Title: Miltefosine for visceral and cutaneous leishmaniasis: drug characteristics and evidence-based treatment recommendations.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20150501
Title: Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1.
Journal: Antimicrobial agents and chemotherapy 20140801
Title: Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives.
Journal: Journal of medicinal chemistry 20130926
Title: Synthesis and antifungal activities of miltefosine analogs.
Journal: Bioorganic & medicinal chemistry letters 20130901
Title: Synthesis, self-aggregation and biological properties of alkylphosphocholine and alkylphosphohomocholine derivatives of cetyltrimethylammonium bromide, cetylpyridinium bromide, benzalkonium bromide (C16) and benzethonium chloride.
Journal: European journal of medicinal chemistry 20130801
Title: Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives.
Journal: Journal of medicinal chemistry 20130711
Title: Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines.
Journal: Journal of medicinal chemistry 20130227
Title: Effect of alkylphospholipids on Candida albicans biofilm formation and maturation.
Journal: The Journal of antimicrobial chemotherapy 20130101
Title: Nuclease activity and ultrastructural effects of new sulfonamides with anti-leishmanial and trypanocidal activities.
Journal: Parasitology international 20121201
Title: Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships.
Journal: Bioorganic & medicinal chemistry letters 20121115
Title: Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis.
Journal: The Journal of antimicrobial chemotherapy 20121101
Title: Chemotherapy of leishmaniasis. Part IX: synthesis and bioevaluation of aryl substituted ketene dithioacetals as antileishmanial agents.
Journal: Bioorganic & medicinal chemistry letters 20121101
Title: Miltefosine represses HIV-1 replication in human dendritic cell/T-cell cocultures partially by inducing secretion of type-I interferon.
Journal: Virology 20121025
Title: Flavonoid dimers as novel, potent antileishmanial agents.
Journal: Journal of medicinal chemistry 20121025
Title: Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier.
Journal: The American journal of tropical medicine and hygiene 20121003
Title: Combination of paromomycin and miltefosine promotes TLR4-dependent induction of antileishmanial immune response in vitro.
Journal: The Journal of antimicrobial chemotherapy 20121001
Title: 2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani.
Journal: Bioorganic & medicinal chemistry letters 20121001
Title: Oxazolo[3,2-a]pyridine. A new structural scaffold for the reversal of multi-drug resistance in Leishmania.
Journal: Bioorganic & medicinal chemistry letters 20121001
Title: Interaction of miltefosine with intercellular membranes of stratum corneum and biomimetic lipid vesicles.
Journal: International journal of pharmaceutics 20120915
Title: Drug delivery systems for the topical treatment of cutaneous leishmaniasis.
Journal: Expert opinion on drug delivery 20120901
Title: Leishmania mexicana metacaspase is a negative regulator of amastigote proliferation in mammalian cells.
Journal: Cell death & disease 20120901
Title: Defeating Leishmania resistance to miltefosine (hexadecylphosphocholine) by peptide-mediated drug smuggling: a proof of mechanism for trypanosomatid chemotherapy.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120810
Title: Augmentation of antileishmanial efficacy of miltefosine in combination with tuftsin against experimental visceral leishmaniasis.
Journal: Parasitology research 20120801
Title: Efficacy of miltefosine in the treatment of visceral leishmaniasis in India after a decade of use.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120801
Title: Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine.
Journal: The Journal of antimicrobial chemotherapy 20120801
Title: Discovery of a new antileishmanial hit in 8-nitroquinoline series.
Journal: European journal of medicinal chemistry 20120801
Title: Effects of miltefosine on the proliferation, ultrastructure, and phospholipid composition of Angomonas deanei, a trypanosomatid protozoan that harbors a symbiotic bacterium.
Journal: FEMS microbiology letters 20120801
Title: Enhancement in therapeutic efficacy of miltefosine in combination with synthetic bacterial lipopeptide, Pam3Cys against experimental Visceral Leishmaniasis.
Journal: Experimental parasitology 20120701
Title: Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response.
Journal: PLoS neglected tropical diseases 20120701
Title: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization for a lipidomic analysis of Leishmania donovani.
Journal: Journal of chromatography. A 20120615
Title: Synthesis and anti-leishmanial activity of 1-aryl-β-carboline derivatives against Leishmania donovani.
Journal: Bioorganic & medicinal chemistry letters 20120615
Title: Novel 3-nitro-1H-1,2,4-triazole-based amides and sulfonamides as potential antitrypanosomal agents.
Journal: Journal of medicinal chemistry 20120614
Title: Ultrastructural analysis of miltefosine-induced surface membrane damage in adult Schistosoma mansoni BH strain worms.
Journal: Parasitology research 20120601
Title: Canine leishmaniosis: in vitro efficacy of miltefosine and marbofloxacin alone or in combination with allopurinol against clinical strains of Leishmania infantum.
Journal: Parasitology research 20120601
Title: Effects of miltefosine treatment in fibroblast cell cultures and in mice experimentally infected with Neospora caninum tachyzoites.
Journal: Parasitology 20120601
Title: Leishmaniasis: current status of available drugs and new potential drug targets.
Journal: Asian Pacific journal of tropical medicine 20120601
Title: Leishmania donovani mitochondrial iron superoxide dismutase A is released into the cytosol during miltefosine induced programmed cell death.
Journal: Molecular and biochemical parasitology 20120501
Title: Leishmania strains causing self-healing cutaneous leishmaniasis have greater susceptibility towards oxidative stress.
Journal: Free radical research 20120501
Title: Miltefosine enhances phagocytosis but decreases nitric oxide production by peritoneal macrophages of C57BL/6 mice.
Journal: International immunopharmacology 20120501
Title: Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis.
Journal: PLoS neglected tropical diseases 20120501
Title: A poor-quality generic drug for the treatment of visceral leishmaniasis: a case report and appeal.
Journal: PLoS neglected tropical diseases 20120501
Title: Giardia lamblia: a new target for miltefosine.
Journal: International journal for parasitology 20120501
Title: [Exotic imported disease and scourge of the poor].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20120417
Title: Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania.
Journal: Journal of medicinal chemistry 20120412
Title: Efficacy of miltefosine treatment in Leishmania amazonensis-infected BALB/c mice.
Journal: International journal of antimicrobial agents 20120401
Title: Miltefosine and cutaneous leishmaniasis.
Journal: Current opinion in infectious diseases 20120401
Title: Miltefosine triggers a strong proinflammatory cytokine response during visceral leishmaniasis: role of TLR4 and TLR9.
Journal: International immunopharmacology 20120401
Title: Leishmania resistance to miltefosine associated with genetic marker.
Journal: Emerging infectious diseases 20120401
Title: Characterization and identification of suspected counterfeit miltefosine capsules.
Journal: The Analyst 20120307
Title: Leishmaniasis in the United States: treatment in 2012.
Journal: The American journal of tropical medicine and hygiene 20120301
Title: Noninferiority of miltefosine versus meglumine antimoniate for cutaneous leishmaniasis in children.
Journal: The Journal of infectious diseases 20120215
Title: Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers.
Journal: Bioorganic & medicinal chemistry 20120215
Title: Efficacy of miltefosine for topical treatment of Acanthamoeba keratitis in Syrian hamsters.
