Home Pyridines 536-33-4
536-33-4,MFCD00057361
Catalog No.:AA00I9HG

536-33-4 | 4-Pyridinecarbothioamide, 2-ethyl-

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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00I9HG
Chemical Name:
4-Pyridinecarbothioamide, 2-ethyl-
CAS Number:
536-33-4
Molecular Formula:
C8H10N2S
Molecular Weight:
166.2434
MDL Number:
MFCD00057361
SMILES:
CCc1nccc(c1)C(=S)N
Properties
Properties
 
BP:
296.6°C at 760 mmHg  
Form:
Solid  
MP:
164 °C  
Refractive Index:
1.5500 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
147  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.1  

Literature

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Journal: Science (New York, N.Y.) 20170317

Title: Baeyer-Villiger Monooxygenases EthA and MymA Are Required for Activation of Replicating and Non-replicating Mycobacterium tuberculosis Inhibitors.

Journal: Cell chemical biology 20160623

Title: Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells.

Journal: Toxicology and applied pharmacology 20160201

Title: Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis.

Journal: Microbial cell factories 20150101

Title: Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.

Journal: Toxicology 20141003

Title: Metabolism of the antituberculosis drug ethionamide.

Journal: Current drug metabolism 20130101

Title: Identification of a novel Baeyer-Villiger monooxygenase from Acinetobacter radioresistens: close relationship to the Mycobacterium tuberculosis prodrug activator EtaA.

Journal: Microbial biotechnology 20121101

Title: Studies on catalytic enantioselective total synthesis of caprazamycin B: construction of the western zone.

Journal: The Journal of organic chemistry 20121019

Title: Evaluation of BACTEC MGIT 960 system for the second-line drugs susceptibility testing of Mycobacterium tuberculosis in China.

Journal: Journal of microbiological methods 20121001

Title: Adjuvant strategies for potentiation of antibiotics to overcome antimicrobial resistance.

Journal: Current opinion in pharmacology 20121001

Title: Predictors of sputum culture conversion among patients treated for multidrug-resistant tuberculosis.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20121001

Title: Synthesis of Fischer type-carbene complexes containing a coordinated thioimidate structural motif.

Journal: Dalton transactions (Cambridge, England : 2003) 20120921

Title: Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120901

Title: Predictors of poor outcomes among patients treated for multidrug-resistant tuberculosis at DOTS-plus projects.

Journal: Tuberculosis (Edinburgh, Scotland) 20120901

Title: Strategies for potentiation of ethionamide and folate antagonists against Mycobacterium tuberculosis.

Journal: Expert review of anti-infective therapy 20120901

Title: Old drugs, new purpose: retooling existing drugs for optimized treatment of resistant tuberculosis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120815

Title: 3-Acetyl-1-(2,5-dimethyl-phen-yl)thio-urea.

Journal: Acta crystallographica. Section E, Structure reports online 20120801

Title: Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients.

Journal: PLoS medicine 20120801

Title: Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.

Journal: Journal of medicinal chemistry 20120726

Title: Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1).

Journal: Bioorganic & medicinal chemistry 20120715

Title: Impact of drug resistance on clinical outcome in children with tuberculous meningitis.

Journal: The Pediatric infectious disease journal 20120701

Title: Vibrational spectroscopic investigation on the structure of 2-ethylpyridine-4-carbothioamide.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120701

Title: Native chemical ligation of thioamide-containing peptides: development and application to the synthesis of labeled α-synuclein for misfolding studies.

Journal: Journal of the American Chemical Society 20120606

Title: New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601

Title: Chalcogenopyrylium compounds as modulators of the ATP-binding cassette transporters P-glycoprotein (P-gp/ABCB1) and multidrug resistance protein 1 (MRP1/ABCC1).

Journal: Journal of medicinal chemistry 20120524

Title: Amide analogues of CD1d agonists modulate iNKT-cell-mediated cytokine production.

Journal: ACS chemical biology 20120518

Title: Concise enantioselective synthesis of duloxetine via direct catalytic asymmetric aldol reaction of thioamide.

Journal: The Journal of organic chemistry 20120504

Title: Bis{4-phenyl-1-[1-(pyridin-2-yl-κN)ethyl-idene]thio-semicarbazidato-κ(2)N(1),S}cadmium.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Di-μ-bromido-bis-({2-[(4,6-dimethyl-pyrimidin-2-yl)disulfan-yl]-4,6-dimethyl-pyrimidine-κ(2)N(1),S(2)}copper(I)).

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Consistency of standard laboratory strain Mycobacterium tuberculosis H 37 Rv with ethionamide susceptibility testing.

Journal: The Indian journal of medical research 20120501

Title: Minimalist probes for studying protein dynamics: thioamide quenching of selectively excitable fluorescent amino acids.

Journal: Journal of the American Chemical Society 20120411

Title: Anti-mycobacterial activities of some cationic and anionic calix[4]arene derivatives.

Journal: Bioorganic & medicinal chemistry 20120315

Title: Antistaphylococcal activity of novel salicylanilide derivatives.

Journal: Current drug discovery technologies 20120301

Title: 3,3'-Dibenzoyl-1,1'-dibenzyl-1,1'-(ethane-1,2-di-yl)-dithio-urea.

Journal: Acta crystallographica. Section E, Structure reports online 20120301

Title: Reduction of misleading ('false') positive results in mammalian cell genotoxicity assays. I. Choice of cell type.

Journal: Mutation research 20120218

Title: Combined theoretical and experimental study on high diastereoselective chirality transfer based on [2.2]paracyclophane derivative chiral reagent.

Journal: The Journal of organic chemistry 20120217

Title: Fluorescence signaling of Zr4+ by hydrogen peroxide assisted selective desulfurization of thioamide.

Journal: Inorganic chemistry 20120206

Title: The effect of anti-tubercular drug, ethionamide on the secondary structure of serum albumins: a biophysical study.

Journal: Journal of pharmaceutical and biomedical analysis 20120205

Title: Thioamide quenching of intrinsic protein fluorescence.

Journal: Chemical communications (Cambridge, England) 20120201

Title: The good, the bad and the twisted: a survey of ligand geometry in protein crystal structures.

Journal: Journal of computer-aided molecular design 20120201

Title: Total synthesis of [Ψ[C(═S)NH]Tpg4]vancomycin aglycon, [Ψ[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

Journal: Journal of the American Chemical Society 20120118

Title: Molecular thioamide ↔ iminothiolate switches for sulfur mustards.

Journal: Inorganic chemistry 20120116

Title: Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors.

Journal: Journal of medicinal chemistry 20120112

Title: Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors.

Journal: ChemMedChem 20120102

Title: Tuberculosis in pregnancy: a review.

Journal: Journal of pregnancy 20120101

Title: The TDR Tuberculosis Strain Bank: a resource for basic science, tool development and diagnostic services.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120101

Title: Ethionamide-induced hypothyroidism.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120101

Title: Identifying co-targets to fight drug resistance based on a random walk model.

Journal: BMC systems biology 20120101

Title: Multistate outbreak of MDR TB identified by genotype cluster investigation.

Journal: Emerging infectious diseases 20120101

Title: High prevalence of multidrug-resistant tuberculosis, Swaziland, 2009-2010.

Journal: Emerging infectious diseases 20120101

Title: Mycobacterium riyadhense pulmonary infection, France and Bahrain.

Journal: Emerging infectious diseases 20120101

Title: Strategies for treating latent multiple-drug resistant tuberculosis: a decision analysis.

Journal: PloS one 20120101

Title: Ethics, human rights and programmatic management of drug-resistant tuberculosis.

Journal: Lung India : official organ of Indian Chest Society 20120101

Title: Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region.

Journal: PloS one 20120101

Title: Use of a molecular diagnostic test in AFB smear positive tuberculosis suspects greatly reduces time to detection of multidrug resistant tuberculosis.

Journal: PloS one 20120101

Title: Survival from XDR-TB is associated with modifiable clinical characteristics in rural South Africa.

Journal: PloS one 20120101

Title: TSH-CHECK-1 test: diagnostic accuracy and potential application to initiating treatment for hypothyroidism in patients on anti-tuberculosis drugs.

Journal: PloS one 20120101

Title: Efficacy of directly observed treatment short-course intermittent regimen in spinal tuberculosis.

Journal: Indian journal of orthopaedics 20120101

Title: Tuberculosis spine: Therapeutically refractory disease.

Journal: Indian journal of orthopaedics 20120101

Title: Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.

Journal: PloS one 20120101

Title: A home-based approach to managing multi-drug resistant tuberculosis in Uganda: a case report.

Journal: AIDS research and therapy 20120101

Title: The cost-effectiveness of tuberculosis preventive therapy for HIV-infected individuals in southern India: a trial-based analysis.

Journal: PloS one 20120101

Title: MycoRRdb: a database of computationally identified regulatory regions within intergenic sequences in mycobacterial genomes.

Journal: PloS one 20120101

Title: Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.

Journal: BMJ case reports 20120101

Title: Failure to recognize nontuberculous mycobacteria leads to misdiagnosis of chronic pulmonary tuberculosis.

Journal: PloS one 20120101

Title: Multidrug and extensively drug-resistant tuberculosis management: Evidences and controversies.

