Home Nitro Compounds 56-57-5
56-57-5,MFCD00006738
Catalog No.:AA003LTW

56-57-5 | 4-Nitroquinoline n-oxide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$15.00   $11.00
- +
1g
98%
in stock  
$39.00   $28.00
- +
5g
98%
in stock  
$141.00   $99.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003LTW
Chemical Name:
4-Nitroquinoline n-oxide
CAS Number:
56-57-5
Molecular Formula:
C9H6N2O3
Molecular Weight:
190.1555
MDL Number:
MFCD00006738
SMILES:
O=N(=O)c1cc[n+](c2c1cccc2)[O-]
NSC Number:
19645
UN Number:
2811
Properties
Properties
 
Form:
Solid  
MP:
>153°C (dec.)  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
229  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
XLogP3:
1.1  

Literature

Title: The development of an in vitro Pig-a assay in L5178Y cells.

Journal: Archives of toxicology 20180401

Title: Cortactin is a prognostic marker for oral squamous cell carcinoma and its overexpression is involved in oral carcinogenesis.

Journal: Environmental toxicology 20170301

Title: Intracellular and extracellular factors influencing the genotoxicity of nitric oxide and reactive oxygen species.

Journal: Oncology letters 20170301

Title: Taiwanin C selectively inhibits arecoline and 4-NQO-induced oral cancer cell proliferation via ERK1/2 inactivation.

Journal: Environmental toxicology 20170101

Title: The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.

Journal: Mutagenesis 20160301

Title: The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140701

Title: Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays.

Journal: Environmental and molecular mutagenesis 20131201

Title: Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.

Journal: The Journal of biological chemistry 20130517

Title: Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121201

Title: Interactions of sulforaphane and dimethyl sulfoxide with methyl methanesulfonate, urethane, 4-nitroquinoline-1-oxide and hydrogen peroxide in the Drosophila melanogaster wing spot test.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121201

Title: Modification of the umu-assay (ISO 13829) accounting for cytotoxicity in genotoxicity assessment: a preliminary study.

Journal: Mutation research 20120918

Title: Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer.

Journal: Carcinogenesis 20120901

Title: Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-κB in 4-nitroquinoline 1-oxide-induced murine oral cancer model.

Journal: Toxicology and applied pharmacology 20120715

Title: Confirmation of Frm2 as a novel nitroreductase in Saccharomyces cerevisiae.

Journal: Biochemical and biophysical research communications 20120713

Title: Homeobox C5 expression is associated with the progression of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20120701

Title: Administration of a vaccine composed of dendritic cells pulsed with premalignant oral lesion lysate to mice bearing carcinogen-induced premalignant oral lesions stimulates a protective immune response.

Journal: International immunopharmacology 20120701

Title: Synthesis, study on anti-arthritic, anti-inflammatory activity and toxicity of some novel bis-oxy cyclophane diamides.

Journal: Bioorganic & medicinal chemistry letters 20120601

Title: Alkylation-induced genotoxicity as a predictor of DNA repair deficiency following experimental oral carcinogenesis.

Journal: Journal of molecular histology 20120401

Title: The in vitro toxicology of Swedish snus.

Journal: Critical reviews in toxicology 20120401

Title: Usefulness of combined in vivo skin comet assay and in vivo skin micronucleus test.

Journal: Mutation research 20120318

Title: Food borne yeasts as DNA-bioprotective agents against model genotoxins.

Journal: International journal of food microbiology 20120215

Title: Myeloid-derived suppressor cells contribute to oral cancer progression in 4NQO-treated mice.

Journal: Oral diseases 20120101

Title: The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101

Title: Using DNA damage sensitivity phenotypes to characterize mutations affecting proteasome function.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Good oral health and diet.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Identification of novel human damage response proteins targeted through yeast orthology.

Journal: PloS one 20120101

Title: Role of phosphatidylinositol-3-kinase pathway in head and neck squamous cell carcinoma.

Journal: Journal of oncology 20120101

Title: Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response.

Journal: PloS one 20120101

Title: The influence of organic solvents on estimates of genotoxicity and antigenotoxicity in the SOS chromotest.

Journal: Genetics and molecular biology 20120101

Title: Effective use of the Pig-a gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals.

Journal: The Journal of toxicological sciences 20120101

Title: Vba5p, a novel plasma membrane protein involved in amino acid uptake and drug sensitivity in Saccharomyces cerevisiae.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Green tea polyphenol protection against 4-nitroquinoline 1-oxide-induced bone marrow lipid peroxidation and genotoxicity in Wistar rats.

Journal: Asian Pacific journal of cancer prevention : APJCP 20120101

Title: Use of the in vivo skin comet assay to evaluate the DNA-damaging potential of chemicals applied to the skin.

Journal: Mutation research 20111224

Title: Inhibition of 4-NQO-induced F433 rat tongue carcinogenesis by oleuropein-rich extract.

Journal: Medical oncology (Northwood, London, England) 20111201

Title: Integration of Pig-a, micronucleus, chromosome aberration, and Comet assay endpoints in a 28-day rodent toxicity study with 4-nitroquinoline-1-oxide.

Journal: Environmental and molecular mutagenesis 20111201

Title: Lactobacillus salivarius REN counteracted unfavorable 4-nitroquinoline-1-oxide-induced changes in colonic microflora of rats.

Journal: Journal of microbiology (Seoul, Korea) 20111201

Title: Ethanol promotes chemically induced oral cancer in mice through activation of the 5-lipoxygenase pathway of arachidonic acid metabolism.

Journal: Cancer prevention research (Philadelphia, Pa.) 20111101

Title: A method for detecting genetic toxicity using the RNA synthesis response to DNA damage.

Journal: The Journal of toxicological sciences 20111001

Title: Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells.

Journal: Environmental toxicology and pharmacology 20110901

Title: Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression.