Journal: Parasitology research 20120201
Title: Treatment of Leishmania donovani-infected hamsters with miltefosine: analysis of cytokine mRNA expression by real-time PCR, lymphoproliferation, nitrite production and antibody responses.
Journal: The Journal of antimicrobial chemotherapy 20120201
Title: Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles.
Journal: European journal of medicinal chemistry 20120201
Title: Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing.
Journal: PLoS neglected tropical diseases 20120201
Title: Identification of phospholipid species affected by miltefosine action in Leishmania donovani cultures using LC-ELSD, LC-ESI/MS, and multivariate data analysis.
Journal: Analytical and bioanalytical chemistry 20120101
Title: Synthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation.
Journal: European journal of medicinal chemistry 20120101
Title: Molecular and functional characterization of the ceramide synthase from Trypanosoma cruzi.
Journal: Molecular and biochemical parasitology 20120101
Title: Cutaneous leishmaniasis acquired in Jura, France.
Journal: Emerging infectious diseases 20120101
Title: Successful treatment of imported mucosal Leishmania infantum leishmaniasis with miltefosine after severe hypokalemia under meglumine antimoniate treatment.
Journal: Journal of travel medicine 20120101
Title: Development of splenic marginal zone lymphoma in a HIV-negative patient with visceral leishmaniasis.
Journal: Acta haematologica 20120101
Title: Relapse of kala-azar after use of multiple drugs: a case report and brief review of literature.
Journal: Indian journal of medical microbiology 20120101
Title: Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment.
Journal: PloS one 20120101
Title: Efficacy of oral miltefosine in visceral leishmaniasis in rural West Bengal, India.
Journal: Indian journal of pharmacology 20120101
Title: Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents.
Journal: Bioorganic & medicinal chemistry 20111215
Title: Novel 3-nitro-1H-1,2,4-triazole-based aliphatic and aromatic amines as anti-chagasic agents.
Journal: Journal of medicinal chemistry 20111208
Title: Dynamics of parasite clearance in cutaneous leishmaniasis patients treated with miltefosine.
Journal: PLoS neglected tropical diseases 20111201
Title: Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review.
Journal: Tropical biomedicine 20111201
Title: Miltefosine effectively modulates the cytokine milieu in Indian post kala-azar dermal leishmaniasis.
Journal: The Journal of infectious diseases 20111101
Title: Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).
Journal: Bioorganic & medicinal chemistry letters 20111101
Title: Treatment of imported New World cutaneous leishmaniasis in Germany.
Journal: International journal of dermatology 20111101
Title: Antileishmanial activity of a formulation of 2-n-propylquinoline by oral route in mice model.
Journal: Parasite (Paris, France) 20111101
Title: A rare case of Visceral leishmaniasis with multiple relapse and multi-drug unresponsive: successfully treated with combination therapy.
Journal: International journal of clinical pharmacy 20111001
Title: Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Effect of Pam3Cys induced protection on the therapeutic efficacy of miltefosine against experimental visceral leishmaniasis.
Journal: Peptides 20111001
Title: Evaluation of miltefosine for the treatment of dogs naturally infected with L. infantum (=L. chagasi) in Brazil.
Journal: Veterinary parasitology 20110927
Title: Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum.
Journal: Journal of natural products 20110923
Title: Mucosal Leishmania infantum infection.
Journal: Parasitology research 20110901
Title: Miltefosine induces apoptosis-like cell death in yeast via Cox9p in cytochrome c oxidase.
Journal: Molecular pharmacology 20110901
Title: Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.
Journal: Cell death & disease 20110901
Title: Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.
Journal: PLoS neglected tropical diseases 20110901
Title: Miltefosine as an effective choice in the treatment of post-kala-azar dermal leishmaniasis.
Journal: The British journal of dermatology 20110801
Title: Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection.
Journal: American journal of respiratory and critical care medicine 20110801
Title: Selenocyanates and diselenides: a new class of potent antileishmanial agents.
Journal: European journal of medicinal chemistry 20110801
Title: Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv.
Journal: Acta tropica 20110801
Title: Phase IV trial of miltefosine in adults and children for treatment of visceral leishmaniasis (kala-azar) in Bangladesh.
Journal: The American journal of tropical medicine and hygiene 20110701
Title: Tender ulceronecrotic nodules in a patient with leukemia. Cutaneous acanthamebiasis.
Journal: Archives of dermatology 20110701
Title: Lipid-like sulfoxides and amine oxides as inhibitors of mast cell activation.
Journal: European journal of medicinal chemistry 20110601
Title: Weak cytotoxic activity of miltefosine against clinical isolates of Acanthamoeba spp.
Journal: The Journal of parasitology 20110601
Title: The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant Leishmania species of Brazil.
Journal: Memorias do Instituto Oswaldo Cruz 20110601
Title: Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes.
Journal: Memorias do Instituto Oswaldo Cruz 20110601
Title: Synthesis and evaluation of new furanyl and thiophenyl azoles as antileishmanial agents.
Journal: European journal of medicinal chemistry 20110501
Title: Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
Journal: Bioorganic & medicinal chemistry letters 20110501
Title: Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp.
Journal: Journal of natural products 20110425
Title: Cutaneous leishmaniasis after travel to Cyprus and successful treatment with miltefosine.
Journal: The American journal of tropical medicine and hygiene 20110405
Title: Antileishmanial efficacy of fluconazole and miltefosine in combination with an immunomodulator--picroliv.
Journal: Parasitology research 20110401
Title: Visceral leishmaniasis: elimination with existing interventions.
Journal: The Lancet. Infectious diseases 20110401
Title: In a trial of the use of miltefosine to treat HIV-related cryptosporidiosis in Zambian adults, extreme metabolic disturbances contribute to high mortality.
Journal: Annals of tropical medicine and parasitology 20110301
Title: Miltefosine-induced apoptotic cell death on Leishmania major and L. tropica strains.
Journal: The Korean journal of parasitology 20110301
Title: Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial.
Journal: Lancet (London, England) 20110205
Title: Combination therapy for visceral leishmaniasis.
Journal: Lancet (London, England) 20110205
Title: Randomized controlled clinical trial to access efficacy and safety of miltefosine in the treatment of cutaneous leishmaniasis Caused by Leishmania (Viannia) guyanensis in Manaus, Brazil.
Journal: The American journal of tropical medicine and hygiene 20110204
Title: Immunomodulatory effect of picroliv on the efficacy of paromomycin and miltefosine in combination in experimental visceral leishmaniasis.
Journal: Experimental parasitology 20110201
Title: Miltefosine, a promising novel agent for schistosomiasis mansoni.
Journal: International journal for parasitology 20110201
Title: Ambisome plus miltefosine for Indian patients with kala-azar.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20110201
Title: Pharmacovigilance methods in public health programmes: the example of miltefosine and visceral leishmaniasis.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20110201
Title: A species-specific approach to the use of non-antimony treatments for cutaneous leishmaniasis.
Journal: The American journal of tropical medicine and hygiene 20110105
Title: Monitoring of intracellular nitric oxide in leishmaniasis: its applicability in patients with visceral leishmaniasis.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20110101
Title: Exacerbation reaction (hypersensitivity) in post-kala-azar dermal leishmaniasis with miltefosine.
