Name: Name:2-(4-Chlorophenyl)acetohydrazide
Brand: AABLOCKS
SKU: AA00E96Z
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00E96Z

Chemical Name: 2-(4-Chlorophenyl)acetohydrazide

CAS Number: 57676-51-4

Molecular Formula: C8H9ClN2O

Molecular Weight: 184.6229

MDL Number: MFCD00157887

SMILES: NNC(=O)Cc1ccc(cc1)Cl

Properties

BP: 394.9°C at 760 mmHg

Storage: Keep in dry area;2-8℃;

Complexity: 155

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 12

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.1

Downstream Synthesis Route

75-44-5

57676-51-4

34547-04-1

[1]Rosen,G.M.etal.[JournalofHeterocyclicChemistry,1971,vol.8,p.659-662]

52449-43-1

57676-51-4

[1]ZeitschriftfurChemie,1989,vol.29,p.283-284

[2]JournalofAgriculturalandFoodChemistry,2012,vol.60,p.1036-1041

[3]Arzneimittel-Forschung/DrugResearch,2011,vol.61,p.452-457

[4]BioorganicandMedicinalChemistryLetters,2014,vol.24,p.1677-1680

[5]Phosphorus,SulfurandSiliconandtheRelatedElements,2016,vol.191,p.904-907

[6]JournalofHeterocyclicChemistry,2019,vol.56,p.1376-1382

67-56-1

57676-51-4

52449-43-1

[1]JournalofChemicalResearch-PartS,2000,p.376-377

1878-66-6

57676-51-4

[1]Chaudhary,BharatN.;Gandhi,Bhumi;Kanhed,AshishM.;Patel,DushyantV.;Patel,KirtiV.;Patel,KishanB.;Patel,NiravR.;Prajapati,NavnitK.;Shah,BhavikS.;Teli,DivyaM.;Yadav,MangeRam[JournalofBiomolecularStructureandDynamics,2021]

[2]Xu,Wei-Ming;Han,Fei-Fei;He,Ming;Hu,De-Yu;He,Jiang;Yang,Song;Song,Bao-An[JournalofAgriculturalandFoodChemistry,2012,vol.60,#4,p.1036-1041]

[3]Chhabria,MaheshT.;Suhagia,BhanubhaiN.;Brahmkshatriya,PathikS.;Raval,PriyeshaM.[Arzneimittel-Forschung/DrugResearch,2011,vol.61,#8,p.452-457]

[4]Kaushik,Darpan;Kumar,Rajnish;Khan,SuroorAhmed;Chawla,Gita[MedicinalChemistryResearch,2012,vol.21,#11,p.3646-3655]

[5]Li,Pei;Shi,Li;Yang,Xia;Yang,Lei;Chen,Xue-Wen;Wu,Fang;Shi,Qing-Cai;Xu,Wei-Ming;He,Ming;Hu,De-Yu;Song,Bao-An[BioorganicandMedicinalChemistryLetters,2014,vol.24,#7,p.1677-1680]

[6]Li,Pei;Shi,Li;Gao,Man-Ni;Yang,Xia;Xue,Wei;Jin,Lin-Hong;Hu,De-Yu;Song,Bao-An[BioorganicandMedicinalChemistryLetters,2015,vol.25,#3,p.481-484]

[7]Chen,Ling;Wang,Peiyi;Li,Zhenxing;Zhou,Lei;Wu,Zhibing;Song,Baoan;Yang,Song[ChineseJournalofChemistry,2016,vol.34,#12,p.1236-1244]

[8]Zhou,Wen-Juan;Zhang,Li;Xiao,Wei;Chen,He-Ju;Wu,Wen-Neng;Ouyang,Gui-Ping[JournalofHeterocyclicChemistry,2017,vol.54,#2,p.1423-1429]

[9]CurrentPatentAssignee:SOUTHERNILLINOISUNIVERSITY-WO2018/209267,2018,A2

[10]Kamboj,VipanKumar;Kapoor,Archana;Jain,Sandeep[JournalofHeterocyclicChemistry,2019,vol.56,#4,p.1376-1382]

[11]Wang,Xiaobin;Chai,Jianqi;Kong,Xiangyi;Jin,Fei;Chen,Min;Yang,Chunlong;Xue,Wei[BioorganicandMedicinalChemistry,2021,vol.45]

[12]Crider,A.Michael;Farr,SusanA.;Frare,Rafael;Hospital,Audrey;Kontoyianni,Maria;Kukielski,StephenG.;Minaeian,Mahsa;Mobayen,Shirin;Neumann,WilliamL.;Niehoff,MichaelL.;Sandoval,KarinE.;Slater,Olivia;Srabony,KhushN.;Witt,KenA.[2021,vol.12,#8,p.1352-1365]

[13]Zhu,Jian-Jun;Wang,Pei-Yi;Long,Zhou-Qing;Xiang,Shu-Zhen;Zhang,Jun-Rong;Li,Zhen-Xing;Wu,Yuan-Yuan;Shao,Wu-Bin;Zhou,Xiang;Liu,Li-Wei;Yang,Song[JournalofAgriculturalandFoodChemistry,2022,vol.70,#9,p.2825-2838]

57676-51-4

14527-26-5

501919-85-3

[1]EuropeanJournalofMedicinalChemistry,2013,vol.67,p.325-334

Literature fold

Title: Rational design of new antituberculosis agents: receptor-independent four-dimensional quantitative structure-activity relationship analysis of a set of isoniazid derivatives.

Journal: Journal of medicinal chemistry20040715

Title: Chemotherapy of experimental tuberculosis. V. Isonicotinic acid hydrazide (nydrazid) and related compounds.

Journal: American review of tuberculosis19520401

57676-51-4 | 2-(4-Chlorophenyl)acetohydrazide