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5630-53-5,MFCD00864178
Catalog No.:AA00IWNL

5630-53-5 | (1S,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-2(7)-en-5-one

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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IWNL
Chemical Name:
(1S,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-2(7)-en-5-one
CAS Number:
5630-53-5
Molecular Formula:
C21H28O2
Molecular Weight:
312.4458
MDL Number:
MFCD00864178
SMILES:
C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2[C@H](C)CC2=C1CCC(=O)C2
Properties
Computed Properties
 
Complexity:
636  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.4  

Literature

Title: Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish.

Journal: Toxicology and applied pharmacology 20160815

Title: Efficacy and safety investigation of Kuntai capsule for the add-back therapy of gonadotropin releasing hormone agonist administration to endometriosis patients: a randomized, double-blind, blank- and tibolone-controlled study.

Journal: Chinese medical journal 20150220

Title: Tibolone has anti-inflammatory effects in estrogen-deficient female rats on the natriuretic peptide system and TNF-alpha.

Journal: Regulatory peptides 20121110

Title: Receptors for thyrotropin-releasing hormone, thyroid-stimulating hormone, and thyroid hormones in the macaque uterus: effects of long-term sex hormone treatment.

Journal: Menopause (New York, N.Y.) 20121101

Title: What happened to WHI: menopausal hormonal therapy in 2012.

Journal: Clinical obstetrics and gynecology 20120901

Title: A microarray study on the effect of four hormone therapy regimens on gene transcription in whole blood from healthy postmenopausal women.

Journal: Thrombosis research 20120701

Title: The risk of breast cancer linked to menopausal hormone therapy.

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20120612

Title: Safety and efficacy of tibolone and menopausal transition: a randomized, double-blind placebo-controlled trial.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20120601

Title: Treatment of premenstrual disorders by suppression of ovulation by transdermal estrogens.

Journal: Menopause international 20120601

Title: Gonadotrophin receptor hormone analogues in combination with add-back therapy: an update.

Journal: Menopause international 20120601

Title: Hormone therapy and the risk of stroke: perspectives 10 years after the Women's Health Initiative trials.

Journal: Climacteric : the journal of the International Menopause Society 20120601

Title: Does hormone therapy, tibolone or raloxifene modify VEGF expression in cervical epithelial cells?

Journal: Climacteric : the journal of the International Menopause Society 20120401

Title: Effect of chronic administration of estradiol, progesterone, and tibolone on the expression and phosphorylation of glycogen synthase kinase-3β and the microtubule-associated protein tau in the hippocampus and cerebellum of female rat.

Journal: Journal of neuroscience research 20120401

Title: Metabolism of the synthetic progestogen norethynodrel by human ketosteroid reductases of the aldo-keto reductase superfamily.

Journal: The Journal of steroid biochemistry and molecular biology 20120401

Title: Hearing levels in menopausal women and the effect of tibolone on audiological functions.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20120401

Title: Effects of long-term tibolone treatment on nuclear sex steroid hormone receptors and G-protein-coupled estrogen receptor-1 expression in the macaque uterus.

Journal: Menopause (New York, N.Y.) 20120301

Title: Vascular resistance of central retinal and ophthalmic arteries in postmenopausal women after use of tibolone.

Journal: Menopause (New York, N.Y.) 20120301

Title: Influence of estrogen deficiency and tibolone therapy on trabecular and cortical bone evaluated by computed radiography system in rats.

Journal: Acta cirurgica brasileira 20120301

Title: Short and long term effects of tibolone in postmenopausal women.

Journal: The Cochrane database of systematic reviews 20120215

Title: Raloxifene and tibolone in elderly women: a randomized, double-blind, double-dummy, placebo-controlled trial.

Journal: Journal of the American Medical Directors Association 20120201

Title: Randomized placebo- and active-controlled study of desvenlafaxine for menopausal vasomotor symptoms.

Journal: Climacteric : the journal of the International Menopause Society 20120201

Title: Chronic administration of tibolone modulates anxiety-like behavior and enhances cognitive performance in ovariectomized rats.

Journal: Hormones and behavior 20120101

Title: Acupuncture as treatment of hot flashes and the possible role of calcitonin gene-related Peptide.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Exposure to bisphosphonates and risk of cancer: a protocol for nested case-control studies using the QResearch primary care database.

Journal: BMJ open 20120101

Title: Tibolone increases bone mineral density but also relapse in breast cancer survivors: LIBERATE trial bone substudy.

Journal: Breast cancer research : BCR 20120101

Title: Sex differences in the association between serum levels of testosterone and frailty in an elderly population: the Toledo Study for Healthy Aging.

Journal: PloS one 20120101

Title: KRAS rs61764370 is associated with HER2-overexpressed and poorly-differentiated breast cancer in hormone replacement therapy users: a case control study.

Journal: BMC cancer 20120101

Title: Discontinuation of hormone replacement therapy after myocardial infarction and short term risk of adverse cardiovascular events: nationwide cohort study.

Journal: BMJ (Clinical research ed.) 20120101

Title: Incorporating bazedoxifene/conjugated estrogens into the current paradigm of menopausal therapy.

Journal: International journal of women's health 20120101

Title: Expression of Luteinizing Hormone Receptor in the Gastrointestinal Tract in Patients with and without Dysmotility.

Journal: Drug target insights 20120101

Title: Hormone replacement therapy is associated with gastro-oesophageal reflux disease: a retrospective cohort study.

Journal: BMC gastroenterology 20120101

Title: Tissue-Specific Effects of Loss of Estrogen during Menopause and Aging.

Journal: Frontiers in endocrinology 20120101

Title: Treatment options for vasomotor symptoms in menopause: focus on desvenlafaxine.

Journal: International journal of women's health 20120101

Title: 10. Cancers attributable to exposure to hormones in the UK in 2010.

Journal: British journal of cancer 20111206

Title: Historical milestones in the development of tibolone (Livial®).

Journal: Climacteric : the journal of the International Menopause Society 20111201

Title: Effect of 1-year, low-dose DHEA therapy on climacteric symptoms and female sexuality.

Journal: Climacteric : the journal of the International Menopause Society 20111201

Title: Hormone replacement therapy dependent changes in breast cancer-related gene expression in breast tissue of healthy postmenopausal women.

Journal: Molecular oncology 20111201

Title: Digitized assessment of mammographic breast density--effects of continuous combined hormone therapy, tibolone and black cohosh compared to placebo.

Journal: Maturitas 20111201

Title: Progestogens and venous thromboembolism among postmenopausal women using hormone therapy.

Journal: Maturitas 20111201

Title: Effects of tibolone on climacteric symptoms and quality of life in breast cancer patients--data from LIBERATE trial.

Journal: Maturitas 20111201

Title: Subtrochanteric fractures in bisphosphonate-naive patients: results from the HORIZON-recurrent fracture trial.

Journal: Calcified tissue international 20111201

Title: [Role of medical treatment for symptomatic leiomyoma management in premenopausal women].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20111201

Title: Prevention of osteoporosis: one step forward, two steps back.

Journal: Menopause international 20111201

Title: Visceral adiposity after tibolone use.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20111101

Title: Tibolone impairs glucose and fatty acid metabolism and induces oxidative stress in livers from female rats.

Journal: European journal of pharmacology 20111001

Title: Breast cancer medications and vision: effects of treatments for early-stage disease.

Journal: Current eye research 20111001

Title: Distribution of cyclooxygenases 1 and 2 in the uterus and breast of cynomolgus monkeys-effects of hormone treatment.

Journal: Menopause (New York, N.Y.) 20110901

Title: [Pharmacologic treatment of osteoporosis--2011].

Journal: Orvosi hetilap 20110814

Title: Hormone therapy in perimenopause and postmenopause (HT). Interdisciplinary S3 Guideline, Association of the Scientific Medical Societies in Germany AWMF 015/062-short version.

Journal: Archives of gynecology and obstetrics 20110801

Title: Effect of prolonged use of high dose of tibolone on the vagina of ovariectomized rats.

Journal: International journal of experimental pathology 20110801

Title: Menopausal hormone therapy and risk of ovarian cancer in the European prospective investigation into cancer and nutrition.

Journal: Cancer causes & control : CCC 20110801

Title: Using indirect covariance processing for structure elucidation of small molecules in cases of spectral crowding.

Journal: Magnetic resonance in chemistry : MRC 20110701

Title: The effect of weight and weight change on the long-term precision of spine and hip DXA measurements.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110501

Title: Preventive therapy for breast cancer: a consensus statement.

Journal: The Lancet. Oncology 20110501

Title: Hormone therapy administration in postmenopausal women and risk of stroke.

Journal: Women's health (London, England) 20110501

Title: Effect of tibolone on audiologic functions in menopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20110401

Title: Endometrial cancer associated with various forms of postmenopausal hormone therapy: a case control study.

Journal: International journal of cancer 20110401

Title: Effects of menopause and tibolone on different cardiovascular biomarkers in healthy women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110301

Title: Discrepancy in improvement of hearing loss between left and right ears after postmenopausal hormone therapy.

Journal: Medical hypotheses 20110301

Title: An update on hormone replacement therapy: health and medicine for women: a multidisciplinary, evidence-based review of mid-life health concerns.

Journal: The Yale journal of biology and medicine 20110301

Title: Breast cancer risk in relation to the interval between menopause and starting hormone therapy.

Journal: Journal of the National Cancer Institute 20110216

Title: Interval cancers in the NHS breast cancer screening programme in England, Wales and Northern Ireland.

Journal: British journal of cancer 20110215

Title: Low-dose tibolone (1.25 mg/d) does not affect muscle strength in older women.

Journal: Menopause (New York, N.Y.) 20110201

Title: Type of hormone therapy and risk of misclassification at mammography screening.

Journal: Menopause (New York, N.Y.) 20110201

Title: Management of menopausal symptoms in breast cancer patients.

Journal: Maturitas 20110201

Title: Sex hormones and lipoprotein(a) concentration.

Journal: Expert opinion on investigational drugs 20110201

Title: Acupuncture and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized chinese women: a randomized controlled trial.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Failure to perceive increased risk of fracture in women 55 years and older: the Global Longitudinal Study of Osteoporosis in Women (GLOW).

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110101

Title: The efficacy and tolerability of short-term low-dose estrogen-only add-back therapy during post-operative GnRH agonist treatment for endometriosis.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20110101

Title: Hormone replacement therapy and breast cancer.

Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20110101

Title: [Hormone therapy and risk for breast cancer in Finnish postmenopausal women].

Journal: Duodecim; laaketieteellinen aikakauskirja 20110101

Title: Hormone therapy for postmenopausal endometrial cancer survivors: a survey among Greek obstetricians-gynaecologists.

Journal: European journal of gynaecological oncology 20110101

Title: Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study.

Journal: BMC medical genomics 20110101

Title: Lipoprotein(a): medical treatment options for an elusive molecule.

Journal: Current pharmaceutical design 20110101

Title: Is bisphosphonate therapy for benign bone disease associated with impaired dental healing? A case-controlled study.

Journal: BMC musculoskeletal disorders 20110101

Title: Fibroids (uterine myomatosis, leiomyomas).

Journal: BMJ clinical evidence 20110101

Title: Breast pain.

Journal: BMJ clinical evidence 20110101

Title: [Comparison of two different types of hormone therapy effects on haemostatic parameters in early postmenopausal women].

Journal: Srpski arhiv za celokupno lekarstvo 20110101

Title: Role of zoledronic acid in the prevention and treatment of osteoporosis.

Journal: Clinical interventions in aging 20110101

Title: Current and emerging treatments for uterine myoma - an update.

Journal: International journal of women's health 20110101

Title: [Hormone therapy effect in postmenopausal women with history of endometrial cancer].

Journal: Ginecologia y obstetricia de Mexico 20110101

Title: Gonadotropin releasing hormone agonists: Expanding vistas.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Hormonal replacement therapy in ovarian cancer survivors: a survey among Greek gynecologists.

Journal: European journal of gynaecological oncology 20110101

Title: Synthesis of biocompatible poly(ɛ-caprolactone)- block-poly(propylene adipate) copolymers appropriate for drug nanoencapsulation in the form of core-shell nanoparticles.

Journal: International journal of nanomedicine 20110101

Title: Preventive effects of phytoestrogens against postmenopausal osteoporosis as compared to the available therapeutic choices: An overview.

Journal: Journal of natural science, biology, and medicine 20110101

Title: Facile synthesis of polyester-PEG triblock copolymers and preparation of amphiphilic nanoparticles as drug carriers.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20101220

Title: Menopausal hormone therapy and risk of endometrial carcinoma among postmenopausal women in the European Prospective Investigation Into Cancer and Nutrition.

Journal: American journal of epidemiology 20101215

Title: Low-dose hormone therapy in postmenopausal women in China.

Journal: Climacteric : the journal of the International Menopause Society 20101201

Title: Alpha-glucosidase and tyrosinase inhibitors from fungal hydroxylation of tibolone and hydroxytibolones.

Journal: Steroids 20101201

Title: Lipoprotein(a) as a cardiovascular risk factor: current status.

Journal: European heart journal 20101201

Title: Tibolone and breast cancer.

Journal: Prescrire international 20101201

Title: The effect of hormone therapy and tibolone on serum CD40L and ADAM-8 in healthy post-menopausal women.

Journal: Journal of endocrinological investigation 20101101

Title: Tibolone in postmenopausal women: a review based on recent randomised controlled clinical trials.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20101101

Title: Tibolone as a hormone replacement in women with endometriosis after bilateral oophorectomy.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20101101

Title: Wnt/Β-catenin and sex hormone signaling in endometrial homeostasis and cancer.

Journal: Oncotarget 20101101

Title: Evidence-based guidelines for the pharmacological treatment of postmenopausal osteoporosis: a consensus document by the Belgian Bone Club.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20101001

Title: The effect of fenofibrate on HDL cholesterol and HDL particle concentration in postmenopausal women on tibolone therapy.

Journal: Clinical endocrinology 20101001

Title: Effects of transdermal estradiol gel and oral tibolone on health-related quality of life after surgical menopause.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20100901

Title: Amelioration of sexual adverse effects in the early breast cancer patient.

Journal: Journal of cancer survivorship : research and practice 20100901

Title: EMAS position statement: Managing the menopause in women with a past history of endometriosis.

Journal: Maturitas 20100901

Title: Menopause perspectives and treatment of Asian women.

