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554-92-7,MFCD00057999
Catalog No.:AA00I9T1

554-92-7 | Trimethobenzamide hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
99%(HPLC)
in stock  
$43.00   $30.00
- +
100mg
99%(HPLC)
in stock  
$107.00   $75.00
- +
1g
>98.0%(T)(HPLC)
in stock  
$135.00   $95.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I9T1
Chemical Name:
Trimethobenzamide hydrochloride
CAS Number:
554-92-7
Molecular Formula:
C21H29ClN2O5
Molecular Weight:
424.9184
MDL Number:
MFCD00057999
SMILES:
COc1cc(cc(c1OC)OC)C(=O)NCc1ccc(cc1)OCCN(C)C.Cl
Properties
Computed Properties
 
Complexity:
440  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  

Literature

Title: Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.

Journal: Toxicology letters 20150105

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Growth failure, tardive dyskinesia, megacolon development, and hepatic damage in neonatal rats following exposure to trimethobenzamide in utero.

Journal: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20110901

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Standardizing emergency department-based migraine research: an analysis of commonly used clinical trial outcome measures.

Journal: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20100101

Title: FDA halts sales of some anti-vomiting suppositories...and are cough medications effective in children?

Journal: Child health alert 20070501

Title: Effects of rivastigmine on cognitive function in patients with traumatic brain injury.

Journal: Neurology 20060912

Title: A clinical trial of trimethobenzamide/diphenhydramine versus sumatriptan for acute migraines.

Journal: Headache 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: 10 questions about using apomorphine for Parkinson disease.

Journal: The neurologist 20050501

Title: 'Seeing catatonia'.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20050101

Title: Trimethobenzamide in elderly patients.

Journal: Mayo Clinic proceedings 20040601

Title: Intranasal apomorphine rescue therapy for parkinsonian 'off' periods.

Journal: Clinical neuropharmacology 19960601

Title: Prune belly syndrome and heart defect in one of monozygotic twins, following exposure to Tigan and Bendectin.

Journal: Acta geneticae medicae et gemellologiae 19850101

Title: Trimethobenzamide HCl in the treatment of nausea and vomiting associated with antineoplastic chemotherapy.

Journal: Journal of clinical pharmacology 19800101

Title: [ANTIEMETIC ACTION OF METOCLOPRAMIDE WITH RESPECT TO APOMORPHINE AND HYDERGINE].

Journal: Comptes rendus des seances de la Societe de biologie et de ses filiales 19640101

Title: Smith HS, et al. Dopamine receptor antagonists. Ann Palliat Med. 2012 Jul;1(2):137-42.

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SDS
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