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57046-73-8,MFCD00617529
Catalog No.:AA00EGJW

57046-73-8 | Paprotrain

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$80.00   $56.00
- +
10mg
≥95%
in stock  
$112.00   $78.00
- +
25mg
98% by HPLC
in stock  
$255.00   $179.00
- +
50mg
98% by HPLC
in stock  
$390.00   $273.00
- +
100mg
98% by HPLC
in stock  
$627.00   $439.00
- +
500mg
98% by HPLC
in stock  
$1,882.00   $1,317.00
- +
1000mg
98% by HPLC
in stock  
$2,972.00   $2,081.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EGJW
Chemical Name:
Paprotrain
CAS Number:
57046-73-8
Molecular Formula:
C16H11N3
Molecular Weight:
245.2786
MDL Number:
MFCD00617529
SMILES:
N#C/C(=C\c1cccnc1)/c1c[nH]c2c1cccc2
Properties
Computed Properties
 
Complexity:
392  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.8  

Literature

Title: Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor.

Journal: Angewandte Chemie (International ed. in English) 20101025

Title: Labrière C, et al. Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors. Eur J Med Chem. 2016 Nov 29;124:920-934.

Title: Liu J, et al. MKlp2 inhibitor paprotrain affects polar body extrusion during mouse oocyte maturation. Reprod Biol Endocrinol. 2013 Dec 21;11:117.

Title: Zhang Y, et al. KIF20A regulates porcine oocyte maturation and early embryo development.

Title: Tcherniuk S, et al. Relocation of Aurora B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor. Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8228-31.

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