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5614-64-2,MFCD00039991
Catalog No.:AA00D7VN

5614-64-2 | 8-HYDROXYGUANINE

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Purity
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10mg
1 week  
$216.00   $151.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00D7VN
Chemical Name:
8-HYDROXYGUANINE
CAS Number:
5614-64-2
Molecular Formula:
C5H5N5O2
Molecular Weight:
167.1255
MDL Number:
MFCD00039991
SMILES:
NC1NC(=O)C2=NC(=NC2=N1)O
NSC Number:
22720
Properties
Computed Properties
 
Complexity:
342  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
4  
XLogP3:
-2.2  

Downstream Synthesis Route
902-04-5    73-40-5    5614-64-2    1186588-46-4    88847-89-6   
5'-monophosphate2'-deoxy-7,8-dihydro-8-oxo-guanosine 

[1]BioorganicandMedicinalChemistryLetters,2009,vol.19,p.4335-4338

961-07-9   
spiroiminodihydantoin-2'-deoxyribonucleoside 
  73-40-5    5614-64-2    1309569-79-6   
5-carboxamido-5-formamido-2-iminohydantion-2′-deoxyribonucleoside 
 
5',8-cyclo-2'-deoxyguanosine 
  88847-89-6   
N1-(β-D-erythro-pentofuranosyl)-5-guanidinohydantoin 

[1]JournalofOrganicChemistry,2015,vol.80,p.6996-7007

[2]JournalofOrganicChemistry,2015,vol.80,p.6996-7007

Literature

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Title: Action-at-a-distance mutagenesis induced by oxidized guanine in Werner syndrome protein-reduced human cells.

Journal: Chemical research in toxicology 20150420

Title: A functional Ser326Cys polymorphism in hOGG1 is associated with noise-induced hearing loss in a Chinese population.

Journal: PloS one 20140101

Title: Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea.

Journal: Mutagenesis 20121101

Title: DNA sequence context effects on the glycosylase activity of human 8-oxoguanine DNA glycosylase.

Journal: The Journal of biological chemistry 20121026

Title: Radiation-induced formation of 2',3'-dideoxyribonucleosides in DNA: a potential signature of low-energy electrons.

Journal: Journal of the American Chemical Society 20121024

Title: Lead(II)-catalyzed oxidation of guanine in solution studied with electrospray ionization mass spectrometry.

Journal: The journal of physical chemistry. B 20121004

Title: Profiling cytosine oxidation in DNA by LC-MS/MS.

Journal: Chemical research in toxicology 20120917

Title: Probing charge transport in oxidatively damaged DNA sequences under the influence of structural fluctuations.

Journal: The journal of physical chemistry. B 20120913

Title: Thermodynamic consequences of the hyperoxidized guanine lesion guanidinohydantoin in duplex DNA.

Journal: Chemical research in toxicology 20120820

Title: Mutagenic bypass of 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) by DNA polymerase κ in human cells.

Journal: Chemical research in toxicology 20120820

Title: Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation.

Journal: Environmental health perspectives 20120801

Title: Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1.

Journal: The Journal of biological chemistry 20120720

Title: The DNA glycosylases OGG1 and NEIL3 influence differentiation potential, proliferation, and senescence-associated signs in neural stem cells.

Journal: Biochemical and biophysical research communications 20120713

Title: Unzipping kinetics of duplex DNA containing oxidized lesions in an α-hemolysin nanopore.

Journal: Journal of the American Chemical Society 20120704

Title: Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair.

Journal: Molecular biology reports 20120701

Title: DNA damage induced by micro- and nanoparticles--interaction with FPG influences the detection of DNA oxidation in the comet assay.

Journal: Mutagenesis 20120701

Title: Formation of ring-opened and rearranged products of guanine: mechanisms and biological significance.

Journal: Free radical biology & medicine 20120701

Title: Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine.

Journal: The Journal of biological chemistry 20120615

Title: Distinct pattern of oxidative DNA damage and DNA repair in follicular thyroid tumours.

Journal: Journal of molecular endocrinology 20120601

Title: DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions.

Journal: Molecular and biochemical parasitology 20120601

Title: A DNA oligomer containing 2,2,4-triamino-5(2H)-oxazolone is incised by human NEIL1 and NTH1.

Journal: Mutation research 20120601

Title: Overexpression of AtOGG1, a DNA glycosylase/AP lyase, enhances seed longevity and abiotic stress tolerance in Arabidopsis.

Journal: Journal of experimental botany 20120601

Title: Greater nucleic acids oxidation in the temporal lobe than the frontal lobe in SAMP8.

Journal: Neuroreport 20120530

Title: Iron and genome stability: an update.

Journal: Mutation research 20120501

Title: Human 8-oxoguanine-DNA glycosylase-1 is downregulated in human basal cell carcinoma.

Journal: Molecular genetics and metabolism 20120501

Title: Recognition of damaged DNA: structure and dynamic markers.

Journal: Medicinal research reviews 20120501

Title: Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics.

Journal: Science (New York, N.Y.) 20120420

Title: DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis.

Journal: The Journal of biological chemistry 20120413

Title: Lowered nudix type 5 (NUDT5) expression leads to cell cycle retardation in HeLa cells.

Journal: Molecular and cellular biochemistry 20120401

Title: The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions.

Journal: Mutation research 20120401

Title: Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids.

Journal: Free radical research 20120401

Title: Age-dependent decline of DNA base excision repair activity in rat cortical neurons.

Journal: Mechanisms of ageing and development 20120401

Title: Urinary 8-oxoguanine as a predictor of survival in patients undergoing radiotherapy.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20120401

Title: Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem.

Journal: Cell cycle (Georgetown, Tex.) 20120315

Title: Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization.

Journal: Organic & biomolecular chemistry 20120307

Title: 8-Oxoguanine DNA glycosylase 1 (OGG1) from the copepod Tigriopus japonicus: molecular characterization and its expression in response to UV-B and heavy metals.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301

Title: Catalytic contributions of key residues in the adenine glycosylase MutY revealed by pH-dependent kinetics and cellular repair assays.

Journal: Chemistry & biology 20120224

Title: Direct analysis of 5-methylcytosine and 5-methyl-2'-deoxycytidine in human urine by isotope dilution LC-MS/MS: correlations with N-methylated purines and oxidized DNA lesions.

Journal: Chemical research in toxicology 20120220

Title: Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV.

Journal: Chemical research in toxicology 20120220

Title: Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base.

Journal: Free radical biology & medicine 20120215

Title: Urinary excretion of 8-oxo-7,8-dihydroguanine as biomarker of oxidative damage to DNA.

Journal: Archives of biochemistry and biophysics 20120215

Title: Copper oxide nanoparticle mediated DNA damage in terrestrial plant models.

Journal: Environmental science & technology 20120207

Title: 2-hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation.

Journal: Molecular biology reports 20120201

Title: DNA glycosylases: in DNA repair and beyond.

Journal: Chromosoma 20120201

Title: Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India.

Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120201

Title: Global analysis of RNA oxidation in Saccharomyces cerevisiae.

Journal: BioTechniques 20120201

Title: Interaction between the Cockayne syndrome B and p53 proteins: implications for aging.

Journal: Aging 20120201

Title: Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases.

Journal: Journal of the American Chemical Society 20120125

Title: Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling.

Journal: The Biochemical journal 20120115

Title: A DNA aptamer sensor for 8-oxo-7,8-dihydroguanine.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: Trinucleotide repeat DNA alters structure to minimize the thermodynamic impact of 8-oxo-7,8-dihydroguanine.

Journal: Biochemistry 20120110

Title: Oxidative stress, mitochondrial dysfunction, and aging.

Journal: Journal of signal transduction 20120101

Title: The specificity of UVA-induced DNA damage in human melanocytes.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120101

Title: 8-oxoguanine in a quadruplex of the human telomere DNA sequence.

Journal: The FEBS journal 20120101

Title: Influence of the OGG1 Ser326Cys polymorphism on oxidatively damaged DNA and repair activity.

Journal: Free radical biology & medicine 20120101

Title: Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study.

Journal: Free radical biology & medicine 20120101

Title: A new proofreading mechanism for lesion bypass by DNA polymerase-λ.

Journal: EMBO reports 20120101

Title: Mitochondria-ros crosstalk in the control of cell death and aging.

Journal: Journal of signal transduction 20120101

Title: Polychlorinated biphenyls-induced oxidative stress on rat hippocampus: a neuroprotective role of quercetin.

Journal: TheScientificWorldJournal 20120101

Title: Contribution of HOGG1 Ser³²⁶Cys polymorphism to the development of prostate cancer in smokers: meta-analysis of 2779 cases and 3484 controls.

Journal: PloS one 20120101

Title: Protein kinases and transcription factors activation in response to UV-radiation of skin: implications for carcinogenesis.

Journal: International journal of molecular sciences 20120101

Title: Effect of daily consumption of probiotic yogurt on oxidative stress in pregnant women: a randomized controlled clinical trial.

Journal: Annals of nutrition & metabolism 20120101

Title: Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China.

Journal: PloS one 20120101

Title: Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis.

Journal: Cell & bioscience 20120101

Title: Polymorphisms in base-excision & nucleotide-excision repair genes & prostate cancer risk in north Indian population.

Journal: The Indian journal of medical research 20120101

Title: DNA repair in human pluripotent stem cells is distinct from that in non-pluripotent human cells.

Journal: PloS one 20120101

Title: Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function.

Journal: Particle and fibre toxicology 20120101

Title: Overexpression of DNA polymerase zeta reduces the mitochondrial mutability caused by pathological mutations in DNA polymerase gamma in yeast.

Journal: PloS one 20120101

Title: Aberrant expression of N-methylpurine-DNA glycosylase influences patient survival in malignant gliomas.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Free radicals and extrinsic skin aging.

Journal: Dermatology research and practice 20120101

Title: The Escherichia coli SOS gene dinF protects against oxidative stress and bile salts.

Journal: PloS one 20120101

Title: The association between OGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis of 27 studies.

Journal: PloS one 20120101

Title: Molecular mechanisms for age-associated mitochondrial deficiency in skeletal muscle.

Journal: Journal of aging research 20120101

Title: Adult neurogenesis transiently generates oxidative stress.

Journal: PloS one 20120101

Title: Impact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosis.

Journal: PloS one 20120101

Title: [Generation of reactive oxygen species in water under exposure of visible or infrared irradiation at absorption band of molecular oxygen].

Journal: Biofizika 20120101

Title: Genetic aspects of gastric cancer instability.

Journal: TheScientificWorldJournal 20120101

Title: Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats.

Journal: PloS one 20120101

Title: Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson's Disease.

Journal: Frontiers in physiology 20120101

Title: Modulation of oxidative DNA damage by repair enzymes XRCC1 and hOGG1.

Journal: Journal of toxicology and environmental health. Part A 20120101

Title: Eckol inhibits ultraviolet B-induced cell damage in human keratinocytes via a decrease in oxidative stress.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers.

Journal: International journal of cell biology 20120101

Title: Association of base excision repair gene polymorphisms with ESRD risk in a Chinese population.

Journal: Oxidative medicine and cellular longevity 20120101

Title: 8-oxoguanine DNA glycosylases: one lesion, three subfamilies.

Journal: International journal of molecular sciences 20120101

Title: Association between environmental exposure to benzene and oxidative damage to nucleic acids in children.

Journal: La Medicina del lavoro 20120101

Title: Role of OGG1 Ser326Cys polymorphism and 8-oxoguanine DNA damage in risk assessment of squamous cell carcinoma of head and neck in North Indian population.

Journal: Mutation research 20111224

Title: Induction of DNA damage in human urothelial cells by the brominated flame retardant 2,2-bis(bromomethyl)-1,3-propanediol: role of oxidative stress.

Journal: Toxicology 20111218

Title: Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage.

Journal: Rejuvenation research 20111201

Title: Effects of DPP-4 inhibition on cardiac metabolism and function in mice.

Journal: Journal of molecular and cellular cardiology 20111201

Title: Increased expression of versican in the inflammatory response to UVB- and reactive oxygen species-induced skin tumorigenesis.

Journal: The American journal of pathology 20111201

Title: Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats.

Journal: Journal of toxicologic pathology 20111201

Title: Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells.

Journal: Toxicology letters 20111130

Title: Spectral characterization of guanine C4-OH adduct: a radiation and quantum chemical study.

Journal: The journal of physical chemistry. B 20111124

Title: Evidence for upregulated repair of oxidatively induced DNA damage in human colorectal cancer.

Journal: DNA repair 20111110

Title: 8-Hydroxyguanine: a base for discovery.

Journal: DNA repair 20111110

Title: Bisphenol A-glycidyl methacrylate induces a broad spectrum of DNA damage in human lymphocytes.

Journal: Archives of toxicology 20111101

Title: Nickel exposure induces oxidative damage to mitochondrial DNA in Neuro2a cells: the neuroprotective roles of melatonin.

Journal: Journal of pineal research 20111101

Title: Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer.

Journal: The Journal of pathology 20111101

Title: Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction.

Journal: American journal of physiology. Heart and circulatory physiology 20111101

Title: Oxidative stress in women with perimenopausal symptoms.

Journal: Menopause (New York, N.Y.) 20111101

Title: Utilizing G-quadruplex formation to target 8-oxoguanine in telomeric sequences.

Journal: Bioorganic & medicinal chemistry letters 20111101

Title: Siderite (FeCO₃) and magnetite (Fe₃O₄) overload-dependent pulmonary toxicity is determined by the poorly soluble particle not the iron content.

Journal: Inhalation toxicology 20111101

Title: [Mechanistic insight into hydrolysis of oxidized nucleotide diphosphates by human NUDT5].

Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20111101

Title: Chromium in drinking water: sources, metabolism, and cancer risks.

Journal: Chemical research in toxicology 20111017

Title: Hidden in plain sight: subtle effects of the 8-oxoguanine lesion on the structure, dynamics, and thermodynamics of a 15-base pair oligodeoxynucleotide duplex.

Journal: Biochemistry 20111004

Title: DNA replication and repair bypass machines.

Journal: Current opinion in chemical biology 20111001

Title: Nitrative and oxidative DNA damage caused by K-ras mutation in mice.

Journal: Biochemical and biophysical research communications 20110923

Title: Energetic preference of 8-oxoG eversion pathways in a DNA glycosylase.

Journal: Journal of the American Chemical Society 20110921

Title: Sequence-specific single-molecule analysis of 8-oxo-7,8-dihydroguanine lesions in DNA based on unzipping kinetics of complementary probes in ion channel recordings.

Journal: Journal of the American Chemical Society 20110921

Title: A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair.

Journal: Journal of the American Chemical Society 20110921

Title: New insights on the barrel medic MtOGG1 and MtFPG functions in relation to oxidative stress response in planta and during seed imbibition.

Journal: Plant physiology and biochemistry : PPB 20110901

Title: Mutagenicity of secondary oxidation products of 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'- deoxyguanosine 5'-triphosphate).

Journal: Mutation research 20110901

Title: Effect of sodium and acetate ions on 8-hydroxyguanine formation in irradiated aqueous solutions of DNA and 2'-deoxyguanosine 5'-monophosphate.

Journal: International journal of radiation biology 20110901

Title: Genetic and epigenetic alterations of lysophosphatidic Acid receptor genes in rodent tumors by experimental models.

