Title: Induction of DNA damage and G2 cell cycle arrest by diepoxybutane through the activation of the Chk1-dependent pathway in mouse germ cells.
Journal: Chemical research in toxicology 20150316
Title: In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.
Journal: Chemical research in toxicology 20131118
Title: DNA damage induced by three major metabolites of 1,3-butadiene in human hepatocyte L02 cells.
Journal: Mutation research 20120918
Title: Mutation spectra of S-(2-hydroxy-3,4-epoxybutyl)glutathione: comparison with 1,3-butadiene and its metabolites in the Escherichia coli rpoB gene.
Journal: Chemical research in toxicology 20120716
Title: Conjugation of butadiene diepoxide with glutathione yields DNA adducts in vitro and in vivo.
Journal: Chemical research in toxicology 20120319
Title: Diepoxybutane interstrand cross-links induce DNA bending.
Journal: Biochimie 20120201
Title: Formation of 1,2:3,4-diepoxybutane-specific hemoglobin adducts in 1,3-butadiene exposed workers.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120101
Title: Assessment of DNA interstrand crosslinks using the modified alkaline comet assay.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: 1,2:3,4-Diepoxybutane in blood of male B6C3F1 mice and male Sprague-Dawley rats exposed to 1,3-butadiene.
Journal: Toxicology letters 20111215
Title: Diepoxybutane induces the formation of DNA-DNA rather than DNA-protein cross-links, and single-strand breaks and alkali-labile sites in human hepatocyte L02 cells.
Journal: Mutation research 20111101
Title: Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes.
Journal: Toxicology 20111028
Title: Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation.
Journal: Chemical research in toxicology 20110620
Title: Incidence of Fanconi anemia in children with congenital thumb anomalies referred for diepoxybutane testing.
Journal: The Journal of hand surgery 20110601
Title: Genotoxicity of stereoisomers of 1,2,3,4-diepoxybutane in the gpt gene of Chinese hamster ovary AS52 cells.
Journal: Bulletin of environmental contamination and toxicology 20110601
Title: Chromosome fragility in patients with Fanconi anaemia: diagnostic implications and clinical impact.
Journal: Journal of medical genetics 20110401
Title: Diepoxybutane.
Journal: Report on carcinogens : carcinogen profiles 20110101
Title: Olfactory receptor cells respond to odors in a tissue and semiconductor hybrid neuron chip.
Journal: Biosensors & bioelectronics 20101215
Title: Normal red blood cells partially decrease diepoxybutane-induced chromosome breakage in cultured lymphocytes from Fanconi anaemia patients.
Journal: Cell proliferation 20101201
Title: DNA oligomers containing site-specific and stereospecific exocyclic deoxyadenosine adducts of 1,2,3,4-diepoxybutane: synthesis, characterization, and effects on DNA structure.
Journal: Chemical research in toxicology 20101018
Title: 1,3-Butadiene: II. Genotoxicity profile.
Journal: Critical reviews in toxicology 20101001
Title: DNA-protein cross-linking by 1,2,3,4-diepoxybutane.
Journal: Journal of proteome research 20100903
Title: Fanconi anemia is characterized by delayed repair kinetics of DNA double-strand breaks.
Journal: The Tohoku journal of experimental medicine 20100501
Title: Column switching HPLC-ESI(+)-MS/MS methods for quantitative analysis of exocyclic dA adducts in the DNA of laboratory animals exposed to 1,3-butadiene.
Journal: Chemical research in toxicology 20100419
Title: Alkyltransferase-mediated toxicity of bis-electrophiles in mammalian cells.
Journal: Mutation research 20100203
Title: Clinical, genetic and cytogenetic study of Fanconi anemia in an Indian population.
Journal: Hematology (Amsterdam, Netherlands) 20100201
Title: Exocyclic deoxyadenosine adducts of 1,2,3,4-diepoxybutane: synthesis, structural elucidation, and mechanistic studies.
Journal: Chemical research in toxicology 20100118
Title: Kinetics of the reactions of isoprene-derived epoxides in model tropospheric aerosol solutions.
Journal: Environmental science & technology 20091101
Title: Cob(I)alamin for trapping butadiene epoxides in metabolism with rat S9 and for determining associated kinetic parameters.
Journal: Chemical research in toxicology 20090901
Title: Fanconi anemia and its diagnosis.
