Home Other Building Blocks 5411-12-1
5411-12-1,MFCD00022336
Catalog No.:AA003OOZ

5411-12-1 | CHALCONE ALPHA,BETA-EPOXIDE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
>98.0%(GC)
in stock  
$30.00   $21.00
- +
5g
>98.0%(GC)
in stock  
$91.00   $64.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003OOZ
Chemical Name:
CHALCONE ALPHA,BETA-EPOXIDE
CAS Number:
5411-12-1
Molecular Formula:
C15H12O2
Molecular Weight:
224.2546
MDL Number:
MFCD00022336
SMILES:
O=C(C1OC1c1ccccc1)c1ccccc1
Properties
Properties
 
Form:
Solid  
MP:
88-90℃  

Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
2  
XLogP3:
2.8  

Downstream Synthesis Route

[1]Yadav;Kapoor[Tetrahedron,1996,vol.52,#10,p.3659-3668]

[2]Yadav;Kapoor[Tetrahedron,1996,vol.52,#10,p.3659-3668]

[3]Locationinpatent:experimentalpartFraile,JoséM.;García,Nuria;Herrerías,ClaraI.;Mayoral,JoséA.[CatalysisToday,2011,vol.173,#1,p.15-20]

[4]Wielpuetz,Thomas;Sottmann,Thomas;Strey,Reinhard;Schmidt,Friederike;Berkessel,Albrecht[Chemistry-AEuropeanJournal,2006,vol.12,#29,p.7565-7575]

[5]Lewinski,Janusz;Ochal,Zbigniew;Bojarski,Emil;Tratkiewicz,Ewa;Justyniak,Iwona;Lipkowski,Janusz[AngewandteChemie-InternationalEdition,2003,vol.42,#38,p.4643-4646]

[6]Khosravi,Kaveh;Naserifar,Shirin[JournaloftheIranianChemicalSociety,2017,vol.14,#2,p.323-328]

[7]Khosravi,Kaveh;Naserifar,Shirin;Mahmoudi,Boshra[JournaloftheChineseChemicalSociety,2017,vol.64,#6,p.683-689]

[8]Yang,Dan;Yip,Yiu-Chung;Tang,Man-Wai;Wong,Man-Kin;Cheung,Kung-Kai[JournalofOrganicChemistry,1998,vol.63,#26,p.9888-9894]

[9]Cui,Lei;Furuhashi,Sohei;Tachikawa,Yuma;Tada,Norihiro;Miura,Tsuyoshi;Itoh,Akichika[TetrahedronLetters,2013,vol.54,#2,p.162-165]

[10]Jakka,Kavitha;Liu,Jinyun;Zhao,Cong-Gui[TetrahedronLetters,2007,vol.48,#8,p.1395-1398]

[11]Choudary;LakshmiKantam;Bharathi;VenkatReddy[Synlett,1998,#11,p.1203-1204]

[12]Sharifi,Ali;Bolourtchian,Mohammad;Mohsenzadeh,Farshid[JournalofChemicalResearch-PartS,1998,#10,p.668-669]

[13]Wu,Yufeng;Zhou,Guangli;Meng,Qingwei;Tang,Xiaofei;Liu,Guangzhi;Yin,Hang;Zhao,Jingnan;Yang,Fan;Yu,Zongyi;Luo,Yi[JournalofOrganicChemistry,2018,vol.83,#21,p.13051-13062]

[14]Peng,Yanqing;Cai,Yueqin;Song,Gonghua;Chen,Jing[Synlett,2005,#14,p.2147-2150]

[15]Okamoto,Sentaro;Takano,Kouichi;Ishikawa,Tomohiro;Ishigami,Satoshi;Tsuhako,Akiko[TetrahedronLetters,2006,vol.47,#46,p.8055-8058]

[16]Yang,SeungGak;Hwang,JePil;Park,MinYoung;Lee,Kieseung;Kim,YongHae[Tetrahedron,2007,vol.63,#24,p.5184-5188]

[17]Shi,Min;Itoh,Nobuhiro;Masaki,Yukio[JournalofChemicalResearch,Miniprint,1995,#8,p.1818-1827]

[18]Locationinpatent:experimentalpartZilbeyaz,Kani;Kilic,Hamdullah;Sisecioglu,Melda;Ozdemir,Hasan;Guengoer,AzizeAlayli[TetrahedronAsymmetry,2012,vol.23,#8,p.594-601]

