Home Fluorides 579-39-5
579-39-5,MFCD00134541
Catalog No.:AA003KCE

579-39-5 | 4,4'-Difluorobenzil

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1g
98%
in stock  
$7.00   $5.00
- +
5g
98%
in stock  
$19.00   $14.00
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10g
98%
in stock  
$37.00   $26.00
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25g
98%
in stock  
$87.00   $61.00
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100g
98%
in stock  
$251.00   $176.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003KCE
Chemical Name:
4,4'-Difluorobenzil
CAS Number:
579-39-5
Molecular Formula:
C14H8F2O2
Molecular Weight:
246.2089
MDL Number:
MFCD00134541
SMILES:
O=C(C(=O)c1ccc(cc1)F)c1ccc(cc1)F
Properties
Properties
 
BP:
370.2 °C at 760 mmHg  
Form:
Solid  
MP:
120-122 °C(lit.);  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
282  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
3.6  

Downstream Synthesis Route

[1]JournalofOrganicChemistry,1995,vol.60,p.5016-5023

[1]BioorganicandMedicinalChemistryLetters,2000,vol.10,p.2603-2605

[1]BioorganicandMedicinalChemistry,2007,vol.15,p.3801-3817

[2]Macromolecules,2005,vol.38,p.297-306

[3]Patent:CN106916113,2017,A.Locationinpatent:Paragraph0016;0022;0024

[4]Molecularcatalysis,2018,vol.454,p.63-69

[5]OrganicLetters,2012,vol.14,p.4906-4909,4

[6]Patent:WO2004/52857,2004,A1.Locationinpatent:Page76

[7]Patent:WO2004/69835,2004,A1.Locationinpatent:Page17

[8]OrganicLetters,2003,vol.5,p.3599-3602

[9]JournalofMedicinalChemistry,2005,vol.48,p.7486-7490

[10]Patent:US2007/112061,2007,A1.Locationinpatent:Page/Pagecolumn5

[11]TetrahedronLetters,2013,vol.54,p.231-234

[12]BioorganicandMedicinalChemistryLetters,2016,vol.26,p.2806-2809

[13]GreenChemistry,2016,vol.18,p.3647-3655

[14]AngewandteChemie-InternationalEdition,2018,vol.57,p.12318-12322    Angew.Chem.,2018,vol.130,p.12498-12502,5

78637-85-1    579-39-5   
2,3-bis(4-fluorophenyl)thieno3,4-bpyrazine 

[1]TetrahedronLetters,2004,vol.45,p.4873-4876

579-39-5    496-72-0   
2,3-bis(4-fluoro-phenyl)-6-methylquinoxaline 

[1]Heravi,MajidM.;Bakhtiari,Khadijeh;Bamoharram,FatemehF.;Tehrani,MaryamH.[MonatsheftefurChemie,2007,vol.138,#5,p.465-467]

[2]Locationinpatent:experimentalpartMirjalili;Bamoniri;Akbari[ChemistryofHeterocyclicCompounds,2011,vol.47,#4,p.487-491]

[3]Chandrachood,PranavS.;Jadhav,AmolR.;Garud,DineshR.;Deshpande,NirmalaR.;Puranik,VedavatiG.;Kashalkar,RajashreeV.[ResearchonChemicalIntermediates,2020,vol.46,#12,p.5219-5230]

[4]Langer,Peter;Luque,Rafael;Palermo,Valeria;Pizzio,LuisR.;Romanelli,GustavoP.;Sosa,AlexisA.[Molecularcatalysis,2022,vol.517]

[5]Vahdat,SeyedMohammad;Baghery,Saeed[CombinatorialChemistryandHighThroughputScreening,2013,vol.16,#8,p.618-627]

[6]Javidi,Jaber;Esmaeilpour,Mohsen[MaterialsResearchBulletin,2016,vol.73,p.409-422]

[7]Daragahi,SeyedArashHosseini;Mohebat,Razieh;Mosslemin,MohammadHossein[OrganicPreparationsandProceduresInternational,2018,vol.50,#3,p.301-313]

[8]Locationinpatent:experimentalpartZare,Abdolkarim;Hasaninejad,Alireza;Parhami,Abolfath;Moosavi-Zare,AhmadReza;Khedri,Fatemeh;Parsaee,Zahra;Abdolalipoor-Saretoli,Maasoomeh;Khedri,Maasoomeh;Roshankar,Mehrnoosh;Deisi,Hanafieh[JournaloftheSerbianChemicalSociety,2010,vol.75,#10,p.1315-1324]

[9]Locationinpatent:experimentalpartKarami,Bahador;Khodabakhshi,Saeed[JournaloftheSerbianChemicalSociety,2011,vol.76,#9,p.1191-1198]

[10]Rajabi,Fatemeh;Alves,Diego;Luque,Rafael[Molecules,2015,vol.20,#11,p.20709-20718]

[11]Locationinpatent:experimentalpartHasaninejad,Alireza;Zare,Abdolkarim;Zolfigol,MohammadAli;Shekouhy,Mohsen[SyntheticCommunications,2009,vol.39,#4,p.569-579]

[12]Locationinpatent:experimentalpartKidwai,Mazaahir;Mishra,NeerajKumar;Bhatnagar,Divya;Jahan,Anwar[AsianJournalofChemistry,2011,vol.23,#11,p.5051-5054]

[13]Locationinpatent:experimentalpartMirjalili,BiBiFatemeh;Akbari,Ali[ChineseChemicalLetters,2011,vol.22,#6,p.753-756]

[14]Locationinpatent:experimentalpartKarami,Bahador;Khodabakhshi,Saeed;Nikrooz,Marzieh[JournaloftheChineseChemicalSociety,2012,vol.59,#2,p.187-192]

[15]Karami,Bahador;Khodabakhshi,Saeed[JournaloftheChileanChemicalSociety,2013,vol.58,#2,p.1655-1658]

[16]Keshtov;Keshtova;Begretov;Tkhakakhov[RussianJournalofGeneralChemistry,2003,vol.73,#9,p.1476-1480]

[17]Locationinpatent:experimentalpartKarami,Bahador;Rooydel,Reza;Khodabakhshi,Saeed[ActaChimicaSlovenica,2012,vol.59,#1,p.183-188]

Literature

Title: Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis.

Journal: Bioorganic & medicinal chemistry 20090101

Title: (E)-1,2-Bis(4-fluoro-phen-yl)ethane-1,2-dione.

Journal: Acta crystallographica. Section E, Structure reports online 20080801

Title: Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils.

Journal: Bioorganic & medicinal chemistry 20070601

Title: Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

Journal: Journal of medicinal chemistry 20050421

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Tags:579-39-5 Molecular Formula|579-39-5 MDL|579-39-5 SMILES|579-39-5 4,4'-Difluorobenzil |Fluorinated_Building_Blocks