Journal: Lung India : official organ of Indian Chest Society 20120101

Title: Pharmacotherapy for multidrug resistant tuberculosis.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Ethionamide-induced gynecomastia.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Assessing the risk of birth defects associated with exposure to fixed-dose combined antituberculous agents during pregnancy in rats.

Journal: TheScientificWorldJournal 20120101

Title: Outcomes of comprehensive care for children empirically treated for multidrug-resistant tuberculosis in a setting of high HIV prevalence.

Journal: PloS one 20120101

Title: Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme.

Journal: Open biology 20120101

Title: Impact of isoniazid resistance-conferring mutations on the clinical presentation of isoniazid monoresistant tuberculosis.

Journal: PloS one 20120101

Title: The impact and cost of scaling up GeneXpert MTB/RIF in South Africa.

Journal: PloS one 20120101

Title: [Investigation of remaxol efficacy in complex therapy of experimental generalized tuberculosis on mice].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20120101

Title: Partial thioamide scan on the lipopeptaibiotic trichogin GA IV. Effects on folding and bioactivity.

Journal: Beilstein journal of organic chemistry 20120101

Title: Gynecomastia caused by ethionamide.

Journal: Indian journal of pharmacology 20120101

Title: Methanolysis of thioamide promoted by a simple palladacycle is accelerated by 10(8) over the methoxide-catalyzed reaction.

Journal: Journal of the American Chemical Society 20111221

Title: Further insight into the coordination of 2,5-dicarbothioamidopyrroles: the case of Cu and Co complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20111207

Title: Comparative analysis of mycobacterial NADH pyrophosphatase isoforms reveals a novel mechanism for isoniazid and ethionamide inactivation.

Journal: Molecular microbiology 20111201

Title: Redox homeostasis in mycobacteria: the key to tuberculosis control?

Journal: Expert reviews in molecular medicine 20111201

Title: Humans as source of Mycobacterium tuberculosis infection in cattle, Spain.

Journal: Emerging infectious diseases 20111201

Title: Nanoparticle delivery of anti-tuberculosis chemotherapy as a potential mediator against drug-resistant tuberculosis.

Journal: The Yale journal of biology and medicine 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: (1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimeth-oxy-1-phenyl-1,2,3,4-tetra-hydro-isoquinoline-3-carbothio-amide.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: Diagnosis & treatment of tuberculosis in HIV co-infected patients.

Journal: The Indian journal of medical research 20111201

Title: [Analytical profile of 1-[3-(3-propoxyphenylcarbamoyloxy)-2-hydroxypropyl]-4-(3-trifluoromethylphenyl)piperazinium chloride].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20111201

Title: Fetal and neonatal goiter in cynomolgus monkeys following administration of the antithyroid drug thiamazole at high doses to dams during pregnancy.

Journal: Journal of toxicologic pathology 20111201

Title: Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs.

Journal: Chemistry and physics of lipids 20111101

Title: Penetration of anti-infective agents into pulmonary epithelial lining fluid: focus on antifungal, antitubercular and miscellaneous anti-infective agents.

Journal: Clinical pharmacokinetics 20111101

Title: Mycobacterium indicus pranii as stand-alone or adjunct immunotherapeutic in treatment of experimental animal tuberculosis.

Journal: The Indian journal of medical research 20111101

Title: Direct catalytic asymmetric intramolecular conjugate addition of thioamide to α,β-unsaturated esters.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20111017

Title: Estimation of σ- and π-donor properties of heterocyclic thioamides by spectroscopic and magnetic resonance methods.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015

Title: Fluoroquinolone-resistant tuberculosis at a medical centre in Taiwan, 2005-10.

Journal: The Journal of antimicrobial chemotherapy 20111001

Title: Deprotonation/protonation of coordinated secondary thioamide units of pincer ruthenium complexes: modulation of voltammetric and spectroscopic characterization of the pincer complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20110921

Title: Synthesis of 4-methylene-4H-benzo[d][1,3]thiazines via a tandem reaction of 1-(2-alkynylphenyl)ketoximes with Lawesson's reagent.

Journal: Chemical communications (Cambridge, England) 20110914

Title: Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of ethionamide and ethionamide sulfoxide in human plasma: application to a human pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20110901

Title: WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update.

Journal: The European respiratory journal 20110901

Title: Abnormal thyroid function tests in children on ethionamide treatment.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20110901

Title: Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.

Journal: PLoS pathogens 20110901

Title: Direct Fmoc-chemistry-based solid-phase synthesis of peptidyl thioesters.

Journal: The Journal of organic chemistry 20110819

Title: The progress made in determining the Mycobacterium tuberculosis structural proteome.

Journal: Proteomics 20110801

Title: 3-(3-Meth-oxy-benzo-yl)-1,1-diphenyl-thio-urea.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: Cyclic nucleotide-gated channel block by hydrolysis-resistant tetracaine derivatives.

Journal: Journal of medicinal chemistry 20110714

Title: A stable aminothioketyl radical in the gas phase.

Journal: Journal of the American Chemical Society 20110706

Title: Cooperative activation of alkyne and thioamide functionalities; direct catalytic asymmetric conjugate addition of terminal alkynes to α,β-unsaturated thioamides.

Journal: Chemistry, an Asian journal 20110704

Title: Antimycobacterial activity of ferutinin alone and in combination with antitubercular drugs against a rapidly growing surrogate of Mycobacterium tuberculosis.

Journal: Natural product research 20110701

Title: Mechanisms of drug resistance in Mycobacterium tuberculosis and current status of rapid molecular diagnostic testing.

Journal: Acta tropica 20110701

Title: The regulation of sulfur metabolism in Mycobacterium tuberculosis.

Journal: PLoS pathogens 20110701

Title: 1,1-Dibenzyl-3-(3-chloro-benzo-yl)thio-urea.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Bioactivation of antituberculosis thioamide and thiourea prodrugs by bacterial and mammalian flavin monooxygenases.

Journal: Chemico-biological interactions 20110630

Title: The binding of triclosan to SmeT, the repressor of the multidrug efflux pump SmeDEF, induces antibiotic resistance in Stenotrophomonas maltophilia.

Journal: PLoS pathogens 20110601

Title: Multiple introductions of multidrug-resistant tuberculosis into households, Lima, Peru.

Journal: Emerging infectious diseases 20110601

Title: Therapy of hyperthyroidism in pregnancy and breastfeeding.

Journal: Obstetrical & gynecological survey 20110601

Title: Backbone modification of β-hairpin-forming tetrapeptides in asymmetric acyl transfer reactions.

Journal: The Journal of organic chemistry 20110506

Title: New and improved diagnostics for detection of drug-resistant pulmonary tuberculosis.

Journal: Current opinion in pulmonary medicine 20110501

Title: Outcome of standardized treatment for patients with MDR-TB from Tamil Nadu, India.

Journal: The Indian journal of medical research 20110501

Title: Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors.

Journal: Journal of medicinal chemistry 20110428

Title: From cationic to anionic helicenes: new reactivity through umpolung.

Journal: The Journal of organic chemistry 20110415

Title: A new DNA gyrase inhibitor subclass of the cyclothialidine family based on a bicyclic dilactam-lactone scaffold. Synthesis and antibacterial properties.

Journal: Journal of medicinal chemistry 20110414

Title: Direct catalytic enantio- and diastereoselective aldol reaction of thioamides.

Journal: Journal of the American Chemical Society 20110413

Title: Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase.

Journal: Glycobiology 20110401

Title: Wild-type distributions of seven oral second-line drugs against Mycobacterium tuberculosis.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20110401

Title: Resistance patterns of multidrug-resistant tuberculosis in Western Province, Papua New Guinea.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20110401

Title: (Benzene-carbothio-amide-κS)-penta-carbonyl-tungsten(0).

Journal: Acta crystallographica. Section E, Structure reports online 20110401

Title: Enantioselective synthesis of a GPR40 agonist AMG 837 via catalytic asymmetric conjugate addition of terminal alkyne to α,β-unsaturated thioamide.

Journal: Organic letters 20110304

Title: inhA promoter mutations: a gateway to extensively drug-resistant tuberculosis in South Africa?

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20110301

Title: Increasing drug resistance in extensively drug-resistant tuberculosis, South Africa.

Journal: Emerging infectious diseases 20110301

Title: Molecular epidemiology of Mycobacterium tuberculosis, Buenos Aires, Argentina.

Journal: Emerging infectious diseases 20110301

Title: Depressogenic effects of medications: a review.

Journal: Dialogues in clinical neuroscience 20110301

Title: Fluorescent signaling of oxone by desulfurization of thioamide.

Journal: Organic letters 20110204

Title: Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives.

Journal: Bioorganic & medicinal chemistry letters 20110201

Title: Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check.

Journal: The EMBO journal 20110105

Title: Pharmacokinetics and tissue distribution studies of orally administered nanoparticles encapsulated ethionamide used as potential drug delivery system in management of multi-drug resistant tuberculosis.

Journal: Drug delivery 20110101

Title: In vitro simulation of the chemical scenario of the action of an anti-thyroid drug: charge transfer interaction of thiazolidine-2-thione with iodine.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110101

Title: Antimicrobial Susceptibility Testing of Mycobacterium bovis Isolates from Michigan White-Tailed Deer during the 2009 Hunting Season.