Journal: Journal of toxicologic pathology 20110901

Title: First Steps Towards an Understanding of a Mode ofCarcinogenic Action for Vanadium Pentoxide.

Journal: Journal of toxicologic pathology 20110901

Title: Turn-on DNA damage sensors for the direct detection of 8-oxoguanine and photoproducts in native DNA.

Journal: Journal of the American Chemical Society 20110817

Title: Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion.

Journal: DNA repair 20110815

Title: Oxidative damage to RNA and expression patterns of MTH1 in the hippocampi of senescence-accelerated SAMP8 mice and Alzheimer's disease patients.

Journal: Neurochemical research 20110801

Title: Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain.

Journal: Mechanisms of ageing and development 20110801

Title: Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA.

Journal: Molecular aspects of medicine 20110801

Title: Computational study of the deamination of 8-oxoguanine.

Journal: The journal of physical chemistry. B 20110728

Title: Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide.

Journal: Chemical research in toxicology 20110718

Title: Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle.

Journal: Free radical biology & medicine 20110715

Title: Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.

Journal: Current pharmaceutical design 20110701

Title: Alcohol consumption and oxidative DNA damage.

Journal: International journal of environmental research and public health 20110701

Title: Rescue of the orphan enzyme isoguanine deaminase.

Journal: Biochemistry 20110628

Title: Delayed repair of radiation induced clustered DNA damage: friend or foe?

Journal: Mutation research 20110603

Title: hOGG1 Ser326Cys polymorphism and risk of childhood acute lymphoblastic leukemia in a Chinese population.

Journal: Cancer science 20110601

Title: Vitamin E ameliorates iodine-induced cytotoxicity in thyroid.

Journal: The Journal of endocrinology 20110601

Title: DNA polymerases provide a canon of strategies for translesion synthesis past oxidatively generated lesions.

Journal: Current opinion in structural biology 20110601

Title: Porphyromonas gingivalis mutY is involved in the repair of oxidative stress-induced DNA mispairing.

Journal: Molecular oral microbiology 20110601

Title: Association of gene polymorphisms with development of cancer risk or their protective role associated with some mutant alleles.

Journal: The Indian journal of medical research 20110601

Title: Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene human 8-oxoguanine DNA glycosylase (hOGG1) with the risk of squamous cell carcinomas of the head & neck (SCCHN) among north Indians.

Journal: The Indian journal of medical research 20110601

Title: 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes.

Journal: Mutation research 20110510

Title: The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells.

Journal: Free radical biology & medicine 20110501

Title: Seed imbibition in Medicago truncatula Gaertn.: Expression profiles of DNA repair genes in relation to PEG-mediated stress.

Journal: Journal of plant physiology 20110501

Title: First evidence for digenic inheritance in hereditary colorectal cancer by mutations in the base excision repair genes.

Journal: European journal of cancer (Oxford, England : 1990) 20110501

Title: 8-Hydroxyguanine levels and repair capacity during mouse embryonic stem cell differentiation.

Journal: Free radical research 20110501

Title: Oxidatively generated damage to DNA by UVA radiation in cells and human skin.

Journal: The Journal of investigative dermatology 20110501

Title: Cockayne syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo.

Journal: Aging 20110501

Title: The impact of OGG1, MTH1 and MnSOD gene polymorphisms on 8-hydroxy-2'-deoxyguanosine and cellular superoxide dismutase activity in myocardial ischemia-reperfusion.

Journal: Molecular biology reports 20110401

Title: In vitro functional effects of XPC gene rare variants from bladder cancer patients.

Journal: Carcinogenesis 20110401

Title: Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20110401

Title: The 8-oxoguanine DNA N-glycosylase 1 (hOGG1) Ser326Cys variant affects the susceptibility to Graves' disease.

Journal: Cell biochemistry and function 20110401

Title: Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

Journal: PLoS genetics 20110401

Title: Interactions between catalysts and amphiphilic structures and their implications for a protocell model.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20110314

Title: Early host cell reactivation of an oxidatively damaged adenovirus-encoded reporter gene requires the Cockayne syndrome proteins CSA and CSB.

Journal: Mutagenesis 20110301

Title: Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response.

Journal: Molecular and biochemical parasitology 20110301

Title: Mineralocorticoid receptor-mediated DNA damage in kidneys of DOCA-salt hypertensive rats.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110301

Title: Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers.

Journal: Cancer research 20110301

Title: Combined toxic exposures and human health: biomarkers of exposure and effect.

Journal: International journal of environmental research and public health 20110301

Title: DNA damage and repair in endometrial cancer in correlation with the hOGG1 and RAD51 genes polymorphism.

Journal: Molecular biology reports 20110201

Title: Aldosterone induces oxidative stress, oxidative DNA damage and NF-κB-activation in kidney tubule cells.

Journal: Molecular carcinogenesis 20110201

Title: Oxidative DNA damage bypass in Arabidopsis thaliana requires DNA polymerase λ and proliferating cell nuclear antigen 2.

Journal: The Plant cell 20110201

Title: Reference ranges of urinary biomarkers of oxidized guanine in (2'-deoxy)ribonucleotides and nucleic acids.

Journal: Free radical biology & medicine 20110115

Title: 8-Oxoguanine DNA-glycosylase repair activity and expression: a comparison between cryopreserved isolated lymphocytes and EBV-derived lymphoblastoid cell lines.

Journal: Mutation research 20110110

Title: Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol.

Journal: Carcinogenesis 20110101

Title: Quantitative assessment of DNA damage directly in lens epithelial cells from senile cataract patients.

Journal: Molecular vision 20110101

Title: Gallbladder cancer predisposition: a multigenic approach to DNA-repair, apoptotic and inflammatory pathway genes.

Journal: PloS one 20110101

Title: Mysterious link between iron overload and CDKN2A/2B.

Journal: Journal of clinical biochemistry and nutrition 20110101

Title: Phytic Acid Protects against 6-Hydroxydopamine-Induced Dopaminergic Neuron Apoptosis in Normal and Iron Excess Conditions in a Cell Culture Model.

Journal: Parkinson's disease 20110101

Title: Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium.

Journal: BMC microbiology 20110101

Title: Mitochondrial DNA damage and animal longevity: insights from comparative studies.

Journal: Journal of aging research 20110101

Title: The base excision repair pathway is required for efficient lentivirus integration.

Journal: PloS one 20110101

Title: Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers.

Journal: BMC public health 20110101

Title: Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews 20110101

Title: Inactivation of the DNA repair genes mutS, mutL or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes.

Journal: PloS one 20110101

Title: Dose-dependent onset of regenerative program in neutron irradiated mouse skin.

Journal: PloS one 20110101

Title: Metabolism, genomics, and DNA repair in the mouse aging liver.

Journal: Current gerontology and geriatrics research 20110101

Title: NNK-Induced Lung Tumors: A Review of Animal Model.

Journal: Journal of oncology 20110101

Title: Salivary 8-OHdG Induction by Physical Exercise Training Under Food Restriction.

Journal: The open dentistry journal 20110101

Title: Mechanism of recognition and repair of damaged DNA by human 8-oxoguanine DNA glycosylase hOGG1.

Journal: Biochemistry. Biokhimiia 20110101

Title: Reduction in oxidatively generated DNA damage following smoking cessation.

Journal: Tobacco induced diseases 20110101

Title: Oxidative damage DNA: 8-oxoGua and 8-oxodG as molecular markers of cancer.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20110101

Title: Assessment of the genetic risks of a metallic alloy used in medical implants.

Journal: Genetics and molecular biology 20110101

Title: Synchronization of cytoplasmic and transferred mitochondrial ribosomal protein gene expression in land plants is linked to Telo-box motif enrichment.

Journal: BMC evolutionary biology 20110101

Title: Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans.

Journal: PloS one 20110101

Title: Therapeutic effects of hydrogen in animal models of Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: Adenylate kinase 3 sensitizes cells to cigarette smoke condensate vapor induced cisplatin resistance.

Journal: PloS one 20110101

Title: Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease.

Journal: Alzheimer's research & therapy 20110101

Title: Alterations in DNA repair gene expression and their possible regulation in rat-liver regeneration.

Journal: Genetics and molecular biology 20110101

Title: Is the GSTM1 null polymorphism a risk factor in primary open angle glaucoma?

Journal: Molecular vision 20110101

Title: Ribosomal protein s3: a multifunctional target of attaching/effacing bacterial pathogens.

Journal: Frontiers in microbiology 20110101

Title: Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

Journal: Clinical and experimental gastroenterology 20110101

Title: Oxidative DNA Damage in Blood of CVD Patients Taking Detralex.

Journal: The open cardiovascular medicine journal 20110101

Title: The hOGG1 Ser326Cys polymorphism and prostate cancer risk: a meta-analysis of 2584 cases and 3234 controls.

Journal: BMC cancer 20110101

Title: RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease.

Journal: PloS one 20110101

Title: Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1.

Journal: International journal of hepatology 20110101

Title: Characterization of a Mycobacterium smegmatis uvrA mutant impaired in dormancy induced by hypoxia and low carbon concentration.

Journal: BMC microbiology 20110101

Title: Pharmaceutical and nutraceutical effects of Pinus pinaster bark extract.

Journal: Research in pharmaceutical sciences 20110101

Title: Anti-inflammatory drugs reduce the risk of hepatocellular carcinoma development.

Journal: ISRN oncology 20110101

Title: The effect of hOGG1 Ser326Cys polymorphism on cancer risk: evidence from a meta-analysis.

Journal: PloS one 20110101

Title: Biological sensors for solar ultraviolet radiation.

Journal: Sensors (Basel, Switzerland) 20110101

Title: Visible light may directly induce nuclear DNA damage triggering the death pathway in RGC-5 cells.

Journal: Molecular vision 20110101

Title: Earthworms and soil pollutants.

Journal: Sensors (Basel, Switzerland) 20110101

Title: Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers.

Journal: International journal of molecular sciences 20110101

Title: Nanopore detection of 8-oxo-7,8-dihydro-2'-deoxyguanosine in immobilized single-stranded DNA via adduct formation to the DNA damage site.

Journal: Journal of the American Chemical Society 20101229

Title: Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress.

Journal: Biochemical and biophysical research communications 20101210

Title: Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase.

Journal: Mutation research 20101128

Title: DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine.

Journal: Mutation research 20101128

Title: Salvage of oxidized guanine derivatives in the (2'-deoxy)ribonucleotide pool as source of mutations in DNA.

Journal: Mutation research 20101128

Title: The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals.

Journal: The Biochemical journal 20101115

Title: Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase η.

Journal: Structure (London, England : 1993) 20101110

Title: Non-additive interactions of nucleobases in model dinucleotide steps occurring in B-DNA crystals.

Journal: Journal of molecular modeling 20101101

Title: Impact of histone deacetylase inhibitors SAHA and MS-275 on DNA repair pathways in human mesenchymal stem cells.

Journal: Journal of cellular physiology 20101101

Title: Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.

Journal: Human mutation 20101101

Title: Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples.

Journal: Archives of toxicology 20101101

Title: Asian dust and titanium dioxide particles-induced inflammation and oxidative DNA damage in C57BL/6 mice.

Journal: Inhalation toxicology 20101101

Title: Sensitive voltammetric sensor for the determination of oxidative DNA damage in calf thymus DNA.

Journal: Biosensors & bioelectronics 20101015

Title: Photosensitization induced by the antibacterial fluoroquinolone Rufloxacin leads to mutagenesis in yeast.

Journal: Mutation research 20101013

Title: Mechanism of genotoxicity induced by targeted cytoplasmic irradiation.

Journal: British journal of cancer 20101012

Title: Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG): a mismatch recognition.

Journal: DNA repair 20101005

Title: Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP and dGMP to be inserted opposite Guanidinohydantoin .

Journal: Biochemistry 20101005

Title: regT can modulate gingipain activity and response to oxidative stress in Porphyromonas gingivalis.

Journal: Microbiology (Reading, England) 20101001

Title: Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.

Journal: Acta neuropathologica 20101001

Title: Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20101001

Title: Genomic damage in endstage renal disease-contribution of uremic toxins.

Journal: Toxins 20101001

Title: UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test.

Journal: Mutation research 20100910

Title: Epithelial ablation of Bcl-XL increases sensitivity to oxygen without disrupting lung development.

Journal: American journal of respiratory cell and molecular biology 20100901

Title: Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients.

Journal: Mutagenesis 20100901

Title: Genome-scale approaches to investigate oxidative DNA damage.

Journal: Journal of clinical biochemistry and nutrition 20100901

Title: 8-Oxo-7,8-dihydroguanine: links to gene expression, aging, and defense against oxidative stress.

Journal: Free radical biology & medicine 20100815

Title: Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution.

Journal: Environmental health perspectives 20100801

Title: Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase in the presence of replication protein A and proliferating-cell nuclear antigen.

Journal: The Biochemical journal 20100801

Title: Saccharomyces cerevisiae-based system for studying clustered DNA damages.

Journal: Radiation and environmental biophysics 20100801

Title: Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100701

Title: Role of vimA in cell surface biogenesis in Porphyromonas gingivalis.

Journal: Microbiology (Reading, England) 20100701

Title: Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage.

Journal: Diabetes 20100701

Title: The tyrosyl-DNA phosphodiesterase gene family in Medicago truncatula Gaertn.: bioinformatic investigation and expression profiles in response to copper- and PEG-mediated stress.

Journal: Planta 20100701

Title: Dynamic flexibility of DNA repair pathways in growth arrested Escherichia coli.

Journal: DNA repair 20100701

Title: Detection of damaged DNA bases by DNA glycosylase enzymes.

Journal: Biochemistry 20100622

Title: The oxidation of 8-oxo-7,8-dihydroguanine by iodine.

Journal: Bioorganic & medicinal chemistry letters 20100615

Title: Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine.

Journal: DNA repair 20100604

Title: Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.

Journal: DNA repair 20100604

Title: Electrochemical oxidation of guanine: electrode reaction mechanism and tailoring carbon electrode surfaces to switch between adsorptive and diffusional responses.

Journal: The journal of physical chemistry. B 20100603

Title: Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes.

Journal: Environmental health perspectives 20100601

Title: Biomarkers of lead exposure and DNA methylation within retrotransposons.

Journal: Environmental health perspectives 20100601

Title: Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: evidence for oxidatively DNA damage generation.

Journal: Mutation research 20100601

Title: Measurement of oxidatively generated base damage in cellular DNA and urine.

Journal: Free radical biology & medicine 20100601

Title: Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits.

Journal: Birth defects research. Part C, Embryo today : reviews 20100601

Title: Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .

Journal: Biochemistry 20100518

Title: Oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine by oxyl radicals produced by photolysis of azo compounds.

Journal: Chemical research in toxicology 20100517

Title: Aging and oxidatively damaged nuclear DNA in animal organs.

Journal: Free radical biology & medicine 20100515

Title: Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine.

Journal: DNA repair 20100504

Title: Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100501

Title: A MATE-family efflux pump rescues the Escherichia coli 8-oxoguanine-repair-deficient mutator phenotype and protects against H(2)O(2) killing.

Journal: PLoS genetics 20100501

Title: Characterization of oxidative guanine damage and repair in mammalian telomeres.

