Catalog No.:AA00EG3K

59156-70-6 | Di(n-succinimidyl) adipate

Name: Name:Di(n-succinimidyl) adipate
Brand: AABLOCKS
SKU: AA00EG3K
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Rating: 90 (10 reviews)

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250mg

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$134.00 $94.00

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95%

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$254.00 $178.00

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$581.00 $407.00

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Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA00EG3K

Chemical Name:

Di(n-succinimidyl) adipate

CAS Number:

59156-70-6

Molecular Formula:

C14H16N2O8

Molecular Weight:

340.2854

MDL Number:

MFCD01318516

SMILES:

O=C(ON1C(=O)CCC1=O)CCCCC(=O)ON1C(=O)CCC1=O

Properties

BP:

495.3±55.0 °C(Predicted)

Form:

Solid

MP:

163-164℃ (ethanol acetonitrile )

Storage:

Room Temperature;

Computed Properties

Complexity:

516

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

-1.2

Downstream Synthesis Route

6066-82-6

124-04-9

59156-70-6

[1]Mishra,NarendraKumar;Joshi,KhashtiBallabh;Verma,Sandeep[MolecularPharmaceutics,2013,vol.10,#10,p.3903-3912]

[2]CurrentPatentAssignee:GLYTECHINC-EP3978023,2022,A1Locationinpatent:Paragraph0110;0112;0116

[3]CurrentPatentAssignee:GLYTECHINC-EP3978023,2022,A1Locationinpatent:Paragraph0110;0112;0116

[4]Zhang,Jingyu;Zhao,Xuan;Hou,Xuehui[AsianJournalofChemistry,2014,vol.26,#24,p.8569-8571]

[5]CurrentPatentAssignee:FEDERALSTATEUNITARYENTERPRISEOFRUSSIANFEDERATION-EP2397488,2019,B1Locationinpatent:Paragraph0115

[6]Harbachova,I.V.;Kuprienko,O.S.;Serchenya,T.S.;Sviridov,O.V.;Vashkevich,I.I.;Zilberman,A.I.[RussianJournalofBioorganicChemistry,2022,vol.48,#1,p.105-114][Bioorg.Khim.,2022,vol.48,#1,p.75-86]

[7]Postma,TobiasM.;Galloway,WarrenR.J.D.;Cougnon,FabienB.L.;Pantoş,G.Dan;Stokes,JamieE.;Spring,DavidR.[Synlett,2013,vol.24,#6,p.765-769]

[8]CurrentPatentAssignee:CENTAURITHERAPEUTICSLTD;CENTUARITHERAPEUTICSGBGB-WO2017/60729,2017,A1Locationinpatent:Page/Pagecolumn62

[9]Tanizawa;Mano;Kanaoka[ChemicalandPharmaceuticalBulletin,1990,vol.38,#2,p.464-466]

[10]Kalkhof,Stefan;Ihling,Christian;Mechtler,Karl;Sinz,Andrea[AnalyticalChemistry,2005,vol.77,#2,p.495-503]

[11]Yao,Ming-Hao;Yang,Jie;Du,Ming-Shuo;Song,Ji-Tao;Yu,Yong;Chen,Wei;Zhao,Yuan-Di;Liu,Bo[JournalofMaterialsChemistryB,2014,vol.2,#20,p.3123-3132]

[12]Zhuang,Chen;Tao,Fu-Rong;Cui,Yue-Zhi[ChemicalPapers,2016,vol.70,#4,p.505-514]

59156-70-6

N-(2-aminoethyl)-2-α-L-fucofuranosyl-(1->2)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->3)-α-D-galactopyranosyloxyacetamide

5-{2-2-(α-L-fucofuranosyl-(1->2)-β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->3)-α-D-galactopyranosyloxy)acetylaminoethylcarbamoyl}pentanoicacidN-hydroxy-succinimidylester

[1]Lay,Luigi;Panza,Luigi;Poletti,Laura;Prosperi,Davide;Canevari,Silvana;Perico,MariaElisa[EuropeanJournalofOrganicChemistry,2001,#22,p.4331-4336]

59156-70-6

C46H60N18O8

C52H68N18O11

[1]Weyermann,Philipp;Dervan,PeterB.[JournaloftheAmericanChemicalSociety,2002,vol.124,#24,p.6872-6878]

59156-70-6

25316-40-9

N-succinimidyl6-(doxorubicin-3'-N-yl)-5-oxohexanoate

[1]Chen,Qingqi;Sowa,DamianA.;Cai,Jianlin;Gabathuler,Reinhard[SyntheticCommunications,2003,vol.33,#14,p.2401-2421]

59156-70-6

Ac-Ala-Ala-Glu-Ala-Glu-Ala-Ala-Trp-Ala-Lys-Ala-Glu-Ala-Lys-Glu-Ala-NH2

Ac-Ala-Ala-Glu-Ala-Glu-Ala-Ala-Trp-Ala-Lys-Ala-Glu-Ala-Lys-Glu-Ala-NH2,cross-linkedwithhexanedioicacidbis(2,5-dioxopyrrolidin-1-yl)ester

[1]Fujimoto,Kazuhisa;Oimoto,Natsuko;Katsuno,Kahori;Inouye,Masahiko[ChemicalCommunications,2004,#11,p.1280-1281]

Literature

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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