Journal: Veterinary medicine international 20110101

Title: Treatment of disseminated mycobacterial infection with high-dose IFN-γ in a patient with IL-12Rβ1 deficiency.

Journal: Clinical & developmental immunology 20110101

Title: Activities of rifampin, Rifapentine and clarithromycin alone and in combination against mycobacterium ulcerans disease in mice.

Journal: PLoS neglected tropical diseases 20110101

Title: Culture conversion among HIV co-infected multidrug-resistant tuberculosis patients in Tugela Ferry, South Africa.

Journal: PloS one 20110101

Title: High prevalence of childhood multi-drug resistant tuberculosis in Johannesburg, South Africa: a cross sectional study.

Journal: BMC infectious diseases 20110101

Title: Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized controlled trial.

Journal: Trials 20110101

Title: Genomic stability over 9 years of an isoniazid resistant Mycobacterium tuberculosis outbreak strain in Sweden.

Journal: PloS one 20110101

Title: Antiretroviral therapy outcomes in HIV-infected children after adjusting protease inhibitor dosing during tuberculosis treatment.

Journal: PloS one 20110101

Title: Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis.

Journal: PloS one 20110101

Title: Disruption of cell wall fatty acid biosynthesis in Mycobacterium tuberculosis using a graph theoretic approach.

Journal: Theoretical biology & medical modelling 20110101

Title: Characterization of n-Hexane sub-fraction of Bridelia micrantha (Berth) and its antimycobacterium activity.

Journal: BMC complementary and alternative medicine 20110101

Title: HIV-Associated Tuberculosis in the Newborn and Young Infant.

Journal: International journal of pediatrics 20110101

Title: Crystal structures of the transcriptional repressor RolR reveals a novel recognition mechanism between inducer and regulator.

Journal: PloS one 20110101

Title: Enzyme Mechanism and Slow-Onset Inhibition of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase by an Inorganic Complex.

Journal: Enzyme research 20110101

Title: Lack of the delta subunit of RNA polymerase increases virulence related traits of Streptococcus mutans.

Journal: PloS one 20110101

Title: Presentation and outcome of tuberculous meningitis in a high HIV prevalence setting.

Journal: PloS one 20110101

Title: New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis.

Journal: PloS one 20110101

Title: Isoniazid-induced alopecia.

Journal: Lung India : official organ of Indian Chest Society 20110101

Title: Dynamics of antibiotic resistant Mycobacterium tuberculosis during long-term infection and antibiotic treatment.

Journal: PloS one 20110101

Title: Ethionamide-induced pellagroid dermatitis resembling lichen simplex chronicus: a report of two cases.

Journal: Indian journal of dermatology, venereology and leprology 20110101

Title: Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex for first and second line drugs by broth dilution in a microtiter plate format.

Journal: Journal of visualized experiments : JoVE 20110101

Title: DedA protein relates to action-mechanism of halicyclamine A, a marine spongean macrocyclic alkaloid, as an anti-dormant mycobacterial substance.

Journal: Marine drugs 20110101

Title: Study of Genetic Evolution in Mycobacterium tuberculosis Isolates from Patients with Active Pulmonary Tuberculosis in the Iran and Belarus.

Journal: The open microbiology journal 20110101

Title: Outcomes of multi-drug resistant tuberculosis (MDR-TB) among a cohort of South African patients with high HIV prevalence.

Journal: PloS one 20110101

Title: Tuberculosis in Sudan: a study of Mycobacterium tuberculosis strain genotype and susceptibility to anti-tuberculosis drugs.

Journal: BMC infectious diseases 20110101

Title: Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase.

Journal: PloS one 20110101

Title: Retreatment of tuberculosis patients in the city of Porto Alegre, Brazil: outcomes.

Journal: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 20110101

Title: Treatment of tuberculosis in a region with high drug resistance: outcomes, drug resistance amplification and re-infection.

Journal: PloS one 20110101

Title: Tuberculosis chemotherapy in the 21 century: Back to the basics.

Journal: Lung India : official organ of Indian Chest Society 20110101

Title: Insights from the molecular docking of withanolide derivatives to the target protein PknG from Mycobacterium tuberculosis.

Journal: Bioinformation 20110101

Title: Clonal population of Mycobacterium tuberculosis strains reside within multiple lung cavities.

Journal: PloS one 20110101

Title: Synthesis characterization and biological activity study of new schiff and mannich bases and some metal complexes derived from isatin and dithiooxamide.

Journal: Bioinorganic chemistry and applications 20110101

Title: Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y.

Journal: Chemistry Central journal 20110101

Title: In vitro physicochemical characterization and short term in vivo tolerability study of ethionamide loaded PLGA nanoparticles: potentially effective agent for multidrug resistant tuberculosis.

Journal: Journal of microencapsulation 20110101

Title: Analysis of thyroid function tests in patients of multidrug resistance tuberculosis undergoing treatment.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: Survival of drug resistant tuberculosis patients in Lithuania: retrospective national cohort study.

Journal: BMJ open 20110101

Title: Ambulatory multi-drug resistant tuberculosis treatment outcomes in a cohort of HIV-infected patients in a slum setting in Mumbai, India.

Journal: PloS one 20110101

Title: Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis.

Journal: BMC structural biology 20110101

Title: Oncolytic activities of host defense peptides.

Journal: International journal of molecular sciences 20110101

Title: The Mycobacterium tuberculosis FAS-II dehydratases and methyltransferases define the specificity of the mycolic acid elongation complexes.

Journal: PloS one 20110101

Title: Aetiology, clinical presentation, and outcome of meningitis in patients coinfected with human immunodeficiency virus and tuberculosis.

Journal: AIDS research and treatment 20110101

Title: Pattern of ethionamide susceptibility and its association with isoniazid resistance among previously treated tuberculosis patients from India.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20110101

Title: Drug-resistant tuberculosis: emerging treatment options.

Journal: Clinical pharmacology : advances and applications 20110101

Title: FReDoWS: a method to automate molecular docking simulations with explicit receptor flexibility and snapshots selection.

Journal: BMC genomics 20110101

Title: Effect of the explicit flexibility of the InhA enzyme from Mycobacterium tuberculosis in molecular docking simulations.

Journal: BMC genomics 20110101

Title: Tuberculous meningitis: diagnosis and treatment overview.

Journal: Tuberculosis research and treatment 20110101

Title: Usefulness of resistant gene markers for predicting treatment outcome on second-line anti-tuberculosis drugs.

Journal: Journal of applied microbiology 20101201

Title: Novel technologies: A weapon against tuberculosis.

Journal: Indian journal of pharmacology 20101201

Title: Structural and electronic properties of luminescent copper(I) halide complexes of bis[2-(diphenylphosphano)phenyl] ether (DPEphos). Crystal structure of [CuCl(DPEphos)(dmpymtH].

Journal: Dalton transactions (Cambridge, England : 2003) 20101114

Title: The chemotherapy of tuberculous meningitis in children and adults.

Journal: Tuberculosis (Edinburgh, Scotland) 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Evaluation of nitrate reductase assay for rapid detection of resistance to second-line drugs in Mycobacterium tuberculosis in a tertiary care hospital.

Journal: Diagnostic microbiology and infectious disease 20101101

Title: The Mycobacterium tuberculosis drugome and its polypharmacological implications.

Journal: PLoS computational biology 20101101

Title: Chlorido(η-cyclo-octa-1,5-diene)(N,N'-diethyl-thio-urea-κS)rhodium(I).

Journal: Acta crystallographica. Section E, Structure reports online 20101101

Title: Thioamides as fluorescence quenching probes: minimalist chromophores to monitor protein dynamics.

Journal: Journal of the American Chemical Society 20101027

Title: Synthesis of benzofuran, benzothiophene, and benzothiazole-based thioamides and their evaluation as K(ATP) channel openers.

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Title: A novel analog of antimicrobial peptide Polybia-MPI, with thioamide bond substitution, exhibits increased therapeutic efficacy against cancer and diminished toxicity in mice.

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Title: Phenotypic and genotypic analysis of multidrug-resistant tuberculosis in Ethiopia.

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Title: The first square-planar copper(II) 1:2 complex with differently coordinated 2-hydroxybenzaldehyde 4-allylthiosemicarbazone ligands.

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Title: Cerebrospinal fluid concentrations of antituberculosis agents in adults and children.

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Title: Extensively drug-resistant tuberculosis, Pakistan.

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Title: Evaluation of MGIT 960 and the colorimetric-based method for tuberculosis drug susceptibility testing.

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Title: Refinement of the pharmacophore of 3,4-dihydroquinazoline-2(1H)-thiones for their anti-melanogenesis activity.

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Title: Direct catalytic asymmetric conjugate addition of terminal alkynes to alpha,beta-unsaturated thioamides.

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Title: Capreomycin-induced optic neuritis in a case of multidrug resistant pulmonary tuberculosis.

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Title: Synthesis and reaction of monomeric germanium(II) and lead(II) dimethylamide and the synthesis of germanium(II) hydrazide by cleavage of one N-H bond of hydrazine.

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Title: Desymmetrization of meso-1,2-diols via the dynamic kinetic resolution of its monodichloroacetates.

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Title: Penta-carbon-yl(imidazolidine-2-thione-κS)tungsten(0).

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Title: Extensively drug-resistant tuberculosis, Burkina Faso.