Journal: Indian journal of dermatology, venereology and leprology 20110101
Title: Bioactivity of miltefosine against aquatic stages of Schistosoma mansoni, Schistosoma haematobium and their snail hosts, supported by scanning electron microscopy.
Journal: Parasites & vectors 20110101
Title: Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial.
Journal: Trials 20110101
Title: Advances in the treatment of cutaneous leishmaniasis in the new world in the last ten years: a systematic literature review.
Journal: Anais brasileiros de dermatologia 20110101
Title: Antimonial resistance in Leishmania donovani is associated with increased in vivo parasite burden.
Journal: PloS one 20110101
Title: Miltefosine induces metacaspase and PARP genes expression in Leishmania infantum.
Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20110101
Title: Cutaneous leishmaniasis (Leishmania major infection) in Dutch troops deployed in northern Afghanistan: epidemiology, clinical aspects, and treatment.
Journal: The American journal of tropical medicine and hygiene 20101206
Title: Flow cytometric screening for anti-leishmanials in a human macrophage cell line.
Journal: Experimental parasitology 20101201
Title: Drug combinations for visceral leishmaniasis.
Journal: Current opinion in infectious diseases 20101201
Title: Miltefosine in the treatment of cutaneous leishmaniasis caused by Leishmania braziliensis in Brazil: a randomized and controlled trial.
Journal: PLoS neglected tropical diseases 20101201
Title: QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids.
Journal: European journal of medicinal chemistry 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: 2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.
Journal: Bioorganic & medicinal chemistry 20101101
Title: Design and synthesis of new adamantyl-substituted antileishmanial ether phospholipids.
Journal: Bioorganic & medicinal chemistry letters 20100915
Title: Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis.
Journal: Allergy 20100901
Title: Synthesis and preliminary bioactivity assays of 3,4-dichloro-5-(omega-hydroxyalkylamino)-2(5H)-furanones.
Journal: European journal of medicinal chemistry 20100901
Title: Cost-effectiveness analysis of combination therapies for visceral leishmaniasis in the Indian subcontinent.
Journal: PLoS neglected tropical diseases 20100901
Title: Treatment of visceral leishmaniasis in 2010: direction from Bihar State, India.
Journal: Future microbiology 20100901
Title: Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium.
Journal: Journal of natural products 20100827
Title: Efficacy of miltefosine for the treatment of American cutaneous leishmaniasis.
Journal: The American journal of tropical medicine and hygiene 20100805
Title: Synthesis and antileishmanial activity of piperoyl-amino acid conjugates.
Journal: European journal of medicinal chemistry 20100801
Title: Current diagnosis and treatment of visceral leishmaniasis.
Journal: Expert review of anti-infective therapy 20100801
Title: Visceral leishmaniasis in children: a review.
Journal: Minerva pediatrica 20100801
Title: Surface-active properties of nitrogen heterocyclic and dialkylamino derivates of hexadecylphosphocholine and cetyltrimethylammonium bromide.
Journal: Journal of colloid and interface science 20100715
Title: Successful treatment of Balamuthia mandrillaris amoebic infection with extensive neurological and cutaneous involvement.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100715
Title: Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites.
Journal: International journal of antimicrobial agents 20100701
Title: CpG oligodeoxynucleotide augments the antileishmanial activity of miltefosine against experimental visceral leishmaniasis.
Journal: The Journal of antimicrobial chemotherapy 20100701
Title: Visceral Leishmaniasis treated with antimonials/paromomycin followed by itraconazole/miltefosine after standard therapy failures in a human immunodeficiency virus-infected patient.
Journal: The American journal of tropical medicine and hygiene 20100701
Title: Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas.
Journal: Blood 20100603
Title: Computational screening for membrane-directed inhibitors of mast cell activation.
Journal: European journal of medicinal chemistry 20100601
Title: Synthesis and molecular docking studies of 1-phenyl-4-glycosyl-dihydropyridines as potent antileishmanial agents.
Journal: European journal of medicinal chemistry 20100601
Title: Selection and phenotype characterization of potassium antimony tartrate-resistant populations of four New World Leishmania species.
Journal: Parasitology research 20100601
Title: Use of miltefosine in the treatment of visceral leishmaniasis in children at a tertiary care hospital of Karachi.
Journal: JPMA. The Journal of the Pakistan Medical Association 20100601
Title: Oral miltefosine in post-kala-azar dermal leishmaniasis--experience in three cases.
Journal: International journal of dermatology 20100501
Title: Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi.
Journal: Bioorganic & medicinal chemistry letters 20100315
Title: Combination therapy for visceral leishmaniasis.
Journal: The Lancet. Infectious diseases 20100301
Title: The putative lipid raft modulator miltefosine displays immunomodulatory action in T-cell dependent dermal inflammation models.
Journal: European journal of pharmacology 20100225
Title: New benzophenone-derived bisphosphonium salts as leishmanicidal leads targeting mitochondria through inhibition of respiratory complex II.
Journal: Journal of medicinal chemistry 20100225
Title: Fluorinated rhodacyanine (SJL-01) possessing high efficacy for visceral leishmaniasis (VL).
Journal: Journal of medicinal chemistry 20100114
Title: Effects of topical treatment with the raft modulator miltefosine and clobetasol in cutaneous mastocytosis: a randomized, double-blind, placebo-controlled trial.
Journal: The British journal of dermatology 20100101
Title: Synthesis and biological evaluation of trifluralin analogues as antileishmanial agents.
Journal: Bioorganic & medicinal chemistry 20100101
Title: Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines.
Journal: Bioorganic & medicinal chemistry 20100101
Title: Miltefosine treatment of Leishmania major infection: an observational study involving Dutch military personnel returning from northern Afghanistan.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100101
Title: Resolution of cutaneous old world and new world leishmaniasis after oral miltefosine treatment.
Journal: The American journal of tropical medicine and hygiene 20100101
Title: Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids.
Journal: Lipids in health and disease 20100101
Title: Study of efficacy of miltefosine and allopurinol in dogs with leishmaniosis.
Journal: Veterinary journal (London, England : 1997) 20091201
Title: Dialkylamino and nitrogen heterocyclic analogues of hexadecylphosphocholine and cetyltrimetylammonium bromide: effect of phosphate group and environment of the ammonium cation on their biological activity.
Journal: European journal of medicinal chemistry 20091201
Title: Combined topical paromomycin and oral miltefosine treatment of mice experimentally infected with Leishmania (Leishmania) major leads to reduction in both lesion size and systemic parasite burdens.
Journal: The Journal of antimicrobial chemotherapy 20091201
Title: Anti-trypanosomatid benzofuroxans and deoxygenated analogues: synthesis using polymer-supported triphenylphosphine, biological evaluation and mechanism of action studies.
Journal: European journal of medicinal chemistry 20091201
Title: Post-kala-azar dermal leishmaniasis (PKDL) developing after treatment of visceral leishmaniasis with amphotericin B and miltefosine.
Journal: Annals of tropical medicine and parasitology 20091201
Title: Synthesis and biological activity of dialkylphosphocholines.
Journal: Bioorganic & medicinal chemistry letters 20091115
Title: Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles.