[19]Oae,Shigeru;Takata,Toshikazu[TetrahedronLetters,1980,vol.21,p.3689-3692]

[20]Mandal;Khanna;Iqbal[TetrahedronLetters,1996,vol.37,#21,p.3769-3772]

[21]Bhat;Puri;Qurishi;Dhar;Qazi[SyntheticCommunications,2005,vol.35,#8,p.1135-1142]

[22]Yamaguchi,Kazuya;Mori,Kohsuke;Mizugaki,Tomoo;Ebitani,Kohki;Kaneda,Kiyotomi[JournalofOrganicChemistry,2000,vol.65,#21,p.6897-6903]

[23]Hamamoto,Hiromi;Kudoh,Masahiro;Takahashi,Hideyo;Ikegami,Shiro[OrganicLetters,2006,vol.8,#18,p.4015-4018]

[24]Das,BhaskarC;Iqbal,Javed[TetrahedronLetters,1997,vol.38,#7,p.1235-1238]

[25]Andrus,MerrittB.;Poehlein,BenjaminW.[TetrahedronLetters,2000,vol.41,#7,p.1013-1014]

[26]Sakurai,Hidehiro;Vinsen,YutaUetake[BulletinoftheChemicalSocietyofJapan,2020,vol.93,#2,p.299-301]

[27]Schuetz,StevenA.;Bowman,ElizabethA.;Silvernail,CarterM.;Day,VictorW.;Belot,JohnA.[JournalofOrganometallicChemistry,2005,vol.690,#4,p.1011-1017]

[28]Nicolas,Cyril;Lacour,Jerome[OrganicLetters,2006,vol.8,#19,p.4343-4346]

[29]Dehmlow,EckehardV.;Sauerbier,Christiane[LiebigsAnnalenderChemie,1989,p.181-186]

[30]Vieira,LucasC.C.;Matsuo,BiancaT.;Martelli,LorenaS.R.;Gall,Mayara;Paixão,MarcioW.;Corrêa,ArleneG.[OrganicandBiomolecularChemistry,2017,vol.15,#29,p.6098-6103]

[31]Hu,Ying;Harada,Akira;Takahashi,Shigetoshi[SyntheticCommunications,1988,vol.18,#4,p.1607-1610]

[32]Yadav,VeejendraK.;Kapoor,KamalK.[TetrahedronLetters,1994,vol.35,#50,p.9481-9484]

[33]Mazaleyrat,J.P.[TetrahedronLetters,1983,vol.24,#12,p.1243-1246]

[34]Annapoorna;PrasadRao;Sethuram[IndianJournalofChemistry,SectionA:Inorganic,Physical,TheoreticalandAnalytical,2001,vol.40,#3,p.283-287]

[35]Park,MinYoung;Yang,SeungGak;Kim,YongHae[HeteroatomChemistry,2002,vol.13,#5,p.431-436]

[36]Bernini,Roberta;Mincione,Enrico;Coratti,Antonietta;Fabrizi,Giancarlo;Battistuzzi,Gianfranco[Tetrahedron,2004,vol.60,#4,p.967-971]

[37]Bortolini,Olga;DeNino,Antonio;Fogagnolo,Marco;Fantin,Giancarlo;Mariuolo,Loredana;Tocci,Amedeo[ChemistryLetters,2007,vol.36,#3,p.472-473]

[38]Liu,Ye;Zhang,Hong-Jiao;Cai,Yue-Qin;Wu,Hai-Hong;Liu,Xiu-Li;Lu,Yong[ChemistryLetters,2007,vol.36,#7,p.848-849]

[39]CurrentPatentAssignee:LICAPHARMACEUTICALS-US5985935,1999,A

[40]Cheng,Chi-Yuan;Yuan,Cheng-Hui;Cheng,Sy-Chyi;Huang,Min-Zong;Chang,Hui-Chiu;Cheng,Tien-Lu;Yeh,Chen-Sheng;Shiea,Jentaie[AnalyticalChemistry,2008,vol.80,#20,p.7699-7705]

[41]Locationinpatent:schemeortableNagano,Masanobu;Doi,Mitsunobu;Kurihara,Masaaki;Suemune,Hiroshi;Tanaka,Masakazu[OrganicLetters,2010,vol.12,#15,p.3564-3566]