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Title: Protective effect of Brewer's yeast on methimazole-induced-adrenal atrophy (a stereological study).

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Title: Initial response to protease-inhibitor-based antiretroviral therapy among children less than 2 years of age in South Africa: effect of cotreatment for tuberculosis.

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Title: Genotypic analysis of genes associated with isoniazid and ethionamide resistance in MDR-TB isolates from Thailand.

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Title: Drug resistance pattern in multidrug resistance pulmonary tuberculosis patients.

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Title: First- and second-line drug resistance patterns among previously treated tuberculosis patients in India.

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Title: Validation of the GenoType MTBDRplus assay for diagnosis of multidrug resistant tuberculosis in South Vietnam.

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Title: The thioamides methimazole and thiourea inhibit growth of M. avium Subspecies paratuberculosis in culture.

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Title: Multiple osseous involvements in a case of disseminated cryptococcosis.

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Title: [Adverse drug reactions in multidrug-resistant tuberculosis].

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Title: Simultaneously anterior decompression and posterior instrumentation by extrapleural retroperitoneal approach in thoracolumbar lesions.

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Title: Immune thrombocytopenia in a challenging case of disseminated tuberculosis: a case report and review of the literature.

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Title: Epidemic levels of drug resistant tuberculosis (MDR and XDR-TB) in a high HIV prevalence setting in Khayelitsha, South Africa.

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Title: Antituberculosis drugs: drug interactions, adverse effects, and use in special situations. Part 2: second line drugs.

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Title: [Tuberculosis of the tonsils].

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Title: Mining flexible-receptor docking experiments to select promising protein receptor snapshots.

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Title: Propylthiouracil-induced acute liver failure: role of liver transplantation.

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Title: A comparative analysis of the Libyan national essential medicines list and the WHO model list of essential medicines.

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Title: The use of anti-tuberculosis therapy for latent TB infection.

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Title: Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project.

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Title: Direct catalytic asymmetric aldol reactions of thioamides: toward a stereocontrolled synthesis of 1,3-polyols.

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Title: Synthesis and rearrangement of a bridged thioamide.

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Title: Regioselective synthesis of new 2-(E)-cyano(thiazolidin-2-ylidene)thiazoles.

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Title: Synthesis and antibacterial activity of some new thiazole and thiophene derivatives.

Journal: European journal of medicinal chemistry 20091101

Title: Ethionamide cross- and co-resistance in children with isoniazid-resistant tuberculosis.

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Title: 1-(4-Ethoxy-benzo-yl)-4-(4-methoxy-phen-yl)thiosemicarbazide.

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Title: Asymmetric transfer hydrogenation of ketones catalyzed by amino acid derived rhodium complexes: on the origin of enantioselectivity and enantioswitchability.

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Title: Fast-growing, non-infectious and intracellularly surviving drug-resistant Mycobacterium aurum: a model for high-throughput antituberculosis drug screening.

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Title: The essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2.

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Title: Molecular epidemiology and drug resistance of widespread genotypes of Mycobacterium tuberculosis in northwestern Russia.

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Title: Prevalence of extensively drug-resistant tuberculosis in Vladimir and Orel regions, Russia.

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Title: Evaluation of in vivo wound-healing potential of 2-[4-(2,4-dimethoxy-benzoyl)-phenoxy]-1-[4-(3-piperidin-4-yl-propyl)-piperidin-1-yl]-ethanone derivatives.

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Title: Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in iran.

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Title: ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria.

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Title: Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production.

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Title: 1-(4-Bromo-phen-yl)-1-(4-nitro-benzo-yl)thio-urea.

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Title: Palladium(0)-catalyzed, copper(i)-mediated coupling of cyclic thioamides with alkenylboronic acids, organostannanes, and siloxanes.

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Title: Radiometric vs. agar proportion methods for assessing ethionamide resistance and its clinical effects in multidrug-resistant tuberculosis.

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Title: Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis.

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Title: Extensively drug-resistant tuberculosis in the UK: 1995 to 2007.

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Title: Mycobacterium tuberculosis: drug resistance and future perspectives.

Journal: Future microbiology 20090601

Title: 3-Methyl-thio-benzamide.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: Rhodamine inhibitors of P-glycoprotein: an amide/thioamide 'switch' for ATPase activity.

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Title: Strategies for acquiring the phospholipid metabolite inositol in pathogenic bacteria, fungi and protozoa: making it and taking it.

Journal: Microbiology (Reading, England) 20090501

Title: The clinical relevance of Mycobacterial pharmacogenetics.

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Title: Synthetic EthR inhibitors boost antituberculous activity of ethionamide.

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Title: N'-[(2Z)-3-Allyl-4-oxo-1,3-thia-zolidin-2-yl-idene]-5-fluoro-3-phenyl-1H-indole-2-carbohydrazide.

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Title: 1-Furoyl-3-[3-(trifluoro-meth-yl)phen-yl]thio-urea.

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Title: N-(2-Furo-yl)-N'-(2-pyrid-yl)thio-urea.

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Title: Herbicidal activity of glucosinolate degradation products in fermented meadowfoam ( Limnanthes alba ) seed meal.

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Title: New antimony(III) bromide complexes with thioamides: synthesis, characterization, and cytostatic properties.

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Title: Thioamide hydroxypyrothiones supersede amide hydroxypyrothiones in potency against anthrax lethal factor.

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Title: A time-resolved spectroscopic comparison of the photoisomerization of small beta-turn-forming thioxopeptides.

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Title: Ionic liquid promoted preparation of 4H-thiopyran and pyrimidine nucleoside-thiopyran hybrids through one-pot multi-component reaction of thioamide.

Journal: Molecular diversity 20090201

Title: Tuberculosis pharmacotherapy: strategies to optimize patient care.

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Title: On the effect of tether composition on cis/trans selectivity in intramolecular Diels-Alder reactions.

Journal: Chemistry, an Asian journal 20090105

Title: Human flavin-containing monooxygenase 2.1 catalyzes oxygenation of the antitubercular drugs thiacetazone and ethionamide.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101

Title: Pincer thioamide and pincer thioimide palladium complexes catalyze highly efficient Negishi coupling of primary and secondary alkyl zinc reagents at room temperature.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

Title: Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin.

Journal: BMC microbiology 20090101

Title: Effects of Fructus Piperis Longi extract on fibrotic liver of gamma-irradiated rats.

Journal: Chinese medicine 20090101

Title: Correlations of mutations in katG, oxyR-ahpC and inhA genes and in vitro susceptibility in Mycobacterium tuberculosis clinical strains segregated by spoligotype families from tuberculosis prevalent countries in South America.

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Title: Clinical deterioration during antitubercular treatment at a district hospital in South Africa: the importance of drug resistance and AIDS defining illnesses.

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Title: Fluoromycobacteriophages for rapid, specific, and sensitive antibiotic susceptibility testing of Mycobacterium tuberculosis.

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Title: Synthesis, characterization, and biological studies of organotin(IV) derivatives with o- or p-hydroxybenzoic acids.

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Title: Synthesis, spectroscopic, and antimicrobial studies on bivalent zinc and mercury complexes of 2-formylpyridine thiosemicarbazone.

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Title: Direct catalytic asymmetric Mannich-type reaction of thioamides.

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Title: Molecular detection of rifampin and isoniazid resistance to guide chronic TB patient management in Burkina Faso.

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Title: Early outcomes of MDR-TB treatment in a high HIV-prevalence setting in Southern Africa.

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Title: The Differential Gene Expression Pattern of Mycobacterium tuberculosis in Response to Capreomycin and PA-824 versus First-Line TB Drugs Reveals Stress- and PE/PPE-Related Drug Targets.

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Title: Ambulatory-based standardized therapy for multi-drug resistant tuberculosis: experience from Nepal, 2005-2006.

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Title: Drug susceptibility testing of Mycobacterium tuberculosis against second-line drugs using the Bactec MGIT 960 System.

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Title: Nonplanar structures of thioamides derived from 7-azabicyclo[2.2.1]heptane. Electronically tunable planarity of thioamides.

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Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

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Title: Kinetic resolution of racemic alcohols using thioamide modified 1-methyl-histidine methyl ester.

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Title: Management of pediatric multidrug-resistant tuberculosis and latent tuberculosis infections in New York City from 1995 to 2003.

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Title: Recent Advances in Multi-Drug-Resistant Tuberculosis and RNTCP.

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Title: Synthesis and antiamoebic activity of metronidazole thiosemicarbazone analogues.

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Title: Ultrasound accelerated conversion of Nalpha-urethane protected peptide esters to their thiopeptides using P2S5.

Journal: Ultrasonics sonochemistry 20080901

Title: Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.

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Title: A biopersistence study following exposure to chrysotile asbestos alone or in combination with fine particles.

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Title: 1-(o-Tol-yl)thio-urea.

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Title: N-Phenyl-piperidine-1-carbothio-amide.

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Title: Structural diversity in the first metal complexes of 2,5-dicarboxamidopyrroles and 2,5-dicarbothioamidopyrroles.

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Title: 1-(2-Furo-yl)-3-(o-tol-yl)thio-urea.

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Title: N-(2-Furylcarbon-yl)piperidine-1-carbo-thio-amide.

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Title: Ethyl 4-(3-benzoyl-thio-ureido)benzoate.

