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595-40-4,MFCD00145255
Catalog No.:AA00IAHG

595-40-4 | L-Isovaline

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100mg
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$37.00   $26.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IAHG
Chemical Name:
L-Isovaline
CAS Number:
595-40-4
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD00145255
SMILES:
C[C@@](C(=O)O)(CC)N C5H11NO2
Properties
Properties
 
BP:
213.6°C at 760 mmHg  
Form:
Solid  
MP:
289.39°C (estimate)  
Refractive Index:
1.4650 (estimate)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
103  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
-2.3  

Literature

Title: GABA(B) receptor-mediated selective peripheral analgesia by the non-proteinogenic amino acid, isovaline.

Journal: Neuroscience 20120628

Title: R-Isovaline: a subtype-specific agonist at GABA(B)-receptors?

Journal: Neuroscience 20120110

Title: Photostability of Iiovaline and its precursor 5-Ethyl-5- methylhydantoin exposed to simulated space radiations.

Journal: International journal of molecular sciences 20120101

Title: Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity.

Journal: Epilepsia 20111101

Title: Distribution and stable isotopic composition of amino acids from fungal peptaibiotics: assessing the potential for meteoritic contamination.

Journal: Astrobiology 20110301

Title: Configurational assignment of D- and L-isovalines in intact, natural, and synthetic peptides by 2D-NMR spectroscopy.

Journal: Chemistry & biodiversity 20100601

Title: Analgesic properties of the novel amino acid, isovaline.

Journal: Anesthesia and analgesia 20100401

Title: (S)-alpha-methyl,alpha-amino acids: a new stereocontrolled synthesis.

Journal: Amino acids 20100301

Title: Isovaline causes inhibition by increasing potassium conductance in thalamic neurons.

Journal: Neuroscience 20091215

Title: Aib and iva in the biosphere: neither rare nor necessarily extraterrestrial.

Journal: Chemistry & biodiversity 20090101

Title: Studies on the selective trifluoroacetolytic scission of native peptaibols and model peptides using HPLC and ESI-CID-MS.

Journal: Chemistry & biodiversity 20081101

Title: Sequence diversity of the peptaibol antibiotic suzukacillin-A from the mold Trichoderma viride.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20060501

Title: Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum.

Journal: The Journal of antibiotics 20060501

Title: Fungal biosynthesis of non-ribosomal peptide antibiotics and alpha, alpha-dialkylated amino acid constituents.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20050601

Title: Prebiotic amino acids as asymmetric catalysts.

Journal: Science (New York, N.Y.) 20040220

Title: A simple and rapid enzymatic assay for the branched-chain alpha-ketoacid dehydrogenase complex using high-performance liquid chromatography.

Journal: Journal of inherited metabolic disease 20040101

Title: Antibodies directed against L and D isovaline using a chemical derivatizing reagent for the measurement of their enantiomeric ratio in extraterrestrial samples: first step-production and characterization of antibodies.

Journal: Chirality 20020601

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