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56180-94-0,MFCD23136977
Catalog No.:AA00I9YC

56180-94-0 | Acarbose

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1mg
98%
in stock  
$6.00   $4.00
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50mg
98%
in stock  
$7.00   $5.00
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250mg
98%
in stock  
$19.00   $14.00
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1g
98%
in stock  
$37.00   $26.00
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5g
95 - 102% (HPLC)
in stock  
$107.00   $75.00
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25g
95 - 102% (HPLC)
in stock  
$313.00   $219.00
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100g
95 - 102% (HPLC)
in stock  
$787.00   $551.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I9YC
Chemical Name:
Acarbose
CAS Number:
56180-94-0
Molecular Formula:
C25H43NO18
Molecular Weight:
645.6048
MDL Number:
MFCD23136977
SMILES:
OC[C@H]([C@H]([C@@H]([C@H](C=O)O)O)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O[C@H]1O[C@H](C)[C@H]([C@@H]([C@H]1O)O)N[C@H]1C=C(CO)[C@H]([C@@H]([C@H]1O)O)O)O
NSC Number:
758915
Properties
Computed Properties
 
Complexity:
962  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
18  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
19  
Hydrogen Bond Donor Count:
14  
Rotatable Bond Count:
9  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-8.5  

Downstream Synthesis Route
56180-94-0    585-88-6   
4-{5-3,4-dihydroxy-6-methyl-5-(4,5,6-trihydroxy-3-hydroxymethyl-cyclohex-2-enylamino)-tetrahydro-pyran-2-yloxy-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy}-hexane-1,2,3,5,6-pentaol 
 
4-(6-{5-3,4-dihydroxy-6-methyl-5-(4,5,6-trihydroxy-3-hydroxymethyl-cyclohex-2-enylamino)-tetrahydro-pyran-2-yloxy-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl}-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxy)-hexane-1,2,3,5,6-pentaol 

[1]CarbohydrateResearch,1998,vol.313,p.235-246

[2]CarbohydrateResearch,1998,vol.313,p.235-246

Literature

Title: Berry components inhibit α-glucosidase in vitro: synergies between acarbose and polyphenols from black currant and rowanberry.

Journal: Food chemistry 20121201

Title: Acarbose treatment enhances mid-regional pro-atrial natriuretic peptide concentrations in non-diabetic individuals: further evidence for a common cardiometabolic pathway?

Journal: Diabetologia 20121201

Title: Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.

Journal: International journal of food sciences and nutrition 20121101

Title: Pharmacodynamic bioequivalence testing.

Journal: Journal of clinical pharmacy and therapeutics 20121001

Title: Pharmacodynamic comparison of two formulations of Acarbose 100-mg tablets.

Journal: Journal of clinical pharmacy and therapeutics 20121001

Title: In vitro studies to assess the antidiabetic, antiperoxidative, and radical scavenging potential of Stereospermum colais.

Journal: Pharmaceutical biology 20121001

Title: Effects on lipid profile of dipeptidyl peptidase 4 inhibitors, pioglitazone, acarbose, and sulfonylureas: meta-analysis of placebo-controlled trials.

Journal: Advances in therapy 20120901

Title: Intestinal alpha-glucosidase inhibitors: abdominal gas cysts.

Journal: Prescrire international 20120901

Title: An optimized industrial fermentation processes for acarbose production by Actinoplanes sp. A56.

Journal: Bioresource technology 20120801

Title: Usefulness of acarbose and dietary modifications to limit glycemic variability following Roux-en-Y gastric bypass as assessed by continuous glucose monitoring.

Journal: Diabetes technology & therapeutics 20120801

Title: [Improvement in blood glucose fluctuations of insulin-treated type 1 diabetic patients with additional use of acarbose and assessed by continuous blood glucose monitoring program].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20120801

Title: Alpha-glucosidase inhibitors 2012 - cardiovascular considerations and trial evaluation.

Journal: Diabetes & vascular disease research 20120701

Title: Acarbose is an effective treatment for severe hypertriglyceridemia secondary to l-asparaginase and dexamethasone.

Journal: Leukemia & lymphoma 20120601

Title: Acarbose bioequivalence: exploration of new pharmacodynamic parameters.

Journal: The AAPS journal 20120601

Title: Efficacy and safety profile evaluation of acarbose alone and in association with other antidiabetic drugs: a systematic review.

Journal: Clinical therapeutics 20120601

Title: Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine.

Journal: Journal of microbiology and biotechnology 20120601

Title: Potent α-glucosidase inhibitors from safflower (Carthamus tinctorius L.) seed.

Journal: Phytotherapy research : PTR 20120501

Title: Initiation of insulin among veterans with type 2 diabetes and sustained elevation of A1c.

Journal: Primary care diabetes 20120401

Title: Acarbose improves hypoglycaemia following gastric bypass surgery without increasing glucagon-like peptide 1 levels.

Journal: Obesity surgery 20120401

Title: Crystal structures of receptors involved in small molecule transport across membranes.

Journal: European journal of cell biology 20120401

Title: Successful use of acarbose to manage post-prandial glycaemia in two patients with type 1 diabetes on continuous subcutaneous insulin infusion.

Journal: Diabetes research and clinical practice 20120301

Title: A novel synergistic galactomannan-based unit dosage form for sustained release of acarbose.

Journal: AAPS PharmSciTech 20120301

Title: Management of overt hepatic encephalopathy.

Journal: Clinics in liver disease 20120201

Title: An effective and simplified scale-up strategy for acarbose fermentation based on the carbon source control.

Journal: World journal of microbiology & biotechnology 20120201

Title: Actinoplanes utahensis ZJB-08196 fed-batch fermentation at elevated osmolality for enhancing acarbose production.

Journal: Bioresource technology 20120101

Title: Maplexins, new α-glucosidase inhibitors from red maple (Acer rubrum) stems.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: Podocyte as a potential target of inflammation: role of pioglitazone hydrochloride in patients with type 2 diabetes.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20120101

Title: The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.

Journal: BMC genomics 20120101

Title: Early improvement in carotid plaque echogenicity by acarbose in patients with acute coronary syndromes.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Utility of an oxidation reaction for the spectrophotometric determination of acarbose in controlled release tablets at various simulated gastrointestinal media.

Journal: Acta poloniae pharmaceutica 20120101

Title: Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine.

Journal: PloS one 20120101

Title: Effects of acarbose versus glibenclamide on glycemic excursion and oxidative stress in type 2 diabetic patients inadequately controlled by metformin: a 24-week, randomized, open-label, parallel-group comparison.

Journal: Clinical therapeutics 20111201

Title: Structural insight into substrate specificity of human intestinal maltase-glucoamylase.

Journal: Protein & cell 20111001

Title: A high-throughput assay for quantification of starch hydrolase inhibition based on turbidity measurement.

Journal: Journal of agricultural and food chemistry 20110928

Title: Images in clinical medicine. Pneumatosis cystoides intestinalis.

Journal: The New England journal of medicine 20110825

Title: Alterations of antioxidant biomarkers and type I collagen deposition in the parotid gland of streptozotocin-induced diabetic rats.

Journal: Archives of oral biology 20110801

Title: The alpha (α)-glucosidase inhibitor, acarbose, attenuates the blood pressure and splanchnic blood flow responses to intraduodenal sucrose in older adults.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20110801

Title: Mapping the intestinal alpha-glucogenic enzyme specificities of starch digesting maltase-glucoamylase and sucrase-isomaltase.

Journal: Bioorganic & medicinal chemistry 20110701

Title: Safety and efficacy of high-dose acarbose treatment for dumping syndrome.

Journal: Journal of pediatric gastroenterology and nutrition 20110701

Title: Nateglinide and acarbose for postprandial glucose control after optimizing fasting glucose with insulin glargine in patients with type 2 diabetes.

Journal: Diabetes research and clinical practice 20110601

Title: Effects of acarbose treatment on markers of insulin sensitivity and systemic inflammation.

Journal: Diabetes technology & therapeutics 20110601

Title: Inhibitory activity of cinnamon bark species and their combination effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20110601

Title: International noninterventional study of acarbose treatment in patients with type 2 diabetes mellitus.

Journal: Diabetes research and clinical practice 20110401

Title: Evaluation of efficacy of acarbose on glucose fluctuation and postprandial glucose using continuous glucose monitoring in type 2 diabetes mellitus.

Journal: Diabetes technology & therapeutics 20110401

Title: [Analogues of amylin, alpha-glucosidase inhibitors and the digestive system in homeostasis regulation].

Journal: Vnitrni lekarstvi 20110401

Title: [Dyspeptic syndrome associated with antidiabetic therapy].

Journal: Vnitrni lekarstvi 20110401

Title: (Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor.

Journal: Journal of natural products 20110325

Title: In vitro inhibitory effects of cyandin-3-rutinoside on pancreatic α-amylase and its combined effect with acarbose.

Journal: Molecules (Basel, Switzerland) 20110302

Title: Comparing the efficacy of α-glucosidase inhibitors in suppressing postprandial hyperglycemia using continuous glucose monitoring: a pilot study-the MAJOR study.

Journal: Diabetes technology & therapeutics 20110301

Title: Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for β-D-galactopyranose.

Journal: Journal of molecular biology 20110211

Title: Oral hypoglycaemic agents during pregnancy: The evidence for effectiveness and safety.

Journal: Best practice & research. Clinical obstetrics & gynaecology 20110201

Title: A-glucosidase inhibitory activity of kaempferol-3-O-rutinoside.

Journal: Natural product communications 20110201

Title: Acarbose actions on insulin resistance and inflammatory parameters during an oral fat load.

