[1]ZhurnalRusskagoFiziko-KhimicheskagoObshchestva,1920,vol.50,p.554 ChemischesZentralblatt,1923,vol.94,p.1023
[1]Tetrahedron,1987,vol.43,p.4931-4946
[2]SyntheticCommunications,1991,vol.21,p.1841-1846
[3]OrganicLetters,2013,vol.15,p.3734-3737
[4]Heterocycles,1980,vol.14,p.287-290
[5]JournalfurpraktischeChemie(Leipzig1954),1897,vol.<2>56,p.206
[6]JournalfurpraktischeChemie(Leipzig1954),1923,vol.<2>106,p.63
[7]ChemischeBerichte,1900,vol.33,p.1885
[8]ChemischeBerichte,1900,vol.33,p.1885
[1]BioorganicandMedicinalChemistryLetters,2016,vol.26,p.512-517
[2]JournalofOrganicChemistry,1959,vol.24,p.374,380
[1]JournaloftheAmericanChemicalSociety,1958,vol.80,p.3066,3067
[1]JournaloftheAmericanChemicalSociety,1947,vol.69,p.1393,1394,1400
Title: Lys05: a new lysosomal autophagy inhibitor.
Journal: Autophagy 20120901
Title: Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides.
Journal: Biological chemistry 20120801
Title: One-pot synthesis of 2-aminoquinoline-based alkaloids from acetonitrile.
Journal: Organic & biomolecular chemistry 20120714
Title: Synthesis of aminoquinoline-based aminoalcohols and oxazolidinones and their antiplasmodial activity.
Journal: Chemical biology & drug design 20120301
Title: Proton grease: an acid accelerated molecular rotor.
Journal: Journal of the American Chemical Society 20120227
Title: Reactions of substituted pyridines with electrophilic boranes.
Journal: Dalton transactions (Cambridge, England : 2003) 20120221
Title: Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.
Journal: The Journal of biological chemistry 20120203
Title: Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoni.
Journal: PLoS neglected tropical diseases 20120201
Title: Synthetic peroxides as potent antimalarials. News and views.
Journal: Current topics in medicinal chemistry 20120101
Title: Novel binding mode of a potent and selective tankyrase inhibitor.
Journal: PloS one 20120101
Title: Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites.
Journal: PloS one 20120101
Title: A chelation enhanced selective fluorescence sensing of Hg2+ by a simple quinoline substituted tripodal amide receptor.
Journal: Dalton transactions (Cambridge, England : 2003) 20111214
Title: Highly effective therapy for maternal malaria associated with a lower risk of vertical transmission.
Journal: The Journal of infectious diseases 20111115
Title: Comprehensive profiling and quantitation of amine group containing metabolites.
Journal: Analytical chemistry 20111001
Title: From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1).
Journal: Journal of medicinal chemistry 20110825
Title: A residue W756 in the P-loop segment of the sodium channel is critical for primaquine binding.
Journal: European journal of pharmacology 20110801
Title: Palladium(II) complexes of quinolinylaminophosphonates: synthesis, structural characterization, antitumor and antimicrobial activity.
Journal: Journal of inorganic biochemistry 20110601
Title: {N,N'-[2,2'-(Ethane-1,2-diyldisulfanediyl)di-o-phenyl-ene]bis-(quinoline-2-carboxamidato)}copper(II).
Journal: Acta crystallographica. Section E, Structure reports online 20110601
Title: Clinical and Rehabilitative Management of Retinitis Pigmentosa: Up-to-Date.
Journal: Current genomics 20110601
Title: Highly sensitive MALDI analyses of glycans by a new aminoquinoline-labeling method using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid liquid matrix.
Journal: Analytical chemistry 20110515
Title: Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids.
Journal: Bioorganic & medicinal chemistry letters 20110315
Title: Acridine and acridinones: old and new structures with antimalarial activity.
Journal: The open medicinal chemistry journal 20110101
Title: Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations.
Journal: Malaria journal 20110101
Title: PfMDR1: mechanisms of transport modulation by functional polymorphisms.
Journal: PloS one 20110101
Title: Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.
Journal: PloS one 20110101
Title: A girl with cutaneous lesions, polyarthritis, and antinuclear antibodies positivity.
Journal: ISRN dermatology 20110101
Title: Molecular-field-based three-dimensional similarity studies on quinoline-based CNS active agents.
Journal: ISRN pharmaceutics 20110101
Title: Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties.
Journal: Organic & biomolecular chemistry 20101221
Title: Reactivity of the bifunctional ambiphilic molecule 8-(dimesitylboryl)quinoline: hydrolysis and coordination to Cu(I), Ag(I) and Pd(II).
Journal: Dalton transactions (Cambridge, England : 2003) 20101207
Title: Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds.
Journal: Bioorganic & medicinal chemistry 20101201
Title: Synthesis and anti-prion activity evaluation of aminoquinoline analogues.
Journal: European journal of medicinal chemistry 20101101
Title: Synthesis and in vitro antiproliferative activity of 5-alkyl-12(H)-quino[3,4-b] [1,4]benzothiazinium salts.