Journal: International journal of cancer 20110715

Title: The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110701

Title: Histological and immunohistochemical evaluation of the chemopreventive role of lycopene in tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.

Journal: Archives of oral biology 20110701

Title: Regenerative capacity in newts is not altered by repeated regeneration and ageing.

Journal: Nature communications 20110701

Title: Chronic restraint stress in oral squamous cell carcinoma.

Journal: Journal of dental research 20110601

Title: 1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis.

Journal: European journal of medicinal chemistry 20110501

Title: Ixr1 is required for the expression of the ribonucleotide reductase Rnr1 and maintenance of dNTP pools.

Journal: PLoS genetics 20110501

Title: Antiproliferative and anticytotoxic effects of cell fractions and exopolysaccharides from Lactobacillus casei 01.

Journal: Mutation research 20110403

Title: Fenofibrate exhibits a high potential to suppress the formation of squamous cell carcinoma in an oral-specific 4-nitroquinoline 1-oxide/arecoline mouse model.

Journal: Biochimica et biophysica acta 20110401

Title: Absence of galectin-3 does not affect the development of experimental tongue carcinomas in mice.

Journal: Experimental and molecular pathology 20110401

Title: Ras gene mutation is not related to tumour invasion during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110401

Title: Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis.

Journal: Carcinogenesis 20110401

Title: Protective effects of sesame oil on 4-NQO-induced oxidative DNA damage and lipid peroxidation in rats.

Journal: Drug and chemical toxicology 20110401

Title: Evaluation of the reproductive and developmental risks of caffeine.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110401

Title: Oxidative DNA damage is a preliminary step during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Journal of molecular histology 20110401

Title: Application of the DNA adductome approach to assess the DNA-damaging capability of in vitro micronucleus test-positive compounds.

Journal: Mutation research 20110318

Title: Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma.

Journal: Cancer prevention research (Philadelphia, Pa.) 20110201

Title: Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion.

Journal: DNA repair 20110102

Title: Protective effect of Spirulina against 4-nitroquinoline-1-oxide induced toxicity.

Journal: Molecular biology reports 20110101

Title: The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.

Journal: Genetics 20110101

Title: An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents.

Journal: PloS one 20110101

Title: Oral carcinogenesis and oral cancer chemoprevention: a review.

Journal: Pathology research international 20110101

Title: DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange.

Journal: PloS one 20110101

Title: Understanding carcinogenesis for fighting oral cancer.

Journal: Journal of oncology 20110101

Title: [SOS response of DNA repair and genetic cell instability under hypoxic conditions].

Journal: Radiatsionnaia biologiia, radioecologiia 20110101

Title: The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.

Journal: PloS one 20110101

Title: Nucleotide Excision Repair in Caenorhabditis elegans.

Journal: Molecular biology international 20110101

Title: Differential modifying effects of food additive butylated hydroxytoluene toward radiation and 4-nitro-quinoline 1-oxide-induced genotoxicity in yeast.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20110101

Title: Estimates of DNA damage by the comet assay in the direct-developing frog Eleutherodactylus johnstonei (Anura, Eleutherodactylidae).

Journal: Genetics and molecular biology 20110101

Title: Evaluation of a modified CD71 MicroFlow method for the flow cytometric analysis of micronuclei in rat bone marrow erythrocytes.

Journal: Mutation research 20101221

Title: Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.

Journal: Cancer research 20101201

Title: Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice.

Journal: Virology 20101110

Title: Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer.

Journal: Cancer research 20101101

Title: Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis.

Journal: Cancer prevention research (Philadelphia, Pa.) 20101101

Title: Malignant transformation of rat bone marrow-derived mesenchymal stem cells treated with 4-nitroquinoline 1-oxide.

Journal: Chemico-biological interactions 20101006

Title: The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA.

Journal: DNA repair 20101005

Title: Interplay of DNA repair, homologous recombination, and DNA polymerases in resistance to the DNA damaging agent 4-nitroquinoline-1-oxide in Escherichia coli.

Journal: DNA repair 20101005

Title: Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice.

Journal: The Journal of nutritional biochemistry 20101001

Title: Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivity.

Journal: The Journal of biological chemistry 20100813

Title: The effect of desalivation on the malignant transformation of the tongue epithelium and associated stromal myofibroblasts in a rat 4-nitroquinoline 1-oxide-induced carcinogenesis model.

Journal: International journal of experimental pathology 20100801

Title: Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100601

Title: Induction of lacZ mutations in MutaMouse primary hepatocytes.

Journal: Environmental and molecular mutagenesis 20100501

Title: Dose-dependent changes in cyclin D1 in response to 4-nitroquinoline 1-oxide-induced DNA damage.

Journal: Archives of biochemistry and biophysics 20100501

Title: Dissection of genetically complex traits with extremely large pools of yeast segregants.

Journal: Nature 20100415

Title: Comet assay in murine bone-marrow cell line (FDC-P2).

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401

Title: Rigid confocal endoscopy for in vivo imaging of experimental oral squamous intra-epithelial lesions.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100401

Title: Relationship between endoplasmic reticulum- and Golgi-associated calcium homeostasis and 4-NQO-induced DNA repair in Saccharomyces cerevisiae.

Journal: Archives of microbiology 20100401

Title: Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100301

Title: Evaluation of chrono-amperometric signal detection for the analysis of genotoxicity by a whole cell biosensor.

Journal: Analytica chimica acta 20100205

Title: Wnt/beta-catenin signalling pathway following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Experimental and molecular pathology 20100201

Title: Enhancement of tongue carcinogenesis in Hras128 transgenic rats treated with 4-nitroquinoline 1-oxide.

Journal: Oncology reports 20100201

Title: The role of matrix metalloproteinases 2 and 9 during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Journal of molecular histology 20100201

Title: Co-treating with arecoline and 4-nitroquinoline 1-oxide to establish a mouse model mimicking oral tumorigenesis.

