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552-62-5,MFCD00037979
Catalog No.:AA00D8O0

552-62-5 | 7-Methylxanthine

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50mg
≥98%
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$70.00   $49.00
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100mg
≥98%
in stock  
$132.00   $92.00
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250mg
≥98%
in stock  
$289.00   $202.00
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500mg
≥98%
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$543.00   $380.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00D8O0
Chemical Name:
7-Methylxanthine
CAS Number:
552-62-5
Molecular Formula:
C6H6N4O2
Molecular Weight:
166.1374
MDL Number:
MFCD00037979
SMILES:
O=c1[nH]c(=O)c2c([nH]1)ncn2C
NSC Number:
7861
Properties
Computed Properties
 
Complexity:
242  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
-0.9  

Literature

Title: Role of carotenoids in light-harvesting processes in an antenna protein from the chromophyte Xanthonema debile.

Journal: The journal of physical chemistry. B 20120802

Title: Effects of 7-methylxanthine on form-deprivation myopia in pigmented rabbits.

Journal: International journal of ophthalmology 20120101

Title: Effects of 7-methylxanthine on the sclera in form deprivation myopia in guinea pigs.

Journal: Acta ophthalmologica 20110601

Title: Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source.

Journal: Microbiology (Reading, England) 20110201

Title: Distribution, biosynthesis and catabolism of methylxanthines in plants.

Journal: Handbook of experimental pharmacology 20110101

Title: Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds.

Journal: BMC genomics 20110101

Title: Adenosine receptor protein changes in guinea pigs with form deprivation myopia.

Journal: Acta ophthalmologica 20101101

Title: Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine.

Journal: Bioorganic & medicinal chemistry 20100915

Title: Carotenoids in clams, Ruditapes philippinarum and Meretrix petechialis.

Journal: Journal of agricultural and food chemistry 20100512

Title: Altered expression of the caffeine synthase gene in a naturally caffeine-free mutant of Coffea arabica.

Journal: Genetics and molecular biology 20090101

Title: Systemic 7-methylxanthine in retarding axial eye growth and myopia progression: a 36-month pilot study.

Journal: Journal of ocular biology, diseases, and informatics 20081201

Title: Non-standard base pairing and stacked structures in methyl xanthine clusters.

Journal: Physical chemistry chemical physics : PCCP 20080521

Title: Distribution of adenosine receptors in human sclera fibroblasts.

Journal: Molecular vision 20080101

Title: Degradation kinetics of caffeine and related methylxanthines by induced cells of Pseudomonas sp.

Journal: Current microbiology 20070701

Title: Methylated purines in urinary stones.

Journal: Clinical chemistry 20050801

Title: Simultaneous determination of 16 purine derivatives in urinary calculi by gradient reversed-phase high-performance liquid chromatography with UV detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525

Title: Coffee and tomato share common gene repertoires as revealed by deep sequencing of seed and cherry transcripts.

Journal: TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20050101

Title: Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20041011

Title: Separation, pre-concentration, and HPLC analysis of methylxanthines in urine samples.

Journal: Journal of separation science 20041001

Title: Catabolism of caffeine in plants and microorganisms.

Journal: Frontiers in bioscience : a journal and virtual library 20040501

Title: Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants.

Journal: Plant physiology 20030501

Title: Isolation of a new dual-functional caffeine synthase gene encoding an enzyme for the conversion of 7-methylxanthine to caffeine from coffee (Coffea arabica L.).

Journal: FEBS letters 20030116

Title: Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee.

Journal: Journal of pharmaceutical and biomedical analysis 20021015

Title: Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2.

Journal: Biochemical pharmacology 20020615

Title: [Research on the separation of caffeine and its nine analogues by micellar electrokinetic capillary chromatography].

Journal: Se pu = Chinese journal of chromatography 20020501

Title: Group I aptazymes as genetic regulatory switches.

Journal: BMC biotechnology 20020101

Title: Use of novel solid-phase extraction sorbent materials for high-performance liquid chromatography quantitation of caffeine metabolism products methylxanthines and methyluric acids in samples of biological origin.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010815

Title: Oral pentoxifylline inhibits release of tumor necrosis factor-alpha from human peripheral blood monocytes : a potential treatment for aseptic loosening of total joint components.

Journal: The Journal of bone and joint surgery. American volume 20010701

Title: 7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties.

Journal: The Journal of biological chemistry 20010316

Title: Determination of urinary methylated purine pattern by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010210

Title: Caffeine metabolism before and after liver transplantation.

Journal: International journal of clinical pharmacology and therapeutics 20010201

Title: Caffeine metabolism in a group of 67 patients with primary biliary cirrhosis.

Journal: International journal of clinical pharmacology and therapeutics 20010101

Title: Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism.

Journal: British journal of clinical pharmacology 19990301

Title: Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors.

Journal: Journal of medicinal chemistry 19931029

Title: Caubet MS, et al. Determination of urinary 13C-caffeine metabolites by liquid chromatography-mass spectrometry: the use of metabolic ratios to assess CYP1A2 activity. J Pharm Biomed Anal. 2004 Feb 4;34(2):379-89.

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