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539-86-6,MFCD00468100
Catalog No.:AA00ILK4

539-86-6 | Allicin

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Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$43.00   $30.00
- +
25g
97% (isomers mixture)
in stock  
$86.00   $61.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ILK4
Chemical Name:
Allicin
CAS Number:
539-86-6
Molecular Formula:
C6H10OS2
Molecular Weight:
162.2730
MDL Number:
MFCD00468100
SMILES:
C=CCSS(=O)CC=C
NSC Number:
707388
Properties
Properties
 
BP:
248.6°C at 760 mmHg  
Form:
Liquid  
MP:
25°C  
Refractive Index:
nD20 1.561  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
120  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.3  

Downstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1947,vol.69,p.1711    JournaloftheAmericanChemicalSociety,1949,vol.71,p.3566

[1]JournaloftheAmericanChemicalSociety,1947,vol.69,p.1711    JournaloftheAmericanChemicalSociety,1949,vol.71,p.3566

[1]Patent:WO2012/76016,2012,A1.Locationinpatent:Page/Pagecolumn18

[2]Molecules,2017,vol.22

[3]JournaloftheAmericanChemicalSociety,1986,vol.108,p.7045

[4]EuropeanJournalofOrganicChemistry,2018,vol.2018,p.2134-2137

[5]BioorganicandMedicinalChemistryLetters,2010,vol.20,p.5541-5543

[6]InternationalJournalofMolecularSciences,2016,vol.17

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[10]Experientia,1947,vol.3,p.114    HelveticaChimicaActa,1949,vol.32,p.198

[11]JournaloftheAmericanChemicalSociety,1947,vol.69,p.1711    JournaloftheAmericanChemicalSociety,1949,vol.71,p.3566

[12]JournaloftheAmericanChemicalSociety,1984,vol.106,p.8295-8296

[13]JournalofOrganicChemistry,1994,vol.59,p.3227-3229

[14]JournalofAgriculturalandFoodChemistry,1995,vol.43,p.2332-2338

[15]EuropeanJournalofPharmacology,1995,vol.276,p.21-26

[16]Pharmazie,2004,vol.59,p.10-14

[17]Patent:US2005/260250,2005,A1.Locationinpatent:Page/Pagecolumn25;Sheet7

[18]Patent:US2005/260250,2005,A1.Locationinpatent:Page/Pagecolumn25;Sheet7

[19]AngewandteChemie-InternationalEdition,2009,vol.48,p.157-160

[20]Patent:WO2010/100486,2010,A2.Locationinpatent:Page/Pagecolumn26

[21]JournalofAgriculturalandFoodChemistry,2010,vol.58,p.11226-11233

[22]JournalofAgriculturalandFoodChemistry,2015,vol.63,p.787-794

[23]JournalofBiologicalChemistry,2016,vol.291,p.11477-11490

[24]InternationalJournalofMolecularSciences,2017,vol.18

[25]Molecules,2019,vol.24

[1]JournaloftheAmericanChemicalSociety,1945,vol.67,p.1032

[2]Experientia,1947,vol.3,p.114    HelveticaChimicaActa,1949,vol.32,p.198

[3]Patent:WO2010/100486,2010,A2.Locationinpatent:Page/Pagecolumn22-23

[4]Phytochemistry,2011,vol.72,p.1939-1946

[1]CurrentPatentAssignee:FUDANUNIVERSITY-CN111484413,2020,ALocationinpatent:Paragraph0116-0118

[2]Cavallito;Buck;Suter[JournaloftheAmericanChemicalSociety,1944,vol.66,p.1952]

[3]He,Yanting;Zhao,Yalei;Feng,Yuchen;Ren,Anqi;Zhang,Yunyi;Wang,Yang;Li,Hong[EuropeanJournalofPharmacology,2020,vol.869]

Literature

Title: Activation of the Nrf2 Signaling Pathway Involving KLF9 Plays a Critical Role in Allicin Resisting Against Arsenic Trioxide-Induced Hepatotoxicity in Rats.