Journal: Journal of medicinal chemistry 20091112
Title: Second generation of 2H-benzimidazole 1,3-dioxide derivatives as anti-trypanosomatid agents: synthesis, biological evaluation, and mode of action studies.
Journal: European journal of medicinal chemistry 20091101
Title: Membrane sterol depletion impairs miltefosine action in wild-type and miltefosine-resistant Leishmania donovani promastigotes.
Journal: The Journal of antimicrobial chemotherapy 20091101
Title: Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.
Journal: Bioorganic & medicinal chemistry 20091015
Title: Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine-aplysinopsin hybrid molecule.
Journal: Journal of medicinal chemistry 20091008
Title: Administration of miltefosine and meglumine antimoniate in healthy dogs: clinicopathological evaluation of the impact on the kidneys.
Journal: Toxicologic pathology 20091001
Title: Multicentric, controlled clinical study to evaluate effectiveness and safety of miltefosine and allopurinol for canine leishmaniosis.
Journal: Veterinary dermatology 20091001
Title: Anti-acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent.
Journal: The Journal of antimicrobial chemotherapy 20090901
Title: Efficacy of extended (six weeks) treatment with miltefosine for mucosal leishmaniasis in Bolivia.
Journal: The American journal of tropical medicine and hygiene 20090901
Title: In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole.
Journal: Biomedica : revista del Instituto Nacional de Salud 20090901
Title: Clinical efficacy and tolerance of miltefosine in the treatment of canine leishmaniosis.
Journal: Parasitology research 20090801
Title: Flow cytometric determination of intracellular non-protein thiols in Leishmania promastigotes using 5-chloromethyl fluorescein diacetate.
Journal: Experimental parasitology 20090801
Title: Highly effective oral amphotericin B formulation against murine visceral leishmaniasis.
Journal: The Journal of infectious diseases 20090801
Title: Cost-effectiveness projections of single and combination therapies for visceral leishmaniasis in Bihar, India.
Journal: Tropical medicine & international health : TM & IH 20090801
Title: Cutaneous leishmaniasis with lymphadenopathy due to Leishmania donovani.
Journal: Clinical and experimental dermatology 20090701
Title: Comparative study on the short term efficacy and adverse effects of miltefosine and meglumine antimoniate in dogs with natural leishmaniosis.
Journal: Parasitology research 20090701
Title: Successful use of miltefosine and sodium stibogluconate, in combination, for the treatment of an HIV-positive patient with visceral leishmaniasis: a case report and brief review of the literature.
Journal: Annals of tropical medicine and parasitology 20090701
Title: Hexadecylphosphocholine alters nonvesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells.
Journal: The international journal of biochemistry & cell biology 20090601
Title: Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase.
Journal: Bioorganic & medicinal chemistry letters 20090601
Title: Miltefosine promotes IFN-gamma-dominated anti-leishmanial immune response.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20090601
Title: Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090501
Title: Autotaxin structure-activity relationships revealed through lysophosphatidylcholine analogs.
Journal: Bioorganic & medicinal chemistry 20090501
Title: Relapse of visceral leishmaniasis after miltefosine treatment in a Nepalese patient.
Journal: The American journal of tropical medicine and hygiene 20090401
Title: Neurotoxicity of inverted-cone shaped lipids.
Journal: Neurotoxicology 20090301
Title: Miltefosine to treat cutaneous leishmaniasis caused by Leishmania tropica.
Journal: Annals of tropical medicine and parasitology 20090301
Title: Short report: Development of post-kala-azar dermal leishmaniasis (PKDL) in miltefosine-treated visceral leishmaniasis.
Journal: The American journal of tropical medicine and hygiene 20090301
Title: Cellular transport and lipid interactions of miltefosine.
Journal: Current drug metabolism 20090301
Title: [Mucosal complication of cutaneous leishmaniasis].
Journal: Biomedica : revista del Instituto Nacional de Salud 20090301
Title: Miltefosine inhibits human mast cell activation and mediator release both in vitro and in vivo.
Journal: The Journal of investigative dermatology 20090201
Title: Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies.
Journal: Bioorganic & medicinal chemistry 20090115
Title: Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity.
Journal: Bioorganic & medicinal chemistry letters 20090115
Title: Na(+)-ATPase and protein kinase C are targets to 1-O-hexadecylphosphocoline (miltefosine) in Trypanosoma cruzi.
Journal: Archives of biochemistry and biophysics 20090101
Title: Anthropometrically derived dosing and drug costing calculations for treating visceral leishmaniasis in Bihar, India.
Journal: Tropical medicine & international health : TM & IH 20090101
Title: Cutaneous leishmaniasis with boggy induration and simultaneous mucosal disease.
Journal: The American journal of tropical medicine and hygiene 20090101
Title: Visceral leishmaniasis simulating chronic liver disease: successful treatment with miltefosine.
Journal: Indian journal of medical microbiology 20090101
Title: Newer strategies for the kala-azar elimination programme in India.
Journal: The Indian journal of medical research 20090101
Title: Distinctive molecular signaling in triple-negative breast cancer cell death triggered by hexadecylphosphocholine (miltefosine).
Journal: FEBS letters 20081224
Title: Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine.
Journal: Bioorganic & medicinal chemistry letters 20081215
Title: In pursuit of natural product leads: synthesis and biological evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4-carboxylic acid (A-33853) and its analogues: discovery of N-(2-benzoxazol-2-ylphenyl)benzamides as novel antileishmanial chemotypes.
Journal: Journal of medicinal chemistry 20081211
Title: Cutaneous infection with Leishmania infantum in an infant treated successfully with miltefosine.
Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20081201
Title: Efficacy of pentavalent antimony, amphotericin B, and miltefosine in Leishmania amazonensis-infected macrophages under normoxic and hypoxic conditions.
Journal: The Journal of parasitology 20081201
Title: Acanthamoeba infection in a patient with chronic graft-versus-host disease occurring during treatment with voriconazole.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20081201
Title: Leishmania DNA quantification by real-time PCR in naturally infected dogs treated with miltefosine.
Journal: Annals of the New York Academy of Sciences 20081201
Title: Immune response following miltefosine therapy in a patient with post-kala-azar dermal leishmaniasis.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101
Title: Involvement of miltefosine-mediated ERK activation in glioma cell apoptosis through Fas regulation.
Journal: Journal of neurochemistry 20081101
Title: Interferon-gamma (INF-gamma), IL4 expression levels and Leishmania DNA load as prognostic markers for monitoring response to treatment of leishmaniotic dogs with miltefosine and allopurinol.
Journal: Cytokine 20081101
Title: Successful treatment of disseminated Acanthamoeba sp. infection with miltefosine.
Journal: Emerging infectious diseases 20081101
Title: Post-Kala-Azar dermal leishmaniasis in an HIV-1-infected woman: recovery after amphotericin B following failure of oral miltefosine.
Journal: The American journal of tropical medicine and hygiene 20081101
Title: New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081015
Title: Identification of a Leishmania infantum gene mediating resistance to miltefosine and SbIII.
Journal: International journal for parasitology 20081001
Title: Development of new antileishmanial drugs--current knowledge and future prospects.
Journal: Journal of enzyme inhibition and medicinal chemistry 20081001
Title: In vivo activity of perifosine against Leishmania amazonensis.
