Home Pyridines 519-02-8
519-02-8,MFCD00210527
Catalog No.:AA0037N5

519-02-8 | (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0037N5
Chemical Name:
(7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
CAS Number:
519-02-8
Molecular Formula:
C15H24N2O
Molecular Weight:
248.3639
MDL Number:
MFCD00210527
SMILES:
O=C1CCC[C@H]2N1C[C@@H]1CCCN3[C@@H]1[C@@H]2CCC3
NSC Number:
146051
Properties
Properties
 
BP:
396.7°C at 760 mmHg  
Form:
Solid  
MP:
77 C  
Refractive Index:
1,536  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
356  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
1.6  

Literature

Title: Matrine compromises mouse sperm functions by a [Ca(2+)]i-related mechanism.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20160401

Title: Arsenic trioxide-enhanced, matrine-induced apoptosis in multiple myeloma cell lines.

Journal: Planta medica 20130601

Title: Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression.

Journal: Biochemical pharmacology 20130101

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Effects of the Chinese medicine matrine on experimental C. parvum infection in BALB/c mice and MDBK cells.

Journal: Parasitology research 20121001

Title: [Effects of matrine on the proliferation and apoptosis of human rhabdomyosarcoma RD cells].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20121001

Title: Matrine modulates HSC70 levels and rescues ΔF508-CFTR.

Journal: Journal of cellular physiology 20120901

Title: Post-expansile hydrogel foam aerosol of PG-liposomes: a novel delivery system for vaginal drug delivery applications.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830

Title: Antiviral effect of matrine against human enterovirus 71.

Journal: Molecules (Basel, Switzerland) 20120829

Title: Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats.

Journal: The Journal of pharmacy and pharmacology 20120801

Title: Matrine- and oxymatrine-imprinted monodisperse polymers prepared by precipitation polymerization and their applications for the selective extraction of matrine-type alkaloids from Sophora flavescens Aiton.

Journal: Journal of chromatography. A 20120727

Title: Preparation and characterization of magnetic alginate-chitosan hydrogel beads loaded matrine.

Journal: Drug development and industrial pharmacy 20120701

Title: Neuroprotective effect of early and short-time applying sophoridine in pMCAO rat brain: down-regulated TRAF6 and up-regulated p-ERK1/2 expression, ameliorated brain infaction and edema.

Journal: Brain research bulletin 20120701

Title: Comprehensive two-dimensional HepG2/cell membrane chromatography/monolithic column/time-of-flight mass spectrometry system for screening anti-tumor components from herbal medicines.

Journal: Journal of chromatography. A 20120615

Title: Synthesis, characterization and in vitro anti-tumor activities of matrine derivatives.

Journal: Bioorganic & medicinal chemistry letters 20120615

Title: The influence of intraoperative pleural perfusion with matrine-cisplatin or cisplatin on stromal cell-derived factor-1 in non-small cell lung cancer patients with subclinical pleural metastasis.

Journal: Medical oncology (Northwood, London, England) 20120601

Title: Effects of matrine on proliferation and apoptosis of cultured retinoblastoma cells.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120601

Title: Effects of matrine on proliferation and apoptosis in gallbladder carcinoma cells (GBC-SD).

Journal: Phytotherapy research : PTR 20120601

Title: Direct protection of neurons and astrocytes by matrine via inhibition of the NF-κB signaling pathway contributes to neuroprotection against focal cerebral ischemia.

Journal: Brain research 20120515

Title: Inhibition of matrine against gastric cancer cell line MNK45 growth and its anti-tumor mechanism.

Journal: Molecular biology reports 20120501

Title: Matrine inhibits proliferation and induces apoptosis of the androgen‑independent prostate cancer cell line PC-3.

Journal: Molecular medicine reports 20120301

Title: Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2.

Journal: Cancer chemotherapy and pharmacology 20120201

Title: Matrine inhibits disturbed flow-enhanced migration via downregulation of ERK1/2-MLCK signaling vascular smooth muscle cells.

Journal: Annals of vascular surgery 20120201

Title: Oxymatrinium tetra-chloridoferrate(III).

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Subcritical water extraction of alkaloids in Sophora flavescens Ait. and determination by capillary electrophoresis with field-amplified sample stacking.

Journal: Journal of pharmaceutical and biomedical analysis 20120125

Title: Effects and mechanism characterization of ionic liquids as mobile phase additives for the separation of matrine-type alkaloids by liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20120125

Title: Anti-inflammatory effects of active constituents extracted from Chinese medicinal herbs against Propionibacterium acnes.

Journal: Natural product research 20120101

Title: Selective extraction and separation of oxymatrine from Sophora flavescens Ait. extract by silica-confined ionic liquid.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120101

Title: Matrine inhibits pacing induced atrial fibrillation by modulating I(KM3) and I(Ca-L).

Journal: International journal of biological sciences 20120101

Title: Impact of the herbal medicine Sophora flavescens on the oral pharmacokinetics of indinavir in rats: the involvement of CYP3A and P-glycoprotein.