Journal: Biological trace element research 20170301

Title: Allicin alleviates inflammation of trinitrobenzenesulfonic acid-induced rats and suppresses P38 and JNK pathways in Caco-2 cells.

Journal: Mediators of inflammation 20150101

Title: S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin.

Journal: Leukemia research 20121201

Title: Disrupted intracellular redox balance of the diplomonad fish parasite Spironucleus vortens by 5-nitroimidazoles and garlic-derived compounds.

Journal: Veterinary parasitology 20121123

Title: Neuroprotective effects of allicin on spinal cord ischemia-reperfusion injury via improvement of mitochondrial function in rabbits.

Journal: Neurochemistry international 20121001

Title: Lead compound design for TPR/COX dual inhibition.

Journal: Journal of molecular modeling 20120901

Title: Protective effect of allicin against acrylamide-induced hepatocyte damage in vitro and in vivo.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

Title: Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway.

Journal: Oncology reports 20120701

Title: Thiol-reactive compounds from garlic inhibit the epithelial sodium channel (ENaC).

Journal: Bioorganic & medicinal chemistry 20120701

Title: Allicin protects against myocardial apoptosis and fibrosis in streptozotocin-induced diabetic rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120615

Title: Studies on purification of allicin by molecular distillation.

Journal: Journal of the science of food and agriculture 20120501

Title: Preparation of encapsulated alliinase in alginate microparticles.

Journal: Biotechnology letters 20120301

Title: Transformation of synthetic allicin: the influence of ultrasound, microwaves, different solvents and temperatures, and the products isolation.

Journal: TheScientificWorldJournal 20120101

Title: Quantitative and qualitative analysis of the antifungal activity of allicin alone and in combination with antifungal drugs.

Journal: PloS one 20120101

Title: Allicin enhances host pro-inflammatory immune responses and protects against acute murine malaria infection.

Journal: Malaria journal 20120101

Title: Cholesterol-lowering effect of allicin on hypercholesterolemic ICR mice.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Comparison between allicin and fluconazole in Candida albicans biofilm inhibition and in suppression of HWP1 gene expression.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20111215

Title: Expression analysis of SIR2 and SAPs1-4 gene expression in Candida albicans treated with allicin compared to fluconazole.

Journal: Tropical biomedicine 20111201

Title: Garlic allicin as a potential agent for controlling oral pathogens.

Journal: Journal of medicinal food 20111101

Title: Low-frequency and low-intensity ultrasound accelerates alliinase-catalysed synthesis of allicin in freshly crushed garlic.

Journal: Journal of the science of food and agriculture 20110815

Title: [The utilization of omegalicin in treatment of psoriasis].

Journal: Klinicheskaia laboratornaia diagnostika 20110701

Title: S-allylmercapto-N-acetylcysteine up-regulates cellular glutathione and protects vascular endothelial cells from oxidative stress.

Journal: Free radical biology & medicine 20110501

Title: Effect of traditional Chinese medicinal herbs on Candida spp. from patients with HIV/AIDS.

Journal: Advances in dental research 20110401

Title: Allicin from garlic neutralizes the hemolytic activity of intra- and extra-cellular pneumolysin O in vitro.

Journal: Toxicon : official journal of the International Society on Toxinology 20110315

Title: Anticancer effects of garlic and garlic-derived compounds for breast cancer control.

Journal: Anti-cancer agents in medicinal chemistry 20110301

Title: Comparison between efficacy of allicin and fluconazole against Candida albicans in vitro and in a systemic candidiasis mouse model.

Journal: FEMS microbiology letters 20110201

Title: Efficacy of allicin from garlic against Ascaridia galli infection in chickens.

Journal: Poultry science 20110201

Title: [Protective effect of allicin on human periodontal ligament cells with nicotine-induced oxidative damage].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20110201

Title: Complementary and alternative medicine for prevention and treatment of the common cold.