Journal: Chemico-biological interactions 20100105

Title: Genotoxicity and antigenotoxicity evaluation of non-photoactivated hypericin.

Journal: Phytotherapy research : PTR 20100101

Title: Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

Title: Modulatory role of alizarin from Rubia cordifolia L. against genotoxicity of mutagens.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

Title: Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors.

Journal: Cancer prevention research (Philadelphia, Pa.) 20100101

Title: Simultaneous occurrence of energy transfer and photoinduced electron transfer in interactions of hen egg white lysozyme with 4-nitroquinoline-1-oxide.

Journal: Photochemistry and photobiology 20100101

Title: Rrd1 isomerizes RNA polymerase II in response to rapamycin.

Journal: BMC molecular biology 20100101

Title: Antimutagenicity and antiproliferative studies of lipidic extracts from white shrimp (Litopenaeus vannamei).

Journal: Marine drugs 20100101

Title: A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.

Journal: Cancer prevention research (Philadelphia, Pa.) 20091201

Title: The effect of dietary and topical celecoxib on 4-nitroquinoline-1-oxide-induced lingual epithelium alternations in rat.

Journal: JPMA. The Journal of the Pakistan Medical Association 20091101

Title: Anti- and pro-mutagenic effects of silymarin in the Ames bacterial reverse mutation assay.

Journal: Phytotherapy research : PTR 20091001

Title: Cyclin D1 overexpression increases susceptibility to 4-nitroquinoline-1-oxide-induced dysplasia and neoplasia in murine squamous oral epithelium.

Journal: Molecular carcinogenesis 20090901

Title: Induction of DNA strand breaks by genotoxicants in the alga Chlamydomonas reinhardtii.

Journal: Environmental toxicology and chemistry 20090901

Title: Gene expression analysis in zebrafish embryos: a potential approach to predict effect concentrations in the fish early life stage test.

Journal: Environmental toxicology and chemistry 20090901

Title: Modulatory action of 2-deoxy-D-glucose on mitomycin C-and 4-nitroquinoline-1-oxide-induced genotoxicity in Swiss albino mice in vivo.

Journal: Journal of cancer research and therapeutics 20090901

Title: Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17.

Journal: Arthritis and rheumatism 20090801

Title: p16(CDKN2A) expression during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.

Journal: Oral oncology 20090701

Title: Increased expression of focal adhesion kinase correlates with cellular proliferation and apoptosis during 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20090701

Title: Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus.

Journal: Cancer science 20090701

Title: Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen.

Journal: Cancer biology & therapy 20090701

Title: Lecithin:retinol acyltransferase and retinyl esters: is balance the essence in carcinogenesis?

Journal: Cancer biology & therapy 20090701

Title: Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma.

Journal: Oncogene 20090625

Title: Evaluation of antigenotoxic activity of isoliquiritin apioside from Glycyrrhiza glabra L.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090601

Title: Animal models of cancer in the head and neck region.

Journal: Clinical and experimental otorhinolaryngology 20090601

Title: A mouse model for oral squamous cell carcinoma.

Journal: Journal of molecular histology 20090601

Title: Expression of gap junctional protein connexin43 during 4-nitroquinoline-1-oxide-induced rat tongue carcinogenesis.

Journal: Journal of molecular histology 20090601

Title: Effect of dietary and topical Celecoxib on expression of bcl-2, bax, c-erb-B2 and Ki67 in carcinogen-induced tongue carcinoma in rat.

Journal: Pakistan journal of biological sciences : PJBS 20090515

Title: Stimulation of direct-repeat recombination by RNA polymerase III transcription.

Journal: DNA repair 20090501

Title: Diabetes enhances the expression of H-ras and suppresses the expression of EGFR leading to increased cell proliferation.

Journal: Histology and histopathology 20090501

Title: Introduction of a normal human chromosome 8 corrects abnormal phenotypes of Werner syndrome cells immortalized by expressing an hTERT gene.

Journal: Journal of radiation research 20090501

Title: Performance of the comet assay in a high-throughput version.

Journal: Mutation research 20090430

Title: ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

Journal: Cancer prevention research (Philadelphia, Pa.) 20090401

Title: N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.

Journal: Bioorganic & medicinal chemistry 20090315

Title: Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma.

Journal: Cancer research 20090315

Title: A novel immunocompetent murine model for Candida albicans-promoted oral epithelial dysplasia.

Journal: Medical mycology 20090301

Title: DNA repair phenotype and cancer susceptibility--a mini review.

Journal: International journal of cancer 20090301

Title: [Expression of survivin, Bcl-2 and p53 during 4-nitro-quinoline 1-oxide-induced rat tongue carcinogenesis].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20090301

Title: Potential genotoxicity of plant extracts used in Ethiopian traditional medicine.

Journal: Journal of ethnopharmacology 20090225

Title: No mutations found in exon 2 of gene p16CDKN2A during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.

Journal: Journal of molecular histology 20090201

Title: FDG-PET/CT of head and neck squamous cell carcinoma in a rat model.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101

Title: Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model.

Journal: Cancer prevention research (Philadelphia, Pa.) 20090101

Title: Evaluation of cytotoxic and cytostatic effects in Saccharomyces cerevisiae by poissoner quantitative drop test.

Journal: Basic & clinical pharmacology & toxicology 20090101

Title: Reactive oxygen species and autophagy play a role in survival and differentiation of the phytopathogen Moniliophthora perniciosa.

Journal: Fungal genetics and biology : FG & B 20090101

Title: Genotoxic damage of human adipose-tissue derived mesenchymal stem cells triggers their terminal differentiation.

Journal: Neoplasma 20090101

Title: Antigenotoxic and antioxidant potential of aqueous fraction of ethanol extract of Mentha spicata (L.) against 4-nitroquinoline-1-oxide-induced chromosome damage in mice.

