Home Other Building Blocks 53179-09-2
53179-09-2,MFCD00210364
Catalog No.:AA00DEFX

53179-09-2 | Sisomicin sulfate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
in stock  
$59.00   $42.00
- +
250mg
>98.0%(HPLC)
in stock  
$68.00   $48.00
- +
1g
>98.0%(HPLC)
in stock  
$165.00   $116.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DEFX
Chemical Name:
Sisomicin sulfate
CAS Number:
53179-09-2
Molecular Formula:
C19H37N5O7
Molecular Weight:
447.5264
MDL Number:
MFCD00210364
SMILES:
NCC1=CCC([C@H](O1)O[C@@H]1[C@H](N)C[C@H](C(C1O)O[C@H]1OC[C@]([C@@H](C1O)NC)(C)O)N)N C19H37N5O7
Properties
Computed Properties
 
Complexity:
724  
Covalently-Bonded Unit Count:
7  
Defined Atom Stereocenter Count:
22  
Heavy Atom Count:
87  
Hydrogen Bond Acceptor Count:
44  
Hydrogen Bond Donor Count:
26  
Rotatable Bond Count:
12  

Literature

Title: Activity of plazomicin (ACHN-490) against MDR clinical isolates of Klebsiella pneumoniae, Escherichia coli, and Enterobacter spp. from Athens, Greece.

Journal: Journal of chemotherapy (Florence, Italy) 20120801

Title: A high pH based reversed-phase high performance liquid chromatographic method for the analysis of aminoglycoside plazomicin and its impurities.

Journal: Journal of pharmaceutical and biomedical analysis 20120701

Title: Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin.

Journal: Expert review of anti-infective therapy 20120401

Title: EPR studies of free radicals decay and survival in gamma irradiated aminoglycoside antibiotics: sisomicin, tobramycin and paromomycin.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120214

Title: Hybrid aminoglycoside antibiotics via Tsuji palladium-catalyzed allylic deoxygenation.

Journal: Organic letters 20111216

Title: Activity of ACHN-490 against meticillin-resistant Staphylococcus aureus (MRSA) isolates from patients in US hospitals.

Journal: International journal of antimicrobial agents 20111001

Title: Antimicrobial activity of a novel aminoglycoside, ACHN-490, against Acinetobacter baumannii and Pseudomonas aeruginosa from New York City.

Journal: The Journal of antimicrobial chemotherapy 20110201

Title: Activity of aminoglycosides, including ACHN-490, against carbapenem-resistant Enterobacteriaceae isolates.

Journal: The Journal of antimicrobial chemotherapy 20110101

Title: Activity of a novel aminoglycoside, ACHN-490, against clinical isolates of Escherichia coli and Klebsiella pneumoniae from New York City.

Journal: The Journal of antimicrobial chemotherapy 20101001

Title: Combating evolution with intelligent design: the neoglycoside ACHN-490.

Journal: Current opinion in microbiology 20101001

Title: Biomimetic synthesis and structural refinement of the macrocyclic dimer aminoglycoside 66-40C--the remarkably selective self-condensation of a putative aldehyde intermediate in the submerged culture medium producing sisomicin.

Journal: Chemical communications (Cambridge, England) 20100328

Title: Immunoassays for the rapid detection of gentamicin and micronomicin in swine muscle.

Journal: Journal of AOAC International 20100101

Title: Development of a non-derivatization high-performance liquid chromatography method with resonance Rayleigh scattering detection for the detection of sisomicin in rat serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091201

Title: Molecular cloning and sequence analysis of the sisomicin biosynthetic gene cluster from Micromonospora inyoensis.

Journal: Biotechnology letters 20090301

Title: Characterization and identification of a novel marine Streptomyces sp. produced antibacterial substance.

Journal: Marine biotechnology (New York, N.Y.) 20090101

Title: Characterization of impurities in sisomicin and netilmicin by liquid chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20081101

Title: Improved liquid chromatographic method with pulsed electrochemical detection for the analysis of gentamicin.

Journal: Journal of chromatography. A 20080502

Title: Micellar electrokinetic chromatography of aminoglycosides.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Evaluation of combined deactivators-supplemented agar medium (CDSAM) for recovery of dermatophytes from patients with tinea pedis.

Journal: Medical mycology 20070601

Title: [Study on cloning of sisomicin-resistant gene (sisR) from Micromonospora inyoensis].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20050101

Title: ATP, histidine or magnesium ions can protect DNA against sisomicin-induced damage, following stray Cu(II) binding.

Journal: Archives of biochemistry and biophysics 20041101

Title: Acid-base versus structural properties of an aminoglycoside antibiotic--sisomicin: NMR and potentiometric approach.

Journal: Bioorganic & medicinal chemistry 20040801

Title: Effectiveness of short-term antibiotic prophylaxis on postoperative recovery course after pulmonary lobectomies.

Journal: Journal of the Chinese Medical Association : JCMA 20040601

Title: A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics.

Journal: Electrophoresis 20030901

Title: [Comparative ototoxicity of aminoglycoside antibiotics in a guinea pig model (author's transl)].

Journal: La Nouvelle presse medicale 19781129

Title: Hypocalcemia with hypoparathyroidism and renal tubular dysfunction associated with aminoglycoside therapy.

Journal: Cancer 19770401

Title: Crowe CC, et al. Sisomicin: evaluation in vitro and comparison with gentamicin and tobramycin. Antimicrob Agents Chemother. 1973 Jan;3(1):24-8.

Title: P Noone, et al. Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use. Drugs. 1984 Jun;27(6):548-78.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 53179-09-2
Tags:53179-09-2 Molecular Formula|53179-09-2 MDL|53179-09-2 SMILES|53179-09-2 Sisomicin sulfate