Journal: PLoS genetics 20100501

Title: Effects of valproate, carbamazepine, and levetiracetam on the antioxidant and oxidant systems in epileptic patients and their clinical importance.

Journal: Clinical neuropharmacology 20100501

Title: Molecular dynamics simulation of 8-oxoguanine containing DNA fragments reveals altered hydration and ion binding patterns.

Journal: The journal of physical chemistry. B 20100415

Title: Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes.

Journal: The Journal of biological chemistry 20100409

Title: SECIS-binding protein 2 promotes cell survival by protecting against oxidative stress.

Journal: Antioxidants & redox signaling 20100401

Title: OGG1 is a novel prognostic indicator in acute myeloid leukaemia.

Journal: Oncogene 20100401

Title: Octyl methoxycinnamate modulates gene expression and prevents cyclobutane pyrimidine dimer formation but not oxidative DNA damage in UV-exposed human cell lines.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100401

Title: Occupational exposure to low levels of benzene: Biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes.

Journal: Toxicology letters 20100401

Title: Roles of specialized DNA polymerases in mutagenesis by 8-hydroxyguanine in human cells.

Journal: Mutation research 20100401

Title: [The influence of oxidized DNA on mammalian genome].

Journal: Fukuoka igaku zasshi = Hukuoka acta medica 20100401

Title: Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69.

Journal: Biochemistry 20100323

Title: Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin.

Journal: Biochemistry 20100323

Title: The C-terminal lysine of Ogg2 DNA glycosylases is a major molecular determinant for guanine/8-oxoguanine distinction.

Journal: Journal of molecular biology 20100319

Title: Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients.

Journal: Radiation and environmental biophysics 20100301

Title: An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay.

Journal: Mutagenesis 20100301

Title: Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.

Journal: Nucleic acids research 20100301

Title: Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.

Journal: Cancer research 20100301

Title: A two-tiered compensatory response to loss of DNA repair modulates aging and stress response pathways.

Journal: Aging 20100301

Title: The hunt for 8-oxoguanine deaminase.

Journal: Journal of the American Chemical Society 20100217

Title: Oxidation of DNA: damage to nucleobases.

Journal: Accounts of chemical research 20100216

Title: Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosines.

Journal: Biochemistry 20100216

Title: Influence of substrate complexity on the diastereoselective formation of spiroiminodihydantoin and guanidinohydantoin from chromate oxidation.

Journal: Chemical research in toxicology 20100215

Title: The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate preferences from their Escherichia coli counterparts.

Journal: DNA repair 20100204

Title: Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells.

Journal: DNA repair 20100204

Title: MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.

Journal: Human mutation 20100201

Title: Metallothionein-I + II and receptor megalin are altered in relation to oxidative stress in cerebral lymphomas.

Journal: Leukemia & lymphoma 20100201

Title: Novel molecular insights into the mechanism of GO removal by MutM.

Journal: Cell research 20100201

Title: Exposure to 1800 MHz radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons.

Journal: Brain research 20100122

Title: Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast.

Journal: The EMBO journal 20100120

Title: A liquid chromatography-mass spectrometric assay for measuring activity of human 8-oxoguanine-DNA glycosylase.

Journal: Analytical biochemistry 20100115

Title: Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM.

Journal: The Journal of biological chemistry 20100108

Title: Effects of cryopreservation on human sperm deoxyribonucleic acid integrity.

Journal: Fertility and sterility 20100101

Title: Simultaneous determination in situ of DNA fragmentation and 8-oxoguanine in human sperm.

Journal: Fertility and sterility 20100101

Title: A distinct physiological role of MutY in mutation prevention in mycobacteria.

Journal: Microbiology (Reading, England) 20100101

Title: Urinary analysis of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction: Study of 8-oxo-7,8-dihydroguanine stability.

Journal: Free radical biology & medicine 20100101

Title: Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base.

Journal: The Journal of biological chemistry 20100101

Title: Exposure assessment of PM2.5 and urinary 8-OHdG for diesel exhaust emission inspector.

Journal: The Science of the total environment 20100101

Title: The effect of oxidative stress on nucleotide-excision repair in colon tissue of newborn piglets.

Journal: Mutation research 20100101

Title: Analysis of the contribution of charge transport in iodine-125-induced DNA damage.

Journal: Radiation research 20100101

Title: Effect of quadruplex conformation on radiation-induced formation of 8-hydroxyguanine and unaltered base release in polyguanylic acid.

Journal: Radiation research 20100101

Title: Folate deficiency alters hepatic and colon MGMT and OGG-1 DNA repair protein expression in rats but has no effect on genome-wide DNA methylation.

Journal: Cancer prevention research (Philadelphia, Pa.) 20100101

Title: Endonuclease IV is the main base excision repair enzyme involved in DNA damage induced by UVA radiation and stannous chloride.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Selenoprotein P controls oxidative stress in cornea.

Journal: PloS one 20100101

Title: Adenine oxidation by pyrite-generated hydroxyl radicals.

Journal: Geochemical transactions 20100101

Title: Long-term progestin contraceptives (LTPOC) induce aberrant angiogenesis, oxidative stress and apoptosis in the guinea pig uterus: A model for abnormal uterine bleeding in humans.

Journal: Journal of angiogenesis research 20100101

Title: Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy.

Journal: PloS one 20100101

Title: Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors.

Journal: Frontiers in aging neuroscience 20100101

Title: XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium.

Journal: Molecular vision 20100101

Title: Oxidative stress and DNA methylation in prostate cancer.

Journal: Obstetrics and gynecology international 20100101

Title: The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.

Journal: PloS one 20100101

Title: Redox regulation in cancer: a double-edged sword with therapeutic potential.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers.

Journal: BMC cancer 20100101

Title: Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV.

Journal: Journal of nucleic acids 20100101

Title: Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta.

Journal: Journal of nucleic acids 20100101

Title: Evolutionary loss of 8-oxo-G repair components among eukaryotes.

Journal: Genome integrity 20100101

Title: New evidence on iron, copper accumulation and zinc depletion and its correlation with DNA integrity in aging human brain regions.

Journal: Indian journal of psychiatry 20100101

Title: A study of association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Age-associated modifications of Base Excision Repair activities in human skin fibroblast extracts.

Journal: Mechanisms of ageing and development 20100101

Title: Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage.

Journal: Journal of nucleic acids 20100101

Title: Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant.

Journal: Journal of nucleic acids 20100101

Title: Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe.

Journal: Journal of nucleic acids 20100101

Title: Characterization of a Y-Family DNA Polymerase eta from the Eukaryotic Thermophile Alvinella pompejana.

Journal: Journal of nucleic acids 20100101

Title: Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies.

Journal: Journal of nucleic acids 20100101

Title: Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine.

Journal: Journal of nucleic acids 20100101

Title: Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major.

Journal: Journal of nucleic acids 20100101

Title: Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems.

Journal: Journal of nucleic acids 20100101

Title: Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis.

Journal: Journal of nucleic acids 20100101

Title: Cu,Zn-superoxide dismutase deficiency in mice leads to organ-specific increase in oxidatively damaged DNA and NF-κB1 protein activity.

Journal: Acta biochimica Polonica 20100101

Title: The ERCC6 gene and age-related macular degeneration.

Journal: PloS one 20100101

Title: 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: α-Synuclein and DJ-1 as potential biological fluid biomarkers for Parkinson's Disease.

Journal: International journal of molecular sciences 20100101

Title: Evidence of altered DNA integrity in the brain regions of suicidal victims of Bipolar Depression.

Journal: Indian journal of psychiatry 20100101

Title: How does pycnogenol® influence oxidative damage to DNA and its repair ability in elderly people?

Journal: Prague medical report 20100101

Title: Kinetic approaches to understanding the mechanisms of fidelity of the herpes simplex virus type 1 DNA polymerase.

Journal: Journal of nucleic acids 20100101

Title: Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair.

Journal: Journal of nucleic acids 20100101

Title: The biological and metabolic fates of endogenous DNA damage products.

Journal: Journal of nucleic acids 20100101

Title: What can surrogate tissues tell us about the oxidative stress status of the prostate? A hypothesis-generating in-vivo study.

Journal: PloS one 20100101

Title: Genotoxic effect induced by hydrogen peroxide in human hepatoma cells using comet assay.

Journal: The Libyan journal of medicine 20100101

Title: Non-homologous DNA end joining in normal and cancer cells and its dependence on break structures.

Journal: Genetics and molecular biology 20100101

Title: Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses.

Journal: Journal of pharmacy & bioallied sciences 20100101

Title: Analysis of an anomalous mutant of MutM DNA glycosylase leads to new insights into the catalytic mechanism.

Journal: Journal of the American Chemical Society 20091230

Title: Solvent effects on ionization potentials of guanine runs and chemically modified guanine in duplex DNA: effect of electrostatic interaction and its reduction due to solvent.

Journal: The journal of physical chemistry. B 20091224

Title: Age-related alterations in the expression of MTH2 in the hippocampus of the SAMP8 mouse with learning and memory deterioration.

Journal: Journal of the neurological sciences 20091215

Title: Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme.

Journal: Nature 20091210

Title: Reversible chemical step and rate-limiting enzyme regeneration in the reaction catalyzed by formamidopyrimidine-DNA glycosylase.

Journal: Biochemistry 20091208

Title: Apex1 can cleave complex clustered DNA lesions in cells.

Journal: DNA repair 20091203

Title: alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes.

Journal: Pigment cell & melanoma research 20091201

Title: Effects of 7,8-dihydro-8-oxo-deoxyguanosine on antigen challenge in ovalbumin-sensitized mice may be mediated by suppression of Rac.

Journal: British journal of pharmacology 20091201

Title: hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type.

Journal: Journal of human genetics 20091201

Title: Do mtDNA Mutations Participate in the Pathogenesis of Sporadic Parkinson's Disease?

Journal: Current genomics 20091201

Title: No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats.

Journal: Journal of toxicologic pathology 20091201

Title: Molecular basis of transcriptional mutagenesis at 8-oxoguanine.

Journal: The Journal of biological chemistry 20091113

Title: Comparison of isoelectronic 8-HO-G and 8-NH2-G derivatives in redox processes.

Journal: Journal of the American Chemical Society 20091104

Title: Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase.

Journal: DNA repair 20091102

Title: Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice.

Journal: Pediatric research 20091101

Title: Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine.

Journal: Journal of clinical biochemistry and nutrition 20091101

Title: Stochastic drift in mitochondrial DNA point mutations: a novel perspective ex silico.

Journal: PLoS computational biology 20091101

Title: Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells.

Journal: Free radical biology & medicine 20091015

Title: Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis.

Journal: Free radical biology & medicine 20091015

Title: Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion.

Journal: The Journal of biological chemistry 20091009

Title: Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers.

Journal: Toxicology letters 20091008

Title: Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.

Journal: Mutation research 20091002

Title: Repair activities of human 8-oxoguanine DNA glycosylase are stimulated by the interaction with human checkpoint sensor Rad9-Rad1-Hus1 complex.

Journal: DNA repair 20091002

Title: Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain.

Journal: DNA repair 20091002

Title: Chronic alcohol consumption prevents 8-hydroxyguanine accumulation in 3'-methyl-4-dimethylaminoazobenzene-treated mouse liver.

Journal: Biochemical and biophysical research communications 20090918

Title: Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo.

Journal: Free radical biology & medicine 20090915

Title: Direct and indirect roles of RECQL4 in modulating base excision repair capacity.

Journal: Human molecular genetics 20090915

Title: Modulation of DNA glycosylase activities in mesenchymal stem cells.

Journal: Experimental cell research 20090910

Title: Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides.

Journal: Biochemistry 20090901

Title: Formation of spiroiminodihydantoin nucleoside from 8-oxo-7,8-dihydro-2'-deoxyguanosine by nitric oxide under aerobic conditions.

Journal: Bioorganic & medicinal chemistry letters 20090901

Title: Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase.

Journal: The FEBS journal 20090901

Title: Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.

Journal: Biochemistry 20090804

Title: A study of pyrimidine base damage in relation to oxidative stress and cancer.

Journal: British journal of cancer 20090804

Title: Investigation of effects of Lacidipine, Ramipril and Valsartan on DNA damage and oxidative stress occurred in acute and chronic periods following isoproterenol-induced myocardial infarct in rats.

Journal: Molecular and cellular biochemistry 20090801

Title: Blackcurrant seed press residue increases tocopherol concentrations in serum and stool whilst biomarkers in stool and urine indicate increased oxidative stress in human subjects.

Journal: The British journal of nutrition 20090801

Title: Structure-dependent DNA damage and repair in a trinucleotide repeat sequence.

Journal: Biochemistry 20090721

Title: Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array.

Journal: British journal of cancer 20090721

Title: African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA.

Journal: Virology 20090720

Title: Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA.

Journal: DNA repair 20090704

Title: Mutational studies of Pa-AGOG DNA glycosylase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.

Journal: DNA repair 20090704

Title: FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.

Journal: The Journal of biological chemistry 20090703

Title: Electrostatic potential maps of damaged DNA studied by image analysis tools. 8-Oxoguanine and abasic site lesions.

Journal: Journal of molecular modeling 20090701

Title: Impact of radiotherapy and chemotherapy on biomarkers of oxidative DNA damage in lung cancer patients.

Journal: Clinical biochemistry 20090701

Title: Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma.

Journal: Carcinogenesis 20090701

Title: Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy.

Journal: Free radical research 20090701

Title: Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.

Journal: Nucleic acids research 20090701

Title: Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats.

Journal: FEMS immunology and medical microbiology 20090701

Title: Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090701

Title: Origin of an alternative genetic code in the extremely small and GC-rich genome of a bacterial symbiont.

Journal: PLoS genetics 20090701

Title: Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells.

Journal: PLoS genetics 20090701

Title: DNA repair efficiency in transgenic mice over expressing ribosomal protein S3.

Journal: Mutation research 20090618

Title: Up-regulation of myocardial DNA base excision repair activities in experimental heart failure.

Journal: Mutation research 20090618

Title: Glutathione depletion by buthionine sulfoximine induces oxidative damage to DNA in organs of rabbits in vivo.

Journal: Biochemistry 20090609

Title: Structural and energetic heterogeneities of canonical and oxidized central guanine triad of B-DNA telomeric fragments.

Journal: Journal of molecular modeling 20090601

Title: Absolute configurations of spiroiminodihydantoin and allantoin stereoisomers: comparison of computed and measured electronic circular dichroism spectra.

Journal: Chemical research in toxicology 20090601

Title: Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress.

Journal: Chemical research in toxicology 20090518

Title: Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis.

Journal: Cancer research 20090515

Title: Flexibility promotes fidelity.

Journal: Structure (London, England : 1993) 20090513

Title: Crystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction.

Journal: Structure (London, England : 1993) 20090513

Title: Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.

Journal: Structure (London, England : 1993) 20090513

Title: Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases.

Journal: DNA repair 20090501

Title: Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.

Journal: Free radical biology & medicine 20090501

Title: Serendipitous findings while researching oxygen free radicals.

Journal: Free radical biology & medicine 20090415

Title: Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase.

Journal: The Journal of biological chemistry 20090403

Title: Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress.

Journal: The Biochemical journal 20090401

Title: TEGDMA-induced oxidative DNA damage and activation of ATM and MAP kinases.

