Title: Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.
Journal: Oncotarget 20151020
Title: F2A sequence linking MGMT(P140K) and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells.
Journal: Cancer gene therapy 20121101
Title: p53R2 is a prognostic factor of melanoma and regulates proliferation and chemosensitivity of melanoma cells.
Journal: Journal of dermatological science 20121001
Title: Chloroethylnitrosourea-induced cell death and genotoxicity: cell cycle dependence and the role of DNA double-strand breaks, HR and NHEJ.
Journal: Cell cycle (Georgetown, Tex.) 20120715
Title: Effects of chemotherapeutics on organotypic corticostriatal slice cultures identified by a panel of fluorescent and immunohistochemical markers.
Journal: Neurotoxicity research 20120701
Title: The chloroethylating anticancer drug ACNU induces FRA1 that is involved in drug resistance of glioma cells.
Journal: Biochimica et biophysica acta 20120701
Title: Safety and feasibility of convection-enhanced delivery of nimustine hydrochloride co-infused with free gadolinium for real-time monitoring in the primate brain.
Journal: Neurological research 20120701
Title: [Selected arterial infusion chemotherapy combined with target drugs for non-small cell lung cancer with multiple brain metastase].
Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20120520
Title: Nimustine hydrochloride: the first crystal structure determination of a 2-chloroethyl-N-nitrosourea hydrochloride derivative by X-ray powder diffraction and solid-state NMR.
Journal: Acta crystallographica. Section C, Crystal structure communications 20120301
Title: Phase II trial of radiotherapy after hyperbaric oxygenation with multiagent chemotherapy (procarbazine, nimustine, and vincristine) for high-grade gliomas: long-term results.
Journal: International journal of radiation oncology, biology, physics 20120201
Title: Anaplastic oligodendroglial tumors harboring 1p/19q deletion can be successfully treated without radiotherapy.
Journal: Anticancer research 20111201
Title: Local convection-enhanced delivery of chemotherapeutic agent transiently opens blood-brain barrier and improves efficacy of systemic chemotherapy in intracranial xenograft tumor model.
Journal: Cancer letters 20111101
Title: An anti-transferrin receptor antibody enhanced the growth inhibitory effects of chemotherapeutic drugs on human glioma cells.
Journal: International immunopharmacology 20111101
Title: Regression of recurrent glioblastoma infiltrating the brainstem after convection-enhanced delivery of nimustine hydrochloride.
Journal: Journal of neurosurgery. Pediatrics 20110501
Title: [Nimotuzumab in combination with chemotherapy for patients with malignant gliomas].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110301
Title: Primary malignant melanoma of the esophagus: a study of clinical features, pathology, management and prognosis.
Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110201
Title: Therapy-related myelodysplastic syndrome developed by dacarbazine, nimustine hydrochloride and vincristine sulfate (DAV) therapy for patient with malignant melanoma.
Journal: The Journal of dermatology 20110201
Title: Effectiveness of interferon-beta therapy for recurrent glioblastoma: a case report.
Journal: Tumori 20110101
Title: FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ.
Journal: PloS one 20110101
Title: [A case report of anorectal malignant melanoma showing a complete response after DTIC/ACNU/VCR therapy].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20101001
Title: Malignant melanoma of the breast: N-isopropyl-p-(123) I-iodoamphetamine single photon emission computed tomography ((123) I-IMP SPECT) is useful for the detection of metastasis.
Journal: The Journal of dermatology 20100901
Title: Effect of inhibition of the ROCK isoform on RT2 malignant glioma cells.
Journal: Anticancer research 20100901
Title: [Case of primary amelanotic malignant melanoma of the female urethra].
Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20100901
Title: DNA ligase IV is a potential molecular target in ACNU sensitivity.
Journal: Cancer science 20100801
Title: Complete remission of metastatic malignant melanoma after surgery in association with development of systemic vitiligo.
Journal: The Journal of dermatology 20100801
Title: Phase I/II trial of hyperfractionated concomitant boost proton radiotherapy for supratentorial glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20100501
Title: Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.
Journal: Oncology reports 20100501
Title: Radiation-induced glioblastoma occurring 35 years after radiation therapy for medulloblastoma: case report.
Journal: Brain tumor pathology 20100401
Title: Prognostic factors for patients with gliomatosis cerebri: retrospective analysis of 17 consecutive cases.
Journal: Neurosurgical review 20100401
Title: Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).
Journal: Gene therapy 20100301
Title: Decreasing expression of the interleukin-13 receptor IL-13Ralpha2 in treated recurrent malignant gliomas.
Journal: Neurologia medico-chirurgica 20100101
Title: Phase II study of nimustine hydrochloride (ACNU) plus paclitaxel for refractory small cell lung cancer.
