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531-44-2,MFCD02259444
Catalog No.:AA00DCA2

531-44-2 | Scopolin

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1mg
≥98%
in stock  
$89.00   $62.00
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5mg
≥98%
in stock  
$278.00   $194.00
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10mg
≥98%
in stock  
$386.00   $270.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DCA2
Chemical Name:
Scopolin
CAS Number:
531-44-2
Molecular Formula:
C16H18O9
Molecular Weight:
354.3087
MDL Number:
MFCD02259444
SMILES:
OC[C@H]1O[C@@H](Oc2cc3oc(=O)ccc3cc2OC)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Properties
 
BP:
650.2°C at 760 mmHg  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
510  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
-1.1  

Literature

Title: Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation.

Journal: Archives of pharmacal research 20120601

Title: The cyclic nucleotide cGMP is involved in plant hormone signalling and alters phosphorylation of Arabidopsis thaliana root proteins.

Journal: Journal of experimental botany 20120501

Title: Anti-inflammatory changes of gene expression by Artemisia iwayomogi in the LPS-stimulated human gingival fibroblast: microarray analysis.

Journal: Archives of pharmacal research 20120301

Title: [Coumarins from Skimmia arborescens and its anti-inflammatory effect].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120301

Title: Identification and functional characterization of cDNAs coding for hydroxybenzoate/hydroxycinnamate glucosyltransferases co-expressed with genes related to proanthocyanidin biosynthesis.

Journal: Journal of experimental botany 20120201

Title: The coumarin scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory.

Journal: Neuroscience 20111201

Title: Unique defense strategy by the endoplasmic reticulum body in plants.

Journal: Plant & cell physiology 20111201

Title: Phenolic glycosides from sugar maple (Acer saccharum) bark.

Journal: Journal of natural products 20111128

Title: Changes in scopoletin concentration in cassava chips from four varieties during storage.

Journal: Journal of the science of food and agriculture 20111001

Title: Inhibition of 5-lipoxygenase and skin inflammation by the aerial parts of Artemisia capillaris and its constituents.

Journal: Archives of pharmacal research 20110901

Title: Extraction and identification of three major aldose reductase inhibitors from Artemisia montana.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110201

Title: Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115

Title: Association of leaf micro-morphological characters with powdery mildew resistance in field-grown mulberry (Morus spp.) germplasm.

Journal: AoB PLANTS 20110101

Title: Phytochemical and biological investigations of Atriplex semibacata R .BR. growing in Egypt.

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101

Title: Cassava: an appraisal of its phytochemistry and its biotechnological prospects.

Journal: Phytochemistry 20101201

Title: [Chemical constituents from Hydrangea paniculata].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101

Title: The differential spatial distribution of secondary metabolites in Arabidopsis leaves reacting hypersensitively to Pseudomonas syringae pv. tomato is dependent on the oxidative burst.

Journal: Journal of experimental botany 20100701

Title: Constituents and secondary metabolite natural products in fresh and deteriorated cassava roots.

Journal: Phytochemistry 20100401

Title: Coumarins from the leaves of Bambusa pervariabilis McClure.

Journal: Journal of Asian natural products research 20100301

Title: Scopolin-hydrolyzing beta-glucosidases in roots of Arabidopsis.

Journal: Plant & cell physiology 20100101

Title: Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints.

Journal: International journal of molecular sciences 20100101

Title: Method development and validation for the simultaneous determination of four coumarins in Saussurea superba by capillary zone electrophoresis.

Journal: Journal of AOAC International 20100101

Title: Traditional herbal medicine in far-west Nepal: a pharmacological appraisal.

Journal: Journal of ethnobiology and ethnomedicine 20100101

Title: Diterpene esters and phenolic compounds from Sapium insigne (ROYLE) BENTH. ex HOOK. fil.

Journal: Chemical & pharmaceutical bulletin 20091101

Title: [Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901

Title: [Non-alkaloid constituents of Gelsemium elegans].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901

Title: Scopolin isolated from Erycibe obtusifolia Benth stems suppresses adjuvant-induced rat arthritis by inhibiting inflammation and angiogenesis.

Journal: International immunopharmacology 20090701

Title: Protein and metabolite analysis reveals permanent induction of stress defense and cell regeneration processes in a tobacco cell suspension culture.

Journal: International journal of molecular sciences 20090701

Title: [Effects of chemical constituents of Crossostephium chinense on insulin secretion in rat islets in vitro].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090601

Title: Novel sesquiterpene and coumarin constituents from the whole herbs of Crossostephium chinense.

Journal: Journal of Asian natural products research 20090101

Title: Investigation of biosynthetic pathways to hydroxycoumarins during post-harvest physiological deterioration in Cassava roots by using stable isotope labelling.

Journal: Chembiochem : a European journal of chemical biology 20081215

Title: Biosynthesis of scopoletin and scopolin in cassava roots during post-harvest physiological deterioration: the E-Z-isomerisation stage.

Journal: Phytochemistry 20081201

Title: A high-performance liquid chromatographic method for determination of scopolin in rat plasma: application to pharmacokinetic studies.