Journal: Acta tropica 20081001
Title: In vitro antileishmanial activity of fluoro-artemisinin derivatives against Leishmania donovani.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080901
Title: Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp.
Journal: Journal of natural products 20080901
Title: Furoxan-, alkylnitrate-derivatives and related compounds as anti-trypanosomatid agents: mechanism of action studies.
Journal: Bioorganic & medicinal chemistry 20080901
Title: Treatment of leishmaniasis with miltefosine: 2008 status.
Journal: Expert opinion on drug metabolism & toxicology 20080901
Title: Isolation of Leishmania tropica from a patient with visceral leishmaniasis and disseminated cutaneous leishmaniasis, southern Iran.
Journal: The American journal of tropical medicine and hygiene 20080901
Title: Parallel synthesis and antileishmanial activity of ether-linked phospholipids.
Journal: Bioorganic & medicinal chemistry letters 20080815
Title: Pharmacokinetics of miltefosine in Old World cutaneous leishmaniasis patients.
Journal: Antimicrobial agents and chemotherapy 20080801
Title: In vitro and in vivo activity of miltefosine against penicillin-sensitive and -resistant Streptococcus pneumoniae strains.
Journal: Journal of chemotherapy (Florence, Italy) 20080801
Title: Leishmania infection can hamper immune recovery in virologically suppressed HIV-infected patients.
Journal: The new microbiologica 20080701
Title: Proteomic analysis of miltefosine-resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A (eIF4A).
Journal: International journal of antimicrobial agents 20080601
Title: [New antiparasitic drugs].
Journal: La Revue de medecine interne 20080601
Title: Biorelevant refinement of the Caco-2 cell culture model to assess efficacy of paracellular permeability enhancers.
Journal: Journal of pharmaceutical sciences 20080501
Title: Hexadecylphosphocholine interferes with the intracellular transport of cholesterol in HepG2 cells.
Journal: The FEBS journal 20080401
Title: Development and validation of a quantitative assay for the measurement of miltefosine in human plasma by liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080401
Title: Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity.
Journal: Bioorganic & medicinal chemistry letters 20080401
Title: HIV infection, visceral leishmaniasis and Guillain-Barré syndrome in the same patient: a case report.
Journal: Annals of tropical medicine and parasitology 20080301
Title: Design and synthesis of potent antileishmanial cycloalkylidene-substituted ether phospholipid derivatives.
Journal: Journal of medicinal chemistry 20080227
Title: Successful treatment of a married couple for American leishmaniasis with miltefosine.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080201
Title: Efficacy of miltefosine for Bolivian cutaneous leishmaniasis.
Journal: The American journal of tropical medicine and hygiene 20080201
Title: Oral miltefosine treatment in children with visceral leishmaniasis: a brief review.
Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20080201
Title: Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: active ingredient and mediator of drug release.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20080122
Title: Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids.
Journal: European journal of medicinal chemistry 20080101
Title: Long term failure of miltefosine in the treatment of refractory visceral leishmaniasis in AIDS patients.
Journal: Scandinavian journal of infectious diseases 20080101
Title: Oral miltefosine in the treatment of post-kala-azar dermal leishmaniasis.
Journal: Clinical and experimental dermatology 20080101
Title: Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy.
Journal: Retrovirology 20080101
Title: Miltefosine for visceral leishmaniasis relapse treatment and secondary prophylaxis in HIV-infected patients.
Journal: Scandinavian journal of infectious diseases 20080101
Title: [Comparative study between oral miltefosine and parenteral N-metil glucamine antimoniate for the treatment of experimental leishmaniasis caused Leishmania (Leishmania) amazonensis].
Journal: Revista da Sociedade Brasileira de Medicina Tropical 20080101
Title: Synthesis and biological evaluation of fluorescent leishmanicidal analogues of hexadecylphosphocholine (miltefosine) as probes of antiparasite mechanisms.
Journal: Journal of medicinal chemistry 20071129
Title: Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives.
Journal: Journal of medicinal chemistry 20071115
Title: Quinuclidine derivatives as potential antiparasitics.
Journal: Antimicrobial agents and chemotherapy 20071101
Title: Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli.
Journal: Bioorganic & medicinal chemistry 20071101
Title: Post-kala-azar dermal leishmaniasis as an immune reconstitution inflammatory syndrome in a patient with acquired immune deficiency syndrome.
Journal: The British journal of dermatology 20071101
Title: Glucantime-resistant Leishmania tropica isolated from Iranian patients with cutaneous leishmaniasis are sensitive to alternative antileishmania drugs.
Journal: Parasitology research 20071001
Title: Miltefosine in the treatment of a case of visceral leishmaniasis with renal dysfunction.
Journal: Annals of tropical medicine and parasitology 20071001
Title: Effect of alkyl-lysophospholipids on some aspects of the metabolism of Leishmania donovani.
Journal: The Journal of parasitology 20071001
Title: Miltefosine in the treatment of leishmaniasis: Clinical evidence for informed clinical risk management.
Journal: Therapeutics and clinical risk management 20071001
Title: Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo.
Journal: International journal of antimicrobial agents 20070901
Title: Wilson disease with visceral leishmaniasis: an extremely uncommon presentation.
Journal: The American journal of tropical medicine and hygiene 20070901
Title: Phase 4 trial of miltefosine for the treatment of Indian visceral leishmaniasis.
Journal: The Journal of infectious diseases 20070815
Title: Synthesis, antifungal and antimicrobial activity of alkylphospholipids.
Journal: Bioorganic & medicinal chemistry 20070801
Title: [The leishmaniasis - a parasitel infection as differential diagnosis of malignant tumours of oral mucosa. A case report and review of literature].
Journal: Mund-, Kiefer- und Gesichtschirurgie : MKG 20070801
Title: Lysosomal and mitochondrial pathways in miltefosine-induced apoptosis in U937 cells.
Journal: Apoptosis : an international journal on programmed cell death 20070701
Title: Comparison of miltefosine and meglumine antimoniate for the treatment of zoonotic cutaneous leishmaniasis (ZCL) by a randomized clinical trial in Iran.
Journal: Acta tropica 20070701
Title: Pharmacovigilance in kala-azar patients with severe thrombocytopenia caused by sodium antimony gluconate & miltefosine.
Journal: The Indian journal of medical research 20070701
Title: Diffuse cutaneous leishmaniasis responds to miltefosine but then relapses.
Journal: The British journal of dermatology 20070601
Title: Mucosal leishmaniasis and miltefosine.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070601
Title: A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids.
Journal: Molecular microbiology 20070601
Title: Miltefosine induces apoptosis in arsenite-resistant Leishmania donovani promastigotes through mitochondrial dysfunction.
Journal: Experimental parasitology 20070501
Title: Chemotherapy of leishmaniasis. Part V: Synthesis and in vitro bioevaluation of novel pyridinone derivatives.
Journal: European journal of medicinal chemistry 20070501
Title: [Cutaneous leishmaniasis].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20070501
Title: Chronic cutaneous leishmaniasis in an immunocompetent patient: response to miltefosine.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20070501
Title: Cutaneous leishmaniasis treatment.
Journal: Travel medicine and infectious disease 20070501
Title: Topical agents and dressings for fungating wounds.
