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57378-70-8,MFCD00005541
Catalog No.:AA00EPF9

57378-70-8 | 5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid

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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EPF9
Chemical Name:
5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid
CAS Number:
57378-70-8
MDL Number:
MFCD00005541
SMILES:
OC(=O)CCCCC1SCC2C1NC(=O)N2
Properties
Computed Properties
 
Complexity:
298  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
3  
XLogP3:
0.3  

Literature

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Journal: Journal of biomedicine & biotechnology 20120101

Title: Engineered Trx2p industrial yeast strain protects glycolysis and fermentation proteins from oxidative carbonylation during biomass propagation.

Journal: Microbial cell factories 20120101

Title: Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor.

Journal: PloS one 20120101

Title: Plasmonic molecular nanohybrids-spectral dependence of fluorescence quenching.

Journal: International journal of molecular sciences 20120101

Title: Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway.

Journal: Microbial cell factories 20120101

Title: Rapid identification of bio-molecules applied for detection of biosecurity agents using rolling circle amplification.

Journal: PloS one 20120101

Title: Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine.

Journal: BMC microbiology 20120101

Title: Cellular-based immunotherapies for patients with glioblastoma multiforme.

Journal: Clinical & developmental immunology 20120101

Title: Polar extracts from (Tunisian) Acacia salicina Lindl. Study of the antimicrobial and antigenotoxic activities.

Journal: BMC complementary and alternative medicine 20120101

Title: CD8 T-cell induction against vascular endothelial growth factor receptor 2 by Salmonella for vaccination purposes against a murine melanoma.

Journal: PloS one 20120101

Title: Immunoregulatory mechanisms underlying prevention of colitis-associated colorectal cancer by probiotic bacteria.

Journal: PloS one 20120101

Title: Novel serial positive enrichment technology enables clinical multiparameter cell sorting.

Journal: PloS one 20120101

Title: Assessment of Pseudomonas aeruginosa N5,N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase as a potential antibacterial drug target.

Journal: PloS one 20120101

Title: Structure of bradavidin-C-terminal residues act as intrinsic ligands.

Journal: PloS one 20120101

Title: Respiratory membrane endo-hydrogenase activity in the microaerophile Azorhizobium caulinodans is bidirectional.

Journal: PloS one 20120101

Title: Translational control through eIF2alpha phosphorylation during the Leishmania differentiation process.

Journal: PloS one 20120101

Title: Contributions of the peroxisome and β-oxidation cycle to biotin synthesis in fungi.

Journal: The Journal of biological chemistry 20111209

Title: A pre-targeting strategy for MR imaging of functional molecules using dendritic Gd-based contrast agents.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20111201

Title: Therapeutic enhancement of protective immunity during experimental leishmaniasis.

Journal: PLoS neglected tropical diseases 20110901

Title: Photocleavage of avidin by a new pyrenyl probe.

Journal: Journal of photochemistry and photobiology. B, Biology 20110602

Title: Bifunctional avidin with covalently modifiable ligand binding site.

Journal: PloS one 20110101

Title: Expanding the versatility of phage display I: efficient display of peptide-tags on protein VII of the filamentous phage.

Journal: PloS one 20110101

Title: Effects of altered maternal folic acid, vitamin B12 and docosahexaenoic acid on placental global DNA methylation patterns in Wistar rats.

Journal: PloS one 20110101

Title: Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination.

Journal: PloS one 20110101

Title: Human primary adipocytes exhibit immune cell function: adipocytes prime inflammation independent of macrophages.

Journal: PloS one 20110101

Title: Construction of chimeric dual-chain avidin by tandem fusion of the related avidins.

Journal: PloS one 20110101

Title: Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein.

Journal: BMC biotechnology 20110101

Title: Biosensors paving the way to understanding the interaction between cadmium and the estrogen receptor alpha.

Journal: PloS one 20110101

Title: ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing.

Journal: PloS one 20110101

Title: Relative quantification of protein-protein interactions using a dual luciferase reporter pull-down assay system.

Journal: PloS one 20110101

Title: Site directed biotinylation of filamentous phage structural proteins.

Journal: Virology journal 20110101

Title: Vaccination of lactating dairy cows for the prevention of aflatoxin B1 carry over in milk.