Journal: Drug and chemical toxicology 20090101

Title: Assessment of Damage to Nucleic Acids and Repair Machinery in Salmonella typhimurium Exposed to Chlorine.

Journal: International journal of microbiology 20090101

Title: Discrimination of carcinogens by hepatic transcript profiling in rats following 28-day administration.

Journal: Cancer informatics 20090101

Title: Imbalance of tumor suppression genes expression following rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: In vivo (Athens, Greece) 20090101

Title: Eosinophils and oral squamous cell carcinoma: a short review.

Journal: Journal of oncology 20090101

Title: Protective effects of solvent fractions of Mentha spicata (L.) leaves evaluated on 4-nitroquinoline-1-oxide induced chromosome damage and apoptosis in mouse bone marrow cells.

Journal: Genetics and molecular biology 20090101

Title: Cytogenotoxicity biomarkers in fat snook Centropomus parallelus from Cananéia and São Vicente estuaries, SP, Brazil.

Journal: Genetics and molecular biology 20090101

Title: Increased antimutagenic and anticlastogenic effects of doenjang (Korean fermented soybean paste) prepared with bamboo salt.

Journal: Journal of medicinal food 20081201

Title: Glutathione transferases from Anguilla anguilla liver: identification, cloning and functional characterization.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20081020

Title: Genomic instability in blood cells is able to predict the oral cancer risk: an experimental study in rats.

Journal: Journal of molecular histology 20081001

Title: 3-Eth-oxy-4-hydroxy-benzaldehyde.

Journal: Acta crystallographica. Section E, Structure reports online 20081001

Title: Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.

Journal: Mutation research 20080926

Title: Antioxidative and antimutagenic activities of 70% ethanol extract from masou salmon (Oncorhynchus masou).

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080901

Title: Lack of promotion activity of diacylglycerol oil on 4-nitroquinoline 1-oxide induced carcinogenesis in the oral cavity of SD rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901

Title: Apoptin induces apoptosis in an oral cancer mouse model.

Journal: Cancer biology & therapy 20080901

Title: Raw milk traditional Italian ewe cheeses as a source of Lactobacillus casei strains with acid-bile resistance and antigenotoxic properties.

Journal: International journal of food microbiology 20080731

Title: Sensitivity of RECQL4-deficient fibroblasts from Rothmund-Thomson syndrome patients to genotoxic agents.

Journal: Human genetics 20080701

Title: Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast.

Journal: PLoS genetics 20080701

Title: Carbon source-dependent variation of acquired mutagen resistance of Moniliophthora perniciosa: similarities in natural and artificial systems.

Journal: Fungal genetics and biology : FG & B 20080601

Title: PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40.

Journal: Molecular cell 20080523

Title: Chemopreventive and therapeutic modulation of green tea polyphenols on drug metabolizing enzymes in 4-Nitroquinoline 1-oxide induced oral cancer.

Journal: Chemico-biological interactions 20080415

Title: Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.

Journal: Journal of medicinal chemistry 20080410

Title: The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata.

Journal: Molecular microbiology 20080401

Title: Elongating RNA polymerase II is disassembled through specific degradation of its largest but not other subunits in response to DNA damage in vivo.

Journal: The Journal of biological chemistry 20080314

Title: Antimutagenicity of hops (Humulus lupulus L.): bioassay-directed fractionation and isolation of xanthohumol.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301

Title: Prevention of upper aerodigestive tract cancer in zinc-deficient rodents: inefficacy of genetic or pharmacological disruption of COX-2.

Journal: International journal of cancer 20080301

Title: Functional characterization of the putative Aspergillus nidulans DNA damage binding protein homologue DdbA.

Journal: Molecular genetics and genomics : MGG 20080301

Title: In vitro inhibitory activity of probiotic spore-forming bacilli against genotoxins.

Journal: Letters in applied microbiology 20080301

Title: High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20080301

Title: Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer.

Journal: British journal of cancer 20080226

Title: A novel rasH2 mouse carcinogenesis model that is highly susceptible to 4-NQO-induced tongue and esophageal carcinogenesis is useful for preclinical chemoprevention studies.

Journal: Carcinogenesis 20080201

Title: Evidence for in vitro anti-genotoxicity of cheese non-starter lactobacilli.

Journal: Antonie van Leeuwenhoek 20080101

Title: Antigenotoxic effect of extract from Cynara cardunculus L.

Journal: Phytotherapy research : PTR 20080101

Title: [Effects of 50 Hz magnetic fields on DNA double-strand breaks in human lens epithelial cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20080101

Title: Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro.

Journal: Diabetes/metabolism research and reviews 20080101

Title: Use of carcinogen-induced premalignant oral lesions in a dendritic cell-based vaccine to stimulate immune reactivity against both premalignant oral lesions and oral cancer.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20080101

Title: Electromagnetic noise inhibits radiofrequency radiation-induced DNA damage and reactive oxygen species increase in human lens epithelial cells.

Journal: Molecular vision 20080101

Title: Suppression of mutagens-induced SOS response by phytoncide solution using Salmonella typhimurium TA1535/pSK1002 umu test.

Journal: Journal of oleo science 20080101

Title: Characterization of a new rat model of head and neck squamous cell carcinoma.

Journal: In vivo (Athens, Greece) 20080101

Title: 4NQO-induced rat tongue carcinoma: an ultrastructural study.

Journal: Ultrastructural pathology 20080101

Title: Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide.

Journal: Mutation research 20071201

Title: Increased risk of oral cancer in diabetic animals is not associated with c-jun activation pathway.

Journal: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20071201

Title: Sympathectomy decreases size and invasiveness of tongue cancer in rats.

Journal: Neuroscience 20071109

Title: Stromal myofibroblasts and malignant transformation in a 4NQO rat tongue carcinogenesis model.

Journal: Oral oncology 20071101

Title: Werner syndrome helicase (WRN), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome.

