100501

Title: Emodin enhances sensitivity of gallbladder cancer cells to platinum drugs via glutathion depletion and MRP1 downregulation.

Journal: Biochemical pharmacology20100415

Title: Physcion-8-O-beta-D-glucopyranoside enhances the commitment of mouse mesenchymal progenitors into osteoblasts and their differentiation: Possible involvement of signaling pathways to activate BMP gene expression.

Journal: Journal of cellular biochemistry20100415

Title: A rapid HPLC/ESI-MS/MS method for quantitative analysis of isovalerylshikonin in rat plasma.

Journal: Biomedical chromatography : BMC20100401

Title: Anti-diabetic effects of emodin involved in the activation of PPARgamma on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice.

Journal: Fitoterapia20100401

Title: Structural basis for decreased affinity of Emodin binding to Val66-mutated human CK2 alpha as determined by molecular dynamics.

Journal: Journal of molecular modeling20100401

Title: A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease.

Journal: Journal of enzyme inhibition and medicinal chemistry20100401

Title: Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats.

Journal: Journal of pharmaceutical sciences20100401

Title: Role of Rad51 down-regulation and extracellular signal-regulated kinases 1 and 2 inactivation in emodin and mitomycin C-induced synergistic cytotoxicity in human non-small-cell lung cancer cells.

Journal: Molecular pharmacology20100401

Title: [Effect of emodin on P-gp expression in intrahepatic cholestatic rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20100401

Title: [Studies on the chemical constituents of Kalimeris indica].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100401

Title: [Liposomal encapsulation of free anthraquinones in rhizoma et radix rhei and its quality control].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100401

Title: Mixed hemimicelles SPE based on CTAB-coated Fe3O4/SiO2 NPs for the determination of herbal bioactive constituents from biological samples.

Journal: Talanta20100315

Title: Biotransformation of paeonol and emodin by transgenic crown galls of Panax quinquefolium.

Journal: Applied biochemistry and biotechnology20100301

Title: Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum.

Journal: Oral diseases20100301

Title: Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.

Journal: Anticancer research20100301

Title: Suppression of ERCC1 and Rad51 expression through ERK1/2 inactivation is essential in emodin-mediated cytotoxicity in human non-small cell lung cancer cells.

Journal: Biochemical pharmacology20100215

Title: Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase.

Journal: Bioorganic & medicinal chemistry20100215

Title: Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo.

Journal: European journal of pharmacology20100210

Title: Protein kinase inhibitors emodin and dichloro-ribofuranosylbenzimidazole modulate the cellular accumulation and cytotoxicity of cisplatin in a schedule-dependent manner.

Journal: Cancer chemotherapy and pharmacology20100201

Title: Screening of Kit inhibitors: suppression of Kit signaling and melanogenesis by emodin.

Journal: Phytotherapy research : PTR20100201

Title: Crystal structure of Hyp-1, a St. John's wort protein implicated in the biosynthesis of hypericin.

Journal: Journal of structural biology20100201

Title: Docking and 3D-QSAR studies of 7-hydroxycoumarin derivatives as CK2 inhibitors.

Journal: European journal of medicinal chemistry20100101

Title: Comparison of three different extraction methods and HPLC determination of the anthraquinones aloe-emodine, emodine, rheine, chrysophanol and physcione in the bark of Rhamnus alpinus L. (Rhamnaceae).

Journal: Phytochemical analysis : PCA20100101

Title: Factors influencing the production of stilbenes by the knotweed, Reynoutria x bohemica.

Journal: BMC plant biology20100101

Title: A CE-based assay for human protein kinase CK2 activity measurement and inhibitor screening.

Journal: Electrophoresis20100101

Title: Emodin and rhein inhibit LIGHT-induced monocytes migration by blocking of ROS production.

Journal: Vascular pharmacology20100101

Title: The correlation between bioactive components of Fallopia multiflora root and environmental factors.

Journal: The American journal of Chinese medicine20100101

Title: Emodin down-regulates expression of TRPV1 mRNA and its function in DRG neurons in vitro.

Journal: The American journal of Chinese medicine20100101

Title: Differential functional genomic effects of anti-inflammatory phytocompounds on immune signaling.

Journal: BMC genomics20100101

Title: Inhibitory effect of emodin and Astragalus polysaccharide on the replication of HBV.

Journal: World journal of gastroenterology20091207

Title: [Effects of emodin on cell apoptosis of intestinal mucosa and serum leptin in rats with severe acute pancreatitis].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine20091201

Title: [Studies on the chemical constituents of Rumex crispus].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20091201

Title: Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells.

Journal: European journal of pharmacology20091125

Title: Characterization of emodin metabolites in Raji cells by LC-APCI-MS/MS.

Journal: Bioorganic & medicinal chemistry20091101

Title: Emodin protects rat liver from CCl(4)-induced fibrogenesis via inhibition of hepatic stellate cells activation.

Journal: World journal of gastroenterology20091014

Title: Validation of a new yeast-based reporter assay consisting of human estrogen receptors alpha/beta and coactivator SRC-1: application for detection of estrogenic activity in environmental samples.

Journal: Environmental toxicology20091001

Title: In vitro anti-fibrotic activities of herbal compounds and herbs.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Light-independent metabolomics of endophytic Thielavia subthermophila provides insight into microbial hypericin biosynthesis.

Journal: Journal of natural products20091001

Title: Aggregation of antitumoral drug emodin on Ag nanoparticles: SEF, SERS and fluorescence lifetime experiments.

Journal: Physical chemistry chemical physics : PCCP20091001

Title: Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma.

Journal: Experimental & molecular medicine20090930

Title: Emodin enhances gefitinib-induced cytotoxicity via Rad51 downregulation and ERK1/2 inactivation.

Journal: Experimental cell research20090910

Title: Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew.

Journal: Plant physiology and biochemistry : PPB20090901

Title: Emodin inhibits voltage-dependent potassium current in guinea pig gallbladder smooth muscle.

