59198-70-8,MFCD00468095
Catalog No.:AA00JNU6

59198-70-8 | Diflucortolone 21-valerate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$46.00   $32.00
- +
50mg
≥98%
in stock  
$199.00   $139.00
- +
100mg
≥98%
in stock  
$373.00   $261.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00JNU6
Chemical Name:
Diflucortolone 21-valerate
CAS Number:
59198-70-8
Molecular Formula:
C27H36F2O5
Molecular Weight:
478.5685
MDL Number:
MFCD00468095
SMILES:
CCCCC(=O)OCC(=O)[C@H]1[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F
Properties
Computed Properties
 
Complexity:
943  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
4.2  

Literature

Title: Liquid chromatographic and spectrophotometric determination of diflucortolone valerate and isoconazole nitrate in creams.

Journal: Journal of AOAC International 20110101

Title: Lichen planus occurring after influenza vaccination: report of three cases and review of the literature.

Journal: Dermatology (Basel, Switzerland) 20100101

Title: Therapeutic use of topical corticosteroids in the vesiculobullous lesions of incontinentia pigmenti.

Journal: Clinical and experimental dermatology 20091201

Title: Papuloerythroderma associated with monoclonal gammopathy of undetermined significance.

Journal: The Journal of dermatology 20090401

Title: Occurrence of plantar pustular psoriasis during treatment with infliximab.

Journal: Journal of cutaneous medicine and surgery 20090101

Title: Superficial dermatomycoses worldwide: multinational treatment experience with a combination of isoconazole nitrate and diflucortolone valerate. Introduction.

Journal: Mycoses 20080901

Title: The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses.

Journal: Mycoses 20080901

Title: Successful therapy of tinea cruris with topical isoconazole in combination with a corticosteroid.

Journal: Mycoses 20080901

Title: The effective use of isoconazole nitrate and diflucortolone valerate cream in the treatment of inguino-femoral skin fold mycosis.

Journal: Mycoses 20080901

Title: Tinea cruris treated with a combined topical therapy containing isoconazole and a corticosteroid.

Journal: Mycoses 20080901

Title: Tinea corporis of the shin and chest successfully treated with a topical antifungal and corticosteroid cream.

Journal: Mycoses 20080901

Title: Tinea corporis treated with a combined topical therapy containing isoconazole and a corticosteroid.

Journal: Mycoses 20080901

Title: Tinea incognito due to Trichophyton rubrum responsive to topical therapy with isoconazole plus corticosteroid cream.

Journal: Mycoses 20080901

Title: Treatment of candidal intertrigo with a topical combination of isoconazole nitrate and diflucortolone valerate.

Journal: Mycoses 20080901

Title: Topical treatment of intertriginous candidal infection.

Journal: Mycoses 20080901

Title: Balanitis with eczematous perigenital intertriginous candidosis.

Journal: Mycoses 20080901

Title: Successful treatment of tinea pedis with a topical agent containing isoconazole nitrate and diflucortolone valerate.

Journal: Mycoses 20080901

Title: Step-wise treatment of athlete's foot (tinea pedis) using isoconazole combined with a corticosteroid followed by isoconazole alone.

Journal: Mycoses 20080901

Title: Exogenous Cushing's syndrome induced by surreptitious topical glucocorticosteroid overdose in infants with diaper dermatitis.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20071101

Title: Cushing's syndrome and adrenocortical insufficiency caused by topical steroids: misuse or abuse?

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20071101

Title: Paederus dermatitis in Sierra Leone.

Journal: Dermatology online journal 20061210

Title: Generalized mucinosis in a patient with erythroderma.

Journal: Dermatology (Basel, Switzerland) 20060101

Title: Central serous chorioretinopathy after local application of glucocorticoids for skin disorders.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20040501

Title: Effect of a topical steroid on gene expressions for chemokines in mice with contact hypersensitivity.

Journal: International immunopharmacology 20040101

Title: B M Henz, et al. Double-blind, Multicentre Analysis of the Efficacy of Borage Oil in Patients With Atopic Eczema. Br J Dermatol. 1999 Apr;140(4):685-8.

Title: V P Günzel, et al. [Toxicological Examination of Pure Diflucortolone Valerate and Its Formulations as Ointment, Fatty Ointment and Cream in Animal Experiments (Author's Transl) Arzneimittelforschung. 1976;26(7b):1476-9.