Journal: The Cochrane database of systematic reviews 20070418
Title: Chemotherapy of leishmaniasis Part VI: synthesis and bioevaluation of some novel terpenyl S,N- and N,N-acetals.
Journal: European journal of medicinal chemistry 20070401
Title: Inward translocation of the phospholipid analogue miltefosine across Caco-2 cell membranes exhibits characteristics of a carrier-mediated process.
Journal: Lipids 20070401
Title: First case of typical Old World cutaneous leishmaniasis treated with miltefosine.
Journal: International journal of dermatology 20070401
Title: Intestinal absorption of miltefosine: contribution of passive paracellular transport.
Journal: Pharmaceutical research 20070301
Title: Miltefosine in cutaneous leishmaniasis.
Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20070301
Title: Treatment of Bolivian mucosal leishmaniasis with miltefosine.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070201
Title: Drug policy for visceral leishmaniasis: a cost-effectiveness analysis.
Journal: Tropical medicine & international health : TM & IH 20070201
Title: [Treatment of visceral leishmaniasis in children].
Journal: Medecine tropicale : revue du Corps de sante colonial 20070201
Title: Oral miltefosine to treat new world cutaneous leishmaniasis.
Journal: The Lancet. Infectious diseases 20070101
Title: In vitro and in vivo antileishmanial efficacy of a new nitrilquinoline against Leishmania donovani.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070101
Title: Physicochemical characterization of molecular assemblies of miltefosine and amphotericin B.
Journal: Molecular pharmaceutics 20070101
Title: Chemotherapy of leishmaniasis: past, present and future.
Journal: Current medicinal chemistry 20070101
Title: [Miltefosine: a new remedy for leishmaniasis].
Journal: Nederlands tijdschrift voor geneeskunde 20061209
Title: Quantification of the response to miltefosine treatment for visceral leishmaniasis by QT-NASBA.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: Oral miltefosine for the treatment of Indian visceral leishmaniasis.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: TDR collaboration with the pharmaceutical industry.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: Development of miltefosine as an oral treatment for leishmaniasis.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: Miltefosine: issues to be addressed in the future.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: Miltefosine--discovery of the antileishmanial activity of phospholipid derivatives.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: Treatment of New World cutaneous leishmaniasis with miltefosine.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201
Title: Relapse of new world diffuse cutaneous leishmaniasis caused by Leishmania (Leishmania) mexicana after miltefosine treatment.
Journal: The American journal of tropical medicine and hygiene 20061201
Title: Miltefosine in children with visceral leishmaniasis.
Journal: Indian pediatrics 20061201
Title: Miltefosine in children with visceral leishmaniasis: a prospective, multicentric, cross-sectional study.
Journal: Indian journal of pediatrics 20061201
Title: A phase II trial of miltefosine in patients with cutaneous T-cell lymphoma.
Journal: Bulletin du cancer 20061101
Title: Synthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity.
Journal: Bioorganic & medicinal chemistry letters 20061001
Title: Aspects of the cytological activity of edelfosine, miltefosine, and ilmofosine in Leishmania donovani.
Journal: The Journal of parasitology 20061001
Title: [Miltefosine for disseminated cutaneous leishmaniasis].
Journal: Biomedica : revista del Instituto Nacional de Salud 20061001
Title: [Oral miltefosine to treat leishmaniasis].
Journal: Biomedica : revista del Instituto Nacional de Salud 20061001
Title: The influence of subphase temperature on miltefosine-cholesterol mixed monolayers.
Journal: Journal of colloid and interface science 20060901
Title: Hexadecyl-phosphorylcholine ointment for treatment of cutaneous leishmaniasis: an animal trial.
Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20060901
Title: Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites.
Journal: The Journal of biological chemistry 20060818
Title: A comparison of miltefosine and sodium stibogluconate for treatment of visceral leishmaniasis in an Ethiopian population with high prevalence of HIV infection.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060801
Title: Visceral leishmaniasis (kala-azar)--the Bihar (India) perspective.
Journal: The Journal of infection 20060701
Title: Successful treatment of post-kala-azar dermal leishmaniasis (PKDL) in a HIV infected patient with multiple relapsing leishmaniasis from Western Europe.
Journal: The Journal of infection 20060701
Title: Development of a semi-automated colorimetric assay for screening anti-leishmanial agents.
Journal: Journal of microbiological methods 20060701
Title: Cure of antimony-unresponsive Indian post-kala-azar dermal leishmaniasis with oral miltefosine.
Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20060701
Title: The anti-leishmanial drug miltefosine causes insulin resistance in skeletal muscle cells in vitro.
Journal: Diabetologia 20060701
Title: A keratitis rat model for evaluation of anti-Acanthamoeba polyphaga agents.
Journal: Cornea 20060601
Title: Treatment of diffuse cutaneous leishmaniasis with miltefosine: a case report.
Journal: International journal of dermatology 20060601
Title: HPLC detection of miltefosine using an evaporative light scattering detector.
Journal: Die Pharmazie 20060501
Title: Hexadecylphosphocholine disrupts cholesterol homeostasis and induces the accumulation of free cholesterol in HepG2 tumour cells.
Journal: Biochemical pharmacology 20060414
Title: Miltefosine: oral treatment of leishmaniasis.
Journal: Expert review of anti-infective therapy 20060401
Title: Successful miltefosine treatment of post-kala-azar dermal leishmaniasis occurring during antiretroviral therapy.
Journal: Annals of tropical medicine and parasitology 20060401
Title: Childhood visceral leishmaniasis.
Journal: The Indian journal of medical research 20060301
Title: Drug unresponsiveness & combination therapy for kala-azar.
Journal: The Indian journal of medical research 20060301
Title: Current scenario of drug development for leishmaniasis.
Journal: The Indian journal of medical research 20060301
Title: Synthesis and antiprotozoal activity of some new synthetic substituted quinoxalines.
Journal: Bioorganic & medicinal chemistry letters 20060215
Title: Modulation of intestinal barrier properties by miltefosine.
Journal: Biochemical pharmacology 20060214
Title: In vitro activity of hexadecylphosphocholine (miltefosine) against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis.
Journal: The Journal of antimicrobial chemotherapy 20060201
Title: Hexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis.
Journal: Antimicrobial agents and chemotherapy 20060201
Title: Development of miltefosine for the leishmaniases.
Journal: Mini reviews in medicinal chemistry 20060201
Title: Miltefosine decreases the cytotoxic effect of epirubicine and cyclophosphamide on mouse spermatogenic, thymic and bone marrow cells.
Journal: Archives of toxicology 20060101
Title: A liposomal formulation of doxorubicin, composed of hexadecylphosphocholine (HePC): physicochemical characterization and cytotoxic activity against human cancer cell lines.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20060101
Title: Antitumor activity of doxorubicin encapsulated in hexadecylphosphocholine (HePC) liposomes against human xenografts on Scid mice.
Journal: In vivo (Athens, Greece) 20060101
Title: In-vitro activity of miltefosine and voriconazole on clinical isolates of free-living amebas: Balamuthia mandrillaris, Acanthamoeba spp., and Naegleria fowleri.
Journal: The Journal of eukaryotic microbiology 20060101
Title: Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use.
Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20060101
Title: Bite the hand that sprays you.
Journal: Skinmed 20060101
Title: Antileishmanial and trypanocidal activities of new miltefosine liposomal formulations.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051201
Title: Clinical status of agents being developed for leishmaniasis.
Journal: Expert opinion on investigational drugs 20051101
Title: Glucosamine-glycerophospholipids that activate cell-matrix adhesion and migration.
Journal: Journal of medicinal chemistry 20051020
Title: Synthesis and biological evaluation of spin-labeled alkylphospholipid analogs.
Journal: Journal of medicinal chemistry 20051006
Title: Use of Leishmania donovani field isolates expressing the luciferase reporter gene in in vitro drug screening.
Journal: Antimicrobial agents and chemotherapy 20050901
Title: The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine.
Journal: The American journal of tropical medicine and hygiene 20050801
Title: Miltefosine to treat leishmaniasis.
Journal: Expert opinion on pharmacotherapy 20050701
Title: Successful treatment with miltefosine of disseminated cutaneous leishmaniasis in a severely immunocompromised patient infected with HIV-1.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050615
Title: Development of a modified MTT assay for screening antimonial resistant field isolates of Indian visceral leishmaniasis.
Journal: Parasitology international 20050601
Title: Refractoriness to the treatment of sodium stibogluconate in Indian kala-azar field isolates persist in in vitro and in vivo experimental models.
Journal: Parasitology research 20050601
Title: Challenges in the management of visceral leishmaniasis.
Journal: Indian pediatrics 20050601
Title: Anti-proliferative synergy of lysophospholipid analogues and ketoconazole against Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae): cellular and ultrastructural analysis.
Journal: The Journal of antimicrobial chemotherapy 20050501
Title: Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound.
Journal: Journal of natural products 20050501
Title: Availability of miltefosine for the treatment of kala-azar in India.
Journal: Bulletin of the World Health Organization 20050501
Title: Efficacy of Desmodium gangeticum extract and its fractions against experimental visceral leishmaniasis.
Journal: Journal of ethnopharmacology 20050408
Title: Effects of miltefosine on membrane permeability and accumulation of [99mTc]-hexakis-2-methoxyisobutyl isonitrile, 2-[18F]fluoro-2-deoxy-D-glucose, daunorubucin and rhodamine123 in multidrug-resistant and sensitive cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050401
Title: [Treatment of cutaneous metastases of a squamous cell carcinoma of the leg with topical miltefosine].
Journal: Annales de dermatologie et de venereologie 20050401
Title: Efficacy of picroliv in combination with miltefosine, an orally effective antileishmanial drug against experimental visceral leishmaniasis.
Journal: Acta tropica 20050401
Title: Interactions between the ganglioside GM1 and hexadecylphosphocholine (miltefosine) in monolayers at the air/water interface.
Journal: Colloids and surfaces. B, Biointerfaces 20050310
Title: Recent Developments in Leishmaniasis: Epidemiology, Diagnosis, and Treatment.
Journal: Current infectious disease reports 20050101
Title: Leishmanicidal activity of edelfosine, miltefosine and ilmofosine.
Journal: Basic & clinical pharmacology & toxicology 20050101
Title: Magnitude of unresponsiveness to sodium stibogluconate in the treatment of visceral leishmaniasis in Bihar.
Journal: The National medical journal of India 20050101
Title: Loco-regional control of cutaneous metastases of malignant melanoma by treatment with miltefosine (Miltex).
Journal: Acta oncologica (Stockholm, Sweden) 20050101
Title: [Visceral leishmaniases].
Journal: La Revue du praticien 20041231
Title: Surface behavior of oleoyl palmitoyl phosphatidyl ethanolamine (OPPE) and the characteristics of mixed OPPE-miltefosine monolayers.
Journal: Langmuir : the ACS journal of surfaces and colloids 20041221
Title: Challenges and new discoveries in the treatment of leishmaniasis.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20041201
Title: Ancistrobenomine a, the first naphthylisoquinoline oxygenated at Me-3, and related 5,1'-coupled alkaloids, from the 'new' plant species ancistrocladusbenomensis.
Journal: Journal of natural products 20041201
Title: Oral miltefosine for leishmaniasis in immunocompromised patients: compassionate use in 39 patients with HIV infection.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041115
Title: Miltefosine (Impavido): the first oral treatment against leishmaniasis.
Journal: Medical microbiology and immunology 20041101
Title: Hexadecylphosphocholine causes rapid cell death in canine mammary tumour cells.
Journal: European journal of pharmacology 20041019
Title: Effect of the lysophospholipid analogues edelfosine, ilmofosine and miltefosine against Leishmania amazonensis.
Journal: The Journal of antimicrobial chemotherapy 20041001
Title: Short report: fluorescent Leishmania: application to anti-leishmanial drug testing.
Journal: The American journal of tropical medicine and hygiene 20041001
Title: Leishmaniasis.
Journal: Nature reviews. Microbiology 20040901
Title: Miltefosine for new world cutaneous leishmaniasis.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040501
Title: Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.
Journal: Journal of natural products 20040501
Title: Progress in the treatment of a neglected infectious disease: visceral leishmaniasis.
Journal: Expert review of anti-infective therapy 20040401
Title: Inhibition of phosphatidylcholine synthesis is not the primary pathway in hexadecylphosphocholine-induced apoptosis.
Journal: Biochimica et biophysica acta 20040322
Title: Hexadecylphosphocholine interaction with lipid monolayers.
Journal: Biochimica et biophysica acta 20040309
Title: Miltefosine-cholesterol interactions: a monolayer study.
Journal: Langmuir : the ACS journal of surfaces and colloids 20040203
Title: [Multiple cutaneous plasmocytoma treated with topical applications of miltefosine].
Journal: Annales de dermatologie et de venereologie 20040201
Title: Miltefosine: an oral drug for visceral leishmaniasis.
Journal: Indian journal of pediatrics 20040201
Title: Efficacy and tolerability of miltefosine for childhood visceral leishmaniasis in India.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040115
Title: Controlled plasmid gene transfer to murine renal carcinoma by hexadecylphosphocholine.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20040108
Title: Hexadecylphosphocholine inhibits phosphatidylcholine synthesis via both the methylation of phosphatidylethanolamine and CDP-choline pathways in HepG2 cells.
Journal: The international journal of biochemistry & cell biology 20040101
Title: [Leishmaniasis--oral treatment with hexadecylphosphocholine].
Journal: Wiener klinische Wochenschrift 20040101
Title: Functional cloning of the miltefosine transporter. A novel P-type phospholipid translocase from Leishmania involved in drug resistance.
Journal: The Journal of biological chemistry 20031212
Title: Synthesis and antiproliferative activity of alkylphosphocholines.
Journal: Chemistry and physics of lipids 20031201
Title: [Visceral leishmaniasis: new drugs].
Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20031201
Title: Cutaneous leishmaniasis: current and future management.
Journal: Expert review of anti-infective therapy 20031201
Title: Current treatment approaches to leishmaniasis.
Journal: Current opinion in infectious diseases 20031001
Title: Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine).
Journal: International journal of antimicrobial agents 20031001
Title: Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine.