Journal: PloS one 20120101

Title: [Optimization of a compound prescription for treating liver fibrosis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120101

Title: Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials.

Journal: Chinese medicine 20120101

Title: Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats.

Journal: International journal of biological sciences 20120101

Title: Current situation and perspectives of clinical study in integrative medicine in china.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Hepatoprotective effect of Matrine salvianolic acid B salt on Carbon Tetrachloride-Induced Hepatic Fibrosis.

Journal: Journal of inflammation (London, England) 20120101

Title: Comparative analysis of quinolizidine alkaloids from different parts of Sophora alopecuroides seeds by UPLC-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20120101

Title: Understanding the mechanism of hepatic fibrosis and potential therapeutic approaches.

Journal: Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20120101

Title: Matrine inhibits breast cancer growth via miR-21/PTEN/Akt pathway in MCF-7 cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Antitumor activities of kushen: literature review.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Alkaloids isolated from natural herbs as the anticancer agents.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation.

Journal: PloS one 20120101

Title: Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111218

Title: [Alcohol-purification technology and its particle sedimentation process in manufactory of Fufang Kushen injection].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101

Title: [Meta analysis of compound matrine injection combined with cisplatin chemotherapy for advanced gastric cancer].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111101

Title: [TF-1 cell apoptosis-inducing effect of matrine and its effect on SALL4 expression].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111001

Title: Synthesis, structure-activity relationship and biological evaluation of novel N-substituted matrinic acid derivatives as host heat-stress cognate 70 (Hsc70) down-regulators.

Journal: Bioorganic & medicinal chemistry letters 20110815

Title: Matrine attenuates endotoxin-induced acute liver injury after hepatic ischemia/reperfusion in rats.

Journal: Surgery today 20110801

Title: Molecularly imprinted solid-phase extraction of matrine from radix Sophorae tonkinensis.

Journal: The Analyst 20110721

Title: Autophagy is involved in anticancer effects of matrine on SGC-7901 human gastric cancer cells.

Journal: Oncology reports 20110701

Title: The negative inotropic effects of homocysteine were prevented by matrine via the regulating intracellular calcium level.

Journal: International journal of cardiology 20110701

Title: Differential function of protective agents at each stage of the hypothermic preservation of hepatocytes.

Journal: Journal of biochemistry 20110601

Title: [Simultaneous determination of 7 alkaloid in herba Sophorae Alopecuroidis by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601

Title: In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait.

Journal: Basic & clinical pharmacology & toxicology 20110501

Title: Studies on the dynamic accumulations of Sophora alopecuroides L. Alkaloids in different harvest times and the appropriate harvest time.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501

Title: [Study on matrine alleviating retinoic acid resistance in acute promyelocytic leukemia].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501

Title: A novel solid-state electrochemiluminescence detector for capillary electrophoresis based on tris(2,2'-bipyridyl)ruthenium(II) immobilized in Nafion/PTC-NH2 composite film.

Journal: Talanta 20110415

Title: Matrine-imprinted monolithic stationary phase for extraction and purification of matrine from Sophorae flavescentis Ait.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415

Title: [Inhibitory effect of pyrrolidine dithiocarbamate combined with matrine on the growth of human hepatocellular carcinoma xenografts].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20110401

Title: [Effect and mechanism of matrine on apoptosis of Raji cells].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110401

Title: Matrine inhibits matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells.

Journal: Journal of Asian natural products research 20110301

Title: [Studies on key processes of Fufang Kushen injection].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110301

Title: Design and synthesis of oxymatrine analogues overcoming drug resistance in hepatitis B virus through targeting host heat stress cognate 70.

Journal: Journal of medicinal chemistry 20110210

Title: Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga(III), Au(III), Sn(IV) ions, and DNA binding studies.

Journal: Journal of inorganic biochemistry 20110201

Title: Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Network target for screening synergistic drug combinations with application to traditional Chinese medicine.

Journal: BMC systems biology 20110101

Title: Matrine suppresses production of IL-23/IL-17 and ameliorates experimental autoimmune encephalomyelitis.

Journal: The American journal of Chinese medicine 20110101

Title: Macrophage autophagy and oxidative stress: an ultrastructural and immunoelectron microscopical study.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway.

Journal: Journal of experimental & clinical cancer research : CR 20110101

Title: Hepatoprotective and antioxidant effects of licorice extract against CCl₄-induced oxidative damage in rats.

Journal: International journal of molecular sciences 20110101

Title: Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Effects of matrine and oxymatrine on catalytic activity of cytochrome p450s in rats.

Journal: Basic & clinical pharmacology & toxicology 20101101

Title: Effect of sophoridine on dextran sulfate sodium-induced colitis in C57BL/6 mice.

Journal: Journal of Asian natural products research 20101101

Title: Effect of matrine on human ether à go-go related gene (HERG) channels expressed in Chinese hamster ovary cells.

Journal: Chinese journal of integrative medicine 20101001

Title: Matrine inhibits vascular smooth muscle cell proliferation by modulating the expression of cell cycle regulatory genes.

