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545-55-1,MFCD00081201
Catalog No.:AA01CCLA

545-55-1 | Aziridine, 1,1',1''-phosphinylidynetris-

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1g
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$3,643.00   $2,550.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA01CCLA
Chemical Name:
Aziridine, 1,1',1''-phosphinylidynetris-
CAS Number:
545-55-1
Molecular Formula:
C6H12N3OP
Molecular Weight:
173.1527
MDL Number:
MFCD00081201
SMILES:
O=P(N1CC1)(N1CC1)N1CC1
Properties
Computed Properties
 
Complexity:
194  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
-0.6  

Literature

Title: Copper depletion inhibits CoCl2-induced aggressive phenotype of MCF-7 cells via downregulation of HIF-1 and inhibition of Snail/Twist-mediated epithelial-mesenchymal transition.

Journal: Scientific reports 20150101

Title: Mechanisms and kinetics of thiotepa and tepa hydrolysis: DFT study.

Journal: Journal of molecular modeling 20120801

Title: [Simultaneous determination of six organophosphorous flame retardants in textiles by gas chromatography-tandem mass spectrometry combined with microwave assisted extraction].

Journal: Se pu = Chinese journal of chromatography 20110801

Title: Role for copper in the cellular and regulatory effects of heme-hemopexin.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090601

Title: Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.

Journal: British journal of clinical pharmacology 20090101

Title: Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.

Journal: Therapeutic drug monitoring 20051201

Title: Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N'-triethylenethiophosphoramide (thiotepa) and N,N',N'-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20040301

Title: Combined-modality treatment of leptomeningeal gliomatosis.

Journal: Neurosurgery 20030201

Title: Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy.

Journal: Bone marrow transplantation 20021101

Title: Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.

Journal: Cancer chemotherapy and pharmacology 20020601

Title: Urinary excretion of thioTEPA and its metabolites in patients treated with high-dose cyclophosphamide, thioTEPA and carboplatin.

Journal: Anti-cancer drugs 20010701

Title: Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy.

Journal: British journal of clinical pharmacology 20010101

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Tags:545-55-1 Molecular Formula|545-55-1 MDL|545-55-1 SMILES|545-55-1 Aziridine, 1,1',1''-phosphinylidynetris-