Journal: Basic & clinical pharmacology & toxicology20090901

Title: Inhibition of HIV-1 ribonuclease H activity by novel frangula-emodine derivatives.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20090901

Title: Emodin has cytotoxic and protective effects in rat C6 glioma cells: roles of Mdr1a and nuclear factor kappaB in cell survival.

Journal: The Journal of pharmacology and experimental therapeutics20090901

Title: Simultaneous determination of seven components in Qibaomeiran pill by HPLC-DAD.

Journal: Journal of chromatographic science20090901

Title: Ultraviolet light absorption of an ophthalmic formulation with Aloe extracts.

Journal: Natural product communications20090901

Title: Study on the anthraquinones separated from the cultivation of Trichoderma harzianum strain Th-R16 and their biological activity.

Journal: Journal of agricultural and food chemistry20090826

Title: Emodin suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose.

Journal: Molecular and cellular endocrinology20090813

Title: Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology.

Journal: International immunopharmacology20090801

Title: Emodin augments calcium activated chloride channel in colonic smooth muscle cells by Gi/Go protein.

Journal: European journal of pharmacology20090801

Title: In vivo pharmacokinetics comparisons of icariin, emodin and psoralen from gan-kang granules and extracts of herba Epimedii, Nepal dock root, Ficus hirta yahl.

Journal: Journal of ethnopharmacology20090730

Title: Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2.

Journal: The Biochemical journal20090715

Title: The comparative toxicity to soil invertebrates of natural chemicals and their synthetic analogues.

Journal: Chemosphere20090701

Title: Chromatin-level regulation of biosynthetic gene clusters.

Journal: Nature chemical biology20090701

Title: Natural anthraquinone derivatives from a marine mangrove plant-derived endophytic fungus Eurotium rubrum: structural elucidation and DPPH radical scavenging activity.

Journal: Journal of microbiology and biotechnology20090701

Title: Positive correlations between hypericin and putative precursors detected in the quantitative secondary metabolite spectrum of Hypericum.

Journal: Phytochemistry20090701

Title: [Study on the chemical constituents of Uvaria microcarpa].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20090701

Title: High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

Journal: Journal of medicinal chemistry20090625

Title: Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid.

Journal: Bioorganic & medicinal chemistry letters20090601

Title: Potentiation of the effect of gemcitabine by emodin in pancreatic cancer is associated with survivin inhibition.

Journal: Biochemical pharmacology20090601

Title: [Studies on the chemical constituents of the leaves of Polygonum multiflorum].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20090601

Title: [Simultaneous determination of anthraquinones in Liuwei'anxiao capsules by HPLC].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20090601

Title: Bioassay-guided separation of citreorosein and other oestrogenic compounds from Polygonum cuspidatum.

Journal: Phytotherapy research : PTR20090501

Title: [Effect and mechanism of emodin on cholestatic hepatitis].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20090501

Title: Evaluation of aloin and aloe-emodin as anti-inflammatory agents in aloe by using murine macrophages.

Journal: Bioscience, biotechnology, and biochemistry20090423

Title: Resorufin: a lead for a new protein kinase CK2 inhibitor.

Journal: Anti-cancer drugs20090401

Title: Emodin and baicalein inhibit pancreatic stromal derived factor-1 expression in rats with acute pancreatitis.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT20090401

Title: [Chemical study on petroleum ether portion of Sarcandra hainanensis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20090401

Title: [Therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof: experiment with rats].

Journal: Zhonghua yi xue za zhi20090317

Title: One single standard substance for the determination of multiple anthraquinone derivatives in rhubarb using high-performance liquid chromatography-diode array detection.

Journal: Journal of chromatography. A20090313

Title: Emodin reverses CCl induced hepatic cytochrome P450 (CYP) enzymatic and ultrastructural changes: The in vivo evidence.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology20090301

Title: Quantitative HPLC determination and extraction of anthraquinones in Senna alata leaves.

Journal: Journal of chromatographic science20090301

Title: [Study on the optimal extracion craft of Xiaochuang gel by central composite design-response surface methodology].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20090301

Title: Up-regulation of Toll-like receptor 4 was suppressed by emodin and baicalin in the setting of acute pancreatitis.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie20090201

Title: Inhibitory effect of emodin on bleomycin-induced pulmonary fibrosis in mice.

Journal: Clinical and experimental pharmacology & physiology20090201

Title: Hypoglycaemic and hypolipidaemic effects of emodin and its effect on L-type calcium channels in dyslipidaemic-diabetic rats.

Journal: Clinical and experimental pharmacology & physiology20090101

Title: Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways.

Journal: Anticancer research20090101

Title: Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization.

Journal: BMC microbiology20090101

Title: Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53.

Journal: Cancer cell international20090101

Title: Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection.

Journal: Phytochemical analysis : PCA20090101

Title: Chinese medicines as a resource for liver fibrosis treatment.

Journal: Chinese medicine20090101

Title: Is senna laxative use associated to cathartic colon, genotoxicity, or carcinogenicity?

Journal: Journal of toxicology20090101

Title: The toxicity of aconitine, emodin on ICC cell and the antagonist effect of the compatibility.

Journal: European journal of drug metabolism and pharmacokinetics20090101

Title: Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay.

Journal: Phytochemistry20081201

Title: Microwave-assisted aqueous two-phase extraction of piceid, resveratrol and emodin from Polygonum cuspidatum by ethanol/ammonium sulphate systems.

Journal: Biotechnology letters20081201

Title: Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20081201

Title: A new chalcone glycoside from Rhamnus nipalensis.

Journal: Natural product research20081201

Title: Structural elucidation of in vitro metabolites of emodin by liquid chromatography-tandem mass spectrometry.

Journal: Biomedical chromatography : BMC20081101

Title: Emodin increases Ca(2+) influx through L-type Ca(2+) channel in guinea pig gallbladder smooth muscle.