Journal: Lung cancer (Amsterdam, Netherlands) 20091201
Title: Long-term survivors of glioblastoma: clinical features and molecular analysis.
Journal: Acta neurochirurgica 20091101
Title: [Metastatic malignant melanoma of the urinary bladder: a case report].
Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20091101
Title: Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin.
Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20090801
Title: Coincidence of central neurocytoma and multiple glioblastomas: a rare case report.
Journal: Journal of neuro-oncology 20090701
Title: FEN1 is overexpressed in testis, lung and brain tumors.
Journal: Anticancer research 20090701
Title: [Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090601
Title: Melanocytoma in the orbital apex.
Journal: Journal of neuro-oncology 20090301
Title: ACNU-based chemotherapy for recurrent glioma in the temozolomide era.
Journal: Journal of neuro-oncology 20090301
Title: Nimustine (ACNU) plus teniposide (VM26) in recurrent glioblastoma.
Journal: Oncology 20090101
Title: Preradiation chemotherapy with ACNU-CDDP in patients with newly diagnosed glioblastoma: a retrospective analysis.
Journal: Chemotherapy 20090101
Title: Successful treatment of neoadjuvant therapy for papillary tumor of the pineal region.
Journal: Brain tumor pathology 20090101
Title: Cervical intramedullary glioblastoma: report of a long-term survival case and a review of the literature.
Journal: Journal of UOEH 20081201
Title: Enhanced antitumor effect of combined-modality treatment using convection-enhanced delivery of hydrophilic nitrosourea with irradiation or systemic administration of temozolomide in intracranial brain tumor xenografts.
Journal: Neurological research 20081101
Title: [Combined treatment with dacarbazine, nimustine, cisplatin, and tamoxifen plus interferon-beta in a patient with advanced anorectal malignant melanoma].
Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20081101
Title: Different initial steps of apoptosis induced by two types of antineoplastic drugs.
Journal: Biochemical pharmacology 20080801
Title: Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance.
Journal: Molecular pharmacology 20080701
Title: Treatment and prognosis of malignant melanoma of the oral cavity: preoperative surgical procedure increases risk of distant metastasis.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20080701
Title: Survival following CyberKnife radiosurgery and hypofractionated radiotherapy for newly diagnosed glioblastoma multiforme.
Journal: Technology in cancer research & treatment 20080601
Title: Intrathecal chemotherapy for refractory disseminated medulloblastoma.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20080501
Title: Nitrosourea efficacy in high-grade glioma: a survival gain analysis summarizing 504 cohorts with 24193 patients.
Journal: Journal of neuro-oncology 20080501
Title: Chemotherapeutic choice of ranimustine or nimustine on the basis of regional polyamine levels in rat brain.
Journal: Methods and findings in experimental and clinical pharmacology 20080301
Title: Response to chemotherapy and tandem autologous transplantation of multiple myeloma patients and GSTP1 and TYMS polymorphisms.
Journal: Leukemia research 20080101
Title: Prospective single-arm study of 72 Gy hyperfractionated radiation therapy and combination chemotherapy for anaplastic astrocytomas.
Journal: BMC cancer 20080101
Title: Intra-axial brainstem malignant melanoma mimicking cavernous angioma--case report.
Journal: Neurologia medico-chirurgica 20080101
Title: Modes of actions of two types of anti-neoplastic drugs, dacarbazine and ACNU, to induce apoptosis.
Journal: Carcinogenesis 20071201
Title: Primary CNS lymphoma treated with combined intra-arterial ACNU and radiotherapy.
Journal: Acta neurochirurgica 20071101
Title: Phase I/II clinical trial of carbon ion radiotherapy for malignant gliomas: combined X-ray radiotherapy, chemotherapy, and carbon ion radiotherapy.
Journal: International journal of radiation oncology, biology, physics 20071001
Title: Long-term follow-up of busulfan, etoposide, and nimustine hydrochloride (ACNU) or melphalan as conditioning regimens for childhood acute leukemia and lymphoma.
Journal: International journal of hematology 20071001
Title: Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells.
Journal: Journal of neuro-oncology 20070901
Title: The combined effects of multiple chemotherapeutic agents for malignant glioma cells.
Journal: Journal of neuro-oncology 20070801
Title: Local injection of interferon beta in malignant melanoma of the esophagus as adjuvant of systemic pre- and postoperative DAV chemotherapy: case report with 7 years of long-term survival.
Journal: Gastrointestinal endoscopy 20070801
Title: Collagen gel matrix assay as an in vitro chemosensitivity test for malignant astrocytic tumors.
Journal: International journal of clinical oncology 20070401
Title: Safety and efficacy of convection-enhanced delivery of ACNU, a hydrophilic nitrosourea, in intracranial brain tumor models.