Journal: European journal of pharmacology 20110125

Title: Potent α-amylase inhibitory activity of Indian Ayurvedic medicinal plants.

Journal: BMC complementary and alternative medicine 20110101

Title: Glycemic variability in insulin treated type 2 diabetes with well-controlled hemoglobin A1c and its response to further treatment with acarbose.

Journal: Chinese medical journal 20110101

Title: RETRACTED: Acarbose on insulin resistance after an oral fat load: a double-blind, placebo controlled study.

Journal: Journal of diabetes and its complications 20110101

Title: Effects of onion (Allium cepa L.) extract administration on intestinal α-glucosidases activities and spikes in postprandial blood glucose levels in SD rats model.

Journal: International journal of molecular sciences 20110101

Title: The beneficial effect of α-glucosidase inhibitor on glucose variability compared with sulfonylurea in Taiwanese type 2 diabetic patients inadequately controlled with metformin: preliminary data.

Journal: Journal of diabetes and its complications 20110101

Title: Oligosaccharide sensing with chromophore-modified curdlan in aqueous media.

Journal: Chemical communications (Cambridge, England) 20101228

Title: The α-glucosidase inhibitor miglitol decreases glucose fluctuations and inflammatory cytokine gene expression in peripheral leukocytes of Japanese patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20101201

Title: Carbohydrate and fat digestion is necessary for maximal suppression of total plasma ghrelin in healthy adults.

Journal: Appetite 20101201

Title: Post-translational derepression of invertase activity in source leaves via down-regulation of invertase inhibitor expression is part of the plant defense response.

Journal: Molecular plant 20101101

Title: Post-prandial carbohydrate modulation via gut--Indian perspective.

Journal: The Journal of the Association of Physicians of India 20101101

Title: A prospective, parallel group, open-labeled, comparative, multi-centric, active controlled study to evaluate the safety, tolerability and benefits of fixed dose combination of acarbose and metformin versus metformin alone in type 2 diabetes.

Journal: The Journal of the Association of Physicians of India 20101101

Title: The effects of acarbose treatment on intimal hyperplasia in a rat carotid endarterectomy model of diet-induced insulin resistance.

Journal: Vascular and endovascular surgery 20101001

Title: Effect of pioglitazone and acarbose on endothelial inflammation biomarkers during oral glucose tolerance test in diabetic patients treated with sulphonylureas and metformin.

Journal: Journal of clinical pharmacy and therapeutics 20101001

Title: alpha-Glucosidase inhibitory activities of 10-hydroxy-8(E)-octadecenoic acid: an intermediate of bioconversion of oleic acid to 7,10-dihydroxy-8(E)-octadecenoic acid.

Journal: New biotechnology 20100930

Title: Yeast α-glucosidase inhibition by isoflavones from plants of Leguminosae as an in vitro alternative to acarbose.

Journal: Journal of agricultural and food chemistry 20100922

Title: Modified alpha-amylase activity among insecticide-resistant and -susceptible strains of the maize weevil, Sitophilus zeamais.

Journal: Journal of insect physiology 20100901

Title: Acarbose reduces the risk of pre-lunch hypoglycemia in elderly people with diabetes eating rice porridge for breakfast.

Journal: Diabetes research and clinical practice 20100901

Title: Metformin versus acarbose therapy in patients with polycystic ovary syndrome (PCOS): a prospective randomised double-blind study.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100901

Title: Current and emerging strategies for treating hepatic encephalopathy.

Journal: Critical care nursing clinics of North America 20100901

Title: Clinical Inquiries: How can we keep impaired glucose tolerance and impaired fasting glucose from progressing to diabetes?

Journal: The Journal of family practice 20100901

Title: The glucoamylase inhibitor acarbose is a direct activator of phosphorylase kinase.

Journal: Biochemistry 20100810

Title: Bioinformatic and biochemical studies point to AAGR-1 as the ortholog of human acid alpha-glucosidase in Caenorhabditis elegans.

Journal: Molecular and cellular biochemistry 20100801

Title: Influence of glycemic control on the development of diabetic cardiovascular and kidney disease.

Journal: Cardiology clinics 20100801

Title: Frequent reoccurrence of hypoglycemia in a type 2 diabetic patient with insulin antibodies.

Journal: Molecular diagnosis & therapy 20100801

Title: Impact of acarbose on carotid intima-media thickness in patients with newly diagnosed impaired glucose tolerance or mild type 2 diabetes mellitus: A one-year, prospective, randomized, open-label, parallel-group study in Japanese adults with established coronary artery disease.

Journal: Clinical therapeutics 20100801

Title: Simultaneous determination of substrate and product in the process of preparation of valienamine by capillary zone electrophoresis.

Journal: Journal of separation science 20100701

Title: An alpha-glucosidase inhibitor, acarbose treatment decreases serum levels of glyceraldehyde-derived advanced glycation end products (AGEs) in patients with type 2 diabetes.

Journal: Clinical and experimental medicine 20100601

Title: Combination of acarbose and ezetimibe prevents non-alcoholic fatty liver disease: a break of intestinal insulin resistance?

Journal: Journal of hepatology 20100601

Title: Preventive treatment with acarbose in diabetic reactive hypoglycemia.

Journal: Journal of the American Medical Directors Association 20100601

Title: Glipizide controlled-release tablets, with or without acarbose, improve glycaemic variability in newly diagnosed Type 2 diabetes.

Journal: Clinical and experimental pharmacology & physiology 20100501

Title: Crystal structures of the solute receptor GacH of Streptomyces glaucescens in complex with acarbose and an acarbose homolog: comparison with the acarbose-loaded maltose-binding protein of Salmonella typhimurium.

Journal: Journal of molecular biology 20100402

Title: Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus.

Journal: Journal of thrombosis and haemostasis : JTH 20100401

Title: Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100401

Title: Antioxidant and enzyme inhibition activities and chemical profiles of Polygonum sachalinensis F.Schmidt ex Maxim (Polygonaceae).

Journal: Fitoterapia 20100301

Title: Glucose supply and insulin demand dynamics of antidiabetic agents.

Journal: Journal of diabetes science and technology 20100301

Title: Development and validation of HPLC-UV-MS method for the control of four anti-diabetic drugs in suspected counterfeit products.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100301

Title: SusG: a unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules.

Journal: Structure (London, England : 1993) 20100210

Title: Effects of acarbose on ruminal fermentation, blood metabolites and microbial profile involved in ruminal acidosis in lactating cows fed a high-carbohydrate ration.

Journal: The Journal of dairy research 20100201

Title: In vitro studies on the hypoglycemic potential of Ficus racemosa stem bark.

Journal: Journal of the science of food and agriculture 20100201

Title: New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata.

Journal: Biochemistry 20100126

Title: Postprandial endothelial dysfunction in subjects with new-onset type 2 diabetes: an acarbose and nateglinide comparative study.

Journal: Cardiovascular diabetology 20100101

Title: Comparison of adverse gastrointestinal effects of acarbose and miglitol in healthy men: a crossover study.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Effects of acarbose on the acceleration of postprandial hyperglycemia-induced pathological changes induced by intermittent hypoxia in lean mice.

Journal: Journal of pharmacological sciences 20100101

Title: Inhibitory activities of cyanidin and its glycosides and synergistic effect with acarbose against intestinal α-glucosidase and pancreatic α-amylase.

Journal: International journal of molecular sciences 20100101

Title: Inhibitory effect of CuSO₄ on α-glucosidase activity in ddY mice.

Journal: Metallomics : integrated biometal science 20100101

Title: Comparative evaluation of quercetin, isoquercetin and rutin as inhibitors of alpha-glucosidase.

Journal: Journal of agricultural and food chemistry 20091223

Title: Modulation of adipokines and vascular remodelling markers during OGTT with acarbose or pioglitazone treatment.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091201

Title: Does postprandial blood glucose matter and why?

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20091201

Title: Effect of acarbose on platelet-derived microparticles, soluble selectins, and adiponectin in diabetic patients.

Journal: Journal of thrombosis and thrombolysis 20091101

Title: Inhibitory effect of methanol extract of Rosa damascena Mill. flowers on alpha-glucosidase activity and postprandial hyperglycemia in normal and diabetic rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20091001

Title: Pathophysiology, diagnosis and management of postoperative dumping syndrome.

Journal: Nature reviews. Gastroenterology & hepatology 20091001

Title: What are the best options for controlling prandial glycemia?

Journal: Current diabetes reports 20091001

Title: Long-term combination therapy of ezetimibe and acarbose for non-alcoholic fatty liver disease.

Journal: Journal of hepatology 20090901

Title: Effect of acarbose on milk yield and composition in early-lactation dairy cattle fed a ration to induce subacute ruminal acidosis.

Journal: Journal of dairy science 20090901

Title: Effects of acarbose on proinsulin and insulin secretion and their potential significance for the intermediary metabolism and cardiovascular system.

Journal: Current diabetes reviews 20090801

Title: Antidiabetic activities of Tecoma stans (L.) Juss. ex Kunth.

Journal: Journal of ethnopharmacology 20090715

Title: Are the effects of alpha-glucosidase inhibitors on cardiovascular events related to elevated levels of hydrogen gas in the gastrointestinal tract?

Journal: FEBS letters 20090707

Title: Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.

Journal: Journal of cardiovascular pharmacology 20090701

Title: Enzyme analysis for Pompe disease in leukocytes; superior results with natural substrate compared with artificial substrates.

Journal: Journal of inherited metabolic disease 20090601

Title: Effect of acarbose on acute acidosis.

Journal: Journal of dairy science 20090601

Title: Effects of changeover from voglibose to acarbose on postprandial triglycerides in type 2 diabetes mellitus patients.

