Name: Name:t-Butyl piperazine-1-carboxylate
Brand: AABLOCKS
SKU: AA0035K2
Rating: 90 (10 reviews)

1-Boc-piperazine is utilized in Buchwald-Hartwig amination reactions with aryl halides, yielding various amine derivatives. It serves as a key intermediate in the synthesis of monosubstituted piperazine compounds found in bioactive molecules and drugs like trazodone.

Catalog No.: AA0035K2

57260-71-6 | t-Butyl piperazine-1-carboxylate

Pack Size： 5g

Purity： 99%

in stock

$5.00 $3.00

Pack Size： 10g

Purity： 99%

in stock

$6.00 $4.00

Pack Size： 25g

Purity： 99%

in stock

$8.00 $5.00

Pack Size： 100g

Purity： 99%

in stock

$18.00 $12.00

Pack Size： 250g

Purity： 99%

in stock

$43.00 $30.00

Pack Size： 500g

Purity： 99%

in stock

$80.00 $56.00

Pack Size： 1kg

Purity： 99%

in stock

$140.00 $98.00

Quantity

- +

Add to Card

Order Now

bulk Quotation Request

Technical Information

Catalog Number: AA0035K2

Chemical Name: t-Butyl piperazine-1-carboxylate

CAS Number: 57260-71-6

Molecular Formula: C9H18N2O2

Molecular Weight: 186.2514

MDL Number: MFCD00075265

SMILES: O=C(N1CCNCC1)OC(C)(C)C

Properties

BP: 98-100

Form: Solid

MP: 43-47 °C(lit.)

Stability: Air Sensitive

Storage: Room Temperature;

Complexity: 181

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 13

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0.5

265:

Literature fold

Title: Photoaddition of N-substituted piperazines to C60: an efficient approach to the synthesis of water-soluble fullerene derivatives.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20060717

Title: Ruthenium-catalyzed anti-Markovnikov hydroamination of vinylarenes.

Journal: Journal of the American Chemical Society20040310

Title: Intermolecular, markovnikov hydroamination of vinylarenes with alkylamines.

Journal: Journal of the American Chemical Society20031126

Title: Rhodium-catalyzed anti-Markovnikov hydroamination of vinylarenes.

Journal: Journal of the American Chemical Society20030514

Title: Progress in arylpiperazine synthesis by the catalytic amination reaction.

Journal: Bioorganic & medicinal chemistry20021201

Title: Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

Application fold

1-Boc-piperazine is utilized in Buchwald-Hartwig amination reactions with aryl halides, yielding various amine derivatives. It serves as a key intermediate in the synthesis of monosubstituted piperazine compounds found in bioactive molecules and drugs like trazodone.