Journal: Seminars in reproductive medicine 20100901

Title: Practice observed.

Journal: Menopause international 20100901

Title: Updated clinical recommendations for the use of tibolone in Asian women.

Journal: Climacteric : the journal of the International Menopause Society 20100801

Title: Tamoxifen, raloxifene and tibolone decrease risk of invasive breast cancer in healthy women but increase risk of thromboembolism (tamoxifen, raloxifene), endometrial cancer (tamoxifen) or stroke (tibolone).

Journal: Evidence-based medicine 20100801

Title: [Clinical study on combination of multiple regimens in treatment of osteoporosis in perimenopause and postmenopausal women].

Journal: Zhonghua fu chan ke za zhi 20100801

Title: Transdermal and oral hormone replacement therapy and the risk of stroke: a nested case-control study.

Journal: BMJ (Clinical research ed.) 20100603

Title: Comparative effects of continuous combined hormone therapy and tibolone on body composition in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20100601

Title: Vaginal atrophy and sexual dysfunction in current users of systemic postmenopausal hormone therapy.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100601

Title: Hot flushes: are there effective alternatives to estrogen?

Journal: Menopause international 20100601

Title: Effects of 17beta-oestradiol and norethisterone acetate on sulfonation and sialylation of gonadotrophins in post-menopausal women.

Journal: Upsala journal of medical sciences 20100501

Title: Hormone replacement therapy and the risk of venous thromboembolism: a population-based study.

Journal: Journal of thrombosis and haemostasis : JTH 20100501

Title: What have we really learned from 'LIBERATE' trial?

Journal: Maturitas 20100501

Title: [Official position of the Chilean Society of Climacteric on the management of climacteric women].

Journal: Revista medica de Chile 20100501

Title: [Prevalence of use of hormone replacement therapy in women participating in a breast cancer screening program].

Journal: Medicina clinica 20100410

Title: Comparative effects of conventional hormone replacement therapy and tibolone on climacteric symptoms and sexual dysfunction in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20100401

Title: Therapeutic options for postmenopausal female sexual dysfunction.

Journal: Climacteric : the journal of the International Menopause Society 20100401

Title: Tibolone revisited: still a good treatment option for healthy, early postmenopausal women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100401

Title: ACP Journal Club. Review: Tamoxifen, raloxifene, and tibolone prevent primary invasive breast cancer but increase risk for adverse outcomes.

Journal: Annals of internal medicine 20100316

Title: Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women.

Journal: Archives of women's mental health 20100201

Title: Tibolone reduces osteoporotic fracture risk and breast cancer risk, but increases the risk of stroke.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100201

Title: Agreement of self-reported and genital measures of sexual arousal in men and women: a meta-analysis.

Journal: Archives of sexual behavior 20100201

Title: Effect of conventional and new therapies on climacteric symptoms and sexual dysfunction: a concern.

Journal: Climacteric : the journal of the International Menopause Society 20100201

Title: [Effect of high doses of tibolone in body weight and lipid profile of ovariectomized rats].

Journal: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 20100201

Title: A case-control study on hormone therapy as a risk factor for breast cancer in Finland: Intrauterine system carries a risk as well.

Journal: International journal of cancer 20100115

Title: Summary of the recommendations on sexual dysfunctions in women.

Journal: The journal of sexual medicine 20100101

Title: Reporting bias in medical research - a narrative review.

Journal: Trials 20100101

Title: Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture.

Journal: Cell communication and signaling : CCS 20100101

Title: Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis--the effect of sex, Kellgren-Lawrence (KL) score, body mass index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation.

Journal: BMC musculoskeletal disorders 20100101

Title: Probable tacrolimus toxicity from tibolone co-administration in a woman: a case report.

Journal: Journal of medical case reports 20100101

Title: Striking increases in carotid artery wall thickness in healthy subjects.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20100101

Title: Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort.

Journal: BMJ (Clinical research ed.) 20100101

Title: Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update.

Journal: Clinical interventions in aging 20100101

Title: Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions.

Journal: International journal of women's health 20100101

Title: Management of hypoactive sexual desire disorder in women: current and emerging therapies.

Journal: International journal of women's health 20100101

Title: Effect of long-time administration of tibolone on vaginal cytology of castrated rats.

Journal: Clinical and experimental obstetrics & gynecology 20100101

Title: Zoledronic acid: clinical utility and patient considerations in osteoporosis and low bone mass.

Journal: Drug design, development and therapy 20100101

Title: Editor'S comment.

Journal: Journal of mid-life health 20100101

Title: Attitudes and practices of gynecologists in Jaipur toward management of menopause.

Journal: Journal of mid-life health 20100101

Title: Non-conventional hormone therapy - Tissue-specific Tibolone-Caution.

Journal: Journal of mid-life health 20100101

Title: Endometrial adenocarcinoma in a 27-year-old woman.

Journal: Clinical medicine insights. Case reports 20100101

Title: Prevalence of cardiovascular risk factors in postmenopausal women: A rural study.

Journal: Journal of mid-life health 20100101

Title: The value of gonadotropin-releasing hormone-agonists together with other drugs for medical treatment and prevention.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20091201

Title: Systematic review: comparative effectiveness of medications to reduce risk for primary breast cancer.

Journal: Annals of internal medicine 20091117

Title: The effects of tibolone on the human primary glioblastoma multiforme cell culture and the rat C6 glioma model.

Journal: Neurological research 20091101

Title: Immediate and delayed add-back hormonal replacement therapy during ultra long GnRH agonist treatment of chronic cyclical pelvic pain.

Journal: BJOG : an international journal of obstetrics and gynaecology 20091101

Title: Validated treatments and therapeutics prospectives regarding pharmacological products for sarcopenia.

Journal: The journal of nutrition, health & aging 20091001

Title: Novel self-assembled core-shell nanoparticles based on crystalline amorphous moieties of aliphatic copolyesters for efficient controlled drug release.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20090901

Title: Repetitive surgery for recurrent symptomatic endometriosis: what to do?

Journal: European journal of obstetrics, gynecology, and reproductive biology 20090901

Title: Dissolution rate enhancement of the poorly water-soluble drug Tibolone using PVP, SiO2, and their nanocomposites as appropriate drug carriers.

Journal: Drug development and industrial pharmacy 20090901

Title: Regulation of activities of steroid hormone receptors by tibolone and its primary metabolites.

Journal: The Journal of steroid biochemistry and molecular biology 20090801

Title: Effects of different postmenopausal hormone therapy regimens on cerebral blood flow and cognitive functions.

Journal: Advances in therapy 20090801

Title: [Efficacy and safety of remifemin compared to tibolone for controlling of perimenopausal symptoms].

Journal: Zhonghua fu chan ke za zhi 20090801

Title: Patterns of hormone therapy use in the Norwegian Women and Cancer study (NOWAC) 1996-2005.

Journal: Maturitas 20090720

Title: Serum oestrogen receptor alpha and beta bioactivity are independently associated with breast cancer: a proof of principle study.

Journal: British journal of cancer 20090707

Title: Postmenopausal hormone replacement therapy modifies skeletal muscle composition and function: a study with monozygotic twin pairs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20090701

Title: Progestins induce catalase activities in breast cancer cells through PRB isoform: correlation with cell growth inhibition.

Journal: The Journal of steroid biochemistry and molecular biology 20090701

Title: The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20090701

Title: Postmenopausal hormone therapy with estradiol and norethisterone acetate and mammographic density: findings from a cross-sectional study among Norwegian women.

Journal: Climacteric : the journal of the International Menopause Society 20090601

Title: Hormonal management of migraine at menopause.

Journal: Menopause international 20090601

Title: Complex endometrial hyperplasia in the context of tibolone administration.

Journal: The Australian & New Zealand journal of obstetrics & gynaecology 20090601

Title: The LIBERATE tibolone trial in breast cancer survivors.

Journal: Maturitas 20090520

Title: Progestins in the menopause in healthy women and breast cancer patients.

Journal: Maturitas 20090420

Title: Improved bleeding profile and tolerability of tibolone versus transdermal E2/NETA treatment in postmenopausal women with female sexual dysfunction.

Journal: Climacteric : the journal of the International Menopause Society 20090401

Title: Comparison of the effects of new and conventional hormone replacement therapies on left ventricular diastolic function in healthy postmenopausal women: a Doppler and ultrasonic backscatter study.

Journal: The international journal of cardiovascular imaging 20090401

Title: Tibolone in postmenopausal women with systemic lupus erythematosus: a pilot study.

Journal: Maturitas 20090320

Title: Short-term effect of tibolone on C-reactive protein in hypertensive postmenopausal women.

Journal: Archives of gynecology and obstetrics 20090301

Title: Does tibolone reduce the risk of fracture in older postmenopausal women with osteoporosis?

Journal: Nature clinical practice. Endocrinology & metabolism 20090301

Title: The use of estrogen therapy in women's sexual functioning (CME).

Journal: The journal of sexual medicine 20090301

Title: [Effect of tibolone on endometrium of castrated rats].

Journal: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 20090301

Title: Effects of estrogen and tibolone on bladder histology and estrogen receptors in rats.

Journal: Chinese medical journal 20090220

Title: Effects of hormone therapy and tibolone on body composition and serum leptin levels in postmenopausal women.

Journal: Fertility and sterility 20090201

Title: Bleeding with menopausal hormone therapy.

Journal: Best practice & research. Clinical obstetrics & gynaecology 20090201

Title: Expression of the androgen receptor and syndecan-1 in breast tissue during different hormonal treatments in cynomolgus monkeys.

Journal: Climacteric : the journal of the International Menopause Society 20090201

Title: The impact of tibolone and hormone therapy on serum C-reactive protein, tumor necrosis factor-alpha and hepatocyte growth factor in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20090201

Title: Sexuality and the menopause.

Journal: Best practice & research. Clinical obstetrics & gynaecology 20090201

Title: Safety and efficacy of tibolone in breast-cancer patients with vasomotor symptoms: a double-blind, randomised, non-inferiority trial.

Journal: The Lancet. Oncology 20090201

Title: Tibolone: the risk is too high.

Journal: The Lancet. Oncology 20090201

Title: New findings with old drugs for osteoporosis.

Journal: Expert opinion on pharmacotherapy 20090201

Title: Use of hormone replacement therapy, 1998-2007: sustained impact of the Women's Health Initiative findings.

Journal: The Annals of pharmacotherapy 20090201

Title: Estrogen sulfotransferases in breast and endometrial cancers.

Journal: Annals of the New York Academy of Sciences 20090201

Title: Hormone therapy for endometriosis and surgical menopause.

Journal: The Cochrane database of systematic reviews 20090121

Title: Tibolone low dose (1.25 mg/d) therapy and postural balance in elderly women.

Journal: Maturitas 20090120

Title: [Osteoporosis].

Journal: Revue medicale suisse 20090114

Title: Effects of hormone replacement therapy on insulin resistance and platelet function tests.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20090101

Title: Hormone therapy and risk of myocardial infarction.

Journal: Women's health (London, England) 20090101

Title: Breast cancer in young women and its impact on reproductive function.

Journal: Human reproduction update 20090101

Title: The estrogenic component of tibolone reduces adiposity in female aromatase knockout mice.

Journal: Menopause (New York, N.Y.) 20090101

Title: Ultrasound protocols to measure carotid intima-media thickness: a post-hoc analysis of the OPAL study.

Journal: Current medical research and opinion 20090101

Title: Hormone therapy for postmenopausal breast cancer survivors: a survey among obstetrician-gynaecologists.

Journal: European journal of gynaecological oncology 20090101

Title: Inflammatory markers in a 2-year soy intervention among premenopausal women.

Journal: Journal of inflammation (London, England) 20090101

Title: Effects of either tibolone or continuous combined transdermal estradiol with medroxyprogesterone acetate on coagulatory factors and lipoprotein(a) in menopause.

Journal: Gynecologic and obstetric investigation 20090101

Title: [Changes in the use of hormone replacement therapy after an educational intervention aimed at women and prescribers].

Journal: Gaceta sanitaria 20090101

Title: Once-yearly zoledronic acid in hip fracture prevention.

Journal: Clinical interventions in aging 20090101

Title: Treatment of osteoporosis with annual iv zoledronic acid: effects on hip fracture.

Journal: Therapeutics and clinical risk management 20090101

Title: Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis.

Journal: PloS one 20090101

Title: Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women.

Journal: Breast cancer research : BCR 20090101

Title: Interactions between herbal medicines and prescribed drugs: an updated systematic review.

Journal: Drugs 20090101

Title: Chinese medicinal herbs in relieving perimenopausal depression: a randomized, controlled trial.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20090101

Title: [Modern tendencies in HRT of patients treated for endometrial cancer].

Journal: Akusherstvo i ginekologiia 20090101

Title: Intravenous zoledronic acid for the treatment of osteoporosis: The evidence of its therapeutic effect.

Journal: Core evidence 20090101

Title: Tibolone vaginal versus per os administration in the management of post-menopausal symptoms.

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20090101

Title: Effects of tibolone and conventional HRT on the expression of estrogen and progesterone receptors in the breast.

Journal: Maturitas 20081220

Title: Hormone replacement therapy use and the risk of stroke.

Journal: Maturitas 20081220

Title: Bioequivalence studies of tibolone in premenopausal women and effects on expression of the tibolone-metabolizing enzyme AKR1C (aldo-keto reductase) family caused by estradiol.

Journal: Journal of clinical pharmacology 20081201

Title: Tibolone rapidly attenuates the GABAB response in hypothalamic neurones.

Journal: Journal of neuroendocrinology 20081201

Title: Tibolone reduced risk for fractures and breast cancer but increased risk for stroke in older women with osteoporosis.

Journal: ACP journal club 20081118

Title: Tibolone in older postmenopausal women.

Journal: The New England journal of medicine 20081113

Title: Tibolone in older postmenopausal women.

Journal: The New England journal of medicine 20081113

Title: Hormone therapy and risk of myocardial infarction: a national register study.

Journal: European heart journal 20081101

Title: [The influence of a tibolone therapy on endometrium in postmenopausal women].

Journal: Ginekologia polska 20081101

Title: [Tibolone's effect on retinal and ophthalmic arteries flowmetry].

Journal: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 20081101

Title: Estradiol valerate and tibolone: effects upon brain oxidative stress and blood biochemistry during aging in female rats.