Journal: Cell biology international 20071001

Title: Placental glutathione S-transferase correlates with cellular proliferation during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070901

Title: Mutagenic and antimutagenic effects of methanol extracts of unfermented and fermented black soybeans.

Journal: International journal of food microbiology 20070815

Title: Lycopene activity against chemically induced DNA damage in Chinese hamster ovary cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070801

Title: Survivin and inducible nitric oxide synthase production during 4NQO-induced rat tongue carcinogenesis: a possible relationship.

Journal: Experimental and molecular pathology 20070801

Title: [Establishment and identification of biological characteristics of rat monoclone cell line Rca-B].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20070801

Title: Antigenotoxic effects of the phytoestrogen pelargonidin chloride and the polyphenol chlorogenic acid.

Journal: Molecular nutrition & food research 20070701

Title: Possible enhancing activity of diacylglycerol on 4-nitroquinoline 1-oxide induced carcinogenesis of the tongue in human c-Ha-ras proto-oncogene transgenic rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070601

Title: WRN functions in a RAD18-dependent damage avoidance pathway.

Journal: Biological & pharmaceutical bulletin 20070601

Title: Enhanced levels of glutathione and protein glutathiolation in rat tongue epithelium during 4-NQO-induced carcinogenesis.

Journal: International journal of cancer 20070401

Title: Possible mechanisms of antimutagenicity in fermented soymilk prepared with a coculture of Streptococcus infantis and Bifidobacterium infantis.

Journal: Journal of food protection 20070401

Title: Toxicogenomic responses in rainbow trout (Oncorhynchus mykiss) hepatocytes exposed to model chemicals and a synthetic mixture.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20070310

Title: A prostaglandin E2 receptor subtype EP1-selective antagonist, ONO-8711, suppresses 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Carcinogenesis 20070301

Title: Attenuation of 4-nitroquinoline 1-oxide induced in vitro lipid peroxidation by green tea polyphenols.

Journal: Life sciences 20070227

Title: 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway.

Journal: Toxicology 20070212

Title: Connexin expression in mouse lung tumor.

Journal: Cancer letters 20070208

Title: Frequent mutation of p16(CDKN2A) exon 1 during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.

Journal: Molecular carcinogenesis 20070201

Title: Effects of sex hormones on rat tongue carcinoma induced by 4-nitroquinoline 1-oxide (4NQO).

Journal: The Bulletin of Tokyo Dental College 20070201

Title: A method to distinguish between the de novo induction of thymidine kinase mutants and the selection of pre-existing thymidine kinase mutants in the mouse lymphoma assay.

Journal: Mutation research 20070110

Title: 4-Nitroquinoline-1-oxide-induced mutagen sensitivity and risk of nonmelanoma skin cancer: a case-control analysis.

Journal: The Journal of investigative dermatology 20070101

Title: Methyl-substituted 4-nitropyridine N-oxides as ligands: structural, spectroscopic, magnetic and cytotoxic characteristics of copper(II) complexes.

Journal: Journal of inorganic biochemistry 20070101

Title: Response of lymphocyte subsets and cytokines to Shenyang prescription in Sprague-Dawley rats with tongue squamous cell carcinomas induced by 4NQO.

Journal: BMC cancer 20070101

Title: Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer.

Journal: BMC evolutionary biology 20070101

Title: Initial in vitro screening approach to investigate the potential health and environmental hazards of Enviroxtrade mark - a nanoparticulate cerium oxide diesel fuel additive.

Journal: Particle and fibre toxicology 20070101

Title: Deletion of the chromatin remodeling gene SPT10 sensitizes yeast cells to a subclass of DNA-damaging agents.

Journal: Environmental and molecular mutagenesis 20061201

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Nitrocompound activation by cell-free extracts of nitroreductase-proficient Salmonella typhimurium strains.

Journal: Mutagenesis 20061101

Title: Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts.

Journal: Cancer letters 20060908

Title: Chemopreventive efficacy of all-trans-retinoic acid in biodegradable microspheres against epithelial cancers: results in a 4-nitroquinoline 1-oxide-induced oral carcinogenesis model.

Journal: International journal of pharmaceutics 20060831

Title: Modulatory efficacy of green tea polyphenols on glycoconjugates and immunological markers in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis-A therapeutic approach.

Journal: Chemico-biological interactions 20060825

Title: Mutagenicity and antimutagenic effect of soymilk fermented with lactic acid bacteria and bifidobacteria.

Journal: International journal of food microbiology 20060815

Title: 4-nitroquinoline-1-oxide induced experimental oral carcinogenesis.

Journal: Oral oncology 20060801

Title: Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers.

Journal: Oral oncology 20060801

Title: Role of the ABC transporter TruMDR2 in terbinafine, 4-nitroquinoline N-oxide and ethidium bromide susceptibility in Trichophyton rubrum.

Journal: Journal of medical microbiology 20060801

Title: Development of genotoxicity test procedures with Episkin, a reconstructed human skin model: towards new tools for in vitro risk assessment of dermally applied compounds?

Journal: Mutation research 20060714

Title: Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice.

Journal: Carcinogenesis 20060701

Title: Suppression on the mutagenicity of 4-nitroquinoline-N-oxide by the methanol extracts of soybean koji prepared with various filamentous fungi.

Journal: International journal of food microbiology 20060701

Title: Use of fish in vitro hepatocyte assays to detect multi-endpoint toxicity in Slovenian river sediments.

Journal: Marine environmental research 20060701

Title: Kre29p is a novel nuclear protein involved in DNA repair and mitotic fidelity in Candida glabrata.

Journal: Current genetics 20060701

Title: Immunohistochemical evaluation of metallothionein in palatal mucosal cells of mice treated with 4NQO.

