Home Amines 56287-74-2
56287-74-2,MFCD00867693
Catalog No.:AA00I9ZA

56287-74-2 | 4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-

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100mg
98%(HPLC)
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$115.00   $80.00
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500mg
98%
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$572.00   $400.00
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1g
98%(HPLC)
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I9ZA
Chemical Name:
4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
CAS Number:
56287-74-2
Molecular Formula:
C16H14FN3O
Molecular Weight:
283.3003
MDL Number:
MFCD00867693
SMILES:
FCc1nc2ccc(cc2c(=O)n1c1ccccc1C)N
Properties
Computed Properties
 
Complexity:
439  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.2  

Literature

Title: Oral muscle relaxant may induce immediate allergic reactions.

Journal: Yonsei medical journal 20120701

Title: [Survey of the current conditions in acute poisoning due to antispasmodic agents--special reference to eperisone hydrochloride and afloqualone].

Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20110901

Title: Methyl 2-[2-(benzyl-oxycarbonyl-amino)-propan-2-yl]-5-hy-droxy-6-meth-oxy-pyrimidine-4-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method.

Journal: Healthcare informatics research 20101201

Title: Exodeviated ophthalmoplegia in a patient with progressive supranuclear palsy.

Journal: Journal of Korean medical science 20091001

Title: Comparison between open procedure and tubular retractor assisted procedure for cervical radiculopathy: results of a randomized controlled study.

Journal: Journal of Korean medical science 20090801

Title: Induction of eosinophil-infiltrating drug photoallergy in mice.

Journal: Journal of dermatological science 20090701

Title: Evaluation of photoallergic potential of chemicals using THP-1 cells.

Journal: Journal of dermatological science 20081101

Title: Determination of afloqualone in human plasma using liquid chromatography/tandem mass spectrometry: Application to pharmacokinetic studies in humans.

Journal: Talanta 20071015

Title: Characterization of afloqualone N-glucuronidation: species differences and identification of human UDP-glucuronosyltransferase isoform(s).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101

Title: T Ochiai, et al. Pharmacological studies on 6-amino-2-fluoromethyl-3-(O-tolyl)-4(3H)-quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Jpn J Pharmacol. 1982 Jun;32(3):427-38.

Title: Y Kudo, et al. Effects of afloqualone on vestibular nystagmus and the lateral vestibular nucleus. Jpn J Pharmacol. 1989 Aug;50(4):515-9.

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SDS
Tags:56287-74-2 Molecular Formula|56287-74-2 MDL|56287-74-2 SMILES|56287-74-2 4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-