Journal: Canadian family physician Medecin de famille canadien 20110101

Title: Ultrastructural study on the morphological changes to male worms of Schistosoma mansoni after in vitro exposure to allicin.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20110101

Title: Pharmacodynamic and Pharmacokinetic Interactions of Propranolol with Garlic (Allium sativum) in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Allicin disrupts the cell's electrochemical potential and induces apoptosis in yeast.

Journal: Free radical biology & medicine 20101215

Title: Allicin protects against cardiac hypertrophy and fibrosis via attenuating reactive oxygen species-dependent signaling pathways.

Journal: The Journal of nutritional biochemistry 20101201

Title: Dependence of vacuole disruption and independence of potassium ion efflux in fungicidal activity induced by combination of amphotericin B and allicin against Saccharomyces cerevisiae.

Journal: The Journal of antibiotics 20101201

Title: Allicin induces apoptosis in gastric cancer cells through activation of both extrinsic and intrinsic pathways.

Journal: Oncology reports 20101201

Title: Allicin can reduce neuronal death and ameliorate the spatial memory impairment in Alzheimer's disease models.

Journal: Neurosciences (Riyadh, Saudi Arabia) 20101001

Title: Allicin and derivates are cysteine protease inhibitors with antiparasitic activity.

Journal: Bioorganic & medicinal chemistry letters 20100915

Title: Inhibition of streptolysin O by allicin - an active component of garlic.

Journal: Journal of medical microbiology 20100901

Title: Allicin-induced global gene expression profile of Saccharomyces cerevisiae.

Journal: Applied microbiology and biotechnology 20100901

Title: Antioxidant and anticancer properties and mechanisms of inorganic selenium, oxo-sulfur, and oxo-selenium compounds.

Journal: Cell biochemistry and biophysics 20100901

Title: Garlic derivatives (PTS and PTS-O) differently affect the ecology of swine faecal microbiota in vitro.

Journal: Veterinary microbiology 20100729

Title: Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

Journal: Journal of medicinal chemistry 20100722

Title: Antigenotoxic effect of allicin against estradiol-17beta-induced genotoxic damage in cultured mammalian cells.

Journal: Natural product research 20100701

Title: S-allyl-mercapto-captopril: a novel compound in the treatment of Cohen-Rosenthal diabetic hypertensive rats.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20100601

Title: Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules.

Journal: European journal of medicinal chemistry 20100501

Title: In vitro investigation of antifungal activity of allicin alone and in combination with azoles against Candida species.

Journal: Mycopathologia 20100401

Title: A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation.

Journal: Molecular pharmacology 20100401

Title: In vitro and in vivo interactions between fluconazole and allicin against clinical isolates of fluconazole-resistant Candida albicans determined by alternative methods.

Journal: FEMS immunology and medical microbiology 20100301

Title: Individual and combined effect of meso-2,3-dimercaptosuccinic acid and allicin on blood and tissue lead content in mice.

Journal: Planta medica 20100201

Title: Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.

Journal: Neuroscience research 20100101

Title: Targeted yeast vacuole disruption by polyene antibiotics with a macrocyclic lactone ring.

Journal: International journal of antimicrobial agents 20100101

Title: Allicin purified from fresh garlic cloves induces apoptosis in colon cancer cells via Nrf2.

Journal: Nutrition and cancer 20100101

Title: The effect of combination therapy of allicin and fenofibrate on high fat diet-induced vascular endothelium dysfunction and liver damage in rats.

Journal: Lipids in health and disease 20100101

Title: Dietary phytochemicals and human health.

Journal: Advances in experimental medicine and biology 20100101

Title: Nutraceutical use of garlic sulfur-containing compounds.

Journal: Advances in experimental medicine and biology 20100101

Title: Peroxyl-radical-scavenging activity of garlic: 2-propenesulfenic acid versus allicin.