Journal: Acta pharmacologica Sinica 20101001

Title: Antitumor effect of matrine in human hepatoma G2 cells by inducing apoptosis and autophagy.

Journal: World journal of gastroenterology 20100914

Title: Alkaloids from Sophora flavescens Aition.

Journal: Fitoterapia 20100901

Title: Preparation and in vitro evaluation of ethosomal total alkaloids of Sophora alopecuroides loaded by a transmembrane pH-gradient method.

Journal: AAPS PharmSciTech 20100901

Title: [Toxicity of matrine in Kunming mice].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100901

Title: [Simultaneous determination of five active components in compound preparation of Dangguishuan by high-performance liquid chromatography].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901

Title: Simultaneous stacking of cationic and anionic compounds in single run capillary zone electrophoresis by two-end field amplified sample injection.

Journal: Journal of chromatography. A 20100827

Title: A new A431/cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening epidermal growth factor receptor antagonists from Radix sophorae flavescentis.

Journal: Journal of chromatography. A 20100806

Title: Separation of flavonoid and alkaloid using collagen fiber adsorbent.

Journal: Journal of separation science 20100801

Title: [Pharmacokinetics and bioavailability of sustained-release tablets of matrine in dogs].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801

Title: Matrine induces apoptosis of human multiple myeloma cells via activation of the mitochondrial pathway.

Journal: Leukemia & lymphoma 20100701

Title: [Inhibitory effect of matrine on proliferation of human ovary malignant teratoma cell line PA-1 in vitro].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100701

Title: [Determination of matrine in Fufang Shen'an granules by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701

Title: [Effect of ceftiofur hydrochloride on pharmacokinetics of matrine in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701

Title: [Simultaneous determination of berberine, palmatine, matrine, catechin and baicalin in Funing Shuan by micellar electrokinetic capillary chromatography-electrospray ionization mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20100701

Title: [Determination of matrine in matrine injection by microfluidic chip with contactless conductivity detection].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100701

Title: Matrine inhibits 3T3-L1 preadipocyte differentiation associated with suppression of ERK1/2 phosphorylation.

Journal: Biochemical and biophysical research communications 20100604

Title: In situ gelling gelrite/alginate formulations as vehicles for ophthalmic drug delivery.

Journal: AAPS PharmSciTech 20100601

Title: Solid-phase extraction of matrine and oxymatrine from Sophora Flavescens Ait using amino-imidazolium polymer.

Journal: Journal of separation science 20100601

Title: [Effect of Matrine on cell cycle and human telomerase reverse transcriptase of human salivary adenoid cystic carcinoma].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20100601

Title: Preparation and recognition performance of cytisine alkaloid-imprinted material prepared using novel surface molecular imprinting technique.

Journal: Journal of separation science 20100501

Title: [Study on pharmacokinetics of matrine by intramuscular administration in rat].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100501

Title: [Suppressive effect of matrine on cell growth and decreases beta-catenin-dependent transcriptional activity in hepatoma cell line Hep3B].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100501

Title: Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method.

Journal: Journal of pharmaceutical and biomedical analysis 20100406

Title: Cardioprotective effect of matrine on isoproterenol-induced cardiotoxicity in rats.

Journal: The Journal of pharmacy and pharmacology 20100401

Title: [Comparison of ingredients between two water extractions of danggui kushen pills with or without solid-state fermentation].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401

Title: Multi-walled carbon nanotubes and Ru(bpy)3(2+)/nano-Au nano-sphere as efficient matrixes for a novel solid-state electrochemiluminescence sensor.

Journal: Talanta 20100315

Title: Effects of matrine on HepG2 cell proliferation and expression of tumor relevant proteins in vitro.

Journal: Pharmaceutical biology 20100301

Title: Preparation and evaluation of self-nanoemulsified drug delivery systems (SNEDDSs) of matrine based on drug-phospholipid complex technique.

Journal: International journal of pharmaceutics 20100215

Title: Matrine induces cell anergy in human Jurkat T cells through modulation of mitogen-activated protein kinases and nuclear factor of activated T-cells signaling with concomitant up-regulation of anergy-associated genes expression.

Journal: Biological & pharmaceutical bulletin 20100101

Title: [Epileptic seizure-like effect of Sophora alkaloid sophoridine on experimental animals].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100101

Title: Total alkaloids of Sophora alopecuroides increases the expression of CD4+ CD25+ Tregs and IL-10 in rats with experimental colitis.

Journal: The American journal of Chinese medicine 20100101

Title: Preparation of RGD-modified long circulating liposome loading matrine, and its in vitro anti-cancer effects.

Journal: International journal of medical sciences 20100101

Title: Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines.

Journal: Chinese medicine 20100101

Title: Matrine inhibits proliferation and induces apoptosis of pancreatic cancer cells in vitro and in vivo.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Therapeutic effects of matrine on primary and metastatic breast cancer.

Journal: The American journal of Chinese medicine 20100101

Title: Tissue culture and generation of autotetraploid plants of Sophora flavescens Aiton.

