Title: Effect of decursin on the pharmacokinetics of theophylline and its metabolites in rats.
Journal: Journal of ethnopharmacology 20121121
Title: A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo.
Journal: Investigational new drugs 20121001
Title: Effect of decursinol angelate on the pharmacokinetics of theophylline and its metabolites in rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001
Title: Ultrafine Angelica gigas powder normalizes ovarian hormone levels and has antiosteoporosis properties in ovariectomized rats: particle size effect.
Journal: Journal of medicinal food 20121001
Title: A novel derivative of decursin, CSL-32, blocks migration and production of inflammatory mediators and modulates PI3K and NF-κB activities in HT1080 cells.
Journal: Cell biology international 20120701
Title: Decursin, an active compound isolated from Angelica gigas, inhibits fat accumulation, reduces adipocytokine secretion and improves glucose tolerance in mice fed a high-fat diet.
Journal: Phytotherapy research : PTR 20120501
Title: Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots.
Journal: Molecular biotechnology 20120201
Title: Quantitative determination of decursin, decursinol angelate, and decursinol in mouse plasma and tumor tissue using liquid-liquid extraction and HPLC.
Journal: Planta medica 20120201
Title: Structure-activity relationships for naturally occurring coumarins as β-secretase inhibitor.
Journal: Bioorganic & medicinal chemistry 20120115
Title: Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20111001
Title: Decursin from Angelicagigas Nakai induces apoptosis in RC-58T/h/SA#4 primary human prostate cancer cells via a mitochondria-related caspase pathway.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111001
Title: Decursin chemosensitizes human multiple myeloma cells through inhibition of STAT3 signaling pathway.
Journal: Cancer letters 20110201
Title: Protective effects of decursin and decursinol angelate against amyloid β-protein-induced oxidative stress in the PC12 cell line: the role of Nrf2 and antioxidant enzymes.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells.
Journal: Cancer letters 20101208
Title: Decursinol angelate blocks transmigration and inflammatory activation of cancer cells through inhibition of PI3K, ERK and NF-kappaB activation.
Journal: Cancer letters 20101001
Title: Cloning and characterization of phenylalanine ammonia-lyase and cinnamate 4-hydroxylase and pyranocoumarin biosynthesis in Angelica gigas.
Journal: Journal of natural products 20100827
Title: Hypopigmentary action of dihydropyranocoumarin D2, a decursin derivative, as a MITF-degrading agent.
Journal: Journal of natural products 20100528
Title: Decursin prevents cisplatin-induced apoptosis via the enhancement of antioxidant enzymes in human renal epithelial cells.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Decursin inhibits VEGF-mediated inner blood-retinal barrier breakdown by suppression of VEGFR-2 activation.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090901
Title: Effects of diumancal and decursinol on 5-hydroxytryptamine level in rat brain.
Journal: Georgian medical news 20090901
Title: Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.
Journal: Journal of natural products 20090601
Title: The analgesic effect of decursinol.
Journal: Archives of pharmacal research 20090601
Title: A novel (S)-(+)-decursin derivative, (S)-(+)-3-(3,4-dihydroxy-phenyl)-acrylic acid 2,2-dimethyl-8-oxo-3,4-dihydro-2H,8H-pyrano[3,2-g]chromen-3-yl-ester, inhibits ovalbumin-induced lung inflammation in a mouse model of asthma.
Journal: Biological & pharmaceutical bulletin 20090301
Title: In vivo anti-cancer activity of Korean Angelica gigas and its major pyranocoumarin decursin.
Journal: The American journal of Chinese medicine 20090101
Title: Decursin inhibits retinal neovascularization via suppression of VEGFR-2 activation.
Journal: Molecular vision 20090101
Title: Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects.
Journal: PloS one 20080101
Title: Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum.
Journal: Planta medica 20071101
Title: Mechanism-based inactivation of cytochrome P450 2A6 by decursinol angelate isolated from Angelica Gigas.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071001
Title: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.
Journal: Acta pharmacologica Sinica 20070901
Title: Decursinol and decursin protect primary cultured rat cortical cells from glutamate-induced neurotoxicity.
Journal: The Journal of pharmacy and pharmacology 20070601
Title: A novel class of pyranocoumarin anti-androgen receptor signaling compounds.
Journal: Molecular cancer therapeutics 20070301
Title: [Inhibitory effects of 11 coumarin compounds against growth of human bladder carcinoma cell line E-J in vitro].
Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20070101
Title: Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells.
Journal: Breast cancer research : BCR 20070101
Title: Decursin inhibits induction of inflammatory mediators by blocking nuclear factor-kappaB activation in macrophages.
Journal: Molecular pharmacology 20060601
Title: Molecular target of decursins in the inhibition of lipid droplet accumulation in macrophages.
Journal: Biological & pharmaceutical bulletin 20060501
Title: Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer.
Journal: Cancer research 20060101
Title: Decursin and PDBu: two PKC activators distinctively acting in the megakaryocytic differentiation of K562 human erythroleukemia cells.
Journal: Leukemia research 20051201
Title: Involvement of PKC and ROS in the cytotoxic mechanism of anti-leukemic decursin and its derivatives and their structure-activity relationship in human K562 erythroleukemia and U937 myeloleukemia cells.
Journal: Cancer letters 20050608
Title: A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells.
Journal: Cancer research 20050201
Title: Four new neuroprotective dihydropyranocoumarins from Angelica gigas.
Journal: Journal of natural products 20050101
Title: Protection against beta-amyloid peptide-induced memory impairment with long-term administration of extract of Angelica gigas or decursinol in mice.
Journal: Progress in neuro-psychopharmacology & biological psychiatry 20040101
Title: Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas.
Journal: Archives of pharmacal research 20030901
Title: Anti-tumor activities of decursinol angelate and decursin from Angelica gigas.
Journal: Archives of pharmacal research 20030901
Title: Antinociceptive mechanisms of orally administered decursinol in the mouse.
Journal: Life sciences 20030613
Title: Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice.
Journal: Planta medica 20030301
Title: Decursin from Angelica gigas mitigates amnesia induced by scopolamine in mice.
Journal: Neurobiology of learning and memory 20030101
Title: Coumarins isolated from Angelica gigas inhibit acetylcholinesterase: structure-activity relationships.
Journal: Journal of natural products 20010501
Title: Ahn KS,et al. Decursin: a cytotoxic agent and protein kinase C activator from the root of Angelica gigas. Planta Med. 1996;62(1):7-9.
Title: Li J, et al. Decursin inhibits the growth of HepG2 hepatocellular carcinoma cells via Hippo/YAP signaling pathway. Phytother Res. 2018;32(12):2456-2465.
Title: Kim S, et al. Decursin inhibits tumor growth, migration, and invasion in gastric cancer by down-regulating CXCR7 expression. Am J Cancer Res. 2019;9(9):2007-2018. Published 2019 Sep 1.