Journal: The journal of physical chemistry. B 20091210

Title: The vacuole-targeting fungicidal activity of amphotericin B against the pathogenic fungus Candida albicans and its enhancement by allicin.

Journal: The Journal of antibiotics 20091201

Title: [Allicin enhances cytotoxicity of CPT-11 to colon cancer LoVo cell in vitro].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

Title: Allicin and disulfiram enhance platelet integrin alphaIIbbeta3-fibrinogen binding.

Journal: Thrombosis research 20090901

Title: Antibacterial potential of garlic-derived allicin and its cancellation by sulfhydryl compounds.

Journal: Bioscience, biotechnology, and biochemistry 20090901

Title: [Metabonomic study on the effects of allicin on rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20090901

Title: Effects of allicin on CYP2C19 and CYP3A4 activity in healthy volunteers with different CYP2C19 genotypes.

Journal: European journal of clinical pharmacology 20090601

Title: Allicin up-regulates cellular glutathione level in vascular endothelial cells.

Journal: European journal of nutrition 20090301

Title: Allicin enhances the oxidative damage effect of amphotericin B against Candida albicans.

Journal: International journal of antimicrobial agents 20090301

Title: Novel derivatives of 6-mercaptopurine: synthesis, characterization and antiproliferative activities of S-allylthio-mercaptopurines.

Journal: European journal of medicinal chemistry 20090201

Title: Enhancement of the fungicidal activity of amphotericin B by allicin: effects on intracellular ergosterol trafficking.

Journal: Planta medica 20090201

Title: Anti-fungal efficacy of polybutylcyanoacrylate nanoparticles of allicin and comparison with pure allicin.

Journal: Journal of biomaterials science. Polymer edition 20090101

Title: Disulfide-mediated apoptosis of human T-lymphotrophc virus type-I (HTLV-I)-infected cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis.

Journal: Antiviral therapy 20090101

Title: Allicin, a major component of garlic, inhibits apoptosis in vital organs in rats with trauma/hemorrhagic shock.

Journal: Critical care medicine 20081201

Title: Thermostability of allicin determined by chemical and biological assays.

Journal: Bioscience, biotechnology, and biochemistry 20081101

Title: Observation of allicin-cysteine complex by reactive desorption electrospray ionization mass spectrometry for garlic.

Journal: Rapid communications in mass spectrometry : RCM 20081001

Title: Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells.

Journal: The Journal of nutritional biochemistry 20080801

Title: Synthesis, DNA binding, and cytotoxic evaluation of new analogs of diallyldisulfide, an active principle of garlic.

Journal: Bioorganic & medicinal chemistry 20080801

Title: Biological and chemical stability of garlic-derived allicin.

Journal: Journal of agricultural and food chemistry 20080611

Title: Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity.

Journal: European journal of applied physiology 20080601

Title: A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic.

Journal: Nature neuroscience 20080301

Title: In vitro bactericidal activity of allicin combined with cefoperazone, tobramycin and ciprofloxacin.

Journal: International journal of antimicrobial agents 20080201

Title: Improving knowledge of garlic paste greening through the design of an experimental strategy.

Journal: Journal of agricultural and food chemistry 20071212

Title: Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.

Journal: European journal of pharmacology 20071208

Title: Validated liquid chromatographic method for quantitative determination of allicin in garlic powder and tablets.

Journal: Journal of separation science 20071101

Title: Reactive sulfur species: kinetics and mechanism of the hydrolysis of cysteine thiosulfinate ester.

Journal: Chemical research in toxicology 20070901

Title: 4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20070814

Title: Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome.

Journal: American journal of hypertension 20070801

Title: Amplification of vacuole-targeting fungicidal activity of antibacterial antibiotic polymyxin B by allicin, an allyl sulfur compound from garlic.

Journal: The Journal of antibiotics 20070801

Title: Allicin inhibits cell polarization, migration and division via its direct effect on microtubules.