Journal: Mutation research 20090731
Title: The bis-electrophile diepoxybutane cross-links DNA to human histones but does not result in enhanced mutagenesis in recombinant systems.
Journal: Chemical research in toxicology 20090601
Title: Quantitative PCR analysis of diepoxybutane and epihalohydrin damage to nuclear versus mitochondrial DNA.
Journal: Mutation research 20090512
Title: Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the Comet assay.
Journal: Mutation research 20090512
Title: Molecular dosimetry of 1,2,3,4-diepoxybutane-induced DNA-DNA cross-links in B6C3F1 mice and F344 rats exposed to 1,3-butadiene by inhalation.
Journal: Cancer research 20090315
Title: FANCD2 Western blot as a diagnostic tool for Brazilian patients with Fanconi anemia.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090301
Title: Increased capacity of lymphocytes from hereditary hemochromatosis patients homozygous for the C282Y HFE mutation to respond to the genotoxic effect of diepoxybutane.
Journal: Mutation research 20090219
Title: Liposome-based homogeneous luminescence resonance energy transfer.
Journal: Analytical biochemistry 20090115
Title: Mechanism of diepoxybutane-induced p53 regulation in human cells.
Journal: Journal of biochemical and molecular toxicology 20090101
Title: The synthesis of 1-(4-triethoxysilyl)phenyl)-4,4,4-trifluoro-1,3-butanedione, a novel trialkoxysilane monomer for the preparation of functionalized sol-gel matrix materials.
Journal: Molecules (Basel, Switzerland) 20081020
Title: Correlation of thyroid and growth hormones to chromosomal instability in Egyptian Fanconi anemia patients.
Journal: Indian journal of pediatrics 20080701
Title: Quantitative high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis of the adenine-guanine cross-links of 1,2,3,4-diepoxybutane in tissues of butadiene-exposed B6C3F1 mice.
Journal: Chemical research in toxicology 20080501
Title: DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage.
Journal: DNA repair 20080402
Title: Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produce DNA-protein cross-links but not mutations.
Journal: Chemical research in toxicology 20080201
Title: Flow cytometry for diepoxybutane test analysis.
Journal: Genetics and molecular research : GMR 20080101
Title: Diepoxybutane activates the mitochondrial apoptotic pathway and mediates apoptosis in human lymphoblasts through oxidative stress.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20071201
Title: [Gene regulation to lactic acid bacteria for increasing production of flavor metabolite].
Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20071201
Title: Positive diepoxybutane test in a patient with Nijmegen breakage syndrome.
Journal: Pediatric blood & cancer 20070701
Title: Loss of FANCC function is associated with failure to inhibit late firing replication origins after DNA cross-linking.
Journal: Experimental cell research 20070701
Title: A ketone oximate based cyclic cationic [Ni(II)4] inverse metallacrown from simultaneous chelation and bridging of two ligands.
Journal: Dalton transactions (Cambridge, England : 2003) 20070528
Title: Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues.
Journal: Chemico-biological interactions 20070501
Title: Mutagenesis of the supF gene by stereoisomers of 1,2,3,4-diepoxybutane.
Journal: Chemical research in toxicology 20070501
Title: A comprehensive strategy for the subtyping of patients with Fanconi anaemia: conclusions from the Spanish Fanconi Anemia Research Network.
Journal: Journal of medical genetics 20070401
Title: Site specific N6-(2-hydroxy-3,4-epoxybut-1-yl)adenine oligodeoxynucleotide adducts of 1,2,3,4-diepoxybutane: synthesis and stability at physiological pH.
Journal: Chemical research in toxicology 20070401
Title: Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats.
Journal: Chemico-biological interactions 20070320
Title: Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites.
Journal: Chemico-biological interactions 20070320
Title: Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene.
Journal: Chemico-biological interactions 20070320
Title: Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells.
Journal: Chemico-biological interactions 20070320
Title: Structure of the 1,4-Bis(2'-deoxyadenosin-N(6)-yl)-2S,3S-butanediol intrastrand DNA cross-link arising from butadiene diepoxide in the human N-ras codon 61 sequence.
Journal: Chemical research in toxicology 20070201
Title: Structural elucidation of a novel DNA-DNA cross-link of 1,2,3,4-diepoxybutane.
Journal: Chemical research in toxicology 20070201
Title: Use of the arginine-specific butanedione/phenylboronic acid tag for analysis of peptides and protein digests using matrix-assisted laser desorption/ionization mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20070101
Title: Influence of polymorphisms in xenobiotic-metabolizing genes and DNA-repair genes on diepoxybutane-induced SCE frequency.