Journal: European journal of pharmacology20081024

Title: Participation of cathepsin B in emodin-induced apoptosis in HK-2 Cells.

Journal: Toxicology letters20081001

Title: Emodin is a novel alkaline nuclease inhibitor that suppresses herpes simplex virus type 1 yields in cell cultures.

Journal: British journal of pharmacology20080901

Title: Selective on-line extraction of trans-resveratrol and emodin from Polygonum cuspidatum using molecularly imprinted polymer.

Journal: Journal of chromatographic science20080901

Title: [Studies on the chemical constituents of Rabdosia rubescens].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20080901

Title: Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway.

Journal: European journal of pharmacology20080820

Title: [Studies on chemical constituents from rattan of Polygonum multiflorum].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20080801

Title: Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction.

Journal: Journal of pharmaceutical and biomedical analysis20080715

Title: Correlation between reduction potentials and inhibitions of Epstein-Barr virus activation by anthraquinone derivatives.

Journal: Bioorganic & medicinal chemistry letters20080715

Title: Study of vacuum microwave-assisted extraction of polyphenolic compounds and pigment from Chinese herbs.

Journal: Journal of chromatography. A20080711

Title: [Study on the chemical constituents of Rhizoma Cyperi].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20080701

Title: Protective effects of emodin and astragalus polysaccharides on chronic hepatic injury in rats.

Journal: Chinese medical journal20080605

Title: Tolerance of the lichen Xanthoria parietina (L.) Th. Fr. to metal stress.

Journal: Ecotoxicology and environmental safety20080601

Title: Study of interactions of anthraquinones with DNA using ethidium bromide as a fluorescence probe.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20080601

Title: Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones.

Journal: European journal of medicinal chemistry20080601

Title: Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum.

Journal: Archives of pharmacal research20080601

Title: Emodin-induced apoptosis in human breast cancer BCap-37 cells through the mitochondrial signaling pathway.

Journal: Archives of pharmacal research20080601

Title: Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavage.

Journal: Molecular cancer therapeutics20080601

Title: Inhibition of casein kinase 2 enhances the death ligand- and natural kiler cell-induced hepatocellular carcinoma cell death.

Journal: Clinical and experimental immunology20080501

Title: Emodin accelerates osteoblast differentiation through phosphatidylinositol 3-kinase activation and bone morphogenetic protein-2 gene expression.

Journal: International immunopharmacology20080501

Title: Novel anti-angiogenic compounds for application in tumor therapy - COP9 signalosome-associated kinases as possible targets.

Journal: Mini reviews in medicinal chemistry20080501

Title: Emodin promotes atherosclerotic plaque stability in fat-fed apolipoprotein E-deficient mice.

Journal: The Tohoku journal of experimental medicine20080501

Title: [Studies on chemical constituents and volatile oil of Xiaochengqi decoction].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20080501

Title: Pest-managing activities of plant extracts and anthraquinones from Cassia nigricans from Burkina Faso.

Journal: Bioresource technology20080401

Title: A new spiroketal from Aspergillus terreus, an endophytic fungus in Opuntia ficusindica Mill.

Journal: Journal of basic microbiology20080401

Title: The effect of emodin on VEGF receptors in human colon cancer cells.

Journal: Cancer biotherapy & radiopharmaceuticals20080401

Title: [Emodin induces apoptosis of cancer cells and inhibits retinoid X receptor transcriptional activity].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20080401

Title: The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin.

Journal: Journal of molecular biology20080314

Title: Aloin induces apoptosis in Jurkat cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20080301

Title: Simultaneous determination by UPLC-ESI-MS of scoparone, capillarisin, rhein, and emodin in rat urine after oral administration of Yin Chen Hao Tang preparation.

Journal: Journal of separation science20080301

Title: [Theoretical and experimental studies on solubility parameters of multiple components for traditional Chinese materia medica with HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20080301

Title: Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase.

Journal: Biochemistry20080219

Title: Antiplasmodial compounds from Cassia siamea stem bark extract.

Journal: Phytotherapy research : PTR20080201

Title: Inhibitory effects of emodin on the proliferation of cultured rat vascular smooth muscle cell-induced by angiotensin II.

Journal: Phytotherapy research : PTR20080201

Title: An endophytic fungus from Hypericum perforatum that produces hypericin.

Journal: Journal of natural products20080201

Title: [A new qualitative and quantitative analytical method of chromatographic fingerprints: total quantum statistical moment].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20080201

Title: [The studies on the Ku Huang granula technology].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20080201

Title: Studies of interaction of emodin and DNA in the presence of ethidium bromide by spectroscopic method.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20080101

Title: Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati.

Journal: The Journal of pharmacy and pharmacology20080101

Title: Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis.

Journal: Neoplasia (New York, N.Y.)20080101

Title: Topical anti-inflammatory activity of Polygonum cuspidatum extract in the TPA model of mouse ear inflammation.

Journal: Journal of inflammation (London, England)20080101

Title: The anthraquinone derivative Emodin ameliorates neurobehavioral deficits of a rodent model for schizophrenia.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20080101

Title: Emodin upregulates urokinase plasminogen activator, plasminogen activator inhibitor-1 and promotes wound healing in human fibroblasts.

Journal: Vascular pharmacology20080101

Title: [Inhibitory effects of emodin on proliferation of rat vascular smooth muscle cell induced by angiotensin II].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20080101

Title: Feasibility evaluation of emodin (rhubarb extract) as an inhibitor of pancreatic cancer cell proliferation in vitro.

Journal: JPEN. Journal of parenteral and enteral nutrition20080101

Title: An experimental study of emodin assisted early enteral nutrition for the treatment of severe acute pancreatitis.

Journal: Hepato-gastroenterology20080101

Title: Inhibitory effect of schisandrin B on gastric cancer cells in vitro.

Journal: World journal of gastroenterology20071228

Title: [Comparison of content of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside and anthraquinon in different ploidy Radix Polygoni Multiflori].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20071201

Title: Involvement of endogenous prostaglandin in emodin-evoked rat colonic anion secretion.