Journal: Biomaterials 20090401

Title: Enhancement of lung carcinogenesis initiated with 4-(N-hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone by Ogg1 gene deficiency in female, but not male, mice.

Journal: The Journal of toxicological sciences 20090401

Title: DNA oxidation: investigating its key role in environmental mutagenesis with the comet assay.

Journal: Mutation research 20090331

Title: Polynucleotide phosphorylase protects Escherichia coli against oxidative stress.

Journal: Biochemistry 20090310

Title: An emissive C analog distinguishes between G, 8-oxoG, and T.

Journal: Organic letters 20090305

Title: Toward a molecular equivalent dose: use of the medaka model in comparative risk assessment.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090301

Title: Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in Saccharomyces cerevisiae.

Journal: DNA repair 20090301

Title: 8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein.

Journal: DNA repair 20090301

Title: The DNA repair protein NBS1 influences the base excision repair pathway.

Journal: Carcinogenesis 20090301

Title: The oxidative stress response is region specific in organogenesis stage mouse embryos exposed to 5-bromo-2'-deoxyuridine.

Journal: Birth defects research. Part A, Clinical and molecular teratology 20090301

Title: In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine.

Journal: Chemical research in toxicology 20090301

Title: Polymorphisms of the DNA base excision repair gene MUTYH in head and neck cancer.

Journal: Experimental oncology 20090301

Title: Oxidative stress biomarkers and lifestyles in Japanese healthy people.

Journal: Journal of clinical biochemistry and nutrition 20090301

Title: Activated toxicity of diesel particulate extract by ultraviolet a radiation in mammalian cells: role of singlet oxygen.

Journal: Environmental health perspectives 20090301

Title: Targeting the progression of Parkinson's disease.

Journal: Current neuropharmacology 20090301

Title: Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice.

Journal: Aging 20090301

Title: Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains.

Journal: Journal of toxicologic pathology 20090301

Title: Impact of 7,8-dihydro-8-oxoguanine on methylation of the CpG site by Dnmt3a.

Journal: Biochemistry 20090217

Title: The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells.

Journal: Carcinogenesis 20090201

Title: Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one.

Journal: Biochemistry 20090120

Title: UV-inducible base excision repair of oxidative damaged DNA in human cells.

Journal: Mutagenesis 20090101

Title: Base excision repair of oxidative DNA damage and association with cancer and aging.

Journal: Carcinogenesis 20090101

Title: Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N-glycosylases.

Journal: Biochimica et biophysica acta 20090101

Title: DNA polymerase kappa from Trypanosoma cruzi localizes to the mitochondria, bypasses 8-oxoguanine lesions and performs DNA synthesis in a recombination intermediate.

Journal: Molecular microbiology 20090101

Title: Postmortem miscoding lesions in sequence analysis of human ancient mitochondrial DNA.

Journal: Journal of molecular evolution 20090101

Title: Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Journal: BMC medical genomics 20090101

Title: Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair.

Journal: BMC microbiology 20090101

Title: Acute exercise and oxidative stress: a 30 year history.

Journal: Dynamic medicine : DM 20090101

Title: Requirement for abasic endonuclease gene homologues in Arabidopsis seed development.

Journal: PloS one 20090101

Title: 8-Oxo-7,8-dihydro-2'-deoxyguanosine Forms a Relatively Unstable Tetrameric Structure Compared with 2'-Deoxyguanosine.

Journal: Journal of clinical biochemistry and nutrition 20090101

Title: ATM localization and gene expression in the adult mouse eye.

Journal: Molecular vision 20090101

Title: Alveolar epithelial and endothelial cell apoptosis in emphysema: what we know and what we need to know.

Journal: International journal of chronic obstructive pulmonary disease 20090101

Title: Apoptosis and telomeres shortening related to HIV-1 induced oxidative stress in an astrocytoma cell line.

Journal: BMC neuroscience 20090101

Title: Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion.

Journal: PloS one 20090101

Title: Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina.

Journal: Molecular vision 20090101

Title: Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Construction and characterization of a cell line deficient in repair of mitochondrial, but not nuclear, oxidative DNA damage.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity.

Journal: BMC biochemistry 20090101

Title: Molecular analysis of the APC and MUTYH genes in Galician and Catalonian FAP families: a different spectrum of mutations?

Journal: BMC medical genetics 20090101

Title: DNA damage induces nuclear translocation of parkin.

Journal: Journal of biomedical science 20090101

Title: Mutation analysis of Rad18 in human cancer cell lines and non small cell lung cancer tissues.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Genotoxicity of nano/microparticles in in vitro micronuclei, in vivo comet and mutation assay systems.

Journal: Particle and fibre toxicology 20090101

Title: One-electron oxidation of DNA: mechanism and consequences.

Journal: Nucleic acids symposium series (2004) 20090101

Title: Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance.

Journal: Molecular neurodegeneration 20090101

Title: Familial adenomatous polyposis.

Journal: Orphanet journal of rare diseases 20090101

Title: Endogenous melatonin and oxidatively damaged guanine in DNA.

Journal: BMC endocrine disorders 20090101

Title: DNA damage/repair and polymorphism of the hOGG1 gene in lymphocytes of AMD patients.

Journal: Journal of biomedicine & biotechnology 20090101

Title: Effect of hyperoxidized guanine on DNA primer-template structures: spiroiminodihydantoin leads to strand slippage.

Journal: FEBS letters 20081224

Title: Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects.

Journal: Free radical biology & medicine 20081215

Title: The association of OGG1 Ser326Cys polymorphism and urinary 8-OHdG levels with lung cancer susceptibility: a hospital-based case-control study in Turkey.

Journal: Arhiv za higijenu rada i toksikologiju 20081201

Title: Angiotensin II induces DNA damage in the kidney.

Journal: Cancer research 20081115

Title: Deficient repair of 8-hydroxyguanine in the BxPC-3 pancreatic cancer cell line.

Journal: Biochemical and biophysical research communications 20081114

Title: Influence of neighbouring base sequences on the mutagenesis induced by 7,8-dihydro-8-oxoguanine in yeast.

Journal: Mutagenesis 20081101

Title: Enhancement of apoptotic damage of squamous cell carcinoma cells by inhibition of the mitochondrial DNA repairing system.

Journal: Cancer science 20081101

Title: A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration.

Journal: PLoS genetics 20081101

Title: Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism.

Journal: International journal of cancer 20081015

Title: Effects of the bacterial transcription-repair coupling factor during transcription of DNA containing non-bulky lesions.

Journal: DNA repair 20081001

Title: Extremely low frequency magnetic fields cause oxidative DNA damage in rats.

Journal: International journal of radiation biology 20081001

Title: The tumor suppressor homolog in fission yeast, myh1(+), displays a strong interaction with the checkpoint gene rad1(+).

Journal: Mutation research 20080926

Title: Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080903

Title: MUTYH Associated Polyposis (MAP).

Journal: Current genomics 20080901

Title: Lipoic acid rescues DBA mice from early-onset age-related hearing impairment.

Journal: Neuroreport 20080827

Title: Correlated cleavage of damaged DNA by bacterial and human 8-oxoguanine-DNA glycosylases.

Journal: Biochemistry 20080826

Title: Interplay of two major repair pathways in the processing of complex double-strand DNA breaks.

Journal: DNA repair 20080802

Title: Carcinogenic risk of copper gluconate evaluated by a rat medium-term liver carcinogenicity bioassay protocol.

Journal: Archives of toxicology 20080801

Title: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases.

Journal: The FEBS journal 20080801

Title: SPR imaging for label-free multiplexed analyses of DNA N-glycosylase interactions with damaged DNA duplexes.

Journal: The Analyst 20080801

Title: Repair system of 7, 8-dihydro-8-oxoguanine as a defense line against carcinogenesis.

Journal: Journal of radiation research 20080701

Title: Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine.

Journal: Environmental and molecular mutagenesis 20080601

Title: Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells.

Journal: DNA repair 20080601

Title: DNA polymerases and oxidative damage: friends or foes?

Journal: Current molecular pharmacology 20080601

Title: Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus.

Journal: Proteins 20080515

Title: Lesion processing: high-fidelity versus lesion-bypass DNA polymerases.

Journal: Trends in biochemical sciences 20080501

Title: Antioxidant vitamins and cancer risk: is oxidative damage to DNA a relevant biomarker?

Journal: European journal of nutrition 20080501

Title: Catalytic involvement of CO2 in the mutagenesis caused by reactions of ONOO(-) with guanine.

Journal: The journal of physical chemistry. B 20080417

Title: An exploration of mechanisms for the transformation of 8-oxoguanine to guanidinohydantoin and spiroiminodihydantoin by density functional theory.

Journal: Journal of the American Chemical Society 20080416

Title: The relationship between 8-oxo-7,8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas.

Journal: Mutation research 20080402

Title: Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells.

Journal: International journal of cancer 20080401

Title: Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation.

Journal: Carcinogenesis 20080401

Title: Effect of amino acids on X-ray-induced hydrogen peroxide and hydroxyl radical formation in water and 8-oxoguanine in DNA.

Journal: Biochemistry. Biokhimiia 20080401

Title: Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome.

Journal: Leukemia 20080301

Title: An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome.

Journal: PLoS genetics 20080301

Title: The genomics of colorectal cancer: state of the art.

Journal: Current genomics 20080301

Title: Separation of oxidatively damaged DNA nucleobases and nucleosides on packed and monolith C18 columns by HPLC-UV-EC.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215

Title: Oxidatively modified RNA in mild cognitive impairment.

Journal: Neurobiology of disease 20080201

Title: Overexpression of human NOX1 complex induces genome instability in mammalian cells.

Journal: Free radical biology & medicine 20080201

Title: Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population.

Journal: Cancer science 20080201

Title: DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression.

Journal: Science (New York, N.Y.) 20080111

Title: Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY.

Journal: Nature chemical biology 20080101

Title: Mechanism of oxidative DNA damage repair and relevance to human pathology.

Journal: Mutation research 20080101

Title: Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation.

Journal: Journal of neurochemistry 20080101

Title: Measurement and meaning of oxidatively modified DNA lesions in urine.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080101

Title: Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors.

Journal: Molecular cancer 20080101

Title: Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression.

Journal: Molecular vision 20080101

Title: Urinary excretion of an oxidative stress marker, 8-hydroxyguanine (8-OH-Gua), among nickel-cadmium battery workers.

Journal: Journal of occupational health 20080101

Title: Genotoxicity of combined exposure to polycyclic aromatic hydrocarbons and UVA--a mechanistic study.

Journal: Photochemistry and photobiology 20080101

Title: Analysis of the effects of exposure to acute hypoxia on oxidative lesions and tumour progression in a transgenic mouse breast cancer model.

Journal: BMC cancer 20080101

Title: A proposed framework for the interpretation of biomonitoring data.

Journal: Environmental health : a global access science source 20080101

Title: The Role of PPARs in Cancer.

Journal: PPAR research 20080101

Title: Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation.

Journal: BMC cancer 20080101

Title: Body iron metabolism and pathophysiology of iron overload.

Journal: International journal of hematology 20080101

Title: Design and chemical synthesis of a 2',4'-BNA probe for 7,8-dihydro-8-oxoguanine-containing double stranded DNA.

Journal: Nucleic acids symposium series (2004) 20080101

Title: Kinetics of dCTP incorporation opposite to 7,8-dihydro-8-oxoguanine with different 5' nearest neighbors by yeast polymerase eta.

Journal: Nucleic acids symposium series (2004) 20080101

Title: A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese.

Journal: BMC cancer 20080101

Title: Experimental observations of rapid Maize streak virus evolution reveal a strand-specific nucleotide substitution bias.

Journal: Virology journal 20080101

Title: Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet.

Journal: BMC molecular biology 20080101

Title: Prevention of oxidative DNA damage by bioactive berry components.

Journal: Nutrition and cancer 20080101

Title: Non-linear effects in the formation of DNA damage in medaka fish fibroblast cells caused by combined action of cadmium and ionizing radiation.

Journal: Dose-response : a publication of International Hormesis Society 20080101

Title: Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress.

Journal: Oxidative medicine and cellular longevity 20080101

Title: Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.

Journal: Biochemical and biophysical research communications 20071228

Title: The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.

Journal: Mutation research 20071201

Title: Human DNA polymerase lambda is a proficient extender of primer ends paired to 7,8-dihydro-8-oxoguanine.

Journal: DNA repair 20071201

Title: A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria.

Journal: DNA repair 20071201

Title: An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli.

Journal: DNA repair 20071201

Title: Relationship between the capacity to repair 8-oxoguanine, biomarkers of genotoxicity and individual susceptibility in styrene-exposed workers.

Journal: Mutation research 20071201

Title: Total antioxidant status and 8-hydroxy-2'-deoxyguanosine levels in gingival and peripheral blood of periodontitis patients.

Journal: Archivum immunologiae et therapiae experimentalis 20071201

Title: Chemical-biological fingerprinting: probing the properties of DNA lesions formed by peroxynitrite.

Journal: Chemical research in toxicology 20071101

Title: Urinary analysis of 8-oxoguanine, 8-oxoguanosine, fapy-guanine and 8-oxo-2'-deoxyguanosine by high-performance liquid chromatography-electrospray tandem mass spectrometry as a measure of oxidative stress.

Journal: Journal of chromatography. A 20071005

Title: Translocation of human ribosomal protein S3 to sites of DNA damage is dependant on ERK-mediated phosphorylation following genotoxic stress.

Journal: DNA repair 20071001

Title: Oxidation of guanine in double-stranded DNA by [Ru(bpy)2dppz]Cl2 in cationic reverse micelles.

Journal: Inorganic chemistry 20071001

Title: Human 8-oxoguanine DNA glycosylase suppresses the oxidative stress induced apoptosis through a p53-mediated signaling pathway in human fibroblasts.

Journal: Molecular cancer research : MCR 20071001

Title: Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage.

Journal: Toxicology letters 20070910

Title: Metabolic effects of static magnetic fields on Streptococcus pyogenes.

Journal: Bioelectromagnetics 20070901

Title: Transcription through 8-oxoguanine in DNA repair-proficient and Csb(-)/Ogg1(-) DNA repair-deficient mouse embryonic fibroblasts is dependent upon promoter strength and sequence context.

Journal: Mutagenesis 20070901

Title: Recombinant Schizosaccharomyces pombe Nth1 protein exhibits DNA glycosylase activities for 8-oxo-7,8-dihydroguanine and thymine residues oxidized in the methyl group.

Journal: Journal of radiation research 20070901

Title: Urinary excretion rates of 8-oxoGua and 8-oxodG and antioxidant vitamins level as a measure of oxidative status in healthy, full-term newborns.

Journal: Free radical research 20070901

Title: Nanoparticles-a thoracic toxicology perspective.

Journal: Yonsei medical journal 20070831

Title: The noncatalytic C-terminus of AtPOLK Y-family DNA polymerase affects synthesis fidelity, mismatch extension and translesion replication.

Journal: The FEBS journal 20070701

Title: The role of CSA in the response to oxidative DNA damage in human cells.

Journal: Oncogene 20070628

Title: Base-excision repair of oxidative DNA damage.

Journal: Nature 20070621

Title: Complementation of the oxidatively damaged DNA repair defect in Cockayne syndrome A and B cells by Escherichia coli formamidopyrimidine DNA glycosylase.