Journal: Biogerontology 20081001

Title: Impact of soy supplementation on sex steroids and vascular inflammation markers in postmenopausal women using tibolone: role of equol production capability.

Journal: Climacteric : the journal of the International Menopause Society 20081001

Title: Anti-resorptives in the management of osteoporosis.

Journal: Best practice & research. Clinical endocrinology & metabolism 20081001

Title: [Relation between hormonal therapy and tibolone with SERMs in postmenopausal women's myomes growth].

Journal: Ginecologia y obstetricia de Mexico 20081001

Title: Association of ovarian and uterine cancers with postmenopausal hormonal treatments.

Journal: Clinical obstetrics and gynecology 20080901

Title: Endometrial effects of tibolone in elderly, osteoporotic women.

Journal: Obstetrics and gynecology 20080901

Title: [Hormones and mammographic breast density].

Journal: Journal de radiologie 20080901

Title: The effects of tibolone in older postmenopausal women.

Journal: The New England journal of medicine 20080814

Title: Tibolone and the promise of ideal hormone-replacement therapy.

Journal: The New England journal of medicine 20080814

Title: Effects of tibolone and raloxifene on bone mineral density in osteopenic postmenopausal women.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080801

Title: Effects of fulvestrant alone or combined with different steroids in human breast cancer cells in vitro.

Journal: Climacteric : the journal of the International Menopause Society 20080801

Title: Tibolone reverses the cognitive effects caused by leuprolide acetate administration, improving mood and quality of life in patients with symptomatic uterine leiomyomas.

Journal: Fertility and sterility 20080701

Title: Differential impact of conventional-dose and low-dose postmenopausal hormone therapy, tibolone and raloxifene on C-reactive protein and other inflammatory markers.

Journal: Journal of thrombosis and haemostasis : JTH 20080601

Title: Tibolone and breast cancer risk: effects of selection bias cannot be eliminated in observational studies.

Journal: BJOG : an international journal of obstetrics and gynaecology 20080601

Title: Effects of estrogen and estrogenic compounds on cognition in ovariectomized rats.

Journal: Climacteric : the journal of the International Menopause Society 20080601

Title: The influence of estradiole and tibolone administration on leptin levels in women with surgically induced menopause.

Journal: Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20080601

Title: The menopausal hot flush--anything new?

Journal: Maturitas 20080520

Title: Equol production capability is associated with favorable vascular function in postmenopausal women using tibolone; no effect with soy supplementation.

Journal: Atherosclerosis 20080501

Title: Hormone therapy alters the composition of the vaginal microflora in ovariectomized rats.

Journal: Microbial ecology 20080501

Title: Differential impact of conventional and low-dose oral hormone therapy, tibolone and raloxifene on mammographic breast density, assessed by an automated quantitative method.

Journal: BJOG : an international journal of obstetrics and gynaecology 20080501

Title: Differential effect of hormone therapy on E1S-sulfatase activity in non-malignant and cancerous breast cells in vitro.

Journal: Breast cancer research and treatment 20080401

Title: E-cadherin expression in cervical epithelial cells of postmenopausal women: association with hormone therapy, tibolone, and raloxifene.

Journal: Fertility and sterility 20080401

Title: Loss of treatment benefit due to low compliance with bisphosphonate therapy.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080401

Title: An evidence-based approach to hormonal therapies for premenopausal women with fibroids.

Journal: Best practice & research. Clinical obstetrics & gynaecology 20080401

Title: Brachial artery responses in menopausal women using tibolone.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080401

Title: Circulating levels of atherogenesis-associated adipocytokines and apoptotic markers are differentially influenced by hormone therapy, tibolone and raloxifene in healthy postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20080401

Title: Tibolone is not aromatized in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20080401

Title: Tibolone: the way to beat many a postmenopausal ailments.

Journal: Expert opinion on pharmacotherapy 20080401

Title: The short-term effect of increased body weight in menopausal Chinese women taking tibolone.

Journal: Maturitas 20080320

Title: Tibolone and transdermal E2/NETA for the treatment of female sexual dysfunction in naturally menopausal women: results of a randomized active-controlled trial.

Journal: The journal of sexual medicine 20080301

Title: Care of women in menopause: sexual function, dysfunction and therapeutic modalities.

Journal: Annals of the Academy of Medicine, Singapore 20080301

Title: Role of androgens, progestins and tibolone in the treatment of menopausal symptoms: a review of the clinical evidence.

Journal: Clinical interventions in aging 20080301

Title: HT update: spotlight on estradiol/norethindrone acetate combination therapy.

Journal: Clinical interventions in aging 20080301

Title: Efficacy of tibolone as 'add-back therapy' in conjunction with a gonadotropin-releasing hormone analogue in the treatment of uterine fibroids.

Journal: Fertility and sterility 20080201

Title: Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina.

Journal: Human reproduction (Oxford, England) 20080201

Title: The effect of different preparations of hormone therapy on tumor necrosis factor-alpha levels in women with surgical menopause.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080201

Title: Circulating leptin and ghrelin are differentially influenced by estrogen/progestin therapy and raloxifene.

Journal: Maturitas 20080120

Title: Still waiting and searching for answers.

Journal: BMJ (Clinical research ed.) 20080105

Title: Effects of intravenous zoledronic acid once yearly on bone remodeling and bone structure.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080101

Title: Comparison of the effects of hormone therapy regimens, oral and vaginal estradiol, estradiol + drospirenone and tibolone, on sexual function in healthy postmenopausal women.

Journal: The journal of sexual medicine 20080101

Title: Enantioselective production of 3-hydroxy metabolites of tibolone by yeast reduction.

Journal: Steroids 20080101

Title: 3beta-OH-tibolone acutely dilates rat muscle arterioles similar to 3alpha-OH-tibolone.

Journal: Menopause (New York, N.Y.) 20080101

Title: Hormone replacement therapy use and variations in the risk of breast cancer.

Journal: BJOG : an international journal of obstetrics and gynaecology 20080101

Title: Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer postgenome cohort - a cross-sectional analysis.

Journal: BMC women's health 20080101

Title: Effects of tibolone metabolites on human endometrial cell lines in co-culture.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20080101

Title: Pharmacological therapy for female sexual dysfunction: has progress been made?

Journal: Drugs 20080101

Title: Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. John's wort). Case of drug interaction?

Journal: Acta gastro-enterologica Belgica 20080101

Title: A randomized double-blind placebo-controlled trial to investigate the effects of nasal calcitonin on bone microarchitecture measured by high-resolution peripheral quantitative computerized tomography in postmenopausal women - study protocol.

Journal: Trials 20080101

Title: Anti-tumor-Promoting activity of tibolone and its metabolites.

Journal: Arzneimittel-Forschung 20080101

Title: Non-pharmaceutical prevention of hip fractures - a cost-effectiveness analysis of a community-based elderly safety promotion program in Sweden.

Journal: Cost effectiveness and resource allocation : C/E 20080101

Title: Efficacy of tibolone and raloxifene for the maintenance of skeletal muscle strength, bone mineral density, balance, body composition, cognitive function, mood/depression, anxiety and quality of life/well-being in late postmenopausal women >/= 70 years: study design of a randomized, double-blind, double-dummy, placebo-controlled, single-center trial.

Journal: Trials 20080101

Title: Gallbladder disease and use of transdermal versus oral hormone replacement therapy in postmenopausal women: prospective cohort study.

Journal: BMJ (Clinical research ed.) 20080101

Title: Epigenotyping in peripheral blood cell DNA and breast cancer risk: a proof of principle study.

Journal: PloS one 20080101

Title: Soy-tibolone combination - effect on lipids in postmenopausal monkeys and women.

Journal: Maturitas 20080101

Title: The growth-promoting action of individual women's sera on mammary carcinoma cells.

Journal: Anticancer research 20080101

Title: A comparison of hormone therapies on the urinary excretion of prostacyclin and thromboxane A2.

Journal: Climacteric : the journal of the International Menopause Society 20080101

Title: The effect of continuous combined conjugated equine estrogen plus medroxyprogesterone acetate and tibolone on cardiovascular metabolic risk factors.

Journal: Climacteric : the journal of the International Menopause Society 20080101

Title: Tibolone inhibits bone resorption without secondary positive effects on cartilage degradation.

Journal: BMC musculoskeletal disorders 20080101

Title: Risk factors for osteoporosis and fractures in postmenopausal women between 50 and 65 years of age in a primary care setting in Spain: a questionnaire.

Journal: The open rheumatology journal 20080101

Title: The effect of transdermal estradiol or oral conjugated oestrogen and fenretinide versus placebo on haemostasis and cardiovascular risk biomarkers in a randomized breast cancer chemoprevention trial.

Journal: Ecancermedicalscience 20080101

Title: Tibolone and osteoporosis.

Journal: Archives of gynecology and obstetrics 20071201

Title: Safety of tibolone in the treatment of vasomotor symptoms in breast cancer patients--design and baseline data 'LIBERATE' trial.

Journal: Breast (Edinburgh, Scotland) 20071201

Title: Tibolone and low-dose continuous combined hormone treatment: vaginal bleeding pattern, efficacy and tolerability.

Journal: BJOG : an international journal of obstetrics and gynaecology 20071201

Title: Agonist activity of the 3-hydroxy metabolites of tibolone through the oestrogen receptor in the mouse N20.1 oligodendrocyte cell line and normal human astrocytes.

Journal: Journal of neuroendocrinology 20071201

Title: Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation.

Journal: Climacteric : the journal of the International Menopause Society 20071201

Title: Ultrastructure study of postmenopausal endometria of tibolone, conjugated estrogen + medroxyprogesterone acetate and tamoxifen users.

Journal: Saudi medical journal 20071201

Title: The effects of raloxifene and tibolone on homocysteine and vascular histopathological changes.

Journal: Clinical and experimental medicine 20071201

Title: Effect of different hormonal therapies on thyroid function in surgical menopause: short-term results.

Journal: The Journal of reproductive medicine 20071201

Title: 3-ketosteroid reductase activity and expression by fetal rat osteoblasts.

Journal: The Journal of biological chemistry 20071123

Title: Economic impact of Tibolone compared with Continuous-Combined Hormone Replacement Therapy in the management of climacteric symptoms in postmenopausal women.

Journal: Maturitas 20071020

Title: Effects of tibolone and raloxifene on health-related quality of life and sexual function.

Journal: Maturitas 20071020

Title: Tibolone histology of the endometrium and breast endpoints study: design of the trial and endometrial histology at baseline in postmenopausal women.

Journal: Fertility and sterility 20071001

Title: Effects of tibolone on health-related quality of life in menopausal women.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20071001

Title: The differential effect of estrogen, estrogen-progestin and tibolone on coagulation inhibitors in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20071001

Title: Menopause and stroke and the effects of hormonal therapy.

Journal: Climacteric : the journal of the International Menopause Society 20071001

Title: Effects of hormone treatment on hemostasis variables.

Journal: Climacteric : the journal of the International Menopause Society 20071001

Title: Endometrial safety and bleeding with HRT: what's new?

Journal: Climacteric : the journal of the International Menopause Society 20071001

Title: Progestins and breast cancer.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20071001

Title: In vitro effects of tibolone and its metabolites on human vascular coronary cells.

Journal: Maturitas 20070920

Title: Postmenopausal HRT and tibolone in relation to muscle strength and body composition.

Journal: Maturitas 20070920

Title: Efficacy and tolerability of a medicinal product containing an isopropanolic black cohosh extract in Chinese women with menopausal symptoms: a randomized, double blind, parallel-controlled study versus tibolone.

Journal: Maturitas 20070920

Title: Prescribing of hormone therapy for menopause, tibolone, and bisphosphonates in women in the UK between 1991 and 2005.

Journal: European journal of clinical pharmacology 20070901

Title: Effects of tibolone and its metabolites on Angiopoietin-1, Tie-2 and tumor necrosis factor-alpha mRNA in Ishikawa cells. Implication for tibolone's effects on the endometrium.

Journal: Maturitas 20070820

Title: Can 19-nortestosterone derivatives be aromatized in the liver of adult humans? Are there clinical implications?

Journal: Climacteric : the journal of the International Menopause Society 20070801

Title: [Review of pharmacological treatment of the menopause].

Journal: Atencion primaria 20070801

Title: Effect of tibolone on breast cancer cell proliferation in postmenopausal ER+ patients: results from STEM trial.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070715

Title: The incidence and characteristics of uterine bleeding during postoperative GnRH agonist treatment combined with tibolone add-back therapy in endometriosis patients of reproductive age.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20070701

Title: Circulating chemoattractants RANTES, negatively related to endogenous androgens, and MCP-1 are differentially suppressed by hormone therapy and raloxifene.

Journal: Atherosclerosis 20070701

Title: Pharmacokinetic parameters of tibolone and metabolites in plasma, urine, feces, and bile from ovariectomized cynomolgus monkeys after a single dose or multiple doses of tibolone.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Selective tissue distribution of tibolone metabolites in mature ovariectomized female cynomolgus monkeys after multiple doses of tibolone.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20070701

Title: Hormone therapy and raloxifene reduce the coagulation inhibitor potential.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070701

Title: Drug-induced acute cholestatic liver damage in a patient with mutation of UGT1A1.

Journal: Nature clinical practice. Gastroenterology & hepatology 20070701

Title: [The level of pregnancy-associated alpha2-glycoprotein and the hormonal background during different options of hormonal replacement therapy in the menopausal syndrome].

Journal: Klinicheskaia laboratornaia diagnostika 20070701

Title: Systemic lupus erythematosus and hormone replacement therapy.

Journal: Menopause international 20070601

Title: Differential impact of conventional and low-dose oral hormone therapy (HT), tibolone and raloxifene on functionality of the activated protein C system.

Journal: Thrombosis and haemostasis 20070601

Title: [Aging and sexuality in women].

Journal: Minerva ginecologica 20070601

Title: Effects of tibolone on the breast of postmenopausal women.

Journal: Taiwanese journal of obstetrics & gynecology 20070601

Title: Tibolone for prevention and treatment of postmenopausal osteoporosis.

Journal: Maturitas 20070520

Title: Molecular analysis of human endometrium: short-term tibolone signaling differs significantly from estrogen and estrogen + progestagen signaling.

Journal: Journal of molecular medicine (Berlin, Germany) 20070501

Title: Tibolone and its delta-4, 7alpha-methyl norethisterone metabolite are reversible inhibitors of human aromatase.

