Home Imidazoles 583-39-1
583-39-1,MFCD00059348
Catalog No.:AA0033AL

583-39-1 | 2-Mercaptobenzimidazole

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Technical Information
Catalog Number:
AA0033AL
Chemical Name:
2-Mercaptobenzimidazole
CAS Number:
583-39-1
Molecular Formula:
C7H6N2S
Molecular Weight:
150.2009
MDL Number:
MFCD00059348
SMILES:
Sc1nc2c([nH]1)cccc2
UN Number:
2811
Properties
Properties
 
Form:
Solid  
MP:
300-304 °C(lit.)  
Refractive Index:
1.5500 (estimate)  
Solubility:
0.3g/l  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
142  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
XLogP3:
1.7  

Literature

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Title: Thyreostatic drugs, stability in bovine and porcine urine.

Journal: Analytical and bioanalytical chemistry 20120701

Title: Selective and sensitive recognition of Cu2+ in an aqueous medium: a surface-enhanced Raman scattering (SERS)-based analysis with a low-cost Raman reporter.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120514

Title: (Z)-2-(4-Chloro-benzyl-idene)benzo[d]thia-zolo[3,2-a]imidazol-3(2H)-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

Title: Electrochemically synthesized polymers in molecular imprinting for chemical sensing.

Journal: Analytical and bioanalytical chemistry 20120401

Title: 3-Fluoro-12H-benzimidazo[2,1-b][1,3]benzothia-zin-12-one.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: The conformations of two copper(I) complexes of 1H-benzimidazole-2(3H)-thione and thiosaccharinate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20120101

Title: Anticonvulsant evaluation of some newer benzimidazole derivatives: design and synthesis.

Journal: Acta poloniae pharmaceutica 20120101

Title: 2-Methyl-12H-benzimidazo[2,1-b][1,3]benzothia-zin-12-one.

Journal: Acta crystallographica. Section E, Structure reports online 20111201

Title: 2-(1H-1,3-Benzodiazol-2-ylsulfan-yl)-1-(4-chloro-phen-yl)ethanone.

Journal: Acta crystallographica. Section E, Structure reports online 20111001

Title: Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase.

Journal: European journal of medicinal chemistry 20110901

Title: 3-(2-Bromo-phen-yl)thia-zolo[3,2-a]benzimidazole.

Journal: Acta crystallographica. Section E, Structure reports online 20110901

Title: Synthesis and E/Z configuration determination of novel derivatives of 3-aryl-2-(benzothiazol-2'-ylthio) acrylonitrile, 3-(benzothiazol-2'-ylthio)-4-(furan-2''-yl)-3-buten-2-one and 2-(1-(furan-2''-yl)-3'-oxobut-1''-en-2-ylthio)-3-phenylquinazolin-4(3H)-one.

Journal: Molecules (Basel, Switzerland) 20110720

Title: In situ STM evidence for the adsorption geometry of three N-heteroaromatic thiols on Au(111).

Journal: Langmuir : the ACS journal of surfaces and colloids 20110621

Title: Backside SERS studies of inhibitor transport through polyelectrolyte films on Ag-substrates.

Journal: Journal of colloid and interface science 20110515

Title: Synthesis of 2-mercaptobenzimidazole derivatives as potential anti-microbial and cytotoxic agents.

Journal: Archiv der Pharmazie 20110501

Title: 1-Tosyl-2-[(1-tosyl-1H-benzimidazol-2-yl)methyl-sulfanyl]-1H-benzimidazole.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: Identification of indoline-2-thione analogs as novel potent inhibitors of α-melanocyte stimulating hormone induced melanogenesis.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Synthesis and controlled hydrolysis of organolanthanide complexes with mono- and dianionic benzimidazole-2-thiolate ligands.

Journal: Dalton transactions (Cambridge, England : 2003) 20101207

Title: Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening.

Journal: ChemMedChem 20101203

Title: 3-[2-(1H-Benzimidazol-2-ylsulfan-yl)eth-yl]-1,3-oxazolidin-2-one.

Journal: Acta crystallographica. Section E, Structure reports online 20101201

Title: Revisit to the reaction of o-phenylene diamine with thiosemicarbazide to give benzimidazole-2-thione rather than benzotriazine-2-thione and its glycosylation.

Journal: Nucleosides, nucleotides & nucleic acids 20100901

Title: Ratiometric surface enhanced Raman quantification of ligand adsorption onto a gold nanoparticle.

Journal: Analytical chemistry 20100701

Title: Novel benzo[d]imidazole-2(3H)-thiones as potent inhibitors of the alpha-melanocyte stimulating hormone induced melanogenesis in melanoma B16 cells.

Journal: Chemical & pharmaceutical bulletin 20100701

Title: Derivatives of benzimidazole pharmacophore: synthesis, anticonvulsant, antidiabetic and DNA cleavage studies.

