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591778-68-6,MFCD25976696
Catalog No.:AA00EBJA

591778-68-6 | CP 640186

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Purity
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Price(USD)
Quantity
  
1mg
≥95%
in stock  
$63.00   $44.00
- +
5mg
98%
in stock  
$132.00   $93.00
- +
25mg
98%
in stock  
$339.00   $237.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EBJA
Chemical Name:
CP 640186
CAS Number:
591778-68-6
Molecular Formula:
C30H35N3O3
Molecular Weight:
485.6172
MDL Number:
MFCD25976696
SMILES:
O=C(N1CCOCC1)[C@@H]1CCCN(C1)C1CCN(CC1)C(=O)c1c2ccccc2cc2c1cccc2
Properties
Computed Properties
 
Complexity:
753  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
4.1  

Literature

Title: Design, synthesis, and structure-activity relationships of spirolactones bearing 2-ureidobenzothiophene as acetyl-CoA carboxylases inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20111101

Title: Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation.

Journal: Journal of medicinal chemistry 20101223

Title: (4-Piperidinyl)-piperazine: a new platform for acetyl-CoA carboxylase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Synthesis of spiro[chroman-2,4'-piperidin]-4-one derivatives as acetyl-CoA carboxylase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.

Journal: Bioorganic & medicinal chemistry letters 20061201

Title: Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with CP-640186.

Journal: Structure (London, England : 1993) 20040901

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SDS
Tags:591778-68-6 Molecular Formula|591778-68-6 MDL|591778-68-6 SMILES|591778-68-6 CP 640186