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Title: 1-(4-Acetyl-phen-yl)-3-butyrylthio-urea.

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Title: Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636.

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Title: 1-(3-Cyano-phen-yl)-3-(2-furo-yl)thio-urea.

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Title: Ethyl 4-(3-butyrylthio-ureido)benzoate.

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Title: Effect of thioxopeptide bonds on alpha-helix structure and stability.

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Title: Gene expression profiling in rat liver treated with compounds inducing phospholipidosis.

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Title: Extensively drug-resistant tuberculosis, Lesotho.

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Title: 1-Furfuryl-3-furoylthio-urea.

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Title: Increasing antituberculosis drug resistance in the United Kingdom: analysis of National Surveillance Data.

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Title: Extensively drug-resistant tuberculosis, Taiwan.

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Title: Five-antituberculosis Drug-resistance Genes Detection Using Array System.

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Title: Organization of the mycobacterial cell wall: a nanoscale view.

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Title: Activity of twelve second-line antimicrobial agents against Mycobacterium tuberculosis in Taiwan.

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Title: Time-resolved infrared spectroscopy of thiopeptide isomerization and hydrogen-bond breaking.

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Title: Low levels of second-line drug resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Rwanda.

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Title: Bipodal 1,1'-acyl-3,3,3',3'-tetraalkylbis(thiourea) ligands with flexible C3, C4 and C6 spacer groups.

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Title: Ethionamide.

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Title: Biological studies of new organotin(IV) complexes of thioamide ligands.

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Title: [The effect of interventional therapy in multimodality treatment on multi-drug resistant pulmonary tuberculosis].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20080201

Title: Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy.

Journal: BMC pediatrics 20080101

Title: Evidence-based annotation of the malaria parasite's genome using comparative expression profiling.

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Title: [A case of multi-drug resistant tuberculosis showing psychiatric adverse effect by cycloserine].

Journal: Kekkaku : [Tuberculosis] 20080101

Title: Study of the role of Mce3R on the transcription of mce genes of Mycobacterium tuberculosis.

Journal: BMC microbiology 20080101

Title: Synthesis, characterization, and biological activity of N-methyl-2-(1H-1,2,3-benzotriazol-1-y1)-3-oxobutan- ethioamide complexes with some divalent metal (II) ions.

Journal: Bioinorganic chemistry and applications 20080101

Title: Crystal structure and antitumor activity of the novel zwitterionic complex of tri-n-butyltin(IV) with 2-thiobarbituric acid.

Journal: Bioinorganic chemistry and applications 20080101

Title: Synthesis, Spectroscopic, and Anticancerous Properties of Mixed Ligand Palladium(II) and Silver(I) Complexes with 4,6-Diamino-5-hydroxy-2-mercaptopyrimidine and 2,2'-Bipyridyl.

Journal: Metal-based drugs 20080101

Title: Extensively drug resistant tuberculosis in a high income country: a report of four unrelated cases.

Journal: BMC infectious diseases 20080101

Title: Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis.

Journal: PloS one 20080101

Title: Ability of online drug databases to assist in clinical decision-making with infectious disease therapies.

Journal: BMC infectious diseases 20080101

Title: Multidrug resistant tuberculosis co-existing with aspergilloma and invasive aspergillosis in a 50 year old diabetic woman: a case report.

Journal: Cases journal 20080101

Title: targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.

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Title: Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance.

Journal: BMC microbiology 20080101

Title: Genotyping and drug resistance patterns of M. tuberculosis strains in Pakistan.

Journal: BMC infectious diseases 20080101

Title: Synthesis, characterization, and in vitro cytotoxic activities of benzaldehyde thiosemicarbazone derivatives and their palladium (II) and platinum (II) complexes against various human tumor cell lines.

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Title: Tuberculosis of the breast.

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Title: N-Butyl-pyridine-4-thio-carboxamide.

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Title: 1-(1,3-Benzothia-zol-2-yl)-3-benzoyl-thio-urea.

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Title: (Z)-N-[2-(Dimethyl-ammonio)eth-yl]thio-acetamide chloride.

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Title: Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms.

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Title: A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis.

Journal: Molecular microbiology 20070801

Title: Comparative genomic analysis of mycobacteriophage Tweety: evolutionary insights and construction of compatible site-specific integration vectors for mycobacteria.

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Title: [Case of pulmonary multi-drug resistant tuberculosis with left destroyed lung, treated with pneumonectomy].

Journal: Kekkaku : [Tuberculosis] 20070701

Title: Current issues on molecular and immunological diagnosis of tuberculosis.

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Title: Palladium(0)-catalyzed, copper(I)-mediated coupling of boronic acids with cyclic thioamides. selective carbon-carbon bond formation for the functionalization of heterocycles.

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Title: Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.

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Title: Type II NADH: menaquinone oxidoreductase of Mycobacterium tuberculosis.

Journal: Infectious disorders drug targets 20070601

Title: Comparative kinetics of cofactor association and dissociation for the human and trypanosomal S-adenosylhomocysteine hydrolases. 1. Basic features of the association and dissociation processes.

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Journal: Emerging infectious diseases 20070501

Title: [Survey of anti-tuberculosis drug-induced severe liver injury in Japan].

Journal: Kekkaku : [Tuberculosis] 20070501

Title: Spread of extensively drug-resistant tuberculosis.

Journal: Emerging infectious diseases 20070401

Title: EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets.

Journal: Antimicrobial agents and chemotherapy 20070301

Title: Worldwide emergence of extensively drug-resistant tuberculosis.

Journal: Emerging infectious diseases 20070301

Title: [Treatment results of rifampicin (RFP) resistant isoniazid (INH) susceptible tuberculosis, a hospital based study].

Journal: Kekkaku : [Tuberculosis] 20070201

Title: [Late-occurring cutaneous vasculitis after successful treatment of diffuse lepromatous leprosy: Lucio's phenomenon].

Journal: Medecine tropicale : revue du Corps de sante colonial 20070201

Title: Mechanism of thioamide drug action against tuberculosis and leprosy.

Journal: The Journal of experimental medicine 20070122

Title: Crystal structure of Bacillus cereus HlyIIR, a transcriptional regulator of the gene for pore-forming toxin hemolysin II.

Journal: Journal of molecular biology 20070119

Title: Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis.

Journal: The Pediatric infectious disease journal 20070101

Title: Spectroscopic, thermal and biological studies on some trivalent ruthenium and rhodium NS chelating thiosemicarbazone complexes.

Journal: Bioinorganic chemistry and applications 20070101

Title: GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolism.

Journal: Genome biology 20070101

Title: M. tuberculosis genotypic diversity and drug susceptibility pattern in HIV-infected and non-HIV-infected patients in northern Tanzania.

Journal: BMC microbiology 20070101

Title: Docking of phosphonate and trehalose analog inhibitors into M. tuberculosis mycolyltransferase Ag85C: Comparison of the two scoring fitness functions GoldScore and ChemScore, in the GOLD software.

Journal: Bioinformation 20070101

Title: Lower-rim substituted calixarenes and their applications.

Journal: Bioinorganic chemistry and applications 20070101

Title: Susceptibility tests to second line drugs and re-treatment of tuberculosis revisiting early experiences.

Journal: Medicina 20070101

Title: Coexistence of hydrogen-bonded loop and extended tetrapeptide conformations.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: Multidrug-resistant tuberculosis treatment outcomes in Karakalpakstan, Uzbekistan: treatment complexity and XDR-TB among treatment failures.

Journal: PloS one 20070101

Title: Audiologic monitoring of multi-drug resistant tuberculosis patients on aminoglycoside treatment with long term follow-up.

Journal: BMC ear, nose, and throat disorders 20070101

Title: Drug resistance in Mycobacterium tuberculosis strains isolated from sputum samples from symptomatic outpatients: Complexo de Manguinhos, Rio de Janeiro, Brazil.

Journal: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 20070101

Title: Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

Journal: PloS one 20070101

Title: The first example of isomeric solid amide and its enol.

Journal: Organic letters 20061221

Title: Idiopathic palmar fasciitis with polyarthritis syndrome.

Journal: Journal of Korean medical science 20061201

Title: [Case of SIADH caused by ethionamide in a patient with pulmonary tuberculosis].

Journal: Kekkaku : [Tuberculosis] 20061201

Title: Synthesis and QSAR studies of novel triazole compounds containing thioamide as potential antifungal agents.

Journal: Bioorganic & medicinal chemistry 20061101

Title: Molecular characterization of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from the USA.

Journal: Journal of medical microbiology 20061101

Title: Thyroid disease in pregnancy.

Journal: Obstetrics and gynecology 20061101

Title: Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria.

Journal: The Journal of antimicrobial chemotherapy 20061001

Title: Predicting the efficiencies of 2-mercaptobenzothiazole collectors used as chelating agents in flotation processes: a density-functional study.

Journal: Journal of molecular modeling 20060901

Title: Designing amino acid residues with single-conformations.

Journal: Protein engineering, design & selection : PEDS 20060901

Title: Multidrug-resistant tuberculosis management in resource-limited settings.

Journal: Emerging infectious diseases 20060901

Title: Fluorogenic Hg2+-selective chemodosimeter derived from 8-hydroxyquinoline.