Journal: European journal of medicinal chemistry 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: N-[(2-Chloro-8-methyl-quinolin-3-yl)meth-yl]-4-meth-oxy-aniline.
Journal: Acta crystallographica. Section E, Structure reports online 20101101
Title: Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase.
Journal: Molecular pharmacology 20101001
Title: Solution behavior of hematin under acidic conditions and implications for its interactions with chloroquine.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100901
Title: Resonance Raman characterization of the different forms of ground-state 8-substituted 7-hydroxyquinoline caged acetate compounds in aqueous solutions.
Journal: The journal of physical chemistry. A 20100225
Title: A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases.
Journal: Cell death & disease 20100201
Title: Screening a mushroom extract library for activity against Acinetobacter baumannii and Burkholderia cepacia and the identification of a compound with anti-Burkholderia activity.
Journal: Annals of clinical microbiology and antimicrobials 20100101
Title: Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors.
Journal: PloS one 20100101
Title: Establishment of an in vitro assay for assessing the effects of drugs on the liver stages of Plasmodium vivax malaria.
Journal: PloS one 20100101
Title: Fluorescent chemosensors for toxic organophosphorus pesticides: a review.
Journal: Sensors (Basel, Switzerland) 20100101
Title: Recent developments in the design and synthesis of hybrid molecules based on aminoquinoline ring and their antiplasmodial evaluation.
Journal: European journal of medicinal chemistry 20090801
Title: Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model.
Journal: Experimental parasitology 20090701
Title: Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists.
Journal: Bioorganic & medicinal chemistry letters 20090701
Title: Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry 20090701
Title: Aminoquinoline derivatives with antiproliferative activity against melanoma cell line.
Journal: Bioorganic & medicinal chemistry letters 20090701
Title: Resistance-mediating polymorphisms in Plasmodium falciparum infections in Kinshasa, Democratic Republic of the Congo.
Journal: The American journal of tropical medicine and hygiene 20090401
Title: Two complementary fluorimetric assays for the determination of aminoquinoline binding and uptake by human erythrocytes in vitro.
Journal: Analytical biochemistry 20090215
Title: Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine.
Journal: Inorganic chemistry 20090202
Title: Malarial parasite pathogenesis and drug targets.
Journal: F1000 biology reports 20090101
Title: Sequential and selective Buchwald-Hartwig amination reactions for the controlled functionalization of 6-bromo-2-chloroquinoline: synthesis of ligands for the Tec Src homology 3 domain.
Journal: The Journal of organic chemistry 20081121
Title: 4-N-, 4-S-, and 4-O-chloroquine analogues: influence of side chain length and quinolyl nitrogen pKa on activity vs chloroquine resistant malaria.
Journal: Journal of medicinal chemistry 20080626
Title: A highly efficient and selective turn-on fluorescent sensor for Cu2+ ion based on calix[4]arene bearing four iminoquinoline subunits on the upper rim.
Journal: Chemical communications (Cambridge, England) 20080421
Title: Determination of oseltamivir quality by colorimetric and liquid chromatographic methods.
Journal: Emerging infectious diseases 20080401
Title: Development of CXCR3 antagonists. Part 4: discovery of 2-amino-(4-tropinyl)quinolines.
Journal: Bioorganic & medicinal chemistry letters 20080115
Title: Hybrid molecules with a dual mode of action: dream or reality?
Journal: Accounts of chemical research 20080101
Title: Metallocene antimalarials: the continuing quest.
Journal: Metal-based drugs 20080101
Title: The prince and the pauper. A tale of anticancer targeted agents.
Journal: Molecular cancer 20080101
Title: Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues.
Journal: Bioorganic & medicinal chemistry letters 20071201
Title: Design, synthesis, and preliminary pharmacological evaluation of new quinoline derivatives as nicotinic ligands.
Journal: Journal of medicinal chemistry 20071004
Title: Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)).
Journal: Bioorganic & medicinal chemistry 20070815
Title: Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists.
Journal: Bioorganic & medicinal chemistry letters 20070801
Title: A Cl- anion-responsive luminescent Eu3+ complex with a chiral tripod: ligand substituent effects on ternary complex stoichiometry and anion sensing selectivity.
Journal: Dalton transactions (Cambridge, England : 2003) 20070714
Title: Picosecond time-resolved fluorescence study on solute-solvent interaction of 2-aminoquinoline in room-temperature ionic liquids: aromaticity of imidazolium-based ionic liquids.
Journal: The journal of physical chemistry. B 20070510
Title: Application of fragment screening by X-ray crystallography to beta-secretase.
Journal: Journal of medicinal chemistry 20070322
Title: Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase.
Journal: Journal of medicinal chemistry 20070322
Title: Quinazoline and benzimidazole MCH-1R antagonists.
Journal: Bioorganic & medicinal chemistry letters 20070301
Title: Crystal and molecular structures of trichloro-cobalt(II) complexes of epiquinine, epiquinidine, and epidihydrocinchonine.
Journal: Chirality 20070201
Title: Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers.
Journal: PLoS clinical trials 20070101
Title: World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria.
Journal: Malaria journal 20070101
Title: Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1-R) antagonists.
Journal: Current topics in medicinal chemistry 20070101
Title: Excited-state proton transfer through water bridges and structure of hydrogen-bonded complexes in 1H-pyrrolo[3,2-h]quinoline: adiabatic time-dependent density functional theory study.
Journal: The journal of physical chemistry. A 20061102
Title: 2-Aminoquinoline melanin-concentrating hormone (MCH)1R antagonists.
Journal: Bioorganic & medicinal chemistry letters 20061015
Title: Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol.
Journal: Bioorganic & medicinal chemistry 20060815
Title: Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.
Journal: Journal of the American Chemical Society 20060809
Title: A dynamic tricopper double helicate.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20060515
Title: Quinolactacins revisited: from lactams to imide and beyond.
Journal: Organic & biomolecular chemistry 20060421
Title: Sensitive fluorescence HPLC assay for AQ-13, a candidate aminoquinoline antimalarial, that also detects chloroquine and N-dealkylated metabolites.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060403
Title: Three 4-aminoquinolines of antimalarial interest.
Journal: Acta crystallographica. Section C, Crystal structure communications 20060201
Title: Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain.
Journal: Bioorganic & medicinal chemistry letters 20060115
Title: Molecular surveillance of mutations in the cytochrome b gene of Plasmodium falciparum in Gabon and Ethiopia.
Journal: Malaria journal 20060101
Title: The use of genotyping in antimalarial clinical trials: a systematic review of published studies from 1995-2005.
Journal: Malaria journal 20060101
Title: Synthesis of C-nucleosides designed to participate in triplex formation with native DNA: specific recognition of an A:T base pair in DNA.
Journal: The Journal of organic chemistry 20051028
Title: Structure-function studies on a synthetic guanosine receptor that simultaneously binds Watson-Crick and Hoogsteen sites.
Journal: The Journal of organic chemistry 20050916
Title: Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands.
Journal: Organic & biomolecular chemistry 20050721
Title: Steric effect on the nuclease activity of Cu(II) complexes with aminoquinoline derivatives.
Journal: Journal of inorganic biochemistry 20050701
Title: Subacute cutaneous lupus erythematosus: 25-year evolution of a prototypic subset (subphenotype) of lupus erythematosus defined by characteristic cutaneous, pathological, immunological, and genetic findings.
Journal: Autoimmunity reviews 20050601
Title: Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase.
Journal: Bioorganic & medicinal chemistry letters 20050415
Title: [Unwanted reactions to modifying antirheumatic drugs].
Journal: Terapevticheskii arkhiv 20050101
Title: Identification and specificity studies of small-molecule ligands for SH3 protein domains.
Journal: Journal of medicinal chemistry 20041021
Title: Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa.
Journal: Journal of the American Society for Mass Spectrometry 20040601
Title: Molecular complexes of IQ and 4-hydroxy-coumarin: a mutagen-anti-mutagen system.
Journal: Journal of photochemistry and photobiology. B, Biology 20040527
Title: Synthesis and antimalarial activity of trioxaquine derivatives.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040402
Title: 4-Aryl(benzyl)amino-4-heteroarylbut-1-enes as building blocks in heterocyclic synthesis. 4. Synthesis of 4, 6-dimethyl-5-nitro(amino)-2-pyridylquinolines and their antiparasitic activities.
Journal: Archiv der Pharmazie 20040301
Title: Antimalarial lichenoid tissue reactions in patients with pre-existing lupus erythematosus.
Journal: Lupus 20040101
Title: Genomics research and malaria control: great expectations.
Journal: PLoS biology 20031101
Title: Synthesis, characterization and antitumor activity of platinum(II) complexes with diethyl and monoethyl 2-quinolylmethylphosphonates.
Journal: Journal of inorganic biochemistry 20030701
Title: Chloroquine and artemisinin: six decades of research--what next?
Journal: IDrugs : the investigational drugs journal 20030701
Title: Electrochemical study of hydroxychloroquine and its determination in plaquenil by differential pulse voltammetry.
Journal: Journal of pharmaceutical and biomedical analysis 20030601
Title: Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities.
Journal: Bioorganic & medicinal chemistry 20030515
Title: Conductometric and indirect AAS determination of antimalarials.
Journal: Journal of pharmaceutical and biomedical analysis 20030326
Title: Severe malaria in a splenectomised Gabonese woman.
Journal: Wiener klinische Wochenschrift 20030131
Title: Novel zinc fluorescent probe bearing dansyl and aminoquinoline groups.
Journal: Chemical communications (Cambridge, England) 20020707
Title: Characterization of a didehydrobenzoxazine intermediate in a novel carbene-to-carbene transformation.
Journal: Journal of the American Chemical Society 20020703
Title: Dermatomyositis: an overview of recent progress with emphasis on dermatologic aspects.
Journal: Dermatologic clinics 20020701
Title: 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates.
Journal: Biochemistry 20020305
Title: Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity.
Journal: Journal of medicinal chemistry 20020227
Title: Dissociation and electrooxidation of primaquine diphosphate as an approach to the study of anti-chagas prodrugs mechanism of action.
Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20010101
Title: Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13.
Journal: Environmental and molecular mutagenesis 20010101