Journal: Medicina oral, patologia oral y cirugia bucal 20060701

Title: 4-nitroquinoline-1-oxide induces the formation of cellular topoisomerase I-DNA cleavage complexes.

Journal: Cancer research 20060701

Title: Mutagen sensitivity has high heritability: evidence from a twin study.

Journal: Cancer research 20060615

Title: 4-Nitroquinoline 1-oxide forms 8-hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060601

Title: p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer.

Journal: Molecular cancer research : MCR 20060601

Title: Effects of co-exposure to extremely low frequency (50 Hz) magnetic fields and xenobiotics determined in vitro by the alkaline comet assay.

Journal: The Science of the total environment 20060515

Title: Interaction of 4-nitroquinoline-1-oxide with indole derivatives and some related biomolecules: a study with magnetic field.

Journal: The journal of physical chemistry. B 20060504

Title: Broken hyphae of the basidiomycete Crinipellis perniciosa allow quantitative assay of toxicity.

Journal: Current microbiology 20060501

Title: Ultrastructural changes of the palatal mucosa following application of 4-nitroquinoline-l-oxide (4NQO) in rats subjected to major salivary gland excision.

Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060401

Title: An animal model for the rapid induction of tongue neoplasms in human c-Ha-ras proto-oncogene transgenic rats by 4-nitroquinoline 1-oxide: its potential use for preclinical chemoprevention studies.

Journal: Carcinogenesis 20060301

Title: Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO.

Journal: Oral oncology 20060201

Title: A speed congenic rat strain bearing the tongue cancer susceptibility locus Tscc1 from Dark-Agouti rats.

Journal: Cancer letters 20060118

Title: Mutagenesis.

Journal: Methods in molecular biology (Clifton, N.J.) 20060101

Title: Genotoxicity of dental resin polymerization initiators in vitro.

Journal: Journal of materials science. Materials in medicine 20060101

Title: [Cellular mechanisms of induction of apoptosis in human erythroleukaemic K562 cells line treated by quinoline-N-oxide derivatives].

Journal: Biomeditsinskaia khimiia 20060101

Title: Expression of receptor for advanced glycation end products during rat tongue carcinogenesis by 4-nitroquinoline 1-oxide and effect of a selective cyclooxygenase-2 inhibitor, etodolac.

Journal: Pathobiology : journal of immunopathology, molecular and cellular biology 20060101

Title: Abnormal expression of bcl-2 and bax in rat tongue mucosa during the development of squamous cell carcinoma induced by 4-nitroquinoline 1-oxide.

Journal: International journal of experimental pathology 20051201

Title: Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents.

Journal: DNA repair 20051121

Title: Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro.

Journal: Mutation research 20051015

Title: Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment.

Journal: Cancer research 20050901

Title: The role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice: tumor-promoting action through the induction of oxidative stress.

Journal: Toxicology letters 20050814

Title: Genome-wide requirements for resistance to functionally distinct DNA-damaging agents.

Journal: PLoS genetics 20050801

Title: Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome.

Journal: Oncogene 20050728

Title: Screening of potential lactobacilli antigenotoxicity by microbial and mammalian cell-based tests.

Journal: International journal of food microbiology 20050625

Title: [Modulation of Chinese prescription Shenyang on Th1/Th2 cytokines in serum of SD rats with squamous cell carcinoma of the tongue].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20050601

Title: [Influence of 1.8 GHz microwave on DNA damage induced by 4 chemical mutagens].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20050601

Title: Chemoprevention of 4-NQO-induced oral carcinogenesis by co-administration of all-trans retinoic acid loaded microspheres and celecoxib.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20050505

Title: Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats.

Journal: Cancer letters 20050418

Title: Genotoxicity evaluation of electromagnetic fields generated by 835-MHz mobile phone frequency band.

Journal: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20050401

Title: 4NQO oral carcinogenesis: animal models, molecular markers and future expectations.

Journal: Oral oncology 20050401

Title: Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1.

Journal: Biochemistry 20050322

Title: [Modulation of Chinese regimen granules of Shenyang on peripheral blood lymphocyte subsets of SD rats with SCC of tongue].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20050301

Title: p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment.

Journal: The international journal of biochemistry & cell biology 20050201

Title: Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats.

Journal: Journal of the National Cancer Institute 20050105

Title: Genetic predisposition to 4NQO-induced tongue carcinogenesis in the rat.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

Title: Differential regulation of gene expression by RNA polymerase II in response to DNA damage.

Journal: Biochemical and biophysical research communications 20041217

Title: Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20041201

Title: Antigenotoxic potential of glucomannan on four model test systems.

Journal: Cell biology and toxicology 20041101

Title: Therapeutic efficacy of green tea polyphenols on cellular thiols in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis.

Journal: Chemico-biological interactions 20041015

Title: Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping.

Journal: Molecular cell 20041008

Title: Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Oral oncology 20041001

Title: Ectopic expression of tyrosinase increases melanin synthesis and cell death following UVB irradiation in fibroblasts from familial atypical multiple mole and melanoma (FAMMM) patients.

Journal: Melanoma research 20041001

Title: The yeast phosphotyrosyl phosphatase activator protein, yPtpa1/Rrd1, interacts with Sit4 phosphatase to mediate resistance to 4-nitroquinoline-1-oxide and UVA.

Journal: Current genetics 20040801

Title: High frequency methylation of p16INK4A gene during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Oncology reports 20040701

Title: The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.

Journal: DNA repair 20040603

Title: Effects of genotoxic compounds on DNA and development of early and late grass shrimp embryo stages.

Journal: Marine environmental research 20040601

Title: On the relevance of genotoxicity for fish populations I: effects of a model genotoxicant on zebrafish (Danio rerio) in a complete life-cycle test.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040528

Title: On the relevance of genotoxicity for fish populations II: genotoxic effects in zebrafish (Danio rerio) exposed to 4-nitroquinoline-1-oxide in a complete life-cycle test.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040528

Title: Genotoxicity of tamoxifen citrate and 4-nitroquinoline-1-oxide in the wing spot test of Drosophila melanogaster.