Journal: Biological & pharmaceutical bulletin20071101

Title: [Emodin induces leukemic HL-60 cells apoptosis probably by inhibiting Akt signal pathway].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20071101

Title: In situ synthesis of molecularly imprinted polymers on glass microspheres in a column.

Journal: Analytical and bioanalytical chemistry20071001

Title: A new isocoumarin from Hypericum annulatum.

Journal: Natural product research20071001

Title: Effect of vehicles on topical application of aloe vera and arnica montana components.

Journal: Drug delivery20071001

Title: [Study on correlation of soil nutrients and content of active constituents in root of Rumex gmelini].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20071001

Title: Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent.

Journal: Medicinal research reviews20070901

Title: Spectroscopic studies of DNA binding modes of cation-substituted anthrapyrazoles derived from emodin.

Journal: European journal of medicinal chemistry20070901

Title: Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells.

Journal: Carcinogenesis20070901

Title: Quantitation assay for absorption and first-pass metabolism of emodin in isolated rat small intestine using liquid chromatography-tandem mass spectrometry.

Journal: Biological & pharmaceutical bulletin20070901

Title: Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

Journal: Current biology : CB20070821

Title: Silk fibroin mediated delivery of liposomal emodin to breast cancer cells.

Journal: International journal of pharmaceutics20070816

Title: Aloe emodin inhibits the cytotoxic action of tumor necrosis factor.

Journal: European journal of pharmacology20070730

Title: Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats.

Journal: Journal of ethnopharmacology20070725

Title: Emodin, an anthraquinone derivative from Rheum officinale Baill, enhances cutaneous wound healing in rats.

Journal: European journal of pharmacology20070719

Title: Simultaneous determination and pharmacokinetic studies of aloe emodin and chrysophanol in rats after oral administration of Da-Cheng-Qi decoction by high-performance liquid chromatography.

Journal: Biomedical chromatography : BMC20070701

Title: Cellular absorption of anthraquinones emodin and chrysophanol in human intestinal Caco-2 cells.

Journal: Bioscience, biotechnology, and biochemistry20070701

Title: Emodin suppresses interleukin-1beta induced mesangial cells proliferation and extracellular matrix production via inhibiting P38 MAPK.

Journal: Life sciences20070606

Title: Apoptosis-inducing activity of new pyrazole emodin derivatives in human hepatocellular carcinoma HepG2 cells.

Journal: Biological & pharmaceutical bulletin20070601

Title: [Application of macroporous resin in purification for effective part from Polygonum cuspidatum].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20070601

Title: [Advance of study on apoptosis inducer of several types of natural drug].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi20070601

Title: Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb.

Journal: Natural product research20070520

Title: Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction.

Journal: Antiviral research20070501

Title: Synergistic interaction of physcion and chrysophanol on plant powdery mildew.

Journal: Pest management science20070501

Title: Chemical constituents of cape aloe and their synergistic growth-inhibiting effect on Ehrlich ascites tumor cells.

Journal: Bioscience, biotechnology, and biochemistry20070501

Title: Emodin induces growth arrest and death of human vascular smooth muscle cells through reactive oxygen species and p53.

Journal: Journal of cardiovascular pharmacology20070501

Title: Aloe-emodin metabolites protected N-methyl-d-aspartate-treated retinal ganglion cells by Cu-Zn superoxide dismutase.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics20070401

Title: [Comparative study on in vitro drug-release between Tuizhang ophthalmic gel and Tuizhang oculentum].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20070401

Title: Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis.

Journal: Journal of chromatography. A20070323

Title: Emodin induces apoptosis through caspase 3-dependent pathway in HK-2 cells.

Journal: Toxicology20070307

Title: Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.

Journal: Carcinogenesis20070301

Title: Emodin and DHA potently increase arsenic trioxide interferon-alpha-induced cell death of HTLV-I-transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1.

Journal: Blood20070215

Title: Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-Ll cells.

Journal: Biochemical and biophysical research communications20070209

Title: Inhibition of protein kinase CK2 leads to a modulation of androgen receptor dependent transcription in prostate cancer cells.

Journal: The Prostate20070201

Title: Alterations in secondary metabolism of aposymbiotically grown mycobionts of Xanthoria elegans and cultured resynthesis stages.

Journal: Plant physiology and biochemistry : PPB20070201

Title: Photo-irradiation of Aloe vera by UVA--formation of free radicals, singlet oxygen, superoxide, and induction of lipid peroxidation.

Journal: Toxicology letters20070130

Title: Effect of emodin on pancreatic fibrosis in rats.

Journal: World journal of gastroenterology20070121

Title: Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action.

Journal: The international journal of biochemistry & cell biology20070101

Title: Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin.

Journal: Cancer biology & therapy20070101

Title: Determination of the anthraquinones aloe-emodin and aloin-A by liquid chromatography with mass spectrometric and diode array detection.

Journal: Journal of AOAC International20070101

Title: Preparative isolation and purification of hydroxyanthraquinones from Rheum tanguticum Maxim. on normal phase silica gel: using a Flash Master Personal system.

Journal: Preparative biochemistry & biotechnology20070101

Title: Inhibition of human cytochrome p450 1b1 further clarifies its role in the activation of dibenzo[a,l]pyrene in cells in culture.

Journal: Journal of biochemical and molecular toxicology20070101

Title: Lichen secondary metabolites from the cultured lichen mycobionts of Teloschistes chrysophthalmus and Ramalina celastri and their antiviral activities.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20070101

Title: The effect of emodin-assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury.

Journal: Mediators of inflammation20070101

Title: Anthraquinone derivative emodin inhibits tumor-associated angiogenesis through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation.

Journal: European journal of pharmacology20061228

Title: Inhibition of phosphorylation of p38 MAPK involved in the protection of nephropathy by emodin in diabetic rats.