Journal: PloS one 20110101

Title: An efficient vector system to modify cells genetically.

Journal: PloS one 20110101

Title: Cardiac ischemia and ischemia/reperfusion cause wide proteolysis of the coronary endothelial luminal membrane: possible dysfunctions.

Journal: The open cardiovascular medicine journal 20110101

Title: Srebf1a is a key regulator of transcriptional control for adipogenesis.

Journal: Scientific reports 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: In situ immobilization of palladium nanoparticles in microfluidic reactors and assessment of their catalytic activity.

Journal: Nanotechnology 20100813

Title: Synthesis of a new NIR fluorescent Nd complex labeling agent.

Journal: Journal of fluorescence 20100101

Title: Experimental evolution of a plant pathogen into a legume symbiont.

Journal: PLoS biology 20100101

Title: Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass.

Journal: Microbial cell factories 20100101

Title: Impact of dietary protein on lipid metabolism-related gene expression in porcine adipose tissue.

Journal: Nutrition & metabolism 20100101

Title: A common carcinogen benzo[a]pyrene causes neuronal death in mouse via microglial activation.

Journal: PloS one 20100101

Title: A vertebrate-specific Chp-PAK-PIX pathway maintains E-cadherin at adherens junctions during zebrafish epiboly.

Journal: PloS one 20100101

Title: Effect of dietary supplementation of organic acids on performance, intestinal histomorphology, and serum biochemistry of broiler chicken.

Journal: Veterinary medicine international 20100101

Title: Asn and asn: critical residues for in vitro biological activity of reteplase.

Journal: Advances in hematology 20100101

Title: Antioxidant and hepatic protective effects of lotus root hot water extract with taurine supplementation in rats fed a high fat diet.

Journal: Journal of biomedical science 20100101

Title: Antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet.

Journal: Journal of biomedical science 20100101

Title: Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease.

Journal: BMC neuroscience 20100101

Title: [Fast separation and analysis of water-soluble vitamins in spinach by capillary electrophoresis with high voltage].

Journal: Se pu = Chinese journal of chromatography 20091101

Title: Effect of supplementing zinc oxide and biotin with or without carbadox on nursery pig performance.

Journal: Journal of animal science 20091001

Title: Identification and characterization of acetyl-CoA carboxylase gene cluster in Streptomyces toxytricini.

Journal: Journal of microbiology (Seoul, Korea) 20090801

Title: Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield.

Journal: Microbial cell factories 20090101

Title: In vivo assessment of zinc deficiency on craniofacial growth in a rat model.

Journal: European journal of dentistry 20090101

Title: Ciliary neurotrophic factor (CNTF) plus soluble CNTF receptor alpha increases cyclooxygenase-2 expression, PGE2 release and interferon-gamma-induced CD40 in murine microglia.

Journal: Journal of neuroinflammation 20090101

Title: Thrombin increases inflammatory cytokine and angiogenic growth factor secretion in human adipose cells in vitro.

Journal: Journal of inflammation (London, England) 20090101

Title: Functional recombinant MHC class II molecules and high-throughput peptide-binding assays.

Journal: Immunome research 20090101

Title: KCNE1 and KCNE3 beta-subunits regulate membrane surface expression of Kv12.2 K(+) channels in vitro and form a tripartite complex in vivo.

Journal: PloS one 20090101

Title: DR*W201/P65 tetramer visualization of epitope-specific CD4 T-cell during M. tuberculosis infection and its resting memory pool after BCG vaccination.

Journal: PloS one 20090101

Title: Structural and functional characteristics of xenavidin, the first frog avidin from Xenopus tropicalis.

Journal: BMC structural biology 20090101

Title: Preparation of rat brain aggregate cultures for neuron and glia development studies.

Journal: Journal of visualized experiments : JoVE 20090101

Title: The effect of seamustard on blood lipid profiles and glucose level of rats fed diet with different energy composition.

Journal: Nutrition research and practice 20090101

Title: Why 1-NH and 3-NH protons of D-biotin exhibit different activities in aqueous solution.

Journal: The journal of physical chemistry. B 20080724

Title: Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations.

Journal: Journal of medical genetics 20080601

Title: Comparative study of the antimutagenic properties of vitamins C and E against mutation induced by norfloxacin.