Journal: Pharmacognosy magazine 20100101

Title: Subacute fulminant hepatic failure with intermittent fever.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20091201

Title: Neuroprotective effects of an alkaloid-free ethyl acetate extract from the root of Sophora flavescens Ait. against focal cerebral ischemia in rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20091101

Title: Matrine improves 17alpha-ethinyl estradiol-induced acute cholestasis in rats.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20091101

Title: Extremely large volume electrokinetic stacking of cationic molecules in MEKC by EOF modulation with strong acids in sample solutions.

Journal: Analytical chemistry 20091101

Title: [The effect of matrine on the signal transduction pathway of transforming growth factor-beta1 in human lung fibroblast cells].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20091101

Title: Matrine determination and pharmacokinetics in human plasma using LC/MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Title: [Changes and mechanism of apoptosis-related gene expression in T lymphocytic leukemia JM cells induced with matrine].

Journal: Zhongguo shi yan xue ye xue za zhi 20091001

Title: Impact of matrine on inflammation related factors in rat intestinal microvascular endothelial cells.

Journal: Journal of ethnopharmacology 20090925

Title: Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine.

Journal: Chemico-biological interactions 20090914

Title: Antiarrhythmic properties of long-term treatment with matrine in arrhythmic rat induced by coronary ligation.

Journal: Biological & pharmaceutical bulletin 20090901

Title: [Effects of Hax-1 siRNA on sensitivity to chemotherapy of melanoma A375 cells].

Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090901

Title: [Effect and mechanism of matrine on adhesion and invasion of salivary gland adenoid cystic carcinoma cells in vitro].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20090801

Title: [In vitro activity of matrine against Candida albicans biofilms].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20090801

Title: Relaxant effects of matrine on aortic smooth muscles of guinea pigs.

Journal: Biomedical and environmental sciences : BES 20090801

Title: [The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration of Human Umbilical Veins Endothelial Cells Induced by Lung Cancer cells.].

Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20090720

Title: Chemoprevention of lung squamous cell carcinoma in mice by a mixture of Chinese herbs.

Journal: Cancer prevention research (Philadelphia, Pa.) 20090701

Title: [Matrine enhances the cytotoxic sensitivity of ABCG2high nasopharyngeal carcinoma cells to natural killer cells by inducing high expression of NKG2D receptor ligands].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090701

Title: [Lamivudine, interferon-alpha and oxymatrine treatment for the surviving hepatic failure patients with hepatitis B].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090701

Title: Separation and mechanism elucidation for six structure-like matrine-type alkaloids by micellar liquid chromatography.

Journal: Journal of separation science 20090601

Title: [Effects of matrine on proliferation and telomerase activity of colon cancer SW1116 cells].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090601

Title: [Apoptosis of U937 cell line promoted by matrine through MAPK signal transduction pathway].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601

Title: Matrine induces apoptosis in gastric carcinoma cells via alteration of Fas/FasL and activation of caspase-3.

Journal: Journal of ethnopharmacology 20090504

Title: Hydration, erosion, and release behavior of guar-based hydrophilic matrix tablets containing total alkaloids of Sophora alopecuroides.

Journal: Drug development and industrial pharmacy 20090501

Title: Matrine induces programmed cell death and regulates expression of relevant genes based on PCR array analysis in C6 glioma cells.

Journal: Molecular biology reports 20090401

Title: Physiologically based pharmacokinetics of matrine in the rat after oral administration of pure chemical and ACAPHA.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090401

Title: Comparative effects of sophocarpine and sophoridine on hERG K+ channel.

Journal: European journal of pharmacology 20090401

Title: Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration.

Journal: Cytotechnology 20090401

Title: Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling.

Journal: Cytotechnology 20090401

Title: [Effects of matrine on airway inflammation and early airway remodeling in asthmatic mice].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090301

Title: [Study on pharmacokinetics and tissue distribution of stealth matrine liposomes in rats].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090301

Title: Determination of oxymatrine and its metabolite matrine in rat blood and dermal microdialysates by high throughput liquid chromatography/tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20090220

Title: Wax-matrix tablet for time-dependent colon-specific delivery system of sophora flavescens Aiton: preparation and in vivo evaluation.

Journal: Drug development and industrial pharmacy 20090201

Title: Herbal plants as a promising source of natural antifoulants: evidence from barnacle settlement inhibition.

Journal: Biofouling 20090101

Title: Hepatoprotective effects of marine and kuhuang in liver transplant recipients.

Journal: The American journal of Chinese medicine 20090101

Title: Preparation of matrine ethosome, its percutaneous permeation in vitro and anti-inflammatory activity in vivo in rats.

Journal: Journal of liposome research 20090101

Title: Chinese medicines as a resource for liver fibrosis treatment.

Journal: Chinese medicine 20090101

Title: Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action.

Journal: Molecular cancer 20090101

Title: Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice.

Journal: International immunopharmacology 20081220

Title: Actions of quinolizidine alkaloids on Periplaneta americana nicotinic acetylcholine receptors.