Journal: Organic letters 20060803

Title: [A controlled clinical trial of long course chemotherapy regimens containing rifabutin in the treatment of multi-drug resistant pulmonary tuberculosis].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20060801

Title: Modulated preparation and structural diversification of ZnII and CdII metal-organic frameworks with a versatile building block 5-(4-pyridyl)-1,3,4-oxadiazole-2-thiol.

Journal: Inorganic chemistry 20060724

Title: Prioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosis.

Journal: PLoS computational biology 20060601

Title: Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis.

Journal: PLoS pathogens 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis.

Journal: Tuberculosis (Edinburgh, Scotland) 20060301

Title: Exploring drug action on Mycobacterium tuberculosis using affymetrix oligonucleotide genechips.

Journal: Tuberculosis (Edinburgh, Scotland) 20060301

Title: A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy.

Journal: The American journal of tropical medicine and hygiene 20060301

Title: Pulmonary Mycobacterium kansasii infection in Israel, 1999-2004: clinical features, drug susceptibility, and outcome.

Journal: Chest 20060301

Title: Oxidative activation of thiacetazone by the Mycobacterium tuberculosis flavin monooxygenase EtaA and human FMO1 and FMO3.

Journal: Chemical research in toxicology 20060301

Title: API TB Consensus Guidelines 2006: Management of pulmonary tuberculosis, extra-pulmonary tuberculosis and tuberculosis in special situations.

Journal: The Journal of the Association of Physicians of India 20060301

Title: Thioamide pincer ligands with charge versatility.

Journal: Inorganic chemistry 20060206

Title: The first potent inhibitors for human glutaminyl cyclase: synthesis and structure-activity relationship.

Journal: Journal of medicinal chemistry 20060126

Title: Novel reactions of [60]fullerene with amino acid esters and carbon disulfide.

Journal: The Journal of organic chemistry 20060120

Title: Structure of thioviridamide, a novel apoptosis inducer from Streptomyces olivoviridis.

Journal: The Journal of antibiotics 20060101

Title: [The rates of resistance to second-line drugs in multidrug resistant Mycobacterium tuberculosis strains].

Journal: Mikrobiyoloji bulteni 20060101

Title: The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein.

Journal: Biomedical chromatography : BMC 20060101

Title: Genital tuberculosis in a tamoxifen-treated postmenopausal woman with breast cancer and bloody vaginal discharge.

Journal: Annals of clinical microbiology and antimicrobials 20060101

Title: Tuberculosis chemotherapy: current drug delivery approaches.

Journal: Respiratory research 20060101

Title: Interaction of thioamides, selenoamides, and amides with diiodine.

Journal: Bioinorganic chemistry and applications 20060101

Title: Pressure-tuning Raman spectra of diiodine thioamide compounds: models for antithyroid drug activity.

Journal: Bioinorganic chemistry and applications 20060101

Title: Efficacy and safety of kanamycin, ethionamide, PAS and cycloserine in multidrug-resistant pulmonary tuberculosis patients.

Journal: The Indian journal of chest diseases & allied sciences 20060101

Title: Synthesis of nitrogen and sulfur macrocycles with cis exogenous oxygen and sulfur donor atoms.

Journal: Organic & biomolecular chemistry 20051207

Title: Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model.

Journal: American journal of respiratory and critical care medicine 20051201

Title: Diagnosis and treatment of nontuberculous mycobacterial pulmonary diseases: a Korean perspective.

Journal: Journal of Korean medical science 20051201

Title: Synthesis, structural characterization, and computational studies of novel diiodine adducts with the heterocyclic thioamides N-methylbenzothiazole-2-thione and benzimidazole-2-thione: implications with the mechanism of action of antithyroid drugs.

Journal: Inorganic chemistry 20051114

Title: Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates.

Journal: Antimicrobial agents and chemotherapy 20051101

Title: Simple means to alleviate sensitivity loss by trifluoroacetic acid (TFA) mobile phases in the hydrophilic interaction chromatography-electrospray tandem mass spectrometric (HILIC-ESI/MS/MS) bioanalysis of basic compounds.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025

Title: Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates.

Journal: Journal of medical microbiology 20051001

Title: Flux balance analysis of mycolic acid pathway: targets for anti-tubercular drugs.

Journal: PLoS computational biology 20051001

Title: [Current situation of contacts examination and chemoprophylaxis for persons exposed to multi-drug resistant tuberculosis in ordinance-designated cities in Japan].

Journal: Kekkaku : [Tuberculosis] 20051001

Title: Ketoheterocycle-based inhibitors of cathepsin K: a novel entry into the synthesis of peptidic ketoheterocycles.

Journal: Bioorganic & medicinal chemistry letters 20050901

Title: [Resistance to antituberculous drugs].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20050801

Title: Oxidation of N-substituted dopamine derivatives: irreversible formation of a spirocyclic product.

Journal: Organic & biomolecular chemistry 20050707

Title: Hypothyroidism due to ethionamide.

Journal: The New England journal of medicine 20050630

Title: Differential network expression during drug and stress response.

Journal: Bioinformatics (Oxford, England) 20050615

Title: Monitoring of the ethionamide pro-drug activation in mycobacteria by (1)H high resolution magic angle spinning NMR.

Journal: Biochemical and biophysical research communications 20050603

Title: Altered expression profile of mycobacterial surface glycopeptidolipids following treatment with the antifungal azole inhibitors econazole and clotrimazole.

Journal: Microbiology (Reading, England) 20050601

Title: Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 3: 8-Thiocarboxamido and 8-thioformamido derivatives of cyclazocine.

Journal: Bioorganic & medicinal chemistry letters 20050516

Title: [Doping in the peloton of antituberculosis drugs].

Journal: Medecine sciences : M/S 20050401

Title: Resistance of multidrug-resistant strains of Mycobacterium tuberculosis from the Archangel oblast, Russia, to second-line anti-tuberculosis drugs.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20050301

Title: Mycobacterium tuberculosis drug resistance, Abkhazia.

Journal: Emerging infectious diseases 20050301

Title: Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs.

Journal: Journal of inorganic biochemistry 20050201

Title: Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.

Journal: Antimicrobial agents and chemotherapy 20050201

Title: Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050201

Title: Second-line drug susceptibilities of Thai multidrug-resistant Mycobacterium tuberculosis isolates.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050201

Title: Analysis of Mycobacterium tuberculosis isolates from treatment failure patients living in East Timor.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050101

Title: Capreomycin is active against non-replicating M. tuberculosis.

Journal: Annals of clinical microbiology and antimicrobials 20050101

Title: [Extrathoracic tuberculosis in Siberia and the Far East].

Journal: Problemy tuberkuleza i boleznei legkikh 20050101

Title: Axially dissymmetric N-thioacylated (S)-(-)-1,1'-binaphthyl-2,2'-diamine ligands for copper-catalyzed asymmetric Michael addition of diethylzinc to alpha,beta-unsaturated ketone.

Journal: Chirality 20041101

Title: Polymorphism and solvolysis of 2-cyano-3-[4-(N,N-diethylamino)phenyl]prop-2-enethioamide.

Journal: Acta crystallographica. Section C, Crystal structure communications 20041101

Title: Inhibitory effect of antituberculosis drugs on human cytochrome P450-mediated activities.

Journal: Journal of pharmacological sciences 20041101

Title: Drug susceptibility of Brazilian strains of Mycobacterium bovis using traditional and molecular techniques.

Journal: Memorias do Instituto Oswaldo Cruz 20041101

Title: Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis.

Journal: Molecular cell 20041022

Title: Multidrug resistant miliary tuberculosis and Pott's disease in an immunocompetent patient.

Journal: Saudi medical journal 20041001

Title: Mycobacterium triplex pulmonary disease in immunocompetent host.

Journal: Emerging infectious diseases 20041001

Title: Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spectrometry, and nanoelectrospray tandem mass spectrometry.

Journal: Chemical research in toxicology 20040901

Title: Outcome of treatment of multidrug resistant tuberculosis.

Journal: The Ceylon medical journal 20040901

Title: Pyridylthiocarbazide complexes of rhenium with potential radiopharmaceutical applications.

Journal: Dalton transactions (Cambridge, England : 2003) 20040821

Title: Synthesis and antibacterial activity of arylpiperazinyl oxazolidinones with diversification of the N-substituents.

Journal: Bioorganic & medicinal chemistry letters 20040802

Title: Antituberculous activity of some aryl semicarbazone derivatives.

Journal: Bioorganic & medicinal chemistry letters 20040802

Title: Pharmacy data for tuberculosis surveillance and assessment of patient management.

Journal: Emerging infectious diseases 20040801

Title: Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance.

Journal: Journal of molecular biology 20040723

Title: Surveillance of Mycobacterium tuberculosis susceptibility to second-line drugs in Hong Kong, 1995-2002, after the implementation of DOTS-plus.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040601

Title: Treatment and follow-up of HIV-negative multidrug-resistant tuberculosis patients in an infectious diseases reference hospital, Buenos Aires, Argentina.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040601

Title: Iatrogenic Mycobacterium simiae skin infection in an immunocompetent patient.

Journal: Emerging infectious diseases 20040501

Title: Use of MGIT 960 for rapid quantitative measurement of the susceptibility of Mycobacterium tuberculosis complex to ciprofloxacin and ethionamide.