Journal: Cell motility and the cytoskeleton 20070501

Title: Antibacterial activity of allicin alone and in combination with beta-lactams against Staphylococcus spp. and Pseudomonas aeruginosa.

Journal: The Journal of antibiotics 20070501

Title: Allicin-induced suppression of Mycobacterium tuberculosis 85B mRNA in human monocytes.

Journal: Biochemical and biophysical research communications 20070406

Title: Effect of different plant extracts and natural substances (PENS) against membrane damage induced by enterotoxigenic Escherichia coli K88 in pig intestinal cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070301

Title: Effect of cooking on garlic (Allium sativum L.) antiplatelet activity and thiosulfinates content.

Journal: Journal of agricultural and food chemistry 20070221

Title: Effects of garlic oil on platelet aggregation: a double-blind placebo-controlled crossover study.

Journal: Platelets 20070201

Title: Induction of total insensitivity to capsaicin and hypersensitivity to garlic extract in human by decreased expression of TRPV1.

Journal: Neuroscience letters 20070110

Title: Determination of added sulfites in dried garlic with a modified version of the optimized Monier-Williams method.

Journal: Journal of AOAC International 20070101

Title: Fungitoxicity of lyophilized and spray-dried garlic extracts.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20070101

Title: Kinetic and mechanistic studies of allicin as an antioxidant.

Journal: Organic & biomolecular chemistry 20061121

Title: Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Enhancement of the fungicidal activity of amphotericin B by allicin, an allyl-sulfur compound from garlic, against the yeast Saccharomyces cerevisiae as a model system.

Journal: Planta medica 20061001

Title: Dependence of synergistic fungicidal activity of Cu2+ and allicin, an allyl sulfur compound from garlic, on selective accumulation of the ion in the plasma membrane fraction via allicin-mediated phospholipid peroxidation.

Journal: Planta medica 20060801

Title: Protective effects of garlic sulfur compounds against DNA damage induced by direct- and indirect-acting genotoxic agents in HepG2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060601

Title: [Ajoene the main active compound of garlic (Allium sativum): a new antifungal agent].

Journal: Revista iberoamericana de micologia 20060601

Title: Suppression of Mycobacterium tuberculosis induced reactive oxygen species (ROS) and TNF-alpha mRNA expression in human monocytes by allicin.

Journal: FEBS letters 20060501

Title: A method for continuous production of allicin using immobilized alliinase.

Journal: Analytical biochemistry 20060401

Title: Identification of two novel pigment precursors and a reddish-purple pigment involved in the blue-green discoloration of onion and garlic.

Journal: Journal of agricultural and food chemistry 20060208

Title: The antioxidant properties of garlic compounds: allyl cysteine, alliin, allicin, and allyl disulfide.

Journal: Journal of medicinal food 20060101

Title: Allicin, a major component of garlic, inhibits apoptosis of macrophage in a depleted nutritional state.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20060101

Title: The effects of S-allylmercaptocaptopril, the synthetic product of allicin and captopril, on cardiovascular risk factors associated with the metabolic syndrome.

Journal: Atherosclerosis 20051201

Title: Effect of garlic oil and four of its compounds on rumen microbial fermentation.

Journal: Journal of dairy science 20051201

Title: Synergistic fungicidal activity of Cu(2+) and allicin, an allyl sulfur compound from garlic, and its relation to the role of alkyl hydroperoxide reductase 1 as a cell surface defense in Saccharomyces cerevisiae.

Journal: Toxicology 20051115

Title: Thiolsulfinate allicin from garlic: inspiration for a new antimicrobial agent.

Journal: Annals of the New York Academy of Sciences 20051101

Title: Protective role of allicin and L-ascorbic acid against the genotoxic damage induced by chlormadinone acetate in cultured human lymphocytes.

Journal: Indian journal of experimental biology 20050901

Title: Pungent products from garlic activate the sensory ion channel TRPA1.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20050823

Title: Composition, stability, and bioavailability of garlic products used in a clinical trial.