Journal: European journal of pharmacology20061228

Title: Evaluation of the anti-angiogenic effect of aloe-emodin.

Journal: Cellular and molecular life sciences : CMLS20061201

Title: Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1).

Journal: Life sciences20061125

Title: [Effect of preparation on the major chemical constituents of Polygonum multiflorum].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20061001

Title: [Effect of emodin on pancreatic fibrosis: experiment with rats].

Journal: Zhonghua yi xue za zhi20060926

Title: Synthesis, DNA binding and cytotoxicity of new pyrazole emodin derivatives.

Journal: European journal of medicinal chemistry20060901

Title: Inhibition of the replication of hepatitis B virus in vitro by emodin.

Journal: Medical science monitor : international medical journal of experimental and clinical research20060901

Title: Supercritical CO2 extraction of emodin and physcion from Polygonum cuspidatum and subsequent isolation by semipreparative chromatography.

Journal: Journal of separation science20060901

Title: [Induction of hairy roots and anthraquinone production in Rheum palmatum].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060901

Title: Effects of pharmacological preconditioning by emodin/oleanolic acid treatment and/or ischemic preconditioning on mitochondrial antioxidant components as well as the susceptibility to ischemia-reperfusion injury in rat hearts.

Journal: Molecular and cellular biochemistry20060801

Title: Aloe-emodin induced DNA damage through generation of reactive oxygen species in human lung carcinoma cells.

Journal: Cancer letters20060728

Title: [Effect of emodin on NO-cGMP signal pathway in rat vascular endothelium in vitro].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20060701

Title: Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation.

Journal: International journal of cancer20060601

Title: Emodin inhibits tumor cell adhesion through disruption of the membrane lipid Raft-associated integrin signaling pathway.

Journal: Cancer research20060601

Title: [HPLC fingerprint of Rhizoma Polygoni Cuspidati].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060601

Title: [Experimental study on effects of emodin on nonalcoholic fatty liver induced by high fat diet in rats].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.

Journal: The American journal of pathology20060501

Title: [Correlation of anti-bacterial activity with secondary metabolites content in Sargentodoxa Cuneata tables].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences20060501

Title: [Studies on the chemical constituents in stem rind of Wikstroemia indica].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060501

Title: Evaluation of MTT assay for measurement of emodin-induced cytotoxicity.

Journal: Assay and drug development technologies20060401

Title: [Study on the selection of crude drugs of rhubarb dispensing granule].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20060401

Title: Effects of emodin on Ca2+ signal transduction of smooth muscle cells in multiple organ dysfunction syndrome.

Journal: The Journal of surgical research20060301

Title: Role of exon-16-deleted HER2 in breast carcinomas.

Journal: Endocrine-related cancer20060301

Title: [Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20060301

Title: Silk-fibroin-coated liposomes for long-term and targeted drug delivery.

Journal: International journal of nanomedicine20060301

Title: Antidiabetic effects of dietary administration of Aloe arborescens Miller components on multiple low-dose streptozotocin-induced diabetes in mice: investigation on hypoglycemic action and systemic absorption dynamics of aloe components.

Journal: Journal of ethnopharmacology20060220

Title: Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb.

Journal: Bioorganic & medicinal chemistry letters20060201

Title: [Simultaneous determination of resveratrol, emodin, chrysophanol, physcion, in root of Polygonam cuspidatum and its extract by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060201

Title: [Studies on chemical constituents of hairy root of Cassia obtusifolia].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20060201

Title: [Ultracytochemical studies of aloin in Aloe arborescens leaves].

Journal: Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology20060201

Title: Bi-directional regulation of emodin and quercetin on smooth muscle myosin of gizzard.

Journal: FEBS letters20060123

Title: Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification.

Journal: Cancer biology & therapy20060101

Title: Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway.

Journal: The Journal of urology20060101

Title: [Preparative separation of aloin diastereoisomers by high-speed countercurrent chromatography combined with silica gel column chromatography].

Journal: Se pu = Chinese journal of chromatography20060101

Title: Aloe-emodin affects the levels of cytokines and functions of leukocytes from Sprague-Dawley rats.

Journal: In vivo (Athens, Greece)20060101

Title: Determination and locational variations in the quantity of hydroxyanthraquinones and their glycosides in rhizomes of Rheum emodi using high-performance liquid chromatography.

Journal: Journal of chromatography. A20051202

Title: Preparative isolation and purification of five compounds from the Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography.

Journal: Journal of chromatography. A20051202

Title: Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2).

Journal: Melanoma research20051201

Title: [Chemical constituents of the aerial parts of Rhamnus crenatus].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20051201

Title: Birch PR-10c interacts with several biologically important ligands.

Journal: Phytochemistry20051101

Title: Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy20051101

Title: Antimutagenicity and cytotoxicity of the constituents from the aerial parts of Rumex acetosa.

Journal: Biological & pharmaceutical bulletin20051101

Title: Effects of emodin treatment on mitochondrial ATP generation capacity and antioxidant components as well as susceptibility to ischemia-reperfusion injury in rat hearts: single versus multiple doses and gender difference.

Journal: Life sciences20051014

Title: Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds.

Journal: Antiviral research20051001

Title: Evaluation of the antibacterial activity of Ventilago madraspatana Gaertn., Rubia cordifolia Linn. and Lantana camara Linn.: isolation of emodin and physcion as active antibacterial agents.

Journal: Phytotherapy research : PTR20051001

Title: Emodin suppresses hyaluronic acid-induced MMP-9 secretion and invasion of glioma cells.

Journal: International journal of oncology20050901

Title: Antimycobacterial agents from selected Mexican medicinal plants.

Journal: The Journal of pharmacy and pharmacology20050901

Title: [Emodin blocks voltage dependent potassium channels in rat proximal colon smooth muscle cells].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20050901

Title: Separation and determination of four active anthraquinones in Chinese herbal preparations by flow injection-capillary electrophoresis.

Journal: Electrophoresis20050801

Title: [A new isoflavone from Huoxue Yiqi Tang].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050801

Title: Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway.

