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56-47-3,MFCD00003660
Catalog No.:AA00I9WZ

56-47-3 | Pregn-4-ene-3,20-dione, 21-(acetyloxy)-

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1g
≥95%
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$63.00   $44.00
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5g
≥95%
in stock  
$246.00   $172.00
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10g
≥95%
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$459.00   $321.00
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25g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I9WZ
Chemical Name:
Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
CAS Number:
56-47-3
Molecular Formula:
C23H32O4
Molecular Weight:
372.4978
MDL Number:
MFCD00003660
SMILES:
CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C
Properties
Computed Properties
 
Complexity:
707  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
3.1  

Literature

Title: Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction.

Journal: Circulation 20161101

Title: Treatment with heme arginate alleviates adipose tissue inflammation and improves insulin sensitivity and glucose metabolism in a rat model of Human primary aldosteronism.

Journal: Free radical biology & medicine 20121215

Title: Implication of CD38 gene in podocyte epithelial-to-mesenchymal transition and glomerular sclerosis.

Journal: Journal of cellular and molecular medicine 20120801

Title: Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension.

Journal: American journal of physiology. Heart and circulatory physiology 20120601

Title: A custom rat and baboon hypertension gene array to compare experimental models.

Journal: Experimental biology and medicine (Maywood, N.J.) 20120101

Title: Identification of benzoxazin-3-one derivatives as novel, potent, and selective nonsteroidal mineralocorticoid receptor antagonists.

Journal: Journal of medicinal chemistry 20111222

Title: Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.

Journal: Kidney international 20110701

Title: Heme arginate suppresses cardiac lesions and hypertrophy in deoxycorticosterone acetate-salt hypertension.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090701

Title: Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a.

Journal: Hypertension (Dallas, Tex. : 1979) 20080701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Search of chemical scaffolds for novel antituberculosis agents.

Journal: Journal of biomolecular screening 20050401

Title: Heme oxygenase-mediated endothelial dysfunction in DOCA-salt, but not in spontaneously hypertensive, rat arterioles.

Journal: American journal of physiology. Heart and circulatory physiology 20040501

Title: Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist.

Journal: Hypertension (Dallas, Tex. : 1979) 19950401

Title: Effect of indomethacin on desoxycorticosterone acetate-sodium chloride-induced renal lesions in the pregnant rat and her offspring.

Journal: Developmental pharmacology and therapeutics 19800101

Title: Lu NZ, et al. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol Rev. 2006 Dec;58(4):782-97. 

Title: Lother A, et al. Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure. Hypertension. 2016 Jan;67(1):130-8. 

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Tags:56-47-3 Molecular Formula|56-47-3 MDL|56-47-3 SMILES|56-47-3 Pregn-4-ene-3,20-dione, 21-(acetyloxy)-