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56985-40-1,MFCD00135238
Catalog No.:AA00E9L4

56985-40-1 | U-46619

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Purity
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1mg
≥98%
in stock  
$139.00   $97.00
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5mg
≥98%
in stock  
$625.00   $437.00
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10mg
≥98%
in stock  
$1,040.00   $728.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00E9L4
Chemical Name:
U-46619
CAS Number:
56985-40-1
Molecular Formula:
C21H34O4
Molecular Weight:
350.4923
MDL Number:
MFCD00135238
SMILES:
CCCCC[C@@H](/C=C/[C@H]1[C@@H]2OC[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2)O
Properties
Computed Properties
 
Complexity:
457  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  
XLogP3:
3.9  

Literature

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Title: Vasodilation and hypotension of CZ454, an analogue of lacidipine through inhibiting extracellular calcium influx.

Journal: Arzneimittel-Forschung 20120901

Title: Role of PKCα-p(38)MAPK-G(i)α axis in NADPH oxidase derived O(2)(·-)-mediated activation of cPLA(2) under U46619 stimulation in pulmonary artery smooth muscle cells.

Journal: Archives of biochemistry and biophysics 20120715

Title: Disruption of TRPV1-mediated coupling of coronary blood flow to cardiac metabolism in diabetic mice: role of nitric oxide and BK channels.

Journal: American journal of physiology. Heart and circulatory physiology 20120715

Title: Multiscale prediction of patient-specific platelet function under flow.

Journal: Blood 20120705

Title: The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat.

Journal: Canadian journal of physiology and pharmacology 20120701

Title: Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery.

Journal: American journal of physiology. Heart and circulatory physiology 20120615

Title: Pre-contraction with the thromboxane-mimetic U46619 enhances P2X receptor-mediated contractions in isolated porcine splenic artery.

Journal: Purinergic signalling 20120601

Title: Peroxisome proliferator-activated receptor-γ protects against vascular aging.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120515

Title: NADPH oxidase 4 mediates upregulation of type 4 phosphodiesterases in human endothelial cells.

Journal: Journal of cellular physiology 20120501

Title: Activation of thromboxane receptor modulates interleukin-1β-induced monocyte adhesion--a novel role of Nox1.

Journal: Free radical biology & medicine 20120501

Title: Cytochrome P-450 2C9 exerts a vasoconstrictor influence on coronary resistance vessels in swine at rest and during exercise.

Journal: American journal of physiology. Heart and circulatory physiology 20120415

Title: The role of prostanoid receptors in mediating the effects of PGE3 on human platelet function.

Journal: Thrombosis and haemostasis 20120401

Title: 2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition.

Journal: Bioorganic & medicinal chemistry 20120401

Title: Possible involvement of S-nitrosylation of brain cyclooxygenase-1 in bombesin-induced central activation of adrenomedullary outflow in rats.

Journal: European journal of pharmacology 20120315

Title: Role for the guanine nucleotide exchange factor phosphatidylinositol-3,4,5-trisphosphate-dependent rac exchanger 1 in platelet secretion and aggregation.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120301

Title: Angiotensin II receptor antagonist reduces subsequent uterine arterial dysfunction in pregnant offspring of protein-restricted rat dams.

Journal: The journal of obstetrics and gynaecology research 20120301

Title: Involvement of phosphatidylcholine-specific phospholipase C in thromboxane A₂ receptor-mediated extracellular Ca²⁺ influx in rat aorta.

Journal: European journal of pharmacology 20120227

Title: Thromboxane A(2) receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment.

Journal: Toxicology and applied pharmacology 20120215

Title: Antiserotonergic properties of terguride in blood vessels, platelets, and valvular interstitial cells.

Journal: The Journal of pharmacology and experimental therapeutics 20120201

Title: Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries.

Journal: Experimental physiology 20120201

Title: Thromboxane-induced actin polymerization in hypoxic pulmonary artery is independent of Rho.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120101

Title: Allergic inflammation induces a persistent mechanistic switch in thromboxane-mediated airway constriction in the mouse.

Journal: American journal of physiology. Lung cellular and molecular physiology 20120101

Title: Evidence for active control of perfusion within lung microvessels.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120101

Title: The GNB3 C825T polymorphism influences platelet aggregation in human whole blood.

Journal: Pharmacogenetics and genomics 20120101

Title: Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of Chagas disease, binds to TXA(2) but does not interact with glycoprotein PVI.

Journal: Thrombosis and haemostasis 20120101

Title: Site-directed mutations and the polymorphic variant Ala160Thr in the human thromboxane receptor uncover a structural role for transmembrane helix 4.

Journal: PloS one 20120101

Title: Impaired myogenic tone in isolated cerebral and coronary resistance arteries from the goto-kakizaki rat model of type 2 diabetes.

Journal: Journal of vascular research 20120101

Title: Natural product extract of Dicksonia sellowiana induces endothelium-dependent relaxations by a redox-sensitive Src- and Akt-dependent activation of eNOS in porcine coronary arteries.

Journal: Journal of vascular research 20120101

Title: Smooth muscle myosin inhibition: a novel therapeutic approach for pulmonary hypertension.

Journal: PloS one 20120101

Title: BF066, a novel dual target antiplatelet agent without significant bleeding.

Journal: PloS one 20120101

Title: Effect of antithrombin III on glycoprotein Ib/IX/V activation in human platelets: suppression of thromboxane A2 generation.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120101

Title: Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120101

Title: Prostanoid receptors involved in regulation of the beating rate of neonatal rat cardiomyocytes.

Journal: PloS one 20120101

Title: Developmental changes in mesenteric artery reactivity in embryonic and newly hatched chicks.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20111201

Title: Thromboxane and isoprostane share the same prostanoid receptors to increase human placental tone.

Journal: Placenta 20111201

Title: Insulin-stimulated L-arginine transport requires SLC7A1 gene expression and is associated with human umbilical vein relaxation.

Journal: Journal of cellular physiology 20111101

Title: Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries.

Journal: Clinical science (London, England : 1979) 20111101

Title: Improved bioavailability of epoxyeicosatrienoic acids reduces TP-receptor agonist-induced tension in human bronchi.

Journal: American journal of physiology. Lung cellular and molecular physiology 20111101

Title: Wnt5a potentiates U46619-induced platelet aggregation via the PI3K/Akt pathway.

Journal: Molecules and cells 20111031

Title: Nitric oxide-mediated relaxation to lactate of coronary circulation in the isolated perfused rat heart.

Journal: Journal of cardiovascular pharmacology 20111001

Title: KV7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fundus.

Journal: Pharmacological research 20111001

Title: NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues.

Journal: American journal of physiology. Lung cellular and molecular physiology 20111001

Title: 19,20-EpDPE, a bioactive CYP450 metabolite of DHA monoacyglyceride, decreases Ca²⁺ sensitivity in human pulmonary arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20111001

Title: Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20111001

Title: WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, Gαq and phospholipase Cβ in a signalling complex.

Journal: Journal of cell science 20111001

Title: Role of the AT2 receptor in modulating the angiotensin II contractile response of the uterine artery at mid-gestation.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20110901

Title: Preserved arterial vasodilatation via endothelial protease-activated receptor-2 in obese type 2 diabetic mice.

Journal: British journal of pharmacology 20110901

Title: Effects of glutathione-depleting drug buthionine sulfoximine and aging on activity of endothelium-derived relaxing and contracting factors in carotid artery of Sprague-Dawley rats.

Journal: Journal of cardiovascular pharmacology 20110901

Title: Honokiol attenuates vascular contraction through the inhibition of the RhoA/Rho-kinase signalling pathway in rat aortic rings.

Journal: The Journal of pharmacy and pharmacology 20110901

Title: Thromboxane-induced contractile response of human coronary arterioles is diminished after cardioplegic arrest.

Journal: The Annals of thoracic surgery 20110901

Title: The role of PGE(2) in human atherosclerotic plaque on platelet EP(3) and EP(4) receptor activation and platelet function in whole blood.

Journal: Journal of thrombosis and thrombolysis 20110801

Title: Contractile effects of 15-E2t-isoprostane and 15-F2t-isoprostane on chicken embryo ductus arteriosus.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110801

Title: Expansion of the human adipose-derived stromal vascular cell fraction yields a population of smooth muscle-like cells with markedly distinct phenotypic and functional properties relative to mesenchymal stem cells.

Journal: Tissue engineering. Part C, Methods 20110801

Title: Methodology and pharmacological analysis of effects of uterotonic compounds in human myometrium in vitro.

Journal: American journal of obstetrics and gynecology 20110801

Title: Cyclosporine A, FK506, and NIM811 ameliorate prolonged CBF reduction and impaired neurovascular coupling after cortical spreading depression.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110701

Title: Ceramide inhibits Kv currents and contributes to TP-receptor-induced vasoconstriction in rat and human pulmonary arteries.

Journal: American journal of physiology. Cell physiology 20110701

Title: Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart.

Journal: European journal of pharmacology 20110625

Title: Glucosamine increases vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aorta.

Journal: BMB reports 20110601

Title: Reduced endothelial dependent vasodilation in vessels from TLR4(-/-) mice is associated with increased superoxide generation.

Journal: Biochemical and biophysical research communications 20110520

Title: Bleeding tendency and impaired platelet function in a patient carrying a heterozygous mutation in the thromboxane A2 receptor.

Journal: Journal of thrombosis and haemostasis : JTH 20110501

Title: Retina evokes biphasic relaxations in retinal artery unrelated to endothelium, K(V), K(ATP), K(Ca) channels and methyl palmitate.

Journal: Microvascular research 20110501

Title: Interaction of angio-associated migratory cell protein with the TPα and TPβ isoforms of the human thromboxane A₂ receptor.

Journal: Cellular signalling 20110401

Title: The effects of oxidation products of arachidonic acid and n3 fatty acids on vascular and platelet function.

Journal: Free radical research 20110401

Title: Release of sphingosine-1-phosphate from human platelets is dependent on thromboxane formation.

Journal: Journal of thrombosis and haemostasis : JTH 20110401

Title: Secretoneurin facilitates endothelium-dependent relaxations in porcine coronary arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20110401

Title: Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery.

Journal: British journal of pharmacology 20110401

Title: BM-573 inhibits the development of early atherosclerotic lesions in Apo E deficient mice by blocking TP receptors and thromboxane synthase.

Journal: Prostaglandins & other lipid mediators 20110401

Title: Divergence between arterial perfusion and fatigue resistance in skeletal muscle in the metabolic syndrome.

Journal: Experimental physiology 20110301

Title: In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation.

Journal: Journal of thrombosis and haemostasis : JTH 20110301

Title: Pulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.

Journal: American journal of physiology. Heart and circulatory physiology 20110301

Title: T-type voltage-gated calcium channels regulate the tone of mouse efferent arterioles.

Journal: Kidney international 20110201

Title: Selective enhancement of contractions to α1-adrenergic receptor activation in the aorta of mice with sickle cell disease.

Journal: Journal of cardiovascular pharmacology 20110201

Title: Coronary vasoconstrictor effect of ghrelin is not mediated by growth hormone secretagogue receptor 1a type in dogs.

Journal: Peptides 20110201

Title: Enhanced airway smooth muscle cell thromboxane receptor signaling via activation of JNK MAPK and extracellular calcium influx.

Journal: European journal of pharmacology 20110115

Title: Thromboxane A2 induces contraction of human prostate smooth muscle by Rho kinase- and calmodulin-dependent mechanisms.

Journal: European journal of pharmacology 20110115

Title: 4-Methylnitrosamino-1-3-pyridyl-1-butanone (NNK) promotes lung cancer cell survival by stimulating thromboxane A2 and its receptor.

Journal: Oncogene 20110106

Title: Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways.

Journal: Cardiovascular research 20110101

Title: Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101

Title: Activation of NAD(P)H oxidases by thromboxane A2 receptor uncouples endothelial nitric oxide synthase.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110101

Title: Effects of gomisin A on vascular contraction in rat aortic rings.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110101

Title: Inhibitory effects of resveratrol on platelet activation induced by thromboxane a(2) receptor agonist in human platelets.

Journal: The American journal of Chinese medicine 20110101

Title: Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6.

Journal: Respiratory research 20110101

Title: Towards the maturation and characterization of smooth muscle cells derived from human embryonic stem cells.

Journal: PloS one 20110101

Title: Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse.

Journal: PloS one 20110101

Title: Effects of pioglitazone and rosiglitazone on vascular function of mesenteric resistance arteries in rat genetic hypertension.

Journal: Pharmacology 20110101

Title: [Ligand recognition mechanism of lipocalin-type prostaglandin D synthase].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

Title: Vasorelaxation, induced by Dictyota pulchella (Dictyotaceae), a brown alga, is mediated via inhibition of calcium influx in rats.

Journal: Marine drugs 20110101

Title: Glybenclamide: an antidiabetic with in vivo antithrombotic activity.

Journal: European journal of pharmacology 20101215

Title: Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20101201

Title: Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20101201

Title: Effect of amlodipine in human internal mammary artery and clinical implications.

Journal: The Annals of thoracic surgery 20101201

Title: Gathering of aging and estrogen withdrawal in vascular dysfunction of senescent accelerated mice.

Journal: Experimental gerontology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: The function and three-dimensional structure of a thromboxane A2/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.

Journal: PLoS biology 20101101

Title: Effect of blower-mister devices on vasoreactivity of coronary artery bypass grafts.

Journal: The Journal of thoracic and cardiovascular surgery 20101001

Title: Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation.

