Home Other Building Blocks 557-24-4
557-24-4,MFCD00082354
Catalog No.:AA00351I

557-24-4 | Maleamic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$13.00   $9.00
- +
5g
98%
in stock  
$37.00   $26.00
- +
25g
>98.0%(T)(HPLC)
in stock  
$58.00   $40.00
- +
500g
>98.0%(T)(HPLC)
in stock  
$444.00   $311.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00351I
Chemical Name:
Maleamic acid
CAS Number:
557-24-4
Molecular Formula:
C4H5NO3
Molecular Weight:
115.0874
MDL Number:
MFCD00082354
SMILES:
NC(=O)/C=C\C(=O)O
NSC Number:
3246
Properties
Properties
 
BP:
215.33°C (rough estimate)  
Form:
Solid  
MP:
158-161 °C(lit.)  
Refractive Index:
1.4170 (estimate)  
Storage:
Light sensitive;Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
138  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
-1  

Upstream Synthesis Route

[1]AdvancedSynthesisandCatalysis,2018,vol.360,#18,p.3553-3562

[2]DRP/DRBPOrg.Chem.,

[3]DRP/DRBPOrg.Chem.,

[4]DRP/DRBPOrg.Chem.,

[5]Patent:DE945987,1956,,

[6]JustusLiebigsAnnalenderChemie,1890,vol.259,p.141

[7]IstanbulUniversitesiFenFakultesiMecmuasi,SeriA:Matematik-Fizik-Kimya,1948,vol.13,p.127

[8]Chem.Abstr.,1948,p.8190

[9]DRP/DRBPOrg.Chem.,

[10]JournalofOrganicChemistry,1992,vol.57,#24,p.6684-6686

[11]Patent:US4600775,1986,A,

[12]Patent:US4789742,1988,A,

[13]Patent:JP2017/66132,2017,A,.Locationinpatent:Paragraph0019;0021;0024-0026

[1]Patent:US4917826,1990,A,

[1]Patent:US2003/60441,2003,A1,

[2]Patent:US4980482,1990,A,

[1]Patent:US5475021,1995,A,

[1]Patent:EP758314,1999,B1,

Downstream Synthesis Route
186581-53-3    557-24-4   
3-carbamoyl-4,5-dihydro-1<i>H</i>-pyrazole-4-carboxylicacidmethylester 

[1]IstanbulUniversitesiFenFakultesiMecmuasi,SeriA:Matematik-Fizik-Kimya,1948,vol.13,p.127    Chem.Abstr.,1948,p.8190

[1]AdvancedSynthesisandCatalysis,2018,vol.360,p.3553-3562

[2]Patent:DE847287,1951,    DRP/DRBPOrg.Chem.,

[3]Patent:DE847287,1951,    DRP/DRBPOrg.Chem.,

[4]Patent:DE847287,1951,    DRP/DRBPOrg.Chem.,

[5]Patent:DE945987,1956,

[6]JustusLiebigsAnnalenderChemie,1890,vol.259,p.141

[7]IstanbulUniversitesiFenFakultesiMecmuasi,SeriA:Matematik-Fizik-Kimya,1948,vol.13,p.127    Chem.Abstr.,1948,p.8190

[8]Patent:DE847287,1951,    DRP/DRBPOrg.Chem.,

[9]JournalofOrganicChemistry,1992,vol.57,p.6684-6686

[10]Patent:US4600775,1986,A

[11]Patent:US4789742,1988,A

[12]Patent:JP2017/66132,2017,A.Locationinpatent:Paragraph0019;0021;0024-0026

[1]JournalofPharmaceuticalSciences,1984,vol.73,p.1767-1771

[2]BulletindesSocietesChimiquesBelges,1937,vol.46,p.197

[1]JournaloftheAmericanChemicalSociety,1956,vol.78,p.3069,3071

557-24-4    111-26-2   
<i>N</i>2-hexyl-DL-asparagine 

[1]JournaloftheAmericanChemicalSociety,1956,vol.78,p.3069,3071

Literature

Title: Novel comb-shaped PEG modification enhances the osteoclastic inhibitory effect and bone delivery of osteoprotegerin after intravenous administration in ovariectomized rats.

Journal: Pharmaceutical research 20121101

Title: Formation of self-aggregated structures of different types in water of chiral polymerizable amphiphiles from L-tyrosine and L-phenylalanine.

Journal: Langmuir : the ACS journal of surfaces and colloids 20120626

Title: Prodrugs of acyclovir--a computational approach.

Journal: Chemical biology & drug design 20120501

Title: Computer-assisted design for atenolol prodrugs for the use in aqueous formulations.

Journal: Journal of molecular modeling 20120401

Title: Structure and catalytic mechanism of nicotinate (vitamin B3) degradative enzyme maleamate amidohydrolase from Bordetella bronchiseptica RB50.

Journal: Biochemistry 20120110

Title: New 4-maleamic acid and 4-maleamide peptidyl chalcones as potential multitarget drugs for human prostate cancer.

Journal: Pharmaceutical research 20110401

Title: PEGylation of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) results in decreased uptake into rats and human liver.

Journal: The Journal of pharmacy and pharmacology 20100801

Title: Selective adsorption of D- and L-phenylalanine on molecularly-imprinted polymerized organogels formed using polymerizable gelator N-octadecyl maleamic acid.

Journal: Journal of separation science 20081201

Title: Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20080812

Title: Study of graft copolymerization of N-maleamic acid-chitosan and butyl acrylate by gamma-ray irradiation.

Journal: International journal of biological macromolecules 20050701

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 557-24-4
Tags:557-24-4 Molecular Formula|557-24-4 MDL|557-24-4 SMILES|557-24-4 Maleamic acid