Journal: The Journal of steroid biochemistry and molecular biology 20070501

Title: Traditional nonsteroidal anti-inflammatory drugs and postmenopausal hormone therapy: a drug-drug interaction?

Journal: PLoS medicine 20070501

Title: A case report of recurrent endometriosis following Tibolone hormone replacement therapy.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20070501

Title: Long-term effects of tibolone on ocular functions in postmenopausal women.

Journal: Archives of gynecology and obstetrics 20070401

Title: A comparative study of the effect of continuous combined conjugated equine estrogen plus medroxyprogesterone acetate and tibolone on blood coagulability.

Journal: Human reproduction (Oxford, England) 20070401

Title: Comparison of the effects of tibolone and estrogen therapy on hemostasis in surgical menopause: a randomized, double-blind, placebo-controlled study.

Journal: Fertility and sterility 20070401

Title: Pharmacokinetic parameters of sulfated tibolone metabolites in postmenopausal women after single and multiple doses of tibolone.

Journal: Clinical pharmacology and therapeutics 20070401

Title: Tibolone: example of qualitative and quantitative assessments of the mammary gland.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20070401

Title: Ultrasound appearance of the uterus in women over 60 years of age on tibolone: is it a SERM?

Journal: Climacteric : the journal of the International Menopause Society 20070401

Title: Effectiveness of tibolone on the reduction of menopausal problems--a Bayesian semi-parametric interpretation.

Journal: Statistics in medicine 20070315

Title: Use of gonadotropin-releasing hormone agonists in patients with Hodgkin's disease for preservation of ovarian function and reduction of gonadotoxicity related to chemotherapy.

Journal: Fertility and sterility 20070301

Title: Endometrial effects of tibolone.

Journal: The Journal of clinical endocrinology and metabolism 20070301

Title: [Comparison of different antidepression therapy in perimenopausal and postmenopausal women with depression].

Journal: Zhonghua fu chan ke za zhi 20070301

Title: The attitude of gynecologists in São Paulo, Brazil 3 years after the Women's Health Initiative study.

Journal: Maturitas 20070220

Title: Tibolone therapy in breast cancer survivors: a retrospective study.

Journal: The journal of obstetrics and gynaecology research 20070201

Title: Treatment of hereditary angioneurotic oedema (HANE) with tibolone.

Journal: Clinical endocrinology 20070201

Title: Safety of alternative treatments for menopausal symptoms after breast cancer: a qualitative systematic review.

Journal: Climacteric : the journal of the International Menopause Society 20070201

Title: Estrogen and tibolone metabolite levels in blood and breast tissue of postmenopausal women recently diagnosed with early-stage breast cancer and treated with tibolone or placebo for 14 days.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20070201

Title: Levels of tibolone and estradiol and their nonsulfated and sulfated metabolites in serum, myometrium, and vagina of postmenopausal women following treatment for 21 days with tibolone, estradiol, or estradiol plus medroxyprogestrone acetate.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20070201

Title: The effect of tibolone versus 17beta-estradiol on climacteric symptoms in women with surgical menopause: a randomized, cross-over study.

Journal: Maturitas 20070120

Title: Tibolone (Livial) enhances warfarin-induced anticoagulation in postmenopausal women.

Journal: Maturitas 20070120

Title: [Osteoporosis treatment].

Journal: Revue medicale suisse 20070117

Title: Conjugated estrogens and tibolone modify the gonadotrophin glycosylation pattern in postmenopausal women.

Journal: Gynecologic and obstetric investigation 20070101

Title: Effects of tibolone on sulfatase pathway of estrogens metabolism and on growth of MCF-7 human breast tumors implanted in ovariectomized nude mice.

Journal: Gynecologic and obstetric investigation 20070101

Title: Differential effects of conventional and low dose oral hormone therapy (HT), tibolone, and raloxifene on coagulation and fibrinolysis.

Journal: Thrombosis research 20070101

Title: Preferential prescribing of tibolone and combined estrogen plus progestogen therapy in postmenopausal women.

Journal: Menopause (New York, N.Y.) 20070101

Title: Body Mass Index, percent body fat, and regional body fat distribution in relation to leptin concentrations in healthy, non-smoking postmenopausal women in a feeding study.

Journal: Nutrition journal 20070101

Title: 7alpha-Methyl-ethinyl estradiol is not a metabolite of tibolone but a chemical stress artifact.

Journal: Menopause (New York, N.Y.) 20070101

Title: Postmenopausal tibolone therapy: biologic principles and applied clinical practice.

Journal: MedGenMed : Medscape general medicine 20070101

Title: Colon cancer risk and different HRT formulations: a case-control study.

Journal: BMC cancer 20070101

Title: In vivo conversion of TIB to MEE not an artifact generated by heat.

Journal: Menopause (New York, N.Y.) 20070101

Title: Cardiovascular effects of tibolone: a selective tissue estrogenic activity regulator.

Journal: Cardiovascular drug reviews 20070101

Title: Breast cancer metastasis to the stomach may mimic primary gastric cancer: report of two cases and review of literature.

Journal: World journal of surgical oncology 20070101

Title: Interactions of the human cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene.

Journal: The Journal of steroid biochemistry and molecular biology 20070101

Title: Carotid intima-medial thickness measured on multiple ultrasound frames: evaluation of a DICOM-based software system.

Journal: Cardiovascular ultrasound 20070101

Title: Correlation of estrogen sulfotransferase activity and proliferation in normal and carcinomatous human breast. A hypothesis.

Journal: Anticancer research 20070101

Title: Effect of tibolone on sexual function in late postmenopausal women.

Journal: Folia medica 20070101

Title: Mammographic density--a risk factor for breast cancer.

Journal: Prague medical report 20070101

Title: Breast pain.

Journal: BMJ clinical evidence 20070101

Title: Fibroids (uterine myomatosis, leiomyomas).

Journal: BMJ clinical evidence 20070101

Title: New insights into the understanding of gastrointestinal dysmotility.

Journal: Drug target insights 20070101

Title: Is HRT justified for symptom management in women at higher risk of developing breast cancer?

Journal: Climacteric : the journal of the International Menopause Society 20061201

Title: Effect of different preparations of hormone therapy on sexual dysfunction in naturally postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20061201

Title: Metabolism of exogenous sex steroids and effect on brain functions with a focus on tibolone.

Journal: The Journal of steroid biochemistry and molecular biology 20061201

Title: Semiparametric analysis of two-level bivariate binary data.

Journal: Biometrics 20061201

Title: Quality of life and psychological symptoms in Greek postmenopausal women: association with hormone therapy.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20061201

Title: Estradiol valerate and tibolone: effects on memory.

Journal: Pharmacology, biochemistry, and behavior 20061201

Title: The hormone replacement therapy drug tibolone acts very similar to medroxyprogesterone acetate in an estrogen-and progesterone-responsive endometrial cancer cell line.

Journal: Journal of molecular endocrinology 20061201

Title: Sexuality and the menopause.

Journal: The journal of the British Menopause Society 20061201

Title: Effects of tibolone and continuous combined conjugated equine estrogen/medroxyprogesterone acetate on the endometrium and vaginal bleeding: results of the OPAL study.

Journal: American journal of obstetrics and gynecology 20061101

Title: Assessment of mammographic density changes on plain film mammograms in postmenopausal women on hormone replacement therapy.

Journal: The Indian journal of medical research 20061101

Title: Endometrial cancer patients and tibolone: a matched case-control study.

Journal: Maturitas 20061020

Title: Conventional-dose hormone therapy (HT) and tibolone, but not low-dose HT and raloxifene, increase markers of activated coagulation.

Journal: Maturitas 20061020

Title: Clitoral circulation in postmenopausal women with sexual dysfunction: a pilot randomized study with hormone therapy.

Journal: Maturitas 20061020

Title: Regulation of SULT1E1 expression in Ishikawa adenocarcinoma cells by tibolone.

Journal: Steroids 20061001

Title: Long-term effects of tibolone on circulating levels of vascular cell adhesion molecules and E-selectin in postmenopausal women.

Journal: Fertility and sterility 20061001

Title: Hormone replacement therapy in women with past history of endometriosis.

Journal: Climacteric : the journal of the International Menopause Society 20061001

Title: Tibolone and breast cancer.

Journal: Postgraduate medical journal 20061001

Title: The safety of tibolone in epithelial ovarian cancer patients.

Journal: Maturitas 20060920

Title: Effects of stable transfection of human fetal osteoblast cells with estrogen receptor-alpha on regulation of gene expression by tibolone.

Journal: Bone 20060901

Title: Tibolone exerts progestational inhibition of matrix metalloproteinase expression in human endometrial stromal cells.

Journal: Steroids 20060901

Title: Effects of long-term hormone treatment and of tibolone on monoamines and monoamine metabolites in the brains of ovariectomised, Cynomologous monkeys.

Journal: Journal of neuroendocrinology 20060901

Title: Progestagenic effects of tibolone are target gene-specific in human endometrial cells.

Journal: Journal of the Society for Gynecologic Investigation 20060901

Title: Metabolism of tibolone and its metabolites in uterine and vaginal tissue of rat and human origin.

Journal: The Journal of steroid biochemistry and molecular biology 20060901

Title: The effects of different hormone replacement therapy regimens on tear function, intraocular pressure and lens opacity.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060901

Title: Management of age-related osteoporosis and prevention of associated fractures.

Journal: Therapeutics and clinical risk management 20060901

Title: Beneficial effect of tibolone on mood, cognition, well-being, and sexuality in menopausal women.

Journal: Neuropsychiatric disease and treatment 20060901

Title: Improved detectability in pharmacokinetic study of tibolone by gas chromatography-high resolution mass spectrometry with selected ion monitoring.

Journal: Talanta 20060815

Title: Assessment of DNA damage in postmenopausal women under osteoporosis therapy.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20060801

Title: Strength of cancellous bone trabecular tissue from normal, ovariectomized and drug-treated rats over the course of ageing.

Journal: Bone 20060801

Title: Effects of hormone replacement therapy type and route of administration on plasma matrix metalloproteinases and their tissue inhibitors in postmenopausal women.

Journal: The Journal of clinical endocrinology and metabolism 20060801

Title: Tibolone and metabolites induce prolactin production in human endometrial stromal cells in vitro: evidence for cell-specific metabolism.

Journal: The Journal of steroid biochemistry and molecular biology 20060801

Title: Tibolone and estradiol plus norethisterone acetate similarly influence endothelium-dependent vasodilatation in healthy postmenopausal women.

Journal: Fertility and sterility 20060801

Title: Histological and immunohistochemical evaluation of postmenopausal endometrium after 3 weeks of treatment with tibolone, estrogen only, or estrogen plus progestagen.

Journal: Fertility and sterility 20060801

Title: Tibolone in the treatment of menopause: compliance, efficacy and safety in a ten year experience.

Journal: Minerva ginecologica 20060801

Title: Loss of libido in postmenopausal women.

Journal: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20060801

Title: Sexual dysfunction in the peri- and postmenopause. Status of incidence, pharmacological treatment and possible risks. A secondary publication.

Journal: Danish medical bulletin 20060801

Title: Lack of aromatisation of the 3-keto-4-ene metabolite of tibolone to an estrogenic derivative.

Journal: Steroids 20060701

Title: Estrogenic effects of natural and synthetic compounds including tibolone assessed in Saccharomyces cerevisiae expressing the human estrogen alpha and beta receptors.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701

Title: Effects of tibolone on nuclear receptors in human endometrial cells.

Journal: American journal of obstetrics and gynecology 20060701

Title: [Effects of alendronate on bone mineral density, cytokines and indices of bone metabolism in postmenopausal osteoporotic patients].

Journal: Zhonghua nei ke za zhi 20060701

Title: Tibolone and its metabolites inhibit invasion of human mammary carcinoma cells in vitro.

Journal: Maturitas 20060620

Title: Tibolone: cancers of the breast and endometrium.

Journal: Prescrire international 20060601

Title: Tibolone and stroke.

Journal: Prescrire international 20060601

Title: Tibolone is not used as a first-line therapy: implications for the Million Women Study analysis.

Journal: The journal of the British Menopause Society 20060601

Title: Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs).

Journal: Steroids 20060501

Title: Molecular docking simulations of steroid substrates into human cytosolic hydroxysteroid dehydrogenases (AKR1C1 and AKR1C2): insights into positional and stereochemical preferences.

Journal: Steroids 20060501

Title: Effect of misoprostol on bone mineral density in women with postmenopausal osteoporosis.

Journal: Prostaglandins & other lipid mediators 20060501

Title: Preoperative treatment of uterine leiomyomas: clinical findings and expression of transforming growth factor-beta3 and connective tissue growth factor.

Journal: Journal of the Society for Gynecologic Investigation 20060501

Title: [Comparative study of effects of hormonal therapies on the healing of fracture in ovariectomized rats and Rats' endometria].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060501

Title: Short-term effects of hormone therapy on serum C-reactive protein levels in postmenopausal women.

Journal: Archives of gynecology and obstetrics 20060401

Title: Controversies regarding hormone therapy: Insights from inflammation and hemostasis.

Journal: Cardiovascular research 20060401

Title: Effects of menopause and postmenopausal tibolone treatment on plasma TNFalpha, IL-4, IL-10, IL-12 cytokine pattern and some bone turnover markers.

Journal: Pharmacological research 20060401

Title: Clinical evaluation of women presenting with low libido and determination of whether androgen therapy might be appropriate.

Journal: Seminars in reproductive medicine 20060401

Title: Hormone therapy in the WHI era.

Journal: The Australian & New Zealand journal of obstetrics & gynaecology 20060401

Title: Differential effect of hormone therapy and tibolone on lipids, lipoproteins, and the atherogenic index of plasma.

Journal: Journal of cardiovascular pharmacology 20060401

Title: [Effects of tibolone on the risk factors for cardiovascular diseases in postmenopausal women].

Journal: Vojnosanitetski pregled 20060401

Title: Homocysteine, estrogen and cognitive decline.

Journal: Climacteric : the journal of the International Menopause Society 20060401

Title: [Profiles of irregular bleeding induced by low-dose hormone therapy and Chinese formulated herbs products].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20060401

Title: Inflammatory activity and anticardiolipin antibodies during tibolone treatment of healthy postmenopausal women.