Journal: The Journal of antimicrobial chemotherapy 20040401

Title: Synthesis and antimycobacterial activity of 1,2,4-triazole 3-benzylsulfanyl derivatives.

Journal: Farmaco (Societa chimica italiana : 1989) 20040401

Title: A microplate indicator-based method for determining the susceptibility of multidrug-resistant Mycobacterium tuberculosis to antimicrobial agents.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040201

Title: The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase.

Journal: The Journal of biological chemistry 20040130

Title: Computational study of conformational preferences of thioamide-containing azaglycine peptides.

Journal: Journal of computational chemistry 20040130

Title: Covalent binding of the 13C-labeled skin sensitizers 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI) to a model peptide and glutathione.

Journal: Bioorganic & medicinal chemistry letters 20040119

Title: New agents active against Mycobacterium avium complex selected by molecular topology: a virtual screening method.

Journal: The Journal of antimicrobial chemotherapy 20040101

Title: EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator.

Journal: Molecular microbiology 20040101

Title: A case study in Hansen's disease acquired after heart transplant.

Journal: Critical care nursing quarterly 20040101

Title: Adjuvant interferon gamma in patients with drug - resistant pulmonary tuberculosis: a pilot study.

Journal: BMC infectious diseases 20040101

Title: Pharmacokinetics and relative bioavailability of clofazimine in relation to food, orange juice and antacid.

Journal: Tuberculosis (Edinburgh, Scotland) 20040101

Title: Lepromatous leprosy in a heart transplant recipient.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20031201

Title: Kinetic spectrophotometric determination of some sulfur containing compounds in pharmaceutical preparations and human serum.

Journal: Farmaco (Societa chimica italiana : 1989) 20031201

Title: Invasive Mycobacterium marinum infections.

Journal: Emerging infectious diseases 20031101

Title: Reaction and characterization of thioamide dianions derived from N-benzyl thioamides.

Journal: The Journal of organic chemistry 20031031

Title: Evaluation of indirect susceptibility testing of Mycobacterium tuberculosis to the first- and second-line, and alternative drugs by the newer MB/BacT system.

Journal: Memorias do Instituto Oswaldo Cruz 20030901

Title: Gatifloxacin and ethionamide as the foundation for therapy of tuberculosis.

Journal: Antimicrobial agents and chemotherapy 20030801

Title: Chronic cases of tuberculosis in Casablanca, Morocco.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20030701

Title: Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.

Journal: The Journal of biological chemistry 20030606

Title: Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis.

Journal: Microbiology (Reading, England) 20030501

Title: Vibrational study of the secondary thioamide function, the intramolecular resonance assisted and intermolecular hydrogen bonding in NN'-hydroxyalkyl dithiooxamides.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030401

Title: Vibrational characterization of the tertiary amide and thioamide group.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030301

Title: Multidrug-resistant tuberculosis in pregnancy: case report and review of the literature.

Journal: Chest 20030301

Title: Mycobacterium celatum pulmonary infection in the immunocompetent: case report and review.

Journal: Emerging infectious diseases 20030301

Title: Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug-resistant Mycobacterium tuberculosis infection in BALB/c mice.

Journal: Antimicrobial agents and chemotherapy 20030101

Title: Vibrational characterization of the peptide bond.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030101

Title: Synthesis and pharmacological evaluation of new 1,2-dithiolane based antioxidants.

Journal: European journal of medicinal chemistry 20030101

Title: Preparation of thioamide building blocks via microwave-promoted three-component kindler reactions.

Journal: Journal of combinatorial chemistry 20030101

Title: The 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay as rapid colorimetric method for determination of antibiotic susceptibility of clinical Mycobacterium tuberculosis isolates in liquid medium.

Journal: Clinical laboratory 20030101

Title: Incorporation of antibiotics in liposomes designed for tuberculosis therapy by inhalation.

Journal: Drug delivery 20030101

Title: [A case of pulmonary multiresistant Mycobacterium bovis tuberculosis in Madagascar].

Journal: Archives de l'Institut Pasteur de Madagascar 20030101

Title: Conformational stability of helical peptides containing a thioamide linkage.

Journal: Organic letters 20021226

Title: 2-Pyridinethiol/2-pyridinethione tautomeric equilibrium. A comparative experimental and computational study.

Journal: The Journal of organic chemistry 20021213

Title: Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine.

Journal: Bioorganic & medicinal chemistry letters 20021202

Title: Heterocyclic benzazole derivatives with antimycobacterial in vitro activity.

Journal: Bioorganic & medicinal chemistry letters 20021118

Title: Molecular epidemiology of tuberculosis in a sentinel surveillance population.

Journal: Emerging infectious diseases 20021101

Title: Identifying the sources of tuberculosis in young children: a multistate investigation.

Journal: Emerging infectious diseases 20021101

Title: Molecular epidemiology of multidrug-resistant tuberculosis, New York City, 1995-1997.

Journal: Emerging infectious diseases 20021101

Title: High-pressure Fourier transform micro-Raman spectroscopic investigation of diiodine-heterocyclic thioamide adducts.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001

Title: Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis.

Journal: Molecular microbiology 20021001

Title: Diversity in the oxidation of substrates by cytochrome P450 2D6: lack of an obligatory role of aspartate 301-substrate electrostatic bonding.

Journal: Biochemistry 20020910

Title: Drugs that inhibit mycolic acid biosynthesis in Mycobacterium tuberculosis.

Journal: Current pharmaceutical biotechnology 20020901

Title: Inhibition of testosterone production by propylthiouracil in rat Leydig cells.

Journal: Biology of reproduction 20020801

Title: Long-term follow up of childhood tuberculous meningitis.

Journal: Developmental medicine and child neurology 20020801

Title: Feasibility and cost-effectiveness of standardised second-line drug treatment for chronic tuberculosis patients: a national cohort study in Peru.

Journal: Lancet (London, England) 20020608

Title: Transition metal complexes with thiosemicarbazide-based ligands. XLIII. Chlorobis(3-methylisoemicarbazide-kappa(2)N(1),N(4))zinc(II) chloride.

Journal: Acta crystallographica. Section C, Crystal structure communications 20020601

Title: Monothioacids as novel chelating groups. The Au(III) complexes of N-methylthioamide monothiooxamic acid.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020601

Title: Effects of thioamide substitutions on the conformation and stability of alpha- and 3(10)-helices.

Journal: Journal of the American Chemical Society 20020508

Title: [Medication-induced hepatic lesions in patients with pulmonary tuberculosis].

Journal: Voenno-meditsinskii zhurnal 20020501

Title: The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase.

Journal: The Journal of biological chemistry 20020412

Title: [Multicenter evaluation of a newly developed microdilution test, brothMIC NTM to determine minimum inhibitory concentrations of antimicrobial agents for nontuberculous mycobacteria].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20020401

Title: Direct sensitivity test of the MB/BacT system.

Journal: Memorias do Instituto Oswaldo Cruz 20020301

Title: First use of axially chiral thioamides for the stereocontrol of C-C bond formation.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20020202

Title: Comparative study on the use of solid media: Löwenstein-Jensen and Ogawa in the determination of anti-tuberculosis drug susceptibility.

Journal: Tuberculosis (Edinburgh, Scotland) 20020101

Title: Population pharmacokinetics of ethionamide in patients with tuberculosis.

Journal: Tuberculosis (Edinburgh, Scotland) 20020101

Title: Therapeutic drug monitoring in the treatment of tuberculosis.

Journal: Drugs 20020101

Title: Prevalence of acquired MDR-TB and HIV co-infection.

Journal: The Indian journal of chest diseases & allied sciences 20020101

Title: Toxicity assessment of 255 chemicals to pure cultured nitrifying bacteria using biosensor.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20020101

Title: Carbon-carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria.

Journal: Bioorganic & medicinal chemistry 20011201

Title: [Treatment outcomes of multidrug-resistant tuberculosis--comparison between success and failure cases].

Journal: Kekkaku : [Tuberculosis] 20011201

Title: Synthesis and anthelmintic activity of thioamide analogues of cyclic octadepsipeptides such as PF1022A.

Journal: Pest management science 20011101

Title: Pharmacokinetics of para-aminosalicylic acid granules under four dosing conditions.

Journal: The Annals of pharmacotherapy 20011101

Title: Synthesis and cytotoxicity of bis(benzo[g]indole-3-carboxamides) and related compounds.

Journal: Archiv der Pharmazie 20011101

Title: Compatibility of the thioamide functional group with beta-sheet secondary structure: incorporation of a thioamide linkage into a beta-hairpin peptide.

Journal: Organic letters 20011018

Title: [Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism].

Journal: Kekkaku : [Tuberculosis] 20011001

Title: Pharmacokinetics of cycloserine under fasting conditions and with high-fat meal, orange juice, and antacids.

Journal: Pharmacotherapy 20010801

Title: Synthesis, X-ray crystallographic structures of thio substituted N-acetyl N'-methylamide alanine and evaluation of sp sulfur parameters of the CFF91 force field.