Journal: Thrombosis and haemostasis 20101001

Title: TRA-418, a thromboxane A2 receptor antagonist and prostacyclin receptor agonist, inhibits platelet-leukocyte interaction in human whole blood.

Journal: Thrombosis and haemostasis 20101001

Title: M₃muscarinic receptors mediate acetylcholine-induced pulmonary vasodilation in pulmonary hypertension.

Journal: Bioscience trends 20101001

Title: Interspecies differences and extracellular calcium dependence in the vasorelaxing effect of cromakalim in isolated human, porcine, and canine coronary arteries.

Journal: Journal of cardiovascular pharmacology and therapeutics 20100901

Title: Human thoracic duct in vitro: diameter-tension properties, spontaneous and evoked contractile activity.

Journal: American journal of physiology. Heart and circulatory physiology 20100901

Title: Hypoxia enhances the relaxing influence of perivascular adipose tissue in isolated mice aorta.

Journal: European journal of pharmacology 20100901

Title: Structural and functional analysis of the C-terminus of Galphaq in complex with the human thromboxane A2 receptor provides evidence of constitutive activity.

Journal: Biochemistry 20100803

Title: Effects of 3',4'-dihydroxyflavonol on vascular contractions of rat aortic rings.

Journal: Clinical and experimental pharmacology & physiology 20100801

Title: The mechanism by which RhoA regulates vascular reactivity after hemorrhagic shock in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20100801

Title: Development of a high-throughput ELISA assay for platelet function testing using platelet-rich plasma or whole blood.

Journal: Thrombosis and haemostasis 20100801

Title: The modulation of vascular ATP-sensitive K+ channel function via the phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine.

Journal: The Journal of pharmacology and experimental therapeutics 20100801

Title: Thromboxane A(2) increases endothelial permeability through upregulation of interleukin-8.

Journal: Biochemical and biophysical research communications 20100702

Title: Voltage-gated calcium channels are involved in the regulation of calcium oscillations in vascular smooth muscle cells from isolated porcine retinal arterioles.

Journal: Experimental eye research 20100701

Title: Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery.

Journal: American journal of physiology. Lung cellular and molecular physiology 20100701

Title: Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli.

Journal: Nature biotechnology 20100701

Title: Inhibitory activity of ginsenosides isolated from processed ginseng on platelet aggregation.

Journal: Die Pharmazie 20100701

Title: Response of chicken ductus arteriosus to hypercarbic and normocarbic acidosis.

Journal: Neonatology 20100601

Title: Thromboxane prostanoid receptor stimulation induces shedding of the transmembrane chemokine CX3CL1 yet enhances CX3CL1-dependent leukocyte adhesion.

Journal: American journal of physiology. Cell physiology 20100601

Title: Role for tyrosine kinases in contraction of rat penile small arteries.

Journal: The journal of sexual medicine 20100601

Title: The EP3-agonist sulprostone, but not prostaglandin E2 potentiates platelet aggregation in human blood.

Journal: Thrombosis and haemostasis 20100601

Title: Functional evidence for oxygen-sensitive voltage-gated potassium channels in human placental vasculature.

Journal: Placenta 20100601

Title: Effects of sex and estrogen on chicken ductus arteriosus reactivity.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100501

Title: Lysosome-dependent Ca(2+) release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts.

Journal: American journal of physiology. Cell physiology 20100501

Title: Thromboxane A(2) promotes soluble CD40 ligand release from human platelets.

Journal: Atherosclerosis 20100401

Title: Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase.

Journal: Shock (Augusta, Ga.) 20100401

Title: Presynaptic BK type Ca(2+)-activated K(+) channels are involved in prostanoid TP receptor-mediated inhibition of noradrenaline release from the rat gastric sympathetic nerves.

Journal: European journal of pharmacology 20100310

Title: Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

Title: Acetylsalicylic acid enhances purinergic receptor-mediated outward currents in rat megakaryocytes.

Journal: American journal of physiology. Cell physiology 20100301

Title: Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension.

Journal: Circulation. Cardiovascular imaging 20100301

Title: Biomechanics and vasoreactivity of female intramural coronaries in angiotensin II induced hypertension.

Journal: Acta physiologica Hungarica 20100301

Title: The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase.

Journal: Archives of pharmacal research 20100301

Title: Subarachnoid hemorrhage induces enhanced expression of thromboxane A2 receptors in rat cerebral arteries.

Journal: Brain research 20100226

Title: Continuous infusion of 17-hydroxyprogesterone caproate into either the fetoplacental or intervillous circulation of a placental cotyledon attenuates vasoconstriction of the fetoplacental arteries by thromboxane mimetic U46619.

Journal: American journal of obstetrics and gynecology 20100201

Title: Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery.

Journal: British journal of pharmacology 20100201

Title: Repurposing an old drug for a new use: glybenclamide exerts antiplatelet activity by interacting with the thromboxane A(2) receptor.

Journal: Acta pharmacologica Sinica 20100201

Title: A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis.

Journal: Blood 20100114

Title: Involvement of aquaporin in thromboxane A2 receptor-mediated, G 12/13/RhoA/NHE-sensitive cell swelling in 1321N1 human astrocytoma cells.

Journal: Cellular signalling 20100101

Title: Bradykinin and thromboxane A2 reciprocally interact to synergistically stimulate cardiac spinal afferents during myocardial ischemia.

Journal: American journal of physiology. Heart and circulatory physiology 20100101

Title: Brain apoptosis and carotid artery reactivity in fetal asphyctic preconditioning.

Journal: Frontiers in bioscience (Scholar edition) 20100101

Title: Natriuretic and renoprotective effect of chronic oral neutral endopeptidase inhibition in acute renal failure.

Journal: Renal failure 20100101

Title: Effects of rolipram on U46619-induced contraction and cyclic nucleotide content in the porcine coronary artery.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20100101

Title: The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function.

Journal: Platelets 20100101

Title: A novel system for the investigation of microvascular dysfunction including vascular permeability and flow-mediated dilatation in pressurised human arteries.

Journal: Journal of pharmacological and toxicological methods 20100101

Title: Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension.

Journal: Journal of cardiothoracic surgery 20100101

Title: Cyclic nucleotide-gated channels contribute to thromboxane A2-induced contraction of rat small mesenteric arteries.

Journal: PloS one 20100101

Title: Hypersensitivity to thromboxane receptor mediated cerebral vasomotion and CBF oscillations during acute NO-deficiency in rats.

Journal: PloS one 20100101

Title: Thromboxane A2 receptor-mediated epidermal growth factor receptor transactivation: involvement of PKC-delta and PKC-epsilon in the shedding of epidermal growth factor receptor ligands.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091208

Title: Preserved pulmonary vasodilative properties of aerosolized brain natriuretic peptide.

Journal: Pulmonary pharmacology & therapeutics 20091201

Title: Inhibition of thromboxane A2-induced arrhythmias and intracellular calcium changes in cardiac myocytes by blockade of the inositol trisphosphate pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20091201

Title: Comparison of the relative activities of inducing platelet apoptosis stimulated by various platelet-activating agents.

Journal: Platelets 20091201

Title: Direct vasodilative effect of FK506 on porcine mesenteric artery in small bowel transplantation.

Journal: Journal of pediatric surgery 20091201

Title: The arachidonic acid effect on platelet nitric oxide level.

Journal: Biochimica et biophysica acta 20091101

Title: Effects of endothelin-1 on the relaxation of rat coronary arteries.

Journal: Journal of cardiovascular pharmacology 20091101

Title: Impaired function of coronary BK(Ca) channels in metabolic syndrome.

Journal: American journal of physiology. Heart and circulatory physiology 20091101

Title: Functional characterization of contractions to tegaserod in human isolated proximal and distal coronary arteries.

Journal: European journal of pharmacology 20091001

Title: Intermolecular cross-talk between the prostaglandin E2 receptor (EP)3 of subtype and thromboxane A(2) receptor signalling in human erythroleukaemic cells.

Journal: British journal of pharmacology 20091001

Title: Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats.

Journal: Translational research : the journal of laboratory and clinical medicine 20091001

Title: [Regulation of the expression of inducible nitric oxide synthase by prostanoids].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091001

Title: Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists.

Journal: Thrombosis and haemostasis 20091001

Title: Genetic evidence for a predominant role of PI3Kbeta catalytic activity in ITAM- and integrin-mediated signaling in platelets.

Journal: Blood 20090903

Title: Ca2+- and thromboxane-dependent distribution of MaxiK channels in cultured astrocytes: from microtubules to the plasma membrane.

Journal: Glia 20090901

Title: Impairment of coronary endothelial cell ET(B) receptor function after short-term inhalation exposure to whole diesel emissions.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090901

Title: Platelet antiaggregating activity of ginsenosides isolated from processed ginseng.

Journal: Die Pharmazie 20090901

Title: Thromboxane prostanoid receptor activation impairs endothelial nitric oxide-dependent vasorelaxations: the role of Rho kinase.

Journal: Biochemical pharmacology 20090815

Title: Role of calcium-activated potassium channels with small conductance in bradykinin-induced vasodilation of porcine retinal arterioles.

Journal: Investigative ophthalmology & visual science 20090801

Title: Beneficial effect of propofol on arterial adenosine triphosphate-sensitive K+ channel function impaired by thromboxane.

Journal: Anesthesiology 20090801

Title: Acute and chronic modulation of placental chorionic plate artery reactivity by reactive oxygen species.

Journal: Free radical biology & medicine 20090715

Title: Role of protein kinase C in NADPH oxidase derived O2*(-)-mediated regulation of KV-LVOCC axis under U46619 induced increase in [Ca2+]i in pulmonary smooth muscle cells.

Journal: Archives of biochemistry and biophysics 20090715

Title: The ischemic metabolite lysophosphatidylcholine increases rat coronary arterial tone by endothelium-dependent mechanisms.

Journal: Journal of molecular and cellular cardiology 20090701

Title: Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling.

Journal: The Journal of biological chemistry 20090619

Title: Thromboxane and isoprostanes as inflammatory and vasoactive mediators in black walnut heartwood extract induced equine laminitis.

Journal: Veterinary immunology and immunopathology 20090615

Title: Time-dependent vascular actions of cannabidiol in the rat aorta.

Journal: European journal of pharmacology 20090610

Title: Effects of centrally administered prostaglandin E(3) and thromboxane A(3) on plasma noradrenaline and adrenaline in rats: comparison with prostaglandin E(2) and thromboxane A(2).

Journal: European journal of pharmacology 20090602

Title: Mechanisms of U46619-induced contraction of rat pulmonary arteries in the presence and absence of the endothelium.

Journal: British journal of pharmacology 20090601

Title: Thromboxane A2-induced signal transduction is negatively regulated by KIAA1005 that directly interacts with thromboxane A2 receptor.

Journal: Prostaglandins & other lipid mediators 20090601

Title: Comparison of 3 methods to induce acute pulmonary hypertension in pigs.

Journal: Comparative medicine 20090601

Title: Inhibitory effects of Atractylodis lanceae rhizoma and Poria on collagen- or thromboxane A2-induced aggregation in rabbit platelets.

Journal: Biological & pharmaceutical bulletin 20090501

Title: Two different mechanisms for modulation of bronchoconstriction in guinea-pigs by cyclooxygenase metabolites.

Journal: Prostaglandins & other lipid mediators 20090401

Title: Diagnostic utility of light transmission platelet aggregometry: results from a prospective study of individuals referred for bleeding disorder assessments.

Journal: Journal of thrombosis and haemostasis : JTH 20090401

Title: Peroxide generation by p47phox-Src activation of Nox2 has a key role in protein kinase C-induced arterial smooth muscle contraction.

Journal: American journal of physiology. Heart and circulatory physiology 20090401

Title: The effect of long-term hypoxia on tension and intracellular calcium responses following stimulation of the thromboxane A(2) receptor in the left anterior descending coronary artery of fetal sheep.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20090401

Title: Synergistic interaction between the Ligusticum chuanxiong constituent butylidenephthalide and the nitric oxide donor sodium nitroprusside in relaxing rat isolated aorta.

Journal: Journal of ethnopharmacology 20090318

Title: Mechanistic basis of differential conduction in skeletal muscle arteries.

Journal: The Journal of physiology 20090315

Title: Thromboxane A2-induced bi-directional regulation of cerebral arterial tone.

Journal: The Journal of biological chemistry 20090306

Title: Rac1 is essential for phospholipase C-gamma2 activation in platelets.

Journal: Pflugers Archiv : European journal of physiology 20090301

Title: Augmentation of U46619 induced human platelet aggregation by aspirin.

Journal: Platelets 20090301

Title: Coronary response to diadenosine pentaphosphate after ischaemia-reperfusion in the isolated rat heart.

Journal: Cardiovascular research 20090201

Title: Pulmonary vasodilator responses to sodium nitrite are mediated by an allopurinol-sensitive mechanism in the rat.

Journal: American journal of physiology. Heart and circulatory physiology 20090201

Title: Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090201

Title: Thromboxane A(2) modulates migration, proliferation, and differentiation of adipose tissue-derived mesenchymal stem cells.

Journal: Experimental & molecular medicine 20090131

Title: The vasodilating effect of acetazolamide and dorzolamide involves mechanisms other than carbonic anhydrase inhibition.

Journal: Investigative ophthalmology & visual science 20090101

Title: Normothermic and hypothermic models for studying the deleterious effects of hypoxia-reoxygenation on EDHF-mediated relaxation in isolated porcine coronary arteries.

Journal: Journal of pharmacological and toxicological methods 20090101

Title: Epoxyeicosatrienoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation.