Journal: Pest management science 20081201

Title: Inhibitory effect of matrine on the expression of PSA and AR in prostate cancer cell line LNCaP.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20081201

Title: Inotropic effects and mechanisms of matrine, a main alkaloid from Sophora flavescens AIT.

Journal: Biological & pharmaceutical bulletin 20081101

Title: [Effects of matrine on invasion and metastasis of leukemia cell line Jurkat].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081001

Title: [Effect of pectins of different degree of esterification on in-vitro sophoridine release of hydrophilic matrix tablets containing total alkaloids of Sophora alopecuroides].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

Title: [Effect of matrine and oxymatrine on proliferation and expression of Stat3 and Stat5 in SMMC-7721 cell line].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081001

Title: [Effects of matrine on the growth inhibition, c-myc and hTERT protein expression in human adenocarcinoma lung cancer cell line A549.].

Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20080820

Title: Pharmacokinetic study of matrine, oxymatrine and oxysophocarpine in rat plasma after oral administration of Sophora flavescens Ait. extract by liquid chromatography tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20080805

Title: [Matrine inhibits the proliferation of prostate cancer cells and the activity of androgen receptor].

Journal: Zhonghua nan ke xue = National journal of andrology 20080801

Title: [Simultaneous determination of matrine, oxysophocarpin and oxymatrine in rat plasma by HPLC-MS and its application in the pharmacokinetic study].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080801

Title: [Matrine's inhibitory effect on apoptosis of cardiomyocytes induced by coxsackie virus B(3) and on calcium overload].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20080801

Title: [Effects of matrine, 5-fluorouracil and cisplatin on the expression of APRIL in hepatocellular carcinoma HepG2 cells].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080701

Title: [Effects of matrine on cgi-100 gene expression and proliferation in K562 cells].

Journal: Zhongguo shi yan xue ye xue za zhi 20080601

Title: [Analysis of matrine and oxymatrine in Kushensu injection by UPLC/Q-TOF-MS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601

Title: [Screening on alkaloid of Sophora alopecuraides against adenocarcinoma of colon cell line SW620 in vitro].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080601

Title: Matrine inhibits invasiveness and metastasis of human malignant melanoma cell line A375 in vitro.

Journal: International journal of dermatology 20080501

Title: [Apoptotic mechanism of gastric carcinoma cells induced by matrine injection].

Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20080501

Title: [Effects of matrine on oncogenicity of H22 cells modified by TIM2 gene in vivo].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501

Title: [Matrine inhibits the proliferation of neuroblastoma LA-N-5 cell and MYCN mRNA expression].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080401

Title: [Enhancing effect of matrine on the tumor-inhibition by TIM2 gene-modified hepatocarcinoma H22 cells in mice].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080401

Title: Analysis of quinolizidine alkaloids in Sophora flavescens Ait. by capillary electrophoresis with tris(2,2'-bipyridyl) ruthenium (II)-based electrochemiluminescence detection.

Journal: Talanta 20080315

Title: [Matrine-induced apoptosis in human colon adenocarcinoma SW620 cells].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301

Title: [Matrine-induced erythroid differentiation of K562 cells is associated with activation of the apoptotic pathway].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301

Title: Yessotoxins, a group of marine polyether toxins: an overview.

Journal: Marine drugs 20080301

Title: [Matrine and anti-tumor drugs in inhibiting the growth of human lung cancer cell line].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080201

Title: Anticancer effects of the Chinese medicine matrine on murine hepatocellular carcinoma cells.

Journal: Planta medica 20080201

Title: [Effects of matrine on the apoptosis and expression of adhesion molecule in multiple myeloma RMPI8226 cells].

Journal: Zhongguo shi yan xue ye xue za zhi 20080201

Title: Synergistic action between jasmonic acid and nitric oxide in inducing matrine accumulation of Sophora flavescens suspension cells.

Journal: Journal of integrative plant biology 20080101

Title: Chinese herb related molecules of cancer-cell-apoptosis: a minireview of progress between Kanglaite injection and related genes.

Journal: Journal of experimental & clinical cancer research : CR 20080101

Title: Matrine inhibits PMA-induced MMP-1 expression in human dermal fibroblasts.

Journal: BioFactors (Oxford, England) 20080101

Title: Induced differentiation of hepatocellular carcinoma by natural products.

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20080101

Title: [Inhibition of NF-kappa B activity enhanced apoptosis induced by matrine in hepatocellular carcinoma cells].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20071201

Title: [Simultaneous determination of contents of sophoridine, oxymatrine and oxysophocarpine in seed of Sophora alopecuroides by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

Title: [Preparation of total matrine controlled release micropellet capsules].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071201

Title: [The expression of IER3IP1 gene in K562 cells treated by matrine and its effect on the cell growth].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20071201

Title: [Study on the preparation of matrine-containing nanocell].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071001

Title: [Influence of H2O2 on degradation of residual pesticides and constituents in Radix Sophorae Flavescentis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071001

Title: Matrine inhibits the activity of translation factor eIF4E through dephosphorylation of 4E-BP1 in gastric MKN45 cells.

Journal: Planta medica 20070901

Title: [Studies on cutaneous permeation in vitro of Kushen recipe gel].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070901

Title: Simultaneous determination and pharmacokinetic study of oxymatrine and matrine in beagle dog plasma after oral administration of Kushen formula granule, oxymatrine and matrine by LC-MS/MS.

Journal: Biomedical chromatography : BMC 20070801

Title: Sensitive quantitative determination of oxymatrine and matrine in rat plasma by capillary electrophoresis with stacking induced by moving reaction boundary.

Journal: Analytica chimica acta 20070702

Title: Simultaneous quantification of oxysophocarpine and its active metabolite sophocarpine in rat plasma by liquid chromatography/mass spectrometry for a pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20070701

Title: Matrine induces apoptosis in angiotensin II-stimulated hyperplasia of cardiac fibroblasts: effects on Bcl-2/Bax expression and caspase-3 activation.

Journal: Basic & clinical pharmacology & toxicology 20070701

Title: [Preparation and in vivo evaluation of pH and time dependent Yuchangning tablets for colon-specific delivery].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070701

Title: [Effect of matrine injections on invasion and metastasis of gastric carcinoma SGC-7901 cells in vitro].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070701

Title: Effect of matrine on HeLa cell adhesion and migration.

Journal: European journal of pharmacology 20070601

Title: LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts.

Journal: Biomedical chromatography : BMC 20070601

Title: Effect of matrine on the expression of substance P receptor and inflammatory cytokines production in human skin keratinocytes and fibroblasts.

Journal: International immunopharmacology 20070601

Title: [Experiment research on preventive effect of matrine on rat chronic nephrotoxicity induced by cyclosporin A].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070601

Title: Antifeedant activity and acute and residual toxicity of alkaloids from Sophora flavescens (leguminosae) against formosan subterranean termites (Isoptera: Rhinotermitidae).

Journal: Journal of economic entomology 20070601

Title: [Apoptosis of multiple myeloma RPMI8226 cell line induced by matrine].

Journal: Zhongguo shi yan xue ye xue za zhi 20070601

Title: NACE-ESI-MS combined with on-line concentration for high-sensitivity analysis of quinolizidine alkaloids.

Journal: Electrophoresis 20070501

Title: [Effects of baicalin and other Chinese herbal monomer on androgen receptor mRNA expression in SZ95 sebocytes].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20070401

Title: Supercritical fluid extraction of quinolizidine alkaloids from Sophora flavescens Ait. and purification by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20070323

Title: Matrine upregulates the cell cycle protein E2F-1 and triggers apoptosis via the mitochondrial pathway in K562 cells.

Journal: European journal of pharmacology 20070322

Title: Protective effect of glycyrrhizin, glycyrrhetic acid and matrine on acute cholestasis induced by alpha-naphthyl isothiocyanate in rats.

Journal: Planta medica 20070201

Title: Protective effect of glycyrrhizin and matrine on acute vanishing bile duct syndrome induced by alpha-naphthylisothiocyanate in rats.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20070201

Title: [Matrine-induced gamma-globin synthesis in K562 cells].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070201

Title: [Determination of matrine, sophoridine and oxymatrine in Compound Kushen Injection by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070201

Title: [Effects of matrine, oxymatrine and resveratrol on HERG channel expression].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070201

Title: Matrine induced gastric cancer MKN45 cells apoptosis via increasing pro-apoptotic molecules of Bcl-2 family.

Journal: Toxicology 20070118

Title: [Optimization of preparation for matrine-loaded magnetic chitosan microspheres].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101

Title: [HPCE determination of matrine in matrine liposome].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101

Title: [Inducement effect of matrine on phenotype changes of rat hepatic oval cells].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20061201

Title: A rapid reversed phase high-performance liquid chromatographic method for determination of sophoridine in rat plasma and its application to pharmacokinetics studies.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020

Title: [An approach to the mechanism of matrine and albendazole against Echinococcus multilocularis infection in mice].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20061001

Title: [Inhibition of extracts from 17 Chinese herbs on periodontal pathogenic microbes].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20060801

Title: [Clinical observation on treatment of 75 mid-late stage cancer patients with yanshu Injection].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060801

Title: [Effects of matrine on proliferation and apoptosis of human renal cell carcinoma cell line GRC-1].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060701

Title: [The effects of matrine on cell proliferation and telomerase activity in retinoblastoma cells in vitro].

Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060701

Title: Determination and pharmacokinetic study of oxymatrine and its metabolite matrine in human plasma by liquid chromatography tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20060607

Title: Determination of quinolizidine alkaloids in Sophora flavescens and its preparation using capillary electrophoresis.

Journal: Biomedical chromatography : BMC 20060501

Title: Matrine-induced apoptosis in leukemia U937 cells: involvement of caspases activation and MAPK-independent pathways.

Journal: Planta medica 20060501

Title: [Constituents in the alkaloid fraction of Kushen decoction].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060401

Title: Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats.