Journal: Free radical biology & medicine 20070615

Title: Accumulation of oxidatively induced DNA damage in human breast cancer cell lines following treatment with hydrogen peroxide.

Journal: Cell cycle (Georgetown, Tex.) 20070615

Title: Computational clues for a new mechanism in the glycosylase activity of the human DNA repair protein hOGG1. A generalized paradigm for purine-repairing systems?

Journal: The journal of physical chemistry. B 20070614

Title: RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS.

Journal: DNA repair 20070601

Title: Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice.

Journal: Cancer science 20070601

Title: Nickel(II)-catalysed oxidative guanine and DNA damage beyond 8-oxoguanine.

Journal: Free radical biology & medicine 20070601

Title: The peroxisome proliferator WY-14,643 promotes hepatocarcinogenesis caused by endogenously generated oxidative DNA base modifications in repair-deficient Csbm/m/Ogg1-/- mice.

Journal: Cancer research 20070601

Title: Studies on free radicals, antioxidants, and co-factors.

Journal: Clinical interventions in aging 20070601

Title: 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins.

Journal: Nature 20070531

Title: Lesion specificity in the base excision repair enzyme hNeil1: modeling and dynamics studies.

Journal: Biochemistry 20070508

Title: The mechanics of base excision repair, and its relationship to aging and disease.

Journal: DNA repair 20070401

Title: Oxidative damage to purines in DNA: role of mammalian Ogg1.

Journal: DNA repair 20070401

Title: Effects of basal level of antioxidants on oxidative DNA damage in humans.

Journal: European journal of nutrition 20070401

Title: Oxidative damage in nucleic acids and Parkinson's disease.

Journal: Journal of neuroscience research 20070401

Title: Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.

Journal: Cancer science 20070401

Title: Use of damaged DNA and dNTP substrates by the error-prone DNA polymerase X from African swine fever virus.

Journal: Biochemistry 20070327

Title: Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.

Journal: The Journal of biological chemistry 20070323

Title: Is the repair of oxidative DNA base modifications inducible by a preceding DNA damage induction?

Journal: DNA repair 20070301

Title: Exploration of mechanisms for the transformation of 8-hydroxy guanine radical to FAPyG by density functional theory.

Journal: Chemical research in toxicology 20070301

Title: The role of mitochondrial DNA mutations in mammalian aging.

Journal: PLoS genetics 20070201

Title: Assessment of DNA damage at the dimer level: measurement of the formamide lesion.

Journal: Radiation research 20070201

Title: Pre-steady-state kinetic study of substrate specificity of Escherichia coli formamidopyrimidine--DNA glycosylase.

Journal: Biochemistry 20070116

Title: Knockdown of ribosomal protein S3 protects human cells from genotoxic stress.

Journal: DNA repair 20070104

Title: Different DNA repair strategies to combat the threat from 8-oxoguanine.

Journal: Mutation research 20070103

Title: A theoretical study of some new analogues of the anti-cancer drug camptothecin.

Journal: Journal of molecular modeling 20070101

Title: Higher leukocyte 8-oxo-7,8-dihydro-2'-deoxyguanosine and lower plasma ascorbate in aging humans?

Journal: Antioxidants & redox signaling 20070101

Title: Oxidative damage to DNA and antioxidant status in aging and age-related diseases.

Journal: Acta biochimica Polonica 20070101

Title: Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides.

Journal: BMC structural biology 20070101

Title: Pro-oxidant effect of alpha-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test--a randomised controlled trial.

Journal: Cardiovascular diabetology 20070101

Title: [Oxygen effect in heat-mediated damage to DNA].

Journal: Biofizika 20070101

Title: The AnnoLite and AnnoLyze programs for comparative annotation of protein structures.

Journal: BMC bioinformatics 20070101

Title: A novel R229Q OGG1 polymorphism results in a thermolabile enzyme that sensitizes KG-1 leukemia cells to DNA damaging agents.

Journal: Cancer detection and prevention 20070101

Title: Study of molecular mechanisms of pro-apoptotic activity of NCX 4040, a novel nitric oxide-releasing aspirin, in colon cancer cell lines.

Journal: Journal of translational medicine 20070101

Title: Spore germination in Saccharomyces cerevisiae: global gene expression patterns and cell cycle landmarks.

Journal: Genome biology 20070101

Title: Nucleotide incorporation against 7,8-dihydro-8-oxoguanine is influenced by neighboring base sequences in TLS DNA polymerase reaction.

Journal: Nucleic acids symposium series (2004) 20070101

Title: GSTM1 and APE1 genotypes affect arsenic-induced oxidative stress: a repeated measures study.

Journal: Environmental health : a global access science source 20070101

Title: Base excision repair and the role of MUTYH.

Journal: Hereditary cancer in clinical practice 20070101

Title: Reduced repair of the oxidative 8-oxoguanine DNA damage and risk of head and neck cancer.

Journal: Cancer research 20061215

Title: Nonrandom AP site distribution in highly proliferative cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201

Title: Photoirradiation of polycyclic aromatic hydrocarbons with UVA light - a pathway leading to the generation of reactive oxygen species, lipid peroxidation, and dna damage.

Journal: International journal of environmental research and public health 20061201

Title: RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.

Journal: The EMBO journal 20061129

Title: Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9-Rad1-Hus1.

Journal: The Biochemical journal 20061115

Title: Inhibitory effect of 8-oxo-7,8-dihydro-2'-deoxyguanosine on the growth of KG-1 myelosarcoma in Balb/c nude mice.

Journal: Leukemia research 20061101

Title: Severe oxidatively damaged DNA after cisplatin treatment of cancer patients.

Journal: International journal of cancer 20061101

Title: 8-hydroxydeoxyguanosine suppresses NO production and COX-2 activity via Rac1/STATs signaling in LPS-induced brain microglia.

Journal: Free radical biology & medicine 20061101

Title: Genotoxicants target distinct molecular networks in neonatal neurons.

Journal: Environmental health perspectives 20061101

Title: High resolution characterization of formamidopyrimidine-DNA glycosylase interaction with its substrate by chemical cross-linking and mass spectrometry using substrate analogs.

Journal: The Journal of biological chemistry 20061027

Title: Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc finger.

Journal: Biochemistry 20061003

Title: Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis.

Journal: The American journal of pathology 20061001

Title: Nuclear magnetic resonance studies of the 4R and 4S diastereomers of spiroiminodihydantoin 2'-deoxyribonucleosides: absolute configuration and conformational features.

Journal: Chemical research in toxicology 20061001

Title: RNA damage and surveillance under oxidative stress.

Journal: IUBMB life 20061001

Title: New functions of XPC in the protection of human skin cells from oxidative damage.

Journal: The EMBO journal 20060920

Title: Oltipraz chemoprevention trial in Qidong, People's Republic of China: unaltered oxidative biomarkers.

Journal: Free radical biology & medicine 20060915

Title: A human cell-based assay to evaluate the effects of alterations in the MLH1 mismatch repair gene.

Journal: Cancer research 20060915

Title: Computational analysis of the mode of binding of 8-oxoguanine to formamidopyrimidine-DNA glycosylase.

Journal: Biochemistry 20060912

Title: DNA damage is an early event in doxorubicin-induced cardiac myocyte death.

Journal: American journal of physiology. Heart and circulatory physiology 20060901

Title: Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk.

Journal: Carcinogenesis 20060901

Title: Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.

Journal: ChemMedChem 20060901

Title: Effect of polyphenolic extract, Pycnogenol, on the level of 8-oxoguanine in children suffering from attention deficit/hyperactivity disorder.

Journal: Free radical research 20060901

Title: Anti-inflammatory effects of 8-hydroxydeoxyguanosine in LPS-induced microglia activation: suppression of STAT3-mediated intercellular adhesion molecule-1 expression.

Journal: Experimental & molecular medicine 20060831

Title: Oxidative damage to DNA: counterion-assisted addition of water to ionized DNA.

Journal: Journal of the American Chemical Society 20060823

Title: A distinct TthMutY bifunctional glycosylase that hydrolyzes not only adenine but also thymine opposite 8-oxoguanine in the hyperthermophilic bacterium, Thermus thermophilus.

Journal: DNA repair 20060813

Title: Functional flexibility of Bacillus stearothermophilus formamidopyrimidine DNA-glycosylase.

Journal: DNA repair 20060813

Title: Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk.

Journal: Cancer science 20060801

Title: Voltammetric determination of gamma radiation-induced DNA damage.

Journal: Analytical biochemistry 20060801

Title: Immunofluorescent detection of 8-oxoguanine DNA lesions in liver cells from aging OXYS rats, a strain prone to overproduction of free radicals.

Journal: Mutation research 20060725

Title: The high binding affinity of human ribosomal protein S3 to 7,8-dihydro-8-oxoguanine is abrogated by a single amino acid change.

Journal: DNA repair 20060713

Title: Assignment of absolute configurations of the enantiomeric spiroiminodihydantoin nucleobases by experimental and computational optical rotatory dispersion methods.

Journal: Chemical research in toxicology 20060701

Title: Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers.

Journal: British journal of cancer 20060619

Title: Modulation of the turnover of formamidopyrimidine DNA glycosylase.

Journal: Biochemistry 20060613

Title: Helicobacter hepaticus Dps protein plays an important role in protecting DNA from oxidative damage.

Journal: Free radical research 20060601

Title: Biomarkers signal contaminant effects on the organs of English sole (Parophrys vetulus) from Puget Sound.

Journal: Environmental health perspectives 20060601

Title: Chronic arsenic exposure and oxidative stress: OGG1 expression and arsenic exposure, nail selenium, and skin hyperkeratosis in Inner Mongolia.

Journal: Environmental health perspectives 20060601

Title: Oxidation of guanine in liver and lung DNA of prematurely aging OXYS rats.

Journal: Biochemistry. Biokhimiia 20060601

Title: 8-Oxo-7,8-dihydro-2'-deoxyguanosine is not salvaged for DNA synthesis in human leukemic U937 cells.

Journal: Free radical research 20060501

Title: hOGG1 recognizes oxidative damage using the comet assay with greater specificity than FPG or ENDOIII.

Journal: Mutagenesis 20060501

Title: Possible involvement of XPA in repair of oxidative DNA damage deduced from analysis of damage, repair and genotype in a human population study.

Journal: Mutagenesis 20060501

Title: A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome.

Journal: Genome research 20060501

Title: Elevated levels of urinary 8-hydroxy-2 -deoxyguanosine, lymphocytic micronuclei, and serum glutathione S-transferase in workers exposed to coke oven emissions.

Journal: Environmental health perspectives 20060501

Title: Mathematical modeling: epidemiology meets systems biology.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060501

Title: Estimating the effect of human base excision repair protein variants on the repair of oxidative DNA base damage.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060501

Title: Repair and mutagenesis at oxidized DNA lesions in the developing brain of wild-type and Ogg1-/- mice.

Journal: Oncogene 20060420

Title: Feasibility of conducting human studies to address bromate risks.

Journal: Toxicology 20060417

Title: DNA damage by bromate: mechanism and consequences.

Journal: Toxicology 20060417

Title: The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA.

Journal: Toxicology 20060417

Title: Exogenous 8-oxo-dG is not utilized for nucleotide synthesis but enhances the accumulation of 8-oxo-Gua in DNA through error-prone DNA synthesis.

Journal: Mutation research 20060411

Title: Role of the guanine N1 imino proton in the migration and reaction of radical cations in DNA oligomers.

Journal: Journal of the American Chemical Society 20060405

Title: Accelerated repair and reduced mutagenicity of oxidative DNA damage in human bladder cells expressing the E. coli FPG protein.

Journal: International journal of cancer 20060401

Title: MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Journal: Cell death and differentiation 20060401

Title: Singlet oxygen-induced DNA damage.

Journal: Radiation research 20060401

Title: Evidence for attenuated cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine removal in cancer patients.

Journal: Biological chemistry 20060401

Title: Cloning and characterization of an ascidian homolog of the human 8-oxoguanine DNA glycosylase (Ogg1) that is involved in the repair of 8-oxo-7,8-dihydroguanine in DNA in Ciona intestinalis.

Journal: International journal of radiation biology 20060401

Title: Dietary supplementation with different vitamin C doses: no effect on oxidative DNA damage in healthy people.

Journal: European journal of nutrition 20060301

Title: Helicobacter pylori infection is associated with oxidatively damaged DNA in human leukocytes and decreased level of urinary 8-oxo-7,8-dihydroguanine.

Journal: Carcinogenesis 20060301

Title: A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD.

Journal: Molecular microbiology 20060301

Title: Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo.

Journal: Molecular and cellular biology 20060301

Title: Structure of a DNA glycosylase searching for lesions.

Journal: Science (New York, N.Y.) 20060224

Title: MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060208

Title: Increased oxidative damage in nuclear and mitochondrial DNA in mild cognitive impairment.

Journal: Journal of neurochemistry 20060201

Title: Physical and functional interactions between Escherichia coli MutY and endonuclease VIII.

Journal: The Biochemical journal 20060101

Title: The reaction of water with guanosine radical cation in DNA.

Journal: Photochemistry and photobiology 20060101

Title: Guanine oxidation by electron transfer: one- versus two-electron oxidation mechanism.

Journal: Chembiochem : a European journal of chemical biology 20060101

Title: Thermostable DNA polymerases can perform translesion synthesis using 8-oxoguanine and tetrahydrofuran-containing DNA templates.

Journal: Biochimica et biophysica acta 20060101

Title: Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

Journal: PLoS biology 20060101

Title: Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors.

Journal: BMC cancer 20060101

Title: Gene-specific and mitochondrial repair of oxidative DNA damage.

Journal: Methods in molecular biology (Clifton, N.J.) 20060101

Title: Melatonin in Alzheimer's disease and other neurodegenerative disorders.

Journal: Behavioral and brain functions : BBF 20060101

Title: Urinary 8-hydroxyguanine may be a better marker of oxidative stress than 8-hydroxydeoxyguanosine in relation to the life spans of various species.

Journal: Antioxidants & redox signaling 20060101

Title: Urinary measurement of 8-OxodG, 8-OxoGua, and 5HMUra: a noninvasive assessment of oxidative damage to DNA.

Journal: Antioxidants & redox signaling 20060101

Title: Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights.

Journal: Photochemistry and photobiology 20060101

Title: The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.

Journal: Nucleic acids research 20060101

Title: Consequences of low birthweight on urinary excretion of DNA markers of oxidative stress in young men.

Journal: Scandinavian journal of clinical and laboratory investigation 20060101

Title: Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas.

Journal: BMC cancer 20060101

Title: Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.

Journal: BMC cancer 20060101

Title: DNA oxidation in Alzheimer's disease.

Journal: Antioxidants & redox signaling 20060101

Title: The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease.

Journal: Journal of neuroinflammation 20060101

Title: Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937.

Journal: BMC cancer 20060101

Title: Significance of 8-oxoG in the spectrum of DNA damages caused by ionising radiation of different quality.

Journal: Radiation protection dosimetry 20060101

Title: [From gene to disease; MutYH-associated polyposis coli (MAP)].

Journal: Nederlands tijdschrift voor geneeskunde 20051231

Title: Modulation of oxidative mutagenesis and carcinogenesis by polymorphic forms of human DNA repair enzymes.