Journal: The Journal of pharmacology and experimental therapeutics 20090101

Title: Thromboxane a(2) induces differentiation of human mesenchymal stem cells to smooth muscle-like cells.

Journal: Stem cells (Dayton, Ohio) 20090101

Title: An increased regional blood flow precedes mesenteric inflammation in rats treated by a phosphodiesterase 4 inhibitor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090101

Title: The Gq and G12 families of heterotrimeric G proteins report functional selectivity.

Journal: Molecular pharmacology 20090101

Title: Capsaicin blocks HIV protease inhibitor ritonavir-induced vascular dysfunction in porcine pulmonary arteries.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20090101

Title: Vascular effects of estrone and diethylstilbestrol in porcine coronary arteries.

Journal: Menopause (New York, N.Y.) 20090101

Title: Mechanism of the prostanoid TP receptor agonist U46619 for inducing emesis in the ferret.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20081201

Title: Altered responsiveness of small uterine arteries in women with idiopathic menorrhagia.

Journal: American journal of obstetrics and gynecology 20081201

Title: Effect of fetal anaemia on myocardial ischaemia-reperfusion injury and coronary vasoreactivity in adult sheep.

Journal: Acta physiologica (Oxford, England) 20081201

Title: Intra- and extrarenal arteries exhibit different profiles of contractile responses in high glucose conditions.

Journal: British journal of pharmacology 20081201

Title: Characterization of endothelial thromboxane receptors in rabbit aorta.

Journal: Prostaglandins & other lipid mediators 20081201

Title: Myocardial ischemia-mediated excitatory reflexes: a new function for thromboxane A2?

Journal: American journal of physiology. Heart and circulatory physiology 20081201

Title: Time-limited hyporesponsiveness to inhaled nitric oxide and pulmonary phosphodiesterase activity in endotoxemic rats.

Journal: The Journal of surgical research 20081101

Title: Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.

Journal: American journal of physiology. Lung cellular and molecular physiology 20081101

Title: COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081101

Title: The Gi-coupled P2Y12 receptor regulates diacylglycerol-mediated signaling in human platelets.

Journal: The Journal of biological chemistry 20081024

Title: Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis.

Journal: Circulation research 20081024

Title: p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction.

Journal: American journal of physiology. Heart and circulatory physiology 20081001

Title: Potassium channels sensitive to combination of charybdotoxin and apamin regulate the tone of diabetic isolated canine coronary arteries.

Journal: Acta physiologica (Oxford, England) 20080901

Title: Increased cyclooxygenase-2 and thromboxane synthase expression is implicated in diosgenin-induced megakaryocytic differentiation in human erythroleukemia cells.

Journal: Analytical biochemistry 20080901

Title: Hypertension and the absence of EDHF-mediated responses favour endothelium-dependent contractions in renal arteries of the rat.

Journal: British journal of pharmacology 20080901

Title: Comparison of the involvement of protein kinase C in agonist-induced contractions in mouse aorta and corpus cavernosum.

Journal: European journal of pharmacology 20080820

Title: Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass.

Journal: Surgery 20080801

Title: Endothelial nitric oxide attenuates Na+/Ca2+ exchanger-mediated vasoconstriction in rat aorta.

Journal: British journal of pharmacology 20080701

Title: Undiscovered role of endogenous thromboxane A2 in activation of cardiac sympathetic afferents during ischaemia.

Journal: The Journal of physiology 20080701

Title: Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.

Journal: Hypertension (Dallas, Tex. : 1979) 20080701

Title: Aldosterone induces endothelial dysfunction in resistance arteries from normotensive and hypertensive rats by increasing thromboxane A2 and prostacyclin.

Journal: British journal of pharmacology 20080701

Title: An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet counts.

Journal: Thrombosis and haemostasis 20080701

Title: Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica.

Journal: Archives of pharmacal research 20080701

Title: Characterization of prostanoid receptors present on adrenergic neurons innervating the porcine uterine longitudinal muscle.

Journal: Prostaglandins & other lipid mediators 20080601

Title: Tone-dependent vascular responses to astrocyte-derived signals.

Journal: American journal of physiology. Heart and circulatory physiology 20080601

Title: Short-term exposure to cigarette smoke induces endothelial dysfunction in small intrapulmonary arteries: analysis using guinea pig precision cut lung slices.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080501

Title: Sivelestat relaxes porcine coronary artery via inhibition of Ca2+ sensitization induced by a receptor agonist.

Journal: Journal of cardiovascular pharmacology 20080501

Title: The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.

Journal: Cardiovascular research 20080401

Title: Characterisation of tone oscillations in placental and myometrial arteries from normal pregnancies and those complicated by pre-eclampsia and growth restriction.

Journal: Placenta 20080401

Title: Loss of prostaglandin F2alpha, but not thromboxane, responsiveness in pregnant human myometrium during labour.

Journal: The Journal of endocrinology 20080401

Title: Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity.

Journal: European journal of pharmacology 20080331

Title: Na+/H+ exchange inhibition with cariporide prevents alterations of coronary endothelial function in streptozotocin-induced diabetes.

Journal: Molecular and cellular biochemistry 20080301

Title: Maturation of the contractile response of the Emu ductus arteriosus.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20080301

Title: Reciprocal regulation of platelet responses to P2Y and thromboxane receptor activation.

Journal: Journal of thrombosis and haemostasis : JTH 20080301

Title: Developmental changes in arginase expression and activity in the lung.

Journal: American journal of physiology. Lung cellular and molecular physiology 20080301

Title: The effect of maternal catecholamines on the caliber of gravid uterine microvessels.

Journal: Anesthesia and analgesia 20080301

Title: Thromboxane receptor activates the AMP-activated protein kinase in vascular smooth muscle cells via hydrogen peroxide.

Journal: Circulation research 20080215

Title: The relaxing effect of perivascular tissue on porcine retinal arterioles in vitro is mimicked by N-methyl-D-aspartate and is blocked by prostaglandin synthesis inhibition.

Journal: Acta ophthalmologica 20080201

Title: Intravital microscopy of the murine pulmonary microcirculation.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080201

Title: Effects of KP-496, a novel dual antagonist at the cysteinyl leukotriene receptor 1 and the thromboxane A(2) receptor, on airway obstruction in guinea pigs.

Journal: British journal of pharmacology 20080201

Title: Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin.

Journal: Biochemistry 20080115

Title: Contribution of prostaglandin D2 via prostanoid DP receptor to nasal hyperresponsiveness in guinea pigs repeatedly exposed to antigen.

Journal: European journal of pharmacology 20080114

Title: Altered TP receptor function in isolated, perfused kidneys of nondiabetic and diabetic ApoE-deficient mice.

Journal: American journal of physiology. Renal physiology 20080101

Title: Differential effects of chronic hypoxia and intermittent hypocapnic and eucapnic hypoxia on pulmonary vasoreactivity.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20080101

Title: Characterization of agonist-induced vasoconstriction in mouse pulmonary artery.

Journal: American journal of physiology. Heart and circulatory physiology 20080101

Title: Thromboxane A2 receptors in prostate carcinoma: expression and its role in regulating cell motility via small GTPase Rho.

Journal: Cancer research 20080101

Title: The effect of a mast cell degranulating agent on vascular resistance in the human placental vascular bed and on the tone of isolated placental vessels.

Journal: Reproductive sciences (Thousand Oaks, Calif.) 20080101

Title: Endothelin-1 potentiation of coronary artery contraction after ischemia-reperfusion.

Journal: Vascular pharmacology 20080101

Title: Effect of phospholipase C blockade on cerebral vasospasm.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20080101

Title: Selective arterial dilatation by glyceryl trinitrate is not associated with nitric oxide formation in vitro.

Journal: Journal of vascular research 20080101

Title: Acute inhibition of superoxide formation and Rac1 activation by nitric oxide and iloprost in human vascular smooth muscle cells in response to the thromboxane A2 analogue, U46619.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20080101

Title: Hindlimb unweighting induces changes in the RhoA-Rho-kinase pathway of the rat abdominal aorta.

Journal: Vascular pharmacology 20080101

Title: Exogenous hydrogen sulfide inhibits superoxide formation, NOX-1 expression and Rac1 activity in human vascular smooth muscle cells.

Journal: Journal of vascular research 20080101

Title: Hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy is unaltered by long-term oral L-arginine administration.

Journal: Vascular pharmacology 20080101

Title: Characterization of the non-adrenergic/non-cholinergic response to perivascular nerve stimulation in the double-perfused mesenteric bed of the mouse.

Journal: British journal of pharmacology 20071201

Title: Alteration of release and role of adenosine diphosphate and thromboxane A2 during collagen-induced aggregation of platelets from cattle with Chediak-Higashi syndrome.

Journal: American journal of veterinary research 20071201

Title: Enhanced platelet aggregation and activation under conditions of hypothermia.

Journal: Thrombosis and haemostasis 20071201

Title: Imperatorin induces vasodilatation possibly via inhibiting voltage dependent calcium channel and receptor-mediated Ca2+ influx and release.

Journal: European journal of pharmacology 20071114

Title: Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed.

Journal: British journal of pharmacology 20071101

Title: Purinergic 2X1 receptors mediate endothelial dependent vasodilation to ATP.

Journal: Molecular pharmacology 20071101

Title: Flavone inhibits vascular contraction by decreasing phosphorylation of the myosin phosphatase target subunit.

Journal: Clinical and experimental pharmacology & physiology 20071101

Title: Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619.

Journal: British journal of pharmacology 20071101

Title: Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: contribution of thromboxane A2.

Journal: Thrombosis and haemostasis 20071101

Title: Hydrogen peroxide mediates a transient vasorelaxation with tempol during oxidative stress.

Journal: American journal of physiology. Heart and circulatory physiology 20071001

Title: Effects of L-NAME on thromboxane A2-induced venoconstriction in isolated perfused livers from rat, guinea pig and mouse.

Journal: Vascular pharmacology 20071001

Title: Variable involvement of the perivascular retinal tissue in carbonic anhydrase inhibitor induced relaxation of porcine retinal arterioles in vitro.

Journal: Investigative ophthalmology & visual science 20071001

Title: Role of tyrosine phosphorylation in U46619-induced vasoconstriction of pulmonary vasculature and its modulation by genistein, daidzein, and equol.

Journal: Journal of cardiovascular pharmacology 20071001

Title: Piperlongumine, a constituent of Piper longum L., inhibits rabbit platelet aggregation as a thromboxane A(2) receptor antagonist.

Journal: European journal of pharmacology 20070910

Title: cGMP-dependent protein kinase in regulation of basal tone and in nitroglycerin- and nitric-oxide-induced relaxation in porcine coronary artery.

Journal: Pflugers Archiv : European journal of physiology 20070901

Title: Pulmonary hemodynamics in neonatal lambs resuscitated with 21%, 50%, and 100% oxygen.

Journal: Pediatric research 20070901

Title: Thromboxane A2 induces itch-associated responses through TP receptors in the skin in mice.

Journal: The Journal of investigative dermatology 20070801

Title: Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: Effect of recombinant aprotinin on postoperative blood loss and coronary vascular function in a canine model of cardiopulmonary bypass.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20070801

Title: Mechanisms of U46619- and 5-HT-induced contraction of bovine pulmonary arteries: role of chloride ions.

Journal: British journal of pharmacology 20070801

Title: BM-520, an original TXA2 modulator, inhibits the action of thromboxane A2 and 8-iso-prostaglandin F2alphain vitro and in vivo on human and rodent platelets, and aortic vascular smooth muscles from rodents.

Journal: Prostaglandins & other lipid mediators 20070801

Title: Pulmonary endothelium dependent vasodilation emerges after birth in mice.

Journal: European journal of pharmacology 20070719

Title: Comparison of relaxation responses to multiple vasodilators in TxA(2)-analog and endothelin-1-precontracted pulmonary arteries.

Journal: Acta anaesthesiologica Scandinavica 20070701

Title: Inhibitory effect of ethanol extract of Piper longum L. on rabbit platelet aggregation through antagonizing thromboxane A2 receptor.

Journal: Biological & pharmaceutical bulletin 20070701

Title: Inhaled amyl nitrite effectively reverses acute catastrophic thromboxane-mediated pulmonary hypertension in pigs.

Journal: Annals of cardiac anaesthesia 20070701

Title: Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding.

Journal: The Journal of pharmacology and experimental therapeutics 20070601

Title: Raised tone reveals purinergic-mediated responses to sympathetic nerve stimulation in the rat perfused mesenteric vascular bed.

Journal: European journal of pharmacology 20070601

Title: Homologous desensitization of signalling by the alpha (alpha) isoform of the human thromboxane A2 receptor: a specific role for nitric oxide signalling.

Journal: Biochimica et biophysica acta 20070601

Title: Distinct roles of estrogen receptors alpha and beta mediating acute vasodilation of epicardial coronary arteries.

Journal: Hypertension (Dallas, Tex. : 1979) 20070601

Title: Potentiation of adrenaline vasoconstrictor response by sub-threshold concentrations of U-46619 in human umbilical vein: involvement of smooth muscle prostanoid TP(alpha) receptor isoform.

Journal: European journal of pharmacology 20070521

Title: Tamoxifen and estrogen attenuate enhanced vascular reactivity induced by estrogen deficiency in rat carotid arteries.

Journal: Biochemical pharmacology 20070501

Title: RhoA prenylation inhibitor produces relaxation of tonic smooth muscle of internal anal sphincter.

Journal: The Journal of pharmacology and experimental therapeutics 20070501

Title: Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production.

Journal: Atherosclerosis 20070401

Title: Vasorelaxation induced by vascular endothelial growth factor in the human internal mammary artery and radial artery.

