Title: Saikosaponin-d-mediated downregulation of neurogenesis results in cognitive dysfunction by inhibiting Akt/Foxg-1 pathway in mice.
Journal: Toxicology letters 20180301
Title: Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.
Journal: Journal of hepatology 20150301
Title: Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling.
Journal: Chemico-biological interactions 20141105
Title: Saikosaponin D disrupts platelet-derived growth factor-β receptor/p38 pathway leading to mitochondrial apoptosis in human LO2 hepatocyte cells: a potential mechanism of hepatotoxicity.
Journal: Chemico-biological interactions 20131025
Title: Effect of saikosaponin A on maintenance of intravenous morphine self-administration.
Journal: Neuroscience letters 20121031
Title: Solubilization of saikosaponin a by ginsenoside Ro biosurfactant in aqueous solution: mesoscopic simulation.
Journal: Journal of colloid and interface science 20121015
Title: Analysis of saikosaponins in rat plasma by anionic adducts-based liquid chromatography tandem mass spectrometry method.
Journal: Biomedical chromatography : BMC 20120701
Title: Saikosaponin-d inhibits β-conglycinin induced activation of rat basophilic leukemia-2H3 cells.
Journal: International immunopharmacology 20120701
Title: Metabolic fingerprinting by 1HNMR for discrimination of the two species used as Radix Bupleuri.
Journal: Planta medica 20120601
Title: Study on the noncovalent interactions of saikosaponins and cytochrome c by electrospray ionization mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20120415
Title: Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2.
Journal: Molecular medicine reports 20120301
Title: Large-scale production of saikosaponins through root culturing of Bupleurum falcatum L. using modified airlift reactors.
Journal: Journal of bioscience and bioengineering 20120101
Title: [Effects of interferon-alpha combined with saikosaponin on serum T lymphocyte subgroups and hepatic cytokines in mice with immune hepatic injury].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120101
Title: Species discrimination of Radix Bupleuri through the simultaneous determination of ten saikosaponins by high performance liquid chromatography with evaporative light scattering detection and electrospray ionization mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111215
Title: Interaction of the main components from the traditional Chinese drug pair Chaihu-Shaoyao based on rat intestinal absorption.
Journal: Molecules (Basel, Switzerland) 20111117
Title: [Optimization of the ultrasound assisted extraction of saikosaponins from Bupleurum falcatum using response surface methodology].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111101
Title: [Effect of Saikosaponins-d on reversing malignant phenotype of HepG2 cells in vitro].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20111001
Title: [Research on mechanism of energy metabolism disorders of rat's hepatoxicity induced by saikosaponins].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110901
Title: An LC-MS method for simultaneous determination of nine ginsenosides in rat plasma and its application in pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20110601
Title: Saikosaponins: a potential treatment option for systemic lupus erythematosus.
Journal: Irish journal of medical science 20110301
Title: Analysis of saikosaponins in Bupleuri Radix and Caihu-shugan-san using reversed-phase HPLC with pulsed amperometric detection.
Journal: Journal of separation science 20110301
Title: Fast and sensitive LC-DAD-ESI/MS method for analysis of saikosaponins c, a, and d from the roots of Bupleurum Falcatum (Sandaochaihu).
Journal: Molecules (Basel, Switzerland) 20110211
Title: Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.
Journal: Apoptosis : an international journal on programmed cell death 20110201
Title: Glaucasides A-C, three saikosaponins from Atriplex glauca L. var. ifiniensis (Caball) Maire.
Journal: Magnetic resonance in chemistry : MRC 20110201
Title: Inactivation of cystein-aspartic acid protease (caspase)-1 by saikosaponin A.
Journal: Biological & pharmaceutical bulletin 20110101
Title: Oleanene glycosides of the aerial parts and seeds of Bupleurum falcatum and the aerial parts of Bupleurum rotundifolium, and their evaluation as anti-hepatitis agents.
Journal: Chemical & pharmaceutical bulletin 20110101
Title: Transcriptome analysis of Bupleurum chinense focusing on genes involved in the biosynthesis of saikosaponins.
Journal: BMC genomics 20110101
Title: Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry.
Journal: Chemistry & biodiversity 20101201
Title: ['Dose-toxicity' relationship study on rat's chronic hepatoxicity of refined products of saikosaponin by alcohol elution].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
Title: [Breeding of new varieties 'zhongchai no. 2' and 'zhongchai no. 3' of Bupleurum chinense].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801
Title: [Study on dynamic accumulation of index components from Bupleurum chinense in various collecting periods].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801
Title: Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS.
Journal: Journal of separation science 20100701
Title: [Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100701
Title: Comparison between evaporative light scattering detection and charged aerosol detection for the analysis of saikosaponins.
Journal: Journal of chromatography. A 20100625
Title: Application of accelerated solvent extraction to the investigation of saikosaponins from the roots of Bupleurum falcatum.
Journal: Journal of separation science 20100601
Title: Optimization of supercritical fluid extraction of saikosaponins from Bupleurum falcatum with orthogonal array design.
Journal: Journal of separation science 20100401
Title: Inhibition of human renin activity by saponins.
Journal: Biomedical research (Tokyo, Japan) 20100401
Title: [Therapeutic effects and mechanism of saikosaponin-d in mice with bleomycin-induced pulmonary fibrosis].
Journal: Zhonghua yi xue za zhi 20100330
Title: Estrogen-like activities of saikosaponin-d in vitro: a pilot study.
Journal: European journal of pharmacology 20100125
Title: Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.
Journal: The American journal of Chinese medicine 20100101
Title: Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: [Differences of saikosaponin contents in Bupleurum chinense from habitats in Dongling Mountain & Wuling Mountain of Beijing].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201
Title: [Study on the optimal extraction process of chaihushugan powder].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20091101
Title: [Advances in mechanisms of saikosaponins in preventing and treating liver disease].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20091101
Title: Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis.
Journal: International immunopharmacology 20090701
Title: [Estrogen-like effects of saikosaponin-d in mice].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090701
Title: Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation.
Journal: Journal of cellular biochemistry 20090515
Title: Fast determination of saikosaponins in Bupleurum by rapid resolution liquid chromatography with evaporative light scattering detection.
Journal: Journal of pharmaceutical and biomedical analysis 20090501
Title: Evaluation of traditional Chinese herbal medicine: Chaihu (Bupleuri Radix) by both high-performance liquid chromatographic and high-performance thin-layer chromatographic fingerprint and chemometric analysis.
Journal: Journal of chromatography. A 20090313
Title: Application of centrifugal partition chromatography coupled with evaporative light scattering detection for the isolation of saikosaponins-a and -c from Bupleurum falcatum roots.
Journal: Journal of separation science 20090101
Title: Characterization and identification of saikosaponins in crude extracts from three Bupleurum species using LC-ESI-MS.
Journal: Journal of separation science 20081001
Title: [Inhibitory effects of saikosaponin a on rat hippocampal astrocyte activation in vitro].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001
Title: Localization and dynamic change of saikosaponin in root of Bupleurum chinense.
Journal: Journal of integrative plant biology 20080801
Title: Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Journal: Journal of medicinal food 20080601
Title: [Experimental study of saikosaponin-D (SSd) on lipid peroxidation of hepatic fibrosis on rat].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401
Title: Effects of Bupleurum scorzoneraefolium, Bupleurum falcatum, and saponins on nephrotoxic serum nephritis in mice.
Journal: Journal of ethnopharmacology 20080328
Title: [Determination of content of saikoside in Bupleurum Chinense from different sources].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080201
Title: Saireito and saikosaponin D prevent urinary protein excretion via glucocorticoid receptor in adrenalectomized WKY rats with heterologous-phase anti-GBM nephritis.
Journal: Nephron. Physiology 20080101
Title: [Effect of saikosaponin alpha on experimental epilepsy in rats].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070601
Title: [Separation and refine of Xiaoyao Pill by macroporous adsorption resin].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601
Title: A high-performance liquid chromatographic method for saikosaponin a quantification in rat plasma.
Journal: Biomedical chromatography : BMC 20070501
Title: [Aike mixture has good anti-inflammatory and analgesic effects on mice].
Journal: Zhonghua nan ke xue = National journal of andrology 20070501
Title: [Effect of saikosaponin-d on rat's glomerular mesangial cell proliferation and extracellular matrix hyperplasia in vitro].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20070401
Title: Mechanism of saikosaponin-d in the regulation of rat mesangial cell proliferation and synthesis of extracellular matrix proteins.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401
Title: Saikosaponin-d attenuates the development of liver fibrosis by preventing hepatocyte injury.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20070401
Title: Quality control of Chinese medicinal preparations LC/ESI(+)/MS/MS analyses of saikosaponins-a and -c as markers of Bupleuri radix samples.
Journal: Journal of pharmaceutical and biomedical analysis 20070219
Title: Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats.
Journal: World journal of gastroenterology 20070128
Title: Sho-saiko-to (Xiao-Chai-Hu-Tang) and crude saikosaponins inhibit hepatitis B virus in a stable HBV-producing cell line.
Journal: The American journal of Chinese medicine 20070101
Title: Upregulation of isoprenoid pathway genes during enhanced saikosaponin biosynthesis in the hairy roots of Bupleurum falcatum.
Journal: Molecules and cells 20061231
Title: Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice.
Journal: The Journal of pharmacy and pharmacology 20060901
Title: [Effect of saikosaponins-d on cyclooxygenase-2 expression of human hepatocellular carcinoma cell line SMMC-7721].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060901
Title: Visual detection of saikosaponins by on-membrane immunoassay and estimation of traditional Chinese medicines containing Bupleuri radix.
Journal: Biochemical and biophysical research communications 20060804
Title: [Saikosaponins inhibit increased glutamate and GABA expressions in the hippocampus of pentetrazole-induced slow kindling rats].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060801
Title: Antiviral effects of saikosaponins on human coronavirus 229E in vitro.
Journal: Clinical and experimental pharmacology & physiology 20060701
Title: [Effect of saikosaponins on glial fibrillary acidic protein expression in hippocampal astrocytes of pentetrazole-induced chronic kindling rats].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060401
Title: Effects of Saireito, a Japanese herbal medicine, on edema via antagonistic actions against aldosterone in anti-GBM nephritic rats.
Journal: Clinical and experimental nephrology 20060301
Title: A novel analytical ELISA-based methodology for pharmacologically active saikosaponins.
Journal: Fitoterapia 20060201
Title: [Effect of saikosaponins on epileptic seizure and EEG in pentetrazole-induced chronic kindling rats].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060201
Title: [Studies on fingerprints of Bupleurum chinense from Hebei Province with HPLC-UV].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060201
Title: [Progress in research on antitumor activity of saikosaponin and its mechanism].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060101
Title: Saikosaponin-d inhibits T cell activation through the modulation of PKCtheta, JNK, and NF-kappaB transcription factor.
Journal: Biochemical and biophysical research communications 20051230
Title: High performance liquid chromatographic assay of saikosaponins from radix Bupleuri in China.
Journal: Biological & pharmaceutical bulletin 20050901
Title: Cholesteryl hemisuccinate as a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing saikosaponin-d.
Journal: International journal of pharmaceutics 20050826
Title: Determination of saikosaponins a, c, and d in Bupleurum Chinese DC from different areas by capillary zone electrophoresis.
Journal: Analytical and bioanalytical chemistry 20050801
Title: [Cholesteryl hemisuccinate as liposomal membrane stabilizer and its use in the preparation of saikosaponin-D liposomes].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050701
Title: Therapeutic mechanism of Saikosaponin-d in anti-Thy1 mAb 1-22-3-induced rat model of glomerulonephritis.
Journal: Nephron. Experimental nephrology 20050101
Title: Saikosaponin C induces endothelial cells growth, migration and capillary tube formation.
Journal: Life sciences 20041231
Title: [Effect of saikosaponins on epileptic rat electroenciphalogram].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041201
Title: Involvement of p53, nuclear factor kappaB and Fas/Fas ligand in induction of apoptosis and cell cycle arrest by saikosaponin d in human hepatoma cell lines.
Journal: Cancer letters 20040930
Title: The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells.
Journal: Life sciences 20040723
Title: Determination of saikosaponin derivatives in Radix bupleuri and in pharmaceuticals of the chinese multiherb remedy xiaochaihu-tang using liquid chromatographic tandem mass spectrometry.
Journal: Analytical chemistry 20040715
Title: Development of an assay system for saikosaponin a using anti-saikosaponin a monoclonal antibodies.
Journal: Biological & pharmaceutical bulletin 20040101
Title: [Effect of chailing decoction and its active ingredients on experimental nephritis in rats].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20031001
Title: Cytotoxicity and anti-hepatitis B virus activities of saikosaponins from Bupleurum species.
Journal: Planta medica 20030801
Title: Antiproliferative constituents from Umbelliferae plants VI. New ursane-type saikosaponin analogs from the fruits of Bupleurum rotundifolium.
Journal: Chemical & pharmaceutical bulletin 20030401
Title: ERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a.
Journal: Oncogene 20030220
Title: Saikosaponin-A induces apoptotic mechanism in human breast MDA-MB-231 and MCF-7 cancer cells.
Journal: The American journal of Chinese medicine 20030101
Title: Characteristics and mechanism of enzyme secretion and increase in [Ca2+]i in Saikosaponin(I) stimulated rat pancreatic acinar cells.
Journal: World journal of gastroenterology 20020615
Title: Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma.
Journal: Phytotherapy research : PTR 20020601
Title: Induction of differentiation in rat C6 glioma cells with Saikosaponins.
Journal: Phytotherapy research : PTR 20020301
Title: Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia.
Journal: Planta medica 20020201
Title: Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers.
Journal: Applied microbiology and biotechnology 20011101
Title: Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells.
Journal: Biochemical and biophysical research communications 20010713
Title: Purification of saponin compounds in Bupleurum falcatum by solvent partitioning and preparative LC.
Journal: Bioscience, biotechnology, and biochemistry 20010701
Title: Inhibitory role of GDP on saikosaponin (I) stimulated enzymes secretion and rising of [Ca2+]i in rat pancreatic acini.
Journal: Acta pharmacologica Sinica 20010701
Title: Saikosaponin v-1 from roots of Bupleurum chinense DC.
Journal: Journal of Asian natural products research 20010101
Title: Effects of saikosaponin-d on aminonucleoside nephrosis in rats.
Journal: European journal of pharmacology 19860121
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