Journal: Biochemical pharmacology20050715

Title: Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.

Journal: Neuropharmacology20050701

Title: Gene expression alteration during redox-dependent enhancement of arsenic cytotoxicity by emodin in HeLa cells.

Journal: Cell research20050701

Title: [Studies on the chemical constituents in herb of Mentha haplocalyx].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050701

Title: Aloe emodin decreases the ERK-dependent anticancer activity of cisplatin.

Journal: Cellular and molecular life sciences : CMLS20050601

Title: Aloe emodin-induced apoptosis in t-HSC/Cl-6 cells involves a mitochondria-mediated pathway.

Journal: Basic & clinical pharmacology & toxicology20050601

Title: [Study on the optimal harvesting time of Rumex gmelini by analyzing the contents of principal components].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050601

Title: [Influence of processing rhubarb on it's anthraquinone contents].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050601

Title: Effect of emodin on small intestinal peristalsis of mice and relevant mechanism.

Journal: World journal of gastroenterology20050528

Title: Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway.

Journal: Cellular and molecular life sciences : CMLS20050501

Title: Effects of emodin and baicalein on rats with severe acute pancreatitis.

Journal: World journal of gastroenterology20050414

Title: Effects of emodin on treating murine nonalcoholic fatty liver induced by high caloric laboratory chaw.

Journal: World journal of gastroenterology20050307

Title: Release of nucleophosmin from the nucleus: Involvement in aloe-emodin-induced human lung non small carcinoma cell apoptosis.

Journal: International journal of cancer20050301

Title: Anti-glioma action of aloe emodin: the role of ERK inhibition.

Journal: Cellular and molecular life sciences : CMLS20050301

Title: [Influence of process methods on contents of chemical component Radix Polygoni Multiflori].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20050301

Title: [Study on the chemical constituents from Rumex japonicus Houtt].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20050201

Title: Identification of potential biomarkers of genotoxicity and carcinogenicity in L5178Y mouse lymphoma cells by cDNA microarray analysis.

Journal: Environmental and molecular mutagenesis20050101

Title: DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (aloin).

Journal: Cancer biology & therapy20050101

Title: Influence of functional group substitutions on the carcinogenicity of anthraquinone in rats and mice: analysis of long-term bioassays by the National Cancer Institute and the National Toxicology Program.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews20050101

Title: Novel curcumin- and emodin-related compounds identified by in silico 2D/3D conformer screening induce apoptosis in tumor cells.

Journal: BMC cancer20050101

Title: Analysis of the anthraquinones aloe-emodin and aloin by gas chromatography/mass spectrometry.

Journal: International immunopharmacology20041220

Title: Aloe-emodin modulates PKC isozymes, inhibits proliferation, and induces apoptosis in U-373MG glioma cells.

Journal: International immunopharmacology20041220

Title: Anthraquinones sensitize tumor cells to arsenic cytotoxicity in vitro and in vivo via reactive oxygen species-mediated dual regulation of apoptosis.

Journal: Free radical biology & medicine20041215

Title: [Effect of emodin on motility signal transduction in colonic smooth muscle cells in rats with multiple organ dysfunction syndrome].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20041201

Title: Synthesis and biological evaluation of new derivatives of emodin.

Journal: Bioorganic & medicinal chemistry20041115

Title: Aspergillus fumigatus CY018, an endophytic fungus in Cynodon dactylon as a versatile producer of new and bioactive metabolites.

Journal: Journal of biotechnology20041109

Title: Anti-proliferative lichen compounds with inhibitory activity on 12(S)-HETE production in human platelets.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20041101

Title: [Simultaneous determination of 4 anthraquinones in Kuhuang injection by RP-HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20041101

Title: Peroxynitrite scavenging mode of alaternin isolated from Cassia tora.

Journal: The Journal of pharmacy and pharmacology20041001

Title: The stimulant cathartic, emodin, contracts the rat isolated ileum by triggering release of endogenous acetylcholine.

Journal: Autonomic & autacoid pharmacology20041001

Title: Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition.

Journal: Biochemical pharmacology20040915

Title: Alaternin and emodin with hydroxyl radical inhibitory and/or scavenging activities and hepatoprotective activity on tacrine-induced cytotoxicity in HepG2 cells.

Journal: Archives of pharmacal research20040901

Title: [Determination of active anthraquinones in Rheum and its tea preparations by micellar electrokinetic capillary electrophoresis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20040901

Title: [Determination of aloin content in callus of Aloe vera var. chinensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20040901

Title: Aloe-emodin induced in vitro G2/M arrest of cell cycle in human promyelocytic leukemia HL-60 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20040801

Title: Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin.

Journal: Biochemical pharmacology20040801

Title: Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats.

Journal: Journal of hepatology20040801

Title: Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activity.

Journal: Chemical & pharmaceutical bulletin20040801

Title: Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-kappaB.

Journal: Biochemical pharmacology20040715

Title: The lichens Xanthoria elegans and Cetraria islandica maintain a high protection against UV-B radiation in Arctic habitats.

Journal: Oecologia20040701

Title: Aloe-emodin prevents cytokine-induced tumor cell death: the inhibition of auto-toxic nitric oxide release as a potential mechanism.

Journal: Cellular and molecular life sciences : CMLS20040701

Title: [The inhibitive effects of the ethanol extract from Radix et Rhizoma Rhei on the secretion of HBsAg and HBeAg].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20040601

Title: Signal pathways involved in emodin-induced contraction of smooth muscle cells from rat colon.

Journal: World journal of gastroenterology20040515

Title: Inhibition of MAO A and B by some plant-derived alkaloids, phenols and anthraquinones.

Journal: Journal of ethnopharmacology20040401

Title: Rational elimination of Aspergillus terreus sulochrin production.

Journal: Journal of biotechnology20040304

Title: Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors.