Journal: European journal of medicinal chemistry 20100501

Title: [Antiarrhythmic properties of afobazole and other 2-mercaptobensimidazole derivatives].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20100501

Title: 1,3-Bis(ethoxy-meth-yl)-1H-benzimidazole-2(3H)-thione.

Journal: Acta crystallographica. Section E, Structure reports online 20100501

Title: Simultaneous spectrophotometric determination of 2-thiouracil and 2-mercaptobenzimidazole in animal tissue using multivariate calibration methods: concerns and rapid methods for detection.

Journal: Journal of food science 20100301

Title: Structural motifs and biological studies of new antimony(III) iodide complexes with thiones.

Journal: Inorganic chemistry 20100118

Title: [Effectiveness of combined application of ursosan and anxiolytic 2-mercaptobenzimidazole in early stage of cholelithiasis].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101

Title: Application of natural and modified hectorite clays as adsorbents to removal of Cr(VI) from aqueous solution--thermodynamic and equilibrium study.

Journal: Journal of hazardous materials 20091215

Title: Determination of thyreostats in urine and thyroid gland by ultra high performance liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: 2,2'-Bis(methyl-ene)-3,3'-(2-thioxo-2,3-dihydro-1H-benzimidazole-1,3-di-yl)dipropane-nitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20091101

Title: 3-[(1H-Benzimidazol-2-yl)sulfanyl-methyl]benzonitrile.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: A polynuclear d10-d10 metal complex with unusual near-infrared luminescence and high thermal stability.

Journal: Inorganic chemistry 20090406

Title: 1H-Benzimidazole-2(3H)-thione.

Journal: Acta crystallographica. Section E, Structure reports online 20090401

Title: Structure and properties of binuclear nitrosyl iron complex with benzimidazole-2-thiolyl.

Journal: Dalton transactions (Cambridge, England : 2003) 20090314

Title: New antimony(III) bromide complexes with thioamides: synthesis, characterization, and cytostatic properties.

Journal: Inorganic chemistry 20090302

Title: Determination of mercury in water and fish samples by cold vapor atomic absorption spectrometry after solid phase extraction on agar modified with 2-mercaptobenzimidazole.

Journal: Journal of hazardous materials 20090130

Title: [Specific effects of selective anxiolytic afobazole on the cardiovascular system].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20090101

Title: Syntheses and biological activities of benzimidazolo[2,1-b] benzo[e]thiazepin-5(10H)-ones.

Journal: Archiv der Pharmazie 20080101

Title: Synthesis, structural characterization and biological study of new organotin(IV), silver(I) and antimony(III) complexes with thioamides.

Journal: Journal of inorganic biochemistry 20080101

Title: Parallel synthesis of 2-sulphanylated bis-benzimidazoles on soluble polymer support.

Journal: Journal of combinatorial chemistry 20080101

Title: Synthesis, structural characterization, and biological studies of new antimony(III) complexes with thiones. The influence of the solvent on the geometry of the complexes.

Journal: Inorganic chemistry 20071015

Title: Modification of silica gel by attachment of 2-mercaptobenzimidazole for use in removing Hg(II) from aqueous media: a thermodynamic approach.

Journal: Journal of colloid and interface science 20070701

Title: Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds.

Journal: Pigment cell research 20070401

Title: [Synthesis and bioactivity of N- [4- ( benzimidazole-2-thio) phenyl] -N'-alkyl guanidine derivatives].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070201

Title: Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study.

Journal: Bioorganic & medicinal chemistry 20070115

Title: Benzofused tricycles based on 2-quinoxalinol.

Journal: Journal of combinatorial chemistry 20070101

Title: A novel approach for simultaneous determination of 2-mercaptobenzimidazole and derivatives of 2-thiouracil in animal tissue by gas chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: In vivo effects of afobazole (2-mercaptobenzimidazole derivative) on the 7,12-dimethylbenz [alpha]anthracene-induced oncogene and suppressor gene expression.

Journal: In vivo (Athens, Greece) 20070101

Title: The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties.

Journal: Bioinorganic chemistry and applications 20070101

Title: Green route for the heterocyclization of 2-mercaptobenzimidazole into beta-lactum segment derivatives containing -CONH- bridge with benzimidazole: Screening in vitro antimicrobial activity with various microorganisms.

Journal: Bioorganic & medicinal chemistry 20061215

Title: Respective contributions of polar vs enthalpy effects in the addition/fragmentation of mercaptobenzoxazole-derived thiyl radicals and analogues to double bonds.

Journal: The journal of physical chemistry. A 20061019

Title: Experimental and density functional theory study of the vibrational properties of 2-mercaptobenzimidazole in interaction with gold.

Journal: The journal of physical chemistry. A 20061005

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: An analytical method to screen for six thyreostatic drug residues in the thyroid gland and muscle tissues of food producing animals by liquid chromatography with ultraviolet absorption detection and liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International 20060101

Title: Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions.