Journal: Vascular pharmacology 20070401

Title: Smooth muscle mediates circumferential conduction of hyperpolarization and relaxation to focal endothelial cell activation in large coronary arteries.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070401

Title: The inhibitory effect of rosiglitazone on agonist-induced or spontaneous regulation of contractility.

Journal: Archives of pharmacal research 20070401

Title: Evidence that a prostanoid produced by cyclo-oxygenase-2 enhances contractile responses of the porcine isolated coronary artery following exposure to lipopolysaccharide.

Journal: British journal of anaesthesia 20070301

Title: Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070301

Title: Redox-sensitive impairment of porcine coronary artery vasodilation by hypochlorite-modified LDL.

Journal: Atherosclerosis 20070201

Title: Hyposmotic challenge inhibits inward rectifying K+ channels in cerebral arterial smooth muscle cells.

Journal: American journal of physiology. Heart and circulatory physiology 20070201

Title: Intrauterine growth restriction delays cardiomyocyte maturation and alters coronary artery function in the fetal sheep.

Journal: The Journal of physiology 20070201

Title: Differential effects of nitric oxide synthase inhibitors on endothelium-dependent and nitrergic nerve-mediated vasodilatation in the bovine ciliary artery.

Journal: British journal of pharmacology 20070201

Title: Involvement of Na+-Ca2+ exchanger in cAMP-mediated relaxation in mice aorta: evaluation using transgenic mice.

Journal: British journal of pharmacology 20070201

Title: Contractile and relaxant properties of rat-isolated pulmonary veins related to localization and histology.

Journal: Fundamental & clinical pharmacology 20070201

Title: Regulation of human internal mammary and radial artery contraction by extracellular and intracellular calcium channels and cyclic adenosine 3', 5' monophosphate.

Journal: The Annals of thoracic surgery 20070201

Title: Platelet aggregability in patients with hypertension treated with angiotensin II type 1 receptor blockers.

Journal: Journal of atherosclerosis and thrombosis 20070201

Title: Endothelium-independent relaxation to raloxifene in porcine coronary artery.

Journal: European journal of pharmacology 20070126

Title: Prostaglandins mediate tonic contraction of the guinea pig and human gallbladder.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070101

Title: Ontogeny of chicken ductus arteriosus response to oxygen and vasoconstrictors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070101

Title: Distinct effects of z-335, a new thromboxane A2 receptor antagonist, on rabbit platelets and aortic smooth muscle.

Journal: Pharmacology 20070101

Title: Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs.

Journal: Respiratory research 20070101

Title: The role of cyclooxygenase in the feline pulmonary vascular bed.

Journal: American journal of therapeutics 20070101

Title: Differential effects of losartan and candesartan on vasoconstrictor responses in the rat.

Journal: Canadian journal of physiology and pharmacology 20070101

Title: Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery.

Journal: European journal of pharmacology 20061215

Title: Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.

Journal: Allergology international : official journal of the Japanese Society of Allergology 20061201

Title: Cordycepin (3'-deoxyadenosine) inhibits human platelet aggregation induced by U46619, a TXA2 analogue.

Journal: The Journal of pharmacy and pharmacology 20061201

Title: Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries.

Journal: Annals of the New York Academy of Sciences 20061201

Title: Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets.

Journal: The Biochemical journal 20061115

Title: Characterization of thromboxane A2 receptor signaling in developing rat oligodendrocytes: nuclear receptor localization and stimulation of myelin basic protein expression.

Journal: Journal of neuroscience research 20061115

Title: Activation of the central cholinergic system mediates the reversal of hypotension by centrally administrated U-46619, a thromboxane A2 analog, in hemorrhaged rats.

Journal: Brain research 20061106

Title: 20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: role of cyclooxygenase.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Rho-kinase-mediated regulation of receptor-agonist-stimulated smooth muscle contraction.

Journal: Pflugers Archiv : European journal of physiology 20061101

Title: Chronic estrogen treatment reduces vaso-constrictor responses in insulin resistant rats.

Journal: Canadian journal of physiology and pharmacology 20061101

Title: Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans.

Journal: Circulation 20061010

Title: Reactivity of human placental chorionic plate vessels from pregnancies complicated by intrauterine growth restriction (IUGR).

Journal: Biology of reproduction 20061001

Title: Effect of testosterone on ex vivo vascular reactivity in man.

Journal: Clinical science (London, England : 1979) 20061001

Title: Propofol and thiopental attenuate adenosine triphosphate-sensitive potassium channel relaxation in pulmonary veins.

Journal: American journal of physiology. Lung cellular and molecular physiology 20061001

Title: 17-Hydroxyprogesterone caproate reverses induced vasoconstriction of the fetoplacental arteries by the thromboxane mimetic U46619.

Journal: American journal of obstetrics and gynecology 20061001

Title: Antiplatelet and antithrombotic activities of Korean Red Ginseng.

Journal: Archives of pharmacal research 20061001

Title: Thromboxane A2 receptor-mediated G12/13-dependent glial morphological change.

Journal: European journal of pharmacology 20060918

Title: 8-Isoprostane-induced endothelin-1 production by infant rat pulmonary artery smooth muscle cells is mediated by Rho-kinase.

Journal: Free radical biology & medicine 20060915

Title: Role of PPAR-gamma on the pathogenesis and vascular changes in glycerol-induced acute renal failure.

Journal: Pharmacological research 20060901

Title: Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization.

Journal: Vascular pharmacology 20060901

Title: Different mechanisms between thromboxane A2- and leukotriene D4-induced nasal blockage in guinea pigs.

Journal: Prostaglandins & other lipid mediators 20060901

Title: Homologous desensitization of signalling by the beta (beta) isoform of the human thromboxane A2 receptor.

Journal: Biochimica et biophysica acta 20060901

Title: Do heterotrimeric G proteins redistribute upon G protein-coupled receptor stimulation in platelets?

Journal: Platelets 20060901

Title: Increased secretion of leukemia inhibitory factor by immature airway smooth muscle cells enhances intracellular signaling and airway contractility.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060801

Title: High-glucose-altered endothelial cell function involves both disruption of cell-to-cell connection and enhancement of force development.

Journal: The Journal of pharmacology and experimental therapeutics 20060801

Title: High-dose atorvastatin improves hypercholesterolemic coronary endothelial dysfunction without improving the angiogenic response.

Journal: Circulation 20060704

Title: Efficacy of different vasodilators on human umbilical arterial smooth muscle under normal and reduced oxygen conditions.

Journal: Early human development 20060701

Title: Kaempferol enhances endothelium-independent and dependent relaxation in the porcine coronary artery.

Journal: Molecular and cellular biochemistry 20060701

Title: Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11).

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701

Title: Identification and characterization of a collagen-induced platelet aggregation inhibitor, triplatin, from salivary glands of the assassin bug, Triatoma infestans.

Journal: The FEBS journal 20060701

Title: Effects of platelet-activating factor, thromboxane A2 and leukotriene D4 on isolated perfused rat liver.

Journal: Prostaglandins & other lipid mediators 20060701

Title: A new role for FcgammaRIIA in the potentiation of human platelet activation induced by weak stimulation.

Journal: Cellular signalling 20060601

Title: Intermedin/adrenomedullin-2 dilates the rat pulmonary vascular bed: dependence on CGRP receptors and nitric oxide release.

Journal: Peptides 20060601

Title: Selective cerebral vascular dysfunction in Mn-SOD-deficient mice.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060601

Title: Mechanisms of agonist-induced constriction in isolated human mesenteric arteries.

Journal: Vascular pharmacology 20060601

Title: Critical role of ADP interaction with P2Y12 receptor in the maintenance of alpha(IIb)beta3 activation: association with Rap1B activation.

Journal: Journal of thrombosis and haemostasis : JTH 20060601

Title: Thromboxane receptor stimulation suppresses guanylate cyclase-mediated relaxation of radial arteries.

Journal: The Annals of thoracic surgery 20060601

Title: Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20060601

Title: Superoxide auto-augments superoxide formation and upregulates gp91(phox) expression in porcine pulmonary artery endothelial cells: inhibition by iloprost.

Journal: European journal of pharmacology 20060524

Title: Mechanisms underlying the vasorelaxing effects of butylidenephthalide, an active constituent of Ligusticum chuanxiong, in rat isolated aorta.

Journal: European journal of pharmacology 20060510

Title: Intratracheal administration of sildenafil and surfactant alleviates the pulmonary hypertension in newborn piglets.

Journal: Resuscitation 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Effect of hypoxia-reoxygenation on endothelial function in porcine cardiac microveins.

Journal: The Annals of thoracic surgery 20060501

Title: A novel dual antagonist of thromboxane A2 and leukotriene D4 receptors: synthesis and structure-activity relationships of chloroquinolylvinyl derivatives.

Journal: Chemical & pharmaceutical bulletin 20060501

Title: Mass-dependent signaling between G protein coupled receptors.

Journal: Cellular signalling 20060401

Title: Thromboxane A2-induced arrhythmias in the anesthetized rabbit.

Journal: American journal of physiology. Heart and circulatory physiology 20060401

Title: Impact of mitochondria and NADPH oxidases on acute and sustained hypoxic pulmonary vasoconstriction.

Journal: American journal of respiratory cell and molecular biology 20060401

Title: Physiological significance of thromboxane A(2) receptor dimerization.

Journal: Journal of pharmacological sciences 20060401

Title: Different pathways for activation of extracellular signal-regulated kinase through thromboxane A2 receptor isoforms.

Journal: Biological & pharmaceutical bulletin 20060401

Title: Ascorbate elevates perfusion pressure in the bovine extraocular long posterior ciliary artery: role of endothelium-derived hyperpolarizing factor (EDHF).

Journal: European journal of pharmacology 20060318

Title: Treatment with phosphodiesterase inhibitors type III and V: milrinone and sildenafil is an effective combination during thromboxane-induced acute pulmonary hypertension.

Journal: British journal of anaesthesia 20060301

Title: Effect of the oestrous cycle, pregnancy and uterine region on the responsiveness of the isolated mouse uterus to prostaglandin F(2alpha) and the thromboxane mimetic U46619.

Journal: The Journal of endocrinology 20060301

Title: Distinct agonist responsibilities of the first and second branches of mouse mesenteric artery.

Journal: Journal of cardiovascular pharmacology 20060301

Title: Mechanisms of the prostaglandin F2alpha-induced rise in [Ca2+]i in rat intrapulmonary arteries.

Journal: The Journal of physiology 20060215

Title: Modulatory effect of interleukin-1beta on rat isolated basilar artery contraction.

Journal: European journal of pharmacology 20060215

Title: Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060201

Title: Selective right, but not left, coronary endothelial dysfunction precedes development of pulmonary hypertension and right heart hypertrophy in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20060201

Title: Hypoxia induces hypersensitivity and hyperreactivity to thromboxane receptor agonist in neonatal pulmonary arterial myocytes.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060201

Title: Dominant role for calpain in thromboxane-induced neuromicrovascular endothelial cytotoxicity.

Journal: The Journal of pharmacology and experimental therapeutics 20060201

Title: Endoscopic versus conventional radial artery harvest for coronary artery bypass grafting: functional and histologic assessment of the conduit.

Journal: The Journal of thoracic and cardiovascular surgery 20060201

Title: Platelet ADP response deteriorates in synthetic storage media.

Journal: Transfusion 20060201

Title: Neutrophil antimicrobial peptide alpha-defensin causes endothelial dysfunction in porcine coronary arteries.

Journal: Journal of vascular surgery 20060201

Title: Characterisation of CGRP receptors in human and porcine isolated coronary arteries: evidence for CGRP receptor heterogeneity.

Journal: European journal of pharmacology 20060113

Title: Oxygen tension and normalisation pressure modulate nifedipine-sensitive relaxation of human placental chorionic plate arteries.

Journal: Placenta 20060101

Title: Glibenclamide inhibits agonist-induced vasoconstriction of placental chorionic plate arteries.

Journal: Placenta 20060101

Title: Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20060101

Title: Metabolite ligands of estrogen receptor-beta reduce primate coronary hyperreactivity.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Role of pentose phosphate pathway-derived NADPH in hypoxic pulmonary vasoconstriction.

Journal: Pulmonary pharmacology & therapeutics 20060101

Title: Regulation of transplacental water transfer: the role of fetoplacental venous tone.

Journal: Placenta 20060101

Title: Comparative effects of tolazoline and nitroprusside on human isolated radial artery.

Journal: The Annals of thoracic surgery 20060101

Title: Vasoactive responses of U46619, PGF2alpha, latanoprost, and travoprost in isolated porcine ciliary arteries.

Journal: Investigative ophthalmology & visual science 20060101

Title: Inhibitory effect of erythropoietin on contractility of human chorionic plate vessels.

Journal: American journal of obstetrics and gynecology 20060101

Title: Intramural coronary artery constrictor reactivity to thromboxane is higher in male than in female rats.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060101

Title: Hypoxic vasoconstriction of partial muscular intra-acinar pulmonary arteries in murine precision cut lung slices.

Journal: Respiratory research 20060101

Title: Comparison of pharmacokinetics and vasodilatory effect of nebulized and infused iloprost in experimental pulmonary hypertension: rapid tolerance development.

Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20060101

Title: Effects of endothelin receptor blockade on hypervasoreactivity in streptozotocin-diabetic rats: vessel-specific involvement of thromboxane A2.

Journal: Canadian journal of physiology and pharmacology 20060101

Title: Regulation of cerebral microvascular endothelial cell cyclooxygenase-2 message and activity by blood derived vasoactive agents.

