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58749-23-8,MFCD20527294
Catalog No.:AA00EDG9

58749-23-8 | Licochalcone B

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98% by HPLC
in stock  
$113.00   $79.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00EDG9
Chemical Name:
Licochalcone B
CAS Number:
58749-23-8
Molecular Formula:
C16H14O5
Molecular Weight:
286.2794
MDL Number:
MFCD20527294
SMILES:
COc1c(C=CC(=O)c2ccc(cc2)O)ccc(c1O)O
Properties

Downstream Synthesis Route

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[2]Kim,Si-Jun;Kim,CheolGi;Yun,So-Ra;Kim,Jin-Kyung;Jun,Jong-Gab[BioorganicandMedicinalChemistryLetters,2014,vol.24,#1,p.181-185]

[3]Wang,Zengtao;Liu,Zhiguo;Cao,Yongkai;Paudel,Suresh;Yoon,Goo;Cheon,SeungHoon[BulletinoftheKoreanChemicalSociety,2013,vol.34,#12,p.3906-3908]

[4]CurrentPatentAssignee:HallymUniversityIndustry-AcademicCooperationFoundation;JeonJong-gap;KimSi-jun-KR101533010,2015,B1

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[2]Wang,Zengtao;Liu,Zhiguo;Cao,Yongkai;Paudel,Suresh;Yoon,Goo;Cheon,SeungHoon[BulletinoftheKoreanChemicalSociety,2013,vol.34,#12,p.3906-3908]

Literature

Title: Cao Y, et al. Licochalcone B, a chalcone derivative from Glycyrrhiza inflata, as a multifunctional agent for the treatment of Alzheimer's disease. Nat Prod Res. 2018 Oct 22:1-4.

Title: Jun-ichi Furusawa, et al. Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-kappaB p65 in LPS signaling pathway. Int Immunopharmacol. 2009 Apr;9(4):499-507.

Title: Ha-Na Oh, et al. Licochalcone B inhibits growth and induces apoptosis of human non-small-cell lung cancer cells by dual targeting of EGFR and MET. Phytomedicine. 2019 Oct;63:153014.

Title: Qiang Li, et al. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction. EMBO Rep. 2022 Feb 3;23(2):e53499.

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SDS
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Tags:58749-23-8 Molecular Formula|58749-23-8 MDL|58749-23-8 SMILES|58749-23-8 Licochalcone B
Catalog No.: AA00EDG9
58749-23-8,MFCD20527294
58749-23-8 | Licochalcone B
Pack Size： 1mg
Purity： 98% by HPLC
in stock
$113.00 $79.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00EDG9
Chemical Name: Licochalcone B
CAS Number: 58749-23-8
Molecular Formula: C16H14O5
Molecular Weight: 286.2794
MDL Number: MFCD20527294
SMILES: COc1c(C=CC(=O)c2ccc(cc2)O)ccc(c1O)O
Properties
Downstream Synthesis Route
85699-02-1    58749-23-8 

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

2144-08-3    58749-23-8 

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[2]Kim,Si-Jun;Kim,CheolGi;Yun,So-Ra;Kim,Jin-Kyung;Jun,Jong-Gab[BioorganicandMedicinalChemistryLetters,2014,vol.24,#1,p.181-185]

[3]Wang,Zengtao;Liu,Zhiguo;Cao,Yongkai;Paudel,Suresh;Yoon,Goo;Cheon,SeungHoon[BulletinoftheKoreanChemicalSociety,2013,vol.34,#12,p.3906-3908]

[4]CurrentPatentAssignee:HallymUniversityIndustry-AcademicCooperationFoundation;JeonJong-gap;KimSi-jun-KR101533010,2015,B1

85699-00-9    58749-23-8 

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

85698-99-3    58749-23-8 

[1]Islam,Azizul;Khan,SaeedAhmad;Krishnamurti,M.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1982,vol.21,#10,p.965-966]

[2]Wang,Zengtao;Liu,Zhiguo;Cao,Yongkai;Paudel,Suresh;Yoon,Goo;Cheon,SeungHoon[BulletinoftheKoreanChemicalSociety,2013,vol.34,#12,p.3906-3908]

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34221-41-5
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Submit
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