Journal: Advances in therapy 20090601

Title: The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice.

Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20090501

Title: Acarbose attenuates postprandial hyperlipidemia: investigation in an intestinal absorptive cell model.

Journal: Metabolism: clinical and experimental 20090501

Title: [Diagnostic standard for fasting and postprandial hyperglycemia].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090410

Title: Alpha-glucosidase inhibition assay in an enzyme-immobilized amino-microplate.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090401

Title: [A comparison of efficacy and tolerance of nateglinide and acarbose monotherapy in type 2 diabetes mellitus].

Journal: Zhonghua nei ke za zhi 20090401

Title: The gac-gene cluster for the production of acarbose from Streptomyces glaucescens GLA.O: identification, isolation and characterization.

Journal: Journal of biotechnology 20090310

Title: Metabolic effect of repaglinide or acarbose when added to a double oral antidiabetic treatment with sulphonylureas and metformin: a double-blind, cross-over, clinical trial.

Journal: Current medical research and opinion 20090301

Title: alpha-Glucosidase inhibitory activity of cyanidin-3-galactoside and synergistic effect with acarbose.

Journal: Journal of enzyme inhibition and medicinal chemistry 20090201

Title: Antidiabetic effect of an active fraction extracted from dragon's blood (Dracaena Cochinchinensis).

Journal: Journal of enzyme inhibition and medicinal chemistry 20090201

Title: Effects of the alpha glucosidase inhibitor acarbose on endothelial function after a mixed meal in newly diagnosed type 2 diabetes.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090201

Title: Effect of acarbose on postmeal mononuclear blood cell response in patients with early type 2 diabetes: the AI(I)DA study.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090201

Title: Clinical utility of acarbose, an alpha-glucosidase inhibitor in cardiometabolic disorders.

Journal: Current drug metabolism 20090201

Title: [Alpha-glucosidase inhibitors from Luculia pinciana].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090201

Title: Benefits and risks of oral diabetes agents compared with insulin in women with gestational diabetes: a systematic review.

Journal: Obstetrics and gynecology 20090101

Title: Effects of alpha-amylase and its inhibitors on acid production from cooked starch by oral streptococci.

Journal: Caries research 20090101

Title: Metabolic syndrome and its single traits as risk factors for diabetes in people with impaired glucose tolerance: the STOP-NIDDM trial.

Journal: Diabetes & vascular disease research 20090101

Title: The investigation of the efficacy of insulin glargine on glycemic control when combined with either repaglinide or acarbose in obese Type 2 diabetic patients.

Journal: Journal of endocrinological investigation 20090101

Title: Oral antidiabetic agents: anti-atherosclerotic properties beyond glucose lowering?

Journal: Current pharmaceutical design 20090101

Title: Influence of acarbose on blood glucose and breath hydrogen after carbohydrate load with sucrose or starch.

Journal: Arzneimittel-Forschung 20090101

Title: Probing the role of aromatic residues at the secondary saccharide-binding sites of human salivary alpha-amylase in substrate hydrolysis and bacterial binding.

Journal: Journal of molecular biology 20081231

Title: Post-prandial hypoglycemia after bariatric surgery: pharmacological treatment with verapamil and acarbose.

Journal: Obesity surgery 20081201

Title: Acute generalized exanthematous pustulosis possibly induced by acarbose.

Journal: International journal of dermatology 20081201

Title: The effects of medications used for the management of diabetes and obesity on postprandial lipid metabolism.

Journal: Current diabetes reviews 20081101

Title: Efficacy and safety of acarbose in the treatment of elderly patients with postprandial hypotension.

Journal: Chinese medical journal 20081020

Title: Structural insight into the bifunctional mechanism of the glycogen-debranching enzyme TreX from the archaeon Sulfolobus solfataricus.

Journal: The Journal of biological chemistry 20081017

Title: Clinical, endocrine, and metabolic effects of acarbose, a alpha-glucosidase inhibitor, in overweight and nonoverweight patients with polycystic ovarian syndrome.

Journal: Fertility and sterility 20081001

Title: Three trehalose synthetic pathways in the acarbose-producing Actinoplanes sp. SN223/29 and evidence for the TreY role in biosynthesis of component C.

Journal: Applied microbiology and biotechnology 20081001

Title: Genetic organization of the putative salbostatin biosynthetic gene cluster including the 2-epi-5-epi-valiolone synthase gene in Streptomyces albus ATCC 21838.

Journal: Applied microbiology and biotechnology 20080901

Title: Miglitol suppresses the postprandial increase in interleukin 6 and enhances active glucagon-like peptide 1 secretion in viscerally obese subjects.

Journal: Metabolism: clinical and experimental 20080901

Title: Acarbose feeding increases pancreatic islet blood flow in obese glucose-intolerant Otsuka Long-Evans Tokushima fatty rats.

Journal: Pancreas 20080801

Title: Modulation of hydrolysis and transglycosylation activity of Thermus maltogenic amylase by combinatorial saturation mutagenesis.

Journal: Journal of microbiology and biotechnology 20080801

Title: Reduction in post-prandial hyperglycemic excursion through alpha-glucosidase inhibition by beta-acetamido carbonyl compounds.

Journal: Bioorganic & medicinal chemistry letters 20080715

Title: Enzymatic synthesis of a selective inhibitor for alpha-glucosidases: alpha-acarviosinyl-(1-->9)-3-alpha-D-glucopyranosylpropen.

Journal: Journal of agricultural and food chemistry 20080709

Title: Acarbose treatment increases serum total adiponectin levels in patients with type 2 diabetes.

Journal: Endocrine journal 20080701

Title: Pharmacologic treatment options for prediabetes.

Journal: Nature clinical practice. Endocrinology & metabolism 20080701

Title: Discovery and biological evaluation of novel alpha-glucosidase inhibitors with in vivo antidiabetic effect.

Journal: Bioorganic & medicinal chemistry letters 20080701

Title: [The comparison about inhibition of five Chinese herbal medicines to two different resources alpha-glycosidase].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080701

Title: Effect of acarbose on vascular disease in patients with abnormal glucose tolerance.

Journal: Cardiovascular drugs and therapy 20080601

Title: Acarbose for polycystic ovary syndrome.

Journal: The Annals of pharmacotherapy 20080601

Title: Effect of acarbose on the increased plasma concentration of uric acid induced by sucrose ingestion.

Journal: Nucleosides, nucleotides & nucleic acids 20080601

Title: Effect of acarbose, an alpha-glucosidase inhibitor, on serum lipoprotein lipase mass levels and common carotid artery intima-media thickness in type 2 diabetes mellitus treated by sulfonylurea.

Journal: Journal of atherosclerosis and thrombosis 20080601

Title: Hepatotoxicity caused by both tacrolimus and cyclosporine after living donor liver transplantation.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20080601

Title: Alpha-glucosidase inhibitory activity of Syzygium cumini (Linn.) Skeels seed kernel in vitro and in Goto-Kakizaki (GK) rats.

Journal: Carbohydrate research 20080519

Title: Crystal structure of the polyextremophilic alpha-amylase AmyB from Halothermothrix orenii: details of a productive enzyme-substrate complex and an N domain with a role in binding raw starch.

Journal: Journal of molecular biology 20080509

Title: Evolution toward small molecule inhibitor resistance affects native enzyme function and stability, generating acarbose-insensitive cyclodextrin glucanotransferase variants.

Journal: The Journal of biological chemistry 20080418

Title: Four acarviosin-containing oligosaccharides identified from Streptomyces coelicoflavus ZG0656 are potent inhibitors of alpha-amylase.

Journal: Carbohydrate research 20080407

Title: The alpha-glucosidase inhibitor acarbose reduces the net electronegative charge of low-density lipoprotein in patients with newly diagnosed type 2 diabetes.

Journal: Clinica chimica acta; international journal of clinical chemistry 20080401

Title: Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20080401

Title: Acarbose alleviates rise in plasma uric acid concentration induced by sucrose ingestion.

Journal: International journal of clinical pharmacology and therapeutics 20080401

Title: [The effectiveness in type 2 diabetes prevention: a forced landing to reality].

Journal: Medicina clinica 20080308

Title: Effects of chronic acarbose treatment on adipocyte insulin responsiveness, serum levels of leptin and adiponectin and hypothalamic NPY expression in obese diabetic Wistar rats.

Journal: Clinical and experimental pharmacology & physiology 20080301

Title: [Adjunctive therapies to glycaemic control of type 1 diabetes mellitus].

Journal: Arquivos brasileiros de endocrinologia e metabologia 20080301

Title: Acarbose: oral anti-diabetes drug with additional cardiovascular benefits.

Journal: Expert review of cardiovascular therapy 20080201

Title: Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity.

Journal: Journal of molecular biology 20080118

Title: [The possibility of prevention of type 2 diabetes].

Journal: Endokrynologia Polska 20080101

Title: A study of the effects of acarbose on glucose metabolism in patients predisposed to developing diabetes: the Dutch acarbose intervention study in persons with impaired glucose tolerance (DAISI).

Journal: Diabetes/metabolism research and reviews 20080101

Title: Identification and treatment of prediabetes to prevent progression to type 2 diabetes.

Journal: Clinical cornerstone 20080101

Title: Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and rosiglitazone or insulin and acarbose in type 2 diabetes.

Journal: Acta diabetologica 20071201

Title: Acarbose and postprandial hypotension.

Journal: Hypertension (Dallas, Tex. : 1979) 20071101

Title: Acarbose and metabolic control in patients with type 2 diabetes with newly initiated insulin therapy.