Journal: Molecular carcinogenesis20040301

Title: Dicoumarol alters cellular redox state and inhibits nuclear factor kappa B to enhance arsenic trioxide-induced apoptosis.

Journal: Acta biochimica et biophysica Sinica20040301

Title: Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.

Journal: The Journal of biological chemistry20040109

Title: Antisense blocking of BRCA1 enhances sensitivity to plumbagin but not tamoxifen in BG-1 ovarian cancer cells.

Journal: Molecular carcinogenesis20040101

Title: Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling.

Journal: Cancer research20040101

Title: Evaluation of a real-time polymerase chain reaction method for the quantification of CYP1B1 gene expression in MCF-7 human breast carcinoma cells.

Journal: Journal of pharmacological and toxicological methods20040101

Title: Microbial glycosylation of four free anthraquinones by Absidia coerulea.

Journal: Biotechnology letters20040101

Title: Emodin isolated from Cassia obtusifolia (Leguminosae) seed shows larvicidal activity against three mosquito species.

Journal: Journal of agricultural and food chemistry20031217

Title: Tumor necrosis factor-alpha and troglitazone regulate plasminogen activator inhibitor type 1 production through extracellular signal-regulated kinase- and nuclear factor-kappaB-dependent pathways in cultured human umbilical vein endothelial cells.

Journal: The Journal of pharmacology and experimental therapeutics20031201

Title: Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.

Journal: Environmental health perspectives20031201

Title: Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Journal: Biological & pharmaceutical bulletin20031201

Title: Radical-scavenging effects of Aloe arborescens Miller on prevention of pancreatic islet B-cell destruction in rats.

Journal: Journal of ethnopharmacology20031101

Title: [Therapeutic effect of qingyi decoction and tetrandrine in treating severe acute pancreatitis in miniature pigs and serum drug level determination].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20031101

Title: [Relationship between antibacterial activity of aloe and its anthaquinone compounds].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20031101

Title: High-performance liquid chromatographic assay for the determination of Aloe Emodin in mouse plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20031025

Title: Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin.

Journal: International journal of cancer20031010

Title: Micropropagation of Polygonum multiflorum THUNB and quantitative analysis of the anthraquinones emodin and physcion formed in in vitro propagated shoots and plants.

Journal: Biological & pharmaceutical bulletin20031001

Title: [Development of aloin cells and accumulation of anthraquinone in aloe leaf].

Journal: Shi yan sheng wu xue bao20031001

Title: [Phenolic compounds isolated from rhizoma of Aster tataricus].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20031001

Title: Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).

Journal: The Biochemical journal20030915

Title: Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells.

Journal: Leukemia research20030901

Title: Contractile effects and intracellular Ca2+ signalling induced by emodin in circular smooth muscle cells of rat colon.

Journal: World journal of gastroenterology20030815

Title: Cynodontin: a fungal metabolite with antifungal properties.

Journal: Journal of agricultural and food chemistry20030813

Title: Signaling pathway for aloe-emodin-induced apoptosis in human H460 lung nonsmall carcinoma cell.

Journal: International journal of cancer20030810

Title: Emodin ameliorates glucose-induced matrix synthesis in human peritoneal mesothelial cells.

Journal: Kidney international20030801

Title: Sulfemodin 8-O-beta-D-glucoside, a new sulfated anthraquinone glycoside, and antioxidant phenolic compounds from Rheum emodi.

Journal: Journal of natural products20030801

Title: [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20030801

Title: Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9.

Journal: European journal of pharmacology20030725

Title: [Studies on the chemical constituents of Dendrobium fimbriatum].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20030701

Title: Neuraminidase inhibitors from Reynoutria elliptica.

Journal: Archives of pharmacal research20030501

Title: [Studies on the extraction of ingredients from Chinese traditional medicine with CO2 supercritical fluid].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20030501

Title: Capillary electrophoresis for simultaneous determination of emodin, chrysophanol, and their 8-beta-D-glucosides.

Journal: Chemical & pharmaceutical bulletin20030401

Title: [Effect of emodin and apigenin on invasion of human ovarian carcinoma HO-8910PM cells in vitro].

Journal: Ai zheng = Aizheng = Chinese journal of cancer20030401

Title: Is parietin a UV-B or a blue-light screening pigment in the lichen Xanthoria parietina?

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology20030401

Title: Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.

Journal: The EMBO journal20030317

Title: Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3.

Journal: Molecular cancer therapeutics20030301

Title: Transcriptional suppression of the HIV promoter by natural compounds.

Journal: Antiviral research20030301

Title: Determination of active components in rhubarb and study of their hydrophobicity by micellar electrokinetic chromatography.

Journal: Bioorganic & medicinal chemistry letters20030224

Title: Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.

Journal: The Journal of biological chemistry20030117

Title: Inhibition of collagenase and metalloproteinases by aloins and aloe gel.

Journal: Life sciences20030103

Title: Inhibition of azoxymethane-induced DNA adduct formation by Aloe arborescens var. natalensis.

Journal: Asian Pacific journal of cancer prevention : APJCP20030101

Title: Identification of major metabolites in Aloe littoralis by high-performance liquid chromatography-nuclear magnetic resonance spectroscopy.

Journal: Phytochemical analysis : PCA20030101

Title: Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.

Journal: Biochemical pharmacology20021215

Title: Permeation-enhancing effect of aloe-emodin anthrone on water-soluble and poorly permeable compounds in rat colonic mucosa.

Journal: Biological & pharmaceutical bulletin20021201

Title: Aloin, cinnamic acid and sophorcarpidine are potent inhibitors of tyrosinase.

Journal: Chinese medical journal20021201

Title: In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin.

Journal: Planta medica20021101

Title: Inducible nitric oxide synthase inhibitors of Chinese herbs III. Rheum palmatum.

Journal: Planta medica20021001

Title: [Determination of six effective components in Rheum by cyclodextrin modified micellar electrokinetic chromatography].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20021001

Title: The antiproliferative activity of aloe-emodin is through p53-dependent and p21-dependent apoptotic pathway in human hepatoma cell lines.