Journal: Mutagenesis 20040501

Title: Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair.

Journal: Free radical biology & medicine 20040415

Title: Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair.

Journal: Genetics 20040401

Title: Enhanced stimulation of chromosomal translocations by radiomimetic DNA damaging agents and camptothecin in Saccharomyces cerevisiae rad9 checkpoint mutants.

Journal: Mutation research 20040322

Title: Interaction between the immune system and tongue squamous cell carcinoma induced by 4-nitroquinoline N-oxide in mice.

Journal: Oral oncology 20040301

Title: The Neurospora crassa mus-19 gene is identical to the qde-3 gene, which encodes a RecQ homologue and is involved in recombination repair and postreplication repair.

Journal: Current genetics 20040201

Title: Investigation of the antimutagenic effects of selected South African medicinal plant extracts.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20040201

Title: Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers.

Journal: Pathology international 20040101

Title: A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation.

Journal: Experimental cell research 20040101

Title: Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040101

Title: Anti-stress activity of Propionibacterium freudenreichii : identification of a reactivative protein.

Journal: Antonie van Leeuwenhoek 20040101

Title: Apple phytochemicals and their health benefits.

Journal: Nutrition journal 20040101

Title: Transgenerational transmission of radiation- and chemically induced tumors and congenital anomalies in mice: studies of their possible relationship to induced chromosomal and molecular changes.

Journal: Cytogenetic and genome research 20040101

Title: Development of a genotoxicity detection system using a biosensor.

Journal: Environmental sciences : an international journal of environmental physiology and toxicology 20040101

Title: The protective effect of mild hyperthermia against UV-mimetic agent 4-nitroquinoline-1-oxide (4NQO) in human colon cells.

Journal: Research communications in molecular pathology and pharmacology 20040101

Title: p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene.

Journal: The American journal of pathology 20031101

Title: Changing expression of E- and P-cadherin during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20031001

Title: Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination.

Journal: Genetics 20031001

Title: Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide.

Journal: Cancer letters 20030925

Title: Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks.

Journal: Cancer research 20030801

Title: [Heat shock inhibits the induced expression of the SOS genes and SoxRS regulons in Escherichia coli].

Journal: Genetika 20030801

Title: Histomorphologic and morphometric changes in minor salivary glands of the rat tongue during 4-nitroquinoline-1-oxide-induced carcinogenesis.

Journal: Oral oncology 20030701

Title: Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide.

Journal: Oral oncology 20030701

Title: The Schizosaccharomyces pombe cdt2(+) gene, a target of G1-S phase-specific transcription factor complex DSC1, is required for mitotic and premeiotic DNA replication.

Journal: Genetics 20030701

Title: Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.

Journal: Mutation research 20030420

Title: Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor gamma ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide.

Journal: Cancer science 20030401

Title: Modulation of mutagenicity of various mutagens by lignin derivatives.

Journal: Mutation research 20030303

Title: Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay.

Journal: Mutagenesis 20030301

Title: Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue rat tongue epithelial cells and fibroblasts.

Journal: Mutation research 20030128

Title: A COX-2 inhibitor, nimesulide, inhibits chemically-induced rat tongue carcinogenesis through suppression of cell proliferation activity and COX-2 and iNOS expression.

Journal: Histology and histopathology 20030101

Title: A novel geranylated derivative, ethyl 3-(4'-geranyloxy-3'-methoxyphenyl)-2-propenoate, synthesized from ferulic acid suppresses carcinogenesis and inducible nitric oxide synthase in rat tongue.

Journal: Oncology 20030101

Title: Antimutagenic effects of doenjang (Korean fermented soypaste) and its active compounds.

Journal: Mutation research 20030101

Title: [Erythroid differentiation of K562 cells resistant to 2-(4'-dimethylaminostyryl)quinoline 1-oxide or 4-nitroquinoline 1-oxide is significantly increased after thymidine treatment].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20030101

Title: A yeast-based method for the detection of cyto and genotoxicity.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030101

Title: Dietary protocatechuic acid during the progression phase exerts chemopreventive effects on chemically induced rat tongue carcinogenesis.

Journal: Asian Pacific journal of cancer prevention : APJCP 20030101

Title: Carcinogenesis modifier loci in rat tongue are subject to frequent loss of heterozygosity.

Journal: International journal of cancer 20021220

Title: Association of p16(INK4a) and pRb inactivation with immortalization of human cells.

Journal: Carcinogenesis 20021201

Title: Expression of beta-catenin in rat oral epithelial dysplasia induced by 4-nitroquinoline 1-oxide.

Journal: Oral oncology 20021201

Title: Lactic acid bacteria isolated from dairy products inhibit genotoxic effect of 4-nitroquinoline-1-oxide in SOS-chromotest.

Journal: Systematic and applied microbiology 20021201

Title: Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block.

Journal: Oncogene 20021031

Title: Skeletal muscle regeneration associated with the stroma reaction during tumor invasion in the rat tongue.

Journal: Journal of submicroscopic cytology and pathology 20021001

Title: Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients.

Journal: Mutation research 20020926

Title: Genotoxicity is modulated by ascorbic acid. Studies using the wing spot test in Drosophila.

Journal: Mutation research 20020926

Title: Investigation of environmental factors for diagnosing malignant potential in oral epithelial dysplasia.

Journal: Oral oncology 20020901

Title: Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Carcinogenesis 20020801

Title: Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue.

Journal: Mutation research 20020627

Title: Measurement of DNA damage induced by irradiation with gamma-rays from a TRIGA Mark II research reactor in human cells using Fast Micromethod.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20020601

Title: Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501

Title: Dietary silymarin suppresses 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats.

Journal: Carcinogenesis 20020501

Title: A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays.

