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541-91-3,MFCD00211114
Catalog No.:AA00I9KZ

541-91-3 | Muscone

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Purity
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Price(USD)
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50mg
≥98%
in stock  
$63.00   $44.00
- +
250mg
97%
in stock  
$74.00   $52.00
- +
1g
97%
in stock  
$149.00   $104.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I9KZ
Chemical Name:
Muscone
CAS Number:
541-91-3
Molecular Formula:
C16H30O
Molecular Weight:
238.4088
MDL Number:
MFCD00211114
SMILES:
CC1CCCCCCCCCCCCC(=O)C1
FEMA Number:
3434
Properties
Properties
 
BP:
329.5°C at 760 mmHg  
Form:
Liquid  
MP:
33°C  
Refractive Index:
1.4770 to 1.4810  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
198  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
6.2  

Literature

Title: Muscone exerts neuroprotection in an experimental model of stroke via inhibition of the fas pathway.

Journal: Natural product communications 20120801

Title: Efficient macrocyclization by a novel oxy-oxonia-Cope reaction: synthesis and olfactory properties of new macrocyclic musks.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120604

Title: Induction of cytochrome P450 3A by Shexiang Baoxin Pill and its main components.

Journal: Chemico-biological interactions 20120125

Title: Antitumor and anti-invasive effects of diverse musk-fragrant macrocyclic ketones and their enhancement by hyperthermia.

Journal: Molecular medicine reports 20120101

Title: Fragrance material review on 3-methyl-1-cyclopentadecanone.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

Title: Fragrance material review on 3-methylcyclopentadecenone (mixed isomers).

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

Title: A toxicological and dermatological assessment of macrocyclic ketones when used as fragrance ingredients: the RIFM Expert Panel.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111201

Title: Protective effects of muscone on ischemia-reperfusion injury in cardiac myocytes.

Journal: Journal of ethnopharmacology 20111031

Title: Catalytic asymmetric Michael reactions of α,β-unsaturated ketones with sulfonyl-containing nucleophiles: chiral synthesis of (R)-muscone and (S)-celery ketone.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110110

Title: Muscone protects vertebral end-plate degeneration by antiinflammatory property.

Journal: Clinical orthopaedics and related research 20100601

Title: [Protective effects and machanism of muskone on pheochromocytoma cell injure induced by glutamate].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090701

Title: Comparison of the therapeutic effects of different compositions of muskone in the treatment of experimental myocardial infarct in rats and analgesia in mice.

Journal: Phytotherapy research : PTR 20080901

Title: Synthesis of l-muscone by asymmetric methylation via enol esters.

Journal: Chemistry & biodiversity 20080601

Title: [Effects of series of Muskone on heart hemodynamics and myocardial consumption of oxygen in experimental dogs].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070501

Title: Enantioselective intramolecular aldol addition/dehydration reaction of a macrocyclic diketone: synthesis of the musk odorants (R)-muscone and (R,Z)-5-muscenone.

Journal: Angewandte Chemie (International ed. in English) 20070101

Title: [Study on therapeutic effects of series of muskone on myocardial infarction canines].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001

Title: [Study on comparative pharmacology of series of Muskone].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801

Title: Normal-phase chiral liquid chromatography-mass spectrometry of non-UV-active compounds: applications for pharmaceutically relevant racemates.

Journal: Journal of chromatography. A 20060707

Title: [Determination of muscone in Xingnaojing injection by gas chromatography with solid phase microextraction].

Journal: Se pu = Chinese journal of chromatography 20050901

Title: CpRu(PN) complex-catalyzed isomerization of allylic alcohols and its application to the asymmetric synthesis of muscone.

Journal: Journal of the American Chemical Society 20050504

Title: Ti-crossed-Claisen condensation between carboxylic esters and acid chlorides or acids: a highly selective and general method for the preparation of various beta-keto esters.

Journal: Journal of the American Chemical Society 20050309

Title: [Study of diffusion of muscone in different inclusion complexes and liposome through mouse (correction of rat) skin in vitro].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050201

Title: Characterization of allegedly musk-containing medicinal products in Taiwan.

Journal: Journal of forensic sciences 20041101

Title: [An experimental study on distribution of musk into the brain through blood brain barrier].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20040701

Title: Solid-phase extraction of L-muscone from aqueous samples with Amberlite XAD-4 for gas chromatographic assay.

Journal: Archives of pharmacal research 20040501

Title: Psychological effects of musky compounds: comparison of androstadienone with androstenol and muscone.

Journal: Hormones and behavior 20021101

Title: Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells.

Journal: Archives of environmental contamination and toxicology 20021001

Title: Synthesis of (R)- and (S)- muscone.

Journal: Bioscience, biotechnology, and biochemistry 20020601

Title: Solid phase synthesis of complex natural products and libraries thereof.

Journal: Biopolymers 20010101

Title: Du Y, et al. Muscone improves cardiac function in mice after myocardial infarction by alleviating cardiac macrophage-mediated chronic inflammation through inhibition of NF-κB and NLRP3 inflammasome. Am J Transl Res. 2018 Dec 15;10(12):4235-4246.

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