Journal: Diabetes, obesity & metabolism 20071101

Title: [A multicenter randomized controlled clinical trial on blood glucose lowering effects of domestic Acarbose (capsule) in type 2 diabetic patients].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20071101

Title: [Adverse effects of alpha-glucosidase inhibitors].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20071028

Title: Who should benefit from the use of alpha-glucosidase inhibitors?

Journal: Current diabetes reports 20071001

Title: Cardiovascular risk factors are reduced with a low dose of acarbose in obese patients with polycystic ovary syndrome.

Journal: Fertility and sterility 20070801

Title: Alpha-glucosidase inhibitors may reduce the risk of type 2 diabetes.

Journal: American family physician 20070801

Title: Oligomeric procyanidins of French maritime pine bark extract (Pycnogenol) effectively inhibit alpha-glucosidase.

Journal: Diabetes research and clinical practice 20070701

Title: Acarbose, an alpha-glucosidase inhibitor, attenuates postprandial hypotension in autonomic failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20070701

Title: Contribution of mucosal maltase-glucoamylase activities to mouse small intestinal starch alpha-glucogenesis.

Journal: The Journal of nutrition 20070701

Title: Low-dose acarbose does not delay digestion of starch but reduces its bioavailability.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20070601

Title: Identification of acceptor substrate binding subsites +2 and +3 in the amylomaltase from Thermus thermophilus HB8.

Journal: Biochemistry 20070501

Title: Comparison of efficacies of a dipeptidyl peptidase IV inhibitor and alpha-glucosidase inhibitors in oral carbohydrate and meal tolerance tests and the effects of their combination in mice.

Journal: Journal of pharmacological sciences 20070501

Title: Reducing the risk of type 2 diabetes: early identification of high-risk individuals and treatment with acarbose.

Journal: Current diabetes reviews 20070501

Title: Rapid diagnosis of late-onset Pompe disease by fluorometric assay of alpha-glucosidase activities in dried blood spots.

Journal: Molecular genetics and metabolism 20070401

Title: Beneficial metabolic effects of nateglinide versus acarbose in patients with newly-diagnosed type 2 diabetes.

Journal: Acta pharmacologica Sinica 20070401

Title: New oral agents for type 2 diabetes.

Journal: Clinical medicine (London, England) 20070401

Title: Glycemic durability of monotherapy for diabetes.

Journal: The New England journal of medicine 20070329

Title: Antidiabetic agents in subjects with mild dysglycaemia: prevention or early treatment of type 2 diabetes?

Journal: Diabetes & metabolism 20070201

Title: Pullulan production by tropical isolates of Aureobasidium pullulans.

Journal: Journal of industrial microbiology & biotechnology 20070101

Title: [Cost-effectiveness of the addition of acarbose to the treatment of patients with type-2 diabetes in Spain].

Journal: Gaceta sanitaria 20070101

Title: Post-marketing surveillance of acarbose treatment in patients with type 2 diabetes mellitus and subjects with impaired glucose tolerance in China.

Journal: Clinical drug investigation 20070101

Title: Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes.

Journal: Cardiovascular diabetology 20070101

Title: [Choroidal vessels alterations in treated and untreated diabetic rats].

Journal: Arquivos brasileiros de oftalmologia 20070101

Title: Reduction of podocytes number in late diabetic alloxan nephropathy: prevention by glycemic control.

Journal: Acta cirurgica brasileira 20070101

Title: Identification and treatment of prediabetes to prevent progression to type 2 diabetes.

Journal: Clinical cornerstone 20070101

Title: [Alpha glucosidase inhibitor].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20061228

Title: Postprandial reactive hypoglycemia in an oldest-old patient effectively treated with low-dose acarbose.

Journal: Endocrine journal 20061201

Title: Antihyperglycaemic and antiperoxidative roles of acarbose in type 2 diabetes mellitus are possibly mediated through changes in thyroid function.

Journal: Clinical and experimental pharmacology & physiology 20061101

Title: Alpha-glucosidase inhibitors for people with impaired glucose tolerance or impaired fasting blood glucose.

Journal: The Cochrane database of systematic reviews 20061018

Title: Blood glucose-lowering activity of colestimide in patients with type 2 diabetes and hypercholesterolemia: a case-control study comparing colestimide with acarbose.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20061001

Title: Alpha-glucosidase inhibitors: new therapeutic agents for chronic heart failure.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20061001

Title: [Postprandial hypoglycemia].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060928

Title: Treating postprandial hyperglycemia does not appear to delay progression of early type 2 diabetes: the Early Diabetes Intervention Program.

Journal: Diabetes care 20060901

Title: Structure of Bacillus halmapalus alpha-amylase crystallized with and without the substrate analogue acarbose and maltose.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060901

Title: Pneumatosis coli induced by acarbose administration for diabetes mellitus. Case report and literature review.

Journal: Minerva gastroenterologica e dietologica 20060901

Title: Oxidative stress in young Zucker rats with impaired glucose tolerance is diminished by acarbose.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901

Title: Postprandial hyperglycaemia and vascular damage--the benefits of acarbose.

Journal: Diabetes & vascular disease research 20060901

Title: Epidemiological data on postprandial glycaemia.

Journal: Diabetes & metabolism 20060901

Title: Single nucleotide polymorphisms of the HNF4alpha gene are associated with the conversion to type 2 diabetes mellitus: the STOP-NIDDM trial.

Journal: Journal of molecular medicine (Berlin, Germany) 20060801

Title: [Effect of yuquan pill on proinflammatory cytokines in patients with type 2 diabetes mellitus].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060801

Title: Acarbose treatment lowers generation and serum concentrations of the protein-bound solute p-cresol: a pilot study.

Journal: Kidney international 20060701

Title: Acarbose improves fibrinolytic activity in patients with impaired glucose tolerance.

Journal: Metabolism: clinical and experimental 20060701

Title: Acarbose ameliorates atherogenecity of low-density lipoprotein in patients with impaired glucose tolerance.

Journal: Metabolism: clinical and experimental 20060701

Title: Combined treatment with exercise training and acarbose improves metabolic control and cardiovascular risk factor profile in subjects with mild type 2 diabetes.

Journal: Diabetes care 20060701

Title: Acarbose in addition to existing treatments in patients with type 2 diabetes: health economic analysis in a German setting.

Journal: Current medical research and opinion 20060701

Title: A review of the economic evidence for acarbose in the prevention of diabetes and cardiovascular events in individuals with impaired glucose tolerance.

Journal: International journal of clinical practice 20060701

Title: Acarbose, an alpha-glucosidase inhibitor, improves endothelial dysfunction in Goto-Kakizaki rats exhibiting repetitive blood glucose fluctuation.

Journal: Biochemical and biophysical research communications 20060630

Title: Nocturnal hypoglycemia in type 1 diabetes: an assessment of preventive bedtime treatments.

Journal: The Journal of clinical endocrinology and metabolism 20060601

Title: Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives.

Journal: The FEBS journal 20060601

Title: A new diagnostic assay for glycogen storage disease type II in mixed leukocytes.

Journal: Molecular genetics and metabolism 20060501

Title: Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain.

Journal: The FEBS journal 20060501

Title: Comparison of maltose and acarbose as inhibitors of maltase-glucoamylase activity in assaying acid alpha-glucosidase activity in dried blood spots for the diagnosis of infantile Pompe disease.

Journal: Genetics in medicine : official journal of the American College of Medical Genetics 20060501

Title: The use of acarbose inhibition in the measurement of acid alpha-glucosidase activity in blood lymphocytes for the diagnosis of Pompe disease.

Journal: Genetics in medicine : official journal of the American College of Medical Genetics 20060501

Title: Effect of inhibition of alpha-glucosidase on age-related glucose intolerance and pancreatic atrophy in rats.

Journal: Metabolism: clinical and experimental 20060401

Title: Combination therapy for postprandial and orthostatic hypotension in an elderly patient with type 2 diabetes mellitus.

Journal: Journal of the American Geriatrics Society 20060401

Title: Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: a randomized crossover study.

Journal: The Journal of clinical endocrinology and metabolism 20060301

Title: Postprandial hyperglycaemia and cardiovascular disease.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20060301

Title: Effect of acarbose on alanine aminotransferase and aspartate aminotransferase activities in the liver of control and diabetic CBA mice.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20060301

Title: Effects of okchun-san, a herbal formulation, on blood glucose levels and body weight in a model of Type 2 diabetes.

Journal: Journal of ethnopharmacology 20060220

Title: Cardiovascular benefits of acarbose in impaired glucose tolerance and type 2 diabetes.

Journal: International journal of cardiology 20060208

Title: Identifying the impact of diabetes research.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20060201

Title: Hepatotoxicity associated with acarbose therapy.

Journal: The Annals of pharmacotherapy 20060101

Title: [Prevention of the manifestation of diabetes in the elderly in the presymptomatic stage].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20060101

Title: Should postprandial hyperglycaemia in prediabetic and type 2 diabetic patients be treated?

Journal: Drugs 20060101

Title: [Glucose control in cardiac disease].

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20060101

Title: Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101

Title: Treatment of impaired glucose tolerance with acarbose and its effect on intima-media thickness: a substudy of the STOP-NIDDM trial (study to prevent non-insulin-dependent diabetes mellitus).

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101

Title: Pharmacological and surgical intervention for the prevention of diabetes.

Journal: Nestle Nutrition workshop series. Clinical & performance programme 20060101

Title: [Probability of control of the patient with diabetes exclusively treated with pharmacological therapy].

Journal: Revista medica del Instituto Mexicano del Seguro Social 20060101

Title: Effective BP control, aspirin use and emphasis on post-prandial glucose control: Cornerstones of modern CV risk management.

Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20060101

Title: Acarbose, an alpha-glucosidase inhibitor, decreases aortic gene expression and serum levels of monocyte chemoattractant protein-1 in fructose-fed rats.

Journal: The Journal of international medical research 20060101

Title: Synergistic effect of doxazosin and acarbose in improving metabolic control in patients with impaired glucose tolerance.

Journal: Clinical drug investigation 20060101

Title: Postmarketing surveillance of acarbose treatment in Taiwanese patients with type 2 diabetes mellitus.

Journal: Clinical drug investigation 20060101

Title: [Revised blood pressure goals and no elevated glucose readings in between].

Journal: MMW Fortschritte der Medizin 20051215

Title: The significance of gut sucrase activity for osmoregulation in the pea aphid, Acyrthosiphon pisum.

Journal: Journal of insect physiology 20051201

Title: Acarbose attenuates the hypotensive response to sucrose and slows gastric emptying in the elderly.

Journal: The American journal of medicine 20051101

Title: Drug therapy in prediabetes.

Journal: Journal of the Indian Medical Association 20051101

Title: Prevention of type 2 diabetes in the prediabetic population.

Journal: Journal of the Indian Medical Association 20051101

Title: Cost-effectiveness of acarbose for the management of impaired glucose tolerance in Sweden.

Journal: International journal of clinical practice 20051001

Title: Effect of different phenolic compounds on alpha-amylase activity: screening by microplate-reader based kinetic assay.

Journal: Die Pharmazie 20051001

Title: Insulin in type 2 diabetes: a useful alternative despite limited assessment based on surrogate endpoints.

Journal: Prescrire international 20051001

Title: Oligosaccharide binding to barley alpha-amylase 1.

Journal: The Journal of biological chemistry 20050923

Title: Characterization of maltose and maltotriose transport in the acarbose-producing bacterium Actinoplanes sp.

Journal: Research in microbiology 20050901

Title: Modeling protein recognition of carbohydrates.

Journal: Proteins 20050901

Title: Acarbose in obese patients with polycystic ovarian syndrome: a double-blind, randomized, placebo-controlled study.

Journal: Human reproduction (Oxford, England) 20050901

Title: Reduction of postchallenge hyperglycaemia prevents acute endothelial dysfunction in subjects with impaired glucose tolerance.

Journal: European journal of clinical investigation 20050901

Title: Drugs for diabetes.

Journal: Treatment guidelines from the Medical Letter 20050801

Title: Identification of impurities in acarbose by using an integrated liquid chromatography-nuclear magnetic resonance and liquid chromatography-mass spectrometry approach.

Journal: Journal of separation science 20050801

Title: [The change of atherogenic index of plasma (AIP) level in type 2 diabetic pedigrees and the response of AIP to Acarbose or Glimepiride in therapy of type 2 diabetes mellitus].

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20050601

Title: Antidiabetic drug utilization in hungary.

Journal: Pharmacy world & science : PWS 20050601

Title: Treatments and devices for future diabetes management.

Journal: Nursing times 20050501

Title: Prevention of type 2 diabetes.

Journal: Current molecular medicine 20050501

Title: [Therapy with oral antidiabetic agents -- special considerations in the case of coronary heart disease].

Journal: Deutsche medizinische Wochenschrift (1946) 20050429

Title: Alpha-glucosidase inhibitors for type 2 diabetes mellitus.

Journal: The Cochrane database of systematic reviews 20050418

Title: Repetitive postprandial hyperglycemia increases cardiac ischemia/reperfusion injury: prevention by the alpha-glucosidase inhibitor acarbose.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050401

Title: Acarbose in the prevention of cardiovascular disease in subjects with impaired glucose tolerance and type 2 diabetes mellitus.

Journal: Current opinion in pharmacology 20050401

Title: alpha-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7-36 amide) and to delay gastric emptying in Type 2 diabetic patients.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050401

Title: The acbH gene of Actinoplanes sp. encodes a solute receptor with binding activities for acarbose and longer homologs.

Journal: Research in microbiology 20050401

Title: The effects of acarbose and Rumex patientia L. on ultrastructural and biochemical changes of pancreatic B cells in streptozotocin-induced diabetic rats.

Journal: Journal of ethnopharmacology 20050321

Title: Acarbose rearrangement mechanism implied by the kinetic and structural analysis of human pancreatic alpha-amylase in complex with analogues and their elongated counterparts.

Journal: Biochemistry 20050308

Title: Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase.

Journal: Protein science : a publication of the Protein Society 20050301

Title: The common polymorphisms (single nucleotide polymorphism [SNP] +45 and SNP +276) of the adiponectin gene predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.

Journal: Diabetes 20050301

Title: Effect of two alpha-glucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms.

Journal: Metabolism: clinical and experimental 20050301

Title: [Specific aspects of diabetes management in the elderly].

Journal: MMW Fortschritte der Medizin 20050217

Title: Acarbose attenuates hypoglycemia from dumping syndrome in an elderly man with gastrectomy.

Journal: Journal of the American Geriatrics Society 20050201

Title: Structure of a Bacillus halmapalus family 13 alpha-amylase, BHA, in complex with an acarbose-derived nonasaccharide at 2.1 A resolution.

Journal: Acta crystallographica. Section D, Biological crystallography 20050201

Title: Acarbose treatment in liver disease: cognitive or glycemic control?

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20050201

Title: A randomized controlled trial of acarbose in hepatic encephalopathy.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20050201

Title: [Pathophysiological conditions progressing from impaired glucose tolerance: atherosclerosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Pathophysiological conditions progressing from impaired glucose tolerance: coronary artery disease (ischemic heart disease)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Impaired glucose tolerance in dumping syndrome].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Selection of oral antidiabetic drugs].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Effects of acarbose, alpha-glucosidase inhibitor in treatment of impaired glucose tolerance].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [The Study TO Prevent Non-Insulin Dependent Diabetes Mellitus trial (acarbose)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Therapies for newly-onset diabetic patients].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: [Treatment for coronary artery disease patients with impaired glucose tolerance].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201

Title: Oral antihyperglycemic therapy for type 2 diabetes mellitus.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050118

Title: Comparison of the effects of acarbose and metformin use on ovulation rates in clomiphene citrate-resistant polycystic ovary syndrome.

Journal: Human reproduction (Oxford, England) 20050101

Title: Pharmacologic prevention or delay of type 2 diabetes mellitus.

Journal: The Annals of pharmacotherapy 20050101

Title: Post-prandial hyperglycaemia and prevention of cardiovascular disease.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050101

Title: [Comparative study among five different treatments on the clinical and laboratory changes in rats with alloxan-induced diabetes].

Journal: Acta cirurgica brasileira 20050101

Title: Inhibition of postprandial hyperglycemia by acarbose is a promising therapeutic strategy for the treatment of patients with the metabolic syndrome.

Journal: Medical hypotheses 20050101

Title: Acarbose is a promising therapeutic strategy for the treatment of patients with nonalcoholic steatohepatitis (NASH).

Journal: Medical hypotheses 20050101

Title: A new method for production of valienamine with microbial degradation of acarbose.

Journal: Biotechnology progress 20050101

Title: [Acarbose for the treatment of impared glucose tolerance?].

Journal: Gaceta sanitaria 20050101

Title: In vitro and in vivo inhibition of alpha-amylases of stored-product mite Acarus siro.

Journal: Experimental & applied acarology 20050101

Title: Acarbose, an alpha-glucosidase inhibitor, improves insulin resistance in fructose-fed rats.

Journal: Drugs under experimental and clinical research 20050101

Title: Perinatal outcomes and the use of oral hypoglycemic agents.

Journal: Journal of perinatal medicine 20050101

Title: Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial.

Journal: Diabetologia 20041201

Title: Postprandial hypotension treated with acarbose in a patient with type 1 diabetes mellitus.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20041201

Title: [Effects of acarbose on amylase tests].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20041201

Title: Effects of acarbose in patients with beta-thalassaemia major and abnormal glucose homeostasis.

Journal: Pediatric endocrinology reviews : PER 20041201

Title: Effects of acarbose in beta-thalassaemia major patients with normal glucose tolerance and hyperinsulinism.

Journal: Pediatric endocrinology reviews : PER 20041201

Title: In situ extension as an approach for identifying novel alpha-amylase inhibitors.

Journal: The Journal of biological chemistry 20041112

Title: Effect of lowering postprandial hyperglycemia on insulin secretion in older people with impaired glucose tolerance.

Journal: American journal of physiology. Endocrinology and metabolism 20041101

Title: Economic evaluation of therapeutic interventions to prevent Type 2 diabetes in Canada.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20041101

Title: The role of alpha-amylase in the perception of oral texture and flavour in custards.

Journal: Physiology & behavior 20041030

Title: Single amino acid mutations interchange the reaction specificities of cyclodextrin glycosyltransferase and the acarbose-modifying enzyme acarviosyl transferase.

Journal: Biochemistry 20041019

Title: Effect of acarbose treatment on the risk of silent myocardial infarctions in patients with impaired glucose tolerance: results of the randomised STOP-NIDDM trial electrocardiography substudy.

Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20041001

Title: Acarbose lowers serum triglyceride and postprandial chylomicron levels in type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20040901

Title: Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NF-kappaB activation in PBMCs.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040901

Title: Endothelial dysfunction, inflammation and diabetes.

Journal: Reviews in endocrine & metabolic disorders 20040801

Title: Computer-aided molecular design of novel glucosidase inhibitors for AIDS treatment.