[42]Kubisiak,Marcin;Zelga,Karolina;Justyniak,Iwona;Tratkiewicz,Ewa;Pietrzak,Tomasz;Keeri,AbdulR.;Ochal,Zbigniew;Hartenstein,Larissa;Roesky,PeterW.;Lewinski,Janusz[Organometallics,2013,vol.32,#19,p.5263-5265]

[43]Kulkarni,NaveenV.;Das,Animesh;Ridlen,ShawnG.;Maxfield,Erin;Adiraju,VenkataA.K.;Yousufuddin,Muhammed;Dias,H.V.Rasika[DaltonTransactions,2016,vol.45,#11,p.4896-4906]

[1]Locationinpatent:experimentalpartLi,Ji-Tai;Xu,Xiao-Ya;Yin,Ying[LettersinOrganicChemistry,2011,vol.8,#3,p.198-201]

[1]OrganicLetters,2013,vol.15,p.4138-4141

[1]Wang,Heng;Ren,Shaobo;Zhang,Jian;Zhang,Wei;Liu,Yunkui[JournalofOrganicChemistry,2015,vol.80,#13,p.6856-6863]

[2]CurrentPatentAssignee:ZHEJIANGUNIVERSITYOFTECHNOLOGY-CN104926628,2016,BLocationinpatent:Paragraph0025-0028

[3]Ruan,Libo;Shi,Min;Li,Nian;Ding,Xu;Yang,Fan;Tang,Jie[OrganicLetters,2014,vol.16,#3,p.733-735]

[4]Ruan,Libo;Shi,Min;Li,Nian;Ding,Xu;Yang,Fan;Tang,Jie[OrganicLetters,2014,vol.16,#3,p.733-735]

[5]Ruan,Libo;Shi,Min;Li,Nian;Ding,Xu;Yang,Fan;Tang,Jie[OrganicLetters,2014,vol.16,#3,p.733-735]

[6]Song,Tao;Zhou,Xin;Wang,Xiaoxue;Xiao,Jianliang;Yang,Yong[GreenChemistry,2021,vol.23,#5,p.1955-1959]

[1]Ruan,Libo;Shi,Min;Li,Nian;Ding,Xu;Yang,Fan;Tang,Jie[OrganicLetters,2014,vol.16,#3,p.733-735]

[2]Ruan,Libo;Shi,Min;Li,Nian;Ding,Xu;Yang,Fan;Tang,Jie[OrganicLetters,2014,vol.16,#3,p.733-735]

[3]Ruan,Libo;Shi,Min;Li,Nian;Ding,Xu;Yang,Fan;Tang,Jie[OrganicLetters,2014,vol.16,#3,p.733-735]

Literature

Title: Uses of 2-ethoxy-4(3H) quinazolinone in synthesis of quinazoline and quinazolinone derivatives of antimicrobial activity: the solvent effect.

Journal: Global journal of health science 20120101

Title: Trans-Chalcone prevents VEGF expression and retinal neovascularization in the ischemic retina.

Journal: Experimental eye research 20111001

Title: Cell cycle arrest and apoptosis induction by an anticancer chalcone epoxide.

Journal: Archiv der Pharmazie 20100801

Title: Chalcone epoxide intermediates in the syntheses of lignin-related phenylcoumarans.

Journal: Acta crystallographica. Section C, Crystal structure communications 20061001

Title: The atmospheric pressure Meerwein reaction.

Journal: Journal of mass spectrometry : JMS 20060401

Title: C(alpha)-tetrasubstituted amino acid based peptides in asymmetric catalysis.

Journal: Biopolymers 20060101

Title: Highly enantioselective epoxidation of 2,4-diarylenones by using dimeric cinchona phase-transfer catalysts: enhancement of enantioselectivity by surfactants.

Journal: Angewandte Chemie (International ed. in English) 20050218

Title: Chiral amplification by polypeptides and its relevance to prebiotic catalysis.

Journal: Chemical communications (Cambridge, England) 20040921

Title: Excision of transposable elements from the chalcone isomerase and dihydroflavonol 4-reductase genes may contribute to the variegation of the yellow-flowered carnation (Dianthus caryophyllus).

Journal: Plant & cell physiology 20020501

Title: Influence of modulators of epoxide metabolism on the cytotoxicity of trans-anethole in freshly isolated rat hepatocytes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19920601

Title: Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds.

Journal: Chemico-biological interactions 19870101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:5411-12-1 Molecular Formula|5411-12-1 MDL|5411-12-1 SMILES|5411-12-1 CHALCONE ALPHA,BETA-EPOXIDE