Journal: Journal of neuro-oncology 20070301
Title: Chromosome arm 1q gain associated with good response to chemotherapy in a malignant glioma. Case report.
Journal: Journal of neurosurgery 20070301
Title: Feasibility and response to 1-(4-amino-2-methyl-5-pyrimidynyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride chemotherapy with pre-treated procarbazine for elderly patients with newly diagnosed glioblastoma.
Journal: Journal of neuro-oncology 20070201
Title: Analysis of long-term survivors of glioblastoma multiforme in a single institution with aggressive local retreatment protocol.
Journal: Anticancer research 20070101
Title: Pegfilgrastim compared with filgrastim after high-dose melphalan and autologous hematopoietic peripheral blood stem cell transplantation in multiple myeloma patients.
Journal: European journal of haematology 20061101
Title: Phase II trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.
Journal: British journal of cancer 20061009
Title: Gene expression profiles of 1-(4-amino-2-methyl-5-pyrimidinyl)-methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU)-resistant C6 rat glioma cells.
Journal: Journal of neuro-oncology 20060901
Title: Phase II study of nimustine, carboplatin, vincristine, and interferon-beta with radiotherapy for glioblastoma multiforme: experience of the Kyoto Neuro-Oncology Group.
Journal: Journal of neurosurgery 20060901
Title: [Glioma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060701
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Acute myocardial infarction induced by cisplatin-based combination chemotherapy for malignant melanoma: a case report.
Journal: Journal of cardiology 20060401
Title: High-dose idarubicin, busulphan and melphalan for autologous stem cell transplantation in multiple myeloma responsive to DAV chemotherapy: comparison with a historical control.
Journal: Acta haematologica 20060101
Title: Acquisition of resistance to antitumor alkylating agent ACNU: a possible target of positron emission tomography monitoring.
Journal: Nuclear medicine and biology 20060101
Title: A randomized phase III study: comparison between intravenous and intraarterial ACNU administration in newly diagnosed primary glioblastomas.
Journal: Anticancer research 20060101
Title: Hyperfractionated radiotherapy and multi-agent chemotherapy (procarbazine, ACNU and vincristine) for high-grade gliomas: a prospective study.
Journal: Anticancer research 20060101
Title: Glioblastoma multiforme with oligodendroglial component (GBMO): favorable outcome after post-operative radiotherapy and chemotherapy with nimustine (ACNU) and teniposide (VM26).
Journal: BMC cancer 20060101
Title: Combination hepatic arterial infusion therapy is effective for ocular melanoma metastasis to the liver.
Journal: Oncology reports 20051201
Title: [Treatment for malignant glioma].
Journal: No to shinkei = Brain and nerve 20051201
Title: ACNU-cisplatin continuous infusion chemotherapy as salvage therapy for recurrent glioblastomas: phase II study.
Journal: Journal of neuro-oncology 20051101
Title: Down-regulation of O6-methylguanine-DNA methyltransferase gene expression in gliomas by platinum compounds.
Journal: Oncology reports 20051101
Title: [Standards and new developments in the chemotherapy of glioblastomas].
Journal: Deutsche medizinische Wochenschrift (1946) 20051007
Title: [Chemotherapy for brain tumor].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: Amelanotic malignant melanoma of the esophagus: report of a patient with recurrence successfully treated with chemoendocrine therapy.
Journal: International journal of clinical oncology 20050601
Title: Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
Journal: Oncology reports 20050501
Title: Local drug delivery in recurrent malignant gliomas.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050501
Title: [Resent advances in chemotherapy for malignant brain tumors].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050401
Title: Human interferon beta, nimustine hydrochloride, and radiation therapy in the treatment of newly diagnosed malignant astrocytomas.
Journal: Journal of neuro-oncology 20050301
Title: O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course.
Journal: International journal of cancer 20050210
Title: [Medulloblastoma with mandibular metastasis after complete remission of the central nervous system lesions].
Journal: No to shinkei = Brain and nerve 20050101
Title: Hypofractionated stereotactic re-irradiation: treatment option in recurrent malignant glioma.
Journal: BMC cancer 20050101
Title: The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
Journal: Anticancer research 20050101
Title: Treatment of low-grade oligodendroglial tumors without radiotherapy.
Journal: Neurology 20041228
Title: Immunohistochemical study for O6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas.
Journal: Journal of neuro-oncology 20041201
Title: [Glioblastoma multiforme of the optic nerve].
Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20041101
Title: Induction of the DNA repair gene O6-methylguanine-DNA methyltransferase by dexamethasone in glioblastomas.
Journal: Journal of neurosurgery 20041001
Title: [Study on MGMT assay and tumor individual predictable chemotherapy].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20040601
Title: Randomized controlled trial on malignant brain tumors--activities of the Japan Clinical Oncology Group-Brain Tumor Study Group.
