Home Other Building Blocks 57186-25-1
57186-25-1,MFCD00083464
Catalog No.:AA00E9IW

57186-25-1 | PAXILLINE

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$65.00   $45.00
- +
5mg
≥98%
in stock  
$173.00   $121.00
- +
10mg
≥98%
in stock  
$315.00   $220.00
- +
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Technical Information
Catalog Number:
AA00E9IW
Chemical Name:
PAXILLINE
CAS Number:
57186-25-1
Molecular Formula:
C27H33NO4
Molecular Weight:
435.5552
MDL Number:
MFCD00083464
SMILES:
O=C1C=C2[C@@H](O[C@@H]1C(O)(C)C)CC[C@]1([C@@]2(O)CC[C@@H]2[C@]1(C)c1[nH]c3c(c1C2)cccc3)C C27H33NO4
Properties

Literature

Title: Zhou Y, et al. Paxilline inhibits BK channels by an almost exclusively closed-channel block mechanism. J Gen Physiol. 2014 Nov;144(5):415-40.

Title: Bilmen JG, et al. The mechanism of inhibition of the sarco/endoplasmic reticulum Ca2+ ATPase by paxilline. Arch Biochem Biophys. 2002 Oct 1;406(1):55-64.

Title: Sheehan JJ, et al. Anticonvulsant effects of the BK-channel antagonist paxilline. Epilepsia. 2009 Apr;50(4):711-20.

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