Journal: Journal of biomolecular structure & dynamics 20040801

Title: The genome of phiAsp2, an actinoplanes infecting phage.

Journal: Virus genes 20040801

Title: Isolation and characterization of a novel intracellular glucosyltransferase from the acarbose producer Actinoplanes sp. CKD485-16.

Journal: Applied microbiology and biotechnology 20040801

Title: Complex structures of Thermoactinomyces vulgaris R-47 alpha-amylase 2 with acarbose and cyclodextrins demonstrate the multiple substrate recognition mechanism.

Journal: The Journal of biological chemistry 20040723

Title: Increased platelet activation in young Zucker rats with impaired glucose tolerance is improved by acarbose.

Journal: Thrombosis and haemostasis 20040701

Title: No evidence for a reduction of myocardial infarctions by acarbose.

Journal: European heart journal 20040701

Title: Response to Chiasson et al.: Acarbose for the prevention of Type 2 diabetes, hypertension and cardiovascular disease in subjects with impaired glucose tolerance: facts and interpretations concerning the critical analysis of the STOP-NIDDM Trial data.

Journal: Diabetologia 20040601

Title: Acarbose for the prevention of Type 2 diabetes, hypertension and cardiovascular disease in subjects with impaired glucose tolerance: facts and interpretations concerning the critical analysis of the STOP-NIDDM Trial data.

Journal: Diabetologia 20040601

Title: The addition of acarbose to insulin lispro reduces acute glycaemic responses in patients with type-2 diabetes.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040601

Title: [Primary prevention of diabetes mellitus type 2].

Journal: Der Internist 20040601

Title: Modification of beta-cell response to different postprandial blood glucose concentrations by prandial repaglinide and combined acarbose/repaglinide application.

Journal: Diabetes, nutrition & metabolism 20040601

Title: [Cardioprotection by acarbose--pro].

Journal: Deutsche medizinische Wochenschrift (1946) 20040514

Title: [Cardioprotection by acarbose--contra].

Journal: Deutsche medizinische Wochenschrift (1946) 20040514

Title: alpha-Glucosidase inhibitory activity of some Sri Lanka plant extracts, one of which, Cassia auriculata, exerts a strong antihyperglycemic effect in rats comparable to the therapeutic drug acarbose.

Journal: Journal of agricultural and food chemistry 20040505

Title: Acarbose slows progression of intima-media thickness of the carotid arteries in subjects with impaired glucose tolerance.

Journal: Stroke 20040501

Title: Primary prevention of type 2 diabetes: how do we do it?

Journal: The Israel Medical Association journal : IMAJ 20040501

Title: [Clinical observation on improving senile postprandial hyperglycemia and insulin sensitivity with combination of acarbose and liuwei nengxiao capsule].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040501

Title: [Cost-effective analysis of preventive treatment on diabetes].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20040501

Title: Two potent competitive inhibitors discriminating alpha-glucosidase family I from family II.

Journal: Carbohydrate research 20040428

Title: Combined use of liquid chromatography-nuclear magnetic resonance spectroscopy and liquid chromatography-mass spectrometry for the characterization of an acarbose degradation product.

Journal: Journal of chromatography. A 20040416

Title: [Reactive hypoglycaemia, a mysterious, insidious but non dangerous critical phenomenon].

Journal: Revue medicale de Liege 20040401

Title: [Prevention by life style intervention and medication. To run away from type 2 diabetes].

Journal: MMW Fortschritte der Medizin 20040401

Title: Acarbose attenuates experimental non-alcoholic steatohepatitis.

Journal: Biochemical and biophysical research communications 20040312

Title: Acarbose for prevention of diabetes, hypertension and cardiovascular events? A critical analysis of the STOP-NIDDM data.

Journal: Diabetologia 20040301

Title: Starch digestion, large-bowel fermentation and intestinal mucosal cell proliferation in rats treated with the alpha-glucosidase inhibitor acarbose.

Journal: The British journal of nutrition 20040301

Title: Biotechnology and molecular biology of the alpha-glucosidase inhibitor acarbose.

Journal: Applied microbiology and biotechnology 20040201

Title: Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site.

Journal: Protein science : a publication of the Protein Society 20040201

Title: Coefficient of beta-cell failure in patients with type 2 diabetes treated with pioglitazone or acarbose.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20040201

Title: [Late diagnosis. Only after infarct is diabetes detected].

Journal: MMW Fortschritte der Medizin 20040129

Title: Acarbose reduces the risk for myocardial infarction in type 2 diabetic patients: meta-analysis of seven long-term studies.

Journal: European heart journal 20040101

Title: The effect of acarbose on insulin resistance in obese hypertensive subjects with normal glucose tolerance: a randomized controlled study.

Journal: Diabetes, obesity & metabolism 20040101

Title: Is acarbose equivalent to tolbutamide as first treatment for newly diagnosed type 2 diabetes in general practice? A randomised controlled trial.

Journal: Diabetes research and clinical practice 20040101

Title: Different effects of two alpha-glucosidase inhibitors, acarbose and voglibose, on serum 1,5-anhydroglucitol (1,5AG) level.

Journal: Journal of diabetes and its complications 20040101

Title: [Cost-effectiveness analysis of acarbose in the treatment of patients with impaired glucose tolerance].

Journal: Gaceta sanitaria 20040101

Title: [Continuation 50. Type 2 diabetes: possibilities and limitations of pharmacological therapy].

Journal: MMW Fortschritte der Medizin 20031218

Title: Acarbose for patients with hypertension and impaired glucose tolerance.

Journal: JAMA 20031217

Title: Acarbose for patients with hypertension and impaired glucose tolerance.

Journal: JAMA 20031217

Title: Acarbose for patients with hypertension and impaired glucose tolerance.

Journal: JAMA 20031217

Title: Acarbose for patients with hypertension and impaired glucose tolerance.

Journal: JAMA 20031217

Title: [Modern strategies of infarction prevention in hypertensives and diabetics. Salt and sugar -- both are risky for the heart].

Journal: MMW Fortschritte der Medizin 20031211

Title: Acarbose for the prevention of diabetes.

Journal: Cleveland Clinic journal of medicine 20031201

Title: Acarbose for the prevention of diabetes.

Journal: Cleveland Clinic journal of medicine 20031201

Title: [The use of oral antidiabetic drugs in the treatment of polycystic ovary syndrome].

Journal: Zentralblatt fur Gynakologie 20031201

Title: Effects of essential carbohydrate/aromatic stacking interaction with Tyr100 and Phe259 on substrate binding of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp. 1011.

Journal: Journal of biochemistry 20031201

Title: [Progress in the prevention of type 2 diabetes].

Journal: Wiener klinische Wochenschrift 20031128

Title: A new synthesis of the oligosaccharide domain of acarbose.

Journal: Carbohydrate research 20031121

Title: Detailed dissection of a new mechanism for glycoside cleavage: alpha-1,4-glucan lyase.

Journal: Biochemistry 20031111

Title: [Acarbose, a reliable therapeutic principle].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: [Postprandial blood glucose as the driving force in pathogenesis of type 2 diabetes].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: [Does targeted therapy of type 2 diabetes prevent cardiovascular incidents?].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: [From cardiovascular risk to chronic heart failure].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: [Awards for research and development of acarbose].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: [Diabetes mellitus, cardiovascular sequelae and acarbose. Introductory Address by the German Diabetes Society].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: [Prevention and early therapy play too minor a role in our health care system].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20031015

Title: On the mechanism of alpha-amylase.

Journal: European journal of biochemistry 20031001

Title: Review of acarbose therapeutic strategies in the long-term treatment and in the prevention of type 2 diabetes.

Journal: International journal of clinical pharmacology and therapeutics 20031001

Title: [Is type-2 diabetes mellitus preventable?].

Journal: Orvosi hetilap 20030928

Title: Biosynthetic studies on the alpha-glucosidase inhibitor acarbose: the chemical synthesis of isotopically labeled 2-epi-5-epi-valiolone analogs.

Journal: Carbohydrate research 20030926

Title: Study of the inhibition of four alpha amylases by acarbose and its 4IV-alpha-maltohexaosyl and 4IV-alpha-maltododecaosyl analogues.

Journal: Carbohydrate research 20030910

Title: [Dangerous blood glucose peaks. Vascular damage even before diabetes].

Journal: MMW Fortschritte der Medizin 20030904

Title: Failure of acarbose in preventing bacterial translocation in experimental cirrhosis.

Journal: Journal of hepatology 20030901

Title: Efficacy of acarbose in Chinese subjects with impaired glucose tolerance.

Journal: Diabetes research and clinical practice 20030901

Title: Short-term effect of acarbose on specific intestinal disaccharidase activities and hyperglycaemia in CBA diabetic mice.

Journal: Journal of animal physiology and animal nutrition 20030801

Title: The structure of barley alpha-amylase isozyme 1 reveals a novel role of domain C in substrate recognition and binding: a pair of sugar tongs.

Journal: Structure (London, England : 1993) 20030801

Title: Is there a role for metformin or acarbose as a weight-loss agent in the absence of diabetes?

Journal: Cleveland Clinic journal of medicine 20030801

Title: Prospective multicentre trial comparing the efficacy of, and compliance with, glimepiride or acarbose treatment in patients with type 2 diabetes not controlled with diet alone.

Journal: Diabetes, nutrition & metabolism 20030801

Title: Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial.

Journal: JAMA 20030723

Title: [Pharmacological treatment of postprandial hyperglycemia in hypertensive patients with type 2 diabetes mellitus].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030701

Title: [Coronary disease -- risk factors to be controlled aggressively. Sweet hearts of women are especially endangered].

Journal: MMW Fortschritte der Medizin 20030612

Title: Treatment of feline diabetes mellitus using an alpha-glucosidase inhibitor and a low-carbohydrate diet.

Journal: Journal of feline medicine and surgery 20030601

Title: [Is it possible to prevent type 2 diabetes?].

Journal: Annales d'endocrinologie 20030601

Title: Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor.

Journal: The Journal of biological chemistry 20030523

Title: Acarbose improves glycemic control in insulin-treated Asian type 2 diabetic patients: results from a multinational, placebo-controlled study.

Journal: Diabetes research and clinical practice 20030501

Title: Treatment for hyperglycemia promotes pancreatic regeneration in rats without CCK-1 receptor gene expression.

Journal: Pancreas 20030501

Title: The effects of conjugated linoleic acids or an alpha-glucosidase inhibitor on tissue lipid concentrations and fatty acid composition of broiler chicks fed a low-protein diet.

Journal: Poultry science 20030501

Title: Type 2 diabetes express highway, where is the 'U' turn?

Journal: The Journal of the Association of Physicians of India 20030501

Title: The acarbose-biosynthetic enzyme AcbO from Actinoplanes sp. SE 50/110 is a 2-epi-5-epi-valiolone-7-phosphate 2-epimerase.

Journal: FEBS letters 20030410

Title: Identification of a 1-epi-valienol 7-kinase activity in the producer of acarbose, Actinoplanes sp. SE50/110.

Journal: FEBS letters 20030410

Title: [Acute generalized exanthematous pustulosis induced by drugs with low-digestive absorption: acarbose and nystatin].

Journal: Annales de dermatologie et de venereologie 20030401

Title: [Acarbose for prevention of diabetes mellitus. STOP-NIDDM]].

Journal: Der Internist 20030401

Title: Differential regulation of a hyperthermophilic alpha-amylase with a novel (Ca,Zn) two-metal center by zinc.

Journal: The Journal of biological chemistry 20030314

Title: Crystal structure and evolution of a prokaryotic glucoamylase.

Journal: Journal of molecular biology 20030314

Title: [Therapy decision based on the glucose triad. Drug treatment of type 2 diabetes].

Journal: MMW Fortschritte der Medizin 20030227

Title: [Robert Koch Award for acarbose. Antidiabetic drug prevents myocardial infarct].

Journal: MMW Fortschritte der Medizin 20030206

Title: Acarbose improves glycemic control in overweight type 2 diabetic patients insufficiently treated with metformin.

Journal: Diabetes care 20030201

Title: The C7N aminocyclitol family of natural products.

Journal: Natural product reports 20030201

Title: Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase.

Journal: Journal of molecular biology 20030131

Title: [Acarbose can slow down beginning of type 2 diabetes].

Journal: Deutsche medizinische Wochenschrift (1946) 20030124

Title: [Already in altered glucose tolerance an antidiabetic drug. Significantly fewer heart attacks].

Journal: MMW Fortschritte der Medizin 20030123

Title: Acarbose in the treatment of elderly patients with type 2 diabetes.

Journal: Diabetes research and clinical practice 20030101

Title: Thermoanaerobacterium thermosulfurigenes cyclodextrin glycosyltransferase.

Journal: European journal of biochemistry 20030101

Title: Influence of treatment with acarbose or glibenclamide on insulin sensitivity in type 2 diabetic patients.

Journal: Diabetes, obesity & metabolism 20030101

Title: Is there a role for alpha-glucosidase inhibitors in the prevention of type 2 diabetes mellitus?

Journal: Drugs 20030101

Title: [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20030101

Title: Efficacy and tolerability of acarbose in Asian patients with type 2 diabetes inadequately controlled with diet and sulfonylureas.

Journal: Journal of diabetes and its complications 20030101

Title: Acarbose treatment of infant dumping syndrome: extensive study of glucose dynamics and long-term follow-up.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20030101

Title: Acarbose and idiopathic reactive hypoglycemia.

Journal: Hormone research 20030101

Title: [Acarbose--an effective drug for the prevention of type 2 diabetes and cardiovascular diseases?].

Journal: Duodecim; laaketieteellinen aikakauskirja 20030101

Title: Reduced formation of byproduct component C in acarbose fermentation by Actinoplanes sp. CKD485-16.

Journal: Biotechnology progress 20030101

Title: [From control of impaired carbohydrate tolerance to primary prevention of atherosclerosis. Encouraging results of the STOP-NIDDM trial].

Journal: Kardiologiia 20030101

Title: A novel method for the assay of alpha-glucosidase inhibitory activity using a multi-channel oxygen sensor.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20021201

Title: Prevention of type 2 diabetes.

Journal: The Malaysian journal of pathology 20021201

Title: Synthesis of acarbose analogues by transglycosylation reactions of Leuconostoc mesenteroides B-512FMC and B-742CB dextransucrases.

Journal: Carbohydrate research 20021129

Title: Acarbose for type 2 diabetes prevention.

Journal: Lancet (London, England) 20021109

Title: Acarbose for type 2 diabetes prevention.

Journal: Lancet (London, England) 20021109

Title: Functional mimicry between anti-Tendamistat antibodies and alpha-amylase.

Journal: Journal of immunological methods 20021101

Title: Barley alpha-amylase Met53 situated at the high-affinity subsite -2 belongs to a substrate binding motif in the beta-->alpha loop 2 of the catalytic (beta/alpha)8-barrel and is critical for activity and substrate specificity.

Journal: European journal of biochemistry 20021101

Title: Isolation, characterization and inhibition by acarbose of the alpha-amylase from Lactobacillus fermentum: comparison with Lb. manihotivorans and Lb. plantarum amylases.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20021101

Title: [A case of pneumatosis cystoides intestinalis assumed to be induced by acarbose administration for diabetes mellitus and pemphigus vulgaris].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20021101

Title: [In high risk for diabetes should drugs be used for prevention? (interview by Dr. Judith Neumaier)].

Journal: MMW Fortschritte der Medizin 20021003

Title: Do therapeutic doses of acarbose alter the pharmacokinetics of digoxin?

Journal: The Israel Medical Association journal : IMAJ 20021001

Title: [Combination therapy with biguanides].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021001

Title: [Sports, diet, acarbose. Delaying the onset of diabetes].

Journal: MMW Fortschritte der Medizin 20020926

Title: [Primary prevention of diabetes mellitus by pharmacological intervention].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [Adverse effects of oral hypoglycemic agents].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [Metformin--its regimen and effects].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [alpha-Glucosidase inhibitor, its structure and mechanism of antidiabetic action].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [Indication and side effect of alpha glucosidase inhibitor].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [Combination therapy with insulin and alpha-glucosidase inhibitor].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [Efficacy of combination therapy of alpha-glucosidase inhibitor and insulin sensitizer in patients with type 2 diabetes].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020901

Title: [Study with alpha-glucosidase inhibitor proves: diabetes can be delayed].

Journal: MMW Fortschritte der Medizin 20020822

Title: Crystal structure of Thermotoga maritima 4-alpha-glucanotransferase and its acarbose complex: implications for substrate specificity and catalysis.

Journal: Journal of molecular biology 20020802

Title: Improved glycemic control by acarbose therapy in hypertensive diabetic patients: effects on blood pressure and hormonal parameters.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020801

Title: A novel amylolytic enzyme from Thermotoga maritima, resembling cyclodextrinase and alpha-glucosidase, that liberates glucose from the reducing end of the substrates.

Journal: Biochemical and biophysical research communications 20020726

Title: Preparation and characterization of alpha-D-glucopyranosyl-alpha-acarviosinyl-D-glucopyranose, a novel inhibitor specific for maltose-producing amylase.

Journal: Biochemistry 20020723

Title: Oral hypoglycaemics. When not to use what.

Journal: Australian family physician 20020701

Title: No sizable inhibition of glucose-induced insulin secretion by acarbose and castanospermine.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020701

Title: Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway.

Journal: The Journal of biological chemistry 20020621

Title: Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial.

Journal: Lancet (London, England) 20020615

Title: Early acarbose treatment ameliorates resistance of insulin-regulated GLUT4 trafficking in obese Zucker rats.

Journal: European journal of pharmacology 20020607

Title: Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and acarbose).

Journal: The American journal of cardiology 20020601

Title: Acarbose improves indirectly both insulin resistance and secretion in obese type 2 diabetic patients.

Journal: Diabetes & metabolism 20020601

Title: The effect of combination treatment with acarbose and glibenclamide on postprandial glucose and insulin profiles: additive blood glucose lowering effect and decreased hypoglycaemia.

Journal: Diabetes, nutrition & metabolism 20020601

Title: Modification of ascorbic acid using transglycosylation activity of Bacillus stearothermophilus maltogenic amylase to enhance its oxidative stability.

Journal: Journal of agricultural and food chemistry 20020522

Title: [Even if fasting blood glucose value is quite normal, proceed with a glucose tolerance test].

Journal: MMW Fortschritte der Medizin 20020516

Title: Glucagon-like peptide-1 response to acarbose in elderly type 2 diabetic subjects.

Journal: Diabetes research and clinical practice 20020501

Title: Novel alpha-glucosidase inhibitors, CKD-711 and CKD-711a produced by Streptomyces sp. CK-4416. II. Biological properties.

Journal: The Journal of antibiotics 20020501

Title: [Metformin. Mode of action and effect of monotherapy and combination therapy on glucose metabolism in type 2 diabetes].

Journal: Ugeskrift for laeger 20020408

Title: Addition of maltodextrins to the nonreducing-end of acarbose by reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase.

Journal: Carbohydrate research 20020315

Title: Different effects of acarbose and glibenclamide on proinsulin and insulin profiles in people with Type 2 diabetes.

Journal: Diabetes research and clinical practice 20020301

Title: Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes.

Journal: Clinical science (London, England : 1979) 20020301

Title: Acarbose related diarrhea: increased butyrate upregulates prostaglandin E.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020301

Title: [Type 2 diabetes. How can the infarction risk be reduced?].

Journal: MMW Fortschritte der Medizin 20020227

Title: Biosynthetic studies on the alpha-glucosidase inhibitor acarbose: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-alpha-D-glucose.

Journal: Carbohydrate research 20020218

Title: Efficacy and safety of voglibose in comparison with acarbose in type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20020201

Title: The effect of acarbose on the colonic transit time of elderly long-term care patients with type 2 diabetes mellitus.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20020201

Title: Catalytic activities of intracellular dimeric neopullulanase on cyclodextrin, acarbose and maltose.

Journal: Biotechnology and applied biochemistry 20020201

Title: Impaired glucose homeostasis in young adult thalassemic patients: a pilot study with acarbose.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20020201

Title: Chronic acarbose-feeding increases GLUT1 protein without changing intestinal glucose absorption function.

Journal: European journal of pharmacology 20020111

Title: Pharmacokinetics, tolerability, and fructosamine-lowering effect of a novel, controlled-release formulation of alpha-lipoic acid.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101

Title: [Reducing postprandial glucose levels. Glucosidase antagonists].

Journal: Pharmazie in unserer Zeit 20020101

Title: Inhibition of catalytic and glucan-binding activities of a streptococcal GTF forming insoluble glucans.

Journal: Caries research 20020101

Title: [Optimal drug therapy of glucose intolerance is a guarantee of successful prevention of type 2 diabetes mellitus].

Journal: Terapevticheskii arkhiv 20020101

Title: The effects of acarbose and Rumex patientia on liver ultrastructure in streptozotocin-induced diabetic (type II) rats.

Journal: Drugs under experimental and clinical research 20020101

Title: Improved glycemic control and lipid profile in a randomized study of pioglitazone compared with acarbose in patients with type 2 diabetes mellitus.

Journal: Treatments in endocrinology 20020101

Title: Acarbose treatment of postprandial hypoglycemia in children after Nissen fundoplication.

Journal: The Journal of pediatrics 20011201

Title: Effect of acarbose on weight maintenance after dietary weight loss in obese subjects.

Journal: Diabetes, obesity & metabolism 20011201

Title: [Some considerations on the Consensus of the Spanish Diabetes Society and the Spanish Society of Family and Community Medicine on the criteria and guidelines for combined therapy for type 2 diabetes].

Journal: Atencion primaria 20011130

Title: The possible association of in vivo leukocyte-platelet heterophilic aggregate formation and the development of diabetic angiopathy.

Journal: Platelets 20011101

Title: [Thus to avoid complications of diabetes. To combine early].

Journal: MMW Fortschritte der Medizin 20011101

Title: Clinical, endocrine and metabolic effects of acarbose, an alpha-glucosidase inhibitor, in PCOS patients with increased insulin response and normal glucose tolerance.

Journal: Human reproduction (Oxford, England) 20011001

Title: [Info-Meeting. Pharmacologic prevention of the progression from impaired glucose tolerance to type 2 diabetes: favorable effects of metformin and acarbose].

Journal: Revue medicale de Liege 20011001

Title: Acarbose-induced liver injury in an anti-hepatitis C virus positive patient.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20011001

Title: [Acute hepatitis induced by acarbose].

Journal: Medicina clinica 20010922

Title: Inhibition of gastric emptying by acarbose is correlated with GLP-1 response and accompanied by CCK release.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010901

Title: Exercise adds to metformin and acarbose efficacy in db/db mice.

Journal: Metabolism: clinical and experimental 20010901

Title: A case of glycogen storage disease IA with multiple hepatic tumors managed by transcatheter arterial embolization and an acarbose diet.

Journal: Journal of pediatric gastroenterology and nutrition 20010901

Title: Use of an alpha-glucosidase inhibitor to maintain glucose homoeostasis during postprandial exercise in intensively treated Type 1 diabetic subjects.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20010901

Title: Effects of chronic treatment with acarbose on glucose and lipid metabolism in obese diabetic Wistar rats.

Journal: Diabetes, obesity & metabolism 20010801

Title: Chemoenzymatic synthesis of 2-chloro-4-nitrophenyl beta-maltoheptaoside acceptor-products using glycogen phosphorylase b.

Journal: Carbohydrate research 20010703

Title: TPN-evoked dysfunction of islet lysosomal activity mediates impairment of glucose-stimulated insulin release.

Journal: American journal of physiology. Endocrinology and metabolism 20010701

Title: A new era in type 2 diabetes mellitus treatment?

Journal: The American journal of medicine 20010701

Title: Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High-resolution structural analysis of an enzyme-inhibitor complex.

Journal: Biochemistry 20010626

Title: Safety and efficacy of acarbose in the treatment of Type 2 diabetes: data from a 5-year surveillance study.

Journal: Diabetes research and clinical practice 20010601

Title: Type 2 diabetes. How new insights, new drugs are changing clinical practice.

Journal: Geriatrics 20010601

Title: Insulinoma, type 2 diabetes and plasminogen activator inhibitor type-I.

Journal: Coronary artery disease 20010601

Title: Effect of 'antidiabetis' herbal preparation on serum glucose and fructosamine in NOD mice.

Journal: Journal of ethnopharmacology 20010501

Title: The effect of acarbose on the pharmacokinetics of rosiglitazone.

Journal: European journal of clinical pharmacology 20010501

Title: [Acarbose and diabetes mellitus. Practical implications].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20010501

Title: [Changes in metabolic parameters and microalbuminuria in patients with type 2 diabetes treated with acarbose].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20010501

Title: Predictors of persistence of use of the novel antidiabetic agent acarbose.

Journal: Archives of internal medicine 20010423

Title: [Type 2 diabetes. Acarbose interrupts the vicious circle].

Journal: MMW Fortschritte der Medizin 20010405

Title: Crystal structure of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011 complexed with 1-deoxynojirimycin at 2.0 A resolution.

Journal: Journal of biochemistry 20010401

Title: Inhibition of beta-glycosidases by acarbose analogues containing cellobiose and lactose structures.

Journal: Carbohydrate research 20010309

Title: Inhibitory effect and mechanism of acarbose combined with gymnemic acid on maltose absorption in rat intestine.

Journal: World journal of gastroenterology 20010215

Title: Reactive hypoglycaemia due to late dumping syndrome: successful treatment with acarbose.

Journal: Swiss medical weekly 20010210

Title: Ileus after administration of cold remedy in an elderly diabetic patient treated with acarbose.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20010201

Title: Effect of treatment with acarbose and insulin in patients with non-insulin-dependent diabetes mellitus associated with non-alcoholic liver cirrhosis.

Journal: Diabetes, obesity & metabolism 20010201

Title: Comparison of acarbose and gliclazide as first-line agents in patients with type 2 diabetes.

Journal: Current medical research and opinion 20010101

Title: Acarbose improved severe postprandial hypotension in a patient with diabetes mellitus.

Journal: Journal of diabetes and its complications 20010101

Title: [Current approaches to treatment of secondary sulfonylamide drug resistance in Type II diabetes mellitus].

Journal: Likars'ka sprava 20010101

Title: Secretion of GIP in responders to acarbose in obese Type 2(NIDDM) patients.

Journal: Journal of diabetes and its complications 20010101

Title: The biosynthesis of acarbose and validamycin.

Journal: Chemical record (New York, N.Y.) 20010101

Title: [Acarbose-induced acute hepatitis. Report of two events in the same patient].

Journal: Gastroenterologia y hepatologia 20000101

Title: Piroxicam and acarbose as chemopreventive agents for spontaneous intestinal adenomas in APC gene 1309 knockout mice.

Journal: Japanese journal of cancer research : Gann 19980401

Title: Acarbose reduces blood pressure in sucrose-induced hypertension in rats.

Journal: Israel journal of medical sciences 19970301

Title: Formation of acarbose phosphate by a cell-free extract from the acarbose producer Actinoplanes sp.

Journal: The Journal of antibiotics 19960701

Title: Effect of acarbose on glucose homeostasis, lipogenesis and lipogenic enzyme gene expression in adipose tissue of weaned rats.

Journal: Diabetologia 19930601

Title: Altered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa).

Journal: The American journal of physiology 19911201

Title: Acarbose. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential.

Journal: Drugs 19880301

Title: Yee HS, et al. A review of the safety and efficacy of acarbose in diabetes mellitus. Pharmacotherapy. 1996;16(5):792-805.

Title: Hanefeld M, et al. Acarbose: oral anti-diabetes drug with additional cardiovascular benefits [published correction appears in Expert Rev Cardiovasc Ther. 2009 Mar;7(3):330 Expert Rev Cardiovasc Ther. 2008;6(2):153-163.

Title: Oki T, et al. Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. Biol Pharm Bull. 2000;23(9):1084-1087.

Title: Zhang Q, et al. Acarbose Reduces Blood Glucose by Activating miR-10a-5p and miR-664 in Diabetic Rats. PLoS One. 2013 Nov 18;8(11):e79697.

Title: Chan KC, et al. Pleiotropic effects of acarbose on atherosclerosis development in rabbits are mediated via upregulating AMPK signals. Sci Rep. 2016 Dec 7;6:3864

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Tags:56180-94-0 Molecular Formula|56180-94-0 MDL|56180-94-0 SMILES|56180-94-0 Acarbose