Journal: Environmental and molecular mutagenesis 20061201
Title: Cross-linking of the human DNA repair protein O6-alkylguanine DNA alkyltransferase to DNA in the presence of 1,2,3,4-diepoxybutane.
Journal: Chemical research in toxicology 20060501
Title: The role of foetal red blood cells in protecting cultured lymphocytes against diepoxybutane-induced chromosome breaks.
Journal: Mutation research 20060131
Title: The 5'-GNC site for DNA interstrand cross-linking is conserved for diepoxybutane stereoisomers.
Journal: Chemical research in toxicology 20060101
Title: Evidence for Escherichia coli polymerase II mutagenic bypass of intrastrand DNA crosslinks.
Journal: DNA repair 20051208
Title: Interstrand and intrastrand DNA-DNA cross-linking by 1,2,3,4-diepoxybutane: role of stereochemistry.
Journal: Journal of the American Chemical Society 20051019
Title: Chemical- and irradiation-induced mutants of indica rice IR64 for forward and reverse genetics.
Journal: Plant molecular biology 20050901
Title: Genotoxicity sensor response correlated with DNA nucleobase damage rates measured by LC-MS.
Journal: Molecular bioSystems 20050901
Title: Structure of the 1,4-bis(2'-deoxyadenosin-N6-yl)-2R,3R-butanediol cross-link arising from alkylation of the human N-ras codon 61 by butadiene diepoxide.
Journal: Biochemistry 20050802
Title: Reaction of 1,2,3,4-diepoxybutane with 2'-deoxyguanosine: initial products and their stabilities and decomposition patterns under physiological conditions.
Journal: Chemical research in toxicology 20050801
Title: Acute exposure of human lung cells to 1,3-butadiene diepoxide results in G1 and G2 cell cycle arrest.
Journal: Environmental and molecular mutagenesis 20050501
Title: Analysis of diepoxide-specific cyclic N-terminal globin adducts in mice and rats after inhalation exposure to 1,3-butadiene.
Journal: Cancer research 20041201
Title: Guanine-adenine DNA cross-linking by 1,2,3,4-diepoxybutane: potential basis for biological activity.
Journal: Chemical research in toxicology 20041201
Title: Hemoglobin adduct levels in rat and mouse treated with 1,2:3,4-diepoxybutane.
Journal: Chemical research in toxicology 20040601
Title: Characterization of the reaction products of 2'-deoxyguanosine and 1,2,3,4-diepoxybutane after acid hydrolysis: formation of novel guanine and pyrimidine adducts.
Journal: Chemical research in toxicology 20040401
Title: Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes.
Journal: Mutation research 20040314
Title: Diepoxybutane induces caspase and p53-mediated apoptosis in human lymphoblasts.
Journal: Toxicology and applied pharmacology 20040301
Title: Alpha-mercaptoketone formation during the maillard reaction of cysteine and [1-(13)C]ribose.
Journal: Journal of agricultural and food chemistry 20040225
Title: Structural characterization of the major DNA-DNA cross-link of 1,2,3,4-diepoxybutane.
Journal: Chemical research in toxicology 20040201
Title: Multiple endocrine neoplasia type 1 with unusual concomitance of various neoplastic disorders.
Journal: Endocrine journal 20040201
Title: DEB test for Fanconi anemia detection in patients with atypical phenotypes.
Journal: American journal of medical genetics. Part A 20040101
Title: Diepoxybutane.
Journal: Report on carcinogens : carcinogen profiles 20040101
Title: A definitive synthesis of D-myo-inositol 1,4,5,6-tetrakisphosphate and its enantiomer D-myo-inositol 3,4,5,6-tetrakisphosphate from a novel butane-2,3-diacetal-protected inositol.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20031215
Title: Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis.
Journal: Developmental cell 20031201
Title: Identification and characterization of a series of nucleoside adducts formed by the reaction of 2'-deoxyguanosine and 1,2,3,4-diepoxybutane under physiological conditions.
Journal: Chemical research in toxicology 20031201
Title: Odorants in breast milk.
Journal: Archives of pediatrics & adolescent medicine 20031001
Title: Diagnosis of fanconi anemia by diepoxybutane analysis.
