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55134-13-9,MFCD00133653
Catalog No.:AA00DA2Z

55134-13-9 | NARASIN

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5mg
≥97%
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25mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00DA2Z
Chemical Name:
NARASIN
CAS Number:
55134-13-9
Molecular Formula:
C43H72O11
Molecular Weight:
765.0252
MDL Number:
MFCD00133653
SMILES:
CC[C@H]([C@H]1O[C@]2(C=C[C@H]([C@@]3(O2)CC[C@@](O3)(C)[C@H]2CC[C@]([C@@H](O2)C)(O)CC)O)[C@@H](C[C@@H]1C)C)C(=O)[C@H]([C@H]([C@@H]([C@@H]1O[C@H]([C@H](C[C@@H]1C)C)[C@H](C(=O)O)CC)C)O)C
Properties
Properties
 
Form:
Solid  
MP:
185 - 186°C  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
1360  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
19  
Heavy Atom Count:
54  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
12  
XLogP3:
6.2  

Literature

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Novel amide polar-embedded reversed-phase column for the fast liquid chromatography-tandem mass spectrometry method to determine polyether ionophores in environmental waters.

Journal: Journal of chromatography. A 20121109

Title: Detection and quantitative analysis of 21 veterinary drugs in river water using high-pressure liquid chromatography coupled to tandem mass spectrometry.

Journal: Environmental science and pollution research international 20120901

Title: Simultaneous determination of human and veterinary antibiotics in various environmental matrices by rapid resolution liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Journal of chromatography. A 20120629

Title: Effects of a xylanase and protease, individually or in combination, and an ionophore coccidiostat on performance, nutrient utilization, and intestinal morphology in broiler chickens fed a wheat-soybean meal-based diet.

Journal: Poultry science 20120601

Title: Genetic diversity among VRE isolates from Swedish broilers with the coincidental finding of transferrable decreased susceptibility to narasin.

Journal: Journal of applied microbiology 20120401

Title: Simultaneous determination of five polyether ionophores using liquid chromatography with one-step fluorescent derivatization.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

Title: Non-soluble fibres and narasin reduce spontaneous gizzard erosion and ulceration in broiler chickens.

Journal: Avian pathology : journal of the W.V.P.A 20120101

Title: Quantification of ionophores in aged poultry litter using liquid chromatography tandem mass spectrometry.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101

Title: Evaluation of certain veterinary drug residues in food.

Journal: World Health Organization technical report series 20120101

Title: ERP grants first action status to candidate tissue residue methods for high-priority animal drugs.

Journal: Journal of AOAC International 20120101

Title: Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24.

Journal: Journal of AOAC International 20120101

Title: Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International 20120101

Title: Development and validation of an UPLC-MS/MS method for the determination of ionophoric and synthetic coccidiostats in vegetables.

Journal: Analytical and bioanalytical chemistry 20111201

Title: Uptake and translocation of metformin, ciprofloxacin and narasin in forage- and crop plants.

Journal: Chemosphere 20110901

Title: Rapid quantification of ionophores in feeds by liquid chromatography-tandem mass spectrometry.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110901

Title: Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.

Journal: Analytica chimica acta 20110826

Title: Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.

Journal: Analytica chimica acta 20110826

Title: Salinomycin induces calpain and cytochrome c-mediated neuronal cell death.

Journal: Cell death & disease 20110601

Title: Antimicrobial and heavy metal resistance in commensal enterococci isolated from pigs.

Journal: Veterinary microbiology 20110324

Title: Rapid and reliable identification of ionophore antibiotics in feeds by liquid chromatography-tandem mass spectrometry.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110301

Title: The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites.

Journal: Avian diseases 20110301

Title: Determination of ionophore coccidiostats in feeding stuffs by liquid chromatography-tandem mass spectrometry. Part II. Application to cross-contamination levels and non-targeted feed.

Journal: Journal of pharmaceutical and biomedical analysis 20110220

Title: A new approach to the analysis of nicarbazin and ionophores in eggs by HPLC/MS/MS.

Journal: Journal of AOAC International 20110101

Title: Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin.

Journal: Chemistry Central journal 20110101

Title: Narasin, a novel antiviral compound that blocks dengue virus protein expression.