Journal: Life sciences20020906

Title: Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis.

Journal: Cancer letters20020828

Title: Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis.

Journal: Oncogene20020808

Title: Mechanisms of Chinese herb emodin and somatostatin analogs on pancreatic regeneration in acute pancreatitis in rats.

Journal: Pancreas20020801

Title: Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets.

Journal: Seminars in liver disease20020801

Title: Induction of apoptosis in hepatocellular carcinoma cell lines by emodin.

Journal: Japanese journal of cancer research : Gann20020801

Title: Simultaneous determination of Aloe-emodin and Rhein by synchronous fluorescence spectroscopy.

Journal: Journal of pharmaceutical and biomedical analysis20020720

Title: Studies on the photostability and phototoxicity of aloe-emodin, emodin and rhein.

Journal: Die Pharmazie20020601

Title: [Contents of barbaloin-related compounds in aloe drinks and their change during storage].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan20020601

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Photochemistry and phototoxicity of aloe emodin.

Journal: Photochemistry and photobiology20020401

Title: Aloe emodin suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture.

Journal: Pharmacology & toxicology20020401

Title: [Studies on the chemical constituents in root of Rheum rhizastachyum].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20020401

Title: The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line.

Journal: The American Journal of dermatopathology20020201

Title: [Studies on the chemical constituents of the stems of Alyxia sinensis (I)].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20020201

Title: [Hairy-root culture of Polygonium multiflorum Thunb. and the production of its active constituents-anthraquinones].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology20020101

Title: ErbB2 overexpression in an ovarian cancer cell line confers sensitivity to the HSP90 inhibitor geldanamycin.

Journal: Anticancer research20020101

Title: Toward the rational design of protein kinase casein kinase-2 inhibitors.

Journal: Pharmacology & therapeutics20020101

Title: Cytotoxicity of natural hydroxyanthraquinones: role of oxidative stress.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20020101

Title: Effects of polyphenolic anthrone derivatives, resistomycin and hypercin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20020101

Title: [Study on the quantitative change of anthraquinonoids of Rhei in the preparation of dachengqi].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20020101

Title: Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues.

Journal: Bioorganic & medicinal chemistry letters20011217

Title: Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma.

Journal: European journal of pharmacology20011123

Title: Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole.

Journal: Protein science : a publication of the Protein Society20011101

Title: Protein kinase C involvement in aloe-emodin- and emodin-induced apoptosis in lung carcinoma cell.

Journal: British journal of pharmacology20011101

Title: Hypotensive effect of chemical constituents from Aloe barbadensis.

Journal: Planta medica20011101

Title: Hepatotoxin rubratoxin B induced the secretion of TNF-alpha, IL-8, and MCP-1 in HL60 cells.

Journal: Biochemical and biophysical research communications20011005

Title: Aloe exudate: characterization by reversed phase HPLC and headspace GC-MS.

Journal: Journal of agricultural and food chemistry20011001

Title: [Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth. var. officinalis (Dode) Huang].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20011001

Title: [Studies on chemical constituents of Bletilla striata (Thunb) Reichb. f].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica20011001

Title: Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5.

Journal: Drug metabolism and disposition: the biological fate of chemicals20010901

Title: Effects and mechanisms of emodin on cell death in human lung squamous cell carcinoma.

Journal: British journal of pharmacology20010901

Title: Cytotoxicity of Rhamnosylanthraquinones and Rhamnosylanthrones from Rhamnus nepalensis.

Journal: Journal of natural products20010901

Title: Metabolism of 1,8-dihydroxy 3-hydroxy methyl anthraquinone (aloe-emodin) isolated from the leaves of Cassia tora in albino rats.

Journal: Phytotherapy research : PTR20010801

Title: Generation of free radicals by emodic acid and its [D-Lys6]GnRH-conjugate.

Journal: Photochemistry and photobiology20010801

Title: [Effects of emodin on hepatic fibrosis in rats].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20010801

Title: Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.

Journal: Bioorganic & medicinal chemistry letters20010723

Title: Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.

Journal: The Biochemical journal20010715

Title: [Effect of aloe-emodin on c-myc gene expression of cultured vascular smooth muscle cells of injured artery].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20010701

Title: Effect of aloe-emodin on expression of proliferating cell nuclear antigen of vascular smooth muscle cells in culture after arterial injury.

Journal: Chinese medical journal20010601

Title: [Study on effect of emodin on TGF beta 1 expression in pancreatic tissue of rats suffering from acute pancreatitis].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20010601

Title: Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

Journal: FEBS letters20010504

Title: Cytotoxic principles from Ventilago leiocarpa.

Journal: Journal of natural products20010501

Title: In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus.

Journal: Antiviral research20010301

Title: Immune reponses in human mesangial cells regulated by emodin from Polygonum hypoleucum Ohwi.

Journal: Life sciences20010202

Title: Determination of pKa values of anthraquinone compounds by capillary electrophoresis.

Journal: Electrophoresis20010201

Title: Regulation of cell proliferation, inflammatory cytokine production and calcium mobilization in primary human T lymphocytes by emodin from Polygonum hypoleucum Ohwi.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20010201

Title: Emodin ameliorates glucose-induced morphologic abnormalities and synthesis of transforming growth factor beta1 and fibronectin by human peritoneal mesothelial cells.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis20010101

Title: Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules.

Journal: Proceedings of the National Academy of Sciences of the United States of America19960903

Title: Hydroxyquinones are competitive non-peptide inhibitors of HIV-1 proteinase.

Journal: Biochimica et biophysica acta19951115

Title: Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols.

Journal: Archives of biochemistry and biophysics19951001

Title: Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.

Journal: Drug metabolism and disposition: the biological fate of chemicals19940101

Title: Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus.

Journal: Antiviral research19920101

Title: In vitro virucidal activity of selected anthraquinones and anthraquinone derivatives.

Journal: Antiviral research19910901

518-82-1 | Emodin