Journal: The Journal of biological chemistry 20030919
Title: Single-dose liposomal amphotericin B in the treatment of visceral leishmaniasis in India: a multicenter study.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030915
Title: Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis.
Journal: Journal of natural products 20030901
Title: Treatment of Acanthamoeba keratitis.
Journal: Expert review of anti-infective therapy 20030801
Title: Breakthrough in the management of visceral leishmaniasis.
Journal: The Journal of the Association of Physicians of India 20030701
Title: Orally effective drugs for kala-azar (visceral leishmaniasis): focus on miltefosine and sitamaquine.
Journal: The Journal of the Association of Physicians of India 20030701
Title: The activity of diguanidino and 'reversed' diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani.
Journal: Bioorganic & medicinal chemistry letters 20030616
Title: Oral miltefosine treatment in children with mild to moderate Indian visceral leishmaniasis.
Journal: The Pediatric infectious disease journal 20030501
Title: [New drugs for treatment of parasitic infections].
Journal: Casopis lekaru ceskych 20030301
Title: Antileishmanial ring-substituted ether phospholipids.
Journal: Journal of medicinal chemistry 20030227
Title: Miltefosine for Indian visceral leishmaniasis.
Journal: The New England journal of medicine 20030227
Title: Miltefosine for Indian visceral leishmaniasis.
Journal: The New England journal of medicine 20030227
Title: Role of phospholipase C-beta in the modulation of epithelial tight junction permeability.
Journal: The Journal of pharmacology and experimental therapeutics 20030201
Title: Miltefosine in visceral leishmaniasis.
Journal: The Lancet. Infectious diseases 20030201
Title: Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway.
Journal: Anti-cancer drugs 20030201
Title: Antiprotozoal activities of phospholipid analogues.
Journal: Molecular and biochemical parasitology 20030201
Title: Alkylphospholipids reversibly open epithelial tight junctions.
Journal: Anticancer research 20030101
Title: Miltefosine: great expectations against visceral leishmaniasis.
Journal: Journal of postgraduate medicine 20030101
Title: An oral drug for leishmaniasis.
Journal: The New England journal of medicine 20021128
Title: Oral miltefosine for Indian visceral leishmaniasis.
Journal: The New England journal of medicine 20021128
Title: Kala-azar--progress against a neglected disease.
Journal: The New England journal of medicine 20021128
Title: Proinflammatory and cytotoxic effects of hexadecylphosphocholine (miltefosine) against drug-resistant strains of Trypanosoma cruzi.
Journal: Antimicrobial agents and chemotherapy 20021101
Title: Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins.
Journal: The Journal of biological chemistry 20020920
Title: Immunoblot analysis of the humoral immune response to Leishmania donovani polypeptides in cases of human visceral leishmaniasis: its usefulness in prognosis.
Journal: Clinical and diagnostic laboratory immunology 20020901
Title: Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells.
Journal: European journal of biochemistry 20020901
Title: New therapy for 'black fever' is 95% effective: India licenses the first oral drug for visceral leishmaniasis, a lethal disease of poverty.
Journal: Indian journal of medical sciences 20020901
Title: Treatment of visceral leishmaniasis: a review of current treatment practices.
Journal: Expert opinion on pharmacotherapy 20020801
Title: Miltefosine presents new hope for leishmaniasis patients.
Journal: The Lancet. Infectious diseases 20020801
Title: Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda.
Journal: The Lancet. Infectious diseases 20020801
Title: New therapy for visceral leishmaniasis.
Journal: Releve epidemiologique hebdomadaire 20020621
Title: Determination of total acidity and of divalent cations by ion chromatography with n-hexadecylphosphocholine as the stationary phase.
Journal: Journal of chromatography. A 20020517
Title: Miltefosine Zentaris.
Journal: Current opinion in investigational drugs (London, England : 2000) 20020401
Title: Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B.
Journal: Acta tropica 20020201
Title: New treatment for leishmaniasis is 95% effective.
Journal: Bulletin of the World Health Organization 20020101
Title: Effects of hexadecylphosphocholine on phosphatidylcholine and phosphatidylserine metabolism in human lymphoma cells.
Journal: Journal of experimental therapeutics & oncology 20020101
Title: Hexadecylphosphocholine does not influence phospholipase D and sphingomyelinase activity in human leukemia cells.
Journal: Journal of experimental therapeutics & oncology 20020101
Title: Hexadecylphosphocholine selectively upregulates expression of intracellular adhesion molecule-1 and class I major histocompatibility complex antigen in human monocytes.
Journal: Journal of experimental therapeutics & oncology 20020101
Title: Choline transport in Leishmania major promastigotes and its inhibition by choline and phosphocholine analogs.
Journal: Molecular and biochemical parasitology 20020101
Title: O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.
Journal: Journal of medicinal chemistry 20011206
Title: Randomized, double-blind, placebo-controlled, multicenter trial of 6% miltefosine solution, a topical chemotherapy in cutaneous metastases from breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20011101
Title: Drug resistance in Indian visceral leishmaniasis.
Journal: Tropical medicine & international health : TM & IH 20011101
Title: Development status of miltefosine as first oral drug in visceral and cutaneous leishmaniasis.
Journal: Medical microbiology and immunology 20011101
Title: Chemotherapy of cutaneous leishmaniasis: a review.
Journal: Medical microbiology and immunology 20011101
Title: Treatment of American cutaneous leishmaniasis with miltefosine, an oral agent.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011001
Title: Effects of miltefosine on various biochemical parameters in a panel of tumor cell lines with different sensitivities.
Journal: Biochemical pharmacology 20010915
Title: Growth inhibition of human mammary carcinoma by liposomal hexadecylphosphocholine: Participation of activated macrophages in the antitumor mechanism.
Journal: International journal of cancer 20010501
Title: MDR1 causes resistance to the antitumour drug miltefosine.
Journal: British journal of cancer 20010501
Title: Effects of hexadecylphosphocholine on thrombocytopoiesis.
Journal: European journal of cancer (Oxford, England : 1990) 20010301
Title: Modulation of phospholipase D by hexadecylphosphorylcholine: a putative novel mechanism for its antitumoral activity.
Journal: Oncogene 20010301
Title: Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis.
Journal: International journal of radiation oncology, biology, physics 20010201
Title: [Drug development from phospholipids].
Journal: Onkologie 20010201
Title: Separation and quantitation of alkylphosphocholines and analogues of different liposome formulations by HPTLC.
Journal: Journal of AOAC International 20010101
Title: [Treatment of visceral leishmaniasis: efficacy and limits of miltefosine].
Journal: Sante (Montrouge, France) 20010101
Title: Mononuclear cell recruitment, granuloma assembly, and response to treatment in experimental visceral leishmaniasis: intracellular adhesion molecule 1-dependent and -independent regulation.
Journal: Infection and immunity 20001101
Title: Recent strategies for the chemotherapy of visceral leishmaniasis.
Journal: Current opinion in infectious diseases 19991201
Title: Synthetic analogues of irlbacholine: a novel antifungal plant metabolite isolated from Irlbachia alata.
Journal: Journal of natural products 19990601
Title: Efficacy of anticancer alkylphosphocholines in Trypanosoma brucei subspecies.
Journal: Acta tropica 19970415
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