Journal: Methods and findings in experimental and clinical pharmacology 20060401

Title: A 5-year study on the effect of hormone therapy, tibolone and raloxifene on vaginal bleeding and endometrial thickness.

Journal: Maturitas 20060320

Title: LIFT study is discontinued.

Journal: BMJ (Clinical research ed.) 20060318

Title: Tibolone metabolism in human liver is catalyzed by 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four isoforms of the aldo-keto reductase (AKR)1C subfamily.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

Title: Does tibolone exacerbate atherosclerosis?

Journal: European heart journal 20060301

Title: The effect of tibolone and continuous combined conjugated equine oestrogens plus medroxyprogesterone acetate on progression of carotid intima-media thickness: the Osteoporosis Prevention and Arterial effects of tiboLone (OPAL) study.

Journal: European heart journal 20060301

Title: [Is the clinical profile of women treated with tibolone similar to that of women receiving a classical estrogen-progestogen therapy? Data from a nationwide survey in France].

Journal: Gynecologie, obstetrique & fertilite 20060301

Title: Biochemical markers surrogating on vascular effects of sex steroid hormones.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060301

Title: Vaginal polyps and hormones--is there a link? A case series.

Journal: Maturitas 20060220

Title: Myocardial infarction risk and hormone replacement: differences between products.

Journal: Maturitas 20060220

Title: The effect of raloxifene and tibolone on the uterine blood flow and endometrial thickness: a transvaginal Doppler study.

Journal: Maturitas 20060220

Title: [Up-to-date treatments for osteoporosis].

Journal: Orvosi hetilap 20060219

Title: Tibolone improves myocardial perfusion in postmenopausal women with ischemic heart disease: an open-label exploratory pilot study.

Journal: Journal of the American College of Cardiology 20060207

Title: [Sexual dysfunction in the menopause. Incidence, pharmacological treatment and side effects].

Journal: Ugeskrift for laeger 20060206

Title: The thoughts of physicians regarding the need to start hormone replacement therapy in breast cancer survivors.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20060201

Title: Effects of tibolone on blood flow resistance and intima-media thickness of the carotid arteries: effect of time since menopause.

Journal: Climacteric : the journal of the International Menopause Society 20060201

Title: Effects of tibolone on selectins in postmenopausal women.

Journal: Maturitas 20060120

Title: Hormone replacement therapy and risks of oesophageal and gastric adenocarcinomas.

Journal: British journal of cancer 20060116

Title: Postmenopausal hormone therapy and mammographic breast density.

Journal: Maturitas 20060110

Title: Evaluation of mammographic density and (99m)Tc-sestamibi scintimammographic uptake in postmenopausal women on hormone replacement therapy.

Journal: Maturitas 20060110

Title: Conjugated estrogen/progestagen versus tibolone hormone replacement therapy in postmenopausal women: Effects on carbohydrate metabolism and serum sex hormone-binding globulin.

Journal: Maturitas 20060110

Title: Hormone replacement therapy and false positive recall in the Million Women Study: patterns of use, hormonal constituents and consistency of effect.

Journal: Breast cancer research : BCR 20060101

Title: Effect of tibolone administration on central and peripheral levels of allopregnanolone and beta-endorphin in female rats.

Journal: Menopause (New York, N.Y.) 20060101

Title: Attitudes of Korean clinicians to postmenopausal hormone therapy after the Women's Health Initiative study.

Journal: Menopause (New York, N.Y.) 20060101

Title: Effects of tibolone on estrogen biosynthesis in the mammary tissue of postmenopausal monkeys.

Journal: Menopause (New York, N.Y.) 20060101

Title: Effects of hormone replacement therapy and tibolone on skin thickness and bone in postmenopausal women.

Journal: Annals of Saudi medicine 20060101

Title: Serum leptin levels and body composition in postmenopausal women treated with tibolone and raloxifene.

Journal: Menopause (New York, N.Y.) 20060101

Title: Different effects of tibolone and low-dose EPT in the management of postmenopausal women with primary headaches.

Journal: Menopause (New York, N.Y.) 20060101

Title: Breast cancer risk associated with different HRT formulations: a register-based case-control study.

Journal: BMC women's health 20060101

Title: Tibolone for the treatment of moderate to severe vasomotor symptoms and genital atrophy in postmenopausal women: a multicenter, randomized, double-blind, placebo-controlled study.

Journal: Menopause (New York, N.Y.) 20060101

Title: Conversion of tibolone to 7alpha-methyl-ethinyl estradiol using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry: interpretation and clinical implications.

Journal: Menopause (New York, N.Y.) 20060101

Title: Effects of 17beta-estradiol, progesterone, synthetic progestins, tibolone, and raloxifene on vascular endothelial growth factor and Thrombospondin-1 messenger RNA in breast cancer cells.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

Title: [The benefits and risks of hormonal replacement therapy--an update].

Journal: Gynakologisch-geburtshilfliche Rundschau 20060101

Title: [Breast histologic changes in female rats treated with sex steroids].

Journal: Revista da Associacao Medica Brasileira (1992) 20060101

Title: Effect of tibolone therapy on lipids and coagulation indices.

Journal: Clinical chemistry and laboratory medicine 20060101

Title: Effect of tibolone on cytochrome c oxidase I, beta-2-microglobulin and vascular endothelial growth factor gene expression in the lower urinary tract of castrated rats.

Journal: Clinical and experimental obstetrics & gynecology 20060101

Title: Effects of tibolone on abdominal subcutaneous fat, serum leptin levels, and anthropometric indices: a 6-month, prospective, randomized, placebo-controlled, double-blind study.

Journal: Advances in therapy 20060101

Title: Therapeutic effects of progestins, androgens, and tibolone for menopausal symptoms.

Journal: The American journal of medicine 20051219

Title: Stereoselectivity in metabolic 3-reduction of tibolone in healthy Chinese female volunteers.

Journal: Acta pharmacologica Sinica 20051201

Title: Managing the menopause: British Menopause Society Council consensus statement on hormone replacement therapy.

Journal: The journal of the British Menopause Society 20051201

Title: Effects of hormone therapy on C-reactive protein and IL-6 in postmenopausal women: a review article.

Journal: Climacteric : the journal of the International Menopause Society 20051201

Title: Clinical effects of tibolone in postmenopausal women after 5 years of tamoxifen therapy for breast cancer.

Journal: Climacteric : the journal of the International Menopause Society 20051201

Title: Cyclooxygenase-2 expression in endometrial polyps during menopause.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20051201

Title: Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: Evidence of progestogenic effects.

Journal: Steroids 20051101

Title: Mood scores in relation to hormone replacement therapies during menopause: a prospective randomized trial.

Journal: The Tohoku journal of experimental medicine 20051101

Title: LIFT study to continue as planned.

Journal: BMJ (Clinical research ed.) 20051008

Title: Efficacy of tibolone and transdermal estrogen therapy on psychological symptoms in women following surgical menopause.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20051001

Title: Gynecologists' attitudes towards hormone therapy in the post 'Women's Health Initiative' study era.

Journal: Maturitas 20050916

Title: Two hormone replacement therapy (HRT) regimens for middle-eastern postmenopausal women.

Journal: Maturitas 20050916

Title: Hormone replacement therapy (HRT) and endometrial morphology under consideration of the different molecular pathways in endometrial carcinogenesis.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050901

Title: Effects of oestrogen receptor-active compounds on lipid metabolism.

Journal: Diabetes, obesity & metabolism 20050901

Title: The Million Women Study--is it believable?

Journal: Climacteric : the journal of the International Menopause Society 20050901

Title: The long-term effects of tibolone on aortic stiffness and endothelial function.

Journal: Climacteric : the journal of the International Menopause Society 20050901

Title: Apoptosis and proliferation in breast cancer cells, cultured in vitro: effects of SERMs.

Journal: Climacteric : the journal of the International Menopause Society 20050901

Title: Pharmacologic treatment options for hypoactive sexual desire disorder.

Journal: Women's health (London, England) 20050901

Title: Endometrial cancer--surprising reports.

Journal: Maturitas 20050816

Title: Effects of tibolone on body composition in postmenopausal women: a 1-year follow up study.

Journal: Maturitas 20050816

Title: Effect of different preparations of hormone therapy on lipid and glucose metabolism, coagulation factors, and bone mineral density in overweight and obese postmenopausal women.

Journal: Fertility and sterility 20050801

Title: Effect of 17 beta-estradiol, progesterone, synthetic progestins, tibolone, and tibolone metabolites on vascular endothelial growth factor mRNA in breast cancer cells.

Journal: Fertility and sterility 20050801

Title: Assessment of DNA damage in postmenopausal women under hormone replacement therapy.

Journal: Maturitas 20050716

Title: Does tibolone affect serum leptin levels and body weight in postmenopausal women?

Journal: Archives of gynecology and obstetrics 20050701

Title: Significant differential effects of lower doses of hormone therapy or tibolone on markers of cardiovascular disease in post-menopausal women: a randomized, double-blind, crossover study.

Journal: European heart journal 20050701

Title: Endometrial adenocarcinoma after prolonged tibolone therapy.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20050701

Title: The effects of hormone therapy, estrogen therapy and tibolone on apoptosis and cyclin D1 expression in postmenopausal vaginal epithelium.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050701

Title: Expression of proliferating cell nuclear antigen and bcl-2 during a pseudomenopausal state induced by presurgical treatment of uterine leiomyomas with gonadotropin-releasing hormone analogues plus tibolone.

Journal: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 20050701

Title: Expression of p53 and markers for apoptosis in breast tissue during long-term hormone therapy in cynomolgus monkeys.

Journal: American journal of obstetrics and gynecology 20050701

Title: Endometrial cancer and hormone-replacement therapy.

Journal: Lancet (London, England) 20050701

Title: Endometrial cancer and hormone-replacement therapy.

Journal: Lancet (London, England) 20050701

Title: Treatment of menopausal symptoms: what shall we do now?

Journal: Lancet (London, England) 20050701

Title: [Clinical trial on the effectiveness and safety of triptorelin in treatment of uterine leiomyoma].

Journal: Zhonghua fu chan ke za zhi 20050701

Title: Is mammographic density, as currently measured, a robust surrogate marker for breast cancer?

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050701

Title: The need for tissue selective menopausal agents.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050701

Title: Presentations of endometrial activity after curative radiotherapy for cervical cancer.

Journal: Maturitas 20050616

Title: Postmenopausal osteoporosis: therapeutic options.

Journal: Climacteric : the journal of the International Menopause Society 20050601

Title: Menopausal symptoms.

Journal: Clinical evidence 20050601

Title: [Tibolone treatment of diabetic postmenopausal women: clinical and laboratory safety parameters].

Journal: Arquivos brasileiros de endocrinologia e metabologia 20050601

Title: Tibolone: clinical recommendations and practical guidelines. A report of the International Tibolone Consensus Group.

Journal: Maturitas 20050516

Title: Postmenopausal hormone therapy: from monkey glands to transdermal patches.

Journal: The Journal of endocrinology 20050501

Title: Female sexual dysfunction and use of hormone therapy in postmenopausal women.

Journal: Seminars in reproductive medicine 20050501

Title: Magnetic resonance spectroscopic comparison of the effects of resveratrol (3,4',5-trihydroxy stilbene) to conjugated equine estrogen, tibolone and raloxifene on ovariectomized rat brains.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050501

Title: Fibroids (uterine myomatosis, leiomyomas).

Journal: American family physician 20050501

Title: Effects of menopause and tibolone on antioxidants in postmenopausal women.

Journal: Annals of clinical biochemistry 20050501

Title: Differential effects of alternatives to hormone replacement therapy in postmenopausal healthy women.

Journal: Danish medical bulletin 20050501

Title: Assessment and management of women's sexual dysfunctions: problematic desire and arousal.

Journal: The journal of sexual medicine 20050501

Title: Vascular reactivity and atheromatous plaques in post-menopausal women on tibolone treatment. Open prospective study with Doppler ultrasonography in internal carotid artery.

Journal: Maturitas 20050411

Title: Different effect of hormone replacement therapy, DHEAS and tibolone on endothelial function in postmenopausal women with increased cardiovascular risk.

Journal: Maturitas 20050411

Title: Serum androgen levels and insulin resistance in postmenopausal women: association with hormone therapy, tibolone and raloxifene.

Journal: Maturitas 20050411

Title: A comparative study of efficacy of tibolone and simvastatin on atherosclerosis in ovariectomized cholesterol-fed rabbits.

Journal: Maturitas 20050411

Title: Hormone use for menopausal symptoms and risk of breast cancer. A Danish cohort study.

Journal: British journal of cancer 20050411

Title: Progestins and recurrence in breast cancer survivors.

Journal: Journal of the National Cancer Institute 20050406

Title: Effect of tamoxifen, raloxifen and tibolon on bile components in ovariectomized rats.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20050401

Title: Leuprolide acetate treatment with and without coadministration of tibolone in premenopausal women with menstrual cycle-related irritable bowel syndrome.

Journal: Fertility and sterility 20050401

Title: Hormones and endometrial cancer--new data from the Million Women Study.

Journal: Lancet (London, England) 20050401

Title: Endometrial cancer and hormone-replacement therapy in the Million Women Study.

Journal: Lancet (London, England) 20050401

Title: Hormone replacement therapy--differing guidelines.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20050401

Title: Effect on sexual life--a comparison between tibolone and continuous combined conjugated equine estrogens and medroxyprogesterone acetate.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050401

Title: Tibolone relieves climacteric symptoms in highly symptomatic women with at least seven hot flushes and sweats per day.

Journal: Maturitas 20050314

Title: The role of hormone replacement therapy in endometrial polyp formation.

Journal: Maturitas 20050314

Title: Tibolone, transdermal estradiol or oral estrogen-progestin therapies: effects on circulating allopregnanolone, cortisol and dehydroepiandrosterone levels.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050301

Title: Molecular portrait of the progestagenic and estrogenic actions of tibolone: behavior of cellular networks in response to tibolone.

Journal: The Journal of clinical endocrinology and metabolism 20050201

Title: Preoperative administration of GnRH-a plus tibolone to premenopausal women with uterine fibroids: evaluation of the clinical response, the immunohistochemical expression of PDGF, bFGF and VEGF and the vascular pattern.