Journal: The journal of peptide research : official journal of the American Peptide Society 20010701

Title: Efficacy and safety of sparfloxacin in combination with kanamycin and ethionamide in multidrug-resistant pulmonary tuberculosis patients: preliminary results.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20010601

Title: Ion interaction reagent reversed-phase high-performance liquid chromatography determination of anti-tuberculosis drugs and metabolites in biological fluids.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010425

Title: High-performance liquid chromatographic-tandem mass spectrometric method for the determination of ethionamide in human plasma, bronchoalveolar lavage fluid and alveolar cells.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010405

Title: Solvent effects on the thioamide rotational barrier: an experimental and theoretical study.

Journal: Journal of the American Chemical Society 20010307

Title: [Components of monitoring drug resistance of tuberculosis agent in the evaluation of effectiveness of the national tuberculosis control program].

Journal: Problemy tuberkuleza 20010101

Title: Synthesis of 3'-thioamido-modified 3'-deoxythymidine-5'-triphosphates and their use as chain terminators in Sanger-DNA sequencing.

Journal: Nucleosides, nucleotides & nucleic acids 20010101

Title: The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis.

Journal: Respiratory research 20010101

Title: Conformational analysis of thiopeptides: free energy calculations on the effects of thio-substitutions on the conformational distributions of alanine dipeptides.

Journal: Journal of molecular graphics & modelling 20010101

Title: Activation of the pro-drug ethionamide is regulated in mycobacteria.

Journal: The Journal of biological chemistry 20000908

Title: Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20000815

Title: Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis.

Journal: The Journal of biological chemistry 20000602

Title: Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs.

Journal: Biochemical pharmacology 20000201

Title: Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis.

Journal: Antimicrobial agents and chemotherapy 19990501

Title: NADH dehydrogenase defects confer isoniazid resistance and conditional lethality in Mycobacterium smegmatis.

Journal: Journal of bacteriology 19980501

Title: Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 19980501

Title: Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 19980201

Title: Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity.

Journal: Journal of natural products 19971201

Title: Genome and MIC stability in Mycobacterium tuberculosis and indications for continuation of use of isoniazid in multidrug-resistant tuberculosis.

Journal: Journal of medical microbiology 19971001

Title: Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium.

Journal: Antimicrobial agents and chemotherapy 19970501

Title: In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages.

Journal: Current microbiology 19960901

Title: Susceptibility testing of Mycobacterium avium complex isolates.

Journal: Antimicrobial agents and chemotherapy 19960801

Title: inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis.

Journal: Science (New York, N.Y.) 19940114

Title: Activity of subinhibitory concentrations of dapsone alone and in combination with cell-wall inhibitors against Mycobacterium avium complex organisms.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19931201

Title: Mycobacterium avium strains resistant to clarithromycin and azithromycin.

Journal: Antimicrobial agents and chemotherapy 19931101

Title: Spectrum of drugs against atypical mycobacteria: how valid is the current practice of drug susceptibility testing and the choice of drugs?

Journal: Zentralblatt fur Bakteriologie : international journal of medical microbiology 19921201

Title: Mycolic acid synthesis: a target for ethionamide in mycobacteria?

Journal: Antimicrobial agents and chemotherapy 19920601

Title: In vivo activities of newer rifamycin analogs against Mycobacterium avium infection.

Journal: Antimicrobial agents and chemotherapy 19911001

Title: Comparison of bacteriostatic and bactericidal activity of isoniazid and ethionamide against Mycobacterium avium and Mycobacterium tuberculosis.

Journal: The American review of respiratory disease 19910201

Title: [Antitubercular agents. 44. N,N-dialkyldithiooxamide].

Journal: Die Pharmazie 19881101

Title: MIC as a quantitative measurement of the susceptibility of Mycobacterium avium strains to seven antituberculosis drugs.

Journal: Antimicrobial agents and chemotherapy 19880801

Title: Qualitative and quantitative drug-susceptibility tests in mycobacteriology.

Journal: The American review of respiratory disease 19880501

Title: Determination of minimal inhibitory concentrations of antituberculosis drugs by radiometric and conventional methods.

Journal: The American review of respiratory disease 19870801

Title: Determination of MICs of conventional and experimental drugs in liquid medium by the radiometric method against Mycobacterium avium complex.

Journal: Drugs under experimental and clinical research 19870101

Title: In vitro antituberculosis activity of a new antibacterial substance ofloxacin (DL8280).

Journal: The American review of respiratory disease 19850301

Title: Benzylamines: synthesis and evaluation of antimycobacterial properties.

Journal: Journal of medicinal chemistry 19840901

Title: In vitro susceptibility of Mycobacterium avium complex and Mycobacterium tuberculosis strains to a spiro-piperidyl rifamycin.

Journal: The American review of respiratory disease 19820901

Title: Synergistic effect of rifampin, streptomycin, ethionamide, and ethambutol on Mycobacterium intracellulare.

Journal: The American review of respiratory disease 19820101

Title: In vitro and in vivo susceptibility of atypical mycobacteria to various drugs.

Journal: Reviews of infectious diseases 19810101

Title: Studies on pyrazine derivatives. Part X. Synthesis and tuberculostatic activity of some 6-cyclamino-, 6-imidazolyl--and triazolylpyrazine-2-carboxylic acids derivatives.

Journal: Polish journal of pharmacology and pharmacy 19780101

Title: [In-vitro potentiation of the anti-tuberculous effects of rifampicin and ethionamide by 4,4-diamino-diphenylsulphone (author's transl)].

Journal: Praxis der Pneumologie 19750801

Title: [Letter: Acute kidney failure due to rifampicin].

Journal: La Nouvelle presse medicale 19731110

Title: Protein synthesis in Mycobacterium tuberculosis H37Rv and the effect of streptomycin in streptomycin-susceptible and -resistant strains.

Journal: Antimicrobial agents and chemotherapy 19730901

Title: Toxic liver injuries.

Journal: Acta pathologica japonica 19730801

Title: [Experimental studies on the mechanism of fatty liver formation induced by ethionamide. V. Liver and serum total cholesterol in ethionamide-administered rats].

Journal: Kekkaku : [Tuberculosis] 19730301

Title: [Experimental studies on the mechanism of fatty liver formation induced by ethionamide. IV. Incorporation of (2- 14 C) acetate into the liver lipids of ethionamide-administered rats].

Journal: Kekkaku : [Tuberculosis] 19730101

Title: Reversible pellagra-like encephalopathy with ethionamide and cycloserine.

Journal: Tubercle 19720601

Title: [Treatment of lepromatous leprosy by ethionamide].

Journal: Maroc medical 19720301

Title: Effects of ethionamide and isoxyl on mycolic acid synthesis in Mycobacterium tuberculosis BCG.

Journal: Journal of general microbiology 19710601

Title: [Experimental studies on the mechanism of fatty liver formation induced by ethionamide. 3. Fatty acid composition of ethionamide-induced fatty liver and epididymal adipose tissue, and serum free fatty acid in ethionamide-administered rat].

Journal: Kekkaku : [Tuberculosis] 19700701

Title: [Experimental studies on the mechanism of fatty liver formation induced by ethionamide. II. Analysis of fatty acid composition of ethionamide-induced fatty liver in rat].

Journal: Kekkaku : [Tuberculosis] 19700401

Title: Results of treatment of pulmonary tuberculosis with cycloserine in association with other drugs.

Journal: Scandinavian journal of respiratory diseases. Supplementum 19700101

Title: [Neuropsychiatric incidences in antitubercular treatment consisting of isoniazid or isoniazid and ethionamide (8 cases)].

Journal: Annales medico-psychologiques 19690701

Title: [Experimental studies on the mechanism of fatty liver formation induced by ethionamide].

Journal: Kekkaku : [Tuberculosis] 19690401

Title: [Study on the adverse effects of secondary antituberculous drugs, with special reference to mental disorders induced by cycloserine and ethionamide].

Journal: Iryo 19690101

Title: Toxic liver damage due to ethionamide.

Journal: German medical monthly 19681201

Title: Experimental studies on therapeutic effects of various combinations of antituberculosis drugs. II. Comparison of various regimens in treatment of experimental mouse tuberculosis infected with SM- and INH-resistant Schacht strain.

Journal: The Japanese journal of tuberculosis 19670701

Title: Rifampicin: a new rifamycin. II. Laboratory studies on the antituberculous activity and preliminary clinical observations.

Journal: Arzneimittel-Forschung 19670501

Title: [Algo-dystrophy due to isoniazid and ethionamide].

Journal: Revue du rhumatisme et des maladies osteo-articulaires 19661201

Title: [Chemical studies the mechanism of action of isoniazid].

Journal: Arzneimittel-Forschung 19661101

Title: [2 cases of acute gastro-intestinal paralysis caused by 1314-TH].

Journal: Iryo 19661001

Title: The antituberculous activity of thioamide in vitro and in the experimental animal (mouse and guinea pig).

Journal: The American review of respiratory disease 19600501

Title: Vannelli, T.A., A. Dykman, and P.R. Ortiz de Montellano, The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase. J Biol Chem, 2002. 277(15): p. 12824-9.

Title: Quemard, A., G. Laneelle, and C. Lacave, Mycolic acid synthesis: a target for ethionamide in mycobacteria? Antimicrob Agents Chemother, 1992. 36(6): p. 1316-21.

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Tags:536-33-4 Molecular Formula|536-33-4 MDL|536-33-4 SMILES|536-33-4 4-Pyridinecarbothioamide, 2-ethyl-