Journal: Brain research bulletin 20051230

Title: Nongenomic responses to 17beta-estradiol in male rat mesenteric arteries abolish intrinsic gender differences in vascular responses.

Journal: British journal of pharmacology 20051201

Title: Effects of BM-573, a thromboxane A2 modulator on systemic hemodynamics perturbations induced by U-46619 in the pig.

Journal: Prostaglandins & other lipid mediators 20051201

Title: CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.

Journal: European journal of pharmacology 20051107

Title: Oligomerization of the alpha and beta isoforms of the thromboxane A2 receptor: relevance to receptor signaling and endocytosis.

Journal: Cellular signalling 20051101

Title: Cellular mechanisms of thromboxane A2-mediated contraction in pulmonary veins.

Journal: American journal of physiology. Lung cellular and molecular physiology 20051101

Title: Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin.

Journal: British journal of pharmacology 20051101

Title: Gender-specific alteration of adrenergic responses in small femoral arteries from estrogen receptor-beta knockout mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20051101

Title: Involvement of brain thromboxane A in hypotension induced by haemorrhage in rats.

Journal: Clinical and experimental pharmacology & physiology 20051101

Title: Role of cytosolic phospholipase A2 in the enhancement of alpha2-adrenoceptor-mediated vasoconstriction by the thromboxane-mimetic U46619 in the porcine isolated ear artery: comparison with vasopressin-enhanced responses.

Journal: Biochemical pharmacology 20051015

Title: Dual actions of dephostatin on the nitric oxide/cGMP-signalling pathway in porcine iliac arteries.

Journal: European journal of pharmacology 20051003

Title: Estrogen potentiates vasopressin-induced contraction of female rat aorta by enhancing cyclooxygenase-2 and thromboxane function.

Journal: American journal of physiology. Heart and circulatory physiology 20051001

Title: 5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20051001

Title: Angiotensin-(1-7) enhances anti-aggregatory effects of the nitric oxide donor sodium nitroprusside.

Journal: Journal of cardiovascular pharmacology 20051001

Title: Insulin resistance does not impair contractile responses of cerebral arteries.

Journal: Life sciences 20050916

Title: Soy isoflavones improve endothelial function in spontaneously hypertensive rats in an estrogen-independent manner: role of nitric-oxide synthase, superoxide, and cyclooxygenase metabolites.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Thromboxane A2 promotes interleukin-6 biosynthesis mediated by an activation of cyclic AMP-response element-binding protein in 1321N1 human astrocytoma cells.

Journal: Molecular pharmacology 20050901

Title: Sildenafil citrate and sildenafil nitrate (NCX 911) are potent inhibitors of superoxide formation and gp91phox expression in porcine pulmonary artery endothelial cells.

Journal: British journal of pharmacology 20050901

Title: An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets.

Journal: Basic & clinical pharmacology & toxicology 20050901

Title: A novel in vitro endothelium-dependent vascular relaxant effect of Apocynum venetum leaf extract.

Journal: Clinical and experimental pharmacology & physiology 20050901

Title: Organ-cultured airway explants: a new model of airway hyperresponsiveness.

Journal: Experimental lung research 20050901

Title: Congenital erythropoietin over-expression causes 'anti-pulmonary hypertensive' structural and functional changes in mice, both in normoxia and hypoxia.

Journal: Thrombosis and haemostasis 20050901

Title: Molecular indices of apoptosis after intermittent blood and crystalloid cardioplegia.

Journal: Circulation 20050830

Title: Estrogen restores postischemic sensitivity to the thromboxane mimetic U46619 in rat pial artery.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050801

Title: Testosterone treatment increases thromboxane function in rat cerebral arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20050801

Title: RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells.

Journal: American journal of physiology. Cell physiology 20050801

Title: Thromboxane A2-induced contraction of rat caudal arterial smooth muscle involves activation of Ca2+ entry and Ca2+ sensitization: Rho-associated kinase-mediated phosphorylation of MYPT1 at Thr-855, but not Thr-697.

Journal: The Biochemical journal 20050801

Title: Angiotensin II dilates bovine adrenal cortical arterioles: role of endothelial nitric oxide.

Journal: Endocrinology 20050801

Title: Sildenafil inhibits the formation of superoxide and the expression of gp47 NAD[P]H oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells.

Journal: BJU international 20050801

Title: Thromboxane A2 up-regulates neutrophil elastase release in Syrian hamsters with trinitrobenzene sulfonic acid-induced colitis.

Journal: Journal of pharmacological sciences 20050801

Title: Raloxifene relaxes rat intrarenal arteries by inhibiting Ca2+ influx.

Journal: American journal of physiology. Renal physiology 20050701

Title: Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.

Journal: The Journal of biological chemistry 20050701

Title: The specific thromboxane receptor antagonist S18886: pharmacokinetic and pharmacodynamic studies.

Journal: Journal of thrombosis and haemostasis : JTH 20050701

Title: Comparison of the inhibitory effects of docosahexaenoic acid (DHA) on U46619- and phenylephrine-induced contractions in guinea-pig aorta.

Journal: Biological & pharmaceutical bulletin 20050701

Title: The involvement of central cholinergic system in the pressor effect of intracerebroventricularly injected U-46619, a thromboxane A2 analog, in conscious normotensive rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050701

Title: U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance.

Journal: American journal of physiology. Heart and circulatory physiology 20050601

Title: Effects of HIV protease inhibitor ritonavir on vasomotor function and endothelial nitric oxide synthase expression.

Journal: Journal of acquired immune deficiency syndromes (1999) 20050601

Title: Dual impact of a nitric oxide donor, GEA 3175, in human pulmonary smooth muscle.

Journal: European journal of pharmacology 20050523

Title: Inhibition of endogenous nitric oxide in the heart enhances matrix metalloproteinase-2 release.

Journal: British journal of pharmacology 20050501

Title: Sildenafil citrate (Viagra) enhances vasodilatation in fetal growth restriction.

Journal: The Journal of clinical endocrinology and metabolism 20050501

Title: Stimulation of cannabinoid (CB1) and prostanoid (EP2) receptors opens BKCa channels and relaxes ocular trabecular meshwork.

Journal: Experimental eye research 20050501

Title: Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries.

Journal: Journal of vascular surgery 20050501

Title: C-reactive protein does not relax vascular smooth muscle: effects mediated by sodium azide in commercially available preparations.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Effects of isoprostane on tubuloglomerular feedback: roles of TP receptors, NOS, and salt intake.

Journal: American journal of physiology. Renal physiology 20050401

Title: Thromboxane prostanoid receptor signals through Gi protein to rapidly activate extracellular signal-regulated kinase in human airways.

Journal: American journal of respiratory cell and molecular biology 20050401

Title: Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction.

Journal: Cardiovascular research 20050401

Title: Thromboxane A receptor-mediated cell proliferation, survival and gene expression in oligodendrocytes.

Journal: Journal of neurochemistry 20050401

Title: The isoprostane 8-iso-PGF2alpha suppresses monocyte adhesion to human microvascular endothelial cells via two independent mechanisms.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301

Title: Effect of ischemia duration and nitric oxide on coronary vasoconstriction after ischemia-reperfusion.

Journal: European journal of pharmacology 20050221

Title: The synthesis of 20-HETE in small porcine coronary arteries antagonizes EDHF-mediated relaxation.

Journal: Cardiovascular research 20050201

Title: The pore-forming subunit of the K(ATP) channel is an important molecular target for LPS-induced vascular hyporeactivity in vitro.

Journal: British journal of pharmacology 20050201

Title: Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility.

Journal: Experimental eye research 20050201

Title: Extracellular signal-regulated kinase1/2 in contraction of vascular smooth muscle.

Journal: Life sciences 20050107

Title: Peripheral relaxant activity of apomorphine and of a D1 selective receptor agonist on human corpus cavernosum strips.

Journal: International journal of impotence research 20050101

Title: Loss of endothelium-dependent relaxation in abdominal aorta preserved in a co-storage system.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050101

Title: Species differences in the effects of prostanoids on MAP kinase phosphorylation, myosin light chain phosphorylation and contraction in bovine and cat iris sphincter smooth muscle.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20050101

Title: Acute impairment of contractile responses by 17beta-estradiol is cAMP and protein kinase G dependent in vascular smooth muscle cells of the porcine coronary arteries.

Journal: British journal of pharmacology 20050101

Title: The intracellular action of sphingosine 1-phosphate in GPVI-mediated Ca2+ mobilization in platelets.

Journal: Thrombosis research 20050101

Title: Cardiopulmonary effects of chronic administration of the NO synthase inhibitor L-NAME in the chick embryo.

Journal: Biology of the neonate 20050101

Title: Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17.

Journal: FEBS letters 20041203

Title: Pulmonary vascular effects of red blood cells containing S-nitrosated hemoglobin.

Journal: American journal of physiology. Heart and circulatory physiology 20041201

Title: Chronic hypoxia inhibits contraction of fetal arteries by increased endothelium-derived nitric oxide and prostaglandin synthesis.

Journal: Journal of the Society for Gynecologic Investigation 20041201

Title: Effect of selective inhibition of the p38 MAP kinase pathway on platelet aggregation.

Journal: Thrombosis and haemostasis 20041201

Title: Calcium dynamics in cortical astrocytes and arterioles during neurovascular coupling.

Journal: Circulation research 20041112

Title: Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction.

Journal: Circulation research 20041112

Title: Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy.

Journal: Circulation 20041102

Title: Intratracheal adenoviral-mediated delivery of iNOS decreases pulmonary vasoconstrictor responses in rats.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041101

Title: Glycoprotein VI/Fc receptor gamma chain-independent tyrosine phosphorylation and activation of murine platelets by collagen.

Journal: The Biochemical journal 20041101

Title: Contractile responses of isolated rat mesenteric arteries to acute episodes of severe hypoxia and subsequent reoxygenation.

Journal: Microvascular research 20041101

Title: Vascular endothelial growth factor-induced nitric oxide- and PGI2-dependent relaxation in human internal mammary arteries: a comparative study with KDR and Flt-1 selective mutants.

Journal: Journal of cardiovascular pharmacology 20041101

Title: Tezosentan, a combined parenteral endothelin receptor antagonist, produces pulmonary vasodilation in lambs with acute and chronic pulmonary hypertension.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20041101

Title: Effects of norepinephrine on alpha-subtype receptors in the feline pulmonary vascular bed.

Journal: Critical care medicine 20041101

Title: Unresponsiveness of platelets lacking both Galpha(q) and Galpha(13). Implications for collagen-induced platelet activation.

Journal: The Journal of biological chemistry 20041029

Title: Genistein reduces agonist-induced contractions of porcine coronary arterial smooth muscle in a cyclic AMP-dependent manner.

Journal: European journal of pharmacology 20041025

Title: Soluble guanylate cyclase activator reverses acute pulmonary hypertension and augments the pulmonary vasodilator response to inhaled nitric oxide in awake lambs.

Journal: Circulation 20041012

Title: A platelet secretion pathway mediated by cGMP-dependent protein kinase.

Journal: The Journal of biological chemistry 20041008

Title: Effects of a new phosphodiesterase enzyme type V inhibitor (UK 343-664) versus milrinone in a porcine model of acute pulmonary hypertension.

Journal: The Annals of thoracic surgery 20041001

Title: Synergism between cysteinyl leukotrienes and thromboxane A2 to induce allergic late phase nasal blockage in guinea pigs.

Journal: Prostaglandins & other lipid mediators 20041001

Title: [Role of ROK in contraction of rat femoral arteries after 14 d tail suspension].

Journal: Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20041001

Title: Vascular effects of the Mangifera indica L. extract (Vimang).

Journal: European journal of pharmacology 20040924

Title: Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism.

Journal: The Journal of pharmacology and experimental therapeutics 20040901

Title: Novel diacylglycerol kinase inhibitor selectively suppressed an U46619-induced enhancement of mouse portal vein contraction under high glucose conditions.

Journal: British journal of pharmacology 20040901

Title: Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries.

Journal: Hypertension (Dallas, Tex. : 1979) 20040901

Title: Effect of the statin atorvastatin on intracellular signalling by the prostacyclin receptor in vitro and in vivo.

Journal: British journal of pharmacology 20040901

Title: Local anesthetics inhibit thromboxane A2 signaling in Xenopus oocytes and human k562 cells.

Journal: Anesthesia and analgesia 20040901

Title: Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration.

Journal: Circulation research 20040820

Title: In vitro effects of antihypertensive drugs on thromboxane agonist (U46619)-induced vasoconstriction in human internal mammary artery.

Journal: British journal of anaesthesia 20040801

Title: Characterization of purine receptors in mouse thoracic aorta.

Journal: Journal of cardiovascular pharmacology 20040801

Title: Propofol inhibits human platelet aggregation induced by proinflammatory lipid mediators.

Journal: Anesthesia and analgesia 20040801

Title: Effects of PGI2 and TxA2 analogs and inhibitors in orthodontic tooth movement.

Journal: The Angle orthodontist 20040801

Title: Extracellular superoxide enhances 5-HT-induced murine pulmonary artery vasoconstriction.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040701

Title: Effect of aerosolized milrinone during drug-induced pulmonary hypertension in lambs.

Journal: Pharmacological research 20040701

Title: Muscarinic (M) receptors in coronary circulation: gene-targeted mice define the role of M2 and M3 receptors in response to acetylcholine.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040701

Title: Raloxifene relaxes rat cerebral arteries in vitro and inhibits L-type voltage-sensitive Ca2+ channels.

Journal: Stroke 20040701

Title: ADP secretion and subsequent P2Y12 receptor signalling play a crucial role in thrombin-induced ERK2 activation in human platelets.