Journal: Steroids 20050201

Title: Drugs used to treat osteoporosis: the critical need for a uniform nomenclature based on their action on bone remodeling.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050201

Title: The effect of tibolone in postmenopausal women receiving tamoxifen after surgery for breast cancer: a randomised, double-blind, placebo-controlled trial.

Journal: BJOG : an international journal of obstetrics and gynaecology 20050201

Title: Effects of tibolone on the quality of life, anxiety-depression levels and cognitive functions in natural menopause: an observational follow-up study.

Journal: The Australian & New Zealand journal of obstetrics & gynaecology 20050201

Title: Bone health in women with early-stage breast cancer.

Journal: Clinical breast cancer 20050201

Title: Psychological effects of tibolone and sequential estrogen-progestogen therapy in perimenopausal women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050201

Title: Different effects of tibolone and continuous combined estrogen plus progestogen hormone therapy on sex hormone binding globulin and free testosterone levels--an association with mammographic density.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050201

Title: Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer.

Journal: The Journal of steroid biochemistry and molecular biology 20050201

Title: The nature of inhibition of steroid sulphatase activity by tibolone and its metabolites.

Journal: The Journal of steroid biochemistry and molecular biology 20050201

Title: p-Toluenesulfonyl isocyanate as a novel derivatization reagent to enhance the electrospray ionization and its application in the determination of two stereo isomers of 3-hydroxyl-7-methyl-norethynodrel in plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125

Title: Nitric oxide in postmenopausal women taking three different HRT regimens.

Journal: Maturitas 20050110

Title: Effects of two continuous hormone therapy regimens on C-reactive protein and homocysteine.

Journal: Menopause (New York, N.Y.) 20050101

Title: Tibolone and endometrial cancer: a cohort and nested case-control study in the UK.

Journal: Drug safety 20050101

Title: Endothelium-dependent dilatory effects of 3alpha-OH-tibolone in gracilis muscle arterioles of the female Wistar rat.

Journal: Menopause (New York, N.Y.) 20050101

Title: Effects of resveratrol, raloxifene, tibolone and conjugated equine estrogen on vaginal squamous cell maturation of ovariectomized rats.

Journal: Gynecologic and obstetric investigation 20050101

Title: Interleukin-6 and flow-mediated dilatation as markers of increased vascular inflammation in women receiving hormone therapy.

Journal: Menopause (New York, N.Y.) 20050101

Title: Hormonal environment in the induction of breast cancer in castrated rats using dimethylbenzanthracene: influence of the presence or absence of ovarian activity and of treatment with estradiol, tibolone, and raloxifene.

Journal: Menopause (New York, N.Y.) 20050101

Title: Effect of tibolone on turnover of cholesterol to bile acids in ovariectomized rats.

Journal: Menopause (New York, N.Y.) 20050101

Title: Effects of tibolone on bone quality in ovariectomized monkeys.

Journal: Menopause (New York, N.Y.) 20050101

Title: In vivo and in vitro estrogenic and progestagenic actions of Tibolone.

Journal: Biological research 20050101

Title: Therapy for menopausal symptoms during and after treatment for breast cancer : safety considerations.

Journal: Drug safety 20050101

Title: Hormonal effects on the mammary gland of postmenopausal nonhuman primates.

Journal: Breast disease 20050101

Title: Hereditary Breast-Ovarian Cancer Team of the University Medical Centre Groningen (UMCG) - a Report.

Journal: Hereditary cancer in clinical practice 20050101

Title: Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid.

Journal: Molecular pharmacology 20041201

Title: Fibroids (uterine myomatosis, leiomyomas).

Journal: Clinical evidence 20041201

Title: Tibolone and its metabolites acutely relax rabbit coronary arteries in vitro.

Journal: Maturitas 20041115

Title: [Menopause in 2004: 'hormone replacement therapy' is not what it used to be anymore].

Journal: La Revue de medecine interne 20041101

Title: Long-term effects of tibolone on mammographic density.

Journal: Fertility and sterility 20041101

Title: Transvaginal ultrasonographic assessment of the endometrium in asymptomatic, postmenopausal women using different HRT regimens containing tibolone or estrogen.

Journal: The Journal of reproductive medicine 20041101

Title: Effect of hormone replacement therapy on the elemental contents of uterine tissue.

Journal: Biological trace element research 20041001

Title: [Menopausal hormonal therapies: impact on mammographic breast density].

Journal: Journal de radiologie 20041001

Title: Hormones and mammographic breast density.

Journal: Maturitas 20040924

Title: Tissue-selective effects of tibolone on the breast.

Journal: Maturitas 20040924

Title: The effects of tibolone and oestrogen-based HT on breast cell proliferation and mammographic density.

Journal: Maturitas 20040924

Title: Postmenopausal hormone therapy before and after breast cancer: clinical experiences.

Journal: Maturitas 20040924

Title: Tibolone activates nitric oxide synthesis in human endothelial cells.

Journal: The Journal of clinical endocrinology and metabolism 20040901

Title: Osteoporosis in Korea.

Journal: Clinical calcium 20040901

Title: Long-term effects of tibolone on the endometrium as assessed by bleeding episodes, transvaginal scan and endometrial biopsy.

Journal: Climacteric : the journal of the International Menopause Society 20040901

Title: Tibolone: how does its mechanism of action translate into clinical effects.

Journal: Maturitas 20040830

Title: Tibolone: a selective tissue estrogenic activity regulator (STEAR).

Journal: Maturitas 20040830

Title: Role of enzymes and tissue-specific actions of steroids.

Journal: Maturitas 20040830

Title: Multisystem evaluations of the long-term effects of tibolone on postmenopausal monkeys.

Journal: Maturitas 20040830

Title: Tissue-selectivity: the mechanism of action of tibolone.

Journal: Maturitas 20040830

Title: Comparison of the effects of tibolone and estrogen replacement therapy on echocardiographic basic cardiac functions in post-menopausal women: a randomized placebo controlled study.

Journal: Maturitas 20040820

Title: Tibolone, oral or transdermal hormone replacement and colour Doppler analysis: a prospective, randomised pilot study.

Journal: Maturitas 20040820

Title: Breast cancer with different prognostic characteristics developing in Danish women using hormone replacement therapy.

Journal: British journal of cancer 20040816

Title: Effect of hormone therapy, tibolone and raloxifene on circulating vascular endothelial growth factor in Greek postmenopausal women.

Journal: European journal of endocrinology 20040801

Title: Effect of hormone replacement therapy and tibolone on serum leptin levels in postmenopausal women.

Journal: Maturitas 20040615

Title: Prolonged use of gonadotropin-releasing hormone agonist and tibolone as add-back therapy for the treatment of endometrial hyperplasia.

Journal: Maturitas 20040615

Title: Mammographic breast density changes after 1 year of tibolone use.

Journal: Maturitas 20040615

Title: Administration of tibolone decreases 24 h heart rate but not blood pressure of post-menopausal women.

Journal: Maturitas 20040615

Title: The selective estrogen enzyme modulators in breast cancer: a review.

Journal: Biochimica et biophysica acta 20040607

Title: Tibolone.

Journal: Acta obstetricia et gynecologica Scandinavica 20040601

Title: Hormone therapy after endometrial cancer.

Journal: Endocrine-related cancer 20040601

Title: Effect of tibolone on markers of cardiovascular disease risk in postmenopausal women undergoing hemodialysis: a pilot study.

Journal: Fertility and sterility 20040601

Title: The HORIZON Recurrent Fracture Trial: design of a clinical trial in the prevention of subsequent fractures after low trauma hip fracture repair.

Journal: Current medical research and opinion 20040601

Title: Post-menopausal hormone replacement therapy (cont'd): risk-benefit balance in the hot seat.

Journal: Prescrire international 20040601

Title: Clinical background of women prescribed tibolone or combined estrogen + progestogen therapies: a UK MediPlus study.

Journal: Climacteric : the journal of the International Menopause Society 20040601

Title: Menopausal symptoms.

Journal: Clinical evidence 20040601

Title: Increased risk of breast cancer following different regimens of hormone replacement therapy frequently used in Europe.

Journal: International journal of cancer 20040501

Title: Tibolone: a unique version of hormone replacement therapy.

Journal: The Annals of pharmacotherapy 20040501

Title: Carcinoma of the endometrium in patients treated with tibolone.

Journal: Gynecologic oncology 20040501

Title: Effects of tibolone and cyclic hormone replacement therapy on glucose metabolism in non-diabetic obese postmenopausal women: a randomized study.

Journal: European journal of endocrinology 20040501

Title: [Alternatives to hormone replacement therapy for menopause: an epidemiological evaluation].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20040501

Title: Evaluation of the effect of tibolone and transdermal estradiol on triglyceride level in hypertriglyceridemic and normotriglyceridemic postmenopausal women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040501

Title: Effect of hormone replacement therapy, tibolone and raloxifene on serum lipids, apolipoprotein A1, apolipoprotein B and lipoprotein(a) in Greek postmenopausal women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040501

Title: By the way, doctor. What happened to tibolone--the estrogen alternative we heard about a while ago? Did it turn out not to be effective?

Journal: Harvard women's health watch 20040401

Title: A review of the effects of tibolone on the skeleton.

Journal: Expert opinion on pharmacotherapy 20040401

Title: Sulfation of tibolone and tibolone metabolites by expressed human cytosolic sulfotransferases.

Journal: The Journal of steroid biochemistry and molecular biology 20040401

Title: [Effects of hormonal replacement therapy on breast density in postmenopausal women].

Journal: Minerva ginecologica 20040401

Title: Do lipid profiles of postmenopausal women under oral hormone replacement therapy remain stable or reveal a multiphasic course in time?

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040401

Title: The influence of 5-year therapy with tibolone on the lipid profile in postmenopausal women with mild hypercholesterolemia.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040401

Title: The effect of tibolone on bone mineral density in postmenopausal women with osteopenia or osteoporosis--8 years follow-up.

Journal: Maturitas 20040315

Title: Effects of tibolone and continuous combined hormone therapy on mammographic breast density and breast histochemical markers in postmenopausal women.

Journal: Fertility and sterility 20040301

Title: Personal use of HRT by postmenopausal women doctors and doctors' wives in the north of Italy.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040301

Title: A comparative study of breast cell proliferation during hormone replacement therapy: effects of tibolon and continuous combined estrogen-progestogen treatment.

Journal: Climacteric : the journal of the International Menopause Society 20040301

Title: Changes in bone turnover during tibolone treatment.

Journal: Maturitas 20040220

Title: Tibolone and its metabolites induce antimitogenesis in human coronary artery smooth muscle cells: role of estrogen, progesterone, and androgen receptors.

Journal: The Journal of clinical endocrinology and metabolism 20040201

Title: [Tibolone].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040201

Title: Acute actions of 3 alpha-hydroxy-tibolone on factors influencing contraction in guinea-pig ventricular myocytes.

Journal: European journal of pharmacology 20040126

Title: Effect of hormone replacement therapy and tibolone on serum total homocysteine levels in postmenopausal women.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20040115

Title: [Postmenopausal osteoporosis].

Journal: Orvosi hetilap 20040104

Title: Observational study on the efficacy of tibolone in counteracting early carotid atherosclerotic lesions in postmenopausal women.

Journal: Hormone research 20040101

Title: Patients' and clinicians' attitudes after the Women's Health Initiative study.

Journal: Menopause (New York, N.Y.) 20040101

Title: Effect of tibolone and its metabolites on vascular endothelial growth factor isoforms 121 and 165 and thrombospondin-1 mRNA in Ishikawa cells.

Journal: Menopause (New York, N.Y.) 20040101

Title: Hormone therapy after endometrial cancer.

Journal: Arzneimittel-Forschung 20040101

Title: Positive effect of treatment with synthetic steroid hormone tibolon on intimal hyperplasia and restenosis after experimental endothelial injury of rabbit carotid artery.

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20040101

Title: Red-clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165].

Journal: Breast cancer research : BCR 20040101

Title: A longitudinal evaluation of the effect of two doses of tibolone on bone density and metabolism in early postmenopausal women.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040101

Title: Hormone therapy after endometrial cancer.

Journal: Hormone research 20040101

Title: [Effects of the hormone replacement therapy on cardiovascular system, bone mass and memory in climacteric patients].

Journal: Ginecologia y obstetricia de Mexico 20040101

Title: A randomized, placebo-controlled, crossover study of tibolone (Livial) on menopause symptoms, psychological well-being, and dyadic relationship of postmenopausal Chinese women and their spouses.

Journal: Menopause (New York, N.Y.) 20040101

Title: Endometrial assessment in women using tibolone or placebo: 1-year randomized trial and 2-year observational study.

Journal: Menopause (New York, N.Y.) 20040101

Title: The effects of hormone replacement therapy on ocular surface and tear function tests in postmenopausal women.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20040101

Title: Mammographic changes during postmenopausal hormonal replacement therapy with tibolone.

Journal: European journal of gynaecological oncology 20040101

Title: Strategies for managing breast cancer risk after the menopause.

Journal: Treatments in endocrinology 20040101

Title: Hormone replacement therapy, selective estrogen receptor modulators, and tissue-specific compounds: cardiovascular effects and clinical implications.

Journal: Treatments in endocrinology 20040101

Title: Differential effects of progestins on breast tissue enzymes.

Journal: Maturitas 20031210

Title: Differential effects of progestogens on breast cancer cell lines.

Journal: Maturitas 20031210

Title: Effects of low-dose 17-beta-estradiol plus norethisterone acetate and tibolone on fasting plasma homocysteine levels in postmenopausal women.

Journal: Acta obstetricia et gynecologica Scandinavica 20031201

Title: The Osteoporosis Prevention and Arterial effects of tiboLone (OPAL) study: design and baseline characteristics.

Journal: Controlled clinical trials 20031201

Title: Serum leptin levels in patients with premenstrual syndrome treated with GnRH analogues alone and in association with tibolone.

Journal: Clinical endocrinology 20031201

Title: Hormone replacement therapy and the breast.

Journal: Surgical oncology 20031201

Title: Some comments on the Million Women Study.

Journal: Climacteric : the journal of the International Menopause Society 20031201

Title: Hormone therapy after endometrial cancer.

Journal: The journal of the British Menopause Society 20031201

Title: Menopausal symptoms.

Journal: Clinical evidence 20031201

Title: The effects of hormone replacement therapy type on pulmonary functions in postmenopausal women.

