Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasis.
Journal: European journal of pharmacology 20120115
Title: MAPK phosphatase-1 contributes to trichostatin A inhibition of cyclooxygenase-2 expression in human umbilical vascular endothelial cells exposed to lipopolysaccharide.
Journal: Biochimica et biophysica acta 20111201
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: Chiral sulfoxides as metabolites of 2-thioimidazole-based p38α mitogen-activated protein kinase inhibitors: enantioselective synthesis and biological evaluation.
Journal: Journal of medicinal chemistry 20110512
Title: Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle.
Journal: European journal of pharmacology 20100610
Title: Trisubstituted purines are useful tools for developing potent plant mitogen-activated protein kinase inhibitors.
Journal: Bioscience, biotechnology, and biochemistry 20100101
Title: Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.
Journal: British journal of haematology 20090501
Title: Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region.
Journal: Journal of medicinal chemistry 20080724
Title: [Redox-dependent regulation of apoptosis as a function of intracellular reactive oxygen species in oxidative stress].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20080601
Title: Role of recombinant mitogen-activated protein kinases JNK and p38 in the regulation of apoptosis in blood mononuclear cells under conditions of oxidative stress in vitro.
Journal: Bulletin of experimental biology and medicine 20080501
Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218
Title: Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070601
Title: In vitro metabolite identification of ML3403, a 4-pyridinylimidazole-type p38 MAP kinase inhibitor by LC-Qq-TOF-MS and LC-SPE-cryo-NMR/MS.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20070301
Title: The cancer chemotherapy drug etoposide (VP-16) induces proinflammatory cytokine production and sickness behavior-like symptoms in a mouse model of cancer chemotherapy-related symptoms.
Journal: Biological research for nursing 20061001
Title: Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.
Journal: Journal of medicinal chemistry 20030717