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SDS
Tags:59198-70-8 Molecular Formula|59198-70-8 MDL|59198-70-8 SMILES|59198-70-8 Diflucortolone 21-valerate
Catalog No.: AA00JNU6
59198-70-8,MFCD00468095
59198-70-8 | Diflucortolone 21-valerate
Pack Size: 10mg
Purity: ≥98%
in stock
$46.00 $32.00
Pack Size: 50mg
Purity: ≥98%
in stock
$199.00 $139.00
Pack Size: 100mg
Purity: ≥98%
in stock
$373.00 $261.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00JNU6
Chemical Name: Diflucortolone 21-valerate
CAS Number: 59198-70-8
Molecular Formula: C27H36F2O5
Molecular Weight: 478.5685
MDL Number: MFCD00468095
SMILES: CCCCC(=O)OCC(=O)[C@H]1[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F
Properties
Complexity: 943  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 9  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 34  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 4.2  
Literature fold

Title: Liquid chromatographic and spectrophotometric determination of diflucortolone valerate and isoconazole nitrate in creams.

Journal: Journal of AOAC International20110101

Title: Lichen planus occurring after influenza vaccination: report of three cases and review of the literature.

Journal: Dermatology (Basel, Switzerland)20100101

Title: Therapeutic use of topical corticosteroids in the vesiculobullous lesions of incontinentia pigmenti.

Journal: Clinical and experimental dermatology20091201

Title: Papuloerythroderma associated with monoclonal gammopathy of undetermined significance.

Journal: The Journal of dermatology20090401

Title: Occurrence of plantar pustular psoriasis during treatment with infliximab.

Journal: Journal of cutaneous medicine and surgery20090101

Title: Superficial dermatomycoses worldwide: multinational treatment experience with a combination of isoconazole nitrate and diflucortolone valerate. Introduction.

Journal: Mycoses20080901

Title: The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses.

Journal: Mycoses20080901

Title: Successful therapy of tinea cruris with topical isoconazole in combination with a corticosteroid.

Journal: Mycoses20080901

Title: The effective use of isoconazole nitrate and diflucortolone valerate cream in the treatment of inguino-femoral skin fold mycosis.

Journal: Mycoses20080901

Title: Tinea cruris treated with a combined topical therapy containing isoconazole and a corticosteroid.

Journal: Mycoses20080901

Title: Tinea corporis of the shin and chest successfully treated with a topical antifungal and corticosteroid cream.

Journal: Mycoses20080901

Title: Tinea corporis treated with a combined topical therapy containing isoconazole and a corticosteroid.

Journal: Mycoses20080901

Title: Tinea incognito due to Trichophyton rubrum responsive to topical therapy with isoconazole plus corticosteroid cream.

Journal: Mycoses20080901

Title: Treatment of candidal intertrigo with a topical combination of isoconazole nitrate and diflucortolone valerate.

Journal: Mycoses20080901

Title: Topical treatment of intertriginous candidal infection.

Journal: Mycoses20080901

Title: Balanitis with eczematous perigenital intertriginous candidosis.

Journal: Mycoses20080901

Title: Successful treatment of tinea pedis with a topical agent containing isoconazole nitrate and diflucortolone valerate.

Journal: Mycoses20080901

Title: Step-wise treatment of athlete's foot (tinea pedis) using isoconazole combined with a corticosteroid followed by isoconazole alone.

Journal: Mycoses20080901

Title: Exogenous Cushing's syndrome induced by surreptitious topical glucocorticosteroid overdose in infants with diaper dermatitis.

Journal: Journal of pediatric endocrinology & metabolism : JPEM20071101

Title: Cushing's syndrome and adrenocortical insufficiency caused by topical steroids: misuse or abuse?

Journal: Journal of pediatric endocrinology & metabolism : JPEM20071101

Title: Paederus dermatitis in Sierra Leone.

Journal: Dermatology online journal20061210

Title: Generalized mucinosis in a patient with erythroderma.

Journal: Dermatology (Basel, Switzerland)20060101

Title: Central serous chorioretinopathy after local application of glucocorticoids for skin disorders.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20040501

Title: Effect of a topical steroid on gene expressions for chemokines in mice with contact hypersensitivity.

Journal: International immunopharmacology20040101

Title: B M Henz, et al. Double-blind, Multicentre Analysis of the Efficacy of Borage Oil in Patients With Atopic Eczema. Br J Dermatol. 1999 Apr;140(4):685-8.

Title: V P Günzel, et al. [Toxicological Examination of Pure Diflucortolone Valerate and Its Formulations as Ointment, Fatty Ointment and Cream in Animal Experiments (Author's Transl) Arzneimittelforschung. 1976;26(7b):1476-9.

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