Journal: Maturitas 20031120

Title: Issues to debate on the Women's Health Initiative (WHI) study. Prescription attitudes among Belgian gynaecologists after premature discontinuation of the WHI study.

Journal: Human reproduction (Oxford, England) 20031101

Title: Serum leptin as a determinant of bone resorption in healthy postmenopausal women.

Journal: Bone 20031101

Title: Breast cancer and hormone-replacement therapy in the Million Women Study.

Journal: Maturitas 20031020

Title: The sound of an International anti-HRT herald.

Journal: Maturitas 20031020

Title: Breast cancer and hormone-replacement therapy: the Million Women Study.

Journal: Lancet (London, England) 20031018

Title: Breast cancer and hormone-replacement therapy: the Million Women Study.

Journal: Lancet (London, England) 20031018

Title: Significant differential effects of hormone therapy or tibolone on markers of cardiovascular disease in postmenopausal women: a randomized, double-blind, placebo-controlled, crossover study.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20031001

Title: [Menopause: towards treatment 'à la carte' ].

Journal: Annales d'endocrinologie 20031001

Title: [Differential effects on serum IGF-1 of tibolone (5 mg/day) vs combined continuous estrogen/progestagen in post menopausal women].

Journal: Revista medica de Chile 20031001

Title: The Million Women Study and breast cancer.

Journal: Maturitas 20030925

Title: [Breast cancer and the use of the hormones around the menopause].

Journal: Nederlands tijdschrift voor geneeskunde 20030920

Title: Serum cholesterol efflux potential is an independent predictor of coronary artery atherosclerosis.

Journal: Atherosclerosis 20030901

Title: Effects of tibolone and conjugated equine estrogens with or without medroxyprogesterone acetate on body composition and fasting carbohydrate measures in surgically postmenopausal monkeys.

Journal: Metabolism: clinical and experimental 20030901

Title: The treatment of Sjögren's syndrome with tibolone: a case report.

Journal: American journal of obstetrics and gynecology 20030901

Title: Low dose hormone therapy in reproductive endocrinology in China.

Journal: Chinese medical journal 20030901

Title: Acute effects of tibolone on cerebral vascular reactivity in vitro.

Journal: Climacteric : the journal of the International Menopause Society 20030901

Title: [Chemoprevention of breast cancer: a literature review and report on the current status in Germany].

Journal: Zentralblatt fur Gynakologie 20030901

Title: Effect of tibolone on breast symptoms resulting from postmenopausal hormone replacement therapy.

Journal: Maturitas 20030820

Title: [Treatment of osteoporosis].

Journal: Orvosi hetilap 20030803

Title: Effects of specific post-menopausal hormone therapies on bone mineral density in post-menopausal women: a meta-analysis.

Journal: Human reproduction (Oxford, England) 20030801

Title: Changes in body composition during post-menopausal hormone therapy: a 2 year prospective study.

Journal: Human reproduction (Oxford, England) 20030801

Title: Interaction between hormone replacement therapy preparations and oral anticoagulant therapy.

Journal: BJOG : an international journal of obstetrics and gynaecology 20030801

Title: Present and future pharmacotherapy for osteoporosis.

Journal: Drugs of today (Barcelona, Spain : 1998) 20030801

Title: Differential effects of unopposed versus opposed hormone therapy, tibolone, and raloxifene on substance p levels.

Journal: Fertility and sterility 20030701

Title: Menopause: new therapies.

Journal: The Medical journal of Australia 20030616

Title: Older women's sexuality.

Journal: The Medical journal of Australia 20030616

Title: Effects of short-time (3 months) tibolone treatment on bone turnover in postmenopausal women.

Journal: Archives of gynecology and obstetrics 20030601

Title: New markers for cardiovascular disease risk in women: impact of endogenous estrogen status and exogenous postmenopausal hormone therapy.

Journal: The Journal of clinical endocrinology and metabolism 20030601

Title: Hormone replacement therapy in postmenopausal women with benign fibrocystic mastopathy.

Journal: Climacteric : the journal of the International Menopause Society 20030601

Title: Evaluation of tibolone effect on arterial resistance in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20030601

Title: Serum lipids and apolipoproteins in Greek postmenopausal women: association with estrogen, estrogen-progestin, tibolone and raloxifene therapy.

Journal: Journal of endocrinological investigation 20030601

Title: Does the beneficial effect of HRT on endothelial function depend on lipid changes.

Journal: Maturitas 20030530

Title: Effects of estradiol, cyproterone acetate, tibolone and raloxifene on uterus and aorta atherosclerosis in oophorectomized cholesterol-fed rabbits.

Journal: Maturitas 20030530

Title: Treatment with hormone replacement therapy lowers remnant lipoprotein particles in healthy postmenopausal women: results from a randomized trial.

Journal: European journal of clinical investigation 20030501

Title: Progestogenic effects of tibolone on human endometrial cancer cells.

Journal: The Journal of clinical endocrinology and metabolism 20030501

Title: Cognitive function variations in postmenopausal women treated with continuous, combined HRT or tibolone. A comparison.

Journal: The Journal of reproductive medicine 20030501

Title: [Tibolone therapy in postmenopausal women with a history of many risk factors].

Journal: Orvosi hetilap 20030413

Title: Hot flashes. A closer look at causes and remedies.

Journal: Mayo Clinic women's healthsource 20030401

Title: Novel therapies for osteoporosis.

Journal: Expert opinion on investigational drugs 20030401

Title: Effects of hormone replacement therapy on mammographic findings.

Journal: Archives of gynecology and obstetrics 20030401

Title: Postmenopausal hormone therapy: cardiovascular risks.

Journal: Prescrire international 20030401

Title: Hormone replacement therapy: current controversies.

Journal: Clinical endocrinology 20030301

Title: Tibolone is not converted by human aromatase to 7alpha-methyl-17alpha-ethynylestradiol (7alpha-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS.

Journal: Steroids 20030301

Title: New anabolic therapies in osteoporosis.

Journal: Endocrinology and metabolism clinics of North America 20030301

Title: Hormone therapy and venous thromboembolism.

Journal: Best practice & research. Clinical endocrinology & metabolism 20030301

Title: Effect of tibolone treatment on intima-media thickness and the resistive indices of the carotid arteries.

Journal: Fertility and sterility 20030201

Title: Atypical endometrial hyperplasia in an 18-year-old woman.

Journal: Archives of gynecology and obstetrics 20030201

Title: [Hormone replacement therapy after breast cancer. Yes...or no?].

Journal: Revue medicale de Liege 20030201

Title: Receptor profiling and endocrine interactions of tibolone.

Journal: Steroids 20030101

Title: Tibolone lowers high density lipoprotein cholesterol by increasing hepatic lipase activity but does not impair cholesterol efflux.

Journal: Clinical endocrinology 20030101

Title: Tibolone was associated with an increase in 7 alpha-methyl-ethinylestradiol.

Journal: Menopause (New York, N.Y.) 20030101

Title: Tibolone was associated with an increase in 7 alpha-methyl-ethinylestradiol.

Journal: Menopause (New York, N.Y.) 20030101

Title: Female sexual dysfunction in postmenopausal women: systematic review of placebo-controlled trials.

Journal: American journal of obstetrics and gynecology 20030101

Title: Effects of tibolone on human breast cancer cells and human vascular coronary cells.

Journal: Archives of gynecology and obstetrics 20030101

Title: Failure of tibolone to potentiate the pharmacological effect of fluoxetine in postmenopausal major depression.

Journal: Journal of women's health (2002) 20030101

Title: Effects of tibolone on cell adhesion molecules in postmenopausal women.

Journal: Menopause (New York, N.Y.) 20030101

Title: [The effects of hormone replacement therapy in menopause on symptoms of anxiety and depression].

Journal: Turk psikiyatri dergisi = Turkish journal of psychiatry 20030101

Title: Tibolone.

Journal: Menopause (New York, N.Y.) 20030101

Title: The short-term effects of different regimens of hormone replacement therapy on left ventricular structure and performance in healthy postmenopausal women. A prospective, controlled echocardiographic study.

Journal: Gynecologic and obstetric investigation 20030101

Title: Apoptosis in the endometrium of postmenopausal women receiving tibolone.

Journal: Gynecologic and obstetric investigation 20030101

Title: [GnRH agonist and add back therapy--indications, results and problems in the treatment of genital endometriosis].

Journal: Zentralblatt fur Gynakologie 20030101

Title: Tibolone and risk of endometrial polyps: a prospective, comparative study with hormone therapy.

Journal: Menopause (New York, N.Y.) 20030101

Title: [Sex hormones and female sexuality].

Journal: Medicinski pregled 20030101

Title: Efficacy and safety of oral tibolone 1.25 or 2.5 mg/day vs. placebo in postmenopausal women.

Journal: European review for medical and pharmacological sciences 20030101

Title: Tibolone inhibits aortic atherosclerotic lesionformation in oophorectomized cholesterol-fed rabbits.

Journal: Experimental and clinical cardiology 20030101

Title: [Hormone replacement and breast carcinoma].

Journal: Praxis 20021211

Title: Differential effects of selective estrogen receptor modulators and estrogens on mammary blood flow in the ovine.

Journal: American journal of obstetrics and gynecology 20021201

Title: Hormone replacement therapy in women with a history of breast cancer.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20021201

Title: Ten years of treatment with tibolone 2.5 mg daily: effects on bone loss in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20021201

Title: Pros and cons of existing treatment modalities in osteoporosis: a comparison between tibolone, SERMs and estrogen (+/-progestogen) treatments.

Journal: The Journal of steroid biochemistry and molecular biology 20021201

Title: Endocrine prevention of breast: any role for tibolone?

Journal: European journal of cancer (Oxford, England : 1990) 20021101

Title: Comparison of tibolone and conjugated equine estrogens effects on carotid artery atherosclerosis of postmenopausal monkeys.

Journal: Stroke 20021101

Title: Effect of tibolone administration on heart rate variability and free fatty acid levels in postmenopausal women.

Journal: Fertility and sterility 20021101

Title: Haemostatic risk factors in healthy postmenopausal women taking hormone replacement therapy.

Journal: Maturitas 20021025

Title: Effects of tibolone and combined 17beta-estradiol and norethisterone acetate on serum C-reactive protein in healthy post-menopausal women: a randomized trial.

Journal: Human reproduction (Oxford, England) 20021001

Title: Dose-response analysis of effects of tibolone on climacteric symptoms.

Journal: BJOG : an international journal of obstetrics and gynaecology 20021001

Title: Tibolone versus four estrogen replacement therapy protocols and plasma lipid levels in postmenopausal women.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20021001

Title: [Postmenopausal hormonal treatment: conventional hormone replacement therapy or tibolone? Effects on bone].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20021001

Title: [Tibolone].

Journal: Presse medicale (Paris, France : 1983) 20020907

Title: [Treatments 'substitute' to Hormonal Replacement Therapy of menopause].

Journal: Presse medicale (Paris, France : 1983) 20020907

Title: Effects of tibolone on plasma levels of nitric oxide in postmenopausal women.

Journal: Fertility and sterility 20020901

Title: What is tibolone--and is it a SPEAR?

Journal: Climacteric : the journal of the International Menopause Society 20020901

Title: Flow resistance in carotid and middle cerebral arteries in postmenopausal women: a comparative study of tibolone and continuous combined hormone replacement therapy.

Journal: Climacteric : the journal of the International Menopause Society 20020901

Title: [Tibolone].

Journal: Clinical calcium 20020901

Title: Sexuality in the climacteric years.

Journal: Maturitas 20020830

Title: Effects of tibolone on plasma homocysteine levels in postmenopausal women.

Journal: Fertility and sterility 20020801

Title: In vitro studies of tibolone in breast cells.

Journal: Fertility and sterility 20020801

Title: Effects of tibolone and continuous combined hormone replacement therapy on bleeding rates, quality of life and tolerability in postmenopausal women.

Journal: BJOG : an international journal of obstetrics and gynaecology 20020801

Title: Pharmacokinetics of tibolone in early and late postmenopausal women.

Journal: British journal of clinical pharmacology 20020801

Title: [Hormone replacement therapy and its derivatives in the prevention and treatment of osteoporosis].

Journal: Revue medicale de la Suisse romande 20020801

Title: [Clinical study of the month. Benefit/risk balance of postmenopausal estrogen-progestin treatment in peril in the Women's Health Initiative study: practical attitude of the clinician].

Journal: Revue medicale de Liege 20020801

Title: Impact of different hormone replacement therapy regimens on the size of myoma uteri in postmenopausal period: tibolone versus transdermal hormonal replacement system.

Journal: Maturitas 20020725

Title: The effect of tibolone on endometrial IGF-1 and IGFBP-1 levels in ovariectomized rats.

Journal: Maturitas 20020725

Title: [The new CBO-guideline 'Osteoporosis' is a broadly supported standard for clinical practice].

Journal: Nederlands tijdschrift voor geneeskunde 20020720

Title: [CBO guideline 'Osteoporosis' (second revision].

Journal: Nederlands tijdschrift voor geneeskunde 20020720

Title: [The Dutch College of General Practitioners practice guideline 'The menopause'; reaction of the field of general practice].

Journal: Nederlands tijdschrift voor geneeskunde 20020713

Title: Bone metabolism in postmenopausal women who were treated with a gonadotropin-releasing hormone agonist and tibolone.

Journal: Fertility and sterility 20020701

Title: Hormone replacement therapy and mammographic screening.

Journal: Clinical radiology 20020701

Title: Estrogenic effects of 7alpha-methyl-17alpha-ethynylestradiol: a newly discovered tibolone metabolite.

Journal: Steroids 20020701

Title: Novel therapeutic options for osteoporosis.

Journal: Current opinion in rheumatology 20020701

Title: Effect of tibolone (Org OD14) and its metabolites on aromatase and estrone sulfatase activity in human breast adipose stromal cells and in MCF-7 and T47D breast cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20020701

Title: Hormone replacement therapy with tibolone: effects on sexual functioning in postmenopausal women.

Journal: Acta obstetricia et gynecologica Scandinavica 20020701

Title: Tibolone: new preparation. Menopausal symptoms: oestrogen-progestogen combinations are still the reference treatment.

Journal: Prescrire international 20020601

Title: The role of ERT/HRT.

Journal: Best practice & research. Clinical obstetrics & gynaecology 20020601

Title: Menopausal symptoms.