Journal: Mutation research 20051211

Title: Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes.

Journal: The Journal of biological chemistry 20051209

Title: Oxidised guanidinohydantoin (Ghox) and spiroiminodihydantoin (Sp) are major products of iron- and copper-mediated 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine oxidation.

Journal: Molecular bioSystems 20051201

Title: Functional identification of an 8-oxoguanine specific endonuclease from Thermotoga maritima.

Journal: Journal of biochemistry and molecular biology 20051130

Title: Determination of 8-oxoguanine and 8-hydroxy-2'-deoxyguanosine in the rat cerebral cortex using microdialysis sampling and capillary electrophoresis with electrochemical detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051115

Title: OGG1 Cys326 variant, allelic imbalance of chromosome band 3p25.3 and TP53 mutations in ovarian cancer.

Journal: International journal of oncology 20051101

Title: Differential effects of 5-aminolaevulinic acid photodynamic therapy and psoralen + ultraviolet A therapy on p53 phosphorylation in normal human skin in vivo.

Journal: The British journal of dermatology 20051101

Title: DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.

Journal: Biochemistry 20051101

Title: Oxidative stress defense mechanisms to counter iron-promoted DNA damage in Helicobacter pylori.

Journal: Free radical research 20051101

Title: [Defense mechanisms against oxidative damage in mitochondrial genome].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20051101

Title: Structural and dynamic effects of single 7-hydro-8-oxoguanine bases located in a frameshift target DNA sequence.

Journal: Biophysical chemistry 20051022

Title: Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults.

Journal: Journal of neuroscience research 20051015

Title: Dynamic behavior of DNA base pairs containing 8-oxoguanine.

Journal: Journal of the American Chemical Society 20051012

Title: Structural and thermodynamic features of spiroiminodihydantoin damaged DNA duplexes.

Journal: Biochemistry 20051011

Title: The Helicobacter pylori MutS protein confers protection from oxidative DNA damage.

Journal: Molecular microbiology 20051001

Title: No major role for 7,8-dihydro-8-oxoguanine in ultraviolet light-induced mutagenesis.

Journal: Radiation research 20051001

Title: Increased levels of 8-hydroxy-2 -deoxyguanosine attributable to carcinogenic metal exposure among schoolchildren.

Journal: Environmental health perspectives 20051001

Title: Repair of tandem base lesions in DNA by human cell extracts generates persisting single-strand breaks.

Journal: Journal of molecular biology 20050902

Title: Effects of pH on nicotine-induced DNA damage and oxidative stress.

Journal: Journal of toxicology and environmental health. Part A 20050901

Title: Oxidation of guanine and 8-oxo-7,8-dihydroguanine by carbonate radical anions: insight from oxygen-18 labeling experiments.

Journal: Angewandte Chemie (International ed. in English) 20050812

Title: Effects of age and dietary restriction on oxidative DNA damage, antioxidant protection and DNA repair in rats.

Journal: European journal of nutrition 20050801

Title: Melatonin protects against MPTP/MPP+ -induced mitochondrial DNA oxidative damage in vivo and in vitro.

Journal: Journal of pineal research 20050801

Title: Methamphetamine-enhanced embryonic oxidative DNA damage and neurodevelopmental deficits.

Journal: Free radical biology & medicine 20050801

Title: MutYH (MYH) and colorectal cancer.

Journal: Biochemical Society transactions 20050801

Title: Mutagenesis of 8-oxoguanine adjacent to an abasic site in simian kidney cells: tandem mutations and enhancement of G-->T transversions.

Journal: Chemical research in toxicology 20050801

Title: Mechanisms of formation of 8-oxoguanine due to reactions of one and two OH* radicals and the H2O2 molecule with guanine: A quantum computational study.

Journal: The journal of physical chemistry. B 20050728

Title: 8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis.

Journal: Cancer research 20050715

Title: XRCC1 interactions with multiple DNA glycosylases: a model for its recruitment to base excision repair.

Journal: DNA repair 20050712

Title: Transcription promotes guanine to thymine mutations in the non-transcribed strand of an Escherichia coli gene.

Journal: DNA repair 20050712

Title: DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine.

Journal: Mutation research 20050701

Title: Oxidized guanine lesions and hOgg1 activity in lung cancer.

Journal: Oncogene 20050630

Title: Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.

Journal: Blood 20050615

Title: Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice.

Journal: The international journal of biochemistry & cell biology 20050601

Title: Molecular dynamics simulation of clustered DNA damage sites containing 8-oxoguanine and abasic site.

Journal: Journal of computational chemistry 20050601

Title: Allelic loss of the DNA repair gene OGG1 against oxidative damage in esophageal squamous cell carcinoma.

Journal: Oncology reports 20050601

Title: Error-prone and inefficient replication across 8-hydroxyguanine (8-oxoguanine) in human and mouse ras gene fragments by DNA polymerase kappa.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20050601

Title: DNA damages in ovarian surface epithelial cells of ovulatory hens.

Journal: Experimental biology and medicine (Maywood, N.J.) 20050601

Title: The Shizosaccharomyces pombe homolog (SpMYH) of the Escherichia coli MutY is required for removal of guanine from 8-oxoguanine/guanine mispairs to prevent G:C to C:G transversions.

Journal: Journal of radiation research 20050601

Title: Direct oxidative DNA damage, apoptosis and radio sensitivity by spermine oxidase activities in mouse neuroblastoma cells.

Journal: Biochimica et biophysica acta 20050525

Title: Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.

Journal: Biochemistry 20050503

Title: Endometriotic cells exhibit metaplastic change and oxidative DNA damage as well as decreased function, compared to normal endometrium.

Journal: Journal of molecular histology 20050501

Title: Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products.

Journal: Chemico-biological interactions 20050415

Title: hOGG1 Ser326Cys polymorphism and G:C-to-T:A mutations: no evidence for a role in tobacco-related non small cell lung cancer.

Journal: International journal of cancer 20050410

Title: Increased production of reactive oxygen species contributes to motor neuron death in a compression mouse model of spinal cord injury.

Journal: Spinal cord 20050401

Title: Somatic DNA oxidative damage and coronary disease.

Journal: Journal of molecular medicine (Berlin, Germany) 20050401

Title: The interrogator.

Journal: Nature structural & molecular biology 20050401

Title: [Biological consequences and base excision repair mechanisms of oxidative base damage in DNA].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20050401

Title: Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis.

Journal: Free radical research 20050401

Title: Structural biology: DNA search and rescue.

Journal: Nature 20050331

Title: Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA.

Journal: Nature 20050331

Title: Contribution of mitochondrial DNA repair to cell resistance from oxidative stress.

Journal: The Journal of biological chemistry 20050311

Title: Lung cancer in smoking patients inversely alters the activity of hOGG1 and hNTH1.

Journal: Cancer letters 20050310

Title: Product inhibition and magnesium modulate the dual reaction mode of hOgg1.

Journal: DNA repair 20050302

Title: Polymorphic variation in hOGG1 and risk of cancer: a review of the functional and epidemiologic literature.

Journal: Molecular carcinogenesis 20050301

Title: Determination of the stability constants and oxidation susceptibility of nickel(II) complexes with 2'-deoxyguanosine 5'-triphosphate and L-histidine.

Journal: Journal of inorganic biochemistry 20050301

Title: Combination reactions of superoxide with 8-Oxo-7,8-dihydroguanine radicals in DNA: kinetics and end products.

Journal: The Journal of biological chemistry 20050225

Title: Combination of nitrogen dioxide radicals with 8-oxo-7,8-dihydroguanine and guanine radicals in DNA: oxidation and nitration end-products.

Journal: Journal of the American Chemical Society 20050223

Title: Metallothionein reduces central nervous system inflammation, neurodegeneration, and cell death following kainic acid-induced epileptic seizures.

Journal: Journal of neuroscience research 20050215

Title: Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050201

Title: Kinetics of nucleotide incorporation opposite polycyclic aromatic hydrocarbon-DNA adducts by processive bacteriophage T7 DNA polymerase.

Journal: Chemical research in toxicology 20050201

Title: Lack of EGF receptor contributes to drug sensitivity of human germline cells.

Journal: British journal of cancer 20050131

Title: Interaction of checkpoint proteins Hus1/Rad1/Rad9 with DNA base excision repair enzyme MutY homolog in fission yeast, Schizosaccharomyces pombe.

Journal: The Journal of biological chemistry 20050107

Title: Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050101

Title: A DNA glycosylase from Pyrobaculum aerophilum with an 8-oxoguanine binding mode and a noncanonical helix-hairpin-helix structure.

Journal: Structure (London, England : 1993) 20050101

Title: Generation of 8-hydroxydeoxyguanosine from DNA using rat liver homogenates.

Journal: Cancer science 20050101

Title: Urea lesion formation in DNA as a consequence of 7,8-dihydro-8-oxoguanine oxidation and hydrolysis provides a potent source of point mutations.

Journal: Chemical research in toxicology 20050101

Title: [The formation of 8-oxoguanine and its oxidative products in DNA in vitro at 37 degrees C].

Journal: Biofizika 20050101

Title: Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast.

Journal: BMC genetics 20050101

Title: Biochemical markers and risk factors of Alzheimer's disease.

Journal: Current Alzheimer research 20050101

Title: DNA repair gene polymorphisms affect cytotoxicity in the National Cancer Institute Human Tumour Cell Line Screening Panel.

Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20050101

Title: Phosphorylation states of cell cycle and DNA repair proteins can be altered by the nsSNPs.

Journal: BMC cancer 20050101

Title: 8-oxoguanine DNA glycosylase, but not Kin17 protein, is translocated and differentially regulated by estrogens in rat brain cells.

Journal: Neuroscience 20050101

Title: Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich.

Journal: BMC genomics 20050101

Title: [Chronobiological evaluation of effects biomarkers and sampling].

Journal: Giornale italiano di medicina del lavoro ed ergonomia 20050101

Title: Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure.

Journal: Particle and fibre toxicology 20050101

Title: Polymorphisms of the human OGG1 gene in laryngeal cancer: implications in radiotherapy response and survival.

Journal: Revue de laryngologie - otologie - rhinologie 20050101

Title: Kinetics and thermodynamics of G-quadruplexes.

Journal: Nucleic acids symposium series (2004) 20050101

Title: Repair of the oxidative DNA damage 8-oxoguanine as a biomarker for lung cancer risk.

Journal: Cancer biomarkers : section A of Disease markers 20050101

Title: Frequency of the Common MYH Mutations (G382D and Y165C) in MMR Mutation Positive and Negative HNPCC Patients.

Journal: Hereditary cancer in clinical practice 20050101

Title: Substrate discrimination by formamidopyrimidine-DNA glycosylase: distinguishing interactions within the active site.

Journal: Biochemistry 20041228

Title: Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA.

Journal: Biochemistry 20041221

Title: Peroxyl radical mediated oxidative DNA base damage: implications for lipid peroxidation induced mutagenesis.

Journal: Biochemistry 20041214

Title: An Escherichia coli MutY mutant without the six-helix barrel domain is a dimer in solution and assembles cooperatively into multisubunit complexes with DNA.

Journal: The Journal of biological chemistry 20041210

Title: Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer.

Journal: Carcinogenesis 20041201

Title: Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells.

Journal: Mutation research 20041122

Title: Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1.

Journal: Biochemistry 20041109

Title: Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase.

Journal: The Journal of biological chemistry 20041105

Title: Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats.

Journal: Annals of the New York Academy of Sciences 20041101

Title: Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine.

Journal: Free radical research 20041101

Title: Structural basis for the recognition of the FapydG lesion (2,6-diamino-4-hydroxy-5-formamidopyrimidine) by formamidopyrimidine-DNA glycosylase.

Journal: The Journal of biological chemistry 20041015

Title: Suppression of chemically induced and spontaneously occurring oxidative mutagenesis by three alleles of human OGG1 gene encoding 8-hydroxyguanine DNA glycosylase.

Journal: Mutation research 20041004

Title: A novel splice-site variant of the base excision repair gene MYH is associated with production of an aberrant mRNA transcript encoding a truncated MYH protein not localized in the nucleus.

Journal: Carcinogenesis 20041001

Title: An oligonucleotide microarray for the monitoring of repair enzyme activity toward different DNA base damage.

Journal: Analytical biochemistry 20041001

Title: Spirodihydantoin is a minor product of 5-hydroxyisourate in urate oxidation.

Journal: Organic letters 20040916

Title: Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases.

Journal: Biochemistry 20040914

Title: Differential ability of polymorphic OGG1 proteins to suppress mutagenesis induced by 8-hydroxyguanine in human cell in vivo.

Journal: Carcinogenesis 20040901

Title: Electrochemical study of quercetin-DNA interactions: part I. Analysis in incubated solutions.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040901

Title: Electrochemical study of quercetin-DNA interactions: part II. In situ sensing with DNA biosensors.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040901

Title: Analysis of 8-hydroxyguanine (8-OH-Gua) released from DNA by the formamidopyrimidine DNA glycosylase (Fpg) protein: a reliable method to estimate cellular oxidative stress.

Journal: Journal of radiation research 20040901

Title: Biology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorder.

Journal: Dialogues in clinical neuroscience 20040901

Title: Metallothionein-III prevents gamma-ray-induced 8-oxoguanine accumulation in normal and hOGG1-depleted cells.

Journal: The Journal of biological chemistry 20040813

Title: Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.

Journal: Carcinogenesis 20040801

Title: Oxidative DNA damage associated with combination of guanine and superoxide radicals and repair mechanisms via radical trapping.

Journal: The Journal of biological chemistry 20040730

Title: Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases.

Journal: Cancer research 20040701

Title: Single extraction protocol for the analysis of 8-hydroxy-2'-deoxyguanosine (oxo8dG) and the associated activity of 8-oxoguanine DNA glycosylase.

Journal: Journal of neuroscience methods 20040615

Title: Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo.

Journal: Carcinogenesis 20040601

Title: A high-throughput and sensitive methodology for the quantification of urinary 8-hydroxy-2'-deoxyguanosine: measurement with gas chromatography-mass spectrometry after single solid-phase extraction.

Journal: The Biochemical journal 20040601

Title: Electrochemical determination of 8-oxoguanine in the presence of uric acid.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20040601

Title: Role of reactive oxygen species in skin carcinogenesis.

Journal: Antioxidants & redox signaling 20040601

Title: Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: carcinogenic implication and chemoprevention.

Journal: Experimental biology and medicine (Maywood, N.J.) 20040601

Title: Development of an HPLC method with electrochemical detection of femtomoles of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine in the presence of uric acid.

Journal: Talanta 20040528

Title: Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II.

Journal: DNA repair 20040504

Title: In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040501

Title: Role of inherited defects of MYH in the development of sporadic colorectal cancer.

Journal: Genes, chromosomes & cancer 20040501

Title: Oxygen tension regulates reactive oxygen generation and mutation of Helicobacter pylori.

Journal: Free radical biology & medicine 20040501

Title: Effects of melanin and manganese on DNA damage and repair in PC12-derived neurons.

Journal: Free radical biology & medicine 20040501

Title: Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.

Journal: The Journal of biological chemistry 20040430

Title: Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.

Journal: The Journal of biological chemistry 20040409

Title: Mutagenicities of 8-hydroxyguanine and 2-hydroxyadenine produced by reactive oxygen species.