Journal: Life sciences 20060320

Title: Matrine improves 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice.

Journal: Pharmacological research 20060301

Title: (+)-12alpha-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescens.

Journal: Bioorganic & medicinal chemistry letters 20060301

Title: Effect of matrine and carvedilol on collagen and MMPs activity of hypertrophy myocardium induced by pressure overload.

Journal: Journal of Zhejiang University. Science. B 20060301

Title: [Inhibition of invasiveness and expression of heparanase-mRNA in human malignant melanoma cell line A375 by matrine].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060301

Title: Using LC/MS/MS to determine matrine, oxymatrine, ferulic acid, mangiferin, and glycyrrhizin in the Chinese medicinal preparations Shiau-feng-saan and Dang-guei-nian-tong-tang.

Journal: Journal of pharmaceutical and biomedical analysis 20060213

Title: [Experimental study on effect of matrine in alleviating renal tubulointerstitial fibrosis in unilateral ureteral obstruction model].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060201

Title: [Effects of Matrine Injection on T-lymphocyte subsets of patients with malignant tumor after gamma knife radiosurgery].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060101

Title: [Study of matrine's use on the reversion of obtained multi-drug resistance of mice S80 tumour cell].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060101

Title: Molecular mechanism of matrine-induced apoptosis in leukemia K562 cells.

Journal: The American journal of Chinese medicine 20060101

Title: [Study on electrochemical kinetics of matrine and sophoridine in a physiological medium].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

Title: [The interference in correlated molecular mechanism obtained multi-drug resistance of mouse S180's tumour cell for different alkaloid].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201

Title: Physicochemical characterization of the Strychnos alkaloids by capillary zone electrophoresis.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051101

Title: [Effect of matrine on regulating renal tubulointerstitial expression of MMP-3, TIMP-1 and FN].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101

Title: Anti-hepatoma effect of arsenic trioxide on experimental liver cancer induced by 2-acetamidofluorene in rats.

Journal: World journal of gastroenterology 20051014

Title: A sensitive and specific HPLC-MS method for the determination of sophoridine, sophocarpine and matrine in rabbit plasma.

Journal: Analytical and bioanalytical chemistry 20050801

Title: Activities of fresh juice of Scutellaria barbata and warmed water extract of Radix Sophorae Tonkinensis on anti-proliferation and apoptosis of human cancer cell lines.

Journal: International journal of molecular medicine 20050801

Title: [HPLC-electrospray ionization ion trap tandem mass spectrometry analysis of oxymatrine and its metabolites in rat urine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050801

Title: [Clinical study of matrine injection on preventing liver function damage of anti-tumor drugs during chemotherapy of breast cancer].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050801

Title: [Clinical study on effect of matrine injection to protect the liver function for patients with primary hepatic carcinoma after trans-artery chemo-embolization (TAE)].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050701

Title: [Apoptosis of human oral epidermoid carcinoma KB cells and multidrug resistant KBv200 cells induced by matrine].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20050601

Title: [Inhibition of tumor growth in tumor-bearing mice treated with matrine].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050601

Title: Implication of the descending dynorphinergic neuron projecting to the spinal cord in the (+)-matrine- and (+)-allomatrine-induced antinociceptive effects.

Journal: Biological & pharmaceutical bulletin 20050501

Title: [Study on direct electrochemical behaviors and the electroanalytical method of matrine type alkaloids at glassy carbon electrode].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050501

Title: Simultaneous determination of oxymatrine and its active metabolite matrine in dog plasma by liquid chromatography-mass spectrometry and its application to pharmacokinetic studies.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325

Title: The involvement of central cholinergic system in (+)-matrine-induced antinociception in mice.

Journal: Pharmacology, biochemistry, and behavior 20050301

Title: [Study on inhibitory effect of matrine on cyclooxygenase-2 expression in colon cancer HT-29 cell line].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050301

Title: [Determination of sophoramine by spectrofluorimetry].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050201

Title: Anti-HBV effect of liposome-encapsulated matrine in vitro and in vivo.

Journal: World journal of gastroenterology 20050121

Title: [Pharmacokinetics of oxymatrine and its metabolite in beagle dogs by LC-MS].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101

Title: Synergistic effects of matrine and 5-fluorouracil on tumor growth of the implanted gastric cancer in nude mice.

Journal: Chinese journal of digestive diseases 20050101

Title: [Studies on fingerprint spectrum of Radix Sophorae Tonkinensis from Guangxi].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050101

Title: Determination of quinolizidine alkaloids in Sophora tonkinensis by HPCE.

Journal: Phytochemical analysis : PCA 20050101

Title: Liquid chromatography of active principles in Sophora flavescens root.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041205

Title: High-performance liquid chromatographic method for simultaneous determination of sophoridine and matrine in rat plasma.