Journal: Journal of agricultural and food chemistry 20050810

Title: Antigenotoxic effect of allicin against methyl methanesulphonate induced genotoxic damage.

Journal: Journal of environmental biology 20050701

Title: Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA.

Journal: Cancer letters 20050616

Title: Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20050601

Title: The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.

Journal: Current biology : CB 20050524

Title: Synthesis of 3-alkylthio-6-allylthiopyridazine derivatives and their antihepatocarcinoma activity.

Journal: Archives of pharmacal research 20050401

Title: Allicin and allicin-derived garlic compounds increase breath acetone through allyl methyl sulfide: use in measuring allicin bioavailability.

Journal: Journal of agricultural and food chemistry 20050323

Title: [The effect of cell killing and apoptosis by human herpes simplex virus- thymidine kinase/ganciclovir system combined with allitride in BIU87 cells].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20050315

Title: An overview of the antifungal properties of allicin and its breakdown products--the possibility of a safe and effective antifungal prophylactic.

Journal: Mycoses 20050301

Title: Use of a substrate/alliinase combination to generate antifungal activity in situ.

Journal: Journal of agricultural and food chemistry 20050209

Title: Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate.

Journal: Molecular cancer therapeutics 20050201

Title: Antioxidant activity of thiosulfinates derived from garlic.

Journal: Redox report : communications in free radical research 20050101

Title: The antiatherogenic effect of allicin: possible mode of action.

Journal: Pathobiology : journal of immunopathology, molecular and cellular biology 20050101

Title: Bis[3-(4'-substituted phenyl)prop-2-ene]disulfides as a new class of antihyperlipidemic compounds.

Journal: Bioorganic & medicinal chemistry letters 20041101

Title: Allylthiosulfinate: beta-cyclodextrin inclusion complex: preparation, characterization and microbiological activity.

Journal: Die Pharmazie 20041101

Title: [Effects of sulfur on physiological and biochemical indices and nutrition quality of garlic].

Journal: Ying yong sheng tai xue bao = The journal of applied ecology 20041101

Title: [3H]Allicin: preparation and applications.

Journal: Analytical biochemistry 20040815

Title: Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis.

Journal: The Journal of antimicrobial chemotherapy 20040501

Title: Antigenotoxic effect of allicin against SCEs induced by methyl methanesulphonate in cultured mammalian cells.

Journal: Indian journal of experimental biology 20040401

Title: Quantitative determination of allicin in garlic: supercritical fluid extraction and standard addition of alliin.

Journal: Journal of agricultural and food chemistry 20040225

Title: Hepatoprotective effect of allicin on tissue defense system in galactosamine/endotoxin challenged rats.

Journal: Journal of ethnopharmacology 20040101

Title: Allylmercaptocaptopril: a new antihypertensive drug.

Journal: American journal of hypertension 20040101

Title: Thermal degradation of allicin in garlic extracts and its implication on the inhibition of the in-vitro growth of Helicobacter pylori.

Journal: Biotechnology progress 20040101

Title: Mechanism and kinetics of synthesis of allicin.

Journal: Die Pharmazie 20040101

Title: Antibacterial activity of a new, stable, aqueous extract of allicin against methicillin-resistant Staphylococcus aureus.

Journal: British journal of biomedical science 20040101

Title: In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity.

Journal: American journal of therapeutics 20040101

Title: The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats.

Journal: American journal of hypertension 20031201

Title: Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery.

Journal: Molecular cancer therapeutics 20031201

Title: Stabilization of a metastable state of Torpedo californica acetylcholinesterase by chemical chaperones.

Journal: Protein science : a publication of the Protein Society 20031001

Title: Inactivation of jack bean urease by allicin.

Journal: Journal of enzyme inhibition and medicinal chemistry 20031001

Title: Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers.