Journal: Thrombosis and haemostasis 20040701

Title: Bupivacaine inhibits thromboxane A2-induced vasoconstriction in rat thoracic aorta.

Journal: Anesthesia and analgesia 20040701

Title: ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation.

Journal: The Journal of biological chemistry 20040625

Title: Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors.

Journal: Circulation research 20040625

Title: Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis.

Journal: Circulation research 20040625

Title: Enhanced contractility of renal afferent arterioles from angiotensin-infused rabbits: roles of oxidative stress, thromboxane prostanoid receptors, and endothelium.

Journal: Circulation research 20040611

Title: Reoxygenation-induced constriction in murine coronary arteries: the role of endothelial NADPH oxidase (gp91phox) and intracellular superoxide.

Journal: The Journal of biological chemistry 20040604

Title: Cyclopiazonic acid decreases spontaneous transient depolarizations in guinea pig mesenteric lymphatic vessels in endothelium-dependent and -independent manners.

Journal: American journal of physiology. Heart and circulatory physiology 20040601

Title: Glucose-dependent enhancement of spontaneous phasic contraction is suppressed in diabetic mouse portal vein: association with diacylglycerol-protein kinase C pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20040601

Title: Cyclooxygenase involvement in thromboxane-dependent contraction in rat mesenteric resistance arteries.

Journal: Hypertension (Dallas, Tex. : 1979) 20040601

Title: Mer receptor tyrosine kinase signaling participates in platelet function.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040601

Title: ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta.

Journal: British journal of pharmacology 20040601

Title: Mechanism of collagen activation in human platelets.

Journal: The Journal of biological chemistry 20040507

Title: Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501

Title: Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice.

Journal: Hypertension (Dallas, Tex. : 1979) 20040501

Title: Thromboxane receptor stimulation associated with loss of SKCa activity and reduced EDHF responses in the rat isolated mesenteric artery.

Journal: British journal of pharmacology 20040501

Title: EP1- and FP-mediated cross-desensitization of the alpha (alpha) and beta (beta) isoforms of the human thromboxane A2 receptor.

Journal: British journal of pharmacology 20040501

Title: Sex hormone regulation of systemic endothelial and renal microvascular reactivity in type-2 diabetes: studies in gonadectomized and sham-operated Zucker diabetic rats.

Journal: European journal of clinical investigation 20040501

Title: Excitatory action of prostanoids on the ferret isolated vagus nerve preparation.

Journal: European journal of pharmacology 20040426

Title: Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery.

Journal: European journal of pharmacology 20040426

Title: Na(+) pump alpha 2-isoform specifically couples to contractility in vascular smooth muscle: evidence from gene-targeted neonatal mice.

Journal: American journal of physiology. Cell physiology 20040401

Title: A bronchial epithelium-derived factor reduces pulmonary vascular tone in the newborn rat.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20040401

Title: Altered pulmonary vascular reactivity in mice with excessive erythrocytosis.

Journal: American journal of respiratory and critical care medicine 20040401

Title: Restoration of blood pressure by centrally injected U-46619, a thromboxane A(2) analog, in hemorrhaged hypotensive rats: investigation of different brain areas.

Journal: Pharmacology 20040401

Title: Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF.

Journal: British journal of pharmacology 20040401

Title: The regulation of interleukin-6 secretion by prostanoids and members of the tumor necrosis factor superfamily in fresh villous fragments of term human placenta.

Journal: Journal of the Society for Gynecologic Investigation 20040401

Title: Purification and characterization of recombinant human prostacyclin synthase.

Journal: Journal of biochemistry 20040401

Title: Pharmacology of the mouse-isolated cerebral artery.

Journal: Vascular pharmacology 20040401

Title: Nickel inhibits urocortin-induced relaxation in the rat pulmonary artery.

Journal: European journal of pharmacology 20040319

Title: Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor.

Journal: Archives of biochemistry and biophysics 20040315

Title: Pyrimidine nucleotides suppress KDR currents and depolarize rat cerebral arteries by activating Rho kinase.

Journal: American journal of physiology. Heart and circulatory physiology 20040301

Title: Alteration in endothelin receptor sub-type responsiveness and in the endothelin-TXA(2) mimetic U46619 interaction, in type-2 hypertensive diabetic Zucker rats.

Journal: Diabetes research and clinical practice 20040301

Title: 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils.

Journal: The Journal of biological chemistry 20040227

Title: Thromboxane A2 (TP) receptor in the non-pregnant porcine myometrium and its role in regulation of spontaneous contractile activity.

Journal: European journal of pharmacology 20040206

Title: In vitro vasodilator mechanisms of the indole alkaloids rhynchophylline and isorhynchophylline, isolated from the hook of Uncaria rhynchophylla (Miquel).

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040201

Title: Vascular oxygen sensing: detection of novel candidates by proteomics and organ culture.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20040201

Title: Iloprost inhibits superoxide formation and gp91phox expression induced by the thromboxane A2 analogue U46619, 8-isoprostane F2alpha, prostaglandin F2alpha, cytokines and endotoxin in the pig pulmonary artery.

Journal: British journal of pharmacology 20040201

Title: Comparison of U46619-, endothelin-1- or phenylephrine-induced changes in cellular Ca2+ profiles and Ca2+ sensitisation of constriction of pressurised rat resistance arteries.

Journal: British journal of pharmacology 20040201

Title: EP4 prostanoid receptor-mediated vasodilatation of human middle cerebral arteries.

Journal: British journal of pharmacology 20040201

Title: Pulmonary responses to selective phosphodiesterase-5 and phosphodiesterase-3 inhibitors.

Journal: Chest 20040201

Title: Nociceptin/orphanin FQ alters prostaglandin cerebrovascular action following brain injury.

Journal: Journal of neurotrauma 20040201

Title: Basic features of hypoxic pulmonary vasoconstriction in mice.

Journal: Respiratory physiology & neurobiology 20040115

Title: Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.

Journal: FEBS letters 20040102

Title: Thromboxane receptor analog, U-46619, redistributes pulmonary microvascular perfusion in isolated rat lungs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20040101

Title: The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats.

Journal: British journal of pharmacology 20040101

Title: Heterogeneity of neuronal and smooth muscle receptors involved in the VIP- and PACAP-induced relaxations of the pig intravesical ureter.

Journal: British journal of pharmacology 20040101

Title: Pharmacologically distinct intracellular calcium pools regulate tonic and oscillatory responses in porcine thoracic duct.

Journal: Journal of cardiovascular pharmacology 20040101

Title: Urocortin protects coronary endothelial function during ischemia-reperfusion: a brief communication.

Journal: Experimental biology and medicine (Maywood, N.J.) 20040101

Title: Glibenclamide inhibits thromboxane-mediated vasoconstriction by thromboxane receptor blockade.

Journal: Vascular pharmacology 20040101

Title: Effects of platelet-activating factor and thromboxane A2 on isolated perfused guinea pig liver.

Journal: Prostaglandins & other lipid mediators 20040101

Title: Endothelium-dependent responses in small human mesenteric arteries.

Journal: Physiological research 20040101

Title: Down-regulation of lipoxin A4 receptor by thromboxane A2 signaling in RAW246.7 cells in vitro and bleomycin-induced lung fibrosis in vivo.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20040101

Title: Inhibitory activity of shiitake flavor against platelet aggregation.

Journal: BioFactors (Oxford, England) 20040101

Title: Role of p38 mitogen-activated protein kinase in thrombus formation.

Journal: Journal of receptor and signal transduction research 20040101

Title: Hypoxic and pharmacological preconditioning preserves vasomotor response of porcine coronary artery.

Journal: Polish journal of pharmacology 20040101

Title: Emetic action of the prostanoid TP receptor agonist, U46619, in Suncus murinus (house musk shrew).

Journal: European journal of pharmacology 20031215

Title: Fibroblast fiber contraction: role of C and Rho kinase in activation by thromboxane A2.

Journal: American journal of physiology. Cell physiology 20031201

Title: Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20031201

Title: Role of COX-1 and -2 in prostanoid generation and modulation of angiotensin II responses.

Journal: American journal of physiology. Heart and circulatory physiology 20031201

Title: Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: a study in human and porcine arteries.

Journal: Journal of hypertension 20031201

Title: 5-hydroxytryptamine and thromboxane A2 as physiologic mediators of human umbilical artery closure.

Journal: Journal of the Society for Gynecologic Investigation 20031201

Title: Evidence for nonadrenoceptor responses to imidazoline derivatives in the porcine isolated rectal artery.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.

Journal: European journal of pharmacology 20031114

Title: Thromboxane A2 regulates vascular tone via its inhibitory effect on the expression of inducible nitric oxide synthase.

Journal: Circulation 20031111

Title: Effect of 8-isoprostaglandin F2alpha on the newborn rat pulmonary arterial muscle and endothelium.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20031101

Title: Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery.

Journal: British journal of pharmacology 20031101

Title: Intermittent nitric oxide combined with intravenous dipyridamole in a piglet model of acute pulmonary hypertension.

Journal: Anesthesia and analgesia 20031101

Title: Red wine prevents homocysteine-induced endothelial dysfunction in porcine coronary arteries.

Journal: The Journal of surgical research 20031101

Title: Sildenafil prevents change in RhoA expression induced by chronic hypoxia in rat pulmonary artery.

Journal: Circulation research 20031003

Title: Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta.

Journal: Circulation research 20031003

Title: Ketamine inhibits endotoxin-induced inositol 1,4,5-triphosphate in rat ventricular cardiomyocytes.

Journal: Intensive care medicine 20031001

Title: Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung.

Journal: The Journal of pharmacology and experimental therapeutics 20031001

Title: Inhibitors of 20-hydroxyeicosatetraenoic acid reduce renal vasoconstrictor responsiveness.

Journal: The Journal of pharmacology and experimental therapeutics 20031001

Title: Involvement of tyrosine kinase pathway in acute hypoxic vasoconstriction in sheep isolated pulmonary vein.

Journal: Vascular pharmacology 20031001

Title: Mechanisms involved in the early increase of serotonin contraction evoked by endotoxin in rat middle cerebral arteries.

Journal: British journal of pharmacology 20031001

Title: Myometrial and placental artery reactivity alone cannot explain reduced placental perfusion in pre-eclampsia and intrauterine growth restriction.

Journal: BJOG : an international journal of obstetrics and gynaecology 20031001

Title: Difference in signal transduction mechanisms involved in 5-hydroxytryptamine- and U46619-induced vasoconstrictions.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20031001

Title: Action of prostanoids on the emetic reflex of Suncus murinus (the house musk shrew).

Journal: European journal of pharmacology 20030923

Title: Alterations in pulmonary vascular function in rats exposed to intermittent hypoxia.

Journal: European journal of pharmacology 20030912

Title: Ephedrine in the cat lung vasculature.

Journal: Acta anaesthesiologica Scandinavica 20030901

Title: Recombinant protein 1/secretoglobin 1A1 participates in the actin polymerization of human platelets.

Journal: Clinica chimica acta; international journal of clinical chemistry 20030901

Title: Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas.

Journal: Archives of pharmacal research 20030901

Title: Diversity of signaling underlying responses mediated by selective activation of the platelet thromboxane A2 (TXA2) receptor; pharmacological and kinetic studies in vitro.

Journal: Platelets 20030901

Title: Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.

Journal: The Journal of biological chemistry 20030815

Title: Effect of low doses of ethanol on platelet function in long-life abstainers and moderate-wine drinkers.

Journal: Life sciences 20030808

Title: Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation.

Journal: European journal of pharmacology 20030808

Title: Pharmacological characterization of prostanoid receptors mediating vasoconstriction in human umbilical vein.

Journal: British journal of pharmacology 20030802

Title: Effects of in vivo lipopolysaccharide infusion on vasoconstrictor function of rat isolated mesentery, kidney, and aorta.

Journal: The Journal of pharmacology and experimental therapeutics 20030801

Title: Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling.

Journal: British journal of pharmacology 20030801

Title: Melatonin inhibits nitrate tolerance in isolated coronary arteries.

Journal: British journal of pharmacology 20030801

Title: TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets.

Journal: Journal of thrombosis and haemostasis : JTH 20030801

Title: Zardaverine and aerosolised iloprost in a model of acute respiratory failure.

Journal: The European respiratory journal 20030801

Title: Detrimental vascular effects of lysophosphatidylcholine is limited by other phospholipid components of low-density lipoprotein.

Journal: Molecular and cellular biochemistry 20030801

Title: The induction and detection in vitro of iNOS in the porcine basilar artery.

Journal: Journal of immunological methods 20030801

Title: Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation.

Journal: Blood 20030715

Title: 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation.

Journal: American journal of physiology. Heart and circulatory physiology 20030701

Title: Functional comparison of the antagonistic properties of some Angiotensin II type 1 receptor blockers on the contraction elicited by Angiotensin II and thromboxane A2 on human saphenous veins.

Journal: Journal of cardiovascular pharmacology 20030701

Title: Vascular reactivity of the preplacental vasculature in Guinea pigs.

Journal: Placenta 20030701

Title: Inhibition of myocardial apoptosis reduces infarct size and improves regional contractile dysfunction during reperfusion.

Journal: Cardiovascular research 20030701

Title: Impaired endothelium-derived hyperpolarizing factor-mediated relaxation in porcine pulmonary microarteries after cold storage with Euro-Collins and University of Wisconsin solutions.

Journal: The Journal of thoracic and cardiovascular surgery 20030701

Title: High-glucose enhances a thromboxane A2-induced aortic contraction mediated by an alteration of phosphatidylinositol turnover.