Journal: Biological & pharmaceutical bulletin 20040401

Title: Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of Mammalian cells.

Journal: Free radical biology & medicine 20040315

Title: 8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site.

Journal: DNA repair 20040304

Title: Overexpression and rapid purification of Escherichia coli formamidopyrimidine-DNA glycosylase.

Journal: Protein expression and purification 20040301

Title: Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells?

Journal: Archives of biochemistry and biophysics 20040301

Title: Molecular biology: ensuring error-free DNA repair.

Journal: Nature 20040212

Title: Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase.

Journal: Nature 20040212

Title: Characterization of human ribosomal protein S3 binding to 7,8-dihydro-8-oxoguanine and abasic sites by surface plasmon resonance.

Journal: DNA repair 20040203

Title: Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells.

Journal: Antioxidants & redox signaling 20040201

Title: Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators.

Journal: Cancer research 20040201

Title: Detection of a smaller, 32-kDa 8-oxoguanine DNA glycosylase 1 in 3'-methyl-4-dimethylamino-azobenzene-treated mouse liver.

Journal: Cancer science 20040201

Title: Cadmium-induced apoptosis in C6 glioma cells: influence of oxidative stress.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20040201

Title: Different toxic, fibrogenic and mutagenic effects of four commercial quartz flours in the rat lung.

Journal: International journal of hygiene and environmental health 20040201

Title: DNA glycosylase recognition and catalysis.

Journal: Current opinion in structural biology 20040201

Title: Orchestration of base excision repair by controlling the rates of enzymatic activities.

Journal: DNA repair 20040105

Title: 8-Oxoguanine induces intramolecular DNA damage but free 8-oxoguanine protects intermolecular DNA from oxidative stress.

Journal: FEBS letters 20040102

Title: Excision by the human methylpurine DNA N-glycosylase of cyanuric acid, a stable and mutagenic oxidation product of 8-oxo-7,8-dihydroguanine.

Journal: International journal of radiation biology 20040101

Title: Radiation-induced DNA damage: formation, measurement, and biochemical features.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101

Title: Effects of 'second-hand' smoke on structure and function of fibroblasts, cells that are critical for tissue repair and remodeling.

Journal: BMC cell biology 20040101

Title: Potassium bromate but not X-rays cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblasts.

Journal: Cytogenetic and genome research 20040101

Title: Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase.

Journal: Respiratory research 20040101

Title: [New non-hydrolyzable substrate analogs for 8-oxoguanine-DNA glycosylases].

Journal: Molekuliarnaia biologiia 20040101

Title: Expression of the Drosophila melanogaster S3 ribosomal/repair protein in T24 human bladder cells.

Journal: Anticancer research 20040101

Title: UVA-induced degradation of 8-hydroxyguanine in oligonucleotide and the effect on its activities in yeast oligonucleotide transformation assay.

Journal: Nucleic acids symposium series (2004) 20040101

Title: DNA lesion recognition by the bacterial repair enzyme MutM.

Journal: The Journal of biological chemistry 20031219

Title: Detection of attomole quantities [correction of quantitites] of DNA targets on gold microelectrodes by electrocatalytic nucleobase oxidation.

Journal: Analytical chemistry 20031201

Title: DNA lesions derived from the site selective oxidation of Guanine by carbonate radical anions.

Journal: Chemical research in toxicology 20031201

Title: Strand-specific processing of 8-oxoguanine by the human mismatch repair pathway: inefficient removal of 8-oxoguanine paired with adenine or cytosine.

Journal: DNA repair 20031121

Title: Effect of the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin on proofreading by Escherichia coli DNA polymerase I (Klenow fragment) in different sequence contexts.

Journal: Biochemistry 20031111

Title: Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1.

Journal: The Journal of biological chemistry 20031107

Title: Oxidative DNA damage induced by benz[a]anthracene metabolites via redox cycles of quinone and unique non-quinone.

Journal: Chemical research in toxicology 20031101

Title: Oxidative DNA damage and glioma cell death induced by tetrahydropapaveroline.

Journal: Mutation research 20031101

Title: Transcription-coupled repair of 8-oxoguanine in human cells and its deficiency in some DNA repair diseases.

Journal: Biochimie 20031101

Title: Oxidative damage to DNA: formation, measurement and biochemical features.

Journal: Mutation research 20031029

Title: 8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways.

Journal: Mutation research 20031029

Title: Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?

Journal: Mutation research 20031029

Title: The two main DNA lesions 8-Oxo-7,8-dihydroguanine and 2,6-diamino-5-formamido-4-hydroxypyrimidine exhibit strongly different pairing properties.

Journal: Angewandte Chemie (International ed. in English) 20031020

Title: Oxidative DNA damage in peripheral leukocytes and its association with expression and polymorphisms of hOGG1: a study of adolescents in a high risk region for hepatocellular carcinoma in China.

Journal: World journal of gastroenterology 20031015

Title: Intramolecular electrocatalysis of 8-oxo-guanine oxidation: secondary structure control of electron transfer in osmium-labeled oligonucleotides.

Journal: Inorganic chemistry 20031006

Title: Better late than never for repair of miscoding lesions within a transcribed template.

Journal: Molecular cell 20031001

Title: Transcriptional mutagenesis induced by uracil and 8-oxoguanine in Escherichia coli.

Journal: Molecular cell 20031001

Title: Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis.

Journal: Cellular and molecular life sciences : CMLS 20031001

Title: Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20030916

Title: Evaluation of genotoxic risk and oxidative DNA damage in mammalian cells exposed to mycotoxins, patulin and citrinin.

Journal: Toxicology and applied pharmacology 20030915

Title: The molecular epidemiology of oxidative damage to DNA and cancer.

Journal: Journal of the National Cancer Institute 20030903

Title: DNA repair activity for oxidative damage and risk of lung cancer.

Journal: Journal of the National Cancer Institute 20030903

Title: Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kappaB promoter element.

Journal: Biochemistry 20030819

Title: Products of oxidative DNA damage and repair as possible biomarkers of susceptibility to lung cancer.

Journal: Cancer research 20030815

Title: The hydantoin lesions formed from oxidation of 7,8-dihydro-8-oxoguanine are potent sources of replication errors in vivo.

Journal: Biochemistry 20030812

Title: Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation.

Journal: Biochemistry 20030805

Title: Urinary 8-hydroxydeoxyguanosine and its analogs as DNA marker of oxidative stress: development of an ELISA and measurement in both bladder and prostate cancers.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030801

Title: Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA.

Journal: Cancer research 20030715

Title: Chemical restriction: strand cleavage by ammonia treatment at 8-oxoguanine yields biologically active DNA.

Journal: Chembiochem : a European journal of chemical biology 20030707

Title: High concentrations of excised oxidative DNA lesions in human cerebrospinal fluid.

Journal: Clinical chemistry 20030701

Title: Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups.

Journal: European journal of biochemistry 20030701

Title: Electrostatic energy analysis of 8-oxoguanine DNA lesion-molecular dynamics study.

Journal: Computational biology and chemistry 20030701

Title: The mutation frequency of 8-oxo-7,8-dihydroguanine (8-oxodG) situated in a multiply damaged site: comparison of a single and two closely opposed 8-oxodG in Escherichia coli.

Journal: DNA repair 20030611

Title: Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells.

Journal: DNA repair 20030611

Title: Oscillating formation of 8-oxoguanine during DNA oxidation.

Journal: Journal of the American Chemical Society 20030604

Title: Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles.

Journal: Acta neuropathologica 20030601

Title: Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030601

Title: Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: untreated and surface treated.

Journal: Toxicology and applied pharmacology 20030601

Title: Aldehydic DNA lesions induced by catechol estrogens in calf thymus DNA.

Journal: Carcinogenesis 20030601

Title: Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo.

Journal: Carcinogenesis 20030601

Title: 8-Oxoguanine enhances bending of DNA that favors binding to glycosylases.

Journal: Journal of the American Chemical Society 20030521

Title: Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta.

Journal: The Journal of biological chemistry 20030516

Title: Endonuclease IV enhances base excision repair of endonuclease III from Methanobacterium thermoautotrophicum.

Journal: DNA repair 20030513

Title: 8-oxoguanine lesioned B-DNA molecule complexed with repair enzyme hOGG1: a molecular dynamics study.

Journal: Journal of computational chemistry 20030501

Title: A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides.

Journal: EMBO reports 20030501

Title: Use of crosslinking for revealing the DNA phosphate groups forming specific contacts with the E. coli Fpg protein.

Journal: Biochimie 20030501

Title: hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women.

Journal: Breast cancer research and treatment 20030501

Title: Expression of hOGG1 protein during differentiation of HL-60 cells.

Journal: Experimental & molecular medicine 20030430

Title: Base excision repair synthesis of DNA containing 8-oxoguanine in Escherichia coli.

Journal: Experimental & molecular medicine 20030430

Title: Evidence for preferential mismatch repair of lagging strand DNA replication errors in yeast.

Journal: Current biology : CB 20030429

Title: Measurement of DNA oxidation in human cells by chromatographic and enzymic methods.

Journal: Free radical biology & medicine 20030415

Title: Characterization of an Escherichia coli mutant MutY with a cysteine to alanine mutation at the iron-sulfur cluster domain.

Journal: Biochemistry 20030408

Title: Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401

Title: Long-patch DNA repair synthesis during base excision repair in mammalian cells.

Journal: EMBO reports 20030401

Title: Arabidopsis thaliana Ogg1 protein excises 8-hydroxyguanine and 2,6-diamino-4-hydroxy-5-formamidopyrimidine from oxidatively damaged DNA containing multiple lesions.

Journal: Biochemistry 20030318

Title: Cadmium exposure down-regulates 8-oxoguanine DNA glycosylase expression in rat lung and alveolar epithelial cells.

Journal: Toxicology 20030303

Title: Product-assisted catalysis in base-excision DNA repair.

Journal: Nature structural biology 20030301

Title: Electron and hole transfer from DNA base radicals to oxidized products of guanine in DNA.

Journal: Radiation research 20030301

Title: Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption.

Journal: Cancer research 20030301

Title: Nutritional modulation of DNA repair in a human intervention study.

Journal: Carcinogenesis 20030301

Title: Oxidative DNA base modifications and polycyclic aromatic hydrocarbon DNA adducts in squamous cell carcinoma of larynx.

Journal: Free radical research 20030301

Title: Metaplastic potential of p53 down-regulation in ovarian surface epithelial cells affected by ovulation.

Journal: Cancer letters 20030227

Title: Marathon running alters the DNA base excision repair in human skeletal muscle.

Journal: Life sciences 20030221

Title: Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney.

Journal: DNA repair 20030203

Title: Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide.

Journal: Chemical research in toxicology 20030201

Title: 8-hydroxydeoxyguanosine causes death of human leukemia cells deficient in 8-oxoguanine glycosylase 1 activity by inducing apoptosis.

Journal: Molecular cancer research : MCR 20030201

Title: Escherichia coli MutY and Fpg utilize a processive mechanism for target location.

Journal: Biochemistry 20030128

Title: An improved liquid chromatography/tandem mass spectrometry method for the determination of 8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA samples using immunoaffinity column purification.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: Hold tight (but not too tight) to get it right: accurate bypass of an 8-oxoguanine lesion by DNA polymerase beta.

Journal: Structure (London, England : 1993) 20030101

Title: Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected.

Journal: Carcinogenesis 20030101

Title: Age-dependent increase of 8-oxoguanine-, hypoxanthine-, and uracil- DNA glycosylase activities in liver extracts from OXYS rats with inherited overgeneration of free radicals and Wistar rats.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20030101

Title: Measurement of oxidative damage at individual gene levels by quantitative PCR using 8-hydroxyguanine glycosylase (OGG1).

Journal: Mutation research 20030101

Title: Ovarian responses to undernutrition in pregnant ewes, USA.

Journal: Reproductive biology and endocrinology : RB&E 20030101

Title: Preparation of DNA-protein complexes suitable for spectroscopic analysis.

Journal: Methods in molecular medicine 20030101

Title: Analysis of 8-hydroxydeoxyguanosine 5'-monophosphate (8-OH-dGMP) as a reliable marker of cellular oxidative DNA damage after gamma-irradiation.

Journal: Environmental and molecular mutagenesis 20030101

Title: Drosophila S3 ribosomal protein accelerates repair of 8-oxoguanine performed by human and mouse cell extracts.

Journal: Environmental and molecular mutagenesis 20030101

Title: Effect of S. cerevisiae APN1 protein on mammalian DNA base excision repair.

Journal: Anticancer research 20030101

Title: [Study of formation and elimination of 8-oxoguanine in DNA of the liver and brain of mice after gamma-irradiation].

Journal: Radiatsionnaia biologiia, radioecologiia 20030101

Title: Efficiency, specificity and DNA polymerase-dependence of translesion replication across the oxidative DNA lesion 8-oxoguanine in human cells.

Journal: Mutation research 20021229

Title: In vitro nucleotide misinsertion opposite the oxidized guanosine lesions spiroiminodihydantoin and guanidinohydantoin and DNA synthesis past the lesions using Escherichia coli DNA polymerase I (Klenow fragment).

Journal: Biochemistry 20021224

Title: Oxidative nucleotide damage: consequences and prevention.

Journal: Oncogene 20021216

Title: 8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells.

Journal: Cancer research 20021215

Title: Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B.

Journal: Oncogene 20021212

Title: Sorting the consequences of ionizing radiation: processing of 8-oxoguanine/abasic site lesions.

Journal: DNA repair 20021205

Title: High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress.

Journal: Carcinogenesis 20021201

Title: Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus.

Journal: Carcinogenesis 20021201

Title: Ultraviolet-B-induced inactivation of human OGG1, the repair enzyme for removal of 8-oxoguanine in DNA.

Journal: Photochemistry and photobiology 20021201

Title: A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage.

Journal: Oncogene 20021128

Title: The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells.

Journal: Biochimica et biophysica acta 20021120

Title: Functional crosstalk between hOgg1 and the helicase domain of Cockayne syndrome group B protein.

Journal: DNA repair 20021103

Title: Binding capacity of human YB-1 protein for RNA containing 8-oxoguanine.

Journal: Biochemistry 20021022

Title: Temperature-dependence of UV laser one-electron oxidative guanine modifications as a probe of local stacking fluctuations and conformational transitions.

Journal: Journal of molecular biology 20021011

Title: Acute arsenite-induced 8-hydroxyguanine is associated with inhibition of repair activity in cultured human cells.

Journal: Biochemical and biophysical research communications 20021004

Title: The level of 8-hydroxyguanine, a possible repair product of oxidative DNA damage, is higher in urine of cancer patients than in control subjects.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021001

Title: Structure and potential mutagenicity of new hydantoin products from guanosine and 8-oxo-7,8-dihydroguanine oxidation by transition metals.

Journal: Environmental health perspectives 20021001

Title: Guanine and 7,8-dihydro-8-oxo-guanine-specific oxidation in DNA by chromium(V).

Journal: Environmental health perspectives 20021001

Title: Oxidative stress in humans: validation of biomarkers of DNA damage.

Journal: Carcinogenesis 20020901

Title: Loss of oxidized and chlorinated bases in DNA treated with reactive oxygen species: implications for assessment of oxidative damage in vivo.