Journal: Clinical pharmacology and therapeutics 20030801

Title: No effect of garlic extract supplement on serum lipid levels in hypercholesterolemic subjects.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030801

Title: High-performance ion-pair chromatography method for simultaneous analysis of alliin, deoxyalliin, allicin and dipeptide precursors in garlic products using multiple mass spectrometry and UV detection.

Journal: Journal of chromatography. A 20030328

Title: Modulation of TNF-alpha-induced ICAM-1 expression, NO and H2O2 production by alginate, allicin and ascorbic acid in human endothelial cells.

Journal: Archives of pharmacal research 20030301

Title: Determination of sulfite in dried garlic by reversed-phase ion-pairing liquid chromatography with post-column detection.

Journal: Journal of AOAC International 20030101

Title: Allicin suppresses the production of oxygen radicals by human neutrophils induced by various stimulating agents.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20030101

Title: In vitro activity of allicin against Staphylococcus epidermidis and influence of subinhibitory concentrations on biofilm formation.

Journal: Journal of applied microbiology 20030101

Title: [PCR in evaluating the effect of allicin and its combination with SMZco on murine toxoplamosis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20030101

Title: In vivo metabolism of diallyl disulphide in the rat: identification of two new metabolites.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20021201

Title: Garlic supplements and saquinavir.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020801

Title: A spectrophotometric assay for allicin, alliin, and alliinase (alliin lyase) with a chromogenic thiol: reaction of 4-mercaptopyridine with thiosulfinates.

Journal: Analytical biochemistry 20020801

Title: Garlic attenuates nitric oxide production in rat cardiac myocytes through inhibition of inducible nitric oxide synthase and the arginine transporter CAT-2 (cationic amino acid transporter-2).

Journal: Clinical science (London, England : 1979) 20020501

Title: Growth and health of Holstein calves fed milk replacers supplemented with antibiotics or Enteroguard.

Journal: Journal of dairy science 20020401

Title: Altered cytokeratin expression during chemoprevention of experimental hamster buccal pouch carcinogenesis by garlic.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20020301

Title: Garlic and its active metabolite allicin produce endothelium- and nitric oxide-dependent relaxation in rat pulmonary arteries.

Journal: Clinical and experimental pharmacology & physiology 20020101

Title: Computer automated prediction of potential therapeutic and toxicity protein targets of bioactive compounds from Chinese medicinal plants.

Journal: The American journal of Chinese medicine 20020101

Title: Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine.

Journal: Nutrition and cancer 20020101

Title: Effect of allicin on Ca2+ responses of human lymphocytes.

Journal: Doklady. Biochemistry and biophysics 20020101

Title: Hypocholesterolemic effect of an enteric-coated garlic supplement.

Journal: Journal of the American College of Nutrition 20010601

Title: Low allicin release from garlic supplements: a major problem due to the sensitivities of alliinase activity.

Journal: Journal of agricultural and food chemistry 20010501

Title: The effects of allicin and enalapril in fructose-induced hyperinsulinemic hyperlipidemic hypertensive rats.

Journal: American journal of hypertension 20010401

Title: Allicin release under simulated gastrointestinal conditions from garlic powder tablets employed in clinical trials on serum cholesterol.

Journal: Planta medica 20010201

Title: Helicobacter pylori eradication with beta carotene, ascorbic acid and allicin.

Journal: Acta medica (Hradec Kralove) 20010101

Title: Effects of an allicin-based product on cryptosporidiosis in neonatal calves.

Journal: Journal of the American Veterinary Medical Association 19980401

Title: Rahman, et al. Allicin and Other Functional Active Components in Garlic: Health Benefits and Bioavailability[J International Journal of Food Properties, 2007, 10(2):245-268.

Title: Müller A, et al. Allicin Induces Thiol Stress in Bacteria through S-Allylmercapto Modification of ProteinCysteines. J Biol Chem. 2016 May 27;291(22):11477-90.

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