Journal: BMC pharmacology 20080101

Title: Application of biotin-4-fluorescein in homogeneous fluorescence assays for avidin, streptavidin, and biotin or biotin derivatives.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis.

Journal: PloS one 20080101

Title: Effect of Chlorella vulgaris on lipid metabolism in Wistar rats fed high fat diet.

Journal: Nutrition research and practice 20080101

Title: Effect of biotin supplementation on meat quality of F1 Wagyu/Black Angus feedlot steers of known genotype.

Journal: Meat science 20071001

Title: Microwave-accelerated ultrafast nanoparticle aggregation assays using gold colloids.

Journal: Analytical chemistry 20070301

Title: Structure and characterization of a novel chicken biotin-binding protein A (BBP-A).

Journal: BMC structural biology 20070101

Title: Effect of L-carnitine on skeletal muscle lipids and oxidative stress in rats fed high-fructose diet.

Journal: Experimental diabetes research 20070101

Title: Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats.

Journal: Nutrition research and practice 20070101

Title: Binding properties of HABA-type azo derivatives to avidin and avidin-related protein 4.

Journal: Chemistry & biology 20061001

Title: Controlling quaternary structure assembly: subunit interface engineering and crystal structure of dual chain avidin.

Journal: Journal of molecular biology 20060623

Title: Oestrogen receptor beta and neoadjuvant therapy with tamoxifen: prediction of response and effects of treatment.

Journal: British journal of cancer 20060508

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Effect of microsphere binding site density on the apparent affinity of an interaction partner.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Synthesis of a biotin-derived alkyne for pd-catalyzed coupling reactions.

Journal: Organic letters 20060427

Title: A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens.

Journal: Journal of immune based therapies and vaccines 20060101

Title: Bioconjugated superstructures of CdTe nanowires and nanoparticles: multistep cascade Förster resonance energy transfer and energy channeling.

Journal: Nano letters 20051001

Title: Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs.

Journal: PLoS medicine 20051001

Title: Synthetic studies on d-biotin, part 9. An improved asymmetric synthetic route to d-biotin via Hoffmann-Roche lactone-thiolactone approach.

Journal: Chemical & pharmaceutical bulletin 20050701

Title: Effects of vitamin-B complex supplementation on periodontal wound healing.

Journal: Journal of periodontology 20050701

Title: Avidin related protein 2 shows unique structural and functional features among the avidin protein family.

Journal: BMC biotechnology 20050101

Title: Dietary inulin intake and age can significantly affect intestinal absorption of calcium and magnesium in rats: a stable isotope approach.

Journal: Nutrition journal 20050101

Title: Single-step purification of full-length human androgen receptor.

Journal: Nuclear receptor signaling 20050101

Title: Soluble expression of aggregating proteins by covalent coupling to the ribosome.

Journal: Biochemical and biophysical research communications 20040702

Title: In vivo biotinylation of the major histocompatibility complex (MHC) class II/peptide complex by coexpression of BirA enzyme for the generation of MHC class II/tetramers.

Journal: Human immunology 20040701

Title: Quenched emission of fluorescence by ligand functionalized gold nanoparticles.

Journal: Journal of fluorescence 20040701

Title: Dual-polarization interferometry: an analytical technique to measure changes in protein structure in real time, to determine the stoichiometry of binding events, and to differentiate between specific and nonspecific interactions.

Journal: Analytical biochemistry 20040615

Title: Experimental evidence for the existence of the passive antitumor defense system formed by the synergistic action of certain small substances of the circulatory system.

Journal: Cancer biotherapy & radiopharmaceuticals 20031201

Title: Carnitine profiles during differentiation and effects of carnitine on differentiation of 3T3-L1 cells.

Journal: Journal of medicinal food 20030101

Title: Supramolecular DNA-streptavidin nanocircles with a covalently attached oligonucleotide moiety.

Journal: Journal of biomolecular structure & dynamics 20021001

Title: Expression of oestrogen receptor beta (ERbeta1) protein in human breast cancer biopsies.

Journal: British journal of cancer 20020121

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SDS
Tags:57378-70-8 Molecular Formula|57378-70-8 MDL|57378-70-8 SMILES|57378-70-8 5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid