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5545-17-5,MFCD00152053
Catalog No.:AA00DE2Y

5545-17-5 | N,N'-Diacetyl-l-cystine

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Purity
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100mg
97%
in stock  
$51.00   $36.00
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250mg
97%
in stock  
$87.00   $61.00
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1g
≥90%
in stock  
$105.00   $73.00
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5g
97%
in stock  
$390.00   $273.00
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10g
95%
in stock  
$710.00   $497.00
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25g
95%
in stock  
$1,407.00   $985.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DE2Y
Chemical Name:
N,N'-Diacetyl-l-cystine
CAS Number:
5545-17-5
Molecular Formula:
C10H16N2O6S2
Molecular Weight:
324.3738
MDL Number:
MFCD00152053
SMILES:
OC(=O)[C@@H](NC(=O)C)CSSC[C@@H](C(=O)O)NC(=O)C
Properties
Properties
 
BP:
715.5°C at 760 mmHg  
Form:
Solid  
MP:
55-72°C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
354  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
9  
XLogP3:
-0.4  

Downstream Synthesis Route

[1]BiochemicalJournal,1931,vol.25,p.619

[1]JournalofBiologicalChemistry,1931,vol.94,p.244

[1]JournalofBiologicalChemistry,1931,vol.94,p.247

[1]JournalofBiologicalChemistry,1956,vol.218,p.449,450

[1]JournalofBiologicalChemistry,1931,vol.94,p.244

Literature

Title: The new oral immunomodulating drug DiNAC induces brachial artery vasodilatation at rest and during hyperemia in hypercholesterolemic subjects, likely by a nitric oxide-dependent mechanism.

Journal: Atherosclerosis 20080101

Title: N,N-diacetyl-L-cystine improves endothelial function in atherosclerotic Watanabe heritable hyperlipidaemic rabbits.

Journal: Basic & clinical pharmacology & toxicology 20070101

Title: Influence of N,N'-diacetyl-L-cystine on D-galactosamine/lipopolysaccharide induced immunological liver failure in mice.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20041001

Title: The antiatherogenic effect of DiNAC: experimental findings supporting immunomodulation as a new treatment for atherosclerosis related diseases.

Journal: Cardiovascular drug reviews 20030101

Title: Immunomodulation with DiNAC-- a new approach to the treatment of atherosclerosis?

Journal: Expert opinion on investigational drugs 20020501

Title: N,N'-diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: evidence for immunomodulatory agents as a new approach to prevent atherosclerosis.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Monitoring of the subtraction process in solid-phase representational difference analysis: characterization of a candidate drug.

Journal: Gene 20010627

Title: Wågberg M, et al. N,N'-diacetyl-L-cystine (DiNAC), the disulphide dimer of N-acetylcysteine, inhibits atherosclerosis in WHHL rabbits: evidence for immunomodulatory agents as a new approach to prevent atherosclerosis. J Pharmacol Exp Ther. 2001 Oct;299(1):76-82.

Title: Särnstrand B, et al. N,N'-Diacetyl-L-cystine-the disulfide dimer of N-acetylcysteine-is a potent modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. J Pharmacol Exp Ther. 1999 Mar;288(3):1174-84.

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SDS
Tags:5545-17-5 Molecular Formula|5545-17-5 MDL|5545-17-5 SMILES|5545-17-5 N,N'-Diacetyl-l-cystine