Journal: Antiviral therapy 20110101

Title: [Simultaneous determination of polyether antibiotics and macrolide anthelmintics in livestock products by liquid chromatography/tandem mass spectrometry].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20110101

Title: Simultaneous determination of polyether ionophores, macrolides and lincosamides in hen eggs by liquid chromatography-electrospray ionization tandem mass spectrometry using a simple solvent extraction.

Journal: Analytica chimica acta 20101203

Title: Multi-residue method for detecting coccidiostats at carry-over level in feed by HPLC-MS/MS.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100601

Title: Direct aqueous supercritical fluid extraction coupled on-line with liquid chromatography-tandem mass spectrometry for the analysis of polyether ionophore antibiotics in water.

Journal: Journal of chromatography. A 20100514

Title: Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action.

Journal: Biochemical pharmacology 20100501

Title: Interference free detection for small molecules: probing the Mn2+-doped effect and cysteine capped effect on the ZnS nanoparticles for coccidiostats and peptide analysis in SALDI-TOF MS.

Journal: The Analyst 20100501

Title: The effect of commonly used anticoccidials and antibiotics in a subclinical necrotic enteritis model.

Journal: Avian pathology : journal of the W.V.P.A 20100201

Title: Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction.

Journal: Organic & biomolecular chemistry 20100107

Title: Veterinary pharmaceuticals and antibiotic resistance of Escherichia coli isolates in poultry litter from commercial farms and controlled feeding trials.

Journal: Poultry science 20100101

Title: Stereocontrolled synthesis of C1-C17 fragment of narasin via a free radical-based approach.

Journal: Organic letters 20100101

Title: Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC.

Journal: Journal of chromatography. A 20091113

Title: Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review.

Journal: Poultry science 20091101

Title: [Determination of 5 polyether antibiotics in chicken tissues by liquid chromatography-electrospray ionization tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20091101

Title: Determination of veterinary pharmaceuticals in poultry litter and soil by methanol extraction and liquid chromatography-tandem mass spectrometry.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090901

Title: Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms.

Journal: Poultry science 20090701

Title: Fate and antibacterial potency of anticoccidial drugs and their main abiotic degradation products.

Journal: Environmental pollution (Barking, Essex : 1987) 20090201

Title: Environmental contamination by vancomycin resistant enterococci (VRE) in Swedish broiler production.

Journal: Acta veterinaria Scandinavica 20090101

Title: Evaluation of certain veterinary drug residues in food.

Journal: World Health Organization technical report series 20090101

Title: Sensitivity of Eimeria field isolates in the United States: responses of nicarbazin-containing anticoccidials.

Journal: Poultry science 20080901

Title: Determination of ionophore coccidiostats in feedingstuffs by liquid chromatography-tandem mass spectrometry Part I. Application to targeted feed.

Journal: Journal of pharmaceutical and biomedical analysis 20080805

Title: Coccidia-induced mucogenesis promotes the onset of necrotic enteritis by supporting Clostridium perfringens growth.

Journal: Veterinary immunology and immunopathology 20080315

Title: Liquid chromatography-electrospray tandem mass spectrometric method for quantification of monensin in plasma and edible tissues of chicken used in pharmacokinetic studies: applying a total error approach.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Title: An integrated sample preparation to determine coccidiostats and emerging Fusarium-mycotoxins in various poultry tissues with LC-MS/MS.

Journal: Molecular nutrition & food research 20070501

Title: Efficacy of some anticoccidial drugs for treating coccidial enteritis of the common carp caused by Goussia carpelli (Apicomplexa: Eimeriidae).

Journal: Acta veterinaria Hungarica 20070301

Title: Occurrence of ionophore antibiotics in water and sediments of a mixed-landscape watershed.

Journal: Water research 20060701

Title: Simultaneous determination of four coccidiostats in eggs and broiler meat: validation of an LC-MS/MS method.

Journal: Food additives and contaminants 20060501

Title: Determination of monensin, narasin, and salinomycin in mineral premixes, supplements, and animal feeds by liquid chromatography and post-column derivatization: collaborative study.