Journal: Current protocols in human genetics 20030701
Title: Synthesis and characterization of peptides containing a cyclic Val adduct of diepoxybutane, a possible biomarker of human exposure to butadiene.
Journal: Chemical research in toxicology 20030501
Title: Role of haemoglobin in the protection of cultured lymphocytes against diepoxybutane (DEB), assessed by in vitro induced chromosome breakage.
Journal: Mutation research 20030420
Title: Differential diagnosis of Fanconi anemia by nitrogen mustard and diepoxybutane.
Journal: Annals of hematology 20030401
Title: A model of sensitivity: 1,3-butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene.
Journal: Environmental and molecular mutagenesis 20030101
Title: Mutations induced by 1,3-butadiene metabolites, butadiene diolepoxide, and 1,2,3,4-diepoxybutane at the Hprt locus in CHO-K1 cells.
Journal: Molecules and cells 20021231
Title: A novel diagnostic screen for defects in the Fanconi anemia pathway.
Journal: Blood 20021215
Title: Identification of the ribosomal proteins present in the vicinity of globin mRNA in the 40S initiation complex.
Journal: Journal of biochemistry 20021101
Title: The clastogenic response of the 1q12 heterochromatic region to DNA cross-linking agents is independent of the Fanconi anaemia pathway.
Journal: Carcinogenesis 20020801
Title: The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues.
Journal: The Journal of biological chemistry 20020712
Title: Sequence mapping of epoxide adducts in human hemoglobin with LC-tandem MS and the SALSA algorithm.
Journal: Chemical research in toxicology 20020601
Title: Redox-modulated xenobiotic action and ROS formation: a mirror or a window?
Journal: Human & experimental toxicology 20020201
Title: Ion trap mass spectrometry in the structural analysis of haemoglobin peptides modified by epichlorohydrin and diepoxybutane.
Journal: Rapid communications in mass spectrometry : RCM 20020101
Title: Uterine-ovarian biochemical and developmental interactions to the postimplantation treatment with a butadiene metabolite, diepoxybutane, in pregnant rats.
Journal: Journal of biochemical and molecular toxicology 20020101
Title: Opposite responses in two DNA repair capacity tests in lymphocytes of head and neck cancer patients.
Journal: Journal of applied genetics 20020101
Title: Diepoxybutane.
Journal: Report on carcinogens : carcinogen profiles 20020101
Title: The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange.
Journal: Carcinogenesis 20011201
Title: Diepoxybutane and mitomycin C toxicity is associated with the induction of oxidative DNA damage in sea urchin embryos.
Journal: Human & experimental toxicology 20011201
Title: Diepoxybutane and diepoxyoctane interstrand cross-linking of the 5S DNA nucleosomal core particle.
Journal: Biochemistry 20010904
Title: Functional residues on the enzyme active site of glyoxalase I from bovine brain.
Journal: Preparative biochemistry & biotechnology 20010801
Title: First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice.
Journal: Chemico-biological interactions 20010601
Title: Development of a preliminary physiologically based toxicokinetic (PBTK) model for 1,3-butadiene risk assessment.
Journal: Chemico-biological interactions 20010601
Title: Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms.
Journal: Chemico-biological interactions 20010601
Title: In vitro genotoxicity testing of (1-chloroethenyl)oxirane, a metabolite of beta-chloroprene.
Journal: Chemico-biological interactions 20010601
Title: Fanconi anemia. a statistical evaluation of cytogenetic results obtained from South African families.
Journal: Cancer genetics and cytogenetics 20010401
Title: Urinary butadiene diepoxide: a potential biomarker of blood diepoxide.
Journal: Toxicology 20010307
Title: Positional cloning of a novel Fanconi anemia gene, FANCD2.
Journal: Molecular cell 20010201
Title: A novel approach for identification and measurement of hemoglobin adducts with 1,2,3,4-diepoxybutane by liquid chromatography/electrospray ionisation mass spectrometry and matrix-assisted laser desorption/ionisation tandem mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20010101
Title: Electrospray ionization detection of inherently nonresponsive epoxides by peptide binding.
Journal: Rapid communications in mass spectrometry : RCM 20010101
Title: 1,3-butadiene: cancer, mutations, and adducts. Part I: Carcinogenicity of 1,2,3,4-diepoxybutane.
Journal: Research report (Health Effects Institute) 20000301
Title: Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium.
Journal: Carcinogenesis 19960101