Journal: Journal of pharmacological sciences 20030701

Title: Effects of U-46619 on pulmonary hemodynamics before and after administration of BM-573, a novel thromboxane A2 inhibitor.

Journal: Archives of physiology and biochemistry 20030701

Title: Effect of steady versus oscillating flow on porcine coronary arterioles: involvement of NO and superoxide anion.

Journal: Circulation research 20030627

Title: An important role for the Na+-Ca2+ exchanger in the decrease in cytosolic Ca2+ concentration induced by isoprenaline in the porcine coronary artery.

Journal: The Journal of physiology 20030601

Title: Rho-Rho kinase pathway is involved in the regulation of myogenic tone and pump activity in isolated lymph vessels.

Journal: American journal of physiology. Heart and circulatory physiology 20030601

Title: Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.

Journal: Kidney international 20030601

Title: Insurmountable antagonism of AT-1015, a 5-HT2 antagonist, on serotonin-induced endothelium-dependent relaxation in porcine coronary artery.

Journal: The Journal of pharmacy and pharmacology 20030601

Title: Enhanced vasoconstrictor responses in eNOS deficient mice.

Journal: Nitric oxide : biology and chemistry 20030601

Title: Estrogen-induced augmentation of endothelium-dependent nitric oxide-mediated vasodilation in isolated rat cerebral small arteries.

Journal: The Japanese journal of physiology 20030601

Title: What leads to different mediators of alkalosis-induced vasodilation in isolated and in situ pulmonary vessels?

Journal: American journal of physiology. Lung cellular and molecular physiology 20030501

Title: Airway smooth muscle changes in the nitrofen-induced congenital diaphragmatic hernia rat model.

Journal: Pediatric research 20030501

Title: Thrombopoietin increases platelet adhesion under flow and decreases rolling.

Journal: British journal of haematology 20030501

Title: Enhancement of alpha2-adrenoceptor-mediated vasoconstriction by the thromboxane-mimetic U46619 in the porcine isolated ear artery: role of the ERK-MAP kinase signal transduction cascade.

Journal: British journal of pharmacology 20030501

Title: The promoting effect of epinephrine on lipopolysaccharide-induced interleukin-8 production in whole blood may be mediated by thromboxane A2.

Journal: Journal of thrombosis and haemostasis : JTH 20030501

Title: Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401

Title: Chronic exposure to TXA2 increases expression of ROCKI in human myometrial cells.

Journal: Prostaglandins & other lipid mediators 20030401

Title: Prostanoid-induced modulation of neuropeptide Y and noradrenaline release from the rat mesenteric bed.

Journal: Autonomic & autacoid pharmacology 20030401

Title: Resonance Raman investigation of the interaction of thromboxane synthase with substrate analogues.

Journal: Biochemistry 20030311

Title: Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.

Journal: Circulation research 20030307

Title: Role of serotonin in thromboxane A2-induced coronary chemoreflex.

Journal: American journal of physiology. Heart and circulatory physiology 20030301

Title: Downregulation of hypoxic vasoconstriction by chronic hypoxia in rabbits: effects of nitric oxide.

Journal: American journal of physiology. Heart and circulatory physiology 20030301

Title: Enhancement effect under high-glucose conditions on U46619-induced spontaneous phasic contraction in mouse portal vein.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: Antiplatelet activities of aporphine alkaloids isolated from leaves of Magnolia obovata.

Journal: Planta medica 20030301

Title: Thiorphan enhances bradykinin-induced vascular relaxation in hypoxic/hyperkalaemic porcine coronary artery.

Journal: The Journal of pharmacy and pharmacology 20030301

Title: PKD: a new protein kinase C-dependent pathway in platelets.

Journal: Blood 20030215

Title: Effects of diabetes on the vascular response to nitric oxide and constrictor prostanoids: gender and regional differences.

Journal: Life sciences 20030214

Title: Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.

Journal: American journal of physiology. Lung cellular and molecular physiology 20030201

Title: Amplification of sumatriptan-induced contraction in rabbit saphenous vein but not in basilar artery.

Journal: American journal of physiology. Heart and circulatory physiology 20030201

Title: Responses to human CGRP, ADM, and PAMP in human thymic arteries.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030201

Title: The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery.

Journal: Anesthesia and analgesia 20030201

Title: Contributions of nitric oxide and prostanoids and their signaling pathways to the renal medullary vasodilator effect of U46619 (9-11-dideoxy-11 alpha,9a-epoxymethano-prostaglandin F(2a)) in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: Gender difference in vascular and platelet reactivity to thromboxane A(2)-mimetic U46619 and to endothelial dependent vasodilation in Zucker fatty (hypertensive, hyperinsulinemic) diabetic rats.

Journal: Diabetes research and clinical practice 20030101

Title: Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist.

Journal: The Journal of pharmacology and experimental therapeutics 20030101

Title: Contribution of K+ channels to relaxation induced by 17beta-estradiol but not by progesterone in isolated rat mesenteric artery rings.

Journal: Journal of cardiovascular pharmacology 20030101

Title: Vascular reactivity of pulmonary arteries from premature lambs subjected to liquid ventilation.

Journal: Biology of the neonate 20030101

Title: Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets.

Journal: The Journal of biological chemistry 20021206

Title: Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation.

Journal: The Biochemical journal 20021201

Title: Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine.

Journal: British journal of pharmacology 20021201

Title: Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension.

Journal: Acta pharmacologica Sinica 20021201

Title: Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2.

Journal: British journal of pharmacology 20021201

Title: THG113: a novel selective FP antagonist that delays preterm labor.

Journal: Seminars in perinatology 20021201

Title: Beta2 integrin-dependent neutrophil adhesion induced by minimally modified low-density lipoproteins is mainly mediated by F2-isoprostanes.

Journal: Circulation 20021105

Title: Intravenous dipyridamole enhances the effects of inhaled nitric oxide and prevents rebound pulmonary hypertension in piglets.

Journal: Pediatric research 20021101

Title: Morphine-potentiated agonist-induced platelet aggregation through alpha2-adrenoceptors in human platelets.

Journal: Journal of cardiovascular pharmacology 20021101

Title: Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets.

Journal: The Journal of biological chemistry 20021018

Title: Comparative responses to alpha,beta-methylene-ATP in cat pulmonary, mesenteric, and hindquarter vascular beds.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20021001

Title: Rate of NO scavenging alters effects of recombinant hemoglobin solutions on pulmonary vasoreactivity.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20021001

Title: In the presence of L-NAME SERCA blockade induces endothelium-dependent contraction of mouse aorta through activation of smooth muscle prostaglandin H2/thromboxane A2 receptors.

Journal: British journal of pharmacology 20021001

Title: Angiotensin II constriction of rat vasa recta is partially thromboxane dependent.

Journal: Hypertension (Dallas, Tex. : 1979) 20021001

Title: Plasma-mediated potentiation in prostanoid-induced contractions in isolated canine external jugular veins.

Journal: The Japanese journal of physiology 20021001

Title: Weak platelet agonists and U46619 induce apoptosis-like events in platelets, in the absence of phosphatidylserine exposure.

Journal: Thrombosis research 20020915

Title: Desensitization of the mouse thromboxane A2 receptor (TP) by G protein-coupled receptor kinases (Grks).

Journal: Prostaglandins & other lipid mediators 20020901

Title: [Influence of labetalol on the resistance of human fetoplacental vessels in perfusion in vitro].

Journal: Ginekologia polska 20020901

Title: Mechanisms of bradykinin-mediated dilation in newborn piglet pulmonary conducting and resistance vessels.

Journal: American journal of physiology. Lung cellular and molecular physiology 20020801

Title: Vascular responses in vivo to 8-epi PGF(2alpha) in normal and hypercholesterolemic pigs.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020801

Title: Vascular activities of prostaglandins and selective prostanoid receptor agonists in human retinal microvessels.

Journal: Experimental eye research 20020801

Title: Pulmonary endothelial dysfunction after cardiopulmonary bypass in neonatal pigs.

Journal: Acta anaesthesiologica Scandinavica 20020801

Title: Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow.

Journal: Pediatric research 20020801

Title: The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women.

Journal: British journal of pharmacology 20020801

Title: Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism.

Journal: American journal of respiratory and critical care medicine 20020715

Title: Relaxant effects of selective phosphodiesterase inhibitors on U46619 precontracted human intralobar pulmonary arteries and role of potassium channels.

Journal: Journal of cardiovascular pharmacology 20020701

Title: The effect of tumor necrosis factor-alpha on microvascular permeability in an isolated, perfused lung.

Journal: Shock (Augusta, Ga.) 20020701

Title: Membrane currents in canine bronchial artery and their regulation by excitatory agonists.

Journal: American journal of physiology. Lung cellular and molecular physiology 20020601

Title: Platelet-erythrocyte interactions enhance alpha(IIb)beta(3) integrin receptor activation and P-selectin expression during platelet recruitment: down-regulation by aspirin ex vivo.

Journal: Blood 20020601

Title: U-46619-induced potentiation of noradrenergic constriction in the human saphenous vein: antagonism by thromboxane receptor blockade.

Journal: Cardiovascular research 20020601

Title: Interleukin-10 protects nitric oxide-dependent relaxation during diabetes: role of superoxide.

Journal: Diabetes 20020601

Title: An analysis of responses to levosimendan in the pulmonary vascular bed of the cat.

Journal: Anesthesia and analgesia 20020601

Title: Vascular effects of a soy leaves (Glycine max) extract and kaempferol glycosides in isolated rat carotid arteries.

Journal: Planta medica 20020601

Title: 14,15-Epoxyeicosa-5(Z)-enoic acid: a selective epoxyeicosatrienoic acid antagonist that inhibits endothelium-dependent hyperpolarization and relaxation in coronary arteries.

Journal: Circulation research 20020517

Title: Synthesis and biological activity of 1-phenylsulfonyl-4-phenylsulfonylaminopyrrolidine derivatives as thromboxane a(2) receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20020501

Title: Effects of STA(2), a thromboxane A(2) mimetic, in inducing airflow obstruction and airway microvascular leakage in guinea pigs.

Journal: Pharmacology 20020501

Title: 14,15-Dihydroxyeicosatrienoic acid relaxes bovine coronary arteries by activation of K(Ca) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20020501

Title: Chronic hypoxia increases MCA contractile response to U-46619 by reducing NO production and/or activity.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020501

Title: A new family of thromboxane receptor antagonists with secondary thromboxane synthase inhibition.

Journal: The Journal of pharmacology and experimental therapeutics 20020501

Title: Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha.

Journal: Thrombosis and haemostasis 20020501

Title: Role of prostacyclin in the cardiovascular response to thromboxane A2.

Journal: Science (New York, N.Y.) 20020419

Title: The roles of LAT in platelet signaling induced by collagen, TxA2, or ADP.

Journal: Biochemical and biophysical research communications 20020412

Title: A Gi-dependent pathway is required for activation of the small GTPase Rap1B in human platelets.

Journal: The Journal of biological chemistry 20020405

Title: Regulation of extracellular signal-regulated kinase cascades by alpha- and beta-isoforms of the human thromboxane A(2) receptor.

Journal: Molecular pharmacology 20020401

Title: Isoflurane does not further impair microvascular vasomotion in a rat model of subarachnoid hemorrhage.

Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20020401

Title: Inhibition by prostaglandin E(2) of anaphylatoxin C5a- but not zymosan-induced prostanoid release from rat Kupffer cells.

Journal: Laboratory investigation; a journal of technical methods and pathology 20020401

Title: Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria.

Journal: Planta medica 20020401

Title: Release from intracellular stores is responsible for calcium signaling with von Willebrand factor in human platelets.

Journal: Thrombosis and haemostasis 20020401

Title: Effect of melatonin on vascular responses of porcine ciliary arteries.

Journal: Current eye research 20020401

Title: Role of thromboxane receptors in the dipsogenic response to central angiotensin II.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020301

Title: Response of rat thoracic aorta to F(2)-isoprostane metabolites.

Journal: Journal of cardiovascular pharmacology 20020301

Title: The role of inducible nitric oxide synthase in lipopolysaccharide-mediated hyporeactivity to vasoconstrictors differs among isolated rat arteries.

Journal: Clinical science (London, England : 1979) 20020301

Title: Downregulation of nitric oxide accumulation by cyclooxygenase-2 induction and thromboxane A2 production in interleukin-1beta-stimulated rat aortic smooth muscle cells.

Journal: Journal of hypertension 20020301

Title: Thromboxane A(2) mimetic evokes a bradycardia mediated by stimulation of cardiac vagal afferent nerves.

Journal: American journal of physiology. Heart and circulatory physiology 20020201

Title: Vascular effects of poly-N-acetylglucosamine in isolated rat aortic rings.

Journal: The Journal of surgical research 20020201

Title: Nongenomic vasodilator action of progesterone on primate coronary arteries.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020201

Title: Sex-specific acute effect of estrogen on endothelium-derived contracting factor in the renal artery of hypertensive Dahl rats.

Journal: Journal of hypertension 20020201

Title: An investigation of the effect of the prostaglandin EP2 receptor agonist, butaprost, on the human isolated myometrium from pregnant and non-pregnant women.

Journal: The Journal of endocrinology 20020201

Title: Indomethacin protects permeability barrier from focal segmental glomerulosclerosis serum.

Journal: Kidney international 20020201

Title: Vascular reactivity to angiotensin II alone or combined with a thromboxane A2 mimetic in the isolated perfused kidney of Lyon hypertensive rats.