Journal: Bioinorganic chemistry and applications 20060101

Title: Reactions Between Chalcogen Donors and Dihalogens/Interalogens: Typology of Products and Their Characterization by FT-Raman Spectroscopy.

Journal: Bioinorganic chemistry and applications 20060101

Title: Interaction of thioamides, selenoamides, and amides with diiodine.

Journal: Bioinorganic chemistry and applications 20060101

Title: Pressure-tuning Raman spectra of diiodine thioamide compounds: models for antithyroid drug activity.

Journal: Bioinorganic chemistry and applications 20060101

Title: Synthesis, structural characterization, and computational studies of novel diiodine adducts with the heterocyclic thioamides N-methylbenzothiazole-2-thione and benzimidazole-2-thione: implications with the mechanism of action of antithyroid drugs.

Journal: Inorganic chemistry 20051114

Title: Synthesis, antibacterial, antifungal activity and interaction of CT-DNA with a new benzimidazole derived Cu(II) complex.

Journal: European journal of medicinal chemistry 20051101

Title: Domino Michael addition-carbene rearrangement-cyclization reaction of 1-alkynyl(aryl)-lambda3-bromanes with 2-mercapto-1,3-benzazoles.

Journal: Chemical communications (Cambridge, England) 20051028

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: High-throughput microplate phosphorylation assays based on DevR-DevS/Rv2027c 2-component signal transduction pathway to screen for novel antitubercular compounds.

Journal: Journal of biomolecular screening 20050401

Title: New route to 3-alkylthiazolo[3,2-a]benzimidazole derivatives.

Journal: Molecules (Basel, Switzerland) 20050227

Title: [A comparative study of the effect of brazidole, amiodarone, sotalol, and hydroxyzine on potassium ionic channels of mollusks neurons].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20050101

Title: p53-dependent apoptotic mechanism of a new designer bimetallic compound tri-phenyl tin benzimidazolethiol copper chloride (TPT-CuCl2): in vivo studies in Wistar rats as well as in vitro studies in human cervical cancer cells.

Journal: The Journal of pharmacology and experimental therapeutics 20041001

Title: Capacitive chemical sensor for fenvalerate assay based on electropolymerized molecularly imprinted polymer as the sensitive layer.

Journal: Analytical and bioanalytical chemistry 20040501

Title: Characterization of a new class of selective nonsteroidal progesterone receptor agonists.

Journal: Steroids 20040301

Title: Potent mammalian cerebroprotection and neuronal cell death inhibition are afforded by a synthetic antioxidant analogue of marine invertebrate cell protectant ovothiols.

Journal: The European journal of neuroscience 20030901

Title: The role of HB-donor groups in the heterocyclic polar fragment of H3-antagonists. I. Synthesis and biological assays.

Journal: Farmaco (Societa chimica italiana : 1989) 20030901

Title: Chemical modification of milk xanthine oxidase with different modifiers.

Journal: Preparative biochemistry & biotechnology 20030801

Title: Comparative toxicokinetic/toxicodynamic study of rubber antioxidants, 2-mercaptobenzimidazole and its methyl substituted derivatives, by repeated oral administration in rats.

Journal: Archives of toxicology 20021201

Title: High-pressure Fourier transform micro-Raman spectroscopic investigation of diiodine-heterocyclic thioamide adducts.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001

Title: [Sorption rate equation of 2-mercaptopbenzimidazole chelating cellulose for some heavy metal ions].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20021001

Title: Square wave voltammetric sensing of uric acid using the self-assembly of mercaptobenzimidazole.

Journal: The Analyst 20020901

Title: Synthesis and antiparasitic activity of 1H-benzimidazole derivatives.

Journal: Bioorganic & medicinal chemistry letters 20020819

Title: Synthesis and preliminary evaluation of benzimidazole derivatives as antimicrobial agents.

Journal: European journal of medicinal chemistry 20020501

Title: Removal of mercury(II) from aqueous solutions and chlor-alkali industry wastewater using 2-mercaptobenzimidazole-clay.

Journal: Water research 20020301

Title: Determination of very low levels of dissolved mercury(II) and methylmercury in river waters by continuous flow with on-line UV decomposition and cold-vapor atomic fluorescence spectrometry after pre-concentration on a silica gel-2-mercaptobenzimidazol sorbent.

Journal: Talanta 20011224

Title: Differential pulse adsorption stripping voltammetric determination of copper(II) with 2-mercaptobenzimidazol at a hanging mercury-drop electrode.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010501

Title: Determination of mercaptobenzimidazol and other thyreostat residues in thyroid tissue and meat using high-performance liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20010406

Title: Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure.

Journal: Environmental health perspectives 19930701

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Tags:583-39-1 Molecular Formula|583-39-1 MDL|583-39-1 SMILES|583-39-1 2-Mercaptobenzimidazole |Organic_Building_Blocks