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Title: Chimeric mice with humanized liver.
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Title: The effect of a long term epidural infusion of ropivacaine on CYP2D6 activity.
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Title: In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver.
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Title: 3,4-Dehydrodebrisoquine, a novel debrisoquine metabolite formed from 4-hydroxydebrisoquine that affects the CYP2D6 metabolic ratio.
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Title: Influence of chronic renal failure on stereoselective metoprolol metabolism in hypertensive patients.
Journal: Journal of clinical pharmacology 20051201
Title: Determination of debrisoquine and 4-hydroxydebrisoquine by high-performance liquid chromatography: application to the evaluation of CYP2D6 genotype and debrisoquine metabolic ratio relationship.
Journal: Clinical chemistry and laboratory medicine 20050101
Title: The hepatic and intestinal metabolic activities of P450 in rats with surgery- and drug-induced renal dysfunction.
Journal: Pharmaceutical research 20031001
Title: Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test.
Journal: Clinical pharmacology and therapeutics 20011001
Title: Characterization of stereoselectivity and genetic polymorphism of the debrisoquine hydroxylation in man via analysis of urinary debrisoquine and 4-hydroxydebrisoquine by capillary electrophoresis.
Journal: Electrophoresis 19970901