Journal: Biochemical and biophysical research communications 20020830

Title: The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA.

Journal: The Journal of biological chemistry 20020823

Title: Base excision repair of adenine/8-oxoguanine mispairs by an aphidicolin-sensitive DNA polymerase in human cell extracts.

Journal: Oncogene 20020808

Title: First principles calculations of the tautomers and pK(a) values of 8-oxoguanine: implications for mutagenicity and repair.

Journal: Chemical research in toxicology 20020801

Title: NTA and Fe(III)NTA: differential patterns of renal toxicity in subchronic studies.

Journal: Human & experimental toxicology 20020801

Title: Establishment and characterisation of six human biliary tract cancer cell lines.

Journal: British journal of cancer 20020715

Title: Yeast origins establish a strand bias for replicational mutagenesis.

Journal: Molecular cell 20020701

Title: Thermodynamic, kinetic, and structural basis for recognition and repair of 8-oxoguanine in DNA by Fpg protein from Escherichia coli.

Journal: Biochemistry 20020618

Title: Repair of clustered DNA lesions. Sequence-specific inhibition of long-patch base excision repair be 8-oxoguanine.

Journal: The Journal of biological chemistry 20020614

Title: Gene-specific oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa.

Journal: International journal of cancer 20020601

Title: hOGG1 Ser(326)Cys polymorphism and modification by environmental factors of stomach cancer risk in Chinese.

Journal: International journal of cancer 20020601

Title: Mutagenic target for hydroxyl radicals generated in Escherichia coli mutant deficient in Mn- and Fe- superoxide dismutases and Fur, a repressor for iron-uptake systems.

Journal: DNA repair 20020530

Title: Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product.

Journal: Oncogene 20020516

Title: Translesion synthesis by human DNA polymerase eta across thymine glycol lesions.

Journal: Biochemistry 20020514

Title: Vitamin C prevents DNA mutation induced by oxidative stress.

Journal: The Journal of biological chemistry 20020510

Title: Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells.

Journal: Free radical biology & medicine 20020501

Title: Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA.

Journal: Free radical biology & medicine 20020501

Title: A single nucleotide polymorphism at the splice donor site of the human MYH base excision repair genes results in reduced translation efficiency of its transcripts.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20020501

Title: A limited association of OGG1 Ser326Cys polymorphism for adenocarcinoma of the lung.

Journal: Journal of epidemiology 20020501

Title: Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias.

Journal: DNA repair 20020429

Title: Effects of a guanine-derived formamidopyrimidine lesion on DNA replication: translesion DNA synthesis, nucleotide insertion, and extension kinetics.

Journal: The Journal of biological chemistry 20020426

Title: The effect of DNA damage on the formation of protein/DNA complexes.

Journal: Mutation research 20020425

Title: Associations between hOGG1 sequence variants and prostate cancer susceptibility.

Journal: Cancer research 20020415

Title: Regulation of one-electron oxidation rate of guanine by base pairing with cytosine derivatives.

Journal: Journal of the American Chemical Society 20020410

Title: Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe.

Journal: The Journal of biological chemistry 20020405

Title: Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis.

Journal: Acta neuropathologica 20020401

Title: Molecular dynamics simulation of 7, 8-dihydro-8-oxoguanine DNA.

Journal: Journal of biomolecular structure & dynamics 20020401

Title: Association of the hOGG1 Ser326Cys polymorphism with lung cancer risk.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20020401

Title: Reciprocal 'flipping' underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase.

Journal: Journal of molecular biology 20020322

Title: Activation of human MutS homologs by 8-oxo-guanine DNA damage.

Journal: The Journal of biological chemistry 20020308

Title: Relations between clusters of oxidatively damaged nucleotides and active or open nucleosomes in the rat Nth 1 gene.

Journal: Oncogene 20020307

Title: Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines.

Journal: Cancer research 20020301

Title: DNA tandem lesions containing 8-oxo-7,8-dihydroguanine and formamido residues arise from intramolecular addition of thymine peroxyl radical to guanine.

Journal: Chemical research in toxicology 20020301

Title: Hypoxia induces mitochondrial DNA damage and stimulates expression of a DNA repair enzyme, the Escherichia coli MutY DNA glycosylase homolog (MYH), in vivo, in the rat brain.

Journal: Journal of neurochemistry 20020301

Title: Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2'-deoxyguanosine in DNA.

Journal: Free radical research 20020301

Title: Site-specific probing of oxidative reactivity and telomerase function using 7,8-dihydro-8-oxoguanine in telomeric DNA.

Journal: Journal of the American Chemical Society 20020227

Title: Replication-associated repair of adenine:8-oxoguanine mispairs by MYH.

Journal: Current biology : CB 20020219

Title: Stopped-flow kinetic studies of the interaction between Escherichia coli Fpg protein and DNA substrates.

Journal: Biochemistry 20020205

Title: Radiation sensitivity depends on OGG1 activity status in human leukemia cell lines.

Journal: Free radical biology & medicine 20020201

Title: Gender differences in steady-state levels of oxidative damage to DNA in healthy individuals.

Journal: Free radical research 20020201

Title: Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo.

Journal: Biochemistry 20020122

Title: Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues.

Journal: Environmental and molecular mutagenesis 20020101

Title: [18O]-labeled singlet oxygen as a tool for mechanistic studies of 8-oxo-7,8-dihydroguanine oxidative damage: detection of spiroiminodihydantoin, imidazolone and oxazolone derivatives.

Journal: Biological chemistry 20020101

Title: Transcription-coupled repair of 8-oxoguanine in human cells.

Journal: Methods in enzymology 20020101

Title: Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA.

Journal: Cancer detection and prevention 20020101

Title: Asymmetric directional mutation pressures in bacteria.

Journal: Genome biology 20020101

Title: Mitochondrial repair of 8-oxoguanine and changes with aging.

Journal: Experimental gerontology 20020101

Title: Backbone dynamics of DNA containing 8-oxoguanine: importance for substrate recognition by base excision repair glycosylases.

Journal: Mutation research 20011219

Title: Effect of overexpression of BCL-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome.

Journal: Free radical biology & medicine 20011215

Title: The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA.

Journal: The Journal of biological chemistry 20011207

Title: DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts.

Journal: The EMBO journal 20011203

Title: Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats.

Journal: Diabetes 20011201

Title: An OGG1 orthologue encoding a functional 8-oxoguanine DNA glycosylase/lyase in Arabidopsis thaliana.

Journal: Plant molecular biology 20011201

Title: 8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine levels in human urine do not depend on diet.

Journal: Free radical research 20011201

Title: Increased base change mutations at G:C pairs in Escherichia coli deficient in endonuclease III and VIII.

Journal: Journal of radiation research 20011201

Title: UV laser photolysis of DNA: effect of duplex stability on charge-transfer efficiency.

Journal: Journal of the American Chemical Society 20011121

Title: Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines.

Journal: The EMBO journal 20011115

Title: Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosis.

Journal: Biology of reproduction 20011101

Title: A platinum(IV) complex oxidizes guanine to 8-oxo-guanine in DNA and RNA.

Journal: Inorganic chemistry 20011022

Title: Efficiency of excision of 8-oxo-guanine within DNA clustered damage by XRS5 nuclear extracts and purified human OGG1 protein.

Journal: Biochemistry 20011002

Title: Fission yeast (Schizosaccharomyces pombe) cells defective in the MutY-homologous glycosylase activity have a mutator phenotype and are sensitive to hydrogen peroxide.

Journal: Molecular genetics and genomics : MGG 20011001

Title: Direct photocleavage of HIV-DNA by quinacridine derivatives triggered by triplex formation.

Journal: Journal of the American Chemical Society 20010926

Title: Effect of single mutations on the specificity of Escherichia coli FPG protein for excision of purine lesions from DNA damaged by free radicals.

Journal: Free radical biology & medicine 20010915

Title: Human Ogg1, a protein involved in the repair of 8-oxoguanine, is inhibited by nitric oxide.

Journal: Cancer research 20010901

Title: Imaging techniques used for the detection of 8-oxoguanine adducts and DNA repair proteins in cells and tissues.

Journal: Experimental gerontology 20010901

Title: OGG1 protein suppresses G:C-->T:A mutation in a shuttle vector containing 8-hydroxyguanine in human cells.

Journal: Carcinogenesis 20010901

Title: Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice.

Journal: Carcinogenesis 20010901

Title: Direct oxidation of guanine and 7,8-dihydro-8-oxoguanine in DNA by a high-valent chromium complex: a possible mechanism for chromate genotoxicity.

Journal: Chemical research in toxicology 20010901

Title: Sequence specificity of the 8-hydroxyguanine repair activity in rat organs.

Journal: Journal of radiation research 20010901

Title: Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein.

Journal: Biochemistry 20010821

Title: Age-related radical-induced DNA damage is linked to prostate cancer.

Journal: Cancer research 20010815

Title: DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326.

Journal: Mutation research 20010809

Title: Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine.

Journal: Biochemical and biophysical research communications 20010803

Title: The OGG1 gene encodes a repair enzyme for oxidatively damaged DNA and is involved in human carcinogenesis.

Journal: Antioxidants & redox signaling 20010801

Title: [Repair mechanism of oxidative DNA damages].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010801

Title: Polyploidy associated with oxidative injury attenuates proliferative potential of cells.

Journal: Journal of cell science 20010801

Title: Conversion of the bifunctional 8-oxoguanine/beta-delta apurinic/apyrimidinic DNA repair activities of Drosophila ribosomal protein S3 into the human S3 monofunctional beta-elimination catalyst through a single amino acid change.

Journal: The Journal of biological chemistry 20010720

Title: Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice.

Journal: Cancer research 20010715

Title: Cellular effects of 5-formyluracil in DNA.

Journal: Mutation research 20010712

Title: DNA repair excision nuclease attacks undamaged DNA. A potential source of spontaneous mutations.

Journal: The Journal of biological chemistry 20010706

Title: Inter-individual differences in repair of DNA base oxidation, measured in vitro with the comet assay.

Journal: Mutagenesis 20010701

Title: Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production.

Journal: Journal of neurochemistry 20010701

Title: hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs.

Journal: Nucleic acids research 20010701

Title: Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2.

Journal: Journal of neurochemistry 20010701

Title: The pyrimidine ring-opened derivative of 1,N6-ethenoadenine is excised from DNA by the Escherichia coli Fpg and Nth proteins.

Journal: The Journal of biological chemistry 20010615

Title: Determination of 8-oxoguanine in individual cell nucleus of gamma-irradiated mammalian cells.

Journal: Radiation research 20010601

Title: An in vivo approach to identifying sequence context of 8-oxoguanine mutagenesis.

Journal: Biochemical and biophysical research communications 20010601

Title: [Biological significance of base damage and its repair in brain and neurons].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010601

Title: [Repair networks for base damage and single-strand breaks].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20010601

Title: Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury.

Journal: Neurobiology of disease 20010601

Title: Ser326Cys polymorphism in hOGG1 gene and risk of esophageal cancer in a Chinese population.

Journal: International journal of cancer 20010520

Title: Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.

Journal: Biochemistry 20010515

Title: Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence.

Journal: Free radical biology & medicine 20010515

Title: Somatic mutations and single nucleotide polymorphisms of base excision repair genes involved in the repair of 8-hydroxyguanine in damaged DNA.

Journal: Cancer letters 20010510

Title: Biomonitoring on carcinogenic metals and oxidative DNA damage in a cross-sectional study.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010501

Title: Oxidative DNA damage, antioxidants and DNA repair: applications of the comet assay.

Journal: Biochemical Society transactions 20010501

Title: Base excision and DNA binding activities of human alkyladenine DNA glycosylase are sensitive to the base paired with a lesion.

Journal: The Journal of biological chemistry 20010420

Title: Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering.

Journal: Circulation research 20010413

Title: Quartz exposure of the rat lung leads to a linear dose response in inflammation but not in oxidative DNA damage and mutagenicity.

Journal: American journal of respiratory cell and molecular biology 20010401

Title: Serum 8-hydroxy-guanine levels are increased in diabetic patients.

Journal: Diabetes care 20010401

Title: Possible cause of G-C-->C-G transversion mutation by guanine oxidation product, imidazolone.

Journal: Chemistry & biology 20010401

Title: GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.

Journal: Archives of biochemistry and biophysics 20010401

Title: A functional OGG1 homologue from Arabidopsis thaliana.

Journal: Molecular genetics and genomics : MGG 20010401

Title: Debenzylation of O(6)-benzyl-8-oxoguanine in human liver: implications for O(6)-benzylguanine metabolism.

Journal: Biochemical pharmacology 20010315

Title: The Drosophila S3 multifunctional DNA repair/ribosomal protein protects Fanconi anemia cells against oxidative DNA damaging agents.

Journal: Mutation research 20010307

Title: Rates of base excision repair are not solely dependent on levels of initiating enzymes.

Journal: Carcinogenesis 20010301

Title: New biochemical markers in Alzheimer disease.

Journal: Archives of neurology 20010301

Title: Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid.

Journal: Archives of neurology 20010301

Title: Fidelity of nucleotide insertion at 8-oxo-7,8-dihydroguanine by mammalian DNA polymerase delta. Steady-state and pre-steady-state kinetic analysis.

Journal: The Journal of biological chemistry 20010209

Title: Significant differences in the cellular and molecular reactions of rat and hamster lung after quartz exposure.

Journal: Toxicology letters 20010203

Title: Changes in DNA 8-hydroxyguanine levels, 8-hydroxyguanine repair activity, and hOGG1 and hMTH1 mRNA expression in human lung alveolar epithelial cells induced by crocidolite asbestos.

Journal: Carcinogenesis 20010201

Title: Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis.

Journal: Journal of neurochemistry 20010201

Title: Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult.

Journal: Journal of neurochemistry 20010201

Title: Genetic changes of hOGG1 and the activity of oh8Gua glycosylase in colon cancer.

Journal: European journal of cancer (Oxford, England : 1990) 20010201

Title: Miscoding and misincorporation of 8-oxo-guanine during leading and lagging strand synthesis in Escherichia coli.

Journal: Molecular & general genetics : MGG 20010201

Title: Effect of endogenous carotenoids on 'adaptive' mutation in Escherichia coli FC40.

Journal: Mutation research 20010125

Title: tert-Butoxyl radicals generate mainly 7,8-dihydro-8-oxoguanine in DNA.

Journal: Mutation research 20010105

Title: Repair and mutagenic potential of oxaluric acid, a major product of singlet oxygen-mediated oxidation of 8-oxo-7,8-dihydroguanine.

Journal: Chemical research in toxicology 20010101

Title: Evidence of a no-effect level in silica-induced rat lung mutagenicity but not in fibrogenicity.

Journal: Archives of toxicology 20010101

Title: Mammalian Ogg1/Mmh gene plays a major role in repair of the 8-hydroxyguanine lesion in DNA.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Base excision repair in nuclear and mitochondrial DNA.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: The mechanism of switching among multiple BER pathways.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Potential double-flipping mechanism by E. coli MutY.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Repair of 8-oxoguanine and Ogg1-incised apurinic sites in a CHO cell line.

Journal: Progress in nucleic acid research and molecular biology 20010101

Title: Consequences of haemolysis without haptoglobin.

Journal: Redox report : communications in free radical research 20010101

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