Journal: Biomedical chromatography : BMC 20081001

Title: Scopoletin is biosynthesized via ortho-hydroxylation of feruloyl CoA by a 2-oxoglutarate-dependent dioxygenase in Arabidopsis thaliana.

Journal: The Plant journal : for cell and molecular biology 20080901

Title: Evaluation of natural substances from Evolvulus alsinoides L. with the purpose of determining their antioxidant potency.

Journal: Journal of enzyme inhibition and medicinal chemistry 20080801

Title: On the extent and origins of genic novelty in the phylum Nematoda.

Journal: PLoS neglected tropical diseases 20080701

Title: [Studies on chemical constituents of Saussurea laniceps].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501

Title: Antifungal activity of a new phenolic compound from capitulum of a head rot-resistant sunflower genotype.

Journal: Journal of chemical ecology 20071201

Title: Regulation of arbuscular mycorrhization by apoplastic invertases: enhanced invertase activity in the leaf apoplast affects the symbiotic interaction.

Journal: The Plant journal : for cell and molecular biology 20070801

Title: Cytotoxic triterpenoid saponins from the fruits of Aesculus pavia L.

Journal: Phytochemistry 20070801

Title: A new C9 nor-isoprenoid glucoside from Rantherium suaveolens.

Journal: Natural product research 20070801

Title: Rare biscoumarins and a chlorogenic acid derivative from Erycibe obtusifolia.

Journal: Phytochemistry 20070701

Title: Structures, biogenesis, and biological activities of pyrano[4,3-c]isochromen-4-one derivatives from the Fungus Phellinus igniarius.

Journal: Journal of natural products 20070201

Title: Identification and determination of glycosides in tobacco leaves by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry.

Journal: Journal of separation science 20070201

Title: [Studies on the chemical constituents from Inula cappa (II)].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101

Title: Accumulation of coumarins in Arabidopsis thaliana.

Journal: Phytochemistry 20060201

Title: Growth at elevated CO2 concentrations leads to modified profiles of secondary metabolites in tobacco cv. SamsunNN and to increased resistance against infection with potato virus Y.

Journal: Plant, cell & environment 20060101

Title: A new bisabolane sesquiterpenoid from Euphorbia chrysocoma.

Journal: Journal of Asian natural products research 20051201

Title: Morning glory systemically accumulates scopoletin and scopolin after interaction with Fusarium oxysporum.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

Title: Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products.

Journal: Journal of medicinal chemistry 20041202

Title: Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism.

Journal: The Plant cell 20041001

Title: Ectopic expression of a UDP-glucose:phenylpropanoid glucosyltransferase leads to increased resistance of transgenic tobacco plants against infection with Potato Virus Y.

Journal: Plant & cell physiology 20040901

Title: Phenylpropanoids, phenylalanine ammonia lyase and peroxidases in elicitor-challenged cassava (Manihot esculenta) suspension cells and leaves.

Journal: Annals of botany 20040701

Title: Cytotoxic activity of five compounds isolated from Colombian plants.

Journal: Fitoterapia 20040301

Title: Agrobacterium tumefaciens AK-6b gene modulates phenolic compound metabolism in tobacco.

Journal: Phytochemistry 20040101

Title: Active components from Artemisia iwayomogi displaying ONOO(-) scavenging activity.

Journal: Phytotherapy research : PTR 20040101

Title: Phytochemical constituents from Diodia teres.

Journal: Archives of pharmacal research 20040101

Title: Over-expression of a scopoletin glucosyltransferase in Nicotiana tabacum leads to precocious lesion formation during the hypersensitive response to tobacco mosaic virus but does not affect virus resistance.

Journal: Plant molecular biology 20040101

Title: Scaphopetalone and scaphopetalumate, a lignan and a triterpene ester from Scaphopetalum thonneri.

Journal: Phytochemistry 20030201

Title: Study on the determination of polyphenols in tobacco by HPLC coupled with ESI-MS after solid-phase extraction.

Journal: Journal of chromatographic science 20030101

Title: Resistance of transgenic tobacco seedlings expressing the Agrobacterium tumefaciens C58-6b gene, to growth-inhibitory levels of cytokinin is associated with elevated IAA levels and activation of phenylpropanoid metabolism.

Journal: Plant & cell physiology 20020801

Title: Downregulation of a pathogen-responsive tobacco UDP-Glc:phenylpropanoid glucosyltransferase reduces scopoletin glucoside accumulation, enhances oxidative stress, and weakens virus resistance.

Journal: The Plant cell 20020501

Title: [Nonpolar components of the leaves of Philadelphus coronarius L].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20011101

Title: [Determination of polyphenols in tobacco by solid phase extraction and high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20011101

Title: Patterns of phenylpropanoids in non-inoculated and potato virus Y-inoculated leaves of transgenic tobacco plants expressing yeast-derived invertase.

Journal: Phytochemistry 20010301

Title: Studies on the constituents of the leaves of Morus alba L.

Journal: Chemical & pharmaceutical bulletin 20010201

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