Journal: Cytometry 20020501

Title: Salmonella typhimurium mutagenicity tester strains that overexpress oxygen-insensitive nitroreductases nfsA and nfsB.

Journal: Mutation research 20020425

Title: Inhibition of 4-nitroquinoline-1-oxide genotoxicity by Bacillus strains.

Journal: Research in microbiology 20020401

Title: [Modification of repair DNA synthesis in mutagen-treated human fibroblasts during adaptive response and the antimutagenic effect of garlic extract].

Journal: Genetika 20020301

Title: [Comparison of the protective effect of garlic extract and cell defense during adaptive response].

Journal: Genetika 20020301

Title: Werner and Bloom helicases are involved in DNA repair in a complementary fashion.

Journal: Oncogene 20020131

Title: Phenotypic consequences of mutations in the conserved motifs of the putative helicase domain of the human Cockayne syndrome group B gene.

Journal: Gene 20020123

Title: Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens.

Journal: Mutation research 20020115

Title: DNA damage and repair in lymphoblastoid cell lines from normal donors and fragile X syndrome patients.

Journal: Archives of medical research 20020101

Title: In vitro protective effects of Terminalia arjuna bark extracts against the 4-nitroquinoline-N-oxide genotoxicity.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101

Title: A novel nucleolar biomarker in plant and animal cells for assessment of substance cytotoxicity.

Journal: Environmental toxicology 20020101

Title: Antimutagenic activity of crown-containing compounds.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20020101

Title: PCNA in palate and tongue mucosal dysplastic lesions induced by topically applied 4NQO in desalivated rat.

Journal: Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20020101

Title: Effects of long-term administration of cancer-promoting substances on oral subepithelial mast cells in the rat.

Journal: Anticancer research 20020101

Title: Oral mucosal carcinogenesis in SENCAR mice.

Journal: Anticancer research 20020101

Title: Different mutation status of the beta-catenin gene in carcinogen-induced colon, brain, and oral tumors in rats.

Journal: Molecular carcinogenesis 20011201

Title: Alteration of pRb expression in the development of rat tongue carcinoma induced by 4-nitroquinoline 1-oxide.

Journal: Oral oncology 20011001

Title: Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli.

Journal: Molecular genetics and genomics : MGG 20011001

Title: CaALK8, an alkane assimilating cytochrome P450, confers multidrug resistance when expressed in a hypersensitive strain of Candida albicans.

Journal: Yeast (Chichester, England) 20010915

Title: Activation of the Escherichia coli SoxRS-regulon by nitric oxide and its physiological donors.

Journal: Biochemistry. Biokhimiia 20010901

Title: The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors.

Journal: Mechanisms of ageing and development 20010801

Title: Epithelial-mesenchymal interactions in experimental oral mucosal carcinogenesis.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010801

Title: Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression.

Journal: Mutation research 20010725

Title: Evaluation of the capacity of the SCGE assay to assess the genotoxicity of biomaterials.

Journal: Biomaterials 20010701

Title: Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies.

Journal: Mutation research 20010602

Title: Evaluation of the toxicity of chemical compounds using digestive acini of the bivalve mollusc Pecten maximus L. maintained alive in vitro.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20010601

Title: Calcium is a key signaling molecule in beta-lapachone-mediated cell death.

Journal: The Journal of biological chemistry 20010601

Title: Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat.

Journal: Japanese journal of cancer research : Gann 20010601

Title: Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic.

Journal: Fitoterapia 20010601

Title: Ethidium bromide and SYBR Green I enhance the genotoxicity of UV-irradiation and chemical mutagens in E. coli.

Journal: Mutation research 20010531

Title: High-performance liquid chromatography--ToxPrint: chromatographic analysis with a novel (geno)toxicity detection.

Journal: Journal of chromatography. A 20010525

Title: A p53 dose-response relationship for sensitivity to DNA damage in isogenic teratocarcinoma cells.

Journal: Oncogene 20010524

Title: Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20010501

Title: Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis.

Journal: Carcinogenesis 20010401

Title: Bloom helicase is involved in DNA surveillance in early S phase in vertebrate cells.

Journal: Oncogene 20010308

Title: Activation of Ty transposition by mutagens.

Journal: Mutation research 20010301

Title: Overexpression of JunB in undifferentiated malignant rat oral keratinocytes enhances the malignant phenotype in vitro without altering cellular differentiation.

Journal: International journal of cancer 20010301

Title: [Ultramicrostructural observation on epithelial cell disdifferentiation in rat tongue carcinogenesis induced by 4NQO].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology 20010301

Title: Increased expression of cyclooxygenase-2 protein in 4-nitroquinoline-1-oxide-induced rat tongue carcinomas and chemopreventive efficacy of a specific inhibitor, nimesulide.

Journal: Cancer research 20010215

Title: The effect of desalivation on 4-nitroquinoline-1-oxide-induced tongue carcinogenesis: a morphometric study of nucleolar organizer regions.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010101

Title: Antimutagenic activity of isoflavone from Pueraria lobata.

Journal: Journal of agricultural and food chemistry 20010101

Title: Identification of a phosphoprotein that is downregulated in immortalized human fibroblasts.

Journal: Electrophoresis 20010101

Title: Effect of caffeine on the genotoxic effects of gamma radiation and 4-NQO in diploid yeast.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101

Title: [Extracellular protein of propionic acid bacteria inhibits induced mutation in strains of Salmonella typhimurium].

Journal: Mikrobiologiia 20010101

Title: Roles of DT diaphorase in the genotoxicity of nitroaromatic compounds in human and fish cell lines.

Journal: Journal of toxicology and environmental health 19971010

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:56-57-5 Molecular Formula|56-57-5 MDL|56-57-5 SMILES|56-57-5 4-Nitroquinoline n-oxide |Heterocyclic_Building_Blocks |Organic_Building_Blocks