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5471-51-2,MFCD00002394
Catalog No.:AA003K17

5471-51-2 | 4-(4-Hydroxyphenyl)butan-2-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25g
98%
in stock  
$7.00   $5.00
- +
100g
98%
in stock  
$19.00   $14.00
- +
500g
98%
in stock  
$62.00   $43.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003K17
Chemical Name:
4-(4-Hydroxyphenyl)butan-2-one
CAS Number:
5471-51-2
Molecular Formula:
C10H12O2
Molecular Weight:
164.2011
MDL Number:
MFCD00002394
SMILES:
CC(=O)CCc1ccc(cc1)O
NSC Number:
26515
FEMA Number:
2588
Properties
Properties
 
BP:
292.2°C at 760 mmHg  
Form:
Solid  
MP:
81-85 °C(lit.)  
Refractive Index:
1.5250 (estimate)  
Solubility:
95% ethanol: soluble50mg/mL, clear to slightly hazy, colorless to faint yellow or tan  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
146  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
1.5  

Literature

Title: Tyrosinase-Catalyzed Oxidation of the Leukoderma-Inducing Agent Raspberry Ketone Produces (E)-4-(3-Oxo-1-butenyl)-1,2-benzoquinone: Implications for Melanocyte Toxicity.

Journal: Chemical research in toxicology 20170320

Title: Rhododenol and raspberry ketone impair the normal proliferation of melanocytes through reactive oxygen species-dependent activation of GADD45.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20160401

Title: Raspberry ketone protects rats fed high-fat diets against nonalcoholic steatohepatitis.

Journal: Journal of medicinal food 20120501

Title: Furostanol saponins from the rhizomes of Dioscorea japonica and their effects on NGF induction.

Journal: Bioorganic & medicinal chemistry letters 20110401

Title: The mouse eugenol odorant receptor: structural and functional plasticity of a broadly tuned odorant binding pocket.

Journal: Biochemistry 20110208

Title: Evaluation of in vitro and in vivo depigmenting activity of raspberry ketone from Rheum officinale.

Journal: International journal of molecular sciences 20110101

Title: Purification and biological evaluation of the metabolites produced by Streptomyces sp. TK-VL_333.

Journal: Research in microbiology 20100601

Title: Dietary exposure to flavouring substances: from screening methods to detailed assessments using food consumption data collected with EPIC-Soft software.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100401

Title: Effect of essential oils, such as raspberry ketone and its derivatives, on antiandrogenic activity based on in vitro reporter gene assay.

Journal: Bioorganic & medicinal chemistry letters 20100401

Title: Recent advances in methyl eugenol and cue-lure technologies for fruit fly detection, monitoring, and control in Hawaii.

Journal: Vitamins and hormones 20100101

Title: Evaluation of skin diseases and disorders in photographers.

Journal: Indian journal of occupational and environmental medicine 20090801

Title: Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20080801

Title: Phenols from the roots of Rheum palmatum attenuate chemotaxis in rat hepatic stellate cells.

Journal: Planta medica 20080801

Title: Characterization of headspace aroma compounds of freshly brewed arabica coffees and studies on a characteristic aroma compound of Ethiopian coffee.

Journal: Journal of food science 20080601

Title: Analysis of the headspace volatiles of freshly brewed arabica coffee using solid-phase microextraction.

Journal: Journal of food science 20070901

Title: Microbial production of 4-hydroxybenzylidene acetone, the direct precursor of raspberry ketone.

Journal: Letters in applied microbiology 20070701

Title: Biotransformation of raspberry ketone and zingerone by cultured cells of Phytolacca americana.

Journal: Phytochemistry 20070201

Title: Aroma production by tissue cultures.

Journal: Journal of agricultural and food chemistry 20060222

Title: Effect of high hydrostatic pressure on the barrier properties of polyamide-6 films.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20050801

Title: Anti-obese action of raspberry ketone.

Journal: Life sciences 20050527

Title: Synomone or kairomone?--Bulbophyllum apertum flower releases raspberry ketone to attract Bactrocera fruit flies.

Journal: Journal of chemical ecology 20050301

Title: Aroma extract dilution analysis of cv. Meeker (Rubus idaeus L.) red raspberries from Oregon and Washington.

Journal: Journal of agricultural and food chemistry 20040811

Title: Betuligenol derivative with growth inhibition and antifeedant activity.

Journal: Bioorganic & medicinal chemistry letters 20040405

Title: Raspberry ketone from submerged cultured cells of the basidiomycete Nidula niveo-tomentosa.

Journal: Biotechnology progress 20010101

Title: Park KS. Raspberry ketone, a naturally occurring phenolic compound, inhibits adipogenic and lipogenic gene expression in 3T3-L1 adipocytes. Pharm Biol. 2015 Jun;53(6):870-5.

Title: Wang L, et al. Raspberry ketone protects rats fed high-fat diets against nonalcoholic steatohepatitis. J Med Food. 2012 May;15(5):495-503.

Title: Khan V, et al. Raspberry ketone protects against isoproterenol-induced myocardial infarction in rats. Life Sci. 2018 Feb 1;194:205-212.

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