Journal: Clinical evidence 20020601

Title: Treatment of depression associated with the menstrual cycle: premenstrual dysphoria, postpartum depression, and the perimenopause.

Journal: Dialogues in clinical neuroscience 20020601

Title: Short-term administration of tibolone plus GnRH analog before laparoscopic myomectomy.

Journal: The Journal of the American Association of Gynecologic Laparoscopists 20020501

Title: A cross-sectional study of the effects of hormon replacement therapy on the cardiovascular disease risk profile in healthy postmenopausal women.

Journal: Fertility and sterility 20020501

Title: Menopause. HRT: looking for something better.

Journal: Harvard health letter 20020501

Title: Prospective, randomised study with three HRT regimens in postmenopausal women with an intact uterus.

Journal: Maturitas 20020425

Title: Serum cholesterol efflux potential in postmenopausal monkeys treated with tibolone or conjugated estrogens.

Journal: Metabolism: clinical and experimental 20020401

Title: Effects of tibolone and continuous combined hormone replacement therapy on mammographic breast density.

Journal: American journal of obstetrics and gynecology 20020401

Title: [Tibolone-induced hepatotoxicity].

Journal: Gastroenterologia y hepatologia 20020401

Title: Combination treatment of osteoporosis: a clinical review.

Journal: Journal of women's health & gender-based medicine 20020401

Title: Effect of a standardized meal on the bioavailability of a single oral dose of tibolone 2.5 mg in healthy postmenopausal women.

Journal: Pharmacotherapy 20020301

Title: Therapeutic interventions in osteoporosis.

Journal: Nursing times 20020301

Title: A randomized, open-label study of conjugated equine estrogens plus medroxyprogesterone acetate versus tibolone: effects on symptom control, bleeding pattern, lipid profile and tolerability.

Journal: Climacteric : the journal of the International Menopause Society 20020301

Title: [Drugs in development for the treatment of osteoporosis: Tibolone].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020301

Title: Randomized, double-masked, 2-year comparison of tibolone with 17beta-estradiol and norethindrone acetate in preventing postmenopausal bone loss.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20020301

Title: [Clinical aspects of Livial in postmenopausal replacement therapy].

Journal: Ginekologia polska 20020301

Title: Effect of tibolone compared with sequential hormone replacement therapy on carbohydrate metabolism in postmenopausal women.

Journal: Maturitas 20020226

Title: The in vivo human metabolism of tibolone.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020201

Title: Cognitive effects of 10 years of hormone-replacement therapy with tibolone.

Journal: Journal of clinical psychopharmacology 20020201

Title: Tibolone and 5alpha-dihydrotestosterone alone or in combination with an antiandrogen in a rat breast tumour model.

Journal: European journal of cancer (Oxford, England : 1990) 20020201

Title: Tibolone does not affect muscle power and functional ability in healthy postmenopausal women.

Journal: Clinical science (London, England : 1979) 20020201

Title: Effect of renal impairment on the pharmacokinetics of a single oral dose of tibolone 2.5 mg in early postmenopausal women.

Journal: Pharmacotherapy 20020201

Title: The effect of tibolone on the lipoprotein profile of postmenopausal women with type III hyperlipoproteinemia.

Journal: Journal of internal medicine 20020201

Title: Selective modulation of sex steroids.

Journal: Ageing research reviews 20020201

Title: The influence of tibolone on quality of life in postmenopausal women.

Journal: Maturitas 20020130

Title: A comparison of the effects of two continuous HRT regimens on cardiovascular risk factors.

Journal: Atherosclerosis 20020101

Title: Tibolone for postmenopausal women: systematic review of randomized trials.

Journal: The Journal of clinical endocrinology and metabolism 20020101

Title: A comparison of tibolone and hormone replacement therapy on coronary artery and myocardial function in ovariectomized atherosclerotic monkeys.

Journal: Menopause (New York, N.Y.) 20020101

Title: Dose proportionality of three different doses of tibolone.

Journal: Pharmacotherapy 20020101

Title: Effects of tibolone on thromboxane B(2) levels in postmenopausal women.

Journal: Gynecologic and obstetric investigation 20020101

Title: Therapies to improve bone mineral density and reduce the risk of fracture: clinical trial results.

Journal: The Journal of reproductive medicine 20020101

Title: Inhibition of oestrone sulphatase activity by tibolone and its metabolites.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101

Title: Muscle strength and tibolone: a randomised, double-blind, placebo-controlled trial.

Journal: BJOG : an international journal of obstetrics and gynaecology 20020101

Title: Hormone replacement therapy and breast tissue density on mammography.

Journal: Menopause (New York, N.Y.) 20020101

Title: Mammographic changes associated with raloxifene and tibolone therapy in postmenopausal women: a prospective study.

Journal: Menopause (New York, N.Y.) 20020101

Title: Effects of tibolone on endogenous nitric oxide (nitrite/nitrate levels) in postmenopausal women.

Journal: International journal of fertility and women's medicine 20020101

Title: Replacing hormones, understanding the consequences.

Journal: Menopause (New York, N.Y.) 20020101

Title: The effects of tibolone on mood and libido.

Journal: Menopause (New York, N.Y.) 20020101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: The in vivo metabolism of tibolone in animal species.

Journal: European journal of drug metabolism and pharmacokinetics 20020101

Title: Tibolone versus 17beta-estradiol/norethisterone: effects on the proliferation of human breast cancer cells.

Journal: European journal of gynaecological oncology 20020101

Title: Effects of tibolone on the development of osteopenia induced by ovariectomy in rats.

Journal: Polish journal of pharmacology 20020101

Title: Comparative effects of tibolone and conjugated equine estrogens with and without medroxyprogesterone acetate on the reproductive tract of female cynomolgus monkeys.

Journal: Menopause (New York, N.Y.) 20020101

Title: Formation of 7 alpha-methyl-ethinyl estradiol during treatment with tibolone.

Journal: Menopause (New York, N.Y.) 20020101

Title: Effects of long-term hormone replacement and of tibolone on choline acetyltransferase and acetylcholinesterase activities in the brains of ovariectomized, cynomologus monkeys.

Journal: Neuroscience 20020101

Title: Tibolone, blood pressure and obesity.

Journal: The National medical journal of India 20020101

Title: A benefit-risk assessment of medical treatment for uterine leiomyomas.

Journal: Drug safety 20020101

Title: Effects of tibolone and conventional hormone replacement therapies on arterial and hepatic cholesterol accumulation and on circulating endothelin-1, vascular cell adhesion molecule-1, and E-selectin in surgically menopausal monkeys.

Journal: Menopause (New York, N.Y.) 20020101

Title: Effects of tibolone and hormone replacement therapy on the breast of cynomolgus monkeys.

Journal: Menopause (New York, N.Y.) 20020101

Title: The effects of add-back therapy with tibolone on myoma uteri.

Journal: Clinical and experimental obstetrics & gynecology 20020101

Title: [Guidelines for drug therapy of postmenopausal osteoporosis].

Journal: Wiener medizinische Wochenschrift (1946) 20020101

Title: Hormone replacement therapy and endothelial function. Results of a randomized controlled trial in healthy postmenopausal women.

Journal: Atherosclerosis 20011201

Title: Lowering of HDL cholesterol in post-menopausal women by tibolone is not associated with changes in cholesterol efflux capacity or paraoxonase activity.

Journal: Atherosclerosis 20011201

Title: Tibolone: new type of hormone replacement.

Journal: Harvard women's health watch 20011201

Title: Effect of hormone replacement therapies and selective estrogen receptor modulators in postmenopausal women with uterine leiomyomas: a literature review.

Journal: Climacteric : the journal of the International Menopause Society 20011201

Title: Quality of life and sexuality changes in postmenopausal women receiving tibolone therapy.

Journal: Climacteric : the journal of the International Menopause Society 20011201

Title: Mammographic density increase in women receiving different hormone replacement regimens.

Journal: Maturitas 20011130

Title: Effects of different types of hormone replacement therapy on mammographic density.

Journal: Maturitas 20011130

Title: A pilot study of hormone replacement therapy with tibolone in women with mastopathic breasts.

Journal: Maturitas 20011130

Title: The effect of tibolone on fat mass, fat-free mass, and total body water in postmenopausal women.

Journal: Endocrinology 20011101

Title: A comparison of tibolone and conjugated equine estrogens effects on coronary artery atherosclerosis and bone density of postmenopausal monkeys.

Journal: The Journal of clinical endocrinology and metabolism 20011101

Title: [Effect of tibolone on vascular markers of human female coronary arteries - comparison with estradiol/norethisterone].

Journal: Zentralblatt fur Gynakologie 20011101

Title: Long term effects of Tibolone on postmenopausal women with uterine myomas.

Journal: Maturitas 20011031

Title: Tibolone: a compound with tissue specific inhibitory effects on sulfatase.

Journal: Molecular and cellular endocrinology 20011025

Title: Prevention of bone loss with tibolone in postmenopausal women: results of two randomized, double-blind, placebo-controlled, dose-finding studies.

Journal: The Journal of clinical endocrinology and metabolism 20011001

Title: Confounders?

Journal: Fertility and sterility 20011001

Title: Assessment of the effectiveness of postmenopausal tibolone therapy on neural functions by measuring visual evoked potentials: a placebo-controlled study.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20010901

Title: Mammographic density changes during different postmenopausal hormone replacement therapies.

Journal: Fertility and sterility 20010901

Title: Tibolone exerts its protective effect on trabecular bone loss through the estrogen receptor.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010901

Title: Effect of 16 months of treatment with tibolone on bone mass, turnover, and biomechanical quality in mature ovariectomized rats.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010901

Title: Use of gonadotropin-releasing hormone analog with tibolone to prevent cyclic attacks of acute intermittent porphyria.

Journal: Metabolism: clinical and experimental 20010901

Title: Effects of tibolone on the endometrium.

Journal: Climacteric : the journal of the International Menopause Society 20010901

Title: [New gestagens--advantages and disadvantages].

Journal: Therapeutische Umschau. Revue therapeutique 20010901

Title: [Effect of hormone replacement with tibolone on plasma insulin and blood glucose in postmenopause].

Journal: Ginecologia y obstetricia de Mexico 20010801

Title: Venous endothelial function in postmenopausal women after six months of tibolone therapy.

Journal: Maturitas 20010725

Title: Mammographic density changes in postmenopausal women using tibolone therapy.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20010701

Title: How to prevent fractures in the individual with osteoporosis.

Journal: Best practice & research. Clinical rheumatology 20010701

Title: Tibolone and its effects on bone: a review.

Journal: Climacteric : the journal of the International Menopause Society 20010601

Title: Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats.

Journal: European journal of pharmacology 20010504

Title: The influence of tibolone upon serum leptin levels in post-menopausal women.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20010501

Title: Effects of postmenopausal hormone replacement therapy on lipid, lipoprotein, and apolipoprotein (a) concentrations: analysis of studies published from 1974-2000.

Journal: Fertility and sterility 20010501

Title: [Clinical efficacy of burning mouth syndrome treated by livial].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20010428

Title: Short-term effects of three continuous hormone replacement therapy regimens on platelet tritiated imipramine binding and mood scores: a prospective randomized trial.

Journal: Fertility and sterility 20010401

Title: The management of osteoporosis.

Journal: The Journal of bone and joint surgery. British volume 20010401

Title: Diagnosis and treatment of osteoporosis in Brazil.

Journal: Clinical calcium 20010401

Title: Differential effects on the androgen status of postmenopausal women treated with tibolone and continuous combined estradiol and norethindrone acetate replacement therapy.

Journal: Fertility and sterility 20010301

Title: Hemodynamic response to tibolone in reproductive and nonreproductive tissues in the sheep.

Journal: American journal of obstetrics and gynecology 20010301

Title: Effects of estrogen/androgen therapy on bone mineral density parameters.

Journal: The Journal of reproductive medicine 20010301

Title: The effects of tibolone on vaginal blood flow, sexual desire and arousability in postmenopausal women.

Journal: Climacteric : the journal of the International Menopause Society 20010301

Title: Androgens and aging.

Journal: Maturitas 20010227

Title: Synthesis of (3alpha,7beta,17alpha)-7-methyl-19-norpregn-5(10)-en-20-yne-3,7,17-triol, a metabolite of ORG OD14, and its 7-epimer.

Journal: Steroids 20010201

Title: Use of leuprolide acetate plus tibolone in the treatment of severe premenstrual syndrome.

Journal: Fertility and sterility 20010201

Title: Effectiveness of short-term administration of tibolone plus gonadotropin-releasing hormone analogue on the surgical outcome of laparoscopic myomectomy.

Journal: Fertility and sterility 20010201

Title: Receptor selectivity, enzymes and tissue specificity.

Journal: Maturitas 20010131

Title: Tibolone: what does tissue specific activity mean?

Journal: Maturitas 20010131

Title: Effects of physical activity and menopausal hormone replacement therapy on postural stability in postmenopausal women--a cross-sectional study.

Journal: Maturitas 20010131

Title: Antiatherosclerotic effects of tibolone.

Journal: Menopause (New York, N.Y.) 20010101

Title: Comparison of the antiatherosclerotic effect of tibolone with that of estradiol and ethinyl estradiol in cholesterol-fed, ovariectomized rabbits.

Journal: Menopause (New York, N.Y.) 20010101

Title: The selective estrogen enzyme modulator (SEEM) in breast cancer.

Journal: The Journal of steroid biochemistry and molecular biology 20010101

Title: Tibolone: a steroid with a tissue-specific mode of action.

Journal: The Journal of steroid biochemistry and molecular biology 20010101

Title: Effects of 8 years of treatment with tibolone 2.5 mg daily on postmenopausal bone loss.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101

Title: Thyroid carcinoma after successful treatment of osteosarcoma: a report of three patients.

Journal: Journal of pediatric hematology/oncology 20010101

Title: Hot flashes: aetiology and management.

Journal: Drugs & aging 20010101

Title: Bone-resorbing cytokines from peripheral blood mononuclear cells after hormone replacement therapy: a longitudinal study.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101

Title: [Our experience in the treatment of climacteric complaints with Livial (Organon)].

Journal: Akusherstvo i ginekologiia 20010101

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Tags:5630-53-5 Molecular Formula|5630-53-5 MDL|5630-53-5 SMILES|5630-53-5 (1S,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-2(7)-en-5-one