Home Amines 56-10-0
56-10-0,MFCD00037011
Catalog No.:AA003EO3

56-10-0 | 2-(2-Aminoethyl)isothiourea dihydrobromide

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Purity
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Price(USD)
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1g
95%
in stock  
$18.00   $13.00
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5g
95%
in stock  
$43.00   $30.00
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10g
≥98%
in stock  
$48.00   $33.00
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25g
≥98%
in stock  
$85.00   $59.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003EO3
Chemical Name:
2-(2-Aminoethyl)isothiourea dihydrobromide
CAS Number:
56-10-0
Molecular Formula:
C3H11Br2N3S
Molecular Weight:
281.0125
MDL Number:
MFCD00037011
SMILES:
NCCSC(=N)N.Br.Br
Properties
Properties
 
BP:
231.1°C at 760 mmHg  
Form:
Solid  
MP:
190-196 °C(lit.)  
Solubility:
50g/l  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
63.2  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  

Downstream Synthesis Route

[1]Dohertyetal.[JournaloftheAmericanChemicalSociety,1957,vol.79,p.5667,5670]

[2]Schoeberl;Hansen[ChemischeBerichte,1958,vol.91,p.1239]

[3]Khymetal.[JournaloftheAmericanChemicalSociety,1957,vol.79,p.5663,5664,][JournaloftheAmericanChemicalSociety,1958,vol.80,p.3342,3344]

[1]Khymetal.[JournaloftheAmericanChemicalSociety,1957,vol.79,p.5663,5664,][JournaloftheAmericanChemicalSociety,1958,vol.80,p.3342,3344]KOCH;SCHWARZE[Arzneimittel-Forschung/DrugResearch,1957,vol.7,#9,p.576-579]

[2]Hino;Tana-ami;Yamada;Akaboshi[Chemicalandpharmaceuticalbulletin,1966,vol.14,#11,p.1193-1201]

[3]Hallas,M.D.etal.[JournaloftheChemicalSociety,SectionD:ChemicalCommunications,1971,p.1506-1507]

[4]Mandrugin,A.A.;Fedoseev,V.M.;Khomutov,S.M.;Rodyunin,A.A.;Leshchev,Yu.A.[ChemistryofHeterocyclicCompounds,1987,vol.23,#11,p.1262-1266][KhimiyaGeterotsiklicheskikhSoedinenii,1987,#11,p.1572-1575]

[5]Foye;An;Maher[JournalofPharmaceuticalSciences,1984,vol.73,#8,p.1168-1170]

[1]Hino;Tana-ami;Yamada;Akaboshi[Chemicalandpharmaceuticalbulletin,1966,vol.14,#11,p.1193-1201]Bergmann;Kaluszyner[RecueildesTravauxChimiquesdesPays-Bas,1959,vol.78,p.289,309]

[2]Hino;Tana-ami;Yamada;Akaboshi[Chemicalandpharmaceuticalbulletin,1966,vol.14,#11,p.1193-1201]

[3]Foye,W.O.etal.[JournalofMedicinalChemistry,1963,vol.6,p.509-512]

[4]Foye;Hebb;Mickles[JournalofPharmaceuticalSciences,1967,vol.56,#2,p.292-293]

[1]Foye,W.O.etal.[JournalofMedicinalChemistry,1963,vol.6,p.509-512]

[1]FIELD;FERRETTI;CRENSHAW;OWEN[Journalofmedicinalchemistry,1964,vol.7,p.39-44]

Literature

Title: Anti-T haemolysins: the effects of sialic acid removal and 2-aminoethylisothiouronium bromide treatment of erythrocytes on immune lysis.

Journal: Vox sanguinis 20110501

Title: Kinetic evaluation of aminoethylisothiourea on mushroom tyrosinase activity.

Journal: Applied biochemistry and biotechnology 20101001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Radioprotective effects of quercetin and ethanolic extract of propolis in gamma-irradiated mice.

Journal: Arhiv za higijenu rada i toksikologiju 20090601

Title: The role of nitric oxide in radiation damage.

Journal: Biological & pharmaceutical bulletin 20070601

Title: Intracellular and extracellular NO differentially modulates the stress response and apoptosis in macrophages exposed to the influence of biological or physical factors.

Journal: Bulletin of experimental biology and medicine 20070601

Title: Polyamines induce rapid biosynthesis of nitric oxide (NO) in Arabidopsis thaliana seedlings.

Journal: Plant & cell physiology 20060301

Title: Nitric oxide involvement in the delayed antiarrhythmic effect of treadmill exercise in dogs.

Journal: Life sciences 20050902

Title: Association between the expression of inducible nitric oxide synthase by chondrocytes and its nitric oxide-generating activity in adjuvant arthritis in rats.

Journal: Nitric oxide : biology and chemistry 20030501

Title: Enhancement of antiradiation potential of some aminothiols by beta-carotene.

Journal: Annals of nutrition & metabolism 20030101

Title: Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system.

Journal: Neoplasia (New York, N.Y.) 20020701

Title: [Study of the antiradical and radioprotective properties of S-containing compounds using the complex of in vitro test-systems].

Journal: Radiatsionnaia biologiia, radioecologiia 20020101

Title: Osteopontin is induced by nitric oxide in RAW 264.7 cells.

Journal: IUBMB life 20000301

Title: Certain S-substituted isothioureas not only inhibit NO synthase catalytic activity but also decrease translation and stability of inducible NO synthase protein.

Journal: Nitric oxide : biology and chemistry 19980101

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