Journal: Journal of AOAC International 20060101

Title: Incidence of residues of nine anticoccidials in eggs.

Journal: Food additives and contaminants 20051101

Title: Deposition and depletion of five anticoccidials in eggs.

Journal: Journal of agricultural and food chemistry 20050907

Title: Rapid analysis of trace levels of antibiotic polyether ionophores in surface water by solid-phase extraction and liquid chromatography with ion trap tandem mass spectrometric detection.

Journal: Journal of chromatography. A 20050218

Title: The residue levels of narasin in eggs of laying hens fed with unmedicated and medicated feed.

Journal: Molecular nutrition & food research 20050101

Title: Determination of the ionophoric coccidiostats narasin, monensin, lasalocid and salinomycin in eggs by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Validation of a method for the determination of narasin in the edible tissues of chickens by liquid chromatography.

Journal: Journal of AOAC International 20050101

Title: Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

Title: Prevalence of vancomycin resistant enterococci on poultry farms established after the ban of avoparcin.

Journal: Avian diseases 20041201

Title: Development of multiclass methods for drug residues in eggs: silica SPE cleanup and LC-MS/MS analysis of ionophore and macrolide residues.

Journal: Journal of agricultural and food chemistry 20041117

Title: Antimicrobial susceptibility of Swedish, Norwegian and Danish isolates of Clostridium perfringens from poultry, and distribution of tetracycline resistance genes.

Journal: Veterinary microbiology 20040419

Title: Rapid time-resolved fluoroimmunoassay for the screening of narasin and salinomycin residues in poultry and eggs.

Journal: Journal of agricultural and food chemistry 20040407

Title: Susceptibility of Clostridium perfringens strains from broiler chickens to antibiotics and anticoccidials.

Journal: Avian pathology : journal of the W.V.P.A 20040201

Title: What has happened in norway after the ban of avoparcin? Consumption of antimicrobials by poultry.

Journal: Preventive veterinary medicine 20040130

Title: Liquid chromatographic method to determine narasin in feedingstuffs and premixtures: development, validation, and interlaboratory study.

Journal: Journal of AOAC International 20040101

Title: Ionophores: their use as ruminant growth promotants and impact on food safety.

Journal: Current issues in intestinal microbiology 20030901

Title: Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001.

Journal: Avian pathology : journal of the W.V.P.A 20030801

Title: The efficacy of bacitracin methylene disalicylate when fed in combination with narasin in the management of necrotic enteritis in broiler chickens.

Journal: Poultry science 20030301

Title: A new method for in vitro detection of microbially produced mitochondrial toxins.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030101

Title: The determination of 5 anticoccidial drugs (nicarbazin, lasalocid, monensin, salinomycin and narasin) in animal livers and eggs by liquid chromatography linked with tandem mass spectrometry (LC-MS-MS).

Journal: The Analyst 20020601

Title: Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics.

Journal: Chirality 20020101

Title: Comparison of susceptibility to antimicrobials of the enterococcal species isolated from pigeons (Columba livia).

Journal: Microbial drug resistance (Larchmont, N.Y.) 20020101

Title: Efficient and sensitive screening and confirmation of residues of selected polyether ionophore antibiotics in liver and eggs by liquid chromatography-electrospray tandem mass spectrometry.

Journal: The Analyst 20011101

Title: Efficacy of diclazuril in comparison with chemical and ionophorous anticoccidials against Eimeria spp. in broiler chickens in floor pens.

Journal: Poultry science 20010401

Title: A method for measuring potency of narasin extracts using near-IR spectroscopy.

Journal: Journal of pharmaceutical and biomedical analysis 20010101

Title: Reduced incidence of Clostridium perfringens-associated lesions and improved performance in broiler chickens treated with normal intestinal bacteria from adult fowl.

Journal: Avian diseases 20010101

Title: Efficacy of narasin in the prevention of necrotic enteritis in broiler chickens.

Journal: Avian diseases 20010101

Title: LC/MS confirmation of ionophores in animal feeds.

Journal: Journal of AOAC International 20010101

Title: Ghada Bouguerra, et al. Stimulation of Eryptosis by Narasin. Cell Physiol Biochem. 2015;37(5):1807-16.

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