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53-34-9,MFCD00200355
Catalog No.:AA00DE5X

53-34-9 | Fluprednisolone

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5mg
98%(HPLC)
in stock  
$154.00   $108.00
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25mg
98%(HPLC)
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$440.00   $308.00
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100mg
98%(HPLC)
in stock  
$1,035.00   $725.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DE5X
Chemical Name:
Fluprednisolone
CAS Number:
53-34-9
Molecular Formula:
C21H27FO5
Molecular Weight:
378.4345
MDL Number:
MFCD00200355
SMILES:
OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F
NSC Number:
47439
Properties
Computed Properties
 
Complexity:
760  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
1.4  

Literature

Title: Treatment of diffuse diabetic macular oedema using steroid eye drops.

Journal: Acta ophthalmologica 20121101

Title: Hypopyon uveitis following LASIK in a patient with ulcerative colitis.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20120801

Title: Efficacy and potential complications of difluprednate use for pediatric uveitis.

Journal: American journal of ophthalmology 20120501

Title: Vogt-Koyanagi-Harada syndrome in a 6-year-old Hispanic boy.

Journal: Pediatric dermatology 20120101

Title: Graft rejection after Descemet's stripping automated endothelial keratoplasty: graft survival and endothelial cell loss.

Journal: Ophthalmology 20120101

Title: Chronic anterior uveitis in common variable immunodeficiency.

Journal: Ocular immunology and inflammation 20111201

Title: Impact of isoflupredone acetate treatment on clinical signs and weight gain in weanling heifers with experimentally induced Mannheimia haemolytica bronchopneumonia.

Journal: American journal of veterinary research 20111201

Title: A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery.

Journal: American journal of ophthalmology 20111001

Title: Elevation of intraocular pressure in patients with uveitis treated with topical difluprednate.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20110501

Title: Difluprednate for inflammatory eye disorders.

Journal: Drugs of today (Barcelona, Spain : 1998) 20110501

Title: Effects of twice-daily topical difluprednate 0.05% emulsion in a child with pars planitis.

Journal: Ocular immunology and inflammation 20110201

Title: Ocular distribution of difluprednate ophthalmic emulsion 0.05% in rabbits.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110201

Title: Pharmacokinetic features of difluprednate ophthalmic emulsion in rabbits as determined by glucocorticoid receptor-binding bioassay.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20110201

Title: Intraocular pressure elevation from topical difluprednate use.

Journal: Optometry (St. Louis, Mo.) 20101201

Title: Pathology in practice. Pemphigus foliaceous.

Journal: Journal of the American Veterinary Medical Association 20101101

Title: Durezol (Difluprednate Ophthalmic Emulsion 0.05%) compared with Pred Forte 1% ophthalmic suspension in the treatment of endogenous anterior uveitis.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20101001

Title: Metabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100801

Title: Steroid eye drop treatment (difluprednate ophthalmic emulsion) is effective in reducing refractory diabetic macular edema.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100601

Title: New drugs 09, part 2.

Journal: Nursing 20090601

Title: Difluprednate ophthalmic emulsion 0.05% for postoperative inflammation and pain.

Journal: Journal of cataract and refractive surgery 20090101

Title: New drugs: Clevidipine butyrate, difluprednate, and tetrabenazine.

Journal: Journal of the American Pharmacists Association : JAPhA 20080101

Title: Effect of isoflupredone acetate with or without insulin on energy metabolism, reproduction, milk production, and health in dairy cows in early lactation.

Journal: Journal of dairy science 20070901

Title: Effects of dexamethasone and isoflupredone acetate on plasma potassium concentrations and other biochemical measurements in dairy cows in early lactation.

Journal: American journal of veterinary research 20060701

Title: Topical steroid and antibiotic combination therapy in red eye conditions.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20060401

Title: Injection site with generalized rash caused by pegylated interferon alpha 2a injection.

Journal: Dermatology (Basel, Switzerland) 20060101

Title: Formulation of an ophthalmic lipid emulsion containing an anti-inflammatory steroidal drug, difluprednate.

Journal: International journal of pharmaceutics 20050914

Title: Cutaneous reactions to imatinib mesylate treated by topical steroid.

Journal: American journal of hematology 20050301

Title: Conjunctival lymphoid hyperplasia presenting with bilateral panuveitis.

Journal: American journal of ophthalmology 20050301

Title: [Traumatic lesion of the optic nerve head by flying fish: a case report].

Journal: Klinische Monatsblatter fur Augenheilkunde 20040501

Title: Evaluation of exogenous glucocorticoid injection on preweaning growth performance of neonatal pigs under commercial conditions.

Journal: Journal of animal science 20040401

Title: Effects of two anti-inflammatory drugs on physiologic variables and milk production in cows with endotoxin-induced mastitis.

Journal: American journal of veterinary research 20040101

Title: Comparison of efficacy and tolerability of isoflupredone and dexamethasone in the treatment of horses affected with recurrent airway obstruction ('heaves').

Journal: Equine veterinary journal 20030601

Title: Pharmacodynamics of isoflupredone acetate in an endotoxin-induced mastitis model.

Journal: Journal of dairy science 20030301

Title: Analysis of an anti-inflammatory steroidal drug, difluprednate, in aqueous humor by combination of semi-micro HPLC and column switching method.

Journal: Journal of pharmaceutical and biomedical analysis 20030115

Title: Effect of chirality at C-20 of methyl 11beta,17alpha,20-trihydroxy-3-oxo-1,4-pregnadien-21-oate derivatives on antiinflammatory activity.

Journal: Steroids 20020401

Title: The identification of related substances in 9 alpha-fluoroprednisolone-21 acetate by means of high-performance liquid chromatography with diode array detector and mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 19920601

Title: [Severe hypokalemic episode induced by abuse of fluoro-prednisolone acetate administered nasally and the simultaneous oral consumption of indapamide].

Journal: La Clinica terapeutica 19850131

Title: Residue determination of 9alpha-fluoroprednisolone acetate and its metabolite 9alpha-fluoroprednisolone in bovine tissues.

Journal: Journal of agricultural and food chemistry 19740101

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Tags:53-34-9 Molecular Formula|53-34-9 MDL|53-34-9 SMILES|53-34-9 Fluprednisolone