Journal: Biomedical chromatography : BMC 20041101

Title: [Observation of pathological morphology on nervous system of rat with maximum dose sophoridine in chronic toxic test].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20041101

Title: [The effect of matrine on the expression of P170 LRP and TOPO II of obtained multi-drug resistance of mouse S180's tumour cell].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20041101

Title: [Renoprotective effects of matrine on experimental glomerulosclerosis in rats].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20041001

Title: Gas chromatography-mass spectrometry determination of matrine in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905

Title: [Comparison of the anti-arrhythmic effects of matrine and berbamine with amiodarone and RP58866].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040901

Title: [Comparative analysis on effective compositions from tissue-cultured and wild Sophora tonkinensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040801

Title: [Gene expression profile in early differentiation of K562 cells induced by matrine].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040601

Title: [Inhibition of proliferation and influence of proto-oncogenes expression by matrine in C6 cell].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040601

Title: Separation and determination of aloperine, sophoridine, matrine and oxymatrine by combination of flow injection with microfluidic capillary electrophoresis.

Journal: Talanta 20040528

Title: Simultaneous determination of matrine, sophoridine and oxymatrine in Sophora flavescens Ait. by high performance liquid chromatography.

Journal: Biomedical chromatography : BMC 20040401

Title: Efficacy of intramuscular matrine in the treatment of chronic hepatitis B.

Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20040201

Title: [Progress of the study on effective integredients from Chinese herbal medicine in anti-tumor metastasis].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201

Title: [Recent research progress of anti-tumor mechnism matrine].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040201

Title: [Techniques of diseases, insect pests and weeds control and their efficacy in bio-rational rice production].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20040101

Title: [Advance in the pharmacological research on matrine].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030901

Title: [Study on the fingerprints of the alkaloids in Sophora flavescens].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030901

Title: [Study on invasion and metastasis related factors in differentiation of SMMC-7721 cells induced by matrine].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030801

Title: [Matrine effects on JM cells by inhibiting proliferation and inducing apoptosis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030501

Title: Determination of matrine in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies.

Journal: Talanta 20030410

Title: Antinociceptive effects of N-acyloctahydropyrido[3,2,1-ij][1,6]naphthyridine in mice: structure-activity relation study of matrine-type alkaloids part II.

Journal: Biological & pharmaceutical bulletin 20030301

Title: TCM treatment of extrasystole with huanglian shengmai yin--a report of 357 cases.

Journal: Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20030301

Title: Effect of matrine on cold ischemia and reperfusion injury of sinusoidal endothelial cells in rat orthotopic liver transplantation.

Journal: Acta pharmacologica Sinica 20030201

Title: Preparative separation and determination of matrine from the Chinese medicinal plant Sophora flavescens Ait by molecularly imprinted solid-phase extraction.

Journal: Analytical and bioanalytical chemistry 20030101

Title: Matrine protects sinusoidal endothelial cells from cold ischemia and reperfusion injury in rat orthotopic liver transplantation.

Journal: Annals of clinical and laboratory science 20030101

Title: Radix Sophorae flavescentis for chronic hepatitis B: a systematic review of randomized trials.

Journal: The American journal of Chinese medicine 20030101

Title: Movement disorders possibly induced by traditional chinese herbs.

Journal: European neurology 20030101

Title: Effect of matrine on Kupffer cell activation in cold ischemia reperfusion injury of rat liver.

Journal: World journal of gastroenterology 20021215

Title: [Effects of matrine on the activity of protein tyrosine kinase and phosphatase in K562 cells].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20021201

Title: [The influence of Matrine on apoptosis of fibroblasts and the expression of apoptotic modulation related protein in hypertrophic scar of rabbit ear].

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20021001

Title: Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: structure-activity relation study of matrine-type alkaloids.

Journal: Biological & pharmaceutical bulletin 20020801

Title: Determination of matrine and oxymatrine in Sophora subprostata by CE.

Journal: Journal of pharmaceutical and biomedical analysis 20020601

Title: [Matrine affects early expression of proto-oncogenes in K562 cells].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20020401

Title: Current studies on anti-endotoxic chemical components of traditional Chinese medicine in China.

Journal: Acta pharmacologica Sinica 20011201

Title: Indolizidine and quinolizidine alkaloids.

Journal: Natural product reports 20011001

Title: Effects of Matrine on proliferation and differentiation in K-562 cells.

Journal: Leukemia research 20010901

Title: Matrine inhibits production and actions of fibrogenic cytokines released by mouse peritoneal macrophages.

Journal: Acta pharmacologica Sinica 20010801

Title: [Effects of matrine on the relative molecules expression of proliferation and apoptosis in K562 cells].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20010801

Title: Effects of matrine, artemisinin, tetrandrine on cytosolic [Ca2+]i in guinea pig ventricular myocytes.

Journal: Acta pharmacologica Sinica 20010601

Title: [Studies on metabolism of oxymatrine by human intestinal bacteria].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010401

Title: Antifibrotic effects of matrine on in vitro and in vivo models of liver fibrosis in rats.

Journal: Acta pharmacologica Sinica 20010201

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Tags:519-02-8 Molecular Formula|519-02-8 MDL|519-02-8 SMILES|519-02-8 (7aS,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one