Journal: Fundamental & clinical pharmacology 20020201

Title: Inhibition of vasomotion in hippocampal cerebral arterioles during increases in neuronal activity.

Journal: Autonomic neuroscience : basic & clinical 20020110

Title: Pulsation-induced dilation of subendocardial and subepicardial arterioles: effect on vasodilator sensitivity.

Journal: American journal of physiology. Heart and circulatory physiology 20020101

Title: Thromboxane receptor signalling in human myometrial cells.

Journal: Prostaglandins & other lipid mediators 20020101

Title: Homocysteine decreases endothelium-dependent vasorelaxation in porcine arteries.

Journal: The Journal of surgical research 20020101

Title: Prostaglandin endoperoxides and thromboxane A2 activate the same receptor isoforms in human platelets.

Journal: Thrombosis and haemostasis 20020101

Title: Potentiation of human lung fibroblast chemotaxis by the thromboxane A(2) analog U-46619.

Journal: The Journal of laboratory and clinical medicine 20020101

Title: Organ culture: a new model for vascular endothelium dysfunction.

Journal: BMC cardiovascular disorders 20020101

Title: Prostaglandin E(2) inhibits replication of HIV-1 in macrophages through activation of protein kinase A.

Journal: Cellular immunology 20020101

Title: Increased NO-mediated and reduced TxA2-dependent responses in skeletal muscle arterioles in pregnancy.

Journal: Hypertension in pregnancy 20020101

Title: p38 mitogen-activated protein kinase activation is required for thromboxane- induced contraction in perfused and pressurized rat mesenteric resistance arteries.

Journal: Journal of vascular research 20020101

Title: Carbon monoxide decreases perfusion pressure in isolated human placenta.

Journal: Placenta 20020101

Title: Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides.

Journal: The Journal of biological chemistry 20011221

Title: Influence of magnesium sulphate and isradipine on human placental cotyledon fetal vessels in vitro.

Journal: European journal of obstetrics, gynecology, and reproductive biology 20011210

Title: Combination of nonspecific PDE inhibitors with inhaled prostacyclin in experimental pulmonary hypertension.

Journal: American journal of physiology. Lung cellular and molecular physiology 20011201

Title: Homogeneous segmental profile of carbon monoxide-mediated pulmonary vasodilation in rats.

Journal: American journal of physiology. Lung cellular and molecular physiology 20011201

Title: A beta-peptides enhance vasoconstriction in cerebral circulation.

Journal: American journal of physiology. Heart and circulatory physiology 20011201

Title: U-46619-induced potentiation of noradrenergic constriction in the human saphenous vein: antagonism by thromboxane receptor blockade.

Journal: Cardiovascular research 20011201

Title: Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins.

Journal: British journal of pharmacology 20011201

Title: [Ramatroban (Baynas): a review of its pharmacological and clinical profile].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011201

Title: Effects of P2Y(1) and P2Y(12) receptor antagonists on platelet aggregation induced by different agonists in human whole blood.

Journal: Platelets 20011101

Title: Local anesthetic actions on thromboxane-induced platelet aggregation.

Journal: Anesthesia and analgesia 20011101

Title: Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels.

Journal: British journal of pharmacology 20011101

Title: Coaerosolization of phosphodiesterase inhibitors markedly enhances the pulmonary vasodilatory response to inhaled iloprost in experimental pulmonary hypertension. Maintenance of lung selectivity.

Journal: American journal of respiratory and critical care medicine 20011101

Title: Progesterone regulation of vascular thromboxane A(2) receptors in rhesus monkeys.

Journal: American journal of physiology. Heart and circulatory physiology 20011001

Title: Differential effects of U46619 on renal regional hemodynamics in the rat: involvement of endothelin.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Pulmonary artery vasoconstriction but not [Ca2+]i signal stimulated by thromboxane A2 is partially resistant to NO.

Journal: Pediatric research 20011001

Title: Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways.

Journal: British journal of pharmacology 20011001

Title: Mechanism of trypsin-induced endothelium-dependent vasorelaxation in the porcine coronary artery.

Journal: British journal of pharmacology 20011001

Title: Dominant role of an endothelium-derived hyperpolarizing factor (EDHF)-like vasodilator in the ciliary vascular bed of the bovine isolated perfused eye.

Journal: British journal of pharmacology 20011001

Title: An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide.

Journal: Hypertension (Dallas, Tex. : 1979) 20011001

Title: Biogenesis of G-protein mediated calcium signaling in human megakaryocytes.

Journal: Thrombosis and haemostasis 20011001

Title: Increased bleeding tendency and decreased susceptibility to thromboembolism in mice lacking the prostaglandin E receptor subtype EP(3).

Journal: Circulation 20010904

Title: Inhibitory effects of brefeldin A, a membrane transport blocker, on the bradykinin-induced hyperpolarization-mediated relaxation in the porcine coronary artery.

Journal: British journal of pharmacology 20010901

Title: Inhibition of vasoconstriction by AJ-2615, a novel calcium antagonist with alpha(1)-adrenergic receptor blocking activity in human conduit arteries used as bypass grafts.

Journal: British journal of clinical pharmacology 20010901

Title: Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20010901

Title: Potentiation of sympathetic neurotransmission in bovine isolated irides by isoprostanes.

Journal: Free radical research 20010901

Title: Rho activation in excitatory agonist-stimulated vascular smooth muscle.

Journal: American journal of physiology. Cell physiology 20010801

Title: 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010801

Title: Identification and functional characterization of thromboxane A2 receptors in Schwann cells.

Journal: Journal of neurochemistry 20010801

Title: Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication.

Journal: American journal of respiratory cell and molecular biology 20010801

Title: Activity of a novel dual thromboxane A(2)receptor antagonist and thromboxane synthase inhibitor (BM-573) on platelet function and isolated smooth muscles.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010801

Title: Endothelial dysfunction induced by oxidized low-density lipoproteins in isolated mouse aorta: a comparison with apolipoprotein-E deficient mice.

Journal: European journal of pharmacology 20010720

Title: Prostaglandin D(2) receptor-mediated desensitization of the alpha isoform of the human thromboxane A(2) receptor.

Journal: Biochemical pharmacology 20010715

Title: Hypoxic vasodilation in porcine coronary artery is preferentially inhibited by organ culture.

Journal: American journal of physiology. Cell physiology 20010701

Title: Presynaptic alpha7-nicotinic acetylcholine receptors mediate nicotine-induced nitric oxidergic neurogenic vasodilation in porcine basilar arteries.

Journal: The Journal of pharmacology and experimental therapeutics 20010701

Title: A functional study on prostanoid receptors involved in cultured human iridal melanocyte stimulation.

Journal: Experimental eye research 20010701

Title: Vasoactive effects of 8-epi-prostaglandin F(2alpha)in isolated human placental conduit and resistance blood vessels in vitro.

Journal: Placenta 20010701

Title: Inhibition of cyclooxygenase but not nitric oxide synthase influences effects on the human omental artery of the thromboxane A2 mimetic U46619 and 17beta-estradiol.

Journal: American journal of obstetrics and gynecology 20010701

Title: Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing.

Journal: Circulation research 20010622

Title: Distinct pathways of Ca(2+) sensitization in porcine coronary artery: effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca(2+).

Journal: Circulation research 20010622

Title: Shear stress-induced vasodilation in porcine coronary conduit arteries is independent of nitric oxide release.

Journal: American journal of physiology. Heart and circulatory physiology 20010601

Title: Nitric oxide decreases pacemaker activity in lymphatic vessels of guinea pig mesentery.

Journal: American journal of physiology. Heart and circulatory physiology 20010601

Title: L-NAME enhances responses to atrial natriuretic peptide in the pulmonary vascular bed of the cat.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010601

Title: Role of thromboxane in retinal microvascular degeneration in oxygen-induced retinopathy.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010601

Title: Temporal variation in endotoxin-induced vascular hyporeactivity in a rat mesenteric artery organ culture model.

Journal: British journal of pharmacology 20010601

Title: Comparison of the vasoactive effects of the docosanoid unoprostone and selected prostanoids on isolated perfused retinal arterioles.

Journal: Investigative ophthalmology & visual science 20010601

Title: Effects of 8-epi-PGF2alpha on isolated bronchial smooth muscle of healthy and heaves-affected horses.

Journal: Journal of veterinary pharmacology and therapeutics 20010601

Title: Relaxing effects of Ligstrum purpurascens extract and purified acteoside in rat aortic rings.

Journal: Planta medica 20010601

Title: Thromboxane A(2) receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells.

Journal: Biochimica et biophysica acta 20010528

Title: Voltage-dependent Ca2+ release in rat megakaryocytes requires functional IP3 receptors.

Journal: The Journal of physiology 20010515

Title: Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010501

Title: Sites and ionic mechanisms of hypoxic vasoconstriction in frog skin.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010501

Title: The isoprostane 8-iso-PGF(2alpha) stimulates endothelial cells to bind monocytes: differences from thromboxane-mediated endothelial activation.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010501

Title: Inhibitory effects of TA-993 and its metabolite MB3 on platelet activation induced by collagen and U-46619 in human platelets.

Journal: Biological & pharmaceutical bulletin 20010501

Title: Vasorelaxing effect of the potassium (K+)-channel opener pinacidil in isolated porcine ciliary arteries.

Journal: Klinische Monatsblatter fur Augenheilkunde 20010501

Title: L-NAME- and U 46619-induced contractions in isolated porcine ciliary arteries versus vortex veins.

Journal: Klinische Monatsblatter fur Augenheilkunde 20010501

Title: Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010401

Title: Evidence for a non-adrenoceptor, imidazoline-mediated contractile response to oxymetazoline in the porcine isolated rectal artery.

Journal: British journal of pharmacology 20010401

Title: Inhibition of platelet activation in stroke-prone spontaneously hypertensive rats: comparison of losartan, candesartan, and valsartan.

Journal: Journal of cardiovascular pharmacology 20010401

Title: Role of sex differences and effects of endothelial NO synthase deficiency in responses of carotid arteries to serotonin.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20010401

Title: Characterization of the effects of isoprostanes on platelet aggregation in human whole blood.

Journal: British journal of pharmacology 20010401

Title: Mechanisms underlying increased release of endothelin-1 from aorta in diabetic rats.

Journal: Peptides 20010401

Title: Differential involvement of the P2Y1 and P2YT receptors in the morphological changes of platelet aggregation.

Journal: Thrombosis and haemostasis 20010401

Title: Effect of 8-iso-prostaglandin F(2 alpha) on acetylcholine release from parasympathetic nerves in guinea pig airways.

Journal: European journal of pharmacology 20010330

Title: Amplification effect and mechanism of action of ET-1 in U-46619-induced vasoconstriction in pig skin.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Title: Endothelium-independent, ouabain-sensitive relaxation of bovine coronary arteries by EETs.

Journal: American journal of physiology. Heart and circulatory physiology 20010301

Title: Mechanism of CGRP-induced relaxation in rat intramural coronary arteries.

Journal: British journal of pharmacology 20010301

Title: Disturbance of peristalsis in the guinea-pig isolated small intestine by indomethacin, but not cyclo-oxygenase isoform-selective inhibitors.

Journal: British journal of pharmacology 20010301

Title: Developmental changes in reactivity of small femoral arteries in the fetal and postnatal baboon.

Journal: American journal of obstetrics and gynecology 20010301

Title: Inositolphosphate formation in thoracic and abdominal rat aorta following Gq/11-coupled receptor stimulation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010301

Title: L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.

Journal: Journal of hypertension 20010301

Title: Comparison of pulmonary vascular function and structure in early and established hypoxic pulmonary hypertension in rats.

Journal: Canadian journal of physiology and pharmacology 20010301

Title: Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel.

Journal: Platelets 20010301

Title: The angiotensin II AT1 receptor antagonist irbesartan prevents thromboxane A2-induced vasoconstriction in the rat hind-limb vascular bed in vivo.

Journal: Journal of hypertension 20010301

Title: Comparative effects of beraprost, a stable analogue of prostacyclin, with PGE(1), nitroglycerin and nifedipine on canine model of vasoconstrictive pulmonary hypertension.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010301

Title: Thromboxane A(2) causes retarded clearance of aggregated protein in glomeruli of nephritic mice.

Journal: European journal of pharmacology 20010216

Title: Nitric oxide-mediated arteriolar dilation after endothelial deformation.

Journal: American journal of physiology. Heart and circulatory physiology 20010201

Title: Role of endothelial Ni(2+)-sensitive Ca(2+) entry pathway in regulation of EDHF in porcine coronary artery.

Journal: American journal of physiology. Heart and circulatory physiology 20010201

Title: Inhibitory effect of valves on endothelium-dependent relaxations to calcium ionophore in canine saphenous vein.

Journal: American journal of physiology. Heart and circulatory physiology 20010201

Title: Evidence for platelet alphaIIb beta3 activation despite elevated cytosolic cAMP.

Journal: Thrombosis and haemostasis 20010201

Title: Potentiation of thromboxane A2-induced platelet secretion by Gi signaling through the phosphoinositide-3 kinase pathway.

Journal: Thrombosis and haemostasis 20010201

Title: Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries.

Journal: Circulation research 20010119

Title: Melatonin potentiates contractile responses to serotonin in isolated porcine coronary arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: Necessity of thromboxane A2 for initiation of platelet-mediated contact sensitivity: dual activation of platelets and vascular endothelial cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101

Title: Effects of PKC isozyme inhibitors on constrictor responses in the feline pulmonary vascular bed.

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Tags:56985-40-1 Molecular Formula|56985-40-1 MDL|56985-40-1 SMILES|56985-40-1 U-46619