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53524-81-5,MFCD03109883
Catalog No.:AA00DD1F

53524-81-5 | 3-Methyl-1-benzofuran-2-carbohydrazide

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1g
95%
in stock  
$245.00   $172.00
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5g
95%
in stock  
$978.00   $685.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DD1F
Chemical Name:
3-Methyl-1-benzofuran-2-carbohydrazide
CAS Number:
53524-81-5
Molecular Formula:
C10H10N2O2
Molecular Weight:
190.1986
MDL Number:
MFCD03109883
SMILES:
NNC(=O)c1oc2c(c1C)cccc2
Properties
Computed Properties
 
Complexity:
232  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.6  

Downstream Synthesis Route

[1]Gao,Yuan;He,Xingrui;Hui,Zi;Shen,Guodong;Wang,Shuo;Xie,Tian;Ye,Xiang-Yang[Bioorganicandmedicinalchemistryletters,2020,vol.30,#10]

[2]Abdel-Aziz,HatemA.;Al-Sanea,MohammadM.;Al-Warhi,Tarfah;Aljaeed,Nada;Alotaibi,OhoudJ.;Eldehna,WagdyM.;Elsayed,ZainabM.;Nocentini,Alessio;Supuran,ClaudiuT.[ACSMedicinalChemistryLetters,2020,vol.11,#5,p.1022-1027]

[3]Al-Sanea,MohammadM.;Al-Ansary,GhadaH.;Elsayed,ZainabM.;Maklad,RaedM.;Elkaeed,EslamB.;Abdelgawad,MohamedA.;Bukhari,SyedNasirAbbas;Abdel-Aziz,MarwaM.;Suliman,Howayda;Eldehna,WagdyM.[JournalofEnzymeInhibitionandMedicinalChemistry,2021,vol.36,#1,p.987-999]

[4]Thorat,BapuR.;Nazirkar,Bhusan;Thorat,VaishaliB.;More,Kishor;Jagtap,Ravindra;Yamgar,Ramesh[AsianJournalofChemistry,2016,vol.28,#11,p.2346-2352]

[5]Shaldam,Moataz;Eldehna,WagdyM.;Nocentini,Alessio;Elsayed,ZainabM.;Ibrahim,TamerM.;Salem,Rofaida;El-Domany,RamadanA.;Capasso,Clemente;Abdel-Aziz,HatemA.;Supuran,ClaudiuT.[EuropeanJournalofMedicinalChemistry,2021,vol.216]

[6]Eldehna,WagdyM.;Salem,Rofaida;Elsayed,ZainabM.;Al-Warhi,Tarfah;Knany,HamadaR.;Ayyad,RezkR.;Traiki,ThamerBin;Abdulla,Maha-Hamadien;Ahmad,Rehan;Abdel-Aziz,HatemA.;El-Haggar,Radwan[JournalofEnzymeInhibitionandMedicinalChemistry,2021,vol.36,#1,p.1424-1435]

Literature

Title: 3-Methyl-1-benzofuran-2-carbohydrazide.

Journal: Acta crystallographica. Section E, Structure reports online 20120401

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Convenient synthesis and antimicrobial evaluation of some novel 2-substituted-3-methylbenzofuran derivatives.

Journal: European journal of medicinal chemistry 20090901

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