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Home Amines 565-20-8
565-20-8,MFCD00672496
Catalog No.:AA00EEGN

565-20-8 | N-MONOACETYL-4,4'-DIAMINODIPHENYL SULFONE

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$53.00   $37.00
- +
5mg
≥95%
in stock  
$192.00   $134.00
- +
10mg
≥95%
in stock  
$330.00   $231.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EEGN
Chemical Name:
N-MONOACETYL-4,4'-DIAMINODIPHENYL SULFONE
CAS Number:
565-20-8
Molecular Formula:
C14H14N2O3S
Molecular Weight:
290.3376
MDL Number:
MFCD00672496
SMILES:
CC(=O)Nc1ccc(cc1)S(=O)(=O)c1ccc(cc1)N
NSC Number:
27184
Properties
Properties
 
Form:
Solid  
MP:
>218°C (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
428  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
0.9  

Downstream Synthesis Route

[1]JournaloftheAmericanChemicalSociety,1941,vol.63,p.1930,1931

[2]JournaloftheChineseChemicalSociety(Peking),1947,vol.15,p.68,71    Chem.Abstr.,1948,p.723

[3]Arzneimittel-Forschung/DrugResearch,1989,vol.39,p.1081-1084

[4]JournaloftheChineseChemicalSociety(Peking),1947,vol.15,p.68,71    Chem.Abstr.,1948,p.723

[5]Patent:WO2016/16321,2016,A1.Locationinpatent:Page/Pagecolumn11

[6]Patent:DE740445,1937,    DRP/DRBPOrg.Chem.,

[1]Patent:US2020/123130,2020,A1.Locationinpatent:Paragraph0124

[2]JournaloftheAmericanChemicalSociety,1943,vol.65,p.2375

[1]Raizissetal.[JournaloftheAmericanChemicalSociety,1938,vol.61,p.2763]

[2]Miura[YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1942,vol.62,p.224,225][Chem.Abstr.,1950,p.10161]

Literature

Title: Acute dapsone overdose: the effects of continuous veno-venous haemofiltration on the elimination of dapsone.

Journal: Anaesthesia and intensive care 20111101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Folate-synthesizing enzyme system as target for development of inhibitors and inhibitor combinations against Candida albicans-synthesis and biological activity of new 2,4-diaminopyrimidines and 4'-substituted 4-aminodiphenyl sulfones.

Journal: Journal of medicinal chemistry 20040101

Title: Effects of H(2)-receptor antagonists on dapsone-induced methaemoglobinaemia in rats.

Journal: Pharmacological research 20020401

Title: Immunohematotoxicity studies with combinations of dapsone and zidovudine.

Journal: International immunopharmacology 20011101

Title: Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase.

Journal: The Journal of clinical investigation 19900201

Title: Role of dapsone hydroxylamine in dapsone-induced hemolytic anemia.

Journal: The Journal of pharmacology and experimental therapeutics 19880101

Title: Hemolytic anemia induced by dapsone transmitted through breast milk.

Journal: Annals of internal medicine 19820401

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SDS
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