Journal: Neurologia medico-chirurgica 20040401
Title: Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-based chemotherapy.
Journal: Neurosurgery 20040201
Title: [Role of thallium SPECT for evaluating the effect of maintenance chemotherapy against malignant gliomas].
Journal: No shinkei geka. Neurological surgery 20031201
Title: Primary malignant melanoma of the oral mucosa.
Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20031001
Title: Neuro-Oncology Working Group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901
Title: In vitro growth suppression of human glioma cells by a 16-mer oligopeptide: a potential new treatment modality for malignant glioma.
Journal: Journal of neuro-oncology 20030601
Title: [Malignant melanoma of the alimentary tract].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030501
Title: Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: an immunohistochemical analysis.
Journal: Neurological research 20030401
Title: Prospective trial of radiotherapy after hyperbaric oxygenation with chemotherapy for high-grade gliomas.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030401
Title: Regression of refractory rhabdomyosarcoma after allogeneic stem-cell transplantation.
Journal: Pediatric hematology and oncology 20030301
Title: O6-methylguanine-DNA methyltranspherase gene expression in gliomas by means of real-time quantitative RT-PCR and clinical response to nitrosoureas.
Journal: International journal of cancer 20030101
Title: Complete remission of metastatic clear cell sarcoma with DAV chemotherapy.
Journal: Clinical and experimental dermatology 20030101
Title: A phase II study of radiotherapy after hyperbaric oxygenation combined with interferon-beta and nimustine hydrochloride to treat supratentorial malignant gliomas.
Journal: Journal of neuro-oncology 20030101
Title: Anti-vascular endothelial growth factor antibody and nimustine as combined therapy: effects on tumour growth and angiogenesis in human glioblastoma xenografts.
Journal: Neuro-oncology 20030101
Title: Intra-arterial ACNU and carboplatin versus intravenous chemotherapy with cisplatin and BCNU in newly diagnosed patients with glioblastoma.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20021201
Title: Phase II study of chemotherapy with ACNU plus cisplatin followed by cranial irradiation in patients with newly diagnosed glioblastoma multiforme.
Journal: Journal of neuro-oncology 20021101
Title: Suppression of Cdc2 dephosphorylation at the tyrosine 15 residue during nitrosourea-induced G2M phase arrest in glioblastoma cell lines.
Journal: Journal of neuro-oncology 20020801
Title: Effects of combination chemotherapy with biscoclaurine-derived alkaloid (Cepharanthine) and nimustine hydrochloride on malignant glioma cell lines.
Journal: Journal of neuro-oncology 20020101
Title: Comparative cytotoxicity of carmustine (BCNU), nimustine (ACNU) and elmustine (HeCNU) after depletion of O6-alkylguanine-DNA alkyltransferase (O6-AGT).
Journal: Anticancer research 20020101
Title: Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
Journal: European journal of haematology 20010701
Title: Radiotherapy combined with nimustine hydrochloride and etoposide for malignant gliomas: results of a pilot study.
Journal: Japanese journal of clinical oncology 20010601
Title: Pharmacokinetics of nimustine, cytosine arabinoside, and methotrexate in cerebrospinal fluid during cerebrospinal fluid perfusion chemotherapy.
Journal: Biological & pharmaceutical bulletin 20010401
Title: Efficacy of single-bolus vs. frequent low-dose treatment with nitrosourea in experimental gliomas.
Journal: Anticancer research 20010101
Title: Intratumoral microinfusion of nimustine (ACNU) for recurrent glioma.
Journal: Brain tumor pathology 20010101
Title: Primary malignant melanoma of the esophagus treated by esophagectomy and systemic chemotherapy.
Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20010101
Title: Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase.
Journal: Carcinogenesis 20001001
Title: Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme.
Journal: Cancer chemotherapy and pharmacology 20000101
Title: Transient induction of the MRP/GS-X pump and gamma-glutamylcysteine synthetase by 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3- nitrosourea in human glioma cells.
Journal: Cancer research 19971201
Title: Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring.
Journal: Cancer causes & control : CCC 19970501
Title: Determinants of drug response in a cisplatin-resistant human lung cancer cell line.
Journal: Japanese journal of cancer research : Gann 19900501
Title: [The combination chemotherapy of vincristine, methotrexate, ACNU, and adriamycin for anaplastic carcinoma of the lung].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 19820701
Title: Tomicic MT, et al. Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM. Oncotarget. 2015 Oct 20;6(32):33755-68.
Title: Kondo N, et al. FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ. PLoS One. 2011 May 9;6(5):e19659.
Title: Mineura K, et al. DNA lability induced by nimustine and ramustine in rat glioma cells. J Neurol Neurosurg Psychiatry. 1988 Nov;51(11):1391-4.
