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528-71-2,MFCD00059692
Catalog No.:AA003ECD

528-71-2 | 1-Hydroxyphenazine

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25mg
≥98%
in stock  
$50.00   $35.00
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50mg
≥98%
in stock  
$96.00   $67.00
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100mg
≥98%
in stock  
$130.00   $91.00
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1g
>95.0%(HPLC)
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$738.00   $517.00
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5g
>95.0%(HPLC)
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$2,366.00   $1,657.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003ECD
Chemical Name:
1-Hydroxyphenazine
CAS Number:
528-71-2
Molecular Formula:
C12H8N2O
Molecular Weight:
196.2047
MDL Number:
MFCD00059692
SMILES:
Oc1cccc2c1nc1ccccc1n2
NSC Number:
88882
Properties
Computed Properties
 
Complexity:
234  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
XLogP3:
2.3  

Downstream Synthesis Route

[1]HelveticaChimicaActa,1950,vol.33,p.766,770

[1]JournaloftheSocietyofChemicalIndustry,1947,vol.66,p.11

[2]JournaloftheSocietyofChemicalIndustry,1947,vol.66,p.11

[1]JournaloftheSocietyofChemicalIndustry,1947,vol.66,p.11

[1]Wallace,JefferyM.;Söderberg,BjörnC.G.;Tamariz,Joaquín;Akhmedov,NovruzG.;Hurley,MathewT.[Tetrahedron,2008,vol.64,#41,p.9675-9684]

[1]EuropeanJournalofOrganicChemistry,2019,vol.2019,p.5424-5433

[2]OrganicandBiomolecularChemistry,2014,vol.12,p.881-886

[3]Patent:WO2015/100331,2015,A2.Locationinpatent:Paragraph00302-00305

Literature

Title: Generation of Reactive Oxygen Species Mediated by 1‑Hydroxyphenazine, a Virulence Factor of Pseudomonas aeruginosa.

Journal: Chemical research in toxicology 20150216

Title: Production, purification, and characterization of antifungal metabolite from Pseudomonas aeruginosa SD12, a new strain obtained from tannery waste polluted soil.

Journal: Journal of microbiology and biotechnology 20120501

Title: Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity.

Journal: Archives of toxicology 20120201

Title: Chromophenazines from the terrestrial Streptomyces sp. Ank 315.

Journal: Journal of natural products 20120127

Title: Metabolic profiling and biological activities of bioactive compounds produced by Pseudomonas sp. strain ICTB-745 isolated from Ladakh, India.

Journal: Journal of microbiology and biotechnology 20120101

Title: Tasco®: a product of Ascophyllum nodosum enhances immune response of Caenorhabditis elegans against Pseudomonas aeruginosa infection.

Journal: Marine drugs 20120101

Title: Quantifying the dynamics of bacterial secondary metabolites by spectral multiphoton microscopy.

Journal: ACS chemical biology 20110916

Title: Izumiphenazine D, a new phenazoquinoline N-oxide from Streptomyces sp. IFM 11204.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Bioactive pigments from marine bacteria: applications and physiological roles.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes.

Journal: Applied microbiology and biotechnology 20100501

Title: Scarless and sequential gene modification in Pseudomonas using PCR product flanked by short homology regions.

Journal: BMC microbiology 20100101

Title: Inflammatory mechanisms in the lung.

Journal: Journal of inflammation research 20090101

Title: Cell wall glycans and soluble factors determine the interactions between the hyphae of Candida albicans and Pseudomonas aeruginosa.

Journal: FEMS microbiology letters 20081001

Title: Redox reactions of phenazine antibiotics with ferric (hydr)oxides and molecular oxygen.

Journal: Environmental science & technology 20080401

Title: Widespread pyocyanin over-production among isolates of a cystic fibrosis epidemic strain.

Journal: BMC microbiology 20070101

Title: State of the art: why do the lungs of patients with cystic fibrosis become infected and why can't they clear the infection?

Journal: Respiratory research 20030101

Title: Induction of neutrophil apoptosis by the Pseudomonas aeruginosa exotoxin pyocyanin: a potential mechanism of persistent infection.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020215

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