[1]Patent:CN106674115,2017,A.Locationinpatent:Paragraph0014;0015
[1]Patent:CN106674115,2017,A.Locationinpatent:Paragraph0016;0017
[1]Patent:CN106674115,2017,A.Locationinpatent:Paragraph0018;0019
[1]Patent:CN106674115,2017,A.Locationinpatent:Paragraph0020;0021
[1]Patent:CN106674115,2017,A.Locationinpatent:Paragraph0022;0023
Title: Licochalcone A from licorice root, an inhibitor of human hepatoma cell growth via induction of cell apoptosis and cell cycle arrest.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001
Title: Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160401
Title: Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.
Journal: Chemical research in toxicology 20151116
Title: Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151001
Title: Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It.
Journal: Chemical research in toxicology 20150817
Title: Anti-hepatitis C virus compounds obtained from Glycyrrhiza uralensis and other Glycyrrhiza species.
Journal: Microbiology and immunology 20140301
Title: Cranberry proanthocyanidins act in synergy with licochalcone A to reduce Porphyromonas gingivalis growth and virulence properties, and to suppress cytokine secretion by macrophages.
Journal: Journal of applied microbiology 20120801
Title: Licochalcone A prevents adipocyte differentiation and lipogenesis via suppression of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein pathways.
Journal: Journal of agricultural and food chemistry 20120523
Title: Guanylate cyclase activator YC-1 potentiates apoptotic effect of licochalcone A on human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathways.
Journal: European journal of pharmacology 20120515
Title: Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans.
Journal: Mycoses 20111101
Title: Design, synthesis, and evaluation of bromo-retrochalcone derivatives as protein tyrosine phosphatase 1B inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20110615
Title: Comparative trial of moisturizer containing licochalcone A vs. hydrocortisone lotion in the treatment of childhood atopic dermatitis: a pilot study.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20110601
Title: Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata.
Journal: Bioorganic & medicinal chemistry letters 20110101
Title: Reinvestigation of structure-activity relationship of methoxylated chalcones as antimalarials: synthesis and evaluation of 2,4,5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural β-asarone.
Journal: European journal of medicinal chemistry 20101101
Title: Licochalcones suppress degranulation by decreasing the intracellular Ca2+ level and tyrosine phosphorylation of ERK in RBL-2H3 cells.
Journal: International immunopharmacology 20100701
Title: Influence of subinhibitory concentrations of licochalcone A on the secretion of enterotoxins A and B by Staphylococcus aureus.
Journal: FEMS microbiology letters 20100601
Title: Subinhibitory concentrations of licochalcone A decrease alpha-toxin production in both methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates.
Journal: Letters in applied microbiology 20100201
Title: Licochalcone A potently inhibits tumor necrosis factor alpha-induced nuclear factor-kappaB activation through the direct inhibition of IkappaB kinase complex activation.
Journal: Molecular pharmacology 20091001
Title: Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway.
Journal: Journal of agricultural and food chemistry 20090923
Title: Antimalarial pharmacodynamics of chalcone derivatives in combination with artemisinin against Plasmodium falciparum in vitro.
Journal: European journal of medicinal chemistry 20090901
Title: Inhibitory effect of chalcones and their derivatives from Glycyrrhiza inflata on protein tyrosine phosphatase 1B.
Journal: Bioorganic & medicinal chemistry letters 20090901
Title: Licochalcone A significantly suppresses LPS signaling pathway through the inhibition of NF-kappaB p65 phosphorylation at serine 276.
Journal: Cellular signalling 20090501
Title: Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway.
Journal: International immunopharmacology 20090401
Title: Phytochemical licochalcone A enhances antimalarial activity of artemisinin in vitro.
Journal: Acta tropica 20090301
Title: Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation.
Journal: Biochemical pharmacology 20081215
Title: Structure and properties of licochalcone A-human serum albumin complexes in solution: a spectroscopic, photophysical and computational approach to understand drug-protein interaction.
Journal: Physical chemistry chemical physics : PCCP 20081128
Title: Functionalized chalcones with basic functionalities have antibacterial activity against drug sensitive Staphylococcus aureus.
Journal: European journal of medicinal chemistry 20080801
Title: Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice.
Journal: Basic & clinical pharmacology & toxicology 20080701
Title: 2-(3-aryl-3-oxopropen-1-yl)-9-tert-butyl-paullones: a new antileishmanial chemotype.
Journal: Journal of medicinal chemistry 20080214
Title: Antispasmodic activity of licochalcone A, a species-specific ingredient of Glycyrrhiza inflata roots.
Journal: The Journal of pharmacy and pharmacology 20071001
Title: Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information.
Journal: Biological & pharmaceutical bulletin 20070701
Title: Topoisomerase I inhibition and cytotoxicity of licochalcones A and E from Glycyrrhiza inflata.
Journal: Archives of pharmacal research 20070301
Title: Anti-inflammatory efficacy of Licochalcone A: correlation of clinical potency and in vitro effects.
Journal: Archives of dermatological research 20060601
Title: Inhibition by licochalcone A, a novel flavonoid isolated from liquorice root, of IL-1beta-induced PGE2 production in human skin fibroblasts.
Journal: The Journal of pharmacy and pharmacology 20051201
Title: Parasite mitochondria as a target of chemotherapy: inhibitory effect of licochalcone A on the Plasmodium falciparum respiratory chain.
Journal: Annals of the New York Academy of Sciences 20051101
Title: Cationic chalcone antibiotics. Design, synthesis, and mechanism of action.
Journal: Journal of medicinal chemistry 20050407
Title: Synthesis of prenylated benzaldehydes and their use in the synthesis of analogues of licochalcone A.
Journal: European journal of medicinal chemistry 20041101
Title: Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells.
Journal: Biochemical and biophysical research communications 20040910
Title: Isolation and purification of inflacoumarin A and licochalcone A from licorice by high-speed counter-current chromatography.
Journal: Journal of chromatography. A 20040903
Title: Natural antimycobacterial metabolites: current status.
Journal: Phytochemistry 20040401
Title: Transcriptional suppression of the HIV promoter by natural compounds.
Journal: Antiviral research 20030301
Title: In vitro antimycobacterial and antilegionella activity of licochalcone A from Chinese licorice roots.
Journal: Planta medica 20020501
Title: Chalcones from Chinese liquorice inhibit proliferation of T cells and production of cytokines.
Journal: International immunopharmacology 20020301
Title: Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.
Journal: Anticancer research 20000101
Title: Phenolic constituents of licorice. II. Structures of licopyranocoumarin, licoarylcoumarin and glisoflavone, and inhibitory effects of licorice phenolics on xanthine oxidase.
Journal: Chemical & pharmaceutical bulletin 19891101
Title: Anti-human immunodeficiency virus phenolics from licorice.
Journal: Chemical & pharmaceutical bulletin 19880601
Title: Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Sci Rep. 2016 May 17;6:26241.
Title: Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food and Chemical ToxicologyVolume 90, April 2016, Pages 112–122
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