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53016-31-2,MFCD03695603
Catalog No.:AA00DAL4

53016-31-2 | DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)

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5mg
≥95%
in stock  
$73.00   $51.00
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10mg
≥95%
in stock  
$132.00   $92.00
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25mg
≥95%
in stock  
$255.00   $178.00
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50mg
≥95%
in stock  
$472.00   $330.00
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100mg
98%
in stock  
$718.00   $503.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DAL4
Chemical Name:
DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)
CAS Number:
53016-31-2
Molecular Formula:
C21H29NO2
Molecular Weight:
327.4605
MDL Number:
MFCD03695603
SMILES:
O/N=C/1\CC[C@H]2C(=C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@]2(O)C#C)CC
Properties
Computed Properties
 
Complexity:
642  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
Undefined Bond Stereocenter Count:
1  
XLogP3:
3.6  

Literature

Title: Differences in prescription rates and odds ratios of antidepressant drugs in relation to individual hormonal contraceptives: a nationwide population-based study with age-specific analyses.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20120401

Title: Contraceptive efficacy of oral and transdermal hormones when co-administered with protease inhibitors in HIV-1-infected women: pharmacokinetic results of ACTG trial A5188.

Journal: Journal of acquired immune deficiency syndromes (1999) 20101201

Title: Effects of the contraceptive patch and the vaginal ring on bone metabolism and bone mineral density: a prospective, controlled, randomized study.

Journal: Contraception 20100301

Title: Determination of norelgestromin in rabbit plasma by LC-MS/MS and its application to the pharmacokinetic study of ORTHO EVRA.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090115

Title: Influence of taranabant, an orally active, highly selective, potent cannabinoid-1 receptor (CB1R) inverse agonist, on ethinyl estradiol and norelgestromin plasma pharmacokinetics.

Journal: Journal of clinical pharmacology 20090101

Title: Satisfaction and compliance in hormonal contraception: the result of a multicentre clinical study on women's experience with the ethinylestradiol/norelgestromin contraceptive patch in Italy.

Journal: BMC women's health 20090101

Title: Effects of oral and transdermal hormonal contraception on vascular risk markers: a randomized controlled trial.

Journal: Obstetrics and gynecology 20080201

Title: A clinical study of transdermal contraceptive patch in Thai adolescence women.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080201

Title: Effect of the ethinylestradiol/norelgestromin contraceptive patch on body composition. Results of bioelectrical impedance analysis in a population of Italian women.

Journal: Nutrition journal 20080101

Title: Oral and transdermal hormonal contraception in women after kidney transplantation.

Journal: Transplantation proceedings 20071101

Title: Pharmacokinetics and pharmacodynamics of a transdermal contraceptive patch and an oral contraceptive.

Journal: Journal of clinical pharmacology 20070401

Title: Antiandrogenic activity of norgestimate in a human androgen-dependent stable-transfected cell line.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20070401

Title: Performance of contraceptive patch compared with oral contraceptive pill in a high-risk population.

Journal: Obstetrics and gynecology 20061201

Title: A clinical study of transdermal contraceptive patch in Thai women.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20061001

Title: The Evra (ethinyl estradiol/norelgestromin) contraceptive patch: estrogen exposure concerns.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060117

Title: How should we advise patients about the contraceptive patch, given the FDA warning?

Journal: Cleveland Clinic journal of medicine 20060101

Title: New warning on birth control patch.

Journal: FDA consumer 20060101

Title: Hormonal contraception: recent advances.

Journal: The journal of family health care 20060101

Title: [Safety evaluation of a transdermal contraceptive system with an oral contraceptive].

Journal: Ginekologia polska 20051101

Title: Norelgestromin/ethinyl estradiol transdermal system.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051001

Title: Extended use of transdermal norelgestromin/ethinyl estradiol: a randomized trial.

Journal: Obstetrics and gynecology 20050601

Title: Suppression of estrogen-withdrawal headache with extended transdermal contraception.

Journal: Fertility and sterility 20050601

Title: Effect of oral versus transdermal steroidal contraceptives on androgenic markers.

Journal: American journal of obstetrics and gynecology 20050601

Title: Adolescents' experience with the combined estrogen and progestin transdermal contraceptive method Ortho Evra.

Journal: Journal of pediatric and adolescent gynecology 20050401

Title: Preference for and satisfaction of Canadian women with the transdermal contraceptive patch versus previous contraceptive method: an open-label, multicentre study.

Journal: Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20050401

Title: Effect of multiple-dose dexloxiglumide on the pharmacokinetics of oral contraceptives in healthy women.

Journal: Journal of clinical pharmacology 20050301

Title: Nondaily hormonal contraception: establishing a fit between product characteristics and patient preferences.

Journal: The Journal of family practice 20041101

Title: [Hormonal contraceptive patch].

Journal: Ugeskrift for laeger 20041004

Title: Induction of androgen receptor activity by norgestimate and norelgestromin in MDA-MB 231 breast cancer cells.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040701

Title: An evaluation of the use of the transdermal contraceptive patch in adolescents.

Journal: The Journal of adolescent health : official publication of the Society for Adolescent Medicine 20040501

Title: New Product Review (September 2003). Norelgestromin/ethinyl oestradiol transdermal contraceptive system (Evra).

Journal: The journal of family planning and reproductive health care 20040101

Title: Matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 expression is not regulated by norgestimate or norelgestromin.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040101

Title: Long-term evaluation of the use of the transdermal contraceptive patch in adolescents.

Journal: TheScientificWorldJournal 20040101

Title: [Transdermal contraception--a new beginning].

Journal: Akusherstvo i ginekologiia 20040101

Title: New contraception options.

Journal: Diabetes self-management 20040101

Title: New hormonal contraceptives: a comprehensive review of the literature.

Journal: Pharmacotherapy 20031201

Title: Evra--a patch on oral contraception?

Journal: Drug and therapeutics bulletin 20031201

Title: [Medication of the month. Evra: first contraceptive transdermal patch].

Journal: Revue medicale de Liege 20031101

Title: [A transdermal form of combined hormonal contraceptives (EVRA)].

Journal: Ceska gynekologie 20031001

Title: Ortho Evra/Evra versus oral contraceptives: follicular development and ovulation in normal cycles and after an intentional dosing error.

Journal: Fertility and sterility 20030701

Title: New drugs 2003, part II.

Journal: Nursing 20030701

Title: Transdermal delivery of sex steroids for hormone replacement therapy and contraception. A review of principles and practice.

Journal: The Journal of reproductive medicine 20030701

Title: Ortho Evra, a new contraceptive patch.

Journal: Pharmacotherapy 20030401

Title: Transdermal contraceptive patch delivering norelgestromin and ethinyl estradiol. Effects on the lipid profile.

Journal: The Journal of reproductive medicine 20030301

Title: Serum distribution of the major metabolites of norgestimate in relation to its pharmacological properties.

Journal: Contraception 20030201

Title: Norelgestromin as selective estrogen enzyme modulator in human breast cancer cell lines. Effect on sulfatase activity in comparison to medroxyprogesterone acetate.

Journal: The Journal of steroid biochemistry and molecular biology 20030201

Title: Progress in contraception: new technology.

Journal: International journal of fertility and women's medicine 20030101

Title: Women prefer Ortho Evra patch.

Journal: AWHONN lifelines 20030101

Title: Transdermal ethinylestradiol/norelgestromin: a review of its use in hormonal contraception.

Journal: Treatments in endocrinology 20030101

Title: The introduction of a transdermal hormonal contraceptive (Ortho Evra/Evra).

Journal: Fertility and sterility 20020201

Title: Pharmacokinetic overview of Ortho Evra/Evra.

Journal: Fertility and sterility 20020201

Title: Contraceptive efficacy and cycle control with the Ortho Evra/Evra transdermal system: the analysis of pooled data.

Journal: Fertility and sterility 20020201

Title: A comparative and pooled analysis of the safety and tolerability of the contraceptive patch (Ortho Evra/Evra).

Journal: Fertility and sterility 20020201

Title: Assessment of compliance with a weekly contraceptive patch (Ortho Evra/Evra) among North American women.

Journal: Fertility and sterility 20020201

Title: Integrated summary of Ortho Evra/Evra contraceptive patch adhesion in varied climates and conditions.

Journal: Fertility and sterility 20020201

Title: Pharmacokinetics of a contraceptive patch (Evra/Ortho Evra) containing norelgestromin and ethinyloestradiol at four application sites.

Journal: British journal of clinical pharmacology 20020201

Title: Ortho Evra--a contraceptive patch.

Journal: The Medical letter on drugs and therapeutics 20020121

Title: The transdermal contraceptive patch: a new approach to hormonal contraception.

Journal: International journal of fertility and women's medicine 20020101

Title: Transdermal contraception.

Journal: Seminars in reproductive medicine 20011201

Title: Pharmacokinetics of norelgestromin and ethinyl estradiol delivered by a contraceptive patch (Ortho Evra/Evra) under conditions of heat, humidity, and exercise.

Journal: Journal of clinical pharmacology 20011201

Title: Pharmacokinetics of norelgestromin and ethinyl estradiol from two consecutive contraceptive patches.

Journal: Journal of clinical pharmacology 20011101

Title: Efficacy and safety of a transdermal contraceptive system.

Journal: Obstetrics and gynecology 20011101

Title: Multiple-dose pharmacokinetics of a contraceptive patch in healthy women participants.

Journal: Contraception 20011101

Title: Norgestimate. From the laboratory to three clinical indications.

Journal: The Journal of reproductive medicine 20010701

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Tags:53016-31-2 Molecular Formula|53016-31-2